CN104800422A - Tea tree essential oil for treating groin tinea and preparation method thereof - Google Patents

Tea tree essential oil for treating groin tinea and preparation method thereof Download PDF

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CN104800422A
CN104800422A CN201510159427.0A CN201510159427A CN104800422A CN 104800422 A CN104800422 A CN 104800422A CN 201510159427 A CN201510159427 A CN 201510159427A CN 104800422 A CN104800422 A CN 104800422A
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oil
tea tree
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fructus
tree ethereal
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范永启
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Abstract

The invention discloses tea tree essential oil for treating groin tinea and a preparation method thereof. The tea tree essential oil is prepared from the following raw materials in parts by weight: 5-10 parts of radix ampelopsis, 4-9 parts of Chinese tallow tree seeds, 8-12 parts of all-grass of winkled marshweed, 6-9 parts of common carpesium fruit, 5-9 parts of croton seeds, 9-15 parts of wild chrysanthemum, 9-15 parts of forsythia suspense, 5-8 parts of carrot seed oil, 1.3-1.7 parts of Germany chamomile, 1.0-1.5 parts of niaouli essential oil and 1.2-1.6 parts of tea tree essential oil. The tea tree essential oil provided by the invention has the excellent effects as follows: natural extraction essential oil and traditional Chinese medicines are used as raw materials, so that the tea tree essential oil takes effects quickly, is exact in curative effect, does not contain any hormone or chemical components, does not cause secondary injury to human bodies and is safe and effective; essential oil which has a repair effect on skin epithelial cells is added into the components of the tea tree essential oil, so that funguses can be killed basically, damaged cells are eliminated and the purpose of rapid skin regeneration is realized.

Description

A kind of tea tree ethereal oil and preparation method for the treatment of epidermophytosis inguinale
Technical field
The present invention relates to a kind of quintessence oil, particularly relate to a kind of tea tree ethereal oil and preparation method for the treatment of epidermophytosis inguinale.
Background technology
Epidermophytosis inguinale, also known as tinea cruris, is a kind ofly invade groin and surrounding skin thereof by dermatophytosis and with the infectious disease of remarkable pruritus, be the specific type of tinea corporis at genitocrural.Primary disease sickness rate is high, easy recurrence and infecting again, especially people are not enough to primary disease understanding, in addition lack of standardization, irrational treatment causes tinea cruris recurrent exerbation, repeatedly treat, impact in various degree is all caused on quality of life of patient and health status, all significant wastage is caused to individual economy and social medical resource.Therefore, try to explore the method for effectively treating tinea cruris, have important medical value and social meaning.
Primary disease easily occurred in the season of warmed moist, the outstanding susceptible disease of male hyperhidrosis person.Special work post is as driver, long-term seat person also susceptible disease.Often betide the thigh skin of scrotum offside, side or bilateral, how in the form of a ring or semicircular patch.Common tinea cruris pathomycete comprises trichophyton, alpha fungus, Sabouraudites lanosus, Candida albicans etc.Latter two bacterium animal is bacillicarrier, therefore often suffers from the cat, dog etc. of tinea bacterium by contact and catch an illness.Onset be syringe needle to Semen phaseoli radiati size pimple, vesicle or papulovesicle, outwards develop from center, center inflammation alleviates, and edge is examined by the pimple be dispersed in, vesicle, mound bleb, crust and squama connect into ring-type and swell, and the infringement of multilayer concentric circle sample can appear in central part again.Pruritus is obvious, local eczema sample can be caused to change, easy secondary bacterial infection after scratching.General summer and autumn, onset or exacerbation of symptoms, alleviated or static winter, left pigmentation more afterwards.The infringement inflammation that the trichophyton of relatives' property causes is less obvious, and often present large lamellar, number is less, has pigmentation more more, and recurrence erythra often presents kermesinus or sepia, blur margin Chu.Traditional medicine thinks that the damp and hot heresy of this type of disease polydipsia is followed passages through which vital energy circulates and steamed skin, meridians outward, cause the local blood stasis of blood stagnant caused by.
Application publication number CN 103386058 A(application number 201310276400.0) Chinese patent literature disclose a kind of medicine and preparation method for the treatment of tinea corporis and cruris, it is made up of the raw material of following weight proportioning: Radix Sophorae Flavescentis 10-20, Fructus Kochiae 20-60, Herba Impatientis 30-50 part, Cortex Hibisci 30-50 part, Rhizoma Atractylodis 10-50 part, Cortex Phellodendri 10-50 part, Herba Chenopodii 10-50 part, Herba Artemisiae Annuae 10-40 part, Alumen 10-60 part, Borax 10-60 part, Fructus Cnidii 10-50 part, Cortex Dictamni 10-50 part, Fructus Zanthoxyli 10-40 part, Radix Aristolochiae 60-80, Radix Stemonae 20-50, Folium Artemisiae Argyi 10-20, Fructus Zanthoxyli 5-10, Rhizoma Coptidis 20-40, dried Alumen 40-80, Borneolum Syntheticum 12-14, vinegar 10-60.Application publication number CN 103550353 A(application number 201310500456.X) Chinese invention patent document disclose a kind of Chinese medicine external-use liniment for the treatment of femoribus internus tinea cruris, form by accounting for the 0.3%-0.9% Herba speranskiae tuberculatae of total amount, 0.25%-0.5% Radix Sophorae Flavescentis, 0.2%-0.5% Cortex Phellodendri, 0.15%-0.5% Rhizoma Atractylodis and 30%-60% glycerol.Application publication number CN 104189193 A(application number 201410468466.4) Chinese invention patent document disclose a kind of tinea corporis and cruris Traditional Chinese medicine medicated bath and preparation method, be prepared from by the primary raw material of following weight proportioning: Lacca 12-16 part; Semen Hydnocarpi 9-18 part; Radix Carpesii 20-35 part; Periostracum Cicadae 10-20 part; Radix Et Rhizoma Rhei 8-16 part; Cortex Moutan 12-24 part; Herba Galii Teneri 10-16 part; Bombyx Batryticatus 5-12 part; (life) Semen Armeniacae Amarum 6-15 part; Dried Alumen 5-12 part; Calamina 6-15 part; Nidus Vespae 6-18 part; Semen Caesalpiniae 3-8 part; Zaocys 10-15 part; Hydrargyrum chloratum Compositum 8-12 part; Radix Sophorae Flavescentis 9-18 part; Cortex Phellodendri 6-15 part; Fructus Carpesii 15-25 part
The medicine for the treatment of epidermophytosis inguinale involved in prior art, although killing pathogenic bacteria that can be very fast, mitigate the disease, easily recurs after drug withdrawal, and has stronger zest to skin.Therefore research and development are a kind of safe and effective, and gentle inirritative medicine is very important.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of tea tree ethereal oil preparing treatment epidermophytosis inguinale simple, easy to use.This tea tree ethereal oil Be very effective, the property of medicine are gentle, evident in efficacy.
Technical scheme of the present invention is:
Treat a tea tree ethereal oil for epidermophytosis inguinale, be prepared from by following bulk drugs, be weight portion: Radix Ampelopsis 5-10; Chinese tallow seed 4-9; Herba Limnophilae rugosae 8-12; Fructus Carpesii 6-9; Fructus Crotonis 5-9; Flos Chrysanthemi Indici 9-15; Fructus Forsythiae 9-15; Fructus Dauci Sativae oil 5-8; Matricaria recutita quintessence oil 1.3-1.7; LVHUA 100,000 layers of quintessence oil 1.0-1.5; Tea tree ethereal oil 1.2-1.6.
In preferred scheme, Radix Ampelopsis 6-9; Chinese tallow seed 5-8; Herba Limnophilae rugosae 9-11; Fructus Carpesii 7-8; Fructus Crotonis 6-8; Flos Chrysanthemi Indici 11-13; Fructus Forsythiae 11-13; Fructus Dauci Sativae oil 6-7; Matricaria recutita quintessence oil 1.4-1.6; LVHUA 100,000 layers of quintessence oil 1.1-1.4; Tea tree ethereal oil 1.3-1.5.
Be more preferably, Radix Ampelopsis 7.5; Chinese tallow seed 6.5; Herba Limnophilae rugosae 10; Fructus Carpesii 7.5; Fructus Crotonis 7; Flos Chrysanthemi Indici 12; Fructus Forsythiae 12; Fructus Dauci Sativae oil 6.5; Matricaria recutita quintessence oil 1.5; LVHUA 100,000 layers of quintessence oil 1.25; Tea tree ethereal oil 1.4.
Treat a tea tree ethereal oil for epidermophytosis inguinale, preparation method is as follows:
(1) Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae are together placed in thermostatic drying chamber dry, take out, be ground into fine powder, obtain mixed powder for subsequent use;
(2) step (1) gained mixed powder is placed in apparatus,Soxhlet's, add the ethanol that mass concentration is 80%, heating and refluxing extraction twice, first time reflux, extract, 1.2-1.8 hour, second time reflux, extract, 30-50 minute, merges extracted twice liquid, filter, distilling under reduced pressure, reclaims ethanol, obtains Chinese medicine oil;
(3) step (2) gained Chinese medicine oil is cooled to room temperature, adds Fructus Dauci Sativae oil, magnetic agitation 4-10 minute, and then add Matricaria recutita quintessence oil, LVHUA 100,000 layers of quintessence oil and tea tree ethereal oil while stirring, mix homogeneously, obtains compound essential Oil;
(4) by the sterilizing of above-mentioned gained quintessence oil, encapsulation, to obtain final product.
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale, preferred scheme is, temperature dry in step (1) is 43-57 DEG C (preferred dry temperature is 48-52 DEG C, and the temperature of the drying be more preferably is 50 DEG C).
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale, preferred scheme is, the time dry in step (1) is 35-50 minute (the preferred dry time is 40-45 minute, and the time of the drying be more preferably is 43 minutes).
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale, preferred scheme is, the ethanol (preferably adding the ethanol of 5-7 times of mixed powder amount, the ethanol adding 6 times of mixed powder amounts be more preferably) of 4-8 times of mixed powder amount is added in step (2).
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale, preferred scheme is, reflux, extract, 1.4-1.6 hour first time (preferred reflux, extract, for the first time 1.5 hours) in step (2).
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale, preferred scheme is, second time reflux, extract, 35-45 minute (preferably second time reflux, extract, 40 minutes) in step (2).
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale, preferred scheme is, in step (3) magnetic agitation 6-8 minute (preferred magnetic agitation 7 minutes).
Tea tree ethereal oil scientific formula provided by the invention, products obtained therefrom is easy to use, be easy to carry.In addition, excellent results of the present invention also shows:
1,the present invention adopts natural extraction quintessence oil and Chinese medicine material to be raw material, and rapidly, determined curative effect, not containing any hormone and chemical composition, can not cause secondary injury to human body, safe and effective in effect;
2,quintessence oil skin epidermal cells to repair is with the addition of in instant component, can fundamentally killing fungus, eliminate damaged cell, what realize skin reproduces object fast.
3,can not produce other dangerous chemicals after quintessence oil mixing contained by the present invention, fragrance is clearly insulted ice-cold, and medical material used is simple and easy to get, is convenient to clinical application.
Effect of the present invention's primary raw material used is as follows:
Radix Ampelopsis: base is former: be the root of vitaceae Radix Ampelopsis.Chemical analysis: mucous matter, starch etc.Nature and flavor: bitter sweet pungent, cool.Gui Jing: enter the heart, liver, spleen channel.Function cures mainly; Heat clearing away, removing toxic substances, eliminating stagnation, granulation promoting, pain relieving, controls carbuncle, furuncle, scrofula, scalds, pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula.
Chinese tallow seed: base is former: be the seed of euphorbia plant Cortex Sapii Radicis.Nature and flavor: sweet are cool, poisonous.Function cures mainly: parasite killing, diuretic, relieving constipation.Control scabies, eczema, chapped skin, edema.Constipation.
Herba Limnophilae rugosae: base is former: be the herb of charophyta kind of plant Herba Limnophilae rugosae.Nature and flavor: pungent are flat.Function cures mainly: wind and heat dispersing, dampness removing cough-relieving.
Fructus Carpesii: base is former: this product is the dry mature fruit of feverfew Radix Carpesii.Character: this product is cylindric, tiny.Surface yellowish-brown or crineous, the vertical rib of tool majority.Top is shunk in thin beak, and tip is extended to canescence annulus; Base portion is slightly sharp, has raw vestige.Nature and flavor: bitter, pungent are flat; Slightly poisonous.Gui Jing: return spleen, stomach warp.Effect: killing insect and eliminating accumulation.Cure mainly: for ascarid, pinworm, taeniasis, abdominal pain due to worm stagnation, infantile malnutrition.
Fructus Crotonis: base is former: be the seed of euphorbia plant Fructus Crotonis.Chemical analysis: containing Oleum Tiglii, wherein has the glyceride of oleic acid, linoleic acid, crotonic acid, tiglic acid etc.; Still containing crotonoside.Nature and flavor: pungent, heat, poisonous.Gui Jing: enter stomach, large intestine channel.Function cures mainly: rush down cold long-pending, orifice opening, by expectorant, and row water, parasite killing.Control cold long-pending sluggish, distension and fullness of the chest and abdomen shoot, abdominal mass due to blood stasis, accumulation of phlegm in the hypochondrium, dysentery, edema, acute throat trouble is controlled in external, sore throat, malignant boil scabies.
Flos Chrysanthemi Indici: base is former: be root or the herb of Compositae Dendranthema Flos Chrysanthemi Indici or lavandulaleaf dendranthema herb.The property of medicine: bitter, acrid, cold.Return liver, heart channel.Function cures mainly: heat-clearing and toxic substances removing, improving eyesight.Cure mainly flu, dysentery, carbuncle, furuncle, conjunctival congestion and swelling pain, dizzy, scrofula, eczema.
Fructus Forsythiae: base is former: this product is the dry fruit of Oleaceae plants Fructus Forsythiae.Character: this product is in long avette to avette, slightly flat.There is the fleck of irregular vertical wrinkle and most projection on surface, and respectively there is 1 obvious longitudinal furrow on two sides.The sharp point in top.Nature and flavor: bitter, are slightly cold.Gui Jing: return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly: for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Fructus Dauci Sativae oil: distill from Daucus carota L. and obtain.Effect: the flatulence ` that dispels promote cell regeneration, purify the blood, diuresis, stimulate the menstrual flow, nourishing the liver, excitation, reinforcement, anthelmintic.Health curative effect: be splendid health clean oil, because it has effect of removing toxic substances to liver.Also useful jaundice and other liver problems, auxiliary elimination renal calculus, the effect improving hepatitis is very famous; Also can bowel relieving, control flatulence, restrain diarrhoea, the pain of gastric ulcer can be relaxed.The moisture of delay can be disengaged, alleviate cystitis.Skin curative effect: carrot seed seed oil can strengthen erythrocyte, so can improve the colour of skin, more consolidation is flexible to make skin.Skin after using has youthened vigor, and also can desalinate senile plaque, be the liberator of senilism skin.
Matricaria recutita quintessence oil: extracting mode: distillation mode extracts precious Flos Matricariae chamomillae oil.Effect: anemia, headache, otalgia, toothache, gastric ulcer, abdominal pain diarrhea, flatulence, muscular soreness, dry skin, sensitive skin, pimples, herpes, eczema, tinea, microvascular, menstruation has some setbacks, menstrual pain, insomnia, alleviates melancholy uneasy.
LVHUA 100,000 layers of quintessence oil: abnormal smells from the patient: Melaleuca oil is with the Camphora fragrance of Fructus Piperis acid.Composition: Cedrus deoclar (Roxb.) G. Don, cypress, Fructus anethi, eucalyptus globolus, Fructus Foeniculi, jasmine, gin, lavandula angustifolia, Fructus Citri sinensis, lavender, pine, Herba Rosmarini Officinalis.Chemical composition: Rhizoma Melaleuca Viridiflora essence main body of oil eucalyptole, dipentene or terpinene, limonene, phellandrene, sobrerone or pinene, linalool and menthone.Rhizoma Melaleuca Viridiflora quintessence oil extracts from Rhizoma Melaleuca Viridiflora plant, belongs to Myrtaceae.It has anticorrosion and excitation effect significantly, is widely used in treatment infection and waits disease.Effect: Rhizoma Melaleuca Viridiflora quintessence oil contributes to improving attention, makes brains keep clear-headed, can also excite inspiration.Because it has good antisepsis and sterilization effect, effectively can treat the symptom of infection, as flu, fever, influenza, thoracic cavity inflammation, bronchitis, pulmonary tuberculosis, pneumonia, cough, asthma, sinusitis, pharyngolaryngitis, mucositis and laryngitis.In addition, also contribute to treatment enteritis, dysentery, Enterozoa, cystitis and urinary infection, also can alleviate neural and rheumatismal pain.As a kind of anti-infective, Rhizoma Melaleuca Viridiflora quintessence oil can be used for cleaning a wound, and removes ulcer, acne, stain, furuncle, burn, incised wound, mosquito bite, and as the decongestant that skin uses.
Tea tree ethereal oil: tea tree ethereal oil originates in Australia is the extract of Camellia sinensis.Abnormal smells from the patient: approximate eucalyptus globolus, fresh, slightly pungent wooden class aromatic, has dense flavour of a drug, fresh, pure and fresh, slightly pungent.Volatility: fast.Composition: topmost chemical composition is ethylene, dipentene, limonene, cineol, Oleum sesami brain, anisoxide.Function: 1, psychological effect: make brains pure and fresh, rejuvenate, be particularly useful for frightened situation.2, health curative effect: the most important purposes of Camellia sinensis helps the communicable disease of immune system fight, and instigate leukocyte and form guard wire, to meet head on the organism of invasion, and can shorten the time of falling ill, be potent antibiotic essential oil.3, skin curative effect: clean-up effect is excellent, improves the suppuration phenomenon of wound infection, and furuncle.Remove small pox and unclean position caused by chickenpox and herpes zoster.Can be applicable to burn, skin ulcer, sunburn, tinea, wart, tinea circinata, herpes and tinea pedis.Also scalp overdrying and the dandruff can be treated.4, sterilize master-hand: 5 folk prescription tea tree ethereal oil champignons, with the antibacterial in purifying air, viral expelling mosquito.5, other effects: tea tree ethereal oil effect has bactericidal antiphlogistic, convergence pore, treatment Common Cold, cough, rhinitis, asthma, improve dysmenorrhea, menoxenia and genital infection.Be applicable to oiliness and acne-prone skin, treatment suppurative wound and burn, tan severely, tinea pedis and dandruff.Clear the head, rejuvenate, anti-dejected.6, beauty functions: the research through expert finds, tea tree ethereal oil utilizes the effect of its anti-inflammation, effectively can resist the small pox that propionibacterium acnes causes.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a tea tree ethereal oil for epidermophytosis inguinale, be prepared from by following bulk drugs, be weight portion (50g/ part): Radix Ampelopsis 5 parts; Chinese tallow seed 4 parts; Herba Limnophilae rugosae 8 parts; Fructus Carpesii 6 parts; Fructus Crotonis 5 parts; Flos Chrysanthemi Indici 9 parts; Fructus Forsythiae 9 parts; Fructus Dauci Sativae oil 5 parts; Matricaria recutita quintessence oil 1.3 parts; LVHUA 100,000 layers of quintessence oil 1.0 parts; Tea tree ethereal oil 1.2 parts.
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale is:
(1) Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae are together placed in thermostatic drying chamber in 43 DEG C of dryings 35 minutes, take out, be ground into fine powder, obtain mixed powder for subsequent use;
(2) step (1) gained mixed powder is placed in apparatus,Soxhlet's, the mass concentration adding 4 times of mixed powder amounts is the ethanol of 80%, heating and refluxing extraction twice, reflux, extract, 1.2 hours for the first time, second time reflux, extract, 30 minutes, merges extracted twice liquid, filter, distilling under reduced pressure, reclaims ethanol, obtains Chinese medicine oil;
(3) step (2) gained Chinese medicine oil is cooled to room temperature, add Fructus Dauci Sativae oil (the global natural perfume material company limited in Jiangxi, content 99%, 100mL/ bottle), magnetic agitation 4 minutes, then Matricaria recutita quintessence oil (Shanghai Po Li trade Co., Ltd is added while stirring, 10mL/ bottle), LVHUA 100,000 layers of quintessence oil (Shanghai Po Li trade Co., Ltd, 30mL/ bottle) and tea tree ethereal oil (the organic unlimited trade Co., Ltd in Shenzhen, specification: 50mL/ bottle), mix homogeneously, obtains compound essential Oil;
(4) by the sterilizing of above-mentioned gained quintessence oil, encapsulation, to obtain final product.
The using method of tea tree ethereal oil of the present invention is: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.
embodiment 2treat a tea tree ethereal oil for epidermophytosis inguinale, be prepared from by following bulk drugs, be weight portion (30g/ part): Radix Ampelopsis 10 parts; Chinese tallow seed 9 parts; Herba Limnophilae rugosae 12 parts; Fructus Carpesii 9 parts; Fructus Crotonis 9 parts; Flos Chrysanthemi Indici 15 parts; Fructus Forsythiae 15 parts; Fructus Dauci Sativae oil 8 parts; Matricaria recutita quintessence oil 1.7 parts; LVHUA 100,000 layers of quintessence oil 1.5 parts; Tea tree ethereal oil 1.6 parts.
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale is:
(1) Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae are together placed in thermostatic drying chamber in 57 DEG C of dryings 50 minutes, take out, be ground into fine powder, obtain mixed powder for subsequent use;
(2) step (1) gained mixed powder is placed in apparatus,Soxhlet's, the mass concentration adding 8 times of mixed powder amounts is the ethanol of 80%, heating and refluxing extraction twice, reflux, extract, 1.8 hours for the first time, second time reflux, extract, 50 minutes, merges extracted twice liquid, filter, distilling under reduced pressure, reclaims ethanol, obtains Chinese medicine oil;
(3) step (2) gained Chinese medicine oil is cooled to room temperature, add Fructus Dauci Sativae oil (the global natural perfume material company limited in Jiangxi, content 99%, 100mL/ bottle), magnetic agitation 10 minutes, then Matricaria recutita quintessence oil (Shanghai Po Li trade Co., Ltd is added while stirring, 10mL/ bottle), LVHUA 100,000 layers of quintessence oil (Shanghai Po Li trade Co., Ltd, 30mL/ bottle) and tea tree ethereal oil (the organic unlimited trade Co., Ltd in Shenzhen, specification: 50mL/ bottle), mix homogeneously, obtains compound essential Oil;
(4) by the sterilizing of above-mentioned gained quintessence oil, encapsulation, to obtain final product.
The using method of tea tree ethereal oil of the present invention is: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.
Model case: Cui XX, man, 49 years old, bus driver.Mr. Cui is engaged in driver's industry and has a surplus for 6 years, no matter stand fast on post in freezing winter and in sultry summer always, fulfils one's duty, is cited as model driver for many years.Since in July, 2012, Mr.'s Cui femoribus internus groin place usually feels scratchy, time particularly sky heat is perspired.Have erythema of the grain of rice size during beginning, edge then has many red pimples, blister, pus to steep and squama.Mr. Cui is diagnosed as tinea cruris in local hospital inspection, and after medication treatment, DeGrain, comes my institute after being introduced and check treatment.Check: the focus of symmetry boundary obviously in half moon occurs inside patient thigh, the scorching disease of focus central authorities goes down or disappears, and edge then has many red pimples, blister, pus to steep and squama.Be diagnosed as epidermophytosis inguinale.
Use a kind of tea tree ethereal oil for the treatment of epidermophytosis inguinale of the present embodiment gained, using method: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.After the course for the treatment of of patient medication, pain and scratchy obvious alleviation, erythema fades away; After continuing a course for the treatment of of medication, patient's malaise symptoms major part disappears, without pain, scratchy symptom; Exhort and continue a course for the treatment of of medication, patient fully recovers.Pay a return visit after three months, without recurrence.
embodiment 3treat a tea tree ethereal oil for epidermophytosis inguinale, be prepared from by following bulk drugs, be weight portion (45g/ part): Radix Ampelopsis 6 parts; Chinese tallow seed 5 parts; Herba Limnophilae rugosae 9 parts; Fructus Carpesii 7 parts; Fructus Crotonis 6 parts; Flos Chrysanthemi Indici 11 parts; Fructus Forsythiae 11 parts; Fructus Dauci Sativae oil 6 parts; Matricaria recutita quintessence oil 1.4 parts; LVHUA 100,000 layers of quintessence oil 1.1 parts; Tea tree ethereal oil 1.3 parts.
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale is:
(1) Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae are together placed in thermostatic drying chamber in 48 DEG C of dryings 40 minutes, take out, be ground into fine powder, obtain mixed powder for subsequent use;
(2) step (1) gained mixed powder is placed in apparatus,Soxhlet's, the mass concentration adding 5 times of mixed powder amounts is the ethanol of 80%, heating and refluxing extraction twice, reflux, extract, 1.4 hours for the first time, second time reflux, extract, 35 minutes, merges extracted twice liquid, filter, distilling under reduced pressure, reclaims ethanol, obtains Chinese medicine oil;
(3) step (2) gained Chinese medicine oil is cooled to room temperature, add Fructus Dauci Sativae oil (the global natural perfume material company limited in Jiangxi, content 99%, 100mL/ bottle), magnetic agitation 6 minutes, then Matricaria recutita quintessence oil (Shanghai Po Li trade Co., Ltd is added while stirring, 10mL/ bottle), LVHUA 100,000 layers of quintessence oil (Shanghai Po Li trade Co., Ltd, 30mL/ bottle) and tea tree ethereal oil (the organic unlimited trade Co., Ltd in Shenzhen, specification: 50mL/ bottle), mix homogeneously, obtains compound essential Oil;
(4) by the sterilizing of above-mentioned gained quintessence oil, encapsulation, to obtain final product.
The using method of tea tree ethereal oil of the present invention is: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.
embodiment 4treat a tea tree ethereal oil for epidermophytosis inguinale, be prepared from by following bulk drugs, be weight portion (35g/ part): Radix Ampelopsis 9 parts; Chinese tallow seed 8 parts; Herba Limnophilae rugosae 11 parts; Fructus Carpesii 8 parts; Fructus Crotonis 8 parts; Flos Chrysanthemi Indici 13 parts; Fructus Forsythiae 13 parts; Fructus Dauci Sativae oil 7 parts; Matricaria recutita quintessence oil 1.6 parts; LVHUA 100,000 layers of quintessence oil 1.4 parts; Tea tree ethereal oil 1.5 parts.
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale is:
(1) Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae are together placed in thermostatic drying chamber in 52 DEG C of dryings 45 minutes, take out, be ground into fine powder, obtain mixed powder for subsequent use;
(2) step (1) gained mixed powder is placed in apparatus,Soxhlet's, the mass concentration adding 7 times of mixed powder amounts is the ethanol of 80%, heating and refluxing extraction twice, reflux, extract, 1.6 hours for the first time, second time reflux, extract, 45 minutes, merges extracted twice liquid, filter, distilling under reduced pressure, reclaims ethanol, obtains Chinese medicine oil;
(3) step (2) gained Chinese medicine oil is cooled to room temperature, add Fructus Dauci Sativae oil (the global natural perfume material company limited in Jiangxi, content 99%, 100mL/ bottle), magnetic agitation 8 minutes, then Matricaria recutita quintessence oil (Shanghai Po Li trade Co., Ltd is added while stirring, 10mL/ bottle), LVHUA 100,000 layers of quintessence oil (Shanghai Po Li trade Co., Ltd, 30mL/ bottle) and tea tree ethereal oil (the organic unlimited trade Co., Ltd in Shenzhen, specification: 50mL/ bottle), mix homogeneously, obtains compound essential Oil;
(4) by the sterilizing of above-mentioned gained quintessence oil, encapsulation, to obtain final product.
The using method of tea tree ethereal oil of the present invention is: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.
Model case: Liu XX, man, 50 years old, teacher.August 23 in 2012, people was to our hospital.Patient's readme: without obvious inducement femoribus internus before two weeks, the tinea of the oval circle in groin side, just started symptom comparatively light, slightly keenly feel when walking, tinea slowly became large afterwards, cylindrical is red, not only pain but also itch, walking along the street difficulty, once with PIYANPING and PIKANGWANG treatment, the state of an illness is slightly alleviated, and recurs after drug withdrawal.Introduced here treatment through friend afterwards.Describe and lab testing according to patient, be diagnosed as fungus-caused epidermophytosis inguinale.
Use a kind of tea tree ethereal oil for the treatment of epidermophytosis inguinale of the present embodiment gained, using method: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.After the course for the treatment of of patient medication, pain and pruritus are obviously alleviated, and tinea fades away; After continuing a course for the treatment of of medication, patient's malaise symptoms all disappears, and plays tinea place skin and slowly recovers, and exhort that continuing medication is consolidated a course for the treatment of, patient fully recovers.Pay a return visit after three months, without recurrence.
embodiment 5treat a tea tree ethereal oil for epidermophytosis inguinale, be prepared from by following bulk drugs, be weight portion (40g/ part): Radix Ampelopsis 7.5 parts; Chinese tallow seed 6.5 parts; Herba Limnophilae rugosae 10 parts; Fructus Carpesii 7.5 parts; Fructus Crotonis 7 parts; Flos Chrysanthemi Indici 12 parts; Fructus Forsythiae 12 parts; Fructus Dauci Sativae oil 6.5 parts; Matricaria recutita quintessence oil 1.5 parts; LVHUA 100,000 layers of quintessence oil 1.25 parts; Tea tree ethereal oil 1.4 parts.
Above-mentioned a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale is:
(1) Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae are together placed in thermostatic drying chamber in 50 DEG C of dryings 43 minutes, take out, be ground into fine powder, obtain mixed powder for subsequent use;
(2) step (1) gained mixed powder is placed in apparatus,Soxhlet's, the mass concentration adding 6 times of mixed powder amounts is the ethanol of 80%, heating and refluxing extraction twice, reflux, extract, 1.5 hours for the first time, second time reflux, extract, 40 minutes, merges extracted twice liquid, filter, distilling under reduced pressure, reclaims ethanol, obtains Chinese medicine oil;
(3) step (2) gained Chinese medicine oil is cooled to room temperature, add Fructus Dauci Sativae oil (the global natural perfume material company limited in Jiangxi, content 99%, 100mL/ bottle), magnetic agitation 7 minutes, then Matricaria recutita quintessence oil (Shanghai Po Li trade Co., Ltd is added while stirring, 10mL/ bottle), LVHUA 100,000 layers of quintessence oil (Shanghai Po Li trade Co., Ltd, 30mL/ bottle) and tea tree ethereal oil (the organic unlimited trade Co., Ltd in Shenzhen, specification: 50mL/ bottle), mix homogeneously, obtains compound essential Oil;
(4) by the sterilizing of above-mentioned gained quintessence oil, encapsulation, to obtain final product.
The using method of tea tree ethereal oil of the present invention is: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.
test example 1a kind of clinical practice for the treatment of the tea tree ethereal oil (embodiment 5) of epidermophytosis inguinale of gained of the present invention: in June ,-2012 in April, 2011, the experimenter of the routine voluntary participation test of screening 300, wherein male 183 example, women 117 example; Age is in 32-55 year.All patients make a definite diagnosis according to clinical manifestation, skin lesion form and Mycology examination suffers from epidermophytosis inguinale.All experimenters are divided into experimental group and matched group at random.Two groups of personnel through statistical procedures no significant difference (P > 0.05), have comparability in the state of an illness, the course of disease etc.Wherein experimental group uses a kind of tea tree ethereal oil for the treatment of epidermophytosis inguinale of gained of the present invention, using method: get appropriate this product and be applied to affected part, every day three times, 4 days courses for the treatment of.Matched group uses other medicines (as clean in daktarin, tinea root and pacify the conventional medication such as your glad stubborn dermatitis is clean).Observe two courses for the treatment of of treatment altogether.Curative effect determinate standard: recovery from illness: clinical symptoms and sign all disappear, and lab testing comprises fungal culture etc. and is feminine gender; Effective: clinical symptoms and sign all have clear improvement, and lab testing takes a turn for the better to some extent; Invalid: clinical symptoms and sign are all without improvement, and lab testing comprises fungal culture etc. and is the positive.(total effective rate=cure rate+obvious effective rate).Result is as shown in table 1:
Table 1: the observed and recorded result of experimental group and matched group personnel
This compound essential Oil is configured by Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae 7 kinds of main raw material of Chinese medicine and the pure plant extract quintessence oil of Fructus Dauci Sativae oil, Matricaria recutita quintessence oil, LVHUA 100,000 layers of quintessence oil and tea tree ethereal oil 4 kinds and forms.Fang Zhong, Radix Ampelopsis has effect of heat-clearing and toxic substances removing; Chinese tallow seed and Fructus Carpesii have the effect of parasite killing, diuretic; Fructus Dauci Sativae oil has the effect promoting cell regeneration; Matricaria recutita quintessence oil for pimples, herpes, eczema, tinea etc. have good therapeutical effect; LVHUA 100,000 layers of quintessence oil are used for cleaning a wound, and remove ulcer, acne; Tea tree ethereal oil improves the suppuration phenomenon of wound infection, and furuncle.Remove small pox and unclean position caused by chickenpox and herpes zoster.This compound essential Oil scientific formulation is reasonable, and rapidly, not containing pungent, experiment shows that products obtained therefrom total effective rate of the present invention is 98.9%, and successful is better than matched group in effect.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat a tea tree ethereal oil for epidermophytosis inguinale, it is characterized in that, be prepared from by following bulk drugs, be weight portion: Radix Ampelopsis 5-10; Chinese tallow seed 4-9; Herba Limnophilae rugosae 8-12; Fructus Carpesii 6-9; Fructus Crotonis 5-9; Flos Chrysanthemi Indici 9-15; Fructus Forsythiae 9-15; Fructus Dauci Sativae oil 5-8; Matricaria recutita quintessence oil 1.3-1.7; LVHUA 100,000 layers of quintessence oil 1.0-1.5; Tea tree ethereal oil 1.2-1.6.
2. a kind of tea tree ethereal oil for the treatment of epidermophytosis inguinale as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Radix Ampelopsis 6-9; Chinese tallow seed 5-8; Herba Limnophilae rugosae 9-11; Fructus Carpesii 7-8; Fructus Crotonis 6-8; Flos Chrysanthemi Indici 11-13; Fructus Forsythiae 11-13; Fructus Dauci Sativae oil 6-7; Matricaria recutita quintessence oil 1.4-1.6; LVHUA 100,000 layers of quintessence oil 1.1-1.4; Tea tree ethereal oil 1.3-1.5.
3. a kind of tea tree ethereal oil for the treatment of epidermophytosis inguinale as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Radix Ampelopsis 7.5; Chinese tallow seed 6.5; Herba Limnophilae rugosae 10; Fructus Carpesii 7.5; Fructus Crotonis 7; Flos Chrysanthemi Indici 12; Fructus Forsythiae 12; Fructus Dauci Sativae oil 6.5; Matricaria recutita quintessence oil 1.5; LVHUA 100,000 layers of quintessence oil 1.25; Tea tree ethereal oil 1.4.
4. a kind of tea tree ethereal oil for the treatment of epidermophytosis inguinale as described in as arbitrary in claim 1-3, it is characterized in that, preparation method is as follows:
(1) Radix Ampelopsis, Chinese tallow seed, Herba Limnophilae rugosae, Fructus Carpesii, Fructus Crotonis, Flos Chrysanthemi Indici and Fructus Forsythiae are together placed in thermostatic drying chamber dry, take out, be ground into fine powder, obtain mixed powder for subsequent use;
(2) step (1) gained mixed powder is placed in apparatus,Soxhlet's, add the ethanol that mass concentration is 80%, heating and refluxing extraction twice, first time reflux, extract, 1.2-1.8 hour, second time reflux, extract, 30-50 minute, merges extracted twice liquid, filter, distilling under reduced pressure, reclaims ethanol, obtains Chinese medicine oil;
(3) step (2) gained Chinese medicine oil is cooled to room temperature, adds Fructus Dauci Sativae oil, magnetic agitation 4-10 minute, and then add Matricaria recutita quintessence oil, LVHUA 100,000 layers of quintessence oil and tea tree ethereal oil while stirring, mix homogeneously, obtains compound essential Oil;
(4) by the sterilizing of above-mentioned gained quintessence oil, encapsulation, to obtain final product.
5. a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale according to claim 4, is characterized in that, temperature dry in step (1) is 43-57 DEG C (preferred dry temperature is 48-52 DEG C, and the temperature of the drying be more preferably is 50 DEG C).
6. a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale according to claim 4, it is characterized in that, time dry in step (1) is 35-50 minute (the preferred dry time is 40-45 minute, and the time of the drying be more preferably is 43 minutes).
7. a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale according to claim 4, it is characterized in that, the ethanol (preferably adding the ethanol of 5-7 times of mixed powder amount, the ethanol adding 6 times of mixed powder amounts be more preferably) of 4-8 times of mixed powder amount is added in step (2).
8. a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale according to claim 4, is characterized in that, reflux, extract, 1.4-1.6 hour first time in step (2) (preferably first time reflux, extract, 1.5 hours).
9. a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale according to claim 4, is characterized in that, second time reflux, extract, 35-45 minute (preferably second time reflux, extract, 40 minutes) in step (2).
10. a kind of preparation method for the treatment of the tea tree ethereal oil of epidermophytosis inguinale according to claim 4, is characterized in that, in step (3) magnetic agitation 6-8 minute (preferred magnetic agitation 7 minutes).
CN201510159427.0A 2015-04-07 2015-04-07 Tea tree essential oil for treating groin tinea and preparation method thereof Pending CN104800422A (en)

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