CN104784324A - Preparation method for traditional Chinese medicine suppository for treating cervical erosion - Google Patents
Preparation method for traditional Chinese medicine suppository for treating cervical erosion Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine suppository for treating cervical erosion. The traditional Chinese medicine suppository is prepared from the following main raw materials in parts by weight: 4 parts of herba portulacae, 5 parts of flavescent sophora root, 13 parts of cordate houttuynia, 4 parts of cluster mallow fruit, 6 parts of lithospermum erythrorhizon, 3 parts of leonurus japonicus fruit, 0.8 part of red halloysite, 13 parts of herba plantaginis and 40 parts of sesame oil. The traditional Chinese medicine suppository disclosed by the invention is prepared based on the principle of cognition and treatment for pathogenesis of cervical erosion in traditional Chinese medicine and on the basis of referring to modern medical research achievements, and has the effects of arresting discharge and relieving itching, clearing away heat and toxic materials and clearing heat and drying dampness, thereby achieving the aim of completely healing cervical erosion.
Description
this case is divisional application, original bill application number 201410204111.4, applying date 2014.5.15, a kind of Chinese medicine suppository for the treatment of cervical erosion of title and preparation method thereof.
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine suppository for the treatment of cervical erosion and preparation method thereof.
Background technology
Cervical erosion is one of common gynaecopathia, and sickness rate is about 1/3rd of Women of childbearing age, and its sickness rate is in ascendant trend year by year, the serious health that have impact on women.
Cervical erosion is modal local feature in chronic metritis pathological process, owing to flooding by rheuminess thing, cervical squamous intraepithelial comes off, covered by the columnar epithelium of cervical canal and replace, namely cervical erosion is shown as, clinically by the size of cervical erosion area, cervical erosion is divided into gently, in, weigh three kinds of degree, cardinal symptom has: 1. leucorrhoea grow in quantity: leucorrhoea grow in quantity is the cardinal symptom of primary disease, usual leucorrhea be creamy white or flaxen purulent secretion Nai She Stone-bridge Ren door weary, sometimes for courageous and upright or be mingled with the blood streak.2. itching of vulva pain: vulvovaginal due to leucorrhoea grow in quantity stimulates can secondary vulvitis or vaginitis and cause vulvovaginal pruritus pain.3. lower abdomen and waist and sacrum pain: can along utero-sacral ligament when inflammation is heavier, cardinal ligament spreads and causes inflammation of pelvic connective tissue Nai She Stone-bridge Ren door weary, causes hypogastric region or waist and sacrum pain, and with bearing down.4. frequent micturition or dysuria: when inflammation involves trigone of urinary bladder or perivesical, frequent micturition or dysuria can be occurred.5. infertile: the leucorrhea of thickness is unfavorable for Sperm penetration, therefore serious cervicitis can cause infertile.
The health of cervical erosion to women has a great impact, especially moderate, severe rotten to the corn time, the secretions meeting showed increased of cervix uteri, quality thickness, and have a large amount of leukocyte, this can have a negative impact to the mobility of sperm, sperm is hindered to enter uterine cavity, impact is become pregnant, and cervical erosion can lead to complications, and can cause the inflammation of other organs.Medically Drug therapy, operative treatment and laser therapy three kinds are mainly contained for the treatment of cervical erosion at present.Drug therapy is applicable to the patient that rotten to the corn face is little, inflammatory infiltration is more shallow or limit by condition, and drug administration can produce stimulation to stomach, causes some side reactions, and curative effect is not remarkable; Operative treatment may cause wound area larger, scar, even may return and affect the normal physiological function of patient; Ar-Laser Treatment for Cervicitis can at the cervix uteri scar of patient, and cervix uteri is become does not have elasticity, and the fertility later to patient can affect.
Chinese medicine has certain advantage in treatment cervical erosion, and suppository and suppository are one of ancient dosage form, China is with a long history with suppository in treatment disease, and suppository can be avoided medicine to the zest of gastric mucosa, can play lubrication, antibacterial, parasite killing, convergence, pain relieving, the local action such as antipruritic at tract, can more effective treatment cervical erosion.
Application publication number is CN 103432361A(application number 201310387736.4) Chinese patent literature disclose a kind of by name " a kind of Chinese medicinal film for the treatment of cervical erosion ", this Chinese medicinal film is made up of Indigo Naturalis 25-35g, Sanguis Draxonis 25-35g, Cortex Phellodendri 15-25g, Rhizoma Coptidis 10-20g, Fructus Cnidii 25-35g, Matrii Sulfas Exsiccatus 8-12g, Herba Verbenae 25-35g, Borneolum Syntheticum 10-20g, Camphora 5-15g.Application publication number is CN 102846676A(application number 201210361372.8) Chinese patent literature disclose a kind of by name " a kind of Chinese medicine for the treatment of cervical erosion ", its by Pollen Pini 5-10 gram, Nidus Vespae 1-3 gram, Borneolum Syntheticum 0.2-0.8 gram form.Application publication number is CN 102824544A(application number 201210357586.8) Chinese patent literature disclose a kind of by name " a kind of Chinese medicine for the treatment of cervical erosion ", it is by Effect of Chinese Medicine Qing washing liquid and Chinese and Western medicated powder Synergistic treatment, Effect of Chinese Medicine Qing washing liquid is made up of Cortex Lycii, Rhizoma Paridis, Herba Penthori chinensis, Herba Violae, Caulis Lonicerae, Herba lespedezae floribundae, Flos Chrysanthemi Indici, Rubus delavayi Franch., Radix Clematidis, Cortex Hibisci, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli, Os Sepiae, Pericarpium Granati, Radix Et Rhizoma Rhei, Herba Andrographis, and medicated powder is Pseudobulbus Bletillae (Rhizoma Bletillae), Sanguis Draxonis, oxytetracycline and metronidazole powder respectively.
In a word, Chinese medicine achieves certain curative effect in treatment cervical erosion, but also there are some problems, and some curative effect of medication is not remarkable, and can cause certain side effect to patient, therefore needs perfect further.
Summary of the invention
For the present situation that prior art is slightly not enough, the object of this invention is to provide a kind of Chinese medicine suppository for the treatment of cervical erosion and preparation method thereof, Chinese medicine suppository of the present invention is to the pathogenetic understanding of cervical erosion and Therapeutic Principle based on Chinese medicine, basis with reference to modern medical service Research Achievement is made, there is effect of astringent or styptic treatment for spontaneous sweating antipruritic, heat-clearing and toxic substances removing, heat clearing and damp drying, thus reach the object of curing cervical erosion completely.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The Chinese medicine suppository for the treatment of cervical erosion, takes off the primary raw material stating weight proportion and is prepared from: Herba Portulacae 3-6 part, Radix Sophorae Flavescentis 4-9 part, Herba Houttuyniae 10-20 part, Fructus Malvae 3-9 part, Radix Arnebiae (Radix Lithospermi) 5-9 part, Fructus Leonuri 2-6.5 part, Halloysitum Rubrum 0.5-1.5 part, Herba Plantaginis 9-20 part, Oleum Sesami 30-60 part.
The Chinese medicine suppository for the treatment of cervical erosion, preferred scheme is, take off the primary raw material stating weight proportion to be prepared from: Herba Portulacae 4-5 part, Radix Sophorae Flavescentis 5-7 part, Herba Houttuyniae 13-17 part, Fructus Malvae 4-8 part, Radix Arnebiae (Radix Lithospermi) 6-8 part, Fructus Leonuri 3-5 part, Halloysitum Rubrum 0.8-1.2 part, Herba Plantaginis 13-17 part, Oleum Sesami 40-50 part.
The Chinese medicine suppository for the treatment of cervical erosion, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Herba Portulacae 4.5 parts, Radix Sophorae Flavescentis 6 parts, Herba Houttuyniae 15 parts, Fructus Malvae 6 parts, Radix Arnebiae (Radix Lithospermi) 7 parts, Fructus Leonuri 4 parts, Halloysitum Rubrum 1 part, Herba Plantaginis 15 parts, 45 parts, Oleum Sesami.
The preparation method of the Chinese medicine suppository of above-mentioned treatment cervical erosion, preparation process is as follows:
(1) be soaked in water Herba Portulacae, Radix Sophorae Flavescentis, Fructus Malvae, Fructus Leonuri 18-30 hour, and add Herba Plantaginis intense fire and boil, fire of larding speech with literary allusions is decocted slowly, decocts to finger immersion and have bonding sense to be advisable, medical filtration, dry in the air to about 50 DEG C for subsequent use;
(2) Radix Arnebiae (Radix Lithospermi) pulverize is crossed 95-135 mesh sieve, powder is poured in Oleum Sesami and is stirred, and leaves standstill 1.5-4.5 hour;
(3) Herba Houttuyniae adds water 250-450 milliliter, and intense fire boils, and turn 10-18 minute at a simmer, medical filtration is for subsequent use;
(4) Halloysitum Rubrum pulverize is crossed 115-165 mesh sieve, gained powder is for subsequent use;
(5) by gains mixing in step (1)-(4), after stirring, be processed into according to the preparation method of suppository the suppository that weight is 4.5g.
The preparation method of the Chinese medicine suppository of above-mentioned treatment cervical erosion, preferred scheme is, step (1) is soaked in water 22-26 hour (preferably 24 hours).
The preparation method of the Chinese medicine suppository of above-mentioned treatment cervical erosion, preferred scheme is, step (2) crosses 105-125 mesh sieve (preferably 115 mesh sieves).
The preparation method of the Chinese medicine suppository of above-mentioned treatment cervical erosion, preferred scheme is, step (2) leaves standstill 2.5-3.5 hour (preferably 3 hours).
The preparation method of the Chinese medicine suppository of above-mentioned treatment cervical erosion, preferred scheme is, step (3) Herba Houttuyniae adds water 300-400 milliliter (preferably 350 milliliters).
The preparation method of the Chinese medicine suppository of above-mentioned treatment cervical erosion, preferred scheme is, step (3) turns 12-16 at a simmer minute (preferably 14 minutes).
The preparation method of the Chinese medicine suppository of above-mentioned treatment cervical erosion, preferred scheme is, step (4) crosses 135-155 mesh sieve (preferably 145 mesh sieves).
Best using method: be the curative effect making the present invention reach best, Chinese medicine suppository every day for the treatment of cervicitis 1 time, each 1,7 days courses for the treatment of.
The pharmacological effect of each raw material is respectively:
Herba Portulacae: be the dry aerial parts of portulacaceous plant Herba Portulacae.Nature and flavor: sour in the mouth, cold.Gui Jing: return liver, large intestine channel.Effect: heat-clearing and toxic substances removing, cooling blood for hemostasis.Cure mainly: for toxic-heat and blood stasis, carbuncle furunculosis, eczema, erysipelas, snake bite and insect sting, has blood in stool, hemorrhoidal bleeding, metrostaxis.
Radix Sophorae Flavescentis: nature and flavor: bitter in the mouth, cold in nature.Gui Jing: GUIXIN, liver, stomach, large intestine, urinary bladder channel.Effect: heat clearing and damp drying, parasite killing, diuresis.Cure mainly: hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Herba Houttuyniae: nature and flavor: acrid in the mouth, cold nature.Gui Jing: return lung meridian.Effect: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.Cure mainly: lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Fructus Malvae: nature and flavor: sweet in the mouth, puckery, cool in nature.Effect: clearing away heat and promoting diuresis, detumescence.Cure mainly: urine retention, edema, thirsty; Urinary tract infection.
Radix Arnebiae (Radix Lithospermi): nature and flavor: sweet in the mouth, salty, cold in nature.Gui Jing: GUIXIN, Liver Channel.Effect: removing heat from blood, invigorates blood circulation, removing toxic substances rash.Cure mainly: heat in blood poison is contained, and class's rash purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.
Fructus Leonuri: be the fruit of Labiatae mother wort plant Herba Leonuri and Herba Leonuri Sibirici.Composition: leonuri,fructus contains allene class fatty acid containing alkaloid, herb containing phenolic glycoside class, Herba Leonuri Sibirici fruit kind oil.Pharmacology: have hypotensive effect, has the effect of stimulon palace excitement.The property of medicine: sweet, pungent, be slightly cold, mild toxicity, return Liver Channel.
Function cures mainly: blood circulation promoting and blood stasis dispelling, liver heat removing and eyesight improving.
Halloysitum Rubrum: have another name called red symbol, red Gao Ling, HALLOYSITUM RUBRUM is finely divided many mineral aggregates that silicates halloysite race Ore halloysite forms jointly with oxide-based bloodstone or hydrogeneous oxide-based limonite.The property of medicine: this product is block aggregation, in light red, red to aubergine, or red and white in textured, body is comparatively light, and matter is soft, and water absorbing capacity is strong, and micro-have clay gas, sweet in the mouth, puckery, and property is put down.Composition: main component is aluminium silicate hydrate, also containing trace element such as titanium, nickel, strontium, barium.Find according to modern pharmacological research, this medical instrument has effect of relieving diarrhea with astringent, hemostasis, removing dampness sore, for chronic diarrhea chronic dysentery, has blood in stool, and skin ulcer wound is burst for a long time and do not held back, eczema etc.
Herba Plantaginis: nature and flavor: sweet in the mouth, cold in nature.Gui Jing: return liver, kidney, lung, small intestine meridian.Effect: clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.Cure mainly: edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Oleum Sesami: Chinese medicine thinks this product sweet in the mouth, cool in nature, has effect of loosening bowel to relieve constipation, removing toxic substances and promoting granulation.Record according in Compendium of Material Medica: " have moisturize, detoxify, pain relieving, detumescence merit "." not Lu " be said: " sharp large intestine, afterbirth does not fall.Survivor's lump of rubbing swells, raw alopecia ".Purposes: lubricant and excipient.For oral administration can intestine moistening, lung moistening; Be used as ointment machin plaster substrate outward.
Chinese medicine suppository of the present invention has effect of heat clearing and damp drying, astringent or styptic treatment for spontaneous sweating antipruritic, antiinflammatory parasite killing, and completely by theory of Chinese medical science formula, its pathogen is dispelled, and recovers healthy energy, thus reaches good therapeutic effect.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the Chinese medicine suppository for the treatment of cervical erosion, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Portulacae 3 parts, Radix Sophorae Flavescentis 4 parts, Herba Houttuyniae 10 parts, Fructus Malvae 3 parts, Radix Arnebiae (Radix Lithospermi) 5 parts, Fructus Leonuri 2 parts, Halloysitum Rubrum 0.5 part, Herba Plantaginis 9 parts, 30 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine suppository, preparation process is as follows:
(1) Herba Portulacae, Radix Sophorae Flavescentis, Fructus Malvae, Fructus Leonuri are soaked in water 18 hours, add Herba Plantaginis intense fire and boil, fire of larding speech with literary allusions is decocted slowly, decoct to finger immersion have bonding sense be advisable, medical filtration, dry in the air to about 50 DEG C for subsequent use;
(2) Radix Arnebiae (Radix Lithospermi) pulverize is crossed 95 mesh sieves, powder is poured in Oleum Sesami and is stirred, and leaves standstill 1.5 hours;
(3) Herba Houttuyniae adds water 250 milliliters, and intense fire boils, and turn 10 minutes at a simmer, medical filtration is for subsequent use;
(4) Halloysitum Rubrum pulverize is crossed 115 mesh sieves, gained powder is for subsequent use;
(5) by gains mixing in step (1)-(4), after stirring, be processed into according to the preparation method of suppository the suppository that weight is 4.5g.
typical case onefinish XX, female, 28 years old.Patient's readme finds oneself leucorrhoea grow in quantity recently, and leucorrhea starts jaundice, and checking severely through doctor is cervical erosion, had certain improvement after active treatment, but be soon reoccurred again, during chemical examination, leucorrhea also has inflammation, the abnormal pruritus of pudendum, takes some Western medicine without positive effect afterwards.Use the present embodiment gained Chinese medicine suppository, adopt every day 1 time, each 1,7 days courses for the treatment of.Use 2 days, patient leucorrhea reduces; Use 5 days, patient's pruritus vulvae symptom disappears, and malaise symptoms is alleviated all to some extent; Continue use 2 days, patient's self-induction is fully recovered.
embodiment 2the Chinese medicine suppository for the treatment of cervical erosion, takes off the primary raw material stating weight proportion and is prepared from (getting 20g for every part): Herba Portulacae 6 parts, Radix Sophorae Flavescentis 9 parts, Herba Houttuyniae 20 parts, Fructus Malvae 9 parts, Radix Arnebiae (Radix Lithospermi) 9 parts, Fructus Leonuri 6.5 parts, Halloysitum Rubrum 1.5 parts, Herba Plantaginis 20 parts, 60 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine suppository, preparation process is as follows:
(1) Herba Portulacae, Radix Sophorae Flavescentis, Fructus Malvae, Fructus Leonuri are soaked in water 30 hours, add Herba Plantaginis intense fire and boil, fire of larding speech with literary allusions is decocted slowly, decoct to finger immersion have bonding sense be advisable, medical filtration, dry in the air to about 50 DEG C for subsequent use;
(2) Radix Arnebiae (Radix Lithospermi) pulverize is crossed 135 mesh sieves, powder is poured in Oleum Sesami and is stirred, and leaves standstill 4.5 hours;
(3) Herba Houttuyniae adds water 450 milliliters, and intense fire boils, and turn 18 minutes at a simmer, medical filtration is for subsequent use;
(4) Halloysitum Rubrum pulverize is crossed 165 mesh sieves, gained powder is for subsequent use;
(5) by gains mixing in step (1)-(4), after stirring, be processed into according to the preparation method of suppository the suppository that weight is 4.5g.
typical case twoliu XX, female, 29 years old.Cervical erosion is suffered from patient's readme 1 year, several years ago patient is busy with work always, do not consider the thing of raw baby, the raw baby of plan afterwards, be not pregnant, and oneself yet regular malaise symptoms such as appearance pruritus vulvae, leucorrhea abnormal always, go examination in hospital be cervical erosion cause be not easy pregnancy, drug administration is treated, but cervical erosion having no is clearly better.Use the present embodiment gained Chinese medicine suppository, adopt every day 1 time, each 1,7 days courses for the treatment of.Use 4 days, patient leucorrhea reduces, and malaise symptoms alleviates, and uses 7 days, the transference cures such as patient's pruritus vulvae, leucorrhea abnormal; Continue use 3 days, the cervical erosion of patient is cured completely, and between the operating period, patient produces without any discomfort.
embodiment 3the Chinese medicine suppository for the treatment of cervical erosion, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Herba Portulacae 4 parts, Radix Sophorae Flavescentis 5 parts, Herba Houttuyniae 13 parts, Fructus Malvae 4 parts, Radix Arnebiae (Radix Lithospermi) 6 parts, Fructus Leonuri 3 parts, Halloysitum Rubrum 0.8 part, Herba Plantaginis 13 parts, 40 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine suppository, preparation process is as follows:
(1) Herba Portulacae, Radix Sophorae Flavescentis, Fructus Malvae, Fructus Leonuri are soaked in water 22 hours, add Herba Plantaginis intense fire and boil, fire of larding speech with literary allusions is decocted slowly, decoct to finger immersion have bonding sense be advisable, medical filtration, dry in the air to about 50 DEG C for subsequent use;
(2) Radix Arnebiae (Radix Lithospermi) pulverize is crossed 105 mesh sieves, powder is poured in Oleum Sesami and is stirred, and leaves standstill 2.5 hours;
(3) Herba Houttuyniae adds water 300 milliliters, and intense fire boils, and turn 12 minutes at a simmer, medical filtration is for subsequent use;
(4) Halloysitum Rubrum pulverize is crossed 135 mesh sieves, gained powder is for subsequent use;
(5) by gains mixing in step (1)-(4), after stirring, be processed into according to the preparation method of suppository the suppository that weight is 4.5g.
embodiment 4the Chinese medicine suppository for the treatment of cervical erosion, takes off the primary raw material stating weight proportion and is prepared from (getting 40g for every part): Herba Portulacae 5 parts, Radix Sophorae Flavescentis 7 parts, Herba Houttuyniae 17 parts, Fructus Malvae 8 parts, Radix Arnebiae (Radix Lithospermi) 8 parts, Fructus Leonuri 5 parts, Halloysitum Rubrum 1.2 parts, Herba Plantaginis 17 parts, 50 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine suppository, preparation process is as follows:
(1) Herba Portulacae, Radix Sophorae Flavescentis, Fructus Malvae, Fructus Leonuri are soaked in water 26 hours, add Herba Plantaginis intense fire and boil, fire of larding speech with literary allusions is decocted slowly, decoct to finger immersion have bonding sense be advisable, medical filtration, dry in the air to about 50 DEG C for subsequent use;
(2) Radix Arnebiae (Radix Lithospermi) pulverize is crossed 125 mesh sieves, powder is poured in Oleum Sesami and is stirred, and leaves standstill 3.5 hours;
(3) Herba Houttuyniae adds water 400 milliliters, and intense fire boils, and turn 16 minutes at a simmer, medical filtration is for subsequent use;
(4) Halloysitum Rubrum pulverize is crossed 155 mesh sieves, gained powder is for subsequent use;
(5) by gains mixing in step (1)-(4), after stirring, be processed into according to the preparation method of suppository the suppository that weight is 4.5g.
typical case threezhao XX, female, 25 years old.Be abortion because colporrhagia is more than after patient's pregnancy, but just occurred that leucorrhea abnormal increases, have abnormal flavour afterwards, once in a while with the blood streak, and pruritus vulvae is hard to bear, is diagnosed as cervical erosion on inspection.Use the present embodiment gained Chinese medicine suppository, adopt every day 1 time, each 1,7 days courses for the treatment of.Use 4 days, patient's malaise symptoms alleviates, and leucorrhea reduces; Use 7 days, patient's pruritus vulvae symptom disappears, and leucorrhea obviously adds minimizing; Continue use 5 days, patient's malaise symptoms disappears completely, and self-induction is fully recovered.
embodiment 5the Chinese medicine suppository for the treatment of cervical erosion, takes off the primary raw material stating weight proportion and is prepared from (getting 50g for every part): Herba Portulacae 4.5 parts, Radix Sophorae Flavescentis 6 parts, Herba Houttuyniae 15 parts, Fructus Malvae 6 parts, Radix Arnebiae (Radix Lithospermi) 7 parts, Fructus Leonuri 4 parts, Halloysitum Rubrum 1 part, Herba Plantaginis 15 parts, 45 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicine suppository, preparation process is as follows:
(1) Herba Portulacae, Radix Sophorae Flavescentis, Fructus Malvae, Fructus Leonuri are soaked in water 24 hours, add Herba Plantaginis intense fire and boil, fire of larding speech with literary allusions is decocted slowly, decoct to finger immersion have bonding sense be advisable, medical filtration, dry in the air to about 50 DEG C for subsequent use;
(2) Radix Arnebiae (Radix Lithospermi) pulverize is crossed 115 mesh sieves, powder is poured in Oleum Sesami and is stirred, and leaves standstill 3 hours;
(3) Herba Houttuyniae adds water 350 milliliters, and intense fire boils, and turn 14 minutes at a simmer, medical filtration is for subsequent use;
(4) Halloysitum Rubrum pulverize is crossed 145 mesh sieves, gained powder is for subsequent use;
(5) by gains mixing in step (1)-(4), after stirring, be processed into according to the preparation method of suppository the suppository that weight is 4.5g.
experimental example 1the clinical practice of the Chinese medicine suppository of embodiment 5 gained treatment cervical erosion: in March ,-2012 in February, 2009,180 routine patients are screened in 6 hospitals, 32.4 years old mean age, before experiment 2 weeks, Continuous Observation is carried out to this crowd, record symptom and change thereof, be divided into two groups at random, experimental group and matched group, experimental group uses embodiment 5 products obtained therefrom, and matched group uses conventional gynecological lotion.Using method is: every day 1 time, each 1,7 days courses for the treatment of.Curative effect situation criterion: cure: use a course for the treatment of of this product, pruritus vulvae is alleviated, and malaise symptoms disappears completely; Effective: use a course for the treatment of of this product, malaise symptoms alleviates or partial disappearance; Invalid: use a course for the treatment of of this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: embodiment 5 products obtained therefrom compliance test result
| Experimental group | Matched group | |
| Number of cases | 100 | 80 |
| Clinical cure number of cases | 74 | 22 |
| Effective number of cases | 23 | 34 |
| Invalid number of cases | 3 | 24 |
| Total effective rate | 97% | 70% |
Therapeutic effect: cure 74 examples (74%), effective 23 examples (23%), invalid 3 examples (3%), total effective rate 97%.Successful is better than matched group.
Between the operating period, self-induction symptom variation is as shown in table 2:
Table 2:
As shown in Table 2, use 4 days, the patients symptomatic of more than 56% improves, and pruritus vulvae alleviates, and leucorrhea reduces; Use 6 days, the patient leucorrhea of more than 75% reduces, and abnormal flavour, the blood streak disappear; Use 8 days, patient's pruritus vulvae of more than 96% alleviates, and leucorrhea reduces, and malaise symptoms improves, and some patients self-induction is fully recovered.Use 8 days in experimental group, effective percentage can reach 96%, and matched group is only 76%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (8)
1. treat a Chinese medicine suppository for cervical erosion, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Herba Portulacae 4 parts, Radix Sophorae Flavescentis 5 parts, Herba Houttuyniae 13 parts, Fructus Malvae 4 parts, Radix Arnebiae (Radix Lithospermi) 6 parts, Fructus Leonuri 3 parts, Halloysitum Rubrum 0.8 part, Herba Plantaginis 13 parts, 40 parts, Oleum Sesami.
2. the preparation method of Chinese medicine suppository according to claim 1, is characterized in that, step is as follows:
(1) be soaked in water Herba Portulacae, Radix Sophorae Flavescentis, Fructus Malvae, Fructus Leonuri 18-30 hour, and add Herba Plantaginis intense fire and boil, fire of larding speech with literary allusions is decocted slowly, decocts to finger immersion and have bonding sense to be advisable, medical filtration, dry in the air to about 50 DEG C for subsequent use;
(2) Radix Arnebiae (Radix Lithospermi) pulverize is crossed 95-135 mesh sieve, powder is poured in Oleum Sesami and is stirred, and leaves standstill 1.5-4.5 hour;
(3) Herba Houttuyniae adds water 250-450 milliliter, and intense fire boils, and turn 10-18 minute at a simmer, medical filtration is for subsequent use;
(4) Halloysitum Rubrum pulverize is crossed 115-165 mesh sieve, gained powder is for subsequent use;
(5) by gains mixing in step (1)-(4), after stirring, be processed into according to the preparation method of suppository the suppository that weight is 4.5g.
3. the preparation method of Chinese medicine suppository according to claim 2, is characterized in that, step (1) is soaked in water 22-26 hour (preferably 24 hours).
4. the preparation method of Chinese medicine suppository according to claim 2, is characterized in that, step (2) crosses 105-125 mesh sieve (preferably 115 mesh sieves).
5. the preparation method of Chinese medicine suppository according to claim 2, is characterized in that, step (2) leaves standstill 2.5-3.5 hour (preferably 3 hours).
6. the preparation method of Chinese medicine suppository according to claim 2, is characterized in that, step (3) Herba Houttuyniae adds water 300-400 milliliter (preferably 350 milliliters).
7. the preparation method of Chinese medicine suppository according to claim 2, is characterized in that, step (3) turns 12-16 at a simmer minute (preferably 14 minutes).
8. the preparation method of Chinese medicine suppository according to claim 2, is characterized in that, step (4) crosses 135-155 mesh sieve (preferably 145 mesh sieves).
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| CN201410204111.4A Active CN103948729B (en) | 2014-05-15 | 2014-05-15 | A kind of Chinese medicine suppository for the treatment of cervical erosion and preparation method thereof |
| CN201510222602.6A Pending CN104784325A (en) | 2014-05-15 | 2014-05-15 | Traditional Chinese medicine suppository for treating cervical erosion |
| CN201510222599.8A Pending CN104784323A (en) | 2014-05-15 | 2014-05-15 | Preparation method for traditional Chinese medicine suppository for treating cervical erosion |
| CN201510222603.0A Pending CN104784326A (en) | 2014-05-15 | 2014-05-15 | Traditional Chinese medicine suppository for treating cervical erosion |
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| CN201510222602.6A Pending CN104784325A (en) | 2014-05-15 | 2014-05-15 | Traditional Chinese medicine suppository for treating cervical erosion |
| CN201510222599.8A Pending CN104784323A (en) | 2014-05-15 | 2014-05-15 | Preparation method for traditional Chinese medicine suppository for treating cervical erosion |
| CN201510222603.0A Pending CN104784326A (en) | 2014-05-15 | 2014-05-15 | Traditional Chinese medicine suppository for treating cervical erosion |
| CN201510222600.7A Pending CN104800373A (en) | 2014-05-15 | 2014-05-15 | Chinese medicinal composition for treating cervical erosion |
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| CN1348782A (en) * | 2001-08-21 | 2002-05-15 | 曹琼 | Externally applied medicine for treating cervical erosion and its prepn |
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| CN1476885A (en) * | 2003-06-10 | 2004-02-25 | 王印雄 | Nianmoyankuiling for curing mucositis mucitis and its preparation |
| CN100427082C (en) * | 2005-08-02 | 2008-10-22 | 盛华（广州）医药科技有限公司 | Application of hydroxybenzoate acid and its analogue in the preparing process of medicine for preventing and treating virus infection |
| CN103565990A (en) * | 2012-07-29 | 2014-02-12 | 潘首德 | Method for preparing anti-cervical erosion suppository |
| CN103610880A (en) * | 2013-11-29 | 2014-03-05 | 青岛中科菲力工程技术研发有限公司 | Traditional Chinese medicine composition for treating cervical erosion |
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| CN1348782A (en) * | 2001-08-21 | 2002-05-15 | 曹琼 | Externally applied medicine for treating cervical erosion and its prepn |
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| 蔡玉华等: "《实用男女病性病临床手册》", 31 July 1996 * |
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| CN103948729B (en) | 2015-09-09 |
| CN104784326A (en) | 2015-07-22 |
| CN104784323A (en) | 2015-07-22 |
| CN104784325A (en) | 2015-07-22 |
| CN104800373A (en) | 2015-07-29 |
| CN103948729A (en) | 2014-07-30 |
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