CN104771423B - A kind of method and relative medicine for being used to prepare facial neuritis medicine - Google Patents

A kind of method and relative medicine for being used to prepare facial neuritis medicine Download PDF

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CN104771423B
CN104771423B CN201510194843.4A CN201510194843A CN104771423B CN 104771423 B CN104771423 B CN 104771423B CN 201510194843 A CN201510194843 A CN 201510194843A CN 104771423 B CN104771423 B CN 104771423B
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oil
centipede
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CN104771423A (en
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张子青
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Abstract

The present invention provides a kind of method for being used to prepare facial neuritis medicine, the method is used as raw material using 48 parts of centipede, 8 12 parts of ceramic powder, 35 parts of azone, yellow lead 80 120, sesame oil 180 220, cost is low, effect is good, compared with conventional facial neuritis therapeutic modality, the patient in each stage can be made to eliminate slight illness within the shorter time.The prepared medicine of the present invention differs for only 1 to 9 day for initial patient, treatment cycle, and effective percentage reaches 100%, is significantly higher than the effective percentage of conventional therapy 90% or so;Also, sequelae person is stayed for facial neuritis, medicine of the invention can reach therapeutic purposes by activating downright bad nerve, and effective percentage reaches more than 80%, and having broken the course of disease just must be by the curable final conclusion of operative treatment ability more than 6 months.

Description

A kind of method and relative medicine for being used to prepare facial neuritis medicine
Technical field
The present invention relates to Chinese medicine, in particular to a kind of preparation method for the medicine for being used to treat facial neuritis And relative medicine.
Background technology
Facioplegia, is commonly called as facial neuritis, " facial paralysis ", is using facial expression muscle movement dysfunction as main feature A kind of common disease.General symptom is facial paralysis.It is a kind of common disease, frequently-occurring disease, it is from age limit.Patient is often The actions such as most basic lift eyebrow, eye closing, drum mouth can not all be completed.
The treatment of facial neuritis is often divided into described below several.
1st, drug therapy, early treatment are advocated with neurovascular dystrophy medicine and heavy dose of hormone.But excessive use hormone Many harmful effects may be brought to human body, and it is also to need more than two weeks that it, which can work, even using hormone Treatment cycle.
2nd, physical therapy, can use magnetic therapy, infrared ray in early days.Later stage can make facial muscle movement, but early stage disease, this facial muscle Motion exercise is not only unhelpful, is harmful on the contrary, and strong pleural muscle meat can be made too active.
3rd, acupuncture and moxibustion treatment.Acupuncture and moxibustion treatment can bring pain to human body, and the personnel for grasping acupuncture technique it is limited, it is irregular not Together, it is difficult to be widely popularized.
4th, operative treatment, for completeness facial paralysis, nerve excitability test threshold value both sides differ 3.5~4mA, facial nerve electrograph Loss is more than more than 90%, electromyogram without random electrical activity but have fibrillation, disease 3 weeks or to after 2 months still without it is any recover sign, Feasible facial nerve decompression.But operative treatment is for patients, distress level is big, and delay length, recovers slow.
Therefore, in conclusion at present both at home and abroad opposite it is neuritic treatment there are following problem:
1st, the conventional therapy course for the treatment of is grown, and is taken more than one month time under normal circumstances and can be recovered normal.
2nd, conventional therapy pain is more, and conventional therapy will endure the pain of the complex treatments such as acupuncture, vitamin B complex, dibazol more It is bitter.
3rd, conventional therapy side effect is big, the easy soft tissue injury of acupuncture and moxibustion therapy, causes local swelling infection etc., oral drugs Contain hormone medicine more, damage the immunity function of body.
4th, conventional therapy is once fail, and using other treatments instead will be more difficult, or even causes irreversible symptom, and the course of disease surpasses That spends 6 months then more will be treated by operation.
Although also there is the Chinese patent drug of some treatment facial neuritises, since effect is not fairly obvious, and treatment cycle is long, mouth The reasons such as sense difference are not easy to promote the use of.
Therefore, in the market needs one kind to have no toxic side effect, and can effectively treat the medicine of facial neuritis in a short time.
The content of the invention
There is dredging collateral, swelling and pain relieving, activate controlling for downright bad nerve fiber in view of the above-mentioned problems, present invention offer is a kind of Treat facial neuritis plaster and preparation method thereof.
The present invention combines the long-term clinical practice of inventor on the basis of secret prescription handed down in the family from generation to generation, refers to according to traditional Chinese medical science traditional theory Modern pharmacological research is achieved, and is carried out scientific allocation to former prescription, is formd with expelling wind and clearing away cold, heat-clearing dredging collateral, swelling and pain relieving Medicinal material presses theory of traditional Chinese medical science prescription, dispels its perverse trend, healthy tendency is recovered, channels and collaterals are unobstructed, activation is neural, so as to reach therapeutic purposes, The particularly downright bad effects on neural system of its activation, becomes infusive treatment facial neuritis sequelae (intractable facial neuritis) " new model ", has lighted the hope for the treatment of facial neuritis sequelae (intractable facial neuritis) patient.
Specifically, the present invention provides a kind of method for being used to prepare facial neuritis medicine, it is characterised in that institute The method of stating comprises the following steps:
Step 1), the yellow lead for taking the first scheduled volume, and it is carried out dehydrating;
Step 2), the centipede for taking the second scheduled volume, and it is placed on the pre- timing of heating first in the sesame oil of the 3rd scheduled volume Between;
Step 3), pull step 2) out and obtain residue in mixture, obtains medicine oil;
Step 4), further decoct obtained medicine oil under the first predetermined temperature;
Step 5), be gradually added into the yellow lead after step 1) processing in the medicine oil;
Step 6), obtain mixture by step 5) and be down to the second predetermined temperature;
The azone of step 7), the ceramic powder for adding the 4th scheduled volume in the resulting mixture and the 5th scheduled volume.
In a kind of preferred implementation, first scheduled volume is 80-120 by weight parts;Second scheduled volume For 4-8 by weight parts;3rd scheduled volume is 180-220 by weight parts;4th scheduled volume is 8- by weight 12 parts;5th scheduled volume is 3-5 by weight parts.
Yellow lead is carried out dehydrating in a kind of preferred implementation, in the step 1) and refers to yellow lead being put in device Heat drying is to bronzing in ware;
The step 2) includes heating the mixture of centipede and sesame oil 20-30 minutes, is in dark brown to centipede outside;
The step 3) is additionally included in the medicine residue is pulled out after, continue 5-15 minutes fried;
The oil droplet that the step 4) includes carrying out the medicine oil the further medicine oil is in pearl after oozing; When the temperature that the step 5) is included in the medicine oil reaches 300-330 DEG C, yellow lead is gradually added into while agitating, and When the given out white cigarette of reaction eliminates, stop heating;
When the step 6) is with including the temperature of the medicine oil being down to 60-70 DEG C 7), ceramic powder is added, is then added again Enter azone.
In a kind of preferred implementation, the method further includes:
Step 8):Cooling condensation is carried out to the step 7) the resulting product, it is predetermined to be placed in immersion second in cold water Time, obtains facial neuritis medicine.
In a kind of preferred implementation, the method further includes:
Step 9):The facial neuritis medicine that step 8) is obtained is dried in the shade surface moisture, fire insulation molten uniformly coats In on the substrate of predetermined shape, the plaster for being used for treating facial neuritis is formed.Substrate can use cloth or other gas permeable materials.
On the other hand, the present invention provides a kind of medicine for treating facial neuritis, it is characterised in that the medicine includes:Wu The ester extract of centipede or centipede, ceramic powder, azone, yellow lead, sesame oil.
In a kind of preferred implementation, the preparing raw material of the medicine includes 4-8 parts of centipede, 8-12 parts of ceramic powder, nitrogen 3-5 parts of ketone, yellow lead 80-120, sesame oil 180-220.
In a kind of preferred implementation, the medicine is to be based on using the preparing raw material in claim 1-5 arbitrarily It is prepared by the method described in one.
The optimum feed stock weight proportion of medicine of the present invention is:6 parts of centipede, 10 parts of ceramic powder, 3 parts of azone, 100 parts of yellow lead, 200 parts of sesame oil.
In a kind of preferred implementation, after step 3), the mixture also after the plaster (step 3) decocts) The middle water extract dried powder for adding following substances:5 parts of chrysanthemum, 8 parts of pueraria lobata, 12 parts of folium isatidis, 4 parts of radix glycyrrhizae and 9 parts windproof. In addition, the ester extract concentrate of following material is also added wherein:5 parts of the root of Dahurain angelica, 5 parts of cicada slough, 5 parts of stiff silkworm, 5 parts of Ligusticum wallichii.Here The ester extract concentrate being previously mentioned refers to adding above-mentioned substance into sesame oil or other oils the production for decocting and removing residue afterwards Thing.
Clinical drug of the present invention use the result shows that, have the advantage that:
It is raw material that the present invention, which selects Chinese medicine, and each component meets pharmaceutical control and administration law regulation.Controlled using the comprehensive function of each taste Chinese medicine Facial neuritis is treated, it is nontoxic to human body.Present invention application is convenient, and patient's pain is small, time saving and energy saving.The present invention is used alone i.e. Can, without coordinating other treatment.Short treating period, such as treats (particularly acupuncture), when taking 7 days or so under normal circumstances without other Between can recover normal, one or two people can fully recover 1 to 2 day time.
Conventional therapy once failure, use instead this method treatment (course of disease is no more than 1 year person) it is still valid, this is that one kind makes us emerging " new model " for the intractable facial neuritis for the treatment of put forth energy, is the hope of facial neuritis sequelae (intractable facial neuritis) patient.
The product of the present invention has good therapeutic effect to facial neuritis patient, and concrete condition is as follows:
Initial patient's (particularly not passing through acupuncture and moxibustion therapy person), treatment cycle differs for only 1 to 9 day, is substantially less than conventional control In the cycle (treatment cycle of conventional therapy general 1 month or so) for the treatment of, effective percentage reaches 100%, is significantly higher than conventional therapy Effective percentage 90% or so.Facial neuritis stays sequelae person (course of disease was more than 3 months), that is, is considered as facial nerve necrosis, particularly disease More than 6 months persons of journey, are the necrosis of facial nerve irreversibility, and the present invention also can reach therapeutic purposes by activating downright bad nerve, have Efficiency reaches more than 80%, and having broken the course of disease just must be by the curable final conclusion of operative treatment ability more than 6 months.The present invention into Work(treatment case includes more than 1 year patient of a course of disease, fully recovers after the product treatment of the present invention.
Brief description of the drawings
Fig. 1 is the preparation flow schematic diagram according to the medicine of one embodiment of the invention.
Embodiment
Embodiment one
In the present embodiment, preparing uses raw material as follows:6 parts of centipede, 10 parts of ceramic powder, 3 parts of azone, 100 parts of yellow lead, 200 parts of sesame oil, wherein, every part of content is 10g.
Specific pharmacy procedure is as follows:
Yellow lead is put in aluminum pot to do and is fried to bronzing, moisture in yellow lead is removed, puts spare after cool.
Centipede is put into the aluminum pot for fill sesame oil and is fried 20-30 minutes with slow boiling, when frying material, with Chinese tamarisk branch or ramulus mori Or Chinese scholartree branch is stirred continuously, and is heated evenly medicine, can decoct thoroughly, to reach the effective ingredient of preferably extraction medicine, when oil temperature reaches At 200 DEG C -250 DEG C or so, it is in dark brown outside centipede, when not carbonizing, i.e., the dregs of a decoction is pulled out with strainer, medicine oil is continued fried About ten minutes, minimize the impurity in medicine oil with the oxide evaporation for promoting sesame oil and medicine to produce, to improve The quality of plaster, prepares medicine oil.
With warm fire continue to decoct medicine oil to drip beading when (when oil temperature is up to 320 DEG C or so), put into yellow lead slowly, use at the same time Chinese tamarisk branch or ramulus mori or Chinese scholartree branch are ceaselessly stirred to a direction, when white cigarette eliminates, stop heating.
It is down to when medicine oil temperature when 60-70 is spent and adds ceramic powder, be eventually adding penetrant azone, with Chinese tamarisk branch or ramulus mori Or Chinese scholartree branch is ceaselessly stirred to beading of dripping to a direction.
Plaster is poured into 4000-5000ml cold water basins, is stirred continuously, it is become band, pinches and is kneaded into repeatedly after condensing Bulk, is put into cold water to soak to remove for 5-7 days and releases fire-toxin, and more renews water number daily, that is, the cream for the treatment of facial neuritis is made Medicine.
Dry in the shade after surface moisture, fire insulation molten, spreads out in the cloth of 5 × 7cm ellipses, large size stand plaster 10g per note, trumpet Per note 8g, circular shaped plaster diameter 2cm (2g).
Plaster is affixed on Ipsilateral face, and with pain person after ear, screen wind scoop sticks on diameter 2cm (2g) circular shaped plaster, with eye It cannot close, the sagging person in canthus, temple stick on diameter 2cm (2g) circular shaped plaster.
To show the neuritic magical therapeutic effect in medicine opposite of the present invention, citing shows:
Model case:
X is opened, it is male, 19 years old, first visit on December 23 in 2013.Left side facial paralysis 3 days, finds when early morning washes one's face before 3 days Left eye cannot close, and not control, look into left volume line and disappear, frown, close mesh, the drum cheek cannot, nasolabial groove is askew to the right.
Losing money in a business, the prepared plaster of invention in Ipsilateral face, fully recover by totally 1 patch (2 days), treatment.
King X, female, 43 years old, first visit on the 17th in 08 month in 2009.Left side facial paralysis more than 1 year, sends out when early morning washes one's face before 1 year Existing left eye cannot close, and (apply prednisone, vitamin B complex, methylcobalamin tablet, dibazol etc., another acupuncture to hospital's conventional therapy then Treatment 8 months), the readme state of an illness slightly improves, and facial paralysis is slightly led just.Look into left volume line to disappear, it is impossible to it is light to close mesh, the drum cheek completely Micro- gas leakage, nasolabial groove are askew to the right.
Losing money in a business, the prepared plaster of invention in Ipsilateral face, fully recover by totally 23 patch, treatment.
Pan X, man, 32 years old, first visit on the 06th in 07 month in 2013.Right side facial paralysis more than 40 days, slept air-conditioning after drinking before 40 days , there is pain after the ear of right side in Fang Hou, and right side corners of the mouth leakage rice grain, carries out drug therapy (medicine name and dosage are unknown) and pin then when having a meal Moxibustion treatment is treated 1 month, and the state of an illness slightly improves, and facial paralysis is slightly led just.Right volume line is looked into disappear, it is impossible to mesh, drum cheek gas leakage are closed completely, Nasolabial groove is askew to the left.
Losing money in a business, the prepared plaster of invention in Ipsilateral face, fully recover by totally 6 patch (20 days), treatment.
Therefore, clinical test demonstrates, and medicine of the invention can effectively treat facial neuritis, it is directed to various illness The patient of duration has positive effect.
Embodiment two
In the present embodiment, using the preparation method similar with embodiment one, it simply have adjusted the proportioning of raw material.At this In embodiment, use raw material as follows:5 parts of centipede, 12 parts of ceramic powder, 5 parts of azone, 110 parts of yellow lead, 180 parts of sesame oil, chrysanthemum 5 Part, 8 parts of pueraria lobata, 12 parts of folium isatidis, 4 parts of radix glycyrrhizae, 9 parts windproof, 5 parts of the root of Dahurain angelica, 5 parts of cicada slough, 5 parts of stiff silkworm, 5 parts of Ligusticum wallichii.
In the present embodiment, preparation method and embodiment one are essentially identical, are simply pulled out by centipede residue from sesame oil Afterwards, the water extract dried powder or water extracting liquid of following substances are added also in the mixture after decocting:5 parts of chrysanthemum, Pueraria lobota 8 parts of root, 12 parts of folium isatidis, 4 parts of radix glycyrrhizae and 9 parts windproof.Specific method is to add above-mentioned material in pure water, and heating decocts 1-2 hour, then reject residue aqueous solution is dried, obtain corresponding powder or concentrate.
In addition, the ester extract concentrate of following material is also added wherein:5 parts of the root of Dahurain angelica, 5 parts of cicada slough, 5 parts of stiff silkworm, Ligusticum wallichii 5 Part.Ester extract concentrate mentioned herein refers to adding above-mentioned substance in sesame oil or other Esters and decocts and remove Product after residue.
By the way of in embodiment two, made plaster has effects that significantly to treat facial neuritis, and should Formula is more easy to absorb using rear patient, and acceptance is more preferable.
In another preferred implementation, the water extract of 8-11 parts of lycopodium calvatum is additionally added in the mixture.
In addition, it is necessary to explanation, although defining the quality of each raw material in claims, art technology Personnel are it should be understood that the component of each raw material can be increased or decreased with equal proportion.It should also be noted that, the present invention is used Raw material be conventional commercially available Chinese medicine, be not described in detail here.
It should be noted that, although the present invention is described in detail above in conjunction with specific embodiments and the drawings, but It is that above description only schematically illustrates, in order to those skilled in the art's the understanding of the present invention, shown in figure The detail of part is not the restriction to invention protection domain.Those skilled in the art it should also be understood that above-described embodiment also only Only it is the explanation to the exemplary implementation of the present invention, is not limiting the scope of the invention.

Claims (4)

  1. A kind of 1. method for being used to prepare facial neuritis medicine, it is characterised in that the method is made of following step:
    Step 1), take the yellow lead of the first scheduled volume, and it is carried out dehydrating;
    Step 2), take the centipede of the second scheduled volume, and be placed in the sesame oil of the 3rd scheduled volume and be evenly heated 20-30 minutes;
    Step 3), do not carbonized constantly in dark brown outside 200-250 DEG C and centipede when sesame oil temperature reaches, pull step 2 out)Institute The residue in mixture is obtained, obtains medicine oil;
    Step 4), obtained medicine oil is further decocted it is 8-10 minutes lasting;
    Step 5), in the medicine oil be gradually added into step 1)Yellow lead after processing;
    Step 6), by step 5)Obtained mixture is down to 60-70 DEG C;
    Step 7), in the resulting mixture add the 4th scheduled volume ceramic powder and the 5th scheduled volume azone,
    Wherein, first scheduled volume is 80-120 by weight parts;Second scheduled volume is 4-8 by weight parts;It is described 3rd scheduled volume is 180-220 by weight parts;4th scheduled volume is 8-12 by weight parts;5th scheduled volume is 3-5 by weight parts, obtained plaster is poured into cold water basin, immersion after drying in the shade, is spread out in ellipse for 5-7 days respectively except releasing fire-toxin Cloth and circular cloth in, oval plaster and circular shaped plaster is respectively prepared, the facial neuritis medicine is ellipse when in use Circular shaped plaster be affixed on Ipsilateral face, with pain person after ear, screen wind scoop sticks on circular shaped plaster, cannot be closed with eye, canthus it is sagging Person, temple stick on circular shaped plaster.
  2. 2. the method according to claim 1 for being used to prepare facial neuritis medicine, it is characterised in that
    The step 1)In yellow lead be carried out dehydrating refer to yellow lead being put in vessel heat drying to bronzing;
    The step 2)It is in dark brown to centipede outside including being heated 20-30 minutes to the mixture of centipede and sesame oil;
    The step 3)It is included in after the medicine residue is pulled out, continues 5-15 minutes fried;
    The step 4)Oil droplet including carrying out the further medicine oil to the medicine oil is in pearl after oozing;
    The step 5)When being included in the temperature of the medicine oil and reaching 300-330 DEG C, yellow lead is gradually added into while agitating, and And when the given out white cigarette of reaction eliminates, stop heating;
    The step 6)With 7)During including the temperature of the medicine oil being down to 60-70 DEG C, ceramic powder is added, then adds nitrogen Ketone.
  3. A kind of 3. medicine for treating facial neuritis, it is characterised in that the medicine by the ester extract of centipede or centipede, ceramic powder, Azone, yellow lead, sesame oil are made, and the preparing raw material of the medicine includes 4-8 parts of centipede, 8-12 parts of ceramic powder, 3-5 parts of azone, Huang 80-120 parts red, 180-220 parts of sesame oil, the medicine is prepared in the following way:
    The described method includes following step:
    Step 1), take 80-120 parts of yellow lead, and it is carried out dehydrating;
    Step 2), take 4-8 parts of centipedes, and be placed in 180-220 portions of sesame oil and be evenly heated 20-30 minutes;
    Step 3), when sesame oil temperature reaches 200-250 DEG C, pull step 2 out)Residue in obtained mixture, obtains medicine oil;
    Step 4), obtained medicine oil is further decocted it is 8-10 minutes lasting;
    Step 5), in the medicine oil be gradually added into step 1)Yellow lead after processing;
    Step 6), by step 5)Obtained mixture is down to 60-70 DEG C;
    Step 7), add 8-12 parts of ceramic powders and 3-5 parts of azones in the resulting mixture.
  4. 4. the medicine for the treatment of facial neuritis according to claim 3, it is characterised in that the preparing raw material bag of the medicine Include:6 parts of centipede, 10 parts of ceramic powder, 3 parts of azone, 100 parts of yellow lead, 200 parts of sesame oil.
CN201510194843.4A 2015-04-22 2015-04-22 A kind of method and relative medicine for being used to prepare facial neuritis medicine Active CN104771423B (en)

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CN105663979A (en) * 2015-12-31 2016-06-15 泰山医学院 External-apply plaster for treating facial paralysis caused by head injury, and preparation method thereof
CN105770333A (en) * 2016-03-14 2016-07-20 杨朋 Medicinal composition for treating facial neuritis
CN106039006A (en) * 2016-06-29 2016-10-26 杨晨阳 Traditional Chinese medicine composition for treating facial neuritis and preparation method of traditional Chinese medicine composition

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1393235A (en) * 2001-06-26 2003-01-29 利津县第二人民医院 Plaster for treating facial neuritis and its preparing process

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CN101912572B (en) * 2010-07-30 2012-06-27 崔宝海 Multi-effect external plaster
CN102423364A (en) * 2011-11-29 2012-04-25 丁荣松 Straightening plaster for treating facial paralysis and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1393235A (en) * 2001-06-26 2003-01-29 利津县第二人民医院 Plaster for treating facial neuritis and its preparing process

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