CN104784539A - Traditional Chinese medicine for treating chronic periodontitis - Google Patents
Traditional Chinese medicine for treating chronic periodontitis Download PDFInfo
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- CN104784539A CN104784539A CN201510193530.7A CN201510193530A CN104784539A CN 104784539 A CN104784539 A CN 104784539A CN 201510193530 A CN201510193530 A CN 201510193530A CN 104784539 A CN104784539 A CN 104784539A
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Abstract
The invention relates to a traditional Chinese medicine for treating chronic periodontitis. The traditional Chinese medicine is prepared from the following crude drugs in parts by weight: 15 parts of honeysuckle stem, 15 parts of rhizoma cimicifugae, 12 parts of houttuynia cordata, 15 parts of coptis chinensis, 12 parts of moutan bark, 10 parts of rhizoma phragmitis, 10 parts of radix rehmanniae recens and 6 parts of angelica sinensis. The clinical experiment shows that the traditional Chinese medicine can be used for safely and effectively treating chronic periodontitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of chronic periodontitis.
Background technology
Chronic periodontitis is one of common oral disease, and it not only can cause the symptom such as halitosis, gingival hemorrhage to affect minimal invasive treatment, work, and easy protracted course of disease, recurrent exerbation and then cause frontal resorption, loss of tooth.Modern medicine combines periodental non-surgical treatment to it mainly with antibiotics, and curative effect is good but the untoward reaction of antibiotics prolonged application is more, and easily produce drug resistance, curative effect reduces gradually.Chronic periodontitis is many because the pathogenic bacterium such as anaerobe, gingiva bacteroid, product melanin bacillus are because of reason prolonged stay, attachments such as tartar, food impaction, dental plaques, and local gingivitis reaction, appears in antibacterial amount reproduction, slow progress, recurrent exerbation, bacterial plaque is in progress under gingivally gum, destroys periodontal collagen, epithelial cell, cause gingiva attachment loss, form periodontal pocket, destroy alveolar bone, have a strong impact on minimal invasive treatment, work, finally cause loss of tooth, impact pronunciation, masticatory function.Eliminate pathogenic bacterium and be detained environment, suppressing local inflammatory response, is the key effectively suppressing chronic periodontitis to be in progress.Periodental non-surgical treatment is the main measure eliminating pathogenic bacterium delay environment, it is scraped to control by local and removes paraplasm tissue in periodontal pocket, alveolar bone is suitably repaired, be beneficial to periodontal adhere to again, alleviate periodontal damage, successive elimination periodontal pocket, but its pain is comparatively violent, need carry out under good analgesia, avoid making patients's psychological burden.
Medical material present Research involved in the present invention is as follows:
Caulis Lonicerae [another name] Radix Ophiopogonis, Caulis Lonicerae, Caulis Lonicerae.[source] this product is the dry stem branch of caprifoliaceae plant Radix Ophiopogonis.Autumn, season in winter two tap, and dry.[nature and flavor] are sweet, cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, beriberoid pyretic arthralgia, redness and swelling of joints burning pain.[usage and dosage] takes orally: decoct soup, 9 ~ 30g.[attention] Deficiency and coldness of spleen and stomach, more than person that has loose bowels is forbidden.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Cimicifugae [another name] Radix Longan, hole root of the tooth.[source] Chinese medicine Rhizoma Cimicifugae is the rhizome of Ranunculaceae herbaceos perennial SANYE Rhizoma Cimicifugae or Cimicifuga Dahurica or Rhizoma Cimicifugae.[nature and flavor] are pungent, sweet, are slightly cold.[return through] returns lung, spleen, large intestine, stomach warp.[function cures mainly] delivers rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, measles is not smooth, toothache aphtha, laryngopharynx swelling and pain, visceroptosis.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[attention] yang deficiency sun is floating, and dyspnea with fullness of the chest QI rising in reverse order and measles thoroughly person avoid use.Elevate a turnable ladder yang-energy should with processing Rhizoma Cimicifugae.[extracts] " China's book on Chinese herbal medicine ".
Herba Houttuyniae [another name] Herba Houttuyniae, hog snout hole, Herba rutae, fish scale grass.[source] this product is the dry aerial parts of saururaceae plant houttuynia cordata.Tap when the luxuriant spica of stem and leaf in summer is many, removing impurity, dries.[nature and flavor] are pungent, are slightly cold.[return through] returns lung meridian.[function cures mainly] heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.[usage and dosage] takes orally: decoct soup, 15 ~ 25g, should not decoct for a long time.[attention] deficiency-cold symptoms and negative outer infections avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Coptidis [another name] Rhizoma Coptidis, Jiang Lian, Rhizoma Coptidis.[source] herbaceos perennial, happiness cools, moistening part, belongs to Ranunculaceae Coptis.[nature and flavor] (root) is bitter, cold, nontoxic.[return through] GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.[usage and dosage] takes orally: decoct soup, 2 ~ 5g.[attention] this product large bitter Great Cold, cross clothes and take injuring spleen-stomach for a long time, Deficiency and coldness of spleen and stomach person avoids use.Bitter dry impairment of body fluid, deficiency of YIN Tianjin the wounded is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Cortex Moutan [another name] Cortex Moutan, unpeeled CORTEX MOUTAN, wooden Radix Paeoniae, bar Cortex Moutan, Luoyang flower.[source] this product is the dry root bark of ranunculaceae peony.Autumn excavates root, and removing radicula, strips root bark, dry.[nature and flavor] are bitter, pungent, are slightly cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.[usage and dosage] takes orally: decoct soup, 6-12g.[attention] blood deficiency has cold, anemia of pregnant woman and the careful clothes of menorrhagia person.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Phragmitis [another name] reed root, reed head.[source] this product is the fresh of grass phragmites communis or dry rhizome.The whole year all can excavate, removing bud, fibrous root and membranaceous leaf, using fresh herb or dry.[nature and flavor] are sweet, cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[attention] because of the cold cholera fight of steps on the eastern side of the hall where the host stood to welcome the guests swollen, tell because of vomiting due to pathogenic cold and do not take.[extracts] " China's book on Chinese herbal medicine ".
The Radix Rehmanniae [another name] Radix Rehmanniae, marrow, sun essence, benzyl root, milk daughter root, Canis familiaris L. milk daughter root, grandmother's milk root, mountain cigarette root, mountain tobacco Radix Rehmanniae medical material root, mountain cigarette root, Chinese cabbage root, wine pot flower root, wine cup cup flower root, a sweet wine root, a honey jar root, the Radix Rehmanniae, Radix Rehmanniae, the little Radix Rehmanniae, dry Radix Rehmanniae, Huai Radix Rehmanniae, Radix Rehmanniae.The dried root that [source] is scrophulariaceae rehmannia glutinosa plant.[nature and flavor] sweet in the mouth, hardship, cold nature.[return through] GUIXIN, liver, kidney channel.Matter profit is fallen and is let out.[function cures mainly] clearing away heat and cooling blood, to join the army blood for warm febrile disease, high fever coma, xerostomia crimson tongue.Control the convalescent stage of febrile disease, waste heat not to the greatest extent, hinder, night fever abating at dawn, red tongue rapid pulse person by cloudy liquid.Can be used for controlling warm febrile disease to join the army blood, heat in blood poison is contained, and hematemesis and epistaxis, macule purple is black.It is thirsty that YIN nourishing and the production of body fluid promoting effect is used for Tianjin wound, and interior-heat is quenched one's thirst.Control epidemic febrile disease impairment of YIN, dryness of the intestine constipation.[usage and dosage] takes orally: decoct soup, 10 ~ 30g.[attention] is cold in nature and stagnant, and damp-retention due to hypofunction of the spleen abdominal distention loose stool person, should not use.[extracts] " China's book on Chinese herbal medicine ".
Radix Angelicae Sinensis [another name] is dry returns.[source] this product is the dry root of umbelliferae angelica.Autumn end excavates, and removing fibrous root and silt, after moisture slightly evaporates, be bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.[usage and dosage] takes orally: decoct soup, 10 ~ 25g.[attention] dampness fullness in the epigastrium and abdomen and the careful clothes of diarrhea with loose stool person.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of chronic periodontitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic periodontitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of chronic periodontitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Caulis Lonicerae 15 parts, Rhizoma Cimicifugae 15 parts, Herba Houttuyniae 12 parts, Rhizoma Coptidis 15 parts, Cortex Moutan 12 parts, Rhizoma Phragmitis 10 parts, 10 parts, the Radix Rehmanniae, Radix Angelicae Sinensis 6 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and chronic periodontitis 130 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 65 example and matched group 65 example at random, treatment group man 39 example, female 26 example, 43 ~ 67 years old age, 53 years old mean age; Matched group man 41 example, female 24 example, 42 ~ 68 years old age, 60 years old mean age, the course of disease 1 ~ 9 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national chronic periodontitis clinical speciality: (1) has halitosis, gingiva pain, the symptom such as hemorrhage; (2) periodontal inspection can find gingiva inflammatory edema, pyorrhea, gum retracted nipple, odontoseisis, displacement; (3) spy examines discovery attachment loss, degree of depth > 3mill; (4) x line sheet has frontal resorption Imageology; (5) implication heat is smelly, red tongue with yellow fur, likes cold aversion to heat, dry mouth and tougue, slippery and rapid pulse, dialectical genus stomach excessive heat.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.One month course for the treatment of.
Matched group oral tinidazole tablets 0.5g/ time, 2 times/day, one month course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: the clinical symptoms such as halitosis, gingiva pain, hemorrhage, red and swollen, pyorrhea all disappears, and tooth mobility improves more than I degree, and gingival atrophy is not in progress;
Effective: the symptoms such as gingiva pain disappears, hemorrhage, red and swollen, pyorrhea obviously alleviate, and tooth mobility makes moderate progress, and gingival atrophy is not in progress;
Invalid: not meet above-mentioned condition.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment chronic periodontitis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Caulis Lonicerae 15 grams, Rhizoma Cimicifugae 15 grams, Herba Houttuyniae 12 grams, Rhizoma Coptidis 15 grams, Cortex Moutan 12 grams, Rhizoma Phragmitis 10 grams, 10 grams, the Radix Rehmanniae, Radix Angelicae Sinensis 6 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of chronic periodontitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Caulis Lonicerae 15 grams, Rhizoma Cimicifugae 15 grams, Herba Houttuyniae 12 grams, Rhizoma Coptidis 15 grams, Cortex Moutan 12 grams, Rhizoma Phragmitis 10 grams, 10 grams, the Radix Rehmanniae, Radix Angelicae Sinensis 6 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of chronic periodontitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Caulis Lonicerae 15 grams, Rhizoma Cimicifugae 15 grams, Herba Houttuyniae 12 grams, Rhizoma Coptidis 15 grams, Cortex Moutan 12 grams, Rhizoma Phragmitis 10 grams, 10 grams, the Radix Rehmanniae, Radix Angelicae Sinensis 6 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of chronic periodontitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of chronic periodontitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Caulis Lonicerae 15 parts, Rhizoma Cimicifugae 15 parts, Herba Houttuyniae 12 parts, Rhizoma Coptidis 15 parts, Cortex Moutan 12 parts, Rhizoma Phragmitis 10 parts, 10 parts, the Radix Rehmanniae, Radix Angelicae Sinensis 6 parts.
2. a kind of Chinese medicine for chronic periodontitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Caulis Lonicerae 15 parts, Rhizoma Cimicifugae 15 parts, Herba Houttuyniae 12 parts, Rhizoma Coptidis 15 parts, Cortex Moutan 12 parts, Rhizoma Phragmitis 10 parts, 10 parts, the Radix Rehmanniae, Radix Angelicae Sinensis 6 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of chronic periodontitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Caulis Lonicerae 15 parts, Rhizoma Cimicifugae 15 parts, Herba Houttuyniae 12 parts, Rhizoma Coptidis 15 parts, Cortex Moutan 12 parts, Rhizoma Phragmitis 10 parts, 10 parts, the Radix Rehmanniae, Radix Angelicae Sinensis 6 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of chronic periodontitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Caulis Lonicerae 15 parts, Rhizoma Cimicifugae 15 parts, Herba Houttuyniae 12 parts, Rhizoma Coptidis 15 parts, Cortex Moutan 12 parts, Rhizoma Phragmitis 10 parts, 10 parts, the Radix Rehmanniae, Radix Angelicae Sinensis 6 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1654056A (en) * | 2004-02-10 | 2005-08-17 | 湖北丽益医药科技有限公司 | Chinese medicine composition for peridentitis and preparing method thereof |
| CN102423428A (en) * | 2011-12-13 | 2012-04-25 | 赵丹 | Chinese medicine composition for treating periodontitis |
-
2015
- 2015-04-16 CN CN201510193530.7A patent/CN104784539A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1654056A (en) * | 2004-02-10 | 2005-08-17 | 湖北丽益医药科技有限公司 | Chinese medicine composition for peridentitis and preparing method thereof |
| CN102423428A (en) * | 2011-12-13 | 2012-04-25 | 赵丹 | Chinese medicine composition for treating periodontitis |
Non-Patent Citations (3)
| Title |
|---|
| 李元聪: "清胃散加味治疗急性牙源性感染204例报告", 《中国中医急症》 * |
| 温映萍等: "自拟清胃汤加减治疗成人牙周炎临床观察", 《中医药学刊》 * |
| 罗芳国: "辨证分型治疗牙周病268例疗效观察", 《湖南中医杂志》 * |
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Application publication date: 20150722 |