CN102552544B - Externally-used Chinese herba preparation for treating neurodermatitis and preparation method of same - Google Patents
Externally-used Chinese herba preparation for treating neurodermatitis and preparation method of same Download PDFInfo
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- CN102552544B CN102552544B CN 201210052711 CN201210052711A CN102552544B CN 102552544 B CN102552544 B CN 102552544B CN 201210052711 CN201210052711 CN 201210052711 CN 201210052711 A CN201210052711 A CN 201210052711A CN 102552544 B CN102552544 B CN 102552544B
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Abstract
The invention discloses an externally-used Chinese herba preparation for treating neurodermatitis and a preparation method of the externally-used Chinese herba preparation. According to weight ratio, materials preparing active ingredients of the externally-used Chinese herba preparation comprise cortex dictamni accounting for 40 g-100 g, cynanchum paniculatum accounting for 10 g-50 g, hemp kernels accounting for 15 g-70 g, dried radix rehmannia accounting for 30 g-100 g, cortex lycii radicis accounting for 30 g-90 g, fructus kochiae accounting for 40 g-90 g, cotton rose hibiscus leaves accounting for 30 g-90 g and menthol essences accounting for 6 g-15 g. The externally-used Chinese herba preparation has a quick effect and needs a short treatment course when being used for treating skin diseases such as pruritus and neurodermatitis, particularly has a rapid and obvious itching relieving effect, is free of allergy and drug resistance, has a better treatment effect on tinea corporis and tinea of feet and hands, and realizes a high cure rate with a low cost.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine for outer use for the treatment of neurodermatitis and preparation method thereof.
Background technology
In clinical common dermatosis, neurodermatitis occupies very most of, and characteristics are very to itch unbearably and be difficult to cure.At present, though be used for the treatment of this sick preparation have multiple, as Piyanping ointment, compound dexamethason acetate ointment etc., they are mostly Western medicine or chemicals, all exist the course for the treatment of long, though the fast drug withdrawal that takes effect is easily recurred and easily produces drug resistance, life-time service can have side effects to human body.Therefore, in order to give full play to the advantage of China's Chinese Traditional Medicine, seek a kind of effective Chinese medicine for outer use of neurodermatitis for the treatment of very necessary.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind ofly can effectively treat Chinese medicine for outer use of neurodermatitis and preparation method thereof.
For solving the problems of the technologies described above, the raw material of effective ingredient of the present invention forms and weight proportion is: Cortex Dictamni 40-100g, Radix Cynanchi Paniculati 10-50g, Fructus Cannabis 15-70g, Radix Rehmanniae 30-100g, Cortex Lycii 30-90g, the Fructus Kochiae 40-90g, Folium Hibisci Mutabilis 30-90g, Mentholum 6-15g.
Raw material composition and the weight proportion thereof of preferably making this effective ingredient are: Cortex Dictamni 60-90g, Radix Cynanchi Paniculati 20-40g, Fructus Cannabis 20-40g, Radix Rehmanniae 40-60g, Cortex Lycii 35-55g, the Fructus Kochiae 50-70g, Folium Hibisci Mutabilis 40-60g, Mentholum 8-12g.
Raw material composition and the weight proportion thereof of more preferably making this effective ingredient are: Cortex Dictamni 80g, Radix Cynanchi Paniculati 30g, Fructus Cannabis 30g, Radix Rehmanniae 50g, Cortex Lycii 45g, Fructus Kochiae 60g, Folium Hibisci Mutabilis 55g, Mentholum 10g.
The preparation method of Chinese medicine for outer use of the present invention comprises the following steps:
A, take Cortex Dictamni, Radix Cynanchi Paniculati, Fructus Cannabis, Radix Rehmanniae, Cortex Lycii, the Fructus Kochiae, Folium Hibisci Mutabilis by formula ratio, be ground into the following fine powder of 100 orders;
B, the fine powder of pulverizing is put into container, add ethanol 900ml-950ml of 70%, stir dipping 72h-96h, filter, dregs pressing, filtrate merges with press liquor, and standing 24h-36h filters, the collection filtrate for later use;
C, the Mentholum of formula ratio is dissolved in appropriate 70% ethanol;
D, above-mentioned two kinds of solution are mixed after, add sorbic acid 2g, then add 70% ethanol to 1000ml;
E, add sodium bicarbonate or hydrochloric acid solution in the above-mentioned mixed solution, transfer pH value to 6-8, sterilizing is the finished product externally applied liniment after canned.
The traditional Chinese medical science think neurodermatitis belong in the category of the style of work, wind being YANG-pathogen, the easiest impairment of YIN blood, treatment needs dispelling wind for relieving itching, removing pathogenic heat from blood and toxic substance from the body.In Chinese medicine for outer use of the present invention, Cortex Dictamni, Fructus Kochiae dispelling wind for relieving itching are monarch drug, and " book on Chinese herbal medicine is original " said: accumulated heat in Fructus Kochiae master skin; " property of medicine opinion " said: all pyretic toxicity wind of Cortex Dictamni master.Folium Hibisci Mutabilis, Cortex Lycii, Radix Cynanchi Paniculati detoxifcation heat clearing away are ministerial drug, and Compendium of Material Medica is said: the Folium Hibisci Mutabilis removing pathogenic heat from blood and toxic substance from the body; " pearl sac " said: Cortex Lycii is blood-cooling drugs." Chinese materia medica " said: the Radix Cynanchi Paniculati dispelling wind for relieving itching.Radix Rehmanniae, Fructus Cannabis removing heat from blood YIN nourishing are adjuvant drug, and " Chinese materia medica " said: Radix Rehmanniae is phencyclidine, and Compendium of Material Medica is said: Fructus Cannabis is nourshing Yin and drynsessmoistening prescription.Mentholum is transdermal agent for making medicine, the through medicine of priming institute.Full side's compatibility is reasonable, evident in efficacy.
Because the present invention is pure Chinese medicinal preparation, without any side effects to the patient, easy to use, drug cost is low, to treatment skin pruritus, the dermatosis instant effects such as neurodermatitis, short treating period, particularly antipruritic effect is obvious rapidly, allergy and Drug resistance can not occur, and tinea corporis and tinea manus and pedis are also had better effects.Medicine of the present invention is through carrying out clinical observation to 100 routine neurodermatitis patients, and total effective rate can reach 98%.
The specific embodiment
Embodiment one:
The Chinese medicine for outer use for the treatment of neurodermatitis, the raw material of its effective ingredient forms and weight proportion is: Cortex Dictamni 60g, Radix Cynanchi Paniculati 40g, Fructus Cannabis 20g, Radix Rehmanniae 100g, Cortex Lycii 90g, Fructus Kochiae 50g, Folium Hibisci Mutabilis 90g, Mentholum 6g.
Embodiment two:
The Chinese medicine for outer use for the treatment of neurodermatitis, the raw material of its effective ingredient forms and weight proportion is: Cortex Dictamni 100g, Radix Cynanchi Paniculati 50g, Fructus Cannabis 70g, Radix Rehmanniae 40g, Cortex Lycii 55g, Fructus Kochiae 90g, Folium Hibisci Mutabilis 60g, Mentholum 8g.
Embodiment three:
The Chinese medicine for outer use for the treatment of neurodermatitis, the raw material of its effective ingredient forms and weight proportion is: Cortex Dictamni 40g, Radix Cynanchi Paniculati 10g, Fructus Cannabis 15g, Radix Rehmanniae 30g, Cortex Lycii 30g, Fructus Kochiae 70g, Folium Hibisci Mutabilis 40g, Mentholum 15g.
Embodiment four:
The Chinese medicine for outer use for the treatment of neurodermatitis, the raw material of its effective ingredient forms and weight proportion is: Cortex Dictamni 90g, Radix Cynanchi Paniculati 20g, Fructus Cannabis 40g, Radix Rehmanniae 60g, Cortex Lycii 35g, Fructus Kochiae 40g, Folium Hibisci Mutabilis 30g, Mentholum 12g.
Embodiment five:
The Chinese medicine for outer use for the treatment of neurodermatitis, as preferred side, the raw material of its effective ingredient forms and weight proportion is: Cortex Dictamni 80g, Radix Cynanchi Paniculati 30g, Fructus Cannabis 30g, Radix Rehmanniae 50g, Cortex Lycii 45g, Fructus Kochiae 60g, Folium Hibisci Mutabilis 55g, Mentholum 10g.
The preparation method of Chinese medicine for outer use of the present invention comprises the following steps:
A, take Cortex Dictamni, Radix Cynanchi Paniculati, Fructus Cannabis, Radix Rehmanniae, Cortex Lycii, the Fructus Kochiae, Folium Hibisci Mutabilis by above-described embodiment, be ground into the following fine powder of 100 orders;
B, the fine powder of pulverizing is put into container, add ethanol 900ml-950ml of 70%, stir dipping 72h-96h, filter, dregs pressing, filtrate merges with press liquor, and standing 24h-36h filters, the collection filtrate for later use;
C, the Mentholum of formula ratio is dissolved in appropriate 70% ethanol, amount of alcohol is 10 ml;
D, above-mentioned two kinds of solution are mixed after, add sorbic acid 2g, then add 70% ethanol to 1000ml;
E, add sodium bicarbonate or hydrochloric acid solution in the above-mentioned mixed solution, transfer pH value to 6-8, sterilizing is the finished product externally applied liniment after canned.
The present invention is pure Chinese medicinal preparation, and is without any side effects to the patient, easy to use, and drug cost is low, to treatment skin pruritus, the dermatosis instant effects such as neurodermatitis, short treating period, particularly antipruritic effect is obvious rapidly, allergy and Drug resistance can not occur, and tinea corporis and tinea manus and pedis are also had better effects.Medicine of the present invention carries out clinical observation on the therapeutic effect to 100 routine different skin patients, and total effective rate reaches 98%.100 routine patients are divided into treatment group and matched group at random, and wherein treatment group and matched group are respectively 50 examples.
1, treatment group: 50 examples, with this product wiping affected part, every day 4 times.
2, matched group: 50 examples, with PIYANPING wiping affected part, every day 4 times.
Be for 2 weeks the course for the treatment of, therapeutic outcome is as follows:
| Group | Number of cases | Produce effects (%) | Effectively (%) | Invalid (%) | Effective percentage (%) |
| Treatment group | 50 | 29 （58） | 20（40） | 1? (2)? | 49? (98) |
| Matched group | 50 | 20? (40) | 18 (36) | 12? (24) | 38? (76) |
Result shows: this product therapeutic outcome total effective rate reaches 98%, has compared significant difference with matched group, P ﹤ 0.01.
Claims (4)
1. Chinese medicine for outer use for the treatment of neurodermatitis, the raw material composition and the weight proportion thereof that it is characterized in that this Chinese medicine for outer use effective ingredient are: Cortex Dictamni 40-100g, Radix Cynanchi Paniculati 10-50g, Fructus Cannabis 15-70g, Radix Rehmanniae 30-100g, Cortex Lycii 30-90g, the Fructus Kochiae 40-90g, Folium Hibisci Mutabilis 30-90g, Mentholum 6-15g.
2. the Chinese medicine for outer use for the treatment of neurodermatitis according to claim 1, the raw material composition and the weight proportion thereof that it is characterized in that this Chinese medicine for outer use effective ingredient are: Cortex Dictamni 60-90g, Radix Cynanchi Paniculati 20-40g, Fructus Cannabis 20-40g, Radix Rehmanniae 40-60g, Cortex Lycii 35-55g, the Fructus Kochiae 50-70g, Folium Hibisci Mutabilis 40-60g, Mentholum 8-12g.
3. the Chinese medicine for outer use for the treatment of neurodermatitis according to claim 2, the raw material composition and the weight proportion thereof that it is characterized in that this Chinese medicine for outer use effective ingredient are: Cortex Dictamni 80g, Radix Cynanchi Paniculati 30g, Fructus Cannabis 30g, Radix Rehmanniae 50g, Cortex Lycii 45g, Fructus Kochiae 60g, Folium Hibisci Mutabilis 55g, Mentholum 10g.
4. the preparation method of the Chinese medicine for outer use of according to claim 1-3 described treatment neurodermatitiss of any one is characterized in that comprising the following steps:
A, take Cortex Dictamni, Radix Cynanchi Paniculati, Fructus Cannabis, Radix Rehmanniae, Cortex Lycii, the Fructus Kochiae, Folium Hibisci Mutabilis by formula ratio, be ground into the following fine powder of 100 orders;
B, the fine powder of pulverizing is put into container, add ethanol 900ml-950ml of 70%, stir dipping 72h-96h, filter, dregs pressing, filtrate merges with press liquor, and standing 24h-36h filters, the collection filtrate for later use;
C, the Mentholum of formula ratio is dissolved in appropriate 70% ethanol;
D, above-mentioned two kinds of solution are mixed after, add sorbic acid 2g, then add 70% ethanol to 1000ml;
E, add sodium bicarbonate or hydrochloric acid solution in the above-mentioned mixed solution, transfer pH value to 6-8, sterilizing is the finished product externally applied liniment after canned.
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| CN103071127A (en) * | 2013-01-05 | 2013-05-01 | 马长林 | Traditional Chinese medicine for curing psoriasis and preparation method thereof |
| CN104523991A (en) * | 2014-12-20 | 2015-04-22 | 钱家美 | Traditional Chinese medicinal liniment for treating neurodermatitis |
| CN105749645B (en) * | 2016-03-30 | 2018-09-14 | 刘晓冰 | A kind of pest-resistant type air purifier filter device and its installation and application method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1172674A (en) * | 1997-08-29 | 1998-02-11 | 刘进成 | Chinese medicinal herb composition for treating skin disease |
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| CN101116691A (en) * | 2007-08-29 | 2008-02-06 | 北京艺信堂医药研究所 | Chinese traditional medicine composition for treating neurodermatitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1172674A (en) * | 1997-08-29 | 1998-02-11 | 刘进成 | Chinese medicinal herb composition for treating skin disease |
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