CN104721730A - Compound capsule of stephania sinica diels and fructus livistonae chinensis and preparation method thereof - Google Patents

Compound capsule of stephania sinica diels and fructus livistonae chinensis and preparation method thereof Download PDF

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Publication number
CN104721730A
CN104721730A CN201410700770.7A CN201410700770A CN104721730A CN 104721730 A CN104721730 A CN 104721730A CN 201410700770 A CN201410700770 A CN 201410700770A CN 104721730 A CN104721730 A CN 104721730A
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China
Prior art keywords
parts
clear paste
radix
compound capsule
capsule
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CN201410700770.7A
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Chinese (zh)
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张敬彬
王献
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YOUCARE PHARMACEUTICAL GROUP ANHUI NATURAL PHARMACEUTICAL CO Ltd
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YOUCARE PHARMACEUTICAL GROUP ANHUI NATURAL PHARMACEUTICAL CO Ltd
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Priority to CN201410700770.7A priority Critical patent/CN104721730A/en
Publication of CN104721730A publication Critical patent/CN104721730A/en
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Abstract

The invention relates to a compound capsule of stephania sinica diels and fructus livistonae chinensis and a preparation method thereof. The compound capsule is prepared from the following components: 60 parts of stephania sinica diels, 25 parts of salviae miltiorrhizae, 34 parts of radix bupleuri, 15 parts of zedoary rhizomes, 25 parts of milkvetch roots, 40 parts of gynostemma pentaphyllum, 72 parts of fructus livistonae chinensis and 12 parts of glossy privet fruits. The preparation method of the compound capsule comprises the steps of extracting and decocting. By improving the variety and use amount of the medicinal materials, the function of the compound capsule can be enhanced greatly. The improved compound capsule has the functions of promoting the circulation of blood to remove blood stasis and promoting the circulation of qi to relieve pain, can assist in treating the symptoms of asthma and blood stasis of liver cancer and has good effects of treating and conditioning esophagus cancer and stomach cancer.

Description

A kind of compound capsule with pseudo-ginseng and Chinese fanpalm seed and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of compound capsule with pseudo-ginseng and Chinese fanpalm seed and preparation method thereof.
Background technology
Compound capsule with pseudo-ginseng and Chinese fanpalm seed side separates, and compound capsule with pseudo-ginseng and Chinese fanpalm seed adopts the multiple rare medicinal herbs scientific composition such as Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Chinese fanpalm seed, Radix Bupleuri, Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Herb Gynostemmae Pentaphylli, the Radix Astragali, Fructus Ligustri Lucidi, spirulina clinically, refines and forms.Compound capsule with pseudo-ginseng and Chinese fanpalm seed blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, for Blood stasis hepatocarcinoma auxiliary treatment of panting, the prescription of present use is prescription handed down from ancient times, though there is therapeutical effect, but therapeutic effect is along with the change of the custom of human diet in recent years, and the therapeutic effect of present formula reduces greatly, and first preparation method is not high for the extraction ratio of effective ingredient in medicine.
Summary of the invention
The object of this invention is to provide a kind of compound capsule with pseudo-ginseng and Chinese fanpalm seed formula and its preparation method of improvement, improve the extraction ratio of effective ingredient in effect of medicine and medicine.
The present invention is achieved through the following technical solutions:
A kind of compound capsule with pseudo-ginseng and Chinese fanpalm seed, by weight, is prepared from by following component: Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 60 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Bupleuri 34 parts, Rhizoma Curcumae 15 parts, the Radix Astragali 25 parts, Herb Gynostemmae Pentaphylli 40 parts, Chinese fanpalm seed 72 parts, Fructus Ligustri Lucidi 12 parts.
A preparation method for compound capsule with pseudo-ginseng and Chinese fanpalm seed, comprises the following steps:
(1), by Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Radix Salviae Miltiorrhizae powder be broken into coarse powder, coarse powder added 6 times of weight 70% alcohol reflux 3 times, each 1 hour, merge pure extract, filter, filtrate is concentrated, makes clear paste, clear paste 60 DEG C of relative density 1.10-1.13;
(2), by Radix Bupleuri, Rhizoma Curcumae, the Radix Astragali, Herb Gynostemmae Pentaphylli cutting, Chinese fanpalm seed, Fructus Ligustri Lucidi are smashed to pieces, then with step (1) alcohol extraction after medicinal residues, add 12 times of water gagings, decoct 3 times, each 2 hours, collecting decoction, filter, filtrate is condensed into clear paste, and clear paste 60 DEG C of relative densities are 1.14-1.16;
(3), by the clear paste that step (2) obtains add clear paste weight 1.2-2 ethanol doubly, stir and clear paste is dissolved, leave standstill 12h, filter, filtrate is condensed into clear paste, and clear paste 60 DEG C of relative densities are 1.08-1.12;
(4), by clear paste obtained with step (3) for clear paste obtained for step (1) mix, vacuum drying, pulverize, sieve, add adjuvant, make capsule.
Beneficial effect of the present invention: capsule with pseudo-ginseng and Chinese fanpalm seed provided by the invention is by improving the kind of medicine and consumption, substantially increase the function of golden Pu capsule, capsule with pseudo-ginseng and Chinese fanpalm seed after improvement not only blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, for Blood stasis hepatocarcinoma auxiliary treatment of panting, and for esophageal carcinoma, gastric cancer also has well treatment and conditioning effect, medicine of the present invention does not need to use spirulina, reduce the cost of medicine, by the component content of regulating drug, improve drug effect, through realizing measuring, capsule with pseudo-ginseng and Chinese fanpalm seed prepared by the present invention also has good therapeutic effect through test determination for gastric cancer.
Detailed description of the invention
A kind of compound capsule with pseudo-ginseng and Chinese fanpalm seed, by weight, is prepared from by following component: Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 60 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Bupleuri 34 parts, Rhizoma Curcumae 15 parts, the Radix Astragali 25 parts, Herb Gynostemmae Pentaphylli 40 parts, Chinese fanpalm seed 72 parts, Fructus Ligustri Lucidi 12 parts.
A preparation method for compound capsule with pseudo-ginseng and Chinese fanpalm seed, comprises the following steps:
(1), by Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Radix Salviae Miltiorrhizae powder be broken into coarse powder, coarse powder added 6 times of weight 70% alcohol reflux 3 times, each 1 hour, merge pure extract, filter, filtrate is concentrated, makes clear paste, clear paste 60 DEG C of relative density 1.10-1.13;
(2), by Radix Bupleuri, Rhizoma Curcumae, the Radix Astragali, Herb Gynostemmae Pentaphylli cutting, Chinese fanpalm seed, Fructus Ligustri Lucidi are smashed to pieces, then with step (1) alcohol extraction after medicinal residues, add 12 times of water gagings, decoct 3 times, each 2 hours, collecting decoction, filter, filtrate is condensed into clear paste, and clear paste 60 DEG C of relative densities are 1.14-1.16;
(3), by the clear paste that step (2) obtains add clear paste weight 1.2-2 ethanol doubly, stir and clear paste is dissolved, leave standstill 12h, filter, filtrate is condensed into clear paste, and clear paste 60 DEG C of relative densities are 1.08-1.12;
(4), by clear paste obtained with step (3) for clear paste obtained for step (1) mix, vacuum drying, pulverize, sieve, add adjuvant, make capsule.
Said method and raw material is used to can be made into 420 capsule with pseudo-ginseng and Chinese fanpalm seed.
After testing, the capsule with pseudo-ginseng and Chinese fanpalm seed every that prepared by the present invention is no less than 55 μ g containing tanshinone IIA.Substantially increase utilization rate and the drug effect of raw material.

Claims (2)

1. a compound capsule with pseudo-ginseng and Chinese fanpalm seed, is characterized in that, by weight, is prepared from by following component: Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 60 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Bupleuri 34 parts, Rhizoma Curcumae 15 parts, the Radix Astragali 25 parts, Herb Gynostemmae Pentaphylli 40 parts, Chinese fanpalm seed 72 parts, Fructus Ligustri Lucidi 12 parts.
2. a preparation method for compound capsule with pseudo-ginseng and Chinese fanpalm seed according to claim 1, is characterized in that, comprises the following steps:
(1), by Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Radix Salviae Miltiorrhizae powder be broken into coarse powder, coarse powder added 6 times of weight 70% alcohol reflux 3 times, each 1 hour, merge pure extract, filter, filtrate is concentrated, makes clear paste, clear paste 60 DEG C of relative density 1.10-1.13;
(2), by Radix Bupleuri, Rhizoma Curcumae, the Radix Astragali, Herb Gynostemmae Pentaphylli cutting, Chinese fanpalm seed, Fructus Ligustri Lucidi are smashed to pieces, then with step (1) alcohol extraction after medicinal residues, add 12 times of water gagings, decoct 3 times, each 2 hours, collecting decoction, filter, filtrate is condensed into clear paste, and clear paste 60 DEG C of relative densities are 1.14-1.16;
(3), by the clear paste that step (2) obtains add clear paste weight 1.2-2 ethanol doubly, stir and clear paste is dissolved, leave standstill 12h, filter, filtrate is condensed into clear paste, and clear paste 60 DEG C of relative densities are 1.08-1.12;
(4), by clear paste obtained with step (3) for clear paste obtained for step (1) mix, vacuum drying, pulverize, sieve, add adjuvant, make capsule.
CN201410700770.7A 2014-11-28 2014-11-28 Compound capsule of stephania sinica diels and fructus livistonae chinensis and preparation method thereof Pending CN104721730A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112843206A (en) * 2021-03-24 2021-05-28 郑州大学 Medicine for treating tumor and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1879849A (en) * 2006-05-06 2006-12-20 安徽科创中药天然药物研究所有限责任公司 Compound capsule with pseudo-ginseng and Chinese fanpalm seed, its preparation process and quality control method
CN101693096A (en) * 2009-10-22 2010-04-14 广西医科大学附属肿瘤医院 Medicament for treating liver cancer and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1879849A (en) * 2006-05-06 2006-12-20 安徽科创中药天然药物研究所有限责任公司 Compound capsule with pseudo-ginseng and Chinese fanpalm seed, its preparation process and quality control method
CN101693096A (en) * 2009-10-22 2010-04-14 广西医科大学附属肿瘤医院 Medicament for treating liver cancer and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
刘玉芹: "《中医护理学》", 31 January 2014 *
吴英德 等: "复方金蒲片临床研究概述", 《广西医学》 *
梁安鹏 等: "《药物集成.3,中成药.1》", 30 June 2008 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112843206A (en) * 2021-03-24 2021-05-28 郑州大学 Medicine for treating tumor and preparation method thereof

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Application publication date: 20150624