CN104800530A - Traditional Chinese medicine composition for treating oral ulcer and preparation method of traditional Chinese medicine composition - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating oral ulcers. The raw materials of the components include Radix Radix Isatidis, Forsythia, capillary, Dandelion, fried Citrus aurantium, raw gypsum, Scutellaria baicalensis, Lonicerae vine, gardenia charcoal, Zhimu, Shengdi, Platycodon grandiflorum and raw licorice; the preparation method is: weigh the required raw materials of each component, wash them, put them into a decoction device, add water, soak for 30-40 minutes, turn on the fire, and decoct the traditional Chinese medicine in the decoction device until boiling , and then switch to slow fire decoction, the total decoction time is 30-40min, turn off the heat, filter, and get the filtrate. The traditional Chinese medicine composition of the present invention aims at efficiently treating refractory and multiple oral ulcers while reducing the side effects of medication and the harm to the human body during the medication process; further preparation methods of the present invention can maximize the effectiveness of the traditional Chinese medicine composition. The medicinal effect, meanwhile, makes the preparation method more concise and easy to operate.

Description

A kind of traditional Chinese medicine composition for treating oral ulcer and preparation method thereof

technical field

The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating oral ulcers and a preparation method thereof.

Background technique

Oral ulcer is a common oral mucosal disease, also known as aphthous ulcer. The pain is very obvious during the outbreak, and it can heal without treatment. Also have recurrent exerbation, are called intractable, multiple oral ulcers, have had a great impact on the patient's work and life. The specific cause of intractable and multiple oral ulcers has not yet been determined, but its occurrence is related to many factors, such as decreased cellular immune function; digestive system diseases such as abdominal distension, diarrhea or constipation; endocrine changes; good and other mental factors; lack of trace elements zinc, iron, folic acid, vitamin Bl2, genetics and other factors. Products in the existing market include powdery sprayable medicines; granular Chinese patent medicine pills for oral administration; paste medicines include "Yi Ke Tie"; and dietotherapy. These have a certain effect on treatment, but each has its own emphasis and shortcomings. Although spray medicine can be directly applied to the affected area, the effect is faster than pills, but the medicine is easy to swallow with saliva, and the efficacy is greatly reduced; granular pills are mainly used to regulate internal demand, and the effect is slow; sticky products such as "Yi Ke Tie" need to be used Hand to operate, easy to carry bacteria and cause further infection of the wound.

The information disclosed in this Background section is only for enhancing the understanding of the general background of the present invention and should not be taken as an acknowledgment or any form of suggestion that the information constitutes the prior art that is already known to those skilled in the art.

Contents of the invention

Aiming at the technical problems in the prior art, the present invention invents a traditional Chinese medicine composition for treating ulcerative colitis, aiming at efficiently treating refractory and multiple oral ulcers while alleviating the side effects of medication so as to reduce the side effects of medication during the medication process. harm to the human body.

Another object of the present invention is to provide a preparation method of a traditional Chinese medicine composition for treating refractory and multiple oral ulcers, thereby maximizing the efficacy of the Chinese medicinal composition, and at the same time, making the preparation method more concise and easy operate.

In order to achieve the above object, the technical scheme provided by the invention is as follows:

A traditional Chinese medicine composition for treating oral ulcers, which is composed of the following component raw materials according to the ratio of parts by weight: 9-12 parts of Radix Isatidis, 9-12 parts of Forsythia, 6-9 parts of capillary, and 10-15 parts of Dandelion , 6-9 parts of fried Citrus aurantii, 20-30 parts of raw gypsum, 9-12 parts of Scutellaria baicalensis, 9-15 parts of honeysuckle, 9-12 parts of gardenia charcoal, 9-12 parts of Anemarrhena, 9-15 parts of raw land, bellflower 6-9 parts, 5-10 parts of raw licorice.

Preferably, 12 parts of Radix Isatidis, 10 parts of Forsythia, 6 parts of capillary, 12 parts of dandelion, 6 parts of fried aurantium, 30 parts of raw gypsum, 10 parts of Scutellaria baicalensis, 12 parts of honeysuckle, 10 parts of gardenia charcoal, and 10 parts of Anemarrhena 15 parts of raw land, 6 parts of bellflower, and 6 parts of raw licorice.

A preparation method of the traditional Chinese medicine composition for the treatment of oral ulcer as described above, comprising the following steps:

(1) According to the ratio of parts by weight, take the required raw materials of each component, wash them, and put them into the decoction device;

(2) Add water to the decoction device in step (1), soak for 30-40 minutes, turn on the fire, decoct the traditional Chinese medicine in the decoction device with strong fire until it boils, and then switch to slow fire for decoction, the total decoction time is 30-40 minutes , turn off the heat, filter, and get the filtrate.

Preferably, in the step (2), the traditional Chinese medicine put into the decoction device is flattened, and the amount of water added is 3-4 cm above the level of the flattened Chinese medicine.

Preferably, filtering in step (2) is to take 3 to 4 layers of gauze to make filter cloth for filtering.

The traditional Chinese medicine composition prepared by the above method is one dose, and the taking method of the traditional Chinese medicine of the present invention is as follows: one dose a day, one dose is taken twice in the morning and evening, and 7 days is a course of treatment. During the treatment period, you should eat light and digestible food, keep your mood at ease, pay attention to the balance between work and rest, and stop using other Chinese and Western medicines.

The present invention selects Radix Isatidis, Forsythia, capillary, Dandelion, fried Citrus aurantii, raw gypsum, scutellaria, honeysuckle, gardenia charcoal, Anemarrhena, raw land, platycodon grandiflorum, and raw licorice for combination, and these medicines are combined to make the effects of each medicine produce synergy.

In the traditional Chinese medicine composition of the present invention, Radix Radix isatidis clears heat and detoxifies, cools blood and relieves swelling, relieves sore throat; Protect liver function, antipyretic, anti-inflammation, lowering blood fat, lowering blood pressure; dandelion clears heat and detoxifies, eliminates carbuncle and stagnation, anti-inflammatory, cools blood, diuresis, promotes gallbladder; stir-fried aurantium aurantium dispels qi and eliminates stagnation, reduces phlegm and swelling; raw gypsum clears heat Purging fire, relieving restlessness, quenching thirst, astringing and promoting muscle growth; Scutellaria baicalensis clearing heat and dampness, cooling blood to relieve miscarriage, detoxification; Lonicera vine clearing heat and detoxifying, dredging collaterals; gardenia charcoal purging fire and relieving restlessness, clearing heat and dampness, cooling blood and detoxifying; Anemarrhena anemarrhena Clearing away heat and lowering internal heat; Habitat clears away heat and cools blood, nourishes yin, and promotes body fluid; Platycodon grandiflorum can eliminate phlegm and relieve cough, and has the effect of ventilating the lung and draining pus; Raw licorice is mainly used for sore throat, sores, gastrointestinal ulcers, and antidote to poison, food poisoning etc. All the medicines in the prescription work together to clear heat and detoxify, reduce inflammation and cool blood, remove putrefaction and promote granulation, and jointly achieve the purpose of treating intractable multiple oral ulcers.

Compared with the prior art, the present invention has the following beneficial effects:

In the present invention, the above-mentioned various Chinese medicine raw materials are rationally matched, and the ratio of the raw materials used in each component makes each raw material play a good synergistic effect, that is, each Chinese medicine exerts its efficacy, and the treatment effect is excellent, and further Yes, the preparation process of the present invention is simple, the active ingredients of each component are extracted to a greater extent during the preparation process, the curative effect of the composition is better exerted, and the dosage is reduced at the same time; and there is no adverse reaction, and the safety is very high; the medicinal properties Moderate and will not cause drug dependence.

Detailed ways

The following will be described in detail in conjunction with specific embodiments, but it should be understood that the protection scope of the present invention is not limited by specific embodiments.

Example 1

Taking g as the unit, weigh the following raw materials for each component: 12 parts of Radix Radix, 10 parts of Forsythia, 6 parts of capillary, 12 parts of Dandelion, 6 parts of fried Citrus aurantium, 30 parts of raw gypsum, 10 parts of Scutellaria baicalensis, 12 parts of Lonicera vine, 10 parts of gardenia charcoal, 10 parts of Anemarrhena, 15 parts of raw land, 6 parts of platycodon, 6 parts of raw licorice, wash the weighed herbs with water, put them in a decoction pot, add pure water, Add pure water to an amount that is 4cm higher than the level of the flattened Chinese medicine in the decoction tank; soak for 30 minutes, turn on the fire, decoct the Chinese medicine in the decoction tank with strong fire until boiling, and then immediately switch to slow fire decoction, the total time of decoction For 40 minutes, turn off the fire, filter with a filter cloth made of 4 layers of gauze, and get the filtrate.

Example 2

Taking g as the unit, weigh the following raw materials for each component: 9 parts of Radix Radix, 9 parts of Forsythia, 8 parts of Capillary, 10 parts of Dandelion, 7 parts of fried Citrus aurantium, 20 parts of raw gypsum, 9 parts of Scutellaria, 9 parts of Lonicera, 9 parts of gardenia charcoal, 9 parts of Anemarrhena, 9 parts of raw land, 8 parts of bellflower, and 5 parts of raw licorice. Wash the weighed herbs with water, put them in a decoction jar, and add pure water. Add purified water to an amount that is 3cm higher than the level of the flattened Chinese medicine in the decoction tank; soak for 35 minutes, turn on the fire, and decoct the Chinese medicine in the decoction tank until boiling with strong fire, then immediately switch to slow fire decoction, the total time of decoction For 35 minutes, turn off the fire, filter with a filter cloth made of 3 layers of gauze, and get the filtrate.

Example 3

Taking g as the unit, weigh the following ingredients: 11 parts of Radix Isatidis, 12 parts of Forsythia, 9 parts of Capillary, 15 parts of Dandelion, 9 parts of fried Citrus aurantium, 25 parts of raw gypsum, 12 parts of Scutellaria baicalensis, 15 parts of Lonicera vine, 12 parts of gardenia charcoal, 12 parts of Anemarrhena, 12 parts of raw land, 9 parts of bellflower, and 10 parts of raw licorice. Wash the weighed herbs with water, put them in a decoction pot, and add pure water. Add pure water to an amount that is 3cm higher than the level of the flattened Chinese medicine in the decoction tank; soak for 40 minutes, turn on the fire, decoct the Chinese medicine in the decoction tank with strong fire until boiling, and then immediately switch to slow fire decoction, the total time of decoction For 30 minutes, turn off the fire, filter with a filter cloth made of 4 layers of gauze, and get the filtrate.

Efficacy survey

In order to test the therapeutic effect of the present invention, 50 cases of intractable and multiple oral ulcers were selected to be treated with the Chinese medicine composition prepared by the above-mentioned embodiments of the present invention. Among them, there were 28 males and 22 females, aged 26-56 years, with an average age of 36 years. 2 cases were within 3 years, 25 cases were over 3 years, and 23 cases were over 5 years;

Clinical manifestations mainly include:

(l) Recurrent oral mucosal ulcers (more than 10 attacks per year) for more than 1 year in a row;

(2) Pain, burning, dry mouth and halitosis of ulcers that occur on the lips, oral mucosa, gums, and tongue. The number of ulcers is 1-5, and the main manifestations are exudation, congestion, and edema.

Efficacy evaluation criteria:

Evaluation criteria for local lesions were based on ulcer changes, degree of healing, and degree of pain and burning.

(1) clinical cure: after taking 1 course of treatment of Chinese medicine composition of the present invention, symptom disappears, sign disappears substantially, and ulcer lesion is all healed;

(2) effective: after taking the traditional Chinese medicine composition of the present invention for 1 course of treatment, the physical signs are obviously improved, and the ulcer heals up to 2/3, or the ulcer becomes shallow and shrinks;

(3) Ineffective: After taking the traditional Chinese medicine composition of the present invention for 1 course of treatment, the physical signs were not significantly improved, and the ulcers did not change substantially.

Results: After 50 cases of refractory multiple oral ulcers were taken for a course of treatment with the traditional Chinese medicine composition of the present invention, 29 cases were clinically cured, 18 cases were effective, and 3 cases were ineffective. The total effective rate is 94%.

Typical cases:

Case 1

Nong, male, 48 years old, is a middle school teacher with nearly 30 years of teaching experience, suffering from refractory multiple oral ulcers for 7 years. In severe cases, there are several ulcers on the oral mucosa, tongue, gums, etc., ranging from the size of rice grains to the size of broad bean flaps. Sometimes, blood oozes, burning pain is unbearable, it is difficult to swallow, and even speech is affected. affect his normal work. He went to provincial and municipal large hospitals to seek medical treatment, took medicine and injections, traditional Chinese medicine and Western medicine, folk remedies, oral and external application, etc., but nothing worked. He was miserable about it. After being introduced by someone, after taking the traditional Chinese medicine composition of the embodiment 1 of the present invention for a course of treatment, it was pleasantly found that the rotten parts of the oral ulcers were decreasing, and the pain was alleviated, and then continued to take one Chinese medicinal composition of the embodiment 2 of the present invention The course of treatment, oral ulcer fully recovered. So far no recurrence after complete cure.

Case 2

Cheng, female, 38 years old, suffered from 5 years of intractable multiple oral ulcers, and the ulcer area was relatively large accompanied by rot. After taking the traditional Chinese medicine composition of the embodiment 1 of the present invention for 1 course of treatment, the rotten parts of the oral ulcer recovered obviously, without discomfort Feeling, without adverse reaction, continue to take 1 course of treatment of the Chinese medicine composition of the embodiment of the present invention 3 again again, oral ulcer recovers fully. So far no recurrence after complete cure.

The foregoing descriptions of specific exemplary embodiments of the present invention have been presented for purposes of illustration and description. These descriptions are not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain the specific principles of the invention and its practical application, thereby enabling others skilled in the art to make and use various exemplary embodiments of the invention, as well as various Choose and change. It is intended that the scope of the invention be defined by the claims and their equivalents.

Claims (5)

1. be used for the treatment of a Chinese medicine composition for oral ulcer, it is characterized in that, according to ratio of weight and number, be made up of following component raw material: Radix Isatidis 9-12 part, Fructus Forsythiae 9-12 part, Herba Artemisiae Scopariae 6-9 part, Herba Taraxaci 10-15 part, Fructus Aurantii Immaturus (parched) 6-9 part, Gypsum Fibrosum 20-30 part, Radix Scutellariae 9-12 part, Caulis Lonicerae 9-15 part, classed FRUCTUS GARDENIAE 9-12 part, Rhizoma Anemarrhenae 9-12 part, Radix Rehmanniae 9-15 part, Radix Platycodonis 6-9 part, Radix Glycyrrhizae 5-10 part.

2. Chinese medicine composition according to claim 1, is characterized in that, according to ratio of weight and number, be made up of following component raw material: Radix Isatidis 12 parts, Fructus Forsythiae 10 parts, Herba Artemisiae Scopariae 6 parts, Herba Taraxaci 12 parts, Fructus Aurantii Immaturus (parched) 6 parts, Gypsum Fibrosum 30 parts, Radix Scutellariae 10 parts, Caulis Lonicerae 12 parts, classed FRUCTUS GARDENIAE 10 parts, the Rhizoma Anemarrhenae 10 parts, 15 parts, the Radix Rehmanniae, Radix Platycodonis 6 parts, Radix Glycyrrhizae 6 parts.

3. a preparation method for the Chinese medicine composition for the treatment of oral ulcer as claimed in claim 1, is characterized in that, comprise following operating procedure:

(1) according to ratio of weight and number, take required each component raw material, clean, put into decoction vessel;

(2) add water in decoction vessel in step (1), soak 30 ~ 40min, open fire, with high heat by the extremely boiling of decocting for Chinese herbal medicine in decoction vessel, then use slow fire boiling instead, decocting total time is 30 ~ 40min, Guan Huo, filters, gets filtrate and get final product.

4. preparation method according to claim 3, is characterized in that: the Chinese medicine putting into decoction vessel shakeouts in (2) by step, adding water as exceeding the water yield shakeouing rear Chinese medicine plane 3 ~ 4cm.

5. preparation method according to claim 3, is characterized in that: be filtered in step (2) and get 3 ~ 4 layers of gauze and make filter cloth and filter.