CN104800530A - Traditional Chinese medicine composition for treating oral ulcer and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating oral ulcer and preparation method of traditional Chinese medicine composition Download PDFInfo
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- CN104800530A CN104800530A CN201510207874.9A CN201510207874A CN104800530A CN 104800530 A CN104800530 A CN 104800530A CN 201510207874 A CN201510207874 A CN 201510207874A CN 104800530 A CN104800530 A CN 104800530A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating oral ulcer. The traditional Chinese medicine composition comprises the following raw materials: radix isatidis, forsythia suspensa, herba artemisiae scopariae, taraxacum mongolicum, fried immature orange fruits, plaster stone, scutellaria baicalensis, honeysuckle stems, carbonized fructus gardeniae, rhizoma anemarrhenae, radix rehmanniae, platycodon roots and radix glycyrrhizae. The preparation method comprises the following steps: weighing desired raw materials of the components, cleaning the weighed raw materials, putting the cleaned raw materials into a decoction vessel, adding water, soaking the raw materials in the decoction vessel for 30-40 minutes, performing ignition, decocting the medicinal materials in the decoction vessel with strong fire until boiling, and then decocting with soft fire for totally 30-40 minutes; stopping heating the decoction vessel, performing filtration, and obtaining filtrate so as to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition disclosed by the invention aims to be capable of efficiently treating refractory multiple oral ulcer, besides, side effects of medication can be alleviated, and harm to human bodies in the medication process is alleviated; the invention further provides the preparation method, so that the medicine effect of the traditional Chinese medicine composition is furthest improved, and besides, the preparation method is simpler and easier to operate.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, particularly a kind of Chinese medicine composition for the treatment of oral ulcer and preparation method thereof.
Background technology
Oral ulcer is a kind of common disease of cari oris mucosa, and also known as aphtha, during outbreak, pain clearly, can untreated and spontaneous recovery.Also the recurrent exerbation had, is called intractable, multiple oral ulcer, causes very large impact to the work of patient and life.The concrete pathogenic factor of intractable, multiple oral ulcer there is no final conclusion so far, but its generation is relevant to many factors, as cellular immune function reduces; The digestive system disease such as abdominal distention, diarrhoea or constipation; Hormonal change; The Nervous and Mental Factors such as psychentonia, sleep state are not good; Lack other factors such as trace element zinc, ferrum, folic acid, vitamin B l2, heredity.The product in existing market has the sprayable medicine of powdery; Graininess Chinese medicine pill for oral administration; Pasting shape medicine has " meaning can be pasted "; Also has dietetic therapy.These have certain effect to treatment, but all respectively have it to lay particular stress on and weak point.Though spray directly can be applied to affected part, the comparatively pill that takes effect is fast, but medicine is easily along with saliva is swallowed, and drug effect is had a greatly reduced quality; Granular pill is required to be master in regulating, and takes effect slow; Paste shape product and go operation as " meaning can be pasted " needs with hands, easy Carried bacteria causes wound to infect further.
The information being disclosed in this background technology part is only intended to increase the understanding to general background of the present invention, and should not be regarded as admitting or imply in any form that this information structure has been prior art that persons skilled in the art are known.
Summary of the invention
Of the present invention for technical problem of the prior art, invent a kind of Chinese medicine composition being used for the treatment of ulcerative colitis, the side effect alleviating medication while being intended to efficiently to treat intractable, multiple oral ulcer with in medication process to the harm of human body.
Another object of the present invention is to provide a kind of preparation method of Chinese medicine composition being used for the treatment of intractable, multiple oral ulcer, thus improves the drug effect of this Chinese medicine composition to greatest extent, meanwhile, makes preparation method more succinct, easy to operate.
For achieving the above object, technical scheme provided by the invention is as follows:
Be used for the treatment of a Chinese medicine composition for oral ulcer, according to ratio of weight and number, be made up of following component raw material: Radix Isatidis 9-12 part, Fructus Forsythiae 9-12 part, Herba Artemisiae Scopariae 6-9 part, Herba Taraxaci 10-15 part, Fructus Aurantii Immaturus (parched) 6-9 part, Gypsum Fibrosum 20-30 part, Radix Scutellariae 9-12 part, Caulis Lonicerae 9-15 part, classed FRUCTUS GARDENIAE 9-12 part, Rhizoma Anemarrhenae 9-12 part, Radix Rehmanniae 9-15 part, Radix Platycodonis 6-9 part, Radix Glycyrrhizae 5-10 part.
Preferably, Radix Isatidis 12 parts, Fructus Forsythiae 10 parts, Herba Artemisiae Scopariae 6 parts, Herba Taraxaci 12 parts, Fructus Aurantii Immaturus (parched) 6 parts, Gypsum Fibrosum 30 parts, Radix Scutellariae 10 parts, Caulis Lonicerae 12 parts, classed FRUCTUS GARDENIAE 10 parts, the Rhizoma Anemarrhenae 10 parts, 15 parts, the Radix Rehmanniae, Radix Platycodonis 6 parts, Radix Glycyrrhizae 6 parts.
Be used for the treatment of a preparation method for the Chinese medicine composition of oral ulcer as mentioned above, comprise following operating procedure:
(1) according to ratio of weight and number, take required each component raw material, clean, put into decoction vessel;
(2) add water in decoction vessel in step (1), soak 30 ~ 40min, open fire, with high heat by the extremely boiling of decocting for Chinese herbal medicine in decoction vessel, then use slow fire boiling instead, decocting total time is 30 ~ 40min, Guan Huo, filters, gets filtrate and get final product.
Preferably, the Chinese medicine putting into decoction vessel shakeouts in (2) by step, adds water as exceeding the water yield shakeouing rear Chinese medicine plane 3 ~ 4cm.
Preferably, be filtered in step (2) and get 3 ~ 4 layers of gauze and make filter cloth and filter.
It is potion that said method prepares gained Chinese medicine composition, and the instructions of taking of Chinese medicine of the present invention is: potion on the one, and potion divides to be taken for twice sooner or later, within 7 days, is a course for the treatment of.Treatments period should be taken food light, digestible food, keeps happy, notes striking a proper balance between work and rest, other Chinese medicine and western medicine of stopping using.
The present invention selects Radix Isatidis, Fructus Forsythiae, Herba Artemisiae Scopariae, Herba Taraxaci, Fructus Aurantii Immaturus (parched), Gypsum Fibrosum, Radix Scutellariae, Caulis Lonicerae, classed FRUCTUS GARDENIAE, the Rhizoma Anemarrhenae, the Radix Rehmanniae, Radix Platycodonis, and Radix Glycyrrhizae combines, and is made by these drug regimens effect between each medicine produce synergism.
In the middle of Chinese medicine composition of the present invention, the detumescence of Radix Isatidis heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving; Fructus Forsythiae has broad-spectrum antibacterial action, has very strong inhibitory action to staphylococcus aureus, Hayes dysentery bacterium; Herba Artemisiae Scopariae function of gallbladder promoting, liver function protecting, antipyretic, antiinflammatory, blood fat reducing, blood pressure lowering; Herba Taraxaci heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, antiinflammatory, removing heat from blood, diuresis, function of gallbladder promoting; Fructus Aurantii Immaturus (parched) dispelling the stagnated QI removing food stagnancy, reduce phlegm except painful abdominal mass; Gypsum Fibrosum clearing away heat-fire, relieving restlessness quench the thirst, restrain granulation promoting; Radix Scutellariae heat clearing and damp drying, removing heat from blood is antiabortive, removing toxic substances; Caulis Lonicerae heat-clearing and toxic substances removing, dredging collateral; Classed FRUCTUS GARDENIAE pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Rhizoma Anemarrhenae heat clearing away reducing internal heat; Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, to promote the production of body fluid; Radix Platycodonis energy expelling phlegm for arresting cough, and have lung qi dispersing, evacuation of pus effect; Radix Glycyrrhizae cures mainly laryngopharynx swelling and pain, cellulitis skin infection, gastrointestinal ulceration and solution poison of drug, alimentary toxicosis etc.All medicines and use in side, play effect of heat-clearing and toxic substances removing, antiinflammatory removing heat from blood, removing the necrotic tissue and promoting granulation altogether, jointly reaches the object for the treatment of refractory multiple oral ulcer.
Compared with prior art, the present invention has following beneficial effect:
Above-mentioned various raw material of Chinese medicine carries out reasonably combined by the present invention, the proportioning of each component raw material adopted makes each raw material serve good synergism, namely its effect given play to by often kind of Chinese medicine, treatment promulgated by the State Council excellent, further, preparation technology of the present invention is simple, makes each component effective ingredient be extracted more in preparation process, play the curative effect of compositions better, additionally reduce dose simultaneously; And have no adverse reaction, safety is very high; The property of medicine relaxes, and can not cause drug dependence.
Detailed description of the invention
Be described in detail below in conjunction with detailed description of the invention, but be to be understood that protection scope of the present invention not by the restriction of detailed description of the invention.
Embodiment 1
In units of g, take following component raw material: Radix Isatidis 12 parts, Fructus Forsythiae 10 parts, Herba Artemisiae Scopariae 6 parts, Herba Taraxaci 12 parts, Fructus Aurantii Immaturus (parched) 6 parts, Gypsum Fibrosum 30 parts, Radix Scutellariae 10 parts, Caulis Lonicerae 12 parts, classed FRUCTUS GARDENIAE 10 parts, the Rhizoma Anemarrhenae 10 parts, 15 parts, the Radix Rehmanniae, Radix Platycodonis 6 parts, Radix Glycyrrhizae 6 parts, cleans each component medical herbs clear water taken, put into medicine decocting tank to shakeout, add pure water, adding pure water is the amount exceeding the Chinese medicine plane 4cm after shakeouing in medicine decocting tank; Soak 30min, open fire, with high heat by the extremely boiling of decocting for Chinese herbal medicine in medicine decocting tank, then use slow fire boiling instead at once, decocting total time is 40min, Guan Huo, filters, get filtrate and get final product with the filter cloth that 4 layers of gauze are made.
Embodiment 2
In units of g, take following component raw material: Radix Isatidis 9 parts, Fructus Forsythiae 9 parts, Herba Artemisiae Scopariae 8 parts, Herba Taraxaci 10 parts, Fructus Aurantii Immaturus (parched) 7 parts, Gypsum Fibrosum 20 parts, Radix Scutellariae 9 parts, Caulis Lonicerae 9 parts, classed FRUCTUS GARDENIAE 9 parts, the Rhizoma Anemarrhenae 9 parts, 9 parts, the Radix Rehmanniae, Radix Platycodonis 8 parts, Radix Glycyrrhizae 5 parts, cleans each component medical herbs clear water taken, put into medicine decocting tank to shakeout, add pure water, adding pure water is the amount exceeding the Chinese medicine plane 3cm after shakeouing in medicine decocting tank; Soak 35min, open fire, with high heat by the extremely boiling of decocting for Chinese herbal medicine in medicine decocting tank, then use slow fire boiling instead at once, decocting total time is 35min, Guan Huo, filters, get filtrate and get final product with the filter cloth that 3 layers of gauze are made.
Embodiment 3
In units of g, take following component raw material: Radix Isatidis 11 parts, Fructus Forsythiae 12 parts, Herba Artemisiae Scopariae 9 parts, Herba Taraxaci 15 parts, Fructus Aurantii Immaturus (parched) 9 parts, Gypsum Fibrosum 25 parts, Radix Scutellariae 12 parts, Caulis Lonicerae 15 parts, classed FRUCTUS GARDENIAE 12 parts, the Rhizoma Anemarrhenae 12 parts, 12 parts, the Radix Rehmanniae, Radix Platycodonis 9 parts, Radix Glycyrrhizae 10 parts, cleans each component medical herbs clear water taken, put into medicine decocting tank to shakeout, add pure water, adding pure water is the amount exceeding the Chinese medicine plane 3cm after shakeouing in medicine decocting tank; Soak 40min, open fire, with high heat by the extremely boiling of decocting for Chinese herbal medicine in medicine decocting tank, then use slow fire boiling instead at once, decocting total time is 30min, Guan Huo, filters, get filtrate and get final product with the filter cloth that 4 layers of gauze are made.
Curative effect is investigated
For checking therapeutic effect of the present invention, choosing 50 routine intractables, multiple oral ulcer person gives the traditional Chinese medicine composition for treating that the above embodiment of the present invention prepares gained.Wherein male 28 example, women 22 example, age 26-56 year, 36 years old mean age.The course of disease is person 2 example within 3 years, more than 3 years person 25 examples, more than 5 years person 23 examples;
Clinical manifestation mainly contains:
(l) stomatocace recurrent exerbation (annual outbreak more than 10 times), outbreak more than 1 year continuously;
(2) occur in pain, scorching hot, the xerostomia halitosis of ulcer of lip, oral mucosa, gingiva, tongue body, ulcer number 1-5, ooze out as seen, hyperemia, edema etc. show as master.
Efficacy assessment standard:
Local disease damage evaluation criteria is as the criterion with ulcer change, healing and the scorching hot degree of pain.
(1) clinical cure: after taking 1 course for the treatment of of Chinese medicine composition of the present invention, transference cure, sign disappears substantially, ulcer disease damage all healed;
(2) effective: after taking 1 course for the treatment of of Chinese medicine composition of the present invention, sign all has clear improvement, and ulcer healing reaches 2/3, or ulcer shoals and reduces;
(3) invalid: after taking 1 course for the treatment of of Chinese medicine composition of the present invention, sign is improved not obvious, and ulcer is substantially unchanged.
Result: after 50 routine refractory multiple oral ulcer persons take 1 course for the treatment of of Chinese medicine composition of the present invention, clinical cure 29 example, effective 18 examples, invalid 3 examples.Total effective rate is 94%.
Model case:
Case 1
Agriculture, man, 48 years old, be the length of teaching secondary school teachers of nearly 30 years, suffered from refractory multiple oral ulcer 7 years.Time serious, there is several ulcer point at the position such as oral mucosa, tongue, gums, and little have the grain of rice large, and large so large to Semen Viciae fabae lobe, sometimes go back oozing of blood, unbearably, difficulty of eating, even talks also influenced causalgia, therefore the sick normal work also having influence on him.He once arrived provinces and cities' large hospital and asked doctor, medicine injection, Chinese medicine Western medicine, earthwork folk prescription, oral external etc., all to no effect.He suffers untold misery for this reason.After being introduced, after taking 1 course for the treatment of of Chinese medicine composition of the embodiment of the present invention 1, surprisingly find that oral ulcer rots position in minimizing, pain is alleviating, and continue again 1 course for the treatment of of Chinese medicine composition of taking the embodiment of the present invention 2 again, oral ulcer is recovered completely.So far without recurrence after curing completely.
Case 2
Journey, female, 38 years old, suffer from 5 years refractory multiple oral ulcer, ulcer area is larger with rotting, after taking 1 course for the treatment of of Chinese medicine composition of the embodiment of the present invention 1, oral ulcer position of rotting obviously is recovered, and without sense of discomfort, has no adverse reaction, continue again 1 course for the treatment of of Chinese medicine composition of taking the embodiment of the present invention 3 again, oral ulcer is recovered completely.So far without repeatedly after curing completely.
The aforementioned description to concrete exemplary of the present invention is to illustrate and the object of illustration.These descriptions not want the present invention to be defined as disclosed precise forms, and obviously, according to above-mentioned instruction, can much change and change.The object selected exemplary embodiment and describe is to explain certain principles of the present invention and practical application thereof, thus those skilled in the art can be realized and utilize various different exemplary of the present invention and various different selection and change.Scope of the present invention is intended to limited by claims and equivalents thereof.
Claims (5)
1. be used for the treatment of a Chinese medicine composition for oral ulcer, it is characterized in that, according to ratio of weight and number, be made up of following component raw material: Radix Isatidis 9-12 part, Fructus Forsythiae 9-12 part, Herba Artemisiae Scopariae 6-9 part, Herba Taraxaci 10-15 part, Fructus Aurantii Immaturus (parched) 6-9 part, Gypsum Fibrosum 20-30 part, Radix Scutellariae 9-12 part, Caulis Lonicerae 9-15 part, classed FRUCTUS GARDENIAE 9-12 part, Rhizoma Anemarrhenae 9-12 part, Radix Rehmanniae 9-15 part, Radix Platycodonis 6-9 part, Radix Glycyrrhizae 5-10 part.
2. Chinese medicine composition according to claim 1, is characterized in that, according to ratio of weight and number, be made up of following component raw material: Radix Isatidis 12 parts, Fructus Forsythiae 10 parts, Herba Artemisiae Scopariae 6 parts, Herba Taraxaci 12 parts, Fructus Aurantii Immaturus (parched) 6 parts, Gypsum Fibrosum 30 parts, Radix Scutellariae 10 parts, Caulis Lonicerae 12 parts, classed FRUCTUS GARDENIAE 10 parts, the Rhizoma Anemarrhenae 10 parts, 15 parts, the Radix Rehmanniae, Radix Platycodonis 6 parts, Radix Glycyrrhizae 6 parts.
3. a preparation method for the Chinese medicine composition for the treatment of oral ulcer as claimed in claim 1, is characterized in that, comprise following operating procedure:
(1) according to ratio of weight and number, take required each component raw material, clean, put into decoction vessel;
(2) add water in decoction vessel in step (1), soak 30 ~ 40min, open fire, with high heat by the extremely boiling of decocting for Chinese herbal medicine in decoction vessel, then use slow fire boiling instead, decocting total time is 30 ~ 40min, Guan Huo, filters, gets filtrate and get final product.
4. preparation method according to claim 3, is characterized in that: the Chinese medicine putting into decoction vessel shakeouts in (2) by step, adding water as exceeding the water yield shakeouing rear Chinese medicine plane 3 ~ 4cm.
5. preparation method according to claim 3, is characterized in that: be filtered in step (2) and get 3 ~ 4 layers of gauze and make filter cloth and filter.
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Cited By (1)
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CN108159292A (en) * | 2017-12-21 | 2018-06-15 | 霍山县中医院 | A kind of Chinese prescription for treating canker sore |
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KR20140029646A (en) * | 2012-08-29 | 2014-03-11 | 조선대학교산학협력단 | Use of glehnia littoralis extracts for controlling prostaglandin e2 |
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