CN109602805A - Passive sleeping composition and its application - Google Patents
Passive sleeping composition and its application Download PDFInfo
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- CN109602805A CN109602805A CN201910035424.4A CN201910035424A CN109602805A CN 109602805 A CN109602805 A CN 109602805A CN 201910035424 A CN201910035424 A CN 201910035424A CN 109602805 A CN109602805 A CN 109602805A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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Abstract
The embodiment of the invention discloses a kind of passive sleeping composition and its applications.Wherein, the passive sleeping composition includes: to pacify ancient lavender, marjoram, sweet orange, Petitgrain and flores aurantii.The composition plays the role of the pressure relieving mental strain and helping sleep that relaxes by the mutual cooperation of a variety of natural constituents.Its central nervous system that human body is acted in a manner of detected by scent, without side-effects or addicted risk, can be used for a long time, have a good application prospect.
Description
Technical field
The present invention relates to health product technology field more particularly to a kind of passive sleeping composition and its applications.
Background technique
As social life pressure is increasing, the influence of Diet lifestyle etc., in today's society, it is difficult to fall asleep or
The phenomenon of insomnia etc. starts widely to occur, and very big influence is caused to the normal life of people.In order to solve these sleeps
The problem of, people generally use alcohol, hypnotic, melatonin and antihistamine etc. to treat.
But these therapeutic agents also bring along the side effect of highly significant while can be improved sleep quality.Tool
For body, alcohol has very strong sympathetic stimulation to act on, can be several although the brain lethargic sleep consciousness of short time is vast and hazy
Occur after hour, least sleep is more difficult to fall asleep instead, and the long-term alcohol that relies on not only causes cranial nerve to injure, it is easier to make
Sympathicoblast nerve is overexcited and difficulty falling asleep.
And the side effect of hypnotic and additive all quite big, such as sleeping drug-Barbiturates of the first generation
(barbiturates).Since it can activate the neurotransmitter (GABA) of inhibition simultaneously and inhibit excitatoty amino
Sour (glutamate), although calm and sleeping effect is good, because nervous centralis can be reduced to carbon dioxide in blood (CO2)
With the susceptibility of oxygen (O2), cause respiration inhibition, also will affect cardiovascular system, cause that blood pressure decline, heartbeat is slack-off shows
As.When overdose, there are it is lethal a possibility that.
In addition, the sleeping drug of first generation the problem of there are also habituation and drug resistances, when long-term use, must increase dosage
Identical sleeping or sedation can be reached.
On the basis of first generation sleeping drug, there are also second generation sleeping drug-BZD of some improvement
(benzodiazepine) class drug.It is equally by the neurotransmitter (GABA) of activation inhibition, to reach calmness
Sleeping, antianxiety, anti-spasm and effect of flaccid muscles.
Although such drug substantially improves the inhibition to cardiovascular and respiratory system, there is no excessive fatal danger.
But because its active position relates to the hippocampal gyrus area for being responsible for memory in spinal cord relevant to coordination and brain,
It is easy when waking up in the morning, the side effects such as the similar instability of gait of (hangover) of being still drank after a night, headache, dizzy sense occurs, and lose memory.
Melatonin (Melatonin) is a kind of hormone related with physiological clock, can be applied to adjust sleep,
The waiting time is helped before reduction is fallen asleep, and increases total sleep time, improves whole sleep quality.But when used for a long time may
There is phenomena such as vomiting, drowsiness, and influences the ability that body voluntarily generates melatonin.
Antihistaminicum class drug is mainly used for treating the drug that skin plays rash and nose allergy, for avoiding caused by histamine
Adverse reaction.But it is easy to cause very more side effects, it is common in tired, out of strength, dizziness, headache, dry, eyesight mould
Paste, constipation, dysuria or retention of urine etc..Possibly even there is mental excitation, insomnia, muscular tremor, rhythm of the heart mistake in some patientss
The problems such as normal digestive discomfort.
Since existing Sedative drugs all have above one or more kinds of detrimental effects, it is very easy to generate
Side effect.Therefore, a kind of new there is an urgent need to provide, it is not easy to cause side effect while sleeping problems can be effectively relieved
Health treatment.
Summary of the invention
In view of the above technical problems, the embodiment of the invention provides a kind of passive sleeping composition and its applications, to solve
Present Sedative drugs function and effect are limited, and side effect is larger and the problem of can not being used for a long time.
The first aspect of the embodiment of the present invention provides a kind of passive sleeping composition.Wherein, the passive sleeping composition
It include: to pacify ancient lavender, marjoram, sweet orange, Petitgrain and flores aurantii.
Optionally, count by weight percentage, the ratio for pacifying ancient lavender, marjoram, sweet orange, Petitgrain and flores aurantii
Example is 4:1:2:2:1.
Optionally, in the passive sleeping composition described in every 10g, including the following raw material component:
Optionally, the passive sleeping composition is the pure essential oil of not diluted formula.
Optionally, the pure essential oil of the formula of passive sleeping by pacify ancient Lavender, marjoram essential oil, sweet orange oil,
Bigarabe leaf essential oil and flores aurantii essential oil are mixed to form by setting ratio.
Optionally, the pure essential oil of the formula of passive sleeping has the taste mode of setting, is sent out by the smell of human body
Wave physiological activity.
Optionally, the preceding taste of the pure essential oil of the formula of passive sleeping is by bigarabe leaf essential oil and the polynary orange of flores aurantii essential oil
Taste combination is taken out of.
Optionally, the flowers and plants perfume (or spice) of the ancient Lavender of the peace and marjoram essential oil is mixed with the sweetness of taste orange in preceding taste
And it distributes therewith.
Optionally, the pure essential oil of the formula of passive sleeping includes limonene, linalool and bergamio.
The second aspect of the embodiment of the present invention additionally provides passive sleeping composition as described above on reducing mobility
Application.
A kind of pure essential oil of formula of passive sleeping is provided in technical solution provided in an embodiment of the present invention, passes through a variety of days
The pressure relieving mental strain and helping sleep that relaxes is played the role of in the mutual cooperation of right component.Its maincenter mind that human body is acted in a manner of detected by scent
Through system, without side-effects or addicted risk can be used for a long time, have a good application prospect.
Detailed description of the invention
Fig. 1 is one embodiment schematic diagram of brain wave mode provided in an embodiment of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, those skilled in the art's every other implementation obtained without creative efforts
Example, shall fall within the protection scope of the present invention.
It should be noted that be expressed " being fixed on " another element when element, it can directly on the other element,
Or there may be one or more elements placed in the middle therebetween.When an element is expressed " connection " another element, it can be with
It is directly to another element or there may be one or more elements placed in the middle therebetween.Used in this specification
The orientation or position of the instructions such as term "vertical", "horizontal", "left" and "right", "upper", "lower", "inner", "outside", " bottom "
Relationship is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description of the present invention and simplification of the description, without referring to
Show or imply that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot manage
Solution is limitation of the present invention.In addition, term " first ", " second " etc. are used for description purposes only, and should not be understood as instruction or
Imply relative importance.
Unless otherwise defined, technical and scientific term all used in this specification is led with technology of the invention is belonged to
The normally understood meaning of the technical staff in domain is identical.Used term is only in the description of the invention in this specification
The purpose of description specific embodiment is not intended to the limitation present invention.Term "and/or" used in this specification includes
Any and all combinations of one or more related listed items.In addition, invention described below difference is implemented
Technical characteristic involved in mode can be combined with each other as long as they do not conflict with each other.
The embodiment of the invention provides a kind of passive sleeping compositions.Wherein, the passive sleeping composition includes as follows
Component: pacify ancient lavender, marjoram, sweet orange, Petitgrain and flores aurantii.
Pacifying ancient lavender (Lavandula angustifolia), be otherwise known as narrow-leaved lavender, is a kind of with strong fragrant
The plant of taste can be made into pillow etc., as mild sedative, to play the work for relieving stress and calming down nerve
With.
Marjoram (Origanum majorana L) is the herbaceous plant with irritation bitterness fragrance slightly.It has
Very high medical value is widely used in calm spasm, the improvement of the symptoms such as headache or insomnia.Lavender and marjoram etc.
It with the combination of the Petitgrain and flores aurantii and sweet orange with pressure relieve stagnation of relaxing, can cooperate, be provided commonly for improving because pressure is big
Wakefulness state caused by and.
Specifically, count by weight percentage, in the passive sleeping composition, the ancient lavender of the peace, marjoram,
Sweet orange, Petitgrain and the ratio of flores aurantii are 4:1:2:2:1, to obtain optimal function and effect.
Passive sleeping composition provided in an embodiment of the present invention, may adapt to have be suitble to difficulty falling asleep, evening to sleep, pressure
Greatly, it works and rests irregular and often go on business, is frequently necessary to overtime work at night and leads to Depth of sleep time inadequate crowd.
On daytime in use, can concentrate on for user, work more absorbed.And 8 points of uses later at night,
The parasympathetic nerve that user can then be started, makes body and mind activity ease up, Depth of sleep is promoted to increase, and improves because pressure is big, evening sleeps
And lead to the insufficient sleeping problems of deep sleep.
It is excessive with 100 pressure, when leading to sleeping at night, tested for 30 minutes or more the patients that can not still fall asleep
Research the result shows that: using after the passive sleeping composition, 85% or more patient falls asleep's time shortens, 98% trouble
The brain wave of person is shown, is shortened before falling asleep from the time that B wave enters the δ wave that α wave enters back into deep sleep, it was demonstrated that time for falling asleep contracting
Short and Depth of sleep improves, and can improve because of insomnia caused by nervous, and the rest of enhancing brain, reduce anxiety water
It is flat.
Specifically, example according to above-mentioned weight ratio, in the passive sleeping composition described in every 10g, including the following raw material component:
Amazing to be, when using said components ratio, the passive sleeping composition being mixed to form can have more
Good calming soporific effect cooperates more preferably between various raw material components.It may be because using provided by the above embodiment
(ratio for pacifying ancient lavender, marjoram, sweet orange, Petitgrain and flores aurantii is 4:1:2:2:1), lemon when raw material components ratio
The concentration highest of alkene (Limonene) substance.
Limonene is the ingredient that the anti-sorrow of pressure of most relaxing is widely used in mood medical treatment, it helps promote parasympathetic nerve,
Brain is allowed to enter relaxation state of releiving.
In the preferred embodiment, the passive sleeping composition can be the not diluted pure essential oil of formula.It has compared with
High volatility, can by directly by smell in a manner of play the effect of bioactive substance in raw material components.
Specifically, the pure essential oil of formula of passive sleeping can by pacify ancient Lavender, marjoram essential oil, sweet orange oil,
Bigarabe leaf essential oil and flores aurantii essential oil are mixed to form by setting ratio.The setting ratio can be using disclosed in above-described embodiment
Weight ratio, to obtain optimal using effect.
Compared with traditional drug or health care product, smell and nerve of the pure essential oil of formula of the passive sleeping through human body
Conduction plays a role, and not any is additive, and action speed is very fast, and muscle and nerve can be enabled rapidly to loosen, coordinated
Body nervous system, thus on daytime in use, people can be helped to enter the state of absorbed sympathetic nerve secretion, and at night
Between when, then body can be assisted naturally to enter parasympathetic state, in the state comfortably loosened.
Its specific principle process is as follows: before aromatic molecules are detected by the cilium of olfactory nucleus, elder generation exists
It is dissolved in mucus.Maincenter can be stimulated through glomeruli in the form of electrochemical pulse for the smell induction of aromatic molecules later
The parasympathetic nerve of nervous system has reached loosening all muscles, and rhythm of the heart decline, breathing is gentle, into the preparation state of sleep early period.
The region that brain administers smell is located among mysterious limbic system, limbic system, coupled hypothalamus and
Pituitary gland will receive extraneous induction and stimulation, thus cause a series of reaction in terms of the spirit and the human body of human body.Brain
Middle smell induction zone is still a kind of most basic and most direct feeling.Limbic system is related with the natural reaction of the mankind, such as feelings
Sense, intuition, memory, creativity, starvation, thirsty, sleep state, sexual desire.
Therefore, physiological activity can be played by smell, guide mood by suitable taste mode, keep it flat
With loosen, help preferably to enter sleep state.
Specifically, polynary orange taste group of the preceding taste of the pure essential oil of formula of passive sleeping by bigarabe leaf essential oil and flores aurantii essential oil
Crossed belt goes out.Further, the grassland sense for making us loose is flowed out therewith followed by the ancient lavender of peace and marjoram.The sugariness of orange,
It is fragrant to have integrated the far-reaching flowers and plants of the length and breadth of land, has been that one kind has both the feeling unfolded, and make us quiet and comfortable.It uses within 10 minutes before sleeping
It allows to brain wave from α wave to δ wave, into loosening and absorbed breathing, body is allowed naturally to walk with parasympathetic running
Into the sleep state of no pressure.
GC/MS gas chromatographic analysis is carried out as the result is shown to the pure essential oil of formula of passive sleeping: there is the anti-melancholy of resistance to compression
Limonene (Limonene) reaching peak-peak ten minutes later.And it is used to induce cranial nerve to loosen and stimulate parasympathetic refreshing
The chemical substance linalool (Linalool) and bergamio (Camphor) of warp also successively occur.Between many kinds of substance
Mutually collaboration advantageously reduces nervimuscular mobility, can achieve the effect releived and loosened, and it is big to be suitable for pressure, burnt
Consider, difficulty falling asleep, shallow dormancy disease person uses.
In some embodiments, essential oil can be dripped in the quadrangle of sleep pillow used before sleeping, and made indoors
The aroma diffusing of essential oil is carried out with fragrant atmosphere machine etc., the taste for enabling relaxation releive is full of entire room.In further embodiments, daily to make
Used time can also use anion scent diffusion equipment, bath, other any suitable ways such as champignon bag or aroma diffusing stone distribute essential oil
Taste.
Fig. 1 is brain wave type (the Scalp Potential change of detection subject under different conditions provided in an embodiment of the present invention
Change and determine).
To having used the user of essential oil to carry out brain wave test discovery, subject enters after the 5th minute of test
Quiet α wavy state when closing mesh, brain activity are tranquil.Moreover, subject, in sleep, the time span of deep sleep is compared with one
As people more 20 minutes or so.
Further the mouse experiment of passive sleeping essential oil is confirmed, the smell of the essential oil can play significant calm work
With can cooperate with sleeping time, the angst resistance effect of enhancing barbital induction, reduce motility and prevent caused by caffeine living
It is dynamic excessive.It has similar effect compared with somnifacient and sedative in terms for the treatment of insomnia, can increase drowsiness and promote to put
Pine.
It, can according to the technique and scheme of the present invention and this hair it is understood that for those of ordinary skills
Bright design is subject to equivalent substitution or change, and all these changes or replacement all should belong to the guarantor of appended claims of the invention
Protect range.
Claims (10)
1. a kind of passive sleeping composition, which is characterized in that the passive sleeping composition include: pacify ancient lavender, marjoram,
Sweet orange, Petitgrain and flores aurantii.
2. passive sleeping composition according to claim 1, which is characterized in that count by weight percentage, the peace is ancient
Lavender, marjoram, sweet orange, Petitgrain and flores aurantii ratio be 4:1:2:2:1.
3. passive sleeping composition according to claim 1, which is characterized in that the passive sleeping composition described in every 10g
In, including the following raw material component:
4. passive sleeping composition according to claim 1-3, which is characterized in that the passive sleeping composition
For for the not diluted pure essential oil of formula.
5. passive sleeping composition according to claim 4, which is characterized in that the pure essential oil of the formula of passive sleeping by
Pacify ancient Lavender, marjoram essential oil, sweet orange oil, bigarabe leaf essential oil and flores aurantii essential oil to be mixed to form by setting ratio.
6. passive sleeping composition according to claim 5, which is characterized in that the pure essential oil tool of the formula of passive sleeping
There is the taste mode of setting, physiological activity is played by the smell of human body.
7. passive sleeping composition according to claim 6, which is characterized in that the pure essential oil of the formula of passive sleeping
Preceding taste is combined by the polynary orange taste of bigarabe leaf essential oil and flores aurantii essential oil and is taken out of.
8. passive sleeping composition according to claim 6, which is characterized in that the ancient Lavender of the peace and Ma Yu
The flowers and plants perfume (or spice) of Lenzin oil is mixed with the sweetness of taste orange in preceding taste and is distributed therewith.
9. passive sleeping composition according to claim 4, which is characterized in that the pure essential oil packet of the formula of passive sleeping
Include limonene, linalool and bergamio.
10. the passive sleeping composition as described in claim 1-9 is any is reducing the application in mobility.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910035424.4A CN109602805A (en) | 2019-01-15 | 2019-01-15 | Passive sleeping composition and its application |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910035424.4A CN109602805A (en) | 2019-01-15 | 2019-01-15 | Passive sleeping composition and its application |
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| CN201910035424.4A Pending CN109602805A (en) | 2019-01-15 | 2019-01-15 | Passive sleeping composition and its application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112168885A (en) * | 2020-09-24 | 2021-01-05 | 吾悦堂教育科技(北京)有限公司 | Compound essential oil for treating insomnia |
-
2019
- 2019-01-15 CN CN201910035424.4A patent/CN109602805A/en active Pending
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| WELLHEAD健身: "妙梵芳疗 不同情绪引起的不同失眠", 《HTTPS://WWW.SOHU.COM/A/214836658_774666》 * |
| 柔辰健康: "芳疗师教你如何改善失眠问题？终结失眠的三处方！", 《HTTPS://WWW.SOHU.COM/A/245897910_100106319》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112168885A (en) * | 2020-09-24 | 2021-01-05 | 吾悦堂教育科技(北京)有限公司 | Compound essential oil for treating insomnia |
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| PB01 | Publication | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: Room 1511, Huajia Plaza, Hubei Road, Dongmen Street, Luohu District, Shenzhen City, Guangdong Province Applicant after: Shenzhen Chunrui Science and Technology Development Co., Ltd. Address before: Room 1511, Huajia Plaza, Hubei Road, Dongmen Street, Luohu District, Shenzhen City, Guangdong Province Applicant before: Shenzhen Chun Rui Trade Co., Ltd. |
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| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20190412 |