CN104800728A - External composite oil for rheumatoid arthritis and preparation method thereof - Google Patents
External composite oil for rheumatoid arthritis and preparation method thereof Download PDFInfo
- Publication number
- CN104800728A CN104800728A CN201510265939.5A CN201510265939A CN104800728A CN 104800728 A CN104800728 A CN 104800728A CN 201510265939 A CN201510265939 A CN 201510265939A CN 104800728 A CN104800728 A CN 104800728A
- Authority
- CN
- China
- Prior art keywords
- parts
- rheumatoid arthritis
- weight
- herba
- composite oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to external composite oil for rheumatoid arthritis. The external composite oil is prepared by adopting the following raw materials in parts by weight: 6 to 8 parts of saruma henryi, 6 to 8 parts of seeds of bird rape, 20 to 23 parts of radix tinosporae, 18 to 20 parts of carissa spinarum, 12 to 15 parts of anredera cordifolia, 12 to 15 parts of sharpleaf galangal fruit, 15 to 18 parts of youngia japonica, 3 to 4 parts of phellinus igniarius and 30 to 35 parts of grape seed oil. Different Chinese herbs are compatible with one another, so that an effect for promoting blood circulation, removing stasis, removing the swelling and alleviating the pain can be realized, the synergistic effect is remarkable, when the external composite oil is used as an external drug, active ingredients can conveniently permeate the skin to rapidly enter a pain position; the effect for treating the rheumatoid arthiritis is remarkable.
Description
Technical field
The invention belongs to field of medicaments, be specially a kind of external compound oil for rheumatoid arthritis and preparation method thereof.
Background technology
The cause of disease of rheumatoid arthritis is very not clear so far, mostly thinks that it is human autoimmune's property disease at present, also can be considered a kind of chronic syndrome, show as the nonspecific inflammation in joint, periphery.Now diseased joints and surrounding tissue thereof present Progressive symmetric erythrokeratodermia destruction, and cause damaged joints generating function obstacle.The sickness rate women of rheumatoid arthritis is higher than male, and women is 2 ~ 3 times of male; The sickness rate of American-European countries is apparently higher than compatriots.
The clinical treatment of rheumatoid arthritis generally comprises Drug therapy, surgical intervention and Psychological rehabilitation therapy etc.Conventional clinical treatment medicine is divided into four large classes: NSAID (non-steroidal anti-inflammatory drug), antirheumatic, glucocorticoid and other drug.Along with improving constantly of being familiar with primary disease, propose the pattern for the treatment of rheumatoid arthritis abroad: comprise pyramid pattern, wave pattern, pattern of topping bar and pattern of getting out of a predicament or an embarrassing situation.First pyramid pattern selects aspirin or other NSAIDs, repeatedly selects multiple NSAIDs, just selects golden preparation, penicillamine etc. to change the state of an illness antirheumatic time invalid; Wave pattern, i.e. zig-zag pattern, based on a kind of medicine, state of an illness activity or add when increasing the weight of and use other medicines, recovers basis again and treats, used by multiple chronic effect drug cycles like this after stable disease; To top bar pattern, i.e. Grading treatment pattern, advocate to be divided into gently by rheumatoid arthritis feelings severity, in, heavy after carry out corresponding therapeutic alliance; Get out of a predicament or an embarrassing situation pattern, advocate namely to use multi-medicament therapeutic alliance at the beginning, early application improves state of an illness medicine, once symptom management, withdrawal gradually, finally maintains with the medicine that a kind of side effect is little.
Summary of the invention
The object of this invention is to provide a kind of external compound oil for rheumatoid arthritis and preparation method thereof.
The present invention is used for the external compound oil of rheumatoid arthritis; Be made up of the crude drug of following parts by weight: Herba Asari 6 ~ 8 parts, Semen Brassicae Campestris 6 ~ 8 parts, 20 ~ 23 parts, golden lion rattan, thorn youth fruit 18 ~ 20 parts, Bulbilus boussingaultiae pseudobaselloidis 12 ~ 15 parts, Fructus Alpiniae Oxyphyllae 12 ~ 15 parts, Herba youngiae japonicae 15 ~ 18 parts, Phellinus igniarius (L. ex Fr.) Quel. 3 ~ 4 parts, Oleum Vitis viniferae 30 ~ 35 parts.
As optimization; this is used for the external compound oil of rheumatoid arthritis, is to be made up of the crude drug of following parts by weight: Herba Asari 7 parts, Semen Brassicae Campestris 7 parts, 22 parts, golden lion rattan, thorn youth fruit 19 parts, Bulbilus boussingaultiae pseudobaselloidis 13 parts, Fructus Alpiniae Oxyphyllae 13 parts, Herba youngiae japonicae 16 parts, Phellinus igniarius (L. ex Fr.) Quel. 3 parts, Oleum Vitis viniferae 33 parts.
Prepare this method for the external compound oil of rheumatoid arthritis, comprise the following steps:
A, the Herba Asari of described parts by weight, Semen Brassicae Campestris, golden lion rattan, thorn youth fruit, Bulbilus boussingaultiae pseudobaselloidis, Fructus Alpiniae Oxyphyllae, Herba youngiae japonicae are pulverized after mixing, by solid-liquid ratio 1:9, add 70% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merging backflow; Be condensed into the extractum that relative density is 1.25 ~ 1.32 (35 DEG C);
B, the Phellinus igniarius (L. ex Fr.) Quel. of described parts by weight is made 600 object powder, then with the Oleum Vitis viniferae of described parts by weight, at 85 ~ 90 DEG C, stir 2 ~ 3 hours;
C, by the extractum in step a, mixture mixing and stirring in step b.
The present invention is used in the external compound oil prescription of rheumatoid arthritis, Herba Asari wind and heat eliminating, pain relieving, promoting blood circulation and detoxication; Headche due to wind-cold, toothache, breathes with cough, and heatstroke is suffered from abdominal pain, dysentery, acute gastroenteritis, Fengshi Guanjie pain, traumatic injury; Venom is controlled in external.Semen Brassicae Campestris blood circulation promoting and blood stasis dispelling; Dispersing swelling and dissipating binds; Loosening bowel to relieve constipation; Main prolonged lochia; Abdominal pain due to blood stasis; Dysmenorrhea; Discharging fresh blood stool; Dysentery; Fengshi Guanjie swells and ache; Carbuncle erysipelas; Acute mastitis; Constipation; Adhesive ileus.Gold lion rattan heat-clearing and toxic substances removing, convergence analgesia; For heatstroke stomachache, stomachache, stomachache dysentery, rheumatic arthritis, venom, hypertension, skin eczema.Thorn youth fruit heat-clearing and toxic substances removing; Anti-inflammatory analgetic; Main icterohepatitis; Stomachache; Rheumatic arthritis; Acute conjunctivitis; Pharyngolaryngitis; Periodontitis; Lymphadenitis.Bulbilus boussingaultiae pseudobaselloidis replenishing kidney, strengthening waist; Dissipating blood stasis for subsidence of swelling; Main waist knee joint arthralgia pain; Weak after being ill; Traumatic injury; Fracture.Fructus Alpiniae Oxyphyllae is warming spleen and stopping diarrha takes the photograph saliva; Warming the kidney reducing urination controlling nocturnal emission with astringent drugs; Main Deficiency and coldness of spleen and stomach; Vomiting; Have loose bowels; Coldly in abdomen to educate; The many salivas of mouth; Enuresis due to deficiency of the kidney; Frequent micturition; Seminal emission; Nebulousurine.Herba youngiae japonicae anti-inflammation; Control furuncle, mastitis, tonsillitis, urinary tract infection, leucorrhea, conjunctivitis, rheumatic arthritis.Phellinus igniarius (L. ex Fr.) Quel. profit the five internal organs, softening the hard mass, toxin expelling, hemostasis, invigorates blood circulation, stomach function regulating antidiarrheal; Cure mainly gonorrhea, bleeding not during menses, lump in the abdomen, hypochondrium fluid retention, diarrhea due to hypofunction of the spleen.Semen Vitis viniferae free radical resisting, reduction blood fat, protection skin, protection brain, antiallergic, protection blood vessel, radioprotective, protective tissue, protection eyes; Effective ingredient procyanidin is high-efficiency antioxidant agent, is the most effective free radical scavenger, has very strong activity in vivo; The initiation potential of the diseases such as heart disease, cancer, senilism, arthritis can be reduced; Strengthen blood vessel wall resistance; Reduce the initiation potential of diabetes; Strengthen skin elasticity and smoothness, prevention sunray is to effects such as the radiation damagies of skin.
All medicine compatibilities, blood circulation promoting and blood stasis dispelling, anti-inflammatory analgetic, each composition synergism give prominence to, as external preparation easily and effectively composition transdermal enter ailing position fast; Do not damage hepatic and renal function; Be used for the treatment of rheumatoid arthritis effect very remarkable.
Pertinent clinical data is as follows: physical data: patient with rheumatoid arthritis 296 example.Wherein male 97 example, women 199 example, 26 years old ~ 75 years old age, 48 years old mean age.The course of disease 2 months ~ 18 years, average course of disease 4 years.Be divided into 2 groups at random, often organize 148 examples.
Diagnosis basis: Western medicine diagnose was both diagnosed according to American Rheumatism Association's revision diagnosis of rheumatoid arthritis standard in 1987.Diagnostic criteria comprises: (1) deadlock in morning is 1h (course of disease >=6 week) at least; (2) 3 or 3 delete with upper joint; (3) wrist, metacarpophalangeal joints or near-end refer to ask swollen joint; (4) symmetry swollen joint; (5) subcutaneous nodule; (6) hands x line sheet changes; (7) rheumatoid factor positive (titre >1:32).All possess above 4 standards, and patient with connection portion symptom for main person examines as rheumatoid arthritis.
Tcm diagnosis is ridiculed according to the diagnosis basis of arthromyodynia in disease of tcm Standardization of diagnosis and curative effect and is diagnosed.Patients is joint swelling and pain, localized pain, and morning, stiff joint stuffiness, met then pain play of trembling with fear, and local fear of cold is afraid of cold, thin white fur of tongue, and floating and tense pulse or heavy tight person are diagnosed as wind-cold-damp retention type arthromyodynia.Door bolt.Possess above condition, and patient with knee symptom for main person examines as rheumatoid gonarthritis.Inclusive criteria: simultaneously meet Western medicine diagnose standard and tcm diagnosis standard.
Therapeutic Method: matched group, simple oral ZHENGQINGFENGTONGNING PIAN, each 2, day 3 times.Treatment group, adopts the external compound oil for rheumatoid arthritis in the embodiment of the present invention, is applied to affected part, and massage is even, four times a day, observe the curative effect after month.
Efficacy evaluation: efficacy evaluation is evaluated according to the efficacy assessment standard of arthromyodynia in disease of tcm Standardization of diagnosis and curative effect.(1) clinical cure: arthralgia, swelling disappear, and movable function is normal, and lab testing is normal; (2) take a turn for the better: arthralgia, swelling alleviate, movable function takes a turn for the better, and lab testing is improved; (3) do not heal: arthralgia, swelling and lab testing are unchanged.Two groups of patient's efficacy results are in table 1.
Detailed description of the invention
The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.
Embodiment 1, a, by Herba Asari 70 grams, Semen Brassicae Campestris 70 grams, 220 grams, golden lion rattan, thorn youth fruit 190 grams, Bulbilus boussingaultiae pseudobaselloidis 130 grams, Fructus Alpiniae Oxyphyllae 130 grams, Herba youngiae japonicae 160 grams pulverize after mixing, by solid-liquid ratio 1:9, add 70% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merges backflow; Be condensed into the extractum that relative density is 1.25 ~ 1.32 (35 DEG C); B, Phellinus igniarius (L. ex Fr.) Quel. 30 is restrained into 600 object powder, then with Oleum Vitis viniferae 330 grams, at 85 ~ 90 DEG C, stir 2 ~ 3 hours; C, by the extractum in step a, the mixture in step b, sorbitanmonolaureate 1 gram of mixing and stirring.
Embodiment 2, a, by Herba Asari 60 grams, Semen Brassicae Campestris 60 grams, 200 grams, golden lion rattan, thorn youth fruit 180 grams, Bulbilus boussingaultiae pseudobaselloidis 120 grams, Fructus Alpiniae Oxyphyllae 120 grams, Herba youngiae japonicae 150 grams pulverize after mixing, by solid-liquid ratio 1:9, add 70% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merges backflow; Be condensed into the extractum that relative density is 1.25 ~ 1.32 (35 DEG C); B, Phellinus igniarius (L. ex Fr.) Quel. 30 is restrained into 600 object powder, then with Oleum Vitis viniferae 300 grams, at 85 ~ 90 DEG C, stir 2 ~ 3 hours; C, by the extractum in step a, mixture mixing and stirring in step b.
Embodiment 3, a, by Herba Asari 80 grams, Semen Brassicae Campestris 80 grams, 230 grams, golden lion rattan, thorn youth fruit 200 grams, Bulbilus boussingaultiae pseudobaselloidis 150 grams, Fructus Alpiniae Oxyphyllae 150 grams, Herba youngiae japonicae 180 grams pulverize after mixing, by solid-liquid ratio 1:9, add 70% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merges backflow; Be condensed into the extractum that relative density is 1.25 ~ 1.32 (35 DEG C); B, Phellinus igniarius (L. ex Fr.) Quel. 40 is restrained into 600 object powder, then with Oleum Vitis viniferae 350 grams, at 85 ~ 90 DEG C, stir 2 ~ 3 hours; C, by the extractum in step a, mixture mixing and stirring in step b.
Claims (3)
1. the external compound oil for rheumatoid arthritis; It is characterized in that being made up of the crude drug of following parts by weight: Herba Asari 6 ~ 8 parts, Semen Brassicae Campestris 6 ~ 8 parts, 20 ~ 23 parts, golden lion rattan, thorn youth fruit 18 ~ 20 parts, Bulbilus boussingaultiae pseudobaselloidis 12 ~ 15 parts, Fructus Alpiniae Oxyphyllae 12 ~ 15 parts, Herba youngiae japonicae 15 ~ 18 parts, Phellinus igniarius (L. ex Fr.) Quel. 3 ~ 4 parts, Oleum Vitis viniferae 30 ~ 35 parts.
2. the outer compound oil for rheumatoid arthritis according to claim 1, it is characterized in that being made up of the crude drug of following parts by weight: Herba Asari 7 parts, Semen Brassicae Campestris 7 parts, 22 parts, golden lion rattan, thorn youth fruit 19 parts, Bulbilus boussingaultiae pseudobaselloidis 13 parts, Fructus Alpiniae Oxyphyllae 13 parts, Herba youngiae japonicae 16 parts, Phellinus igniarius (L. ex Fr.) Quel. 3, Oleum Vitis viniferae 33 parts.
3. prepare the method for the external compound oil of rheumatoid arthritis described in claim 1, it is characterized in that comprising the following steps:
A, the Herba Asari of described parts by weight, Semen Brassicae Campestris, golden lion rattan, thorn youth fruit, Bulbilus boussingaultiae pseudobaselloidis, Fructus Alpiniae Oxyphyllae, Herba youngiae japonicae are pulverized after mixing, by solid-liquid ratio 1:9, add 70% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merging backflow; Be condensed into the extractum that relative density is 1.25 ~ 1.32 (35 DEG C);
B, the Phellinus igniarius (L. ex Fr.) Quel. of described parts by weight is made 600 object powder, then with the Oleum Vitis viniferae of described parts by weight, at 85 ~ 90 DEG C, stir 2 ~ 3 hours;
C, by the extractum in step a, mixture mixing and stirring in step b.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510265939.5A CN104800728A (en) | 2015-05-25 | 2015-05-25 | External composite oil for rheumatoid arthritis and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510265939.5A CN104800728A (en) | 2015-05-25 | 2015-05-25 | External composite oil for rheumatoid arthritis and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN104800728A true CN104800728A (en) | 2015-07-29 |
Family
ID=53686207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510265939.5A Pending CN104800728A (en) | 2015-05-25 | 2015-05-25 | External composite oil for rheumatoid arthritis and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104800728A (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1098309A (en) * | 1994-02-02 | 1995-02-08 | 李庆和 | The Chinese medicinal capsule of treatment rheumatoid arthritis |
JP2001097878A (en) * | 1999-09-03 | 2001-04-10 | Chinko Tei | Compositions for treating rheumatism and method for producing the same |
-
2015
- 2015-05-25 CN CN201510265939.5A patent/CN104800728A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1098309A (en) * | 1994-02-02 | 1995-02-08 | 李庆和 | The Chinese medicinal capsule of treatment rheumatoid arthritis |
JP2001097878A (en) * | 1999-09-03 | 2001-04-10 | Chinko Tei | Compositions for treating rheumatism and method for producing the same |
Non-Patent Citations (1)
Title |
---|
史文宇: "《骨伤疾病内外治法》", 30 April 2009 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN100998843A (en) | Medicinal composition for treating cholecystitis | |
CN102441081B (en) | Medicament for treating gout and its preparation method | |
CN1839941A (en) | Chinese prepared medicine for treating bone pain | |
CN101301343B (en) | Chinese medicine paste for promoting healing of bone fracture | |
CN107468768A (en) | A kind of Qiang's drug composition and application thereof | |
CN106860717A (en) | It is a kind of to treat infertile medicine | |
CN104800728A (en) | External composite oil for rheumatoid arthritis and preparation method thereof | |
CN101474329B (en) | Moschus skin recovery paste for treating damaged skin | |
CN108686102A (en) | A kind of Chinese medicine composition for treating gout | |
CN109350711A (en) | A kind of combined traditional Chinese medicine preparation that treating diabetes and preparation method | |
CN100536895C (en) | Formulaion in traditional chinese medical prescription for treating waist and neck hyperosteogeny | |
CN104840624A (en) | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof | |
CN113648349B (en) | A topical Chinese medicinal composition for preventing and treating rheumatism and pyretic arthralgia, and its preparation method | |
CN110893206B (en) | Externally applied medicine for treating rheumatic arthritis and preparation method thereof | |
CN106421534A (en) | Traditional Chinese medicinal composition for treating rheumatoid arthritis and preparation method thereof | |
CN105617214A (en) | Traditional Chinese medicine composition for treating scabies | |
CN106075272B (en) | Mongolian medicine for treating peptic ulcer and preparation method thereof | |
CN104906467A (en) | Traditional Chinese medicine composition for treating gout and preparation method | |
CN105148050A (en) | Traditional Chinese medicinal composition for treating kidney stone | |
CN1235629C (en) | Traditional Chinese medicine composition for treating choleithiasis | |
CN103070998B (en) | Externally-applied plaster for curing pain of rheumatic joints | |
CN110934949A (en) | Traditional Chinese medicine for treating hydrocephalus and hematoma after cerebral hemorrhage and preparation method thereof | |
CN103933278A (en) | Preparation method of Tibetan drug for treating gout disease | |
CN115006461A (en) | Traditional Chinese medicine composition for treating gout and preparation method and application thereof | |
CN103356825B (en) | Chinese medicine decoction for early treatment of bone and joint injury |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
EXSB | Decision made by sipo to initiate substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150729 |