CN104784398B - The external-applied ointment and preparation method thereof for treating apoplexy sequelae - Google Patents
The external-applied ointment and preparation method thereof for treating apoplexy sequelae Download PDFInfo
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Abstract
A kind of external-applied ointment and preparation method thereof for treating apoplexy sequelae, ointment are 100 parts of camphor to be added, made of 1000 parts of vaseline by the extract of the prepared slices of Chinese crude drugs of 10 parts of quality extracting honeysuckle, 15 parts of cordate houttuynia, 10 parts of subprostrate sophora, 10 parts of rheum officinale, 10 parts of Radix Glycyrrhizae, 10 parts of the seed of cowherb, 15 parts of rhizoma typhonii, 10 parts of camphor, 20 parts of Radix Astragali, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of bombyx batryticatus, 10 parts of scorpio, 15 parts of pheretima, 15 parts of uncaria.When production, the mixture of the prepared slices of Chinese crude drugs is added in ethyl alcohol and is impregnated 15 days, liquid will be bubbled out and poured out, remaining Chinese medicine is put in boiler to be steamed 2 hours under 100 °C of environment, and the supernatant in above two step is purified respectively and drains liquid, obtains the pure powder of Chinese medicine；Vaseline is fallen and is boiled in pot, the pure powder of Chinese medicine is put into and mixes, camphor is put into when cooling to 45 °C and mixes, ointment is made.The present invention is external-applied ointment, avoids the pain and worry of patient's body, in turn avoids side effect of the drug to internal organs official, is treated simple, significant in efficacy.Preparation method is simple and reliable, can easily prepare required ointment.
Description
Technical field:
The present invention relates to a kind of external-applied ointments and preparation method thereof for treating apoplexy sequelae.
Background technique:
Apoplexy sequelae, also known as hemiplegia, hemiplegia.A name of disease that apoplexy is traditional Chinese medicine and people are to acute
The general designation of cranial vascular disease.It accurately can visually reflect very much the morbidity state and process of disease, the speed of disease development
Degree be rapidly, this disease be from suddenly faint, the senseless, distortion of commissure that occurs together, dysphonia, hemiplegia or without fainting
It is a kind of disease of cardinal symptom at stupor.Apoplexy includes the cerebral hemorrhage of modern medicine, subarachnoid hemorrhage, cerebral infarction, short
Temporary cerebral ischemia attack etc..Because this kind of disease onset is hurried, breaking with tremendous force, change of illness state is rapid, as the wind of nature, ancient times
The thinking of medical use analogy and be named as " apoplexy ", suddenly because of its morbidity, also known as cerebrovascular accident.Apoplexy is newly sent out every year in China
About 2,200,000 people of patient, about 1,000,000 people of the patient for dying of cerebrovascular disease every year, patient's number (including recovery from illness) of existence are 600-
7000000 people, cerebrovascular disease are the very high diseases of disability rate.According to statistics, in the cerebrovascular patient of survival, there are about 25% different journeys
Degree ground disability, wherein severe disabled person accounts for about 40%.About 30,000,000 people of the annual neopathy in the whole world.General morbidity
Age was in 50 years old or more disease incidence highest.The people that the people of 30-40 years old or so recent years suffers stroke also is increasing, and have by
Cumulative more trend.Apoplexy is a kind of relatively high common disease of the whole world death rate, and the treatment of apoplexy sequelae is the whole world
The big problem faced.
The Western medicine of traditional treatment cerebral hemorrhage disease has adona, fibrin ferment, Trostin M, Reptilase etc..In order to which brain is gone out as early as possible
Blood stops, and quantity is all very big, after brain not bleeding, and brings serious cerebral thrombosis.Using the drug of cerebral thrombosis
Have ahylysantinfarctase, calciparine, Lumbrokinase, streptokinase, brain blood logical, aspirin, it is glad cut down it sting, the medicines such as Folium Ginkgo.Have
Cerebral thrombosis patient eats aspirin for a long time, finally results in the dirty organ hemorrhage such as cerebral hemorrhage and dental hemorrhage.Long-term Oral is glad to be cut down it and stings
Hepatorenal damage can also be caused.Tcm therapy is oral traditional Chinese medicine decoction of medicinal ingredients or Chinese patent drug.Such as: xiaoshuan tongluo tablet, anti-embolism regenerative pill, hemiplegia
Restoration pill etc..Some application acupuncture-therapies, curative effect length are unsatisfactory.By long-term western medicines in treatment apoplexy sequelae, not
Have and obtains satisfied curative effect.Acute stroke patients there is also serious complication, such as hernia cerebri, hemorrhage of digestive tract, respiratory tract sense
Dye, bedsore etc..Chronic patient is taken medicine for a long time causes hepatorenal damage, and serious patient can cause a series of complication such as total paralysis.
Summary of the invention:
The object of the present invention is to provide a kind of external-applied ointment and preparation method thereof for treating apoplexy sequelae, acute brain goes out
Blood, cerebral thrombosis and patients with cerebral infarction are generally rescued one month or so in hospital, etc. after stable diseases again with this medicinal ointment therapy,
It allows apoplexy sequelae patient not take medicine, not have an injection, not acupuncture-moxibustion, avoids the pain and worry of patient's body, in turn avoid drug pair
The side effect of internal organs official is treated simple, significant in efficacy.Preparation method is simple, it is reliable, be easily mastered.
The purpose of the present invention is what is realized as follows: the external-applied ointment of the treatment apoplexy sequelae is taken by quality
10 parts of honeysuckle (honeysuckle), 15 parts of cordate houttuynia, 10 parts of subprostrate sophora, 10 parts of rheum officinale (Sichuan troops), 10 parts of Radix Glycyrrhizae, 10 parts of the seed of cowherb,
15 parts of rhizoma typhonii, 10 parts of camphor (cinnamomum camphora brain), 20 parts of Radix Astragali, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of bombyx batryticatus, 10 parts of scorpio (full worm), pheretima 15
Part, 15 parts of uncaria of the prepared slices of Chinese crude drugs, 100 parts of camphor is added in obtained extract, ointment made of 1000 parts of vaseline.
The method of the external-applied ointment of the above treatment apoplexy sequelae of preparation, is that the mixture of the prepared slices of Chinese crude drugs is added to 2 times
It is impregnated 15 days in 95% ethyl alcohol of quality, stirring is primary daily, will bubble out liquid and pours out, and remaining Chinese medicine is put in boiler at 100 °C
It is steamed 2 hours under environment, the supernatant in above two step is purified respectively and drains liquid, obtain the pure powder of Chinese medicine；Vaseline is fallen
It is boiled in pot, is put into the pure powder of Chinese medicine and mixes, be put into camphor when cooling to 45 °C and mix, ointment is made.
Fang Xie: honeysuckle, cordate houttuynia, rheum officinale, subprostrate sophora are clearing heat and detoxicating, heat dissipation, and disappear paralysis excretion.It is camphor, the seed of cowherb, white
Monkshood, uncaria dredging collateral and promoting blood circulation, stagnation resolvation, detoxicating and resolving a mass correct apoplexy facial paralysis.Radix Astragali, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae tonifying Qi, blood pressure lowering promote
Restore function into nerve cell.Bombyx batryticatus, scorpio, pheretima softening hard masses dissolving stasis, walk to wear steepest, can search that pick network oblique deeply with gap, it is logical to grow liquid
Network.Camphor has mild stimulation and antisepsis to skin.It has firmly embrocated and has sent out effect red, there are also slight anesthetic effects, excited
The nervous centralis of whole body, it is especially pronounced for high-level center, it promotes blood circulation and cardiac effect, the function of being conducive to whole body is multiple
Soviet Union.Full side is using activating microcirculation and removing stasis medicinal, dispelling wind and removing obstruction in the meridians as objective, and blood stasis must be changed, and skew wind must dispel, and train of thought reconciles, and blood flow is unimpeded, and muscle must support,
Therefore satisfactory effect.
Skin irritation test: 32 kilograms of White Rabbits are taken, respectively shave off back hair.Ointment respectively with preparation is daily
It whitewashes rabbit back 30 minutes outside, is used in conjunction 30 days, it is red to rub heat stranding with the hands.Observation in every 24 hours is three times.Continuous apply rubs observation in 30 days with the hands.White rabbit skin
Skin stimulation test the result is that: without red and swollen, exudation, go out the phenomenon that bubble and occur, be no different paradoxical reaction.Prove that this ointment is pierced without skin
Swash reaction, non-toxic reaction.
Treatment method: external-applied ointment treats apoplexy sequelae patient.Mainstay cream embrocates back, from seventh cervical spine rub with the hands to
Thoracic lumbar vertebrae sacral is that center column embrocates ointment.Critically ill patient can also increase according to the state of an illness embrocates chest, abdomen and four limbs
Position.After generally embrocating uniformly, irradiated 20 minutes with 75 °C of infrared therapy apparatus, once a day, 30 days as one therapeutic course is generally controlled
Until treating three months.
The diagnostic criteria of apoplexy sequelae:
Computed tomography brain scan, to stroke diagnosis 100%, to 85% or more ischemic apoplexy sequela diagnosis, after apoplexy 24 hours
It diagnoses clear.
Blood sugar urinary sugar measurement, the treatment and prognosis of apoplexy sequelae are very big with blood glucose relationship.Fasting blood-glucose is more than
11.12mmoL/L.Show that damage of hypothalamus is serious, the death rate is high.
40 minutes processes of magnetic resonance MRI diagnose more acurrate.
Eosinophil count, the state of an illness is heavier, and acidophil is fewer.
Effect for the treatment of sequela of apoplexy standard:
Healing: patient clinical symptom disappears, and restores normal through CT check brain tissue, muscle strength reaches IV-V grades, individual
It takes care of oneself, it is handsome.
Effective: the clinical symptoms of patient completely disappear, and CT examination is normal, and II-III grade of muscular strength, personal care.
Improve: patient clinical symptom is obviously improved, CT examination abnormal signal weaken, face, language and swallowed it is obviously good
Turn.Upper and lower extremities functional rehabilitation 60%, muscular strength reach I grades, and personal care is difficult.
Invalid: after clinical treatment, clinical symptoms, which do not occur any symptom, to be improved.
Clinical trial:
(1) treatment group: applying medicinal ointment therapy apoplexy sequelae, and treatment is primary daily, and continuous treatment three months are limitation.Closely
Over 3 years be total to treatment 496 apoplexy after disease patient, wherein Aeg 400, aeg 96, the age -75 years old 50 years old it
Between.109 are cured, cure rate 22%；Effective 123, obvious effective rate 24.8%；It improves 228, improvement rate 46%；Invalid 36, nothing
Efficiency 7.26%.Total effective rate is 92.7%
(2) control group: selection areal apoplexy sequelae patient 60, the age is between 50-70 years old.Male 45,
Women 15, be limitation using hospital's western medicines in treatment three months.8 are cured, cure rate 13.3%；Effective 15, obvious effective rate
25%；It improves 13, improvement rate 21.66%；Invalid 24, inefficiency 40%.Total effective rate is 60%
Statistical result: control group and treatment group's significant difference.
The results show: external-applied ointment treats apoplexy sequelae, and document has no similar report at home, in external-applied ointment
There are following six kinds of discoveries in treatment patient procedure:
(1) apoplexy sequelae patient makes human body improve immunity, flu, fever under the outside stimulus of external-applied ointment
Disease incidence substantially reduce.
(2) outside stimulus has clearing heat and detoxicating, anti-inflammatory, antibacterial, inflammation extinction tests, and blood laboratory leukocyte restores normal.
(3) the natural protection ability of body has been transferred in excitation, repairs power, many disappearance of disease existing for other human bodies.
(4) by skin irritatin, pituitary is had activated, hormonal secretion is changed, thus make the reproductions such as impotence, premature ejaculation
System illness is improved.
(5) external-applied ointment has auxiliary therapeutic action to the disease other than apoplexy sequelae.
(6) Chinese medicine lotion for external use does not damage six mansion organ of human body the five internal organs, has prevented to destroy human body because of drug side-effect
Interior environment.
The present invention is external-applied ointment, pure Chinese medicine ingredient, and when treatment allows apoplexy sequelae patient not take medicine, not have an injection, not needle
Toast, avoids the pain and worry of patient's body, in turn avoids side effect of the drug to internal organs official, treats simple, significant in efficacy.System
Preparation Method is simple and reliable, can easily prepare required ointment.
Specific embodiment:
Embodiment 1
Extracting honeysuckle 10g, cordate houttuynia 15g, subprostrate sophora 10g, rheum officinale 10g, Radix Glycyrrhizae 10g, seed of cowherb 10g rhizoma typhonii
15g, camphor 10g, Radix Astragali 20g, Radix Salviae Miltiorrhizae 10g, bombyx batryticatus 10g, scorpio 10g, pheretima 15g, the uncaria 15g prepared slices of Chinese crude drugs and camphor
100g, vaseline 1000g.It is put into 95% ethyl alcohol of 2 times of quality and is impregnated 15 days with Chinese medicine crude drug, stirring is primary daily, will bubble out
Liquid is poured out, and remaining Chinese medicine, which is put, to be steamed 2 hours under 100 °C of environment in boiler, and supernatant Chinese medicine twice you can well imagine and pure drain liquid
Body obtains the pure powder of Chinese medicine.Vaseline is fallen and is boiled in pot, the pure powder of Chinese medicine is put into and mixes, cooling is put into camphor to 45 °C and mixes, and obtains medicine
Cream dispenses spare.
Embodiment 2
Extracting honeysuckle 10kg, cordate houttuynia 15kg, subprostrate sophora 10kg, rheum officinale 10kg, Radix Glycyrrhizae 10kg, seed of cowherb 10kg are white
Monkshood 15kg, camphor 10kg, Radix Astragali 20kg, Radix Salviae Miltiorrhizae 10kg, bombyx batryticatus 10kg, scorpio 10kg, pheretima 15kg, uncaria 15kg Chinese medicine drink
Piece and camphor 100kg, vaseline 1000kg.It is put into 95% ethyl alcohol of 340kg and is impregnated 15 days with Chinese medicine crude drug, stir one daily
It is secondary, liquid will be bubbled out and poured out, remaining Chinese medicine is put in boiler to be steamed 2 hours under 100 °C of environment, and supernatant Chinese medicine twice is distinguished
Liquid is drained in purification, obtains the pure powder of Chinese medicine.Vaseline is fallen and is boiled in pot, the pure powder of Chinese medicine is put into and mixes, cool and be put into camphor tree to 45 °C
Brain mixes, and obtains ointment, dispenses spare.
Claims (2)
1. a kind of external-applied ointment for treating apoplexy sequelae, it is characterised in that: be by 10 parts of quality extracting honeysuckle, cordate houttuynia 15
Part, 10 parts of subprostrate sophora, 10 parts of rheum officinale, 10 parts of Radix Glycyrrhizae, 10 parts of the seed of cowherb, 15 parts of rhizoma typhonii, 10 parts of camphor, 20 parts of Radix Astragali, pellet
Ginseng 10 parts, 10 parts of bombyx batryticatus, 10 parts of scorpio, 15 parts of pheretima, 15 parts of uncaria the mixed mixture of the prepared slices of Chinese crude drugs be added to 2 times of matter
It is impregnated 15 days in 95% ethyl alcohol of amount, stirring is primary daily, will bubble out liquid and pours out, and remaining Chinese medicine is put in boiler in 100 °C of rings
Steamed 2 hours under border, the supernatant in above two step is purified respectively drain the extract that liquid obtains be added 100 parts of camphor,
Ointment made of 1000 parts of vaseline.
2. a kind of method for the external-applied ointment for preparing treatment apoplexy sequelae described in claim 1, it is characterised in that: be by
The mixture of medicine medicine materical crude slice, which is added in 95% ethyl alcohol of 2 times of quality, to be impregnated 15 days, and stirring is primary daily, will be bubbled out liquid and is poured out, remaining
Chinese medicine is put in boiler to be steamed 2 hours under 100 °C of environment, and the supernatant in above two step is purified respectively and drains liquid, is obtained
To the pure powder of extract Chinese medicine；Vaseline is fallen and is boiled in pot, the pure powder of Chinese medicine is put into and mixes, it is mixed to be put into camphor when cooling to 45 °C
It is even, ointment is made.
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| CN105709194A (en) * | 2016-03-22 | 2016-06-29 | 山东明人福瑞达卫生材料有限公司 | Traditional Chinese medicine composition for treating stroke and external preparation thereof and preparation method of external preparation |
| CN105687798A (en) * | 2016-03-22 | 2016-06-22 | 山东明人福瑞达卫生材料有限公司 | External traditional Chinese medicinal preparation for treating stroke and preparation method of external traditional Chinese medicinal preparation |
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| CN1393235A (en) * | 2001-06-26 | 2003-01-29 | 利津县第二人民医院 | Plaster for treating facial neuritis and its preparing process |
| CN1951493A (en) * | 2006-11-15 | 2007-04-25 | 王信锁 | Chinese medicinal preparation for treating apoplexy sequelae |
| CN102579720A (en) * | 2012-02-28 | 2012-07-18 | 卢卫平 | Medicament for treating facial paralysis and preparation method thereof |
| CN103893441A (en) * | 2014-04-01 | 2014-07-02 | 徐跃萍 | Qianzheng plaster for treating hemiplegia |
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2015
- 2015-05-19 CN CN201510255116.4A patent/CN104784398B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1393235A (en) * | 2001-06-26 | 2003-01-29 | 利津县第二人民医院 | Plaster for treating facial neuritis and its preparing process |
| CN1951493A (en) * | 2006-11-15 | 2007-04-25 | 王信锁 | Chinese medicinal preparation for treating apoplexy sequelae |
| CN102579720A (en) * | 2012-02-28 | 2012-07-18 | 卢卫平 | Medicament for treating facial paralysis and preparation method thereof |
| CN103893441A (en) * | 2014-04-01 | 2014-07-02 | 徐跃萍 | Qianzheng plaster for treating hemiplegia |
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| Title |
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