CN102114149B - Chinese medicine preparation for treating epilepsy - Google Patents

Chinese medicine preparation for treating epilepsy Download PDF

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Publication number
CN102114149B
CN102114149B CN2011100419331A CN201110041933A CN102114149B CN 102114149 B CN102114149 B CN 102114149B CN 2011100419331 A CN2011100419331 A CN 2011100419331A CN 201110041933 A CN201110041933 A CN 201110041933A CN 102114149 B CN102114149 B CN 102114149B
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China
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parts
chinese medicine
medicine preparation
treatment
rhizoma
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CN2011100419331A
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CN102114149A (en
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于晓瑾
杨连荣
张哲锋
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HEILONGJIANG KANGYUAN NERVE SPECIALIZED HOSPITAL CO Ltd
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HEILONGJIANG KANGYUAN NERVE SPECIALIZED HOSPITAL CO Ltd
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Abstract

The invention relates to a Chinese medicine preparation for treating epilepsy, which has good treatment effect and little side effect. The Chinese medicine preparation is prepared from the following raw materials in parts by weight of 10-50 parts of bupleurum, 10-50 parts of scutellaria baicalensis, 10-50 parts of pinellia tuber, 10-30 parts of Chinese rhubarb, 10-40 parts of dragon bones, 10-50 parts of oyster, 10-40 parts of raw sienna, 5-20 parts of scorpion, 10-30 parts of uncaria, 5-30 parts of bombys batryticatus, 8-35 parts of Szechwan gentian, 10-35 parts of calamus through mixing and purifying into powder. The Chinese medicine preparation is verified by years of clinical experience, and is well received by patients due to obvious effect.

Description

The Chinese medicine preparation for the treatment of epileptics
(1), technical field
What the present invention relates to is a kind of traditional Chinese medicine product, specifically a kind of Chinese medicine preparation that is used for the treatment of epileptics.
(2), background technology
Epileptics is 0.5% at the sickness rate of China, and is very common clinically.Its main clinical manifestation is: breaking out falls down to the ground, loss of consciousness, and whole body is twitched, and spits out white foams, and two are upwards turned over, and each outbreak continues 1-3 minute.Epileptics is very large to people's harm, mainly contain following some: the infringement of (1) brain function: the every outbreak of epilepsy once, brain cell damages once, long-term epilepsy shows effect repeatedly, the patient can intelligence descend, at last disablement gradually, even viability.(2) fortuitous casualty:
No matter because epilepsy is that time, place, environment again can not oneself control break out and fall down to the ground, traumatic injury, scald, drowned, vehicle accident occur easily.(3) psychic trauma: because the frequent outbreak of epileptics all brings impact to patient's employment, marriage, family life, thereby epileptic's ergasia is more oppressive, physical and mental health is greatly affected, thus to epileptics should take in time, effectively way is treated.
The Therapeutic Method of epileptics has western medicine and treatment by Chinese herbs at present:
One, western medicine: the medicine for the treatment of at present epileptics is a lot, take phenytoin Sodium as representative.Its action principle mainly is epileptogenic focus discharge in the control epileptic brain, and western thing is of short duration action time, so needs of patients for a long time, regularly, is quantitatively taken one or more antiepileptics.Yet this class drug side effect is more, and the side effect such as hirsutism, pachylosis, bradykinesia, spirit are poor, liver function damage, blood leucocyte minimizing often appear that gingiva thickens, in long-term taking, so the patient often is difficult to adhere to taking medicine.And the considerable part epileptic patient is arranged, it is invalid to heal with medicine.
Two, treatment by Chinese herbs, this product is pure Chinese medicinal preparation, and long-term use and have small side effects, and drug effect is rapid, dosage is accurate, reliable effect.The batch production of this product has good market potential, the market demand.And this product is evident in efficacy in my institute's clinical practice for many years, deeply is subjected to patient's welcome.Through the relevant further investigation of the systems such as clinical pharmacology, will declare new Chinese medicine behind the condition maturity, for this sick new force that increases is treated by China.
(3), summary of the invention
The object of the invention is to provide a kind of therapeutic effect good, the Chinese medicine preparation of the insane disease for the treatment of that side effect is little.
The object of the present invention is achieved like this: it by weight portion is: Radix Bupleuri 10-50 part, Radix Scutellariae 10-50 part, Rhizoma Pinelliae 10-50 part, Radix Et Rhizoma Rhei 10-30 part, Os Draconis 10-40 part, Concha Ostreae 10-50 part, Haematitum 10-40 part, Scorpio 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Bombyx Batryticatus 5-30 part, Rhizoma Coptidis 8-35 part, Rhizoma Acori Graminei 10-35 part are made.
This prescription in clinical use for many years, and is evident in efficacy.Be only limited at present the clinical use in my institute, outside institute, sell and use.
Adopt the present invention to carry out the clinical observation test in the neural section hospital of Heilungkiang Kang Yuan, model case is described below:
Case 1, king so-and-so, man, 17 years old, people from Baiquan County, Heilongjiang Province.The patient is grand mal first, faints suddenly, and syncope, slobbering, tetany, gatism is revived after about 2~3 minutes, conscious dizziness after waking up, headache, drowsiness, lassitude and weak.Later on per month grand mal several times, every day is petit mal for several times.Hospital is diagnosed as electroencephalogram in Xuan Wu, Beijing: focus epilepsy (right side hemisphere focus).Give the Western medicine such as oral sodium valproate, fail to control.In December, 2008 comes my institute's treatment, takes 1 dose in Chinese medicine of the present invention one day, sooner or later after meal 2 sub-services.Through a treatment in month, grand mal control subtracted Western medicine 1/2 amount then, and Western medicine is removed entirely after 2 weeks.Took traditional Chinese medicine 2 months, petit mal is basic controlling also again.Through two course of therapy, conditions of patients is stable, works.Follow up a case by regular visits to so far not recurrence.
Case 2, Zhang, woman, 5 years old, people from Harbin City.Come institute medical on July 15th, 2008.Fall down to the ground during outbreak, tic of the limbs, the eyes turning upwards, spit out white foams, go into a coma and do not know, show effect less than one minute, red tongue is yellow greasy, rolling pulse.Be diagnosed as essential epilepsy.Accept the treatment by Chinese herbs of the present invention of my institute since on August 18th, 2008, came institute's check on November 8th, 2008, transference cure, it is normal to look into electroencephalogram, stable disease, all are normal, follow up a case by regular visits to so far and do not send out.
Case 3, Zhao so-and-so, 23 years old people from Mudanjiang City of man.Morbidity in the time of 12 years old is not known people, tic of the limbs, is spat out white foams during outbreak, gnathospasma, the eyes turning upwards, should of exhaling dusk.Take phenobarbital, phenytoin Sodium, symptom are not effectively controlled, and be to our hospital on March 6th, 2008.Have a medical check-up when examining: god is clear, language is sharp, look into the heart, lung, liver, spleen no abnormality seen, extremity activity freely, the neurologic check no abnormality seen, and tongue is talked, tongue is bored with stringy,thready and rapid pulse in vain; EEG (electrocardiogram) examination result is extensive abnormal electroencephalogram.It is controlled to take month state of an illness of Chinese medicine of the present invention, on June 1st, 2008 check, and electroencephalogram is normal, and the state of an illness is steady, the outbreak of following up a case by regular visits to that so far there are no.
Case 4, Lee so-and-so, 26 years old Acheng City people of Heilongjiang Province of man, numb because of the paroxysmal left limb, twitch to more than in 7 years and go to a doctor in January, 2009.Patient's dim complexion, dull expression, left limb is dumb, and self-induction is numb, insomnia, cardiopalmus.Be diagnosed as localized epilepsy.After taking treatment by Chinese herbs of the present invention, it is controlled to show effect after 1 month, and look flexible, and complexion turns China, the amelioration of sleeping night, and cardiopalmus disappears, and it is few that the body of the tongue speckle turns, and follows up a case by regular visits to after 1 year, the sick recovery from illness, not more not repeatedly.
Case 5, bent so-and-so, 38 years old Shuangcheng City people of Heilongjiang Province of man.Calendar year 2001 sudden onset, because unconsciousness appears in interruption, get around, to murmur to oneself is rubbed hands and is made clicks, rattiness at ordinary times, treatment is not everywhere got better and is turned, come my institute in February, 2009, is diagnosed as psychomotor seizure.After taking treatment by Chinese herbs of the present invention, sb.'s illness took a favorable turn behind the two weeks, has no Relapse rate in half a year, follows up a case by regular visits to in January, 2011, recurrence that so far there are no.
Case 6, party so-and-so, women, 34 years old Yichun peasant of Heilongjiang Province.The nineteen ninety-five outbreak is interrupted and twitched 9 years.Conscious abdominal part pain has intestinal gas to rise and feels that then give a cry several seconds before the outbreak, sudden loss of consciousness is fallen over, the tetanic contraction of whole-body muscle, head is to layback, mouthful Hu Kaihou is closed, lisps, and spits out white foams, turns on the eyes, whole-body muscle clonic spasm, the upper limb flexing, two hold act, and two lower limb stretch tetanic.About 3 minutes clear-headed, and pupil is normal by large change, lethargy, memoryless incidence after waking up.Take treatment by Chinese herbs of the present invention in May, 2009 behind my institute's expert diagnosis, follow up a case by regular visits to have no outbreak in 2 years.
Case 7, all so-and-so, male, 38 years old, the Suihua City peasant of Heilongjiang Province.Met traffic accident in 1988, and did operation of opening cranium, postoperative causes the epileptics grand mal, over 20 years, be national various big hospital treatment, not getting better turns, all be that during the medication, the state of an illness is alleviated to some extent with some Western medicine and treatment by Chinese herbs, dose one subtracts aggravation, and dosage progressively strengthens, because patient's administration time is oversize, medicine has been produced drug resistance and paid effect, and caused a series of complication, it is unstable to walk, babble.In October, 2009, come my institute to take treatment by Chinese herbs of the present invention, the state of an illness takes a turn for the better gradually after 2 months, and now, the existing time more than 2 years did not show effect.。
Case 8, seal so-and-so, man, 37 years old, the Yilan County workman of Heilongjiang Province.9 years medical histories show as loss of consciousness during outbreak, turn on two, spit out white foams, extremity are twitched, and once go the ground treatments such as Beijing, Tianjin, it is not obvious to take sodium valproate, appropriate Thailand, carbamazepine therapeutic effect, shows effect 5-6 time per month, and large hospital is diagnosed as intractable epilepsy in Beijing.Its household recognizes that on the net there is the new method of this treatment epilepsy in my institute, and in May, 2010, my institute received treatment, and after taking treatment by Chinese herbs of the present invention, showing effect after two months has stopped, and takes medicine and follows up a case by regular visits to so far not outbreak.
(4), the specific embodiment
The below is for a more detailed description to the present invention: according to weight portion be: the ratio of Radix Bupleuri 10-50 part, Radix Scutellariae 10-50 part, Rhizoma Pinelliae 10-50 part, Radix Et Rhizoma Rhei 10-30 part, Os Draconis 10-40 part, Concha Ostreae 10-50 part, Haematitum 10-40 part, Scorpio 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Bombyx Batryticatus 5-30 part, Rhizoma Coptidis 8-35 part, Rhizoma Acori Graminei 10-35 part is made each raw material mixing pulverize.

Claims (1)

1. Chinese medicine preparation for the treatment of epileptics, it is characterized in that: the ratio of Radix Bupleuri 10-50 part, Radix Scutellariae 10-50 part, Rhizoma Pinelliae 10-50 part, Radix Et Rhizoma Rhei 10-30 part, Os Draconis 10-40 part, Concha Ostreae 10-50 part, Haematitum 10-40 part, Scorpio 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Bombyx Batryticatus 5-30 part, Rhizoma Coptidis 8-35 part, Rhizoma Acori Graminei 10-35 part by weight, each raw material mixing pulverize is made.
CN2011100419331A 2011-02-15 2011-02-15 Chinese medicine preparation for treating epilepsy Expired - Fee Related CN102114149B (en)

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105963453A (en) * 2016-06-27 2016-09-28 三穗县长吉乡赤瓦村卫生室 Chinese patent medicine for curing epilepsy
CN113288958B (en) * 2021-05-19 2022-08-19 成都中医药大学附属医院 Pharmaceutical composition for treating epilepsy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1621055A (en) * 2003-11-27 2005-06-01 潘志安 Pure Chinese traditional medicine for treating epilepsia
CN101905005A (en) * 2009-06-04 2010-12-08 赵怀谦 Formula of traditional Chinese medicine for treating epilepsy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1621055A (en) * 2003-11-27 2005-06-01 潘志安 Pure Chinese traditional medicine for treating epilepsia
CN101905005A (en) * 2009-06-04 2010-12-08 赵怀谦 Formula of traditional Chinese medicine for treating epilepsy

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
单纯中药治疗癫痫病的研究进展;朱欧鸰等;《世界中西医结合杂志》;20100331;第5卷(第3期);272-275 *
吴素芹.癫痫各类代表方与常用药物探析.《社区医学杂志》.2008,第6卷(第14期),51-53.
朱欧鸰等.单纯中药治疗癫痫病的研究进展.《世界中西医结合杂志》.2010,第5卷(第3期),272-275.
癫痫各类代表方与常用药物探析;吴素芹;《社区医学杂志》;20080731;第6卷(第14期);51-53 *

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Inventor after: Yu Xiaojin

Inventor after: Yang Lianrong

Inventor after: Zhang Zhefeng

Inventor before: Yu Xiaojin

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Free format text: CORRECT: INVENTOR; FROM: YU XIAOJIN TO: YU XIAOJIN YANG LIANRONG ZHANG ZHEFENG

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