CN104800684A - Traditional Chinese medicine composition for treating varicosity - Google Patents
Traditional Chinese medicine composition for treating varicosity Download PDFInfo
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- CN104800684A CN104800684A CN201510224254.6A CN201510224254A CN104800684A CN 104800684 A CN104800684 A CN 104800684A CN 201510224254 A CN201510224254 A CN 201510224254A CN 104800684 A CN104800684 A CN 104800684A
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Abstract
The invention provides a traditional Chinese medicine composition for treating varicosity. The traditional Chinese medicine composition is made from the following raw materials: 60 parts of astragali radix, 15 parts of tuber fleeceflower stems, 15 parts of dragon bones and 10 parts of elecampane. The traditional Chinese medicine composition can treat the varicosity.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to one and be used for the treatment of cirsoid Chinese medicine composition and its preparation method and application.
Background technology
Varicosis refers to that the vein caused is tortuous, expansion due to factors such as blood stasis, vein tube wall weaknesses.All can there is varicose in the vein at the multiple position of health, such as hemorrhoid are exactly a kind of varicosis in fact, clinical visible esophagus fundus ventricularis varication, varicocele and abdominal wall varicosis etc. in addition.The position that varicosis the most often occurs is at lower limb.It is emphasized that varicosis itself may be the secondary manifestation of other pathological changes, as inaccessible in caval vein etc., answer positive treatment protopathy.The traditional Chinese medical science thinks that lower limb are chronic for ecthyma, and how by standing for a long time or excessively bearing a heavy burden, and cause shank flaccidity of muscles and vessels, blue veins appears, and the stasis of blood stops venation, heat-transformation for a long time, or skin of leg breakage contamination, and damp invasion of lower energizer forms, and the open sore part is prolonged not to heal.For this reason, be bursting to develop and manyly treat the needs that cirsoid medicine meets clinical treatment safely and effectively.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of varicose vein disease.In order to reach this object, adopt following technical scheme:
Technical scheme: one is used for the treatment of cirsoid Chinese medicine composition, active component contained by it is extracted by following weight crude drug and is prepared from: Radix Astragali 60 parts, Caulis Polygoni Multiflori 15 parts, Os Draconis (calcined) 15 parts, the Radix Aucklandiae 10 parts, Fructus Setariae Germinatus (parched) 10 parts, Fructus Hordei Germinatus (parched) 10 parts, Radix Ophiopogonis 10 parts, Fructus Schisandrae Chinensis 5 parts, Radix Codonopsis 10 parts, Herba Epimedii 10 parts, Fructus Trichosanthis 10 parts, Radix Paeoniae Rubra 10 parts, Rhizoma Chuanxiong 10 parts, Radix Angelicae Sinensis 10 parts, the Rhizoma Anemarrhenae 10 parts, Pheretima 10 parts, 10 parts, Semen Persicae, 10 parts, Flos Carthami, Radix Puerariae 30 parts, Concha Ostreae 30 parts, Herba Plantaginis 10 parts, Herba Siegesbeckiae 30 parts, Radix Achyranthis Bidentatae 15 parts, Herba Taxilli 15 parts, Radix Clematidis 20 parts, Rhizoma Et Radix Notopterygii 10 parts, Radix Angelicae Pubescentis 10 parts, the Cortex Eucommiae 10 parts, Radix Scutellariae 10 parts, 5 parts, Radix Glycyrrhizae.
Describedly be used for the treatment of cirsoid Chinese medicine composition, dosage form is pharmaceutically acceptable granule, tablet, capsule.
Describedly be used for the treatment of cirsoid Chinese medicine composition, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
Describedly be used for the treatment of the application of cirsoid Chinese medicine composition in preparation treatment varicosis medicine.
Above-mentioned Chinese medicine is pharmacopeia kind.
Beneficial effect: Radix Astragali of the present invention, Caulis Polygoni Multiflori, Os Draconis (calcined), the Radix Aucklandiae, Fructus Setariae Germinatus (parched), Fructus Hordei Germinatus (parched), Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Codonopsis, Herba Epimedii, Fructus Trichosanthis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Rhizoma Anemarrhenae, Pheretima, Semen Persicae, Flos Carthami, Radix Puerariae, Concha Ostreae, Herba Plantaginis, Herba Siegesbeckiae, Radix Achyranthis Bidentatae, Herba Taxilli, Radix Clematidis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, the Cortex Eucommiae, Radix Scutellariae, Radix Glycyrrhizae, heat-clearing and toxic substances removing, circulation of qi promoting treating blood disorders, blood circulation promoting and blood stasis dispelling, treatment varicosis successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Radix Astragali 60g, Caulis Polygoni Multiflori 15g, Os Draconis (calcined) 15g, Radix Aucklandiae 10g, Fructus Setariae Germinatus (parched) 10g, Fructus Hordei Germinatus (parched) 10g, Radix Ophiopogonis 10g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 10g, Herba Epimedii 10g, Fructus Trichosanthis 10g, Radix Paeoniae Rubra 10g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 10g, Rhizoma Anemarrhenae 10g, Pheretima 10g, Semen Persicae 10g, Flos Carthami 10g, Radix Puerariae 30g, Concha Ostreae 30g, Herba Plantaginis 10g, Herba Siegesbeckiae 30g, Radix Achyranthis Bidentatae 15g, Herba Taxilli 15g, Radix Clematidis 20g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Cortex Eucommiae 10g, Radix Scutellariae 10g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, and atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Radix Astragali 60g, Caulis Polygoni Multiflori 15g, Os Draconis (calcined) 15g, Radix Aucklandiae 10g, Fructus Setariae Germinatus (parched) 10g, Fructus Hordei Germinatus (parched) 10g, Radix Ophiopogonis 10g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 10g, Herba Epimedii 10g, Fructus Trichosanthis 10g, Radix Paeoniae Rubra 10g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 10g, Rhizoma Anemarrhenae 10g, Pheretima 10g, Semen Persicae 10g, Flos Carthami 10g, Radix Puerariae 30g, Concha Ostreae 30g, Herba Plantaginis 10g, Herba Siegesbeckiae 30g, Radix Achyranthis Bidentatae 15g, Herba Taxilli 15g, Radix Clematidis 20g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Cortex Eucommiae 10g, Radix Scutellariae 10g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, adds dextrin 50g, granulates, tabletting, makes tablet.
3, the preparation of capsule embodiment: get Radix Astragali 60g, Caulis Polygoni Multiflori 15g, Os Draconis (calcined) 15g, Radix Aucklandiae 10g, Fructus Setariae Germinatus (parched) 10g, Fructus Hordei Germinatus (parched) 10g, Radix Ophiopogonis 10g, Fructus Schisandrae Chinensis 5g, Radix Codonopsis 10g, Herba Epimedii 10g, Fructus Trichosanthis 10g, Radix Paeoniae Rubra 10g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 10g, Rhizoma Anemarrhenae 10g, Pheretima 10g, Semen Persicae 10g, Flos Carthami 10g, Radix Puerariae 30g, Concha Ostreae 30g, Herba Plantaginis 10g, Herba Siegesbeckiae 30g, Radix Achyranthis Bidentatae 15g, Herba Taxilli 15g, Radix Clematidis 20g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Cortex Eucommiae 10g, Radix Scutellariae 10g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, adds starch 50g, granulates, fill, makes capsule.
4, traditional Chinese medicine composition for treating varicosis of the present invention clinical research
4.1 general data: this Chinese medicine composition is applied to clinical observation varicosis case 80 example, 57 ~ 79 years old age.The shortest person of the course of disease 5 years, most elder reaches 10 years, average 8.6 years.
4.2 diagnostic criterias: comparatively common with shank in shank (inner side).Local is from the beginning of pain after often first itching, and color is red, rotten to the corn, transfers ulcer to rapidly.Ulcer differs in size, in greyish white or kermesinus, and surface or with yellow pus tongue, pus is dirty smelly unpleasant.Sick ulcer edge is thickening raised for a long time, surrounding color of the leather darkness, unrestrained swollen or with eczema, easy recurrent exerbation after closing up.Be more common in the patient that lower limb suffer from flaccidity of muscles and vessels (varicosis).
4.3 syndrome-classification
4.3.1 damp invasion of lower energizer: skin ulcer complexion is dark, or upper attached pus tongue, pus is contaminated, dirty smelly unpleasant, and surrounding is unrestrained swollen scorching hot.With eczema, do during sufferings, very have fever with aversion to cold.Yellowish fur, rapid pulse.
4.3.2 insufficiency of the spleen leading to overabundance of dampness: with the passing of time, skin ulcer complexion is dark for the course of disease, and yellow fluid is contaminated, suffering limb edema, receives food abdominal distention, loose stool, shallow complexion.Light red tongue, tongue is greasy in vain, and deep pulse is unable.
4.3.3 blood stasis due to qi deficiency: fester year in year out, slough is de-, and play white webbing, skin ulcer face yellowish pink is pale, and surrounding colour of skin darkness, stiff wood is hard.Light purplish tongue, tongue is greasy in vain, thready and hesitant pulse.
4.4 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within 30 days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule 30 days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.5 criterions of therapeutical effect: clinical recovery: ulcer healing.Take a turn for the better: ulcer reduces.Invalid: ulcer skin ulcer face has no and reduces or have expansion.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 40 | 10 | 24 | 6 | 85 |
| Blank group | 40 | 1 | 2 | 37 | 7.5 |
Visible the present invention has good therapeutic effect to varicosis, and toxic and side effects does not occur treatments period.
4.6 model cases:
Lee, man, 62 years old, medial leg ulcer, in kermesinus, surface was with yellow pus tongue, and pus is dirty smelly unpleasant, and surrounding is unrestrained swollen scorching hot.With eczema, do during sufferings, very have fever with aversion to cold.Yellowish fur, rapid pulse, is diagnosed as damp invasion of lower energizer, takes above-mentioned process for producing granula and prepares clinical sample, and specification is 10 grams every bag, within 30 days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum, ulcer healing after 2 months.
Claims (4)
1. one kind is used for the treatment of cirsoid Chinese medicine composition, it is characterized in that, active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Radix Astragali 60 parts, Caulis Polygoni Multiflori 15 parts, Os Draconis (calcined) 15 parts, the Radix Aucklandiae 10 parts, Fructus Setariae Germinatus (parched) 10 parts, Fructus Hordei Germinatus (parched) 10 parts, Radix Ophiopogonis 10 parts, Fructus Schisandrae Chinensis 5 parts, Radix Codonopsis 10 parts, Herba Epimedii 10 parts, Fructus Trichosanthis 10 parts, Radix Paeoniae Rubra 10 parts, Rhizoma Chuanxiong 10 parts, Radix Angelicae Sinensis 10 parts, the Rhizoma Anemarrhenae 10 parts, Pheretima 10 parts, 10 parts, Semen Persicae, 10 parts, Flos Carthami, Radix Puerariae 30 parts, Concha Ostreae 30 parts, Herba Plantaginis 10 parts, Herba Siegesbeckiae 30 parts, Radix Achyranthis Bidentatae 15 parts, Herba Taxilli 15 parts, Radix Clematidis 20 parts, Rhizoma Et Radix Notopterygii 10 parts, Radix Angelicae Pubescentis 10 parts, the Cortex Eucommiae 10 parts, Radix Scutellariae 10 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of cirsoid Chinese medicine composition as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of cirsoid Chinese medicine composition as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of cirsoid Chinese medicine composition in treatment varicosis medicine according to claim 1.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177135A (en) * | 2016-08-10 | 2016-12-07 | 徐柳 | One is used for treating cirsoid medicine and preparation method thereof, application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485867A (en) * | 2009-03-02 | 2009-07-22 | 安士强 | Chinese medicinal composition for treating varix and preparation method thereof |
| CA2790906A1 (en) * | 2009-02-25 | 2010-09-02 | Byzmed Llc | Composition and methods for clotting blood |
| CN104367765A (en) * | 2014-11-27 | 2015-02-25 | 李洋 | Traditional Chinese medicinal composition for treating depression as well as preparation method and application thereof |
-
2015
- 2015-04-30 CN CN201510224254.6A patent/CN104800684A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2790906A1 (en) * | 2009-02-25 | 2010-09-02 | Byzmed Llc | Composition and methods for clotting blood |
| CN101485867A (en) * | 2009-03-02 | 2009-07-22 | 安士强 | Chinese medicinal composition for treating varix and preparation method thereof |
| CN104367765A (en) * | 2014-11-27 | 2015-02-25 | 李洋 | Traditional Chinese medicinal composition for treating depression as well as preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 孙志海: "浅谈补阳还五汤的临床应用", 《实用中医内科杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177135A (en) * | 2016-08-10 | 2016-12-07 | 徐柳 | One is used for treating cirsoid medicine and preparation method thereof, application |
| CN106177135B (en) * | 2016-08-10 | 2020-04-17 | 徐柳 | Medicine for treating varicosity and preparation method and application thereof |
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