CN104783165A - Method for preparing anti-alcohol raffinate from natural plant - Google Patents
Method for preparing anti-alcohol raffinate from natural plant Download PDFInfo
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- CN104783165A CN104783165A CN201510208943.8A CN201510208943A CN104783165A CN 104783165 A CN104783165 A CN 104783165A CN 201510208943 A CN201510208943 A CN 201510208943A CN 104783165 A CN104783165 A CN 104783165A
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Abstract
The invention discloses a method for preparing anti-alcohol raffinate from a natural plant and belongs to the technical field of biologically active substance. The method comprises the following steps: slicing the dried flos puerariae, kudzuvine root, hawthorn, ligusticum wallichii and oriental wormwood, putting into an extracting tank, adding water and stirring for 18h at the temperature of 80-100 DEG C to obtain a first extract; slicing the dried malt, schisandra chinensis, mung bean, black soya bean, red bean and ginseng, putting into the extracting tank, adding water and stirring for 18h at the temperature of 80-100 DEG C to obtain a second extract; slicing dried Rhodiola rosea and putting into the extracting tank, adding water and stirring for 18h at the temperature of 80-100 DEG C to obtain a third extract; separating and purifying the mixtures of the first extract, the second extract and the third extract, concentrating to greater than 10 brix degrees to obtain the final extract, and heating the final extract to the temperature from -60 DEG C to 40 DEG C within 36h to obtain the anti-alcohol raffinate. The raw materials are pure natural plants. The method provided by the invention is safe, effective and economical.
Description
Technical field
The invention belongs to bioactivator preparing technical field, be specifically related to a kind of method utilizing natural plants to prepare the raffinate that relieves the effect of alcohol.
Background technology
The alcohol entering human body is absorbed by gastric tube, mainly through liver metabolism.Under normal circumstances, liver carries out metabolism by certain speed.If the alcohol that in the short time, picked-up is excessive, is difficult to the alcohol decomposed rapidly in blood, causes acute or slow poisoning phenomenon.Especially acute poisoning phenomenon, changes directly related with the alcohol concentration in blood.So many scholars are probing into, how to reduce rapidly the alcohol concentration in blood, treatment alcohol acute poisoning disease.But many correlation techniques in the past, fail fundamentally to treat alcohol acute poisoning disease, namely fail to reduce rapidly the alcohol concentration in blood.
Summary of the invention
The object of this invention is to provide a kind of method utilizing natural plants to prepare the raffinate that relieves the effect of alcohol, the method utilizes natural plants to extract the rapid material reducing blood alcohol concentration of thing preparation, and treatment alcohol acute poisoning disease, promotes health.
A kind of method concrete steps utilizing natural plants to prepare the raffinate that relieves the effect of alcohol provided by the present invention are as follows:
(1) dry FI puerariae 1500 grams, the root of kudzu vine 1500 grams, hawthorn 1500 grams, Ligusticum wallichii 1000 grams and oriental wormwood 1000 grams are cut into 2 ~ 5mm section, drop into and extract tank, drop into the water of section 10 times of weights, stir 18 hours at temperature 80 ~ 100 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the first extraction thing.
(2) 500 grams dry, Fructus Hordei Germinatus, 1000 grams, the fruit of Chinese magnoliavine, 1000 grams, mung bean, 500 grams, black soya bean, 500 grams, red bean and ginseng 500 grams are cut into 2 ~ 5mm section, drop into and extract tank, drop into the water that section weighs 10 times, stir 18 hours at temperature 80 ~ 100 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the second extraction thing.
(3) dry rhodiola root 500 grams is cut into 2 ~ 5mm section, drops into and extract tank, drop into the water that section weighs 10 times, stir 18 hours at temperature 80 ~ 100 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the 3rd and extract thing.
(4) extract thing, the second extraction thing and the 3rd extraction thing to mix described first, obtain extracting thing mixture, then filter press is utilized to be separated the solid-state powder extracted in thing mixture with centrifugal separator, utilize particulate matter in ultracentrifugation seperator separation extraction thing mixture and protein, obtain and extract thing for the first time, the rotating speed of described ultracentrifugation seperator is 15000 revs/min ~ 20000 revs/min.
(5) utilize active carbon filter, be separated fat constituent, benzene phenoloid, tannic acid composition in extraction of described first time thing, obtain second time and extract thing.
(6) utilize ultra micro order filter, be separated the nonactive macromolecule in described second time extraction thing, carbohydrate, microorganism, obtain and extract thing for the third time.
(7) utilize decompression concentrator, described third time is extracted thing and is concentrated to more than 10 Brix degrees, obtain and finally extract thing.
(8) by described final extraction thing, in 36 hours, be warmed up to 40 DEG C from-60 DEG C, relieve the effect of alcohol described in obtained raffinate.
Extraction raw material of the present invention, FI puerariae, the root of kudzu vine, rhodiola root have the effect of promotion alcohol metabolism; Mung bean, ginseng have detoxication; Fructus Hordei Germinatus, hawthorn have promotion digestion; Ligusticum wallichii has analgesic activity; Oriental wormwood, the fruit of Chinese magnoliavine have the effect of promotion liver detoxification; Black soya bean, red bean have to promote that alcohol metabolism provides amino acid whose effect.Main material of the present invention is the extraction thing of pure natural plant completely, has security, validity, economy feature.So relieving the effect of alcohol in medicine and health-product market, product of the present invention will play central action, and progressively will substitute existing similar (purposes is identical and main material is different) product.
Detailed description of the invention
A kind of method concrete steps utilizing natural plants to prepare the raffinate that relieves the effect of alcohol provided by the present invention are as follows:
(1) dry FI puerariae 1500 grams, the root of kudzu vine 1500 grams, hawthorn 1500 grams, Ligusticum wallichii 1000 grams and oriental wormwood 1000 grams are cut into 2 ~ 5mm section, drop into and extract tank, drop into the water of section 10 times of weights, stir 18 hours at temperature 90 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the first extraction thing.
(2) 500 grams dry, Fructus Hordei Germinatus, 1000 grams, the fruit of Chinese magnoliavine, 1000 grams, mung bean, 500 grams, black soya bean, 500 grams, red bean and ginseng 500 grams are cut into 2 ~ 5mm section, drop into and extract tank, drop into the water that section weighs 10 times, stir 18 hours at temperature 90 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the second extraction thing.
(3) dry rhodiola root 500 grams is cut into 2 ~ 5mm section, drops into and extract tank, drop into the water that section weighs 10 times, stir 18 hours at temperature 90 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the 3rd and extract thing.
(4) extract thing, the second extraction thing and the 3rd extraction thing to mix described first, obtain extracting thing mixture, then filter press is utilized to be separated the solid-state powder extracted in thing mixture with centrifugal separator, utilize particulate matter in ultracentrifugation seperator separation extraction thing mixture and protein, obtain and extract thing for the first time, the rotating speed of described ultracentrifugation seperator is 18000 revs/min.
(5) utilize active carbon filter, be separated fat constituent, benzene phenoloid, tannic acid composition in extraction of described first time thing, obtain second time and extract thing.
(6) utilize ultra micro order filter, be separated the nonactive macromolecule in described second time extraction thing, carbohydrate, microorganism, obtain and extract thing for the third time.
(7) utilize decompression concentrator, described third time is extracted thing and is concentrated to more than 10 Brix degrees, obtain and finally extract thing.
(8) by described final extraction thing, in 36 hours, be warmed up to 40 DEG C from-60 DEG C, relieve the effect of alcohol described in obtained raffinate.
The experimental technique that relieves the effect of alcohol of the raffinate that relieves the effect of alcohol prepared by the present invention:
1. Test Materials:
relieve the effect of alcohol raffinate, dissolves in 1:1 ratio distilled water.
alcohol, dissolves in 1:1 ratio distilled water.
2. animal used as test:
kind: white mouse.
age in week: 5 week age.
quantity: 30 (control group 10, each 10 of experimental group a, b).
raise: common rearing conditions.
3. experimental technique:
all animals are tested after jejunitas 24 hours.
first oral experiment thing or distilled water:
Experimental group a: the experiment thing of oral weight ratio 2g/kg.
Experimental group b: the experiment thing of oral weight ratio 4g/kg.
Control group: oral equivalent distilled water.
1 hour afterwards, the alcohol of whole oral weight ratio 3g/kg
1,2,4,6,8 hour afterwards, adopt tail vein blood, adopt 0.5ml at every turn.
Concrete grouping situation is as following table:
| Grouping | Oral dose | Blood sampling time (hour) |
| Control group | Distilled water | 1,2,4,6,8， |
| Experimental group a | Experiment thing 2:2g/kg | 1,2,4,6,8， |
| Experimental group b | Experiment thing 2:4g/kg | 1,2,4,6,8， |
The relieve the effect of alcohol experimental result of relieving the effect of alcohol of raffinate of the present invention sees the following form:
The alcohol concentration of experimental result display, the experimental group a of oral 2g/kg reduces by the experimental group b of 75%, oral 4g/kg than control group minimizing 80% than control group.Visible, take the present invention and to relieve the effect of alcohol raffinate, to the alcohol concentration reduced in blood, there is the higher performance of more than 75%.
Claims (1)
1. utilize natural plants to prepare a method for the raffinate that relieves the effect of alcohol, it is characterized in that the method concrete steps are as follows:
(1) dry FI puerariae 1500 grams, the root of kudzu vine 1500 grams, hawthorn 1500 grams, Ligusticum wallichii 1000 grams and oriental wormwood 1000 grams are cut into 2 ~ 5mm section, drop into and extract tank, drop into the water of section 10 times of weights, stir 18 hours at temperature 80 ~ 100 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the first extraction thing;
(2) 500 grams dry, Fructus Hordei Germinatus, 1000 grams, the fruit of Chinese magnoliavine, 1000 grams, mung bean, 500 grams, black soya bean, 500 grams, red bean and ginseng 500 grams are cut into 2 ~ 5mm section, drop into and extract tank, drop into the water that section weighs 10 times, stir 18 hours at temperature 80 ~ 100 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the second extraction thing;
(3) dry rhodiola root 500 grams is cut into 2 ~ 5mm section, drops into and extract tank, drop into the water that section weighs 10 times, stir 18 hours at temperature 80 ~ 100 DEG C, obtain after extracting thing and be cooled to normal temperature, obtain the 3rd and extract thing;
(4) extract thing, the second extraction thing and the 3rd extraction thing to mix described first, obtain extracting thing mixture, then filter press is utilized to be separated the solid-state powder extracted in thing mixture with centrifugal separator, utilize particulate matter in ultracentrifugation seperator separation extraction thing mixture and protein, obtain and extract thing for the first time, the rotating speed of described ultracentrifugation seperator is 15000 revs/min ~ 20000 revs/min;
(5) utilize active carbon filter, be separated fat constituent, benzene phenoloid, tannic acid composition in extraction of described first time thing, obtain second time and extract thing;
(6) utilize ultra micro order filter, be separated the nonactive macromolecule in described second time extraction thing, carbohydrate, microorganism, obtain and extract thing for the third time;
(7) utilize decompression concentrator, described third time is extracted thing and is concentrated to more than 10 Brix degrees, obtain and finally extract thing;
(8) by described final extraction thing, in 36 hours, be warmed up to 40 DEG C from-60 DEG C, relieve the effect of alcohol described in obtained raffinate.
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| CN201510208943.8A CN104783165A (en) | 2015-04-28 | 2015-04-28 | Method for preparing anti-alcohol raffinate from natural plant |
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| CN201510208943.8A CN104783165A (en) | 2015-04-28 | 2015-04-28 | Method for preparing anti-alcohol raffinate from natural plant |
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| CN104783165A true CN104783165A (en) | 2015-07-22 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080101848A (en) * | 2008-10-30 | 2008-11-21 | 김광수 | Herb extracts and functional food using the same for obviating and curing hangover |
| CN101904379A (en) * | 2010-07-23 | 2010-12-08 | 沁阳市百草坡山珍科技有限公司 | Sobering and liver protecting tea and preparation method thereof |
| CN103181598A (en) * | 2013-03-13 | 2013-07-03 | 冯素明 | Dealcoholic beverage |
| CN103445117A (en) * | 2013-09-16 | 2013-12-18 | 宁波市江东农茹生物科技有限公司 | Healthcare radix puerariae nutrition powder capable of preventing alcoholic liver injury |
| CN103751411A (en) * | 2013-10-25 | 2014-04-30 | 南通瑞普埃尔生物工程有限公司 | Rose alcohol effect dispelling capsule |
-
2015
- 2015-04-28 CN CN201510208943.8A patent/CN104783165A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080101848A (en) * | 2008-10-30 | 2008-11-21 | 김광수 | Herb extracts and functional food using the same for obviating and curing hangover |
| CN101904379A (en) * | 2010-07-23 | 2010-12-08 | 沁阳市百草坡山珍科技有限公司 | Sobering and liver protecting tea and preparation method thereof |
| CN103181598A (en) * | 2013-03-13 | 2013-07-03 | 冯素明 | Dealcoholic beverage |
| CN103445117A (en) * | 2013-09-16 | 2013-12-18 | 宁波市江东农茹生物科技有限公司 | Healthcare radix puerariae nutrition powder capable of preventing alcoholic liver injury |
| CN103751411A (en) * | 2013-10-25 | 2014-04-30 | 南通瑞普埃尔生物工程有限公司 | Rose alcohol effect dispelling capsule |
Non-Patent Citations (1)
| Title |
|---|
| 古今等: "解酒药物的研究进展", 《中国药物应用与检测》 * |
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