CN104758662A - Qi-regulating and swelling-dispersing preparation for nasopharynx cancer and preparation method thereof - Google Patents
Qi-regulating and swelling-dispersing preparation for nasopharynx cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a qi-regulating and swelling-dispersing preparation for nasopharynx cancer, which is mainly prepared from following raw material medicines, by weight: 10-20 parts of fructus xanthii, 9-16 parts of livistona chinensis seeds, 15-20 parts of rhizome imperata cylindrica, 15-20 parts of stephania tetrandra, 6-12 parts of oroxylum indicum, 10-20 parts of dandelion, 8-16 parts of stir-fried fructus gardeniae, 10-15 parts of rhizoma bolbostemmae, 9-15 parts of medical stone, 8-12 parts of sambucus chinensis roots, 6-9 parts of scutellaria barbata, 5-12 parts of prunella vulgaris, 9-15 parts of calcined oysters, 6-10 parts of mangifera indica pits and 15-20 parts of nodus nelumbinis rhizomatis. The preparation is prepared from pure traditional Chinese medicines, is stable in components in each dosage and is reliable in curative effects. The preparation is researched according to pathogenesis of the nasopharynx cancer, has functions of clearing heat and promoting urination, dispelling liver and regulating qi, dissipating bind and dispersing swelling. A clinical test proves that the preparation is good and quick in curative effects and can effectively improve discomfort symptoms in patients.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of nasopharyngeal carcinoma and to regulate the flow of vital energy detumescence preparation and method for making.
Background technology
Nasopharyngeal carcinoma refers to the malignant tumor betiding cavum nasopharyngeum top and sidewall.Be one of China's malignant tumor occurred frequently, sickness rate is first of ear,nose & throat malignant tumor.Because nasopharynx part anatomical position is hidden, nasopharyngeal carcinoma early symptom is not true to type.Common sympton has: 1. sniffle: can occur in early days being with blood or blowing out in tears in retraction tears being with blood, cut in and out, how not cause patient to pay attention to, the continuous increase of tumor body can block nostril, causes nasal obstruction, begins as one-sided, bilateral then; 2. ear's symptom: tumor betides pharyngeal recess person, can oppress in early days or block pharyngeal opening of auditory tube, and cause this pick up the ears ring, deafness and auditory dysesthesia, hydrotympanum, clinical easy mistaken diagnosis is secretory otitis media; 3. cervical lymph node enlargement: Cervical Lymph Node Metastasis person is more common is that starting symptom accounts for 60% with deradenoncus, and the lymph of transfer enlargement becomes group's lymph node in throat depth portion, increase in Progressive symmetric erythrokeratodermia, the hard inertia of matter, without tenderness, begin, for one-sided, then to develop into bilateral; 4. cranial nerve symptom: tumor body by foramen lacerum Intracranial invasion, often first invades V, VI cranial nerve through Ipsilateral pharyngeal recess, then involves II, III, IV cranial nerve and has a headache, facial numbness, the cranial nerve such as eyeball abduction is limited, the ptosis are got involved symptom; 5. metastasis: transfer can appear in advanced NPC, and common person has bone, lung, liver etc.Nasopharyngeal carcinoma major part is low differentiated squamous-cell carcinomas, and has Medium sensitivity to radiotherapy, and radiotherapy is the first-selected Therapeutic Method of nasopharyngeal carcinoma.But to comparatively well-differentiated carcinoma, the case of the more late and recurrence after radiotherapy of the course of disease, also needs to take excision and chemotherapy means.Publication No. CN 103845613 A(application number 201210532689.3) Chinese patent literature disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma, it is by Herba Solani Nigri 20-40 gram of weight portion, Radix Sophorae Tonkinensis 15-25 gram, Pseudobulbus Cremastrae Seu Pleiones 15-25 gram, and pulverizing is made.Publication No. CN 103071112 A(application number 201310001820.8) Chinese patent literature disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma, by the Radix vitis romanetii 8-12 of weight proportion, Fructus Aurantii Immaturus 13-17, Fructus Akebiae 28-32, Radix Ginseng 4-15, Rhizoma Gymnadeniae 4-15, Rhizoma Coptidis 13-17, Oletum Trogopterori 8-12, Herba Duchesneae Indicae 28-32, little red Bulbus Allii root 8-12, Rhizoma Chuanxiong 13-17, Rhizoma Sparganii 4-15, Rhizoma Curcumae 13-17, huechys 28-32, Radix Aristolochiae Kaempferi 4-15, Herba Artemisiae Anomalae 8-12, Radix Tinosporae 28-32, Herba Houttuyniae 1-5, Radix seu folium abelmoschi moschati 8-12, Aster oreophilus Franch 4-15, Herba Catharanthi Rosei 1-5, Nidus Vespae 28-32, Herba Polygoni cymosi 13-17 forms.Publication No. CN 104189558 A(application number 201410383072.9) Chinese patent literature disclose a kind of Chinese medicine decoction for the treatment of nasopharyngeal carcinoma, be made up of the Chinese medicine such as Pericarpium Zanthoxyli 15-25g, Herba Xanthii 45-55g, Flos Magnoliae 28-32g, Squama Manis 60-80g, Radix Angelicae Dahuricae 18-22g, eupolyphoge sinensis 25-35g, Semen Persicae 25-35g, Formica fusca 90-110g, Scolopendra 6-10 bar, Radix Peucedani 28-32g, Agkistrodon 40-60g, Herba Sedi 28-35g, Herba Lysimachiae 28-32g, Fructus Lycii 25-35g, Radix Glycyrrhizae 8-12g, Radix Cucurbitae 8-12g, unfolded tender leaf of Sinocalamus affinis (Rendle) Mcclure 4-6g, Radix Rumicis Crispi 1-3g and Castanea 4-6g.
All there is many weak points in the medicine of Current therapeutic nasopharyngeal carcinoma, as Western medicine side effect is large, dependency is strong, and long-term taking injures internal organs, and Chinese medicine takes effect slowly, DeGrain.Therefore, the research strengthening Chinese medicine nasopharyngeal carcinoma aspect is further needed.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, easily a kind of nasopharyngeal carcinoma of clothes is regulated the flow of vital energy detumescence preparation and preparation method thereof for a long time.This Chinese medicine composition determined curative effect and having no side effect.
Technical scheme of the present invention is:
A kind of nasopharyngeal carcinoma is regulated the flow of vital energy detumescence preparation, is prepared from, is weight portion: Fructus Xanthii 10-20 primarily of following bulk drugs, Chinese fanpalm seed 9-16, Rhizoma Imperatae 15-20, Radix Stephaniae Tetrandrae 15-20, Semen Oroxyli 6-12, Herba Taraxaci 10-20, Fructus Gardeniae (stir-fry) 8-16, Rhizoma Bolbostematis 10-15, Maifanitum 9-15, Radix Sambuci Chiensis 8-12, Herba Scutellariae Barbatae 6-9, Spica Prunellae 5-12, Concha Ostreae (calcined) 9-15 Fructus Mangifera Indicae core 6-10, Nodus Nelumbinis Rhizomatis 15-20.
In preferred scheme, Fructus Xanthii 12-18, Chinese fanpalm seed 11-14, Rhizoma Imperatae 16-19, Radix Stephaniae Tetrandrae 16-19, Semen Oroxyli 8-10, Herba Taraxaci 12-18, Fructus Gardeniae (stir-fry) 10-14, Rhizoma Bolbostematis 11-14, Maifanitum 11-13, Radix Sambuci Chiensis 9-11, Herba Scutellariae Barbatae 7-8, Spica Prunellae 7-10, Concha Ostreae (calcined) 11-13 ， Fructus Mangifera Indicae core 7-9, Nodus Nelumbinis Rhizomatis 17-18.
Be more preferably, Fructus Xanthii 15, Chinese fanpalm seed 12, Rhizoma Imperatae 17.5, Radix Stephaniae Tetrandrae 17.5, Semen Oroxyli 9, Herba Taraxaci 15, Fructus Gardeniae (stir-fry) 12, Rhizoma Bolbostematis 12.5, Maifanitum 12, Radix Sambuci Chiensis 10, Herba Scutellariae Barbatae 7.5, Spica Prunellae 8.5, Concha Ostreae (calcined) 12 ， Fructus Mangifera Indicae core 8, Nodus Nelumbinis Rhizomatis 17.5.
The regulate the flow of vital energy preparation method of detumescence preparation decoction of described a kind of nasopharyngeal carcinoma is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries, pulverize, obtain medicated powder;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) Concha Ostreae (calcined) and Maifanitum are soaked 20 minutes, be heated to boiling, add again pick decontamination Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae, Fructus Mangifera Indicae core and step (2) (3) made crude drug, (preferred, a turn little fire decocts 22-28 minute to turn little fire decoction 20-30 minute; Be more preferably, turn little fire and decoct 25 minutes), filter, obtained filtrate;
(5) step (1) made medicated powder is joined in step (4) made filtrate, stir evenly, obtain decoction.
Described a kind of nasopharyngeal carcinoma is regulated the flow of vital energy the preparation method of detumescence preparation decoction, the 5-8 of step (4) amount of water total raw material medicine quality doubly (preferred, amount of water be the 6-7 of total raw material medicine quality doubly, be more preferably, amount of water is 6.5 times of total raw material medicine quality).
The preparation method of described granule is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out, pulverizes together with step (1) (2) made crude drug;
(4) Concha Ostreae (calcined) and Maifanitum are added up the water soaking 20 minutes of crude drug quality 6.5 times, be heated to boiling, add again pick impurity Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae is with Fructus Mangifera Indicae core, (preferred, a turn little fire decocts 22-28 minute to turn little fire decoction 20-30 minute; Be more preferably, turn little fire and decoct 25 minutes), filter, obtained filtrate, filtering residue is for subsequent use;
(5) by step (4) remaining filtering residue, add water and do not have crude drug 3cm, big fire is boiled rear little fire and is decocted, filter, merge with step (4) made filtrate, concentrating under reduced pressure, spraying dry, pulverize after and step (3) made medicated powder mix, add dextrin and starch slurry, soft material processed, granulation wet granular crosses 14 mesh sieves, drying, granulate, obtains granule.
Described a kind of nasopharyngeal carcinoma is regulated the flow of vital energy the preparation method of detumescence preparation granules agent, and step (5) big fire is boiled rear little fire and decocted 15-25 minute (preferred, big fire is boiled rear little fire and decocted 17-23 minute; Be more preferably, big fire is boiled rear little fire and is decocted 20 minutes).
The preparation method of described pill is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) by Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae He Fructus Mangifera Indicae core decontamination, cleaning, drying, pulverized 60-80 mesh sieve (preferred together with step (1) (2) (3) made crude drug, pulverized 70 mesh sieves), obtained medicated powder;
(5) by Concha Ostreae (calcined) and Maifanitum removing impurity, put into pot, add the water of both gross masses 7 times, big fire is boiled rear little fire and is decocted, filter, obtain filtrate, step (4) made medicated powder is added in filtrate, stirs evenly, spraying dry, pulverize, by the metering of made dry thing powder according to 0.1-0.3g/ ball (preferred 0.2g/ ball), make pill according to the preparation for processing of pill.
Described a kind of nasopharyngeal carcinoma is regulated the flow of vital energy the preparation method of detumescence preparation pill, step (5) big fire boil rear little fire decoct 30-40 minute (preferred, turn little fire and decoct 32-38 minute; Be more preferably, turn little fire and decoct 35 minutes).
The preparation method of described capsule is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) by Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae He Fructus Mangifera Indicae core decontamination, cleaning, drying, pulverize and sieve together with step (1) (2) (3) made crude drug, obtained medicated powder;
(5) by Concha Ostreae (calcined) and Maifanitum removing impurity, put into pot, add the water of both gross masses 7 times, big fire is boiled rear little fire decoction and (preferably, is turned little fire and decoct 32-38 minute for 30-40 minute; Be more preferably, turn little fire and decoct 35 minutes), filter, obtain filtrate, step (4) made medicated powder is added in filtrate, stirs evenly, spraying dry, pulverize, mix with pharmaceutical excipients, soft material processed, make uniform granule, incapsulate, obtain capsule.
Described a kind of nasopharyngeal carcinoma is regulated the flow of vital energy the preparation method of detumescence preparation capsule, step (4) pulverize 100-220 mesh sieve (preferred, pulverized 120-200 mesh sieve; Be more preferably, pulverized 160 mesh sieves).
A kind of nasopharyngeal carcinoma provided by the invention regulates the flow of vital energy detumescence according to traditional Chinese medical science principle of medication, scientific composition, and preparation is simple, products made thereby safety.In addition, excellent results of the present invention also shows:
1, product of the present invention is pure Chinese medicinal preparation, and each dosage form components is stablized, and curative effect is reliable;
2, this prescription develops according to nasopharyngeal carcinoma pathogenesis, has the effects such as clearing away heat and promoting diuresis, depressed liver-energy dispersing and QI regulating, mass dissipating and swelling eliminating;
3, the present invention is through clinical verification, good effect, instant effect, can effectively improve patient's malaise symptoms.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1a kind of nasopharyngeal carcinoma is regulated the flow of vital energy detumescence preparation, is prepared from (every part of 10g): Fructus Xanthii 10 parts, Chinese fanpalm seed 9 parts primarily of following bulk drugs, Rhizoma Imperatae 15 parts, Radix Stephaniae Tetrandrae 15 parts, Semen Oroxyli 6 parts, Herba Taraxaci 10 parts, Fructus Gardeniae (stir-fry) 8 parts, Rhizoma Bolbostematis 10 parts, Maifanitum 9 parts, Radix Sambuci Chiensis 8 parts, Herba Scutellariae Barbatae 6 parts, Spica Prunellae 5 parts, Concha Ostreae (calcined) 9 Fen ， Fructus Mangifera Indicae core 6 parts, Nodus Nelumbinis Rhizomatis 15 parts.
The regulate the flow of vital energy preparation method of detumescence preparation decoction of above-mentioned a kind of nasopharyngeal carcinoma is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 17 minutes, take out, dry, pulverize, obtain medicated powder;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, vexed 3 hours, exhausts remaining soup, pulls out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) Concha Ostreae (calcined) and Maifanitum are added up the water soaking 20 minutes of crude drug quality 6.5 times, be heated to boiling, add again pick decontamination Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae, Fructus Mangifera Indicae core and step (2) (3) made crude drug, turn little fire to decoct 25 minutes, filter, obtained filtrate;
(5) step (1) made medicated powder is joined in step (4) made filtrate, stir evenly, obtain decoction.
embodiment 2a kind of nasopharyngeal carcinoma is regulated the flow of vital energy detumescence preparation, is prepared from (every part of 10g): Fructus Xanthii 20 parts, Chinese fanpalm seed 16 parts primarily of following bulk drugs, Rhizoma Imperatae 20 parts, Radix Stephaniae Tetrandrae 20 parts, Semen Oroxyli 12 parts, Herba Taraxaci 20 parts, Fructus Gardeniae (stir-fry) 16 parts, Rhizoma Bolbostematis 15 parts, Maifanitum 15 parts, Radix Sambuci Chiensis 12 parts, Herba Scutellariae Barbatae 9 parts, Spica Prunellae 12 parts, Concha Ostreae (calcined) 15 Fen ， Fructus Mangifera Indicae core 10 parts, Nodus Nelumbinis Rhizomatis 20 parts.
The regulate the flow of vital energy preparation method of detumescence preparation granules agent of a kind of nasopharyngeal carcinoma is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 17 minutes, take out, dry;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, vexed 3 hours, exhausts remaining soup, pulls out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out, pulverizes together with step (1) (2) made crude drug;
(4) Concha Ostreae (calcined) and Maifanitum are added up the water soaking 20 minutes of crude drug quality 6.5 times, be heated to boiling, add again pick impurity Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae is with Fructus Mangifera Indicae core, turn little fire to decoct 25 minutes, filter, obtained filtrate, filtering residue is for subsequent use;
(5) by step (4) remaining filtering residue, add water and do not have crude drug 3cm, big fire is boiled rear little fire and is decocted 20 minutes, filter, merge with step (4) made filtrate, concentrating under reduced pressure, spraying dry, pulverize after and step (3) made medicated powder mix, add dextrin and starch slurry, soft material processed, granulation wet granular crosses 14 mesh sieves, drying, granulate, obtains granule.
Model case: xxx, man, 60 years old.Main suit: found before 3 years and suffer from nasopharyngeal carcinoma, symptom has headache, intermittent nasal obstruction, pharyngalgia, tinnitus, deafness, rear chemotherapy, the state of an illness is controlled, and symptom takes a turn for the better, nearly half a year, without the appearance dysphagia of obvious inducement, binocular diplopia, visual deterioration, medical check, white and thin fur, soft pulse is weak, and two neck has lump, and on the left of nasopharynx, there is Semen arachidis hypogaeae large aphtha type neoplasm at pharyngeal recess place, biopsy is pleomorphic carcinoma, recurrent nasopharyngeal carcinoma.
Take a kind of nasopharyngeal carcinoma of the present embodiment gained to regulate the flow of vital energy detumescence preparation capsule, adopt every day 3 times, each 4, with warm water delivery service, 30 days courses for the treatment of.After taking 40 days, patient's malaise symptoms takes a turn for the better, and after taking two courses for the treatment of, patients' visual recovery is close to normal, and dysphagia is obviously improved, self-induction mass reduction, and after taking four courses for the treatment of, on the left of nasopharynx, the neoplasm at pharyngeal recess place diminishes, rear drug withdrawal, patient experiences stable disease.
embodiment 3a kind of nasopharyngeal carcinoma is regulated the flow of vital energy detumescence preparation, is prepared from (every part of 10g): Fructus Xanthii 12 parts, Chinese fanpalm seed 11 parts primarily of following bulk drugs, Rhizoma Imperatae 16 parts, Radix Stephaniae Tetrandrae 16 parts, Semen Oroxyli 8 parts, Herba Taraxaci 12 parts, Fructus Gardeniae (stir-fry) 10 parts, Rhizoma Bolbostematis 11 parts, Maifanitum 11 parts, Radix Sambuci Chiensis 9 parts, Herba Scutellariae Barbatae 7 parts, Spica Prunellae 7 parts, Concha Ostreae (calcined) 11 Fen ， Fructus Mangifera Indicae core 7 parts, Nodus Nelumbinis Rhizomatis 17 parts.
The regulate the flow of vital energy preparation method of detumescence preparation pill of a kind of nasopharyngeal carcinoma is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 17 minutes, take out, dry;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, vexed 3 hours, exhausts remaining soup, pulls out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) by Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae He Fructus Mangifera Indicae core decontamination, cleaning, drying, pulverized 70 mesh sieves together with step (1) (2) (3) made crude drug, obtained medicated powder;
(5) by Concha Ostreae (calcined) and Maifanitum removing impurity, put into pot, add the water of both gross masses 7 times, big fire is boiled rear little fire and is decocted 35 minutes, filter, obtain filtrate, step (4) made medicated powder is added in filtrate, stirs evenly, spraying dry, pulverize, by made dry thing powder according to the metering of 0.2g/ ball, make pill according to the preparation for processing of pill.
Model case: xxx, female, 50 years old.Main suit: occur nasal obstruction the year before, insults tinnitus and auditory dysesthesia, found before half a year that there is egg yolk size lump cervical region both sides, dysphagia, medical check then, red tongue tongue is few, thready and rapid pulse, cervical region left and right sides Tumor size is 4 × 7 × 2cm and 3 × 6 × 1cm respectively, finds there is Semen arachidis hypogaeae size cauliflower-like neoplasm every trailing edge in patient's nasopharynx part, biopsy is large cell carcinoma, is diagnosed as nasopharyngeal carcinoma.
Take a kind of nasopharyngeal carcinoma of the present embodiment gained to regulate the flow of vital energy the agent of detumescence preparation granules, every day 3 times, each one bag (5g), warm boiled water, 30 days courses for the treatment of.After taking a course for the treatment of, patient tinnitus alleviates, and nasal obstruction is improved, and after taking three courses for the treatment of, patient's malaise symptoms disappears substantially, and the obvious deliquescing of self-induction lump is reduced, and two courses for the treatment of are taken in rear patient's consolidation, and lump disappears, and patient fully recovers.
embodiment 4a kind of nasopharyngeal carcinoma is regulated the flow of vital energy detumescence preparation, is prepared from (every part of 10g): Fructus Xanthii 18 parts, Chinese fanpalm seed 14 parts primarily of following bulk drugs, Rhizoma Imperatae 19 parts, Radix Stephaniae Tetrandrae 19 parts, Semen Oroxyli 10 parts, Herba Taraxaci 18 parts, Fructus Gardeniae (stir-fry) 14 parts, Rhizoma Bolbostematis 14 parts, Maifanitum 13 parts, Radix Sambuci Chiensis 11 parts, Herba Scutellariae Barbatae 8 parts, Spica Prunellae 10 parts, Concha Ostreae (calcined) 13 Fen ， Fructus Mangifera Indicae core 9 parts, Nodus Nelumbinis Rhizomatis 18 parts.
The regulate the flow of vital energy preparation method of detumescence preparation capsule of a kind of nasopharyngeal carcinoma is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 17 minutes, take out, dry;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, vexed 3 hours, exhausts remaining soup, pulls out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) by Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae He Fructus Mangifera Indicae core decontamination, cleaning, drying, pulverized 160 mesh sieves together with step (1) (2) (3) made crude drug, obtained medicated powder;
(5) by Concha Ostreae (calcined) and Maifanitum removing impurity, put into pot, add the water of both gross masses 7 times, big fire is boiled rear little fire and is decocted 35 minutes, filters, obtains filtrate, step (4) made medicated powder is added in filtrate, stirs evenly, spraying dry, pulverize, mix with pharmaceutical excipients, soft material processed, make uniform granule, incapsulate, obtain capsule.
Model case: xxx, man, 43 years old.Time recent, sense nasal obstruction, fatigue and asthenia, occasionally have headache, pharyngalgia, expectoration with the blood streak, medical check, red tip of the tongue tongue is greasy in vain, slippery and rapid pulse, finds that nasopharynx right hand top has Semen Pisi sativi size neoplasm, two necks do not touch lymphnode metastatic, and nasopharynx part biopsy is large cell carcinoma, is diagnosed as nasopharyngeal carcinoma.
Take a kind of nasopharyngeal carcinoma of the present embodiment gained to regulate the flow of vital energy detumescence preparation pill, adopt every day 3 times, each 4-6 grain, with warm water delivery service, 30 days courses for the treatment of.After taking 20 days, patient's nasal obstruction, headache, pharyngalgia alleviates, and expectoration is without the blood streak, and after taking two courses for the treatment of, nasopharynx right hand top mays be seen indistinctly neoplasm, and after taking four courses for the treatment of, patient is without malaise symptoms, and self-induction is fully recovered, and rear drug withdrawal, follows up a case by regular visits in 1 year, do not have recurrence.
embodiment 5a kind of nasopharyngeal carcinoma is regulated the flow of vital energy detumescence preparation, is prepared from (every part of 10g): Fructus Xanthii 15 parts, Chinese fanpalm seed 12 parts primarily of following bulk drugs, Rhizoma Imperatae 17.5 parts, Radix Stephaniae Tetrandrae 17.5 parts, Semen Oroxyli 9 parts, Herba Taraxaci 15 parts, Fructus Gardeniae (stir-fry) 12 parts, Rhizoma Bolbostematis 12.5 parts, Maifanitum 12 parts, Radix Sambuci Chiensis 10 parts, Herba Scutellariae Barbatae 7.5 parts, Spica Prunellae 8.5 parts, Concha Ostreae (calcined) 12 Fen ， Fructus Mangifera Indicae core 8 parts, Nodus Nelumbinis Rhizomatis 17.5 parts.
The regulate the flow of vital energy preparation method of detumescence preparation decoction of a kind of nasopharyngeal carcinoma is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 17 minutes, take out, dry, pulverize, obtain medicated powder;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, vexed 3 hours, exhausts remaining soup, pulls out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) Concha Ostreae (calcined) and Maifanitum are added up the water soaking 20 minutes of crude drug quality 6.5 times, be heated to boiling, add again pick impurity Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae, Fructus Mangifera Indicae core and step (2) (3) made crude drug, turn little fire to decoct 25 minutes, filter, obtained filtrate;
(5) step (1) made medicated powder is joined in step (4) made filtrate, stir evenly, obtain decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Xanthii: base is former: be the fruit of feverfew Herba Xanthii band involucre.Nature and flavor: pungent, bitter, temperature; Poisonous.Gui Jing: return lung meridian.Function cures mainly: Fructus Xanthii: loose wind dehumidifying, clearing the nasal passage.For headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.
Chinese fanpalm seed: base is former: be the seed of babassu Semen livistonae chinensis.Chemical composition: containing phenols, reducing sugar, tannin, triacylglycerol, aminoacid: lysine, serine, arginine, proline, tyrosine, valine, isoleucine, phenylalanine, sugar, vitamin C and ascorbic acid.Nature and flavor: sweet, bitter, flat, mild toxicity.Function cures mainly: blood circulation promoting and blood stasis dispelling, hard masses softening and resolving.Main chronic hepatitis, lump in the abdomen.
Rhizoma Imperatae: base is former: be the dry rhizome of grass Herba Imperatae.Nature and flavor: sweet, cold.Gui Jing: return lung, stomach, urinary bladder channel.Function cures mainly: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.
Radix Stephaniae Tetrandrae: base is former: be the dry root of menispermaceous plants Radix stephaniae tetrandrae.Nature and flavor: bitter, cold.Gui Jing: return bladder, lung meridian.Function cures mainly: inducing diuresis to remove edema, wind-expelling pain-stopping.For edema beriberi, dysuria, eczema sore, rheumatic arthralgia; Hypertension.
Semen Oroxyli: base is former: be the dry mature seed of Bignoniaceae plant oroxylum indicum.Nature and flavor: bitter, sweet, cool.Gui Jing: return lung, liver, stomach warp.Function cures mainly: removing heat from the lung and relieving sorethroat, dispersing the stagnated liver-QI for regulating the stomach.For cough due to lung-heat, sore throat, hoarseness, stomachache due to hyperactive liver-QI attacking the stomach.
Herba Taraxaci: base is former: be feverfew Herba Taraxaci, alkali ground Herba Taraxaci or the dry herb belonging to several plants together.Nature and flavor: bitter, sweet, cold.Gui Jing: return liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Fructus Gardeniae (stir-fry): base is former: be the fruit of Maguireothamnus speciosus Fructus Gardeniae.Get the Fructus Gardeniae of pulverizing, put in pot and fry to golden yellow with slow fire, take out, cool.Nature and flavor: bitter, cold.Gui Jing: enter the heart, liver, lung, stomach warp.Function cures mainly: heat clearing away, pathogenic fire purging, removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.
Rhizoma Bolbostematis: base is former: be the dry tuber of cucurbitaceous plant Rhizoma Bolbostematis.Nature and flavor: bitter, are slightly cold.Gui Jing: return lung, spleen channel.Function cures mainly: eliminating stagnation, detumescence, removing toxic substances.For acute mastitis, scrofula, mastitis, lymphoid tuberculosis, chronic lymphadenitis, hypertrophic rhinitis.
Maifanitum: base is former: Acid-intermediate igneous rock rocks beschtauite.Nature and flavor: sweet; Temperature; Nontoxic.Gui Jing: liver; Stomach; Kidney channel.Function cures mainly: detoxicating and resolving stagnation of pathogens; Removing the necrotic tissue and promoting granulation; Except cold damp eliminating; The liver benefiting stomach invigorating; Blood circulation promoting and blood stasis dispelling; Diuresis fossil; Life lengthening.Main carbuncle carbuncle on the back; Acne; Eczema; Foot gas; Miliaria; Finger is chapped; Chloasma; Toothache; Oral ulcer; Rheumatic arthralgia; Lumbago and backache; Chronic hepatitis; Gastritis; Dysentery; Diabetes; Neurasthenia; Wound is red and swollen; Hypertension; Senile sclerosis of blood vessels; Tumor; Lithangiuria.
Radix Sambuci Chiensis: base is former: be the root of caprifoliaceae plant Herba Sambuci Chiensis.Nature and flavor: sweet in the mouth, acid, property is put down.Function cures mainly: dispel the wind, and dampness removing is invigorated blood circulation, dissipating blood stasis, hemostasis.Main rheumatalgia, wind syndrome of head, lumbago and skelalgia, the moon swollen pouring, card, leucorrhea, traumatic injury, fracture, disease is amassed, spitting of blood, haematemesis, rubella pruritus, and skin ulcer swells.
Herba Scutellariae Barbatae: base is former: be the dry herb of labiate Herba Scutellariae Barbatae.Nature and flavor: pungent, bitter, cold.Gui Jing: return lung, liver, kidney channel.Function cures mainly: heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.
Spica Prunellae: base is former: be the dry fruit ear of labiate Spica Prunellae.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, gallbladder meridian.Function cures mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Concha Ostreae (calcined): base is former: be the shell of the long Concha Ostreae of Ostreidae animal, Dalian Bay Concha Ostreae or Crassostrea rivularis.By the Concha Ostreae cleaned, put on smokeless stove fire and be calcined to canescence, taking-up cools, and pulverizes.Nature and flavor: salty, are slightly cold.Gui Jing: return liver, gallbladder, kidney channel.Function cures mainly: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Fructus Mangifera Indicae core: base is former: be the pit of Anacardiaceae Zhi Wu Fructus Mangifera Indicae.Base is former: sour and astringent, flat.Function cures mainly: control hernia, dyspepsia.
Nodus Nelumbinis Rhizomatis: base is former: be the dry root stipes portion of nymphaeaceae plant lotus.Nature and flavor: sweet, puckery are flat.Gui Jing: return liver, lung, stomach warp.Function cures mainly: hemostasis, repercussive.For spitting blood, spitting of blood, hematuria, metrorrhagia.
test example 1a kind of nasopharyngeal carcinoma of gained of the present invention is regulated the flow of vital energy the clinical practice of detumescence preparation (embodiment 5):
Clinical data: from March ,-2014 in March, 2012, screen 286 routine Nasopharyngeal Carcinoma Patients at 6 hospital outpatients and in-patient department, wherein women 128 example, male 158 example, age 38-72 year, 55.2 ± 3 years old mean age, course of disease 1-3, average course of disease 2.1 ± 0.4 years.Clinical according to Chinese nasopharyngeal carcinoma 2008, I phase 42 example in experimenter, II phase 74 example, III phase 150 example, IV phase 20 example.Diagnostic criteria: 1, Western medicine diagnose standard: with reference to Chinese Anti-Cancer Association's " newly organized common cancer diagnosis and treatment specification " the 4th fascicle (nasopharyngeal carcinoma) diagnostic criteria, and through the pathology person of making a definite diagnosis.2, tcm diagnosis standard: nasal obstruction, tears blood, neck region lump, tinnitus, deafness, headache, pharyngalgia, have a dizzy spell, dry mouth and throat, nausea and vomiting, diplopia, constipation with dry stool, red urine are few, red tongue, tongue are few or nothing, the symptoms such as thready and rapid pulse without strength, conformance with standard more than 5 symptoms can be made a definite diagnosis.
Patient is divided into two groups at random, experimental group and matched group, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, take every day 3 times (warm), each 150m1-200m1(adjusts to some extent depending on concrete condition), 30 days courses for the treatment of, matched group takes other medicine as conventional medication such as Ankangxin capsule, doxifluridine capsule, sky Ganoderma lucidum seu Japonicum capsules.Treatments period carries out Continuous Observation to two groups of patients, and record symptom and change, check before and after all subject, the situation of change of the indexs such as Liver and kidney function, electrocardiogram and stool routine examination.
Curative effect situation criterion: effective: clinical symptoms, sign are obviously improved, rhinopharyngeal neoplasm tumor body reduces, and nascent tumor does not appear in other positions; Effective: clinical symptoms, sign take a turn for the better, rhinopharyngeal neoplasm tumor body has no and increases or reduce, and nascent tumor does not appear in other positions, invalid: clinical symptoms, sign are unchanged, and rhinopharyngeal neoplasm tumor body increases or occurs new focus.
Patient's therapeutic outcome after three months treated by table 1
Through trimestral treatment, two groups of patient treatment outcome are as shown in table 1, therefrom known, effective 63 examples of experimental group, effective 119 examples, total effectively number of cases 182 example of experimental group, total effective rate is 97.9%, and the total effective rate comparing matched group is 78.0%, and the therapeutic effect of visible experimental group is better than matched group.Treatments period, two groups of patients all do not have untoward reaction, and before and after treatment, both patient's Liver and kidney function, electrocardiogram and stool routine examinations etc. are all without comparatively significant change.
Take period patient's self-induction sings and symptoms improvement as shown in table 2.
Table 2 treatments period two groups of patients symptomatic and sign improve situation (improving the front malaise symptoms number of cases of number of cases/treatment)
The present invention has selected the Fructus Xanthii of clearing the nasal passage, the Chinese fanpalm seed of blood circulation promoting and blood stasis dispelling, the Rhizoma Imperatae of clearing away heat and promoting diuresis, the Radix Stephaniae Tetrandrae of inducing diuresis to remove edema, the Semen Oroxyli of dispersing the stagnated liver-QI for regulating the stomach, the Herba Taraxaci of heat-clearing and toxic substances removing, the Fructus Gardeniae of clearing away heat-fire, the Rhizoma Bolbostematis of mass dissipating and swelling eliminating, the Maifanitum of detoxicating and resolving stagnation of pathogens, the Radix Sambuci Chiensis of expelling wind and removing dampness, the Herba Scutellariae Barbatae of blood stasis dispelling diuresis, relieve inflammation or internal heat the Spica Prunellae of improving eyesight, the Concha Ostreae (calcined) of hard masses softening and resolving, the Nodus Nelumbinis Rhizomatis of hemostasis repercussive, multiple medical material is also used, collaborative performance effect, plays the effects such as clearing away heat and promoting diuresis, depressed liver-energy dispersing and QI regulating, mass dissipating and swelling eliminating altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. nasopharyngeal carcinoma is regulated the flow of vital energy a detumescence preparation, it is characterized in that, is prepared from primarily of following bulk drugs, be weight portion: Fructus Xanthii 10-20, Chinese fanpalm seed 9-16, Rhizoma Imperatae 15-20, Radix Stephaniae Tetrandrae 15-20, Semen Oroxyli 6-12, Herba Taraxaci 10-20, Fructus Gardeniae (stir-fry) 8-16, Rhizoma Bolbostematis 10-15, Maifanitum 9-15, Radix Sambuci Chiensis 8-12, Herba Scutellariae Barbatae 6-9, Spica Prunellae 5-12, Concha Ostreae (calcined) 9-15 ， Fructus Mangifera Indicae core 6-10, Nodus Nelumbinis Rhizomatis 15-20.
2. a kind of nasopharyngeal carcinoma as claimed in claim 1 is regulated the flow of vital energy detumescence preparation, it is characterized in that, Fructus Xanthii 12-18, Chinese fanpalm seed 11-14, Rhizoma Imperatae 16-19, Radix Stephaniae Tetrandrae 16-19, Semen Oroxyli 8-10, Herba Taraxaci 12-18, Fructus Gardeniae (stir-fry) 10-14, Rhizoma Bolbostematis 11-14, Maifanitum 11-13, Radix Sambuci Chiensis 9-11, Herba Scutellariae Barbatae 7-8, Spica Prunellae 7-10, Concha Ostreae (calcined) 11-13, Fructus Mangifera Indicae core 7-9, Nodus Nelumbinis Rhizomatis 17-18 is (preferred, Fructus Xanthii 15, Chinese fanpalm seed 12, Rhizoma Imperatae 17.5, Radix Stephaniae Tetrandrae 17.5, Semen Oroxyli 9, Herba Taraxaci 15, Fructus Gardeniae (stir-fry) 12, Rhizoma Bolbostematis 12.5, Maifanitum 12, Radix Sambuci Chiensis 10, Herba Scutellariae Barbatae 7.5, Spica Prunellae 8.5, Concha Ostreae (calcined) 12, Fructus Mangifera Indicae core 8, Nodus Nelumbinis Rhizomatis 17.5).
3. a kind of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2 is regulated the flow of vital energy detumescence preparation, and it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries, pulverize, obtain medicated powder;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) Concha Ostreae (calcined) and Maifanitum are soaked 20 minutes, be heated to boiling, add again pick decontamination Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae, Fructus Mangifera Indicae core and step (2) (3) made crude drug, (preferred, a turn little fire decocts 22-28 minute to turn little fire decoction 20-30 minute; Be more preferably, turn little fire and decoct 25 minutes), filter, obtained filtrate;
(5) step (1) made medicated powder is joined in step (4) made filtrate, stir evenly, obtain decoction.
4. a kind of nasopharyngeal carcinoma as claimed in claim 3 is regulated the flow of vital energy the preparation method of detumescence preparation decoction, it is characterized in that, the 5-8 of step (4) amount of water total raw material medicine quality is doubly (preferred, amount of water is 6-7 times of total raw material medicine quality, be more preferably, amount of water is 6.5 times of total raw material medicine quality).
5. a kind of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2 is regulated the flow of vital energy detumescence preparation, and it is characterized in that, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out, pulverizes together with step (1) (2) made crude drug;
(4) Concha Ostreae (calcined) and Maifanitum are added up the water soaking 20 minutes of crude drug quality 6.5 times, be heated to boiling, add again pick impurity Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae is with Fructus Mangifera Indicae core, (preferred, a turn little fire decocts 22-28 minute to turn little fire decoction 20-30 minute; Be more preferably, turn little fire and decoct 25 minutes), filter, obtained filtrate, filtering residue is for subsequent use;
(5) by step (4) remaining filtering residue, add water and do not have crude drug 3cm, big fire is boiled rear little fire and is decocted, filter, merge with step (4) made filtrate, concentrating under reduced pressure, spraying dry, pulverize after and step (3) made medicated powder mix, add dextrin and starch slurry, soft material processed, granulation wet granular crosses 14 mesh sieves, drying, granulate, obtains granule.
6. a kind of nasopharyngeal carcinoma as claimed in claim 5 is regulated the flow of vital energy the preparation method of detumescence preparation granules agent, it is characterized in that, step (5) big fire is boiled rear little fire and decocted 15-25 minute (preferred, big fire is boiled rear little fire and decocted 17-23 minute; Be more preferably, big fire is boiled rear little fire and is decocted 20 minutes).
7. a kind of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2 is regulated the flow of vital energy detumescence preparation, and it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) by Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae He Fructus Mangifera Indicae core decontamination, cleaning, drying, pulverized 60-80 mesh sieve (preferred together with step (1) (2) (3) made crude drug, pulverized 70 mesh sieves), obtained medicated powder;
(5) by Concha Ostreae (calcined) and Maifanitum removing impurity, put into pot, add the water of both gross masses 7 times, big fire is boiled rear little fire and is decocted, filter, obtain filtrate, step (4) made medicated powder is added in filtrate, stirs evenly, spraying dry, pulverize, by the metering of made dry thing powder according to 0.1-0.3g/ ball (preferred 0.2g/ ball), make pill according to the preparation for processing of pill.
8. a kind of nasopharyngeal carcinoma as claimed in claim 7 is regulated the flow of vital energy the preparation method of detumescence preparation pill, it is characterized in that, step (5) big fire boil rear little fire decoct 30-40 minute (preferred, turn little fire and decoct 32-38 minute; Be more preferably, turn little fire and decoct 35 minutes).
9. a kind of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2 is regulated the flow of vital energy detumescence preparation, and it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Nodus Nelumbinis Rhizomatis to clean up, mix thoroughly with Sucus Zingberis, be then placed in steamer, Steam by water bath 15-20 minute (preferred, Steam by water bath 17 minutes), takes out, dries;
(2) get Chinese fanpalm seed, Rhizoma Imperatae and Fructus Gardeniae (stir-fry) and put into pot, slow fire is made popular, adds Mel and decocting in water to eighty per cant saturating, and vexed 2-4 hour (preferred, vexed 3 hours), exhausts remaining soup, pull out, dry, section;
(3) cleaned by Herba Scutellariae Barbatae, cutting, put into pot, spray saline, slightly vexed, slow fire stir-fries to surface focal spot, takes out;
(4) by Fructus Xanthii, Radix Stephaniae Tetrandrae, Semen Oroxyli, Herba Taraxaci, Rhizoma Bolbostematis, Radix Sambuci Chiensis, Spica Prunellae He Fructus Mangifera Indicae core decontamination, cleaning, drying, pulverize and sieve together with step (1) (2) (3) made crude drug, obtained medicated powder;
(5) by Concha Ostreae (calcined) and Maifanitum removing impurity, put into pot, add the water of both gross masses 7 times, big fire is boiled rear little fire decoction and (preferably, is turned little fire and decoct 32-38 minute for 30-40 minute; Be more preferably, turn little fire and decoct 35 minutes), filter, obtain filtrate, step (4) made medicated powder is added in filtrate, stirs evenly, spraying dry, pulverize, mix with pharmaceutical excipients, soft material processed, make uniform granule, incapsulate, obtain capsule.
10. a kind of nasopharyngeal carcinoma as claimed in claim 9 is regulated the flow of vital energy the preparation method of detumescence preparation capsule, it is characterized in that, step (4) pulverize 100-220 mesh sieve (preferred, pulverized 120-200 mesh sieve; Be more preferably, pulverized 160 mesh sieves).
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