CN104721470A - Externally-used liniment for treating flat warts - Google Patents
Externally-used liniment for treating flat warts Download PDFInfo
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- CN104721470A CN104721470A CN201510136772.2A CN201510136772A CN104721470A CN 104721470 A CN104721470 A CN 104721470A CN 201510136772 A CN201510136772 A CN 201510136772A CN 104721470 A CN104721470 A CN 104721470A
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Abstract
The invention discloses an externally-used liniment for treating flat warts. The externally-used liniment for treating flat warts is characterized by being prepared from nutgrass galingale rhizomes, airpotato yam rhizomes, largehead atractylodes rhizomes, black nightshade herb, common scouring rush herb, safflowers, white wine and dimethyl sulfoxide. The externally-used liniment for treating flat warts is simple and convenient to use and has the advantages of novel formula, simplicity in preparation and definite treatment effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine, relate to a kind of externally applied liniment for the treatment of verruca plana or rather.
Background technology
Verruca plana is infected by human papillomavirus (HPV) and causes, and is apt to occur in teen-age disease of viral infection.Clinical manifestation is color of the leather or peach flat pimple, is more common in face and the back of the hand, without obvious subjective symptoms, by direct or indirect contagion.Pathologic finding epidermis basket shape hyperkeratosis companion parakeratosis, acanthosis, the visible more physaliphore in epidermis top, karyon basophilic, granular layer is evenly plump, and corium changes not obvious.
Verruca plana is referred to as in Chinese medicine " verruca plana ", and the traditional Chinese medical science is thought, because the heresy of pathogenic wind toxic is met, to fight in skin, hinders caused by the lung meridian.Because wind is arrogant greatly, long-pending Yu Huare, qi stagnation hemagglutination, or interior dynamic liver-wind, therefore wart tires out solid difficulty goes.
Current doctor trained in Western medicine often adopts the means such as oral enhancing immune drug, external antiviral drugs, galvanocautery physiotherapy, liquid nitrogen cold therapy, autologous heeling-in and laser therapy to carry out Comprehensive Treatment primary disease.But clinical practice proves that these methods do not have basic therapeutical effect, easily recurs, and prolonged and repeated medication easily occurs poisonous side effect of medicine, feelings of causing a disease transform.
Therefore, invent a kind of externally applied liniment evident in efficacy for treatment verruca plana, what just seem is very necessary.
Summary of the invention
The object of this invention is to provide a kind of externally applied liniment for the treatment of verruca plana, there is the advantages such as novel formula, preparation are simple, determined curative effect.
A kind of externally applied liniment for the treatment of verruca plana, the raw material composition of its effective ingredient and weight thereof are: Rhizoma Cyperi 30-70 gram, Rhizoma Dioscoreae Bulbiferae 10-40 gram, Rhizoma Atractylodis 60-150 gram, Herba Solani Nigri 10-40 gram, Herba Equiseti Hiemalis 30-70 gram, Flos Carthami 10-30 gram, 60 degree of Chinese liquor 200-600 milliliters, dimethyl sulfoxide 100-400 milliliters.
The preferred version of externally applied liniment of the present invention, be make this externally applied liniment effective ingredient raw material composition and weight be: Rhizoma Cyperi 50 grams, Rhizoma Dioscoreae Bulbiferae 25 grams, Rhizoma Atractylodis 100 grams, Herba Solani Nigri 25 grams, Herba Equiseti Hiemalis 50 grams, 20 grams, Flos Carthami, 60 degree of Chinese liquor 400 milliliters, dimethyl sulfoxide 300 milliliters.
The pharmacological property of externally applied liniment main component of the present invention is as follows.
Rhizoma Cyperi: be the dry rhizome of sedge dried tuber;
Nature and flavor: pungent, micro-hardship, micro-sweet are flat;
Gui Jing: return liver, spleen, tri-jiao channel;
Effect: dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving.
Rhizoma Dioscoreae Bulbiferae: be the dry tuber of Dioscoreaceae yam Dioscorea bulbifera L.;
Nature and flavor: bitter in the mouth, pungent, cool in nature;
Gui Jing: return liver, stomach, the heart, lung meridian;
Effect: removing toxic substances and promoting subsidence of swelling, dissipating phlegm and resolving masses, cooling blood for hemostasis.
Rhizoma Atractylodis: be the dry rhizome of feverfew Atractylodes lancea (Thunb.) DC.;
Nature and flavor: acrid in the mouth, hardship, warm in nature;
Gui Jing: return spleen, stomach, Liver Channel;
Effect: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.
Herba Solani Nigri: Herb is used as medicine;
Nature and flavor: cold in nature, bitter in the mouth, micro-sweet, there is mild toxicity;
Gui Jing: return lung, stomach, urinary bladder channel;
Effect: heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema, eliminating phlegm and stopping cough.
Herba Equiseti Hiemalis: be the dry aerial parts of Equisetaceae plant Herba Equiseti Hiemalis;
Nature and flavor: sweet; Bitter; Flat; Nontoxic; Be slightly cold;
Gui Jing: heart channel; Liver Channel; Stomach warp; Urinary bladder channel;
Effect: liver heat removing and eyesight improving; Hemostasis; Inducing diuresis for treating stranguria syndrome.
Flos Carthami: be the dried floral of feverfew Flos Carthami;
Nature and flavor: acrid in the mouth, warm in nature;
Gui Jing: GUIXIN, Liver Channel;
Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
Dimethyl sulfoxide: be a kind of not only water-soluble but also be dissolved in the very important aprotic polar solvent of organic solvent.Be widely used as solvent and reaction reagent, there is very high selection extracting ability.Dimethyl sulfoxide has anti-inflammatory analgetic, diuresis, calm grade for effect itself, directly can be used as raw material and the carrier of some drugs in medical industry.Have the title of " catholicon ", the active component of Chang Zuowei analgesic drug product makes an addition among medicine.
Treat an externally applied liniment for verruca plana, its Therapeutic Principle is invigorating the spleen to clear away damp pathogen, promoting blood circulation to restore menstrual flow, removing toxic substances and promoting subsidence of swelling.Composition of raw materials being followed the property of medicine through belonging to, laying particular stress on invigorating the spleen to clear away damp pathogen, taking into account whole machine balancing, regulating menstruation removing toxic substances and promoting subsidence of swelling of stopping over.In medicine, Rhizoma Atractylodis have effect that is drying damp and strengthening spleen, expelling wind and cold; Rhizoma Cyperi, Flos Carthami have regulating menstruation, dissipating blood stasis, analgesic effect; Rhizoma Dioscoreae Bulbiferae, Herba Equiseti Hiemalis, Herba Solani Nigri have clearing heat, releasing toxin, removing swelling, removing heat from blood and promoting blood circulation effect; Chinese liquor has by blood vessels, resisting cold gas, the effect of row medicine gesture; Dimethyl sulfoxide has anti-inflammatory analgetic, diuresis, calm grade for effect itself.Said components, through dialectical compatibility, complements each other using, and medicine is directly invested focus, thus effectively given play to effect of invigorating the spleen to clear away damp pathogen, promoting blood circulation to restore menstrual flow, removing toxic substances and promoting subsidence of swelling, to reach the object of curing verruca plana.
Present invention also offers a kind of preparation method for the treatment of the externally applied liniment of verruca plana:
After Rhizoma Cyperi, Rhizoma Dioscoreae Bulbiferae, Rhizoma Atractylodis are ground into coarse granule, put into 60 degree of Chinese liquor and soak 15 days together with Herba Solani Nigri, Herba Equiseti Hiemalis, Flos Carthami, cross leaching supernatant.Every 100 milliliters of supernatant add 30 milliliters of dimethyl sulfoxide and namely obtain externally applied liniment of the present invention.
Using method:
During treatment verruca plana, directly liniment of the present invention is applied on wart body with cotton swab, repeatedly smears 4-8 time, every day 2 times.
In order to make object of the present invention, technical scheme and advantage clearly understand below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
Embodiment 1:
Rhizoma Cyperi 70 grams, Rhizoma Dioscoreae Bulbiferae 40 grams, Rhizoma Atractylodis 150 grams, Herba Solani Nigri 40 grams, Herba Equiseti Hiemalis 70 grams, 30 grams, Flos Carthami, 60 degree of Chinese liquor 600 milliliters, dimethyl sulfoxide 400 milliliters.
Embodiment 2:
Rhizoma Cyperi 60 grams, Rhizoma Dioscoreae Bulbiferae 30 grams, Rhizoma Atractylodis 120 grams, Herba Solani Nigri 30 grams, Herba Equiseti Hiemalis 35 grams, 25 grams, Flos Carthami, 60 degree of Chinese liquor 500 milliliters, dimethyl sulfoxide 400 milliliters.
Embodiment 3:
Rhizoma Cyperi 50 grams, Rhizoma Dioscoreae Bulbiferae 25 grams, Rhizoma Atractylodis 100 grams, Herba Solani Nigri 25 grams, Herba Equiseti Hiemalis 50 grams, 20 grams, Flos Carthami, 60 degree of Chinese liquor 400 milliliters, dimethyl sulfoxide 300 milliliters.
Embodiment 4:
Rhizoma Cyperi 30 grams, Rhizoma Dioscoreae Bulbiferae 10 grams, Rhizoma Atractylodis 60 grams, Herba Solani Nigri 10 grams, Herba Equiseti Hiemalis 30 grams, 10 grams, Flos Carthami, 60 degree of Chinese liquor 200 milliliters, dimethyl sulfoxide 100 milliliters.
Below by clinical experiment, curative effect of the present invention is verified.
Clinical data
1.1 case selection
It is head of the horse town, in January, 2010 Linyi City in March ,-2012 Tancheng County hospital outpatient verruca plana patient that 32 examples observe case, meet " Yang Guoliang dermatological " (Wang Xiasheng, Liao Kanghuang. Yang Guoliang dermatological [M]. Shanghai: Shanghai scientific and technical literature publishing house, 2005.309.) relevant verruca plana diagnostic criteria.Wherein man 18 example, female 14 example, at 14 ~ 38 years old age, 22 years old mean age, the course of disease is the shortest 1 month, the longest 1 year half; Skin lesion site of pathological change greatly mainly with face, cervical region is main, small number of patients occurs in hand, shirtfront; All without other antiviral and immune modulating treatment in 2 months.
1.2 Therapeutic Method
Give verruca plana patient externally applied liniment of the present invention, directly liniment of the present invention is applied on wart body with cotton swab, repeatedly smears 4-8 time, every day 2 times, continuous wiping 2 weeks.
1.3 criterion of therapeutical effect
According to " Chinese medical disease Standardization of diagnosis and curative effect " (State Administration of Traditional Chinese Medicine. Chinese medical disease Standardization of diagnosis and curative effect [S]. Nanjing: publishing house of Nanjing University, 1994.145.) draft.
Recovery from illness: wart body all disappears and occurs without new skin lesion;
Effective: wart body disappears more than 70%;
Take a turn for the better: wart body disappears 30% ~ 70%;
Invalid: wart body disappears and is less than 30% or without significant change.
Effective percentage is cure rate, obvious effective rate, improvement rate sum.
1.4 therapeutic outcome
32 routine patients fully recover 24 examples (75.00%), and effective 5 examples (15.63%), 2 examples that take a turn for the better (6.25%), invalid 1 example (3.13%), effective percentage is 96.88%.Untoward reaction is there is without 1 routine patient in therapeutic process.
Claims (2)
1. treat the externally applied liniment of verruca plana for one kind, it is characterized in that, the raw material composition of effective ingredient and weight thereof are: Rhizoma Cyperi 30-70 gram, Rhizoma Dioscoreae Bulbiferae 10-40 gram, Rhizoma Atractylodis 60-150 gram, Herba Solani Nigri 10-40 gram, Herba Equiseti Hiemalis 30-70 gram, Flos Carthami 10-30 gram, 60 degree of Chinese liquor 200-600 milliliters, dimethyl sulfoxide 100-400 milliliters.
2. a kind of externally applied liniment for the treatment of verruca plana according to claim 1, it is characterized in that, the raw material composition of effective ingredient and weight thereof are: Rhizoma Cyperi 50 grams, Rhizoma Dioscoreae Bulbiferae 25 grams, Rhizoma Atractylodis 100 grams, Herba Solani Nigri 25 grams, Herba Equiseti Hiemalis 50 grams, 20 grams, Flos Carthami, 60 degree of Chinese liquor 400 milliliters, dimethyl sulfoxide 300 milliliters.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510136772.2A CN104721470A (en) | 2015-03-27 | 2015-03-27 | Externally-used liniment for treating flat warts |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510136772.2A CN104721470A (en) | 2015-03-27 | 2015-03-27 | Externally-used liniment for treating flat warts |
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| CN104721470A true CN104721470A (en) | 2015-06-24 |
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| CN201510136772.2A Pending CN104721470A (en) | 2015-03-27 | 2015-03-27 | Externally-used liniment for treating flat warts |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1762473A (en) * | 2004-10-21 | 2006-04-26 | 马学荣 | Traditional Chinese medicine for treating flat wart |
| EP2520303A1 (en) * | 2011-05-04 | 2012-11-07 | G & E Herbal Biotechnology Co., Ltd. | Anti-wart pharmaceutical composition |
-
2015
- 2015-03-27 CN CN201510136772.2A patent/CN104721470A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1762473A (en) * | 2004-10-21 | 2006-04-26 | 马学荣 | Traditional Chinese medicine for treating flat wart |
| EP2520303A1 (en) * | 2011-05-04 | 2012-11-07 | G & E Herbal Biotechnology Co., Ltd. | Anti-wart pharmaceutical composition |
Non-Patent Citations (2)
| Title |
|---|
| 王元松等: "《皮肤科金方》", 31 July 2001, 河北科学技术出版社 * |
| 程延安等: "《中医杂病证治》", 30 June 1994, 中原农民出版社 * |
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Application publication date: 20150624 |