CN105920588A - Xianhuang foot healing ointment and preparation method thereof - Google Patents

Xianhuang foot healing ointment and preparation method thereof Download PDF

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Publication number
CN105920588A
CN105920588A CN201610415157.XA CN201610415157A CN105920588A CN 105920588 A CN105920588 A CN 105920588A CN 201610415157 A CN201610415157 A CN 201610415157A CN 105920588 A CN105920588 A CN 105920588A
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parts
foot
healing
insulin
cortex phellodendri
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黄博婷
周纯燕
蚁楷宏
许桂华
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First Affiliated Hospital of Shantou University Medical College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
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  • Gastroenterology & Hepatology (AREA)
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Abstract

The invention relates to Xianhuang foot healing ointment and a preparation method thereof. The Xianhuang foot healing ointment comprises, by weight, 12-18 parts of semen hygrophilae salicifoliae, 18-20 parts of astragalus, 12-18 parts of golden cypress, 8-12 parts of red peony, 8-12 parts of common bletilla tuber, 30-60 parts of sesame oil and 3-5 parts of insulin. According to the Xianhuang foot healing ointment, the golden cypress, the red peony and the common bletilla tuber serve as basic elements for treating the open part of a sore, the open part of the sore is subjected to heat clearing, blood cooling, antibiosis, detumescence, stasis removal, pain relieving, healing, tissue regeneration and the like. The semen hygrophilae directly acts on an ulcer surface to perform detumescence, relieve pain, improve local microcirculation and promote sore granulation and ulcer healing, the healing time of diabetic foot ulcers is shortened under the coordination of the golden cypress and the insulin, the components co-act, so that qi benefiting, blood activating, blood stasis dissipating, heat clearing, detoxification, dental caries removal, detumescence, tissue regeneration and pain reliving are realized, healing of the open part of the diabetic foot sore is promoted, treatment effects are better, treatment cycle is substantially shortened, and the pain of a patient is relieved.

Description

A kind of celestial yellow foot more cream and preparation method thereof
Technical field
The present invention relates to a kind of external-applied ointment, particularly relate to a kind of celestial yellow foot more cream and preparation method thereof.
Background technology
Diabetic foot is one of common complication of diabetes, is to cause due to diabetic peripheral neuropathy and the various pathological changes of peripheral vessel in various degree lower limb to infect, lose sick, deep tissue and destroy.
Diabetic foot belongs to Chinese medicine necrosis category, and for the disease of deficiency in origin and excess in superficiality, main pathogenesis mostly is blood stasis due to qi deficiency, damp and hot poison, so that stasis blocking venation, contaminates into skin ulcer.There is red and swollen heat pain in diabetic foot local, likes that cool To Be Protected from Heat, and Chinese medical discrimination belongs to " hot stasis of blood disease ", and the treatment of diabetic foot more preferably uses the methods such as benefiting QI for activating blood circulation, clearing heat and expelling damp, eliminating blood stasis and smoothing collaterals, detumescence and promoting granulation.The traditional Chinese medical science thinks that disease is sent out in four ends, and medicine is difficult to arrive, therefore the effect of general endo-medicine or garter is the most poor, it is difficult to healing, and therefore, the more difficult recovery from illness at present of glycosuria pedopathy, treatment cycle is longer, and this is the difficult problem that our medical circle is endeavoured to solve always.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of celestial yellow foot more cream and preparation method thereof, and this celestial yellow foot more cream can promote diabetic foot wound healing, and therapeutic effect is more preferable, and treatment cycle is greatly shortened, and reduces patient suffering.The technical scheme used is as follows:
A kind of celestial yellow foot more cream, it is characterised in that each component of described celestial yellow foot more cream is respectively as follows: seed of Hygrophila saxatilis Ridl. 12~18 parts, the Radix Astragali 18~20 parts, Cortex Phellodendri 12~18 parts, Radix Paeoniae Rubra 8~12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8~12 parts, Oleum Sesami 30~60 parts, Insulin 3~5 parts by weight.
Seed of Hygrophila saxatilis Ridl. is the seed of acanthaceous plant Flos Caryophylli Hygrophila salicifolia, have heat clearing away, spasmolytic, pain relieving, subside a swelling, draw out the pus, draw out pus by applying a plaster to the affected part, the effect such as granulation promoting, it is used for treating furuncle, toxic swelling outside often, the mucous modification epidermis cell hair utilizing its surface of the seed among the people meets the feature of hygral expansion adhesion in bulk, for external application furuncle, inhales pus.Modern Study of Medicinal Herbs result confirms: seed of Hygrophila saxatilis Ridl. does not only has detumescence, analgesic effect, and has and improve local microcirculation effect.Utilize above effect of seed of Hygrophila saxatilis Ridl., during external application, can be done directly on ulcer surface, promote ulcer healing, do not find untoward reaction in using, and achieve positive effect.
Modern medicine study shows, the Radix Astragali have toxin expelling evacuation of pus, promoting regeneration of the tissue and arresting bleeding, enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and wide antibacterial action.Can eliminate Jishengshenqiwan albuminuria, strengthen myocardial contraction, regulate blood sugar content, the Radix Astragali can not only coronary artery dilator, improve blood circulation, improve immunologic function, and downright bad histiocyte can be made to rejuvenate.Clinically, the Radix Astragali can be used to treat diabetes, have QI invigorating consolidate, the effect of blood sugar lowering of promoting blood circulation.
Cortex Phellodendri property Huang bitter in the mouth, there is heat clearing and damp drying pathogenic fire purging, except effect of steaming detoxification sore treatment, the antibiotic effective ingredient of Cortex Phellodendri is little alkali, has broad-spectrum antibacterial action, staphylococcus aureus, escherichia coli, bacillus pyocyaneus had stronger inhibitory action, the most inhibited, additionally, the most also find that HUANGBAI(sic) can eliminate tissue edema to bacillus subtilis, bordetella pertussis, clostridium tetani, promote angiogenesis, improve the effects such as local microcirculation.
Radix Paeoniae Rubra bitter in the mouth cold nature, has effect of heat clearing away, removing heat from blood, detumescence, blood stasis dispelling, pain relieving, is good at promoting blood circulation to remove blood stasis, is the good medicine of the diseases such as stagnation of QI-blood such as treatment sore and toxic.Additionally, modern pharmacological research shows, Radix Paeoniae Rubra total glycosides in body inside and outside all have significantly anti-in toxic action, and escherichia coli, the type strain of Pseudomonas aeruginosa and clinical strain are had better inhibition effect.
Pseudobulbus Bletillae (Rhizoma Bletillae) bitter in the mouth, sweet, puckery, cold nature, can detumescence and promoting granulation, sore, quality sticks greasy simultaneously, and skin and mucosa are had maintenance effect.
Oleum Sesami then plays refrigerant, moisturizing, antibacterial effect.
In sum, this celestial yellow foot more cream is with Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae) is as the fundamental of the treatment open sore part, the open sore part is carried out heat clearing away, removing heat from blood, antibacterial, detumescence, blood stasis dispelling, pain relieving, sore, granulation promoting etc., additionally, due to adding the Pseudobulbus Bletillae (Rhizoma Bletillae), it is partially formed a protecting film in the open sore part, effectively control and prevent from infecting, shorten blood clotting time, reduce hemorrhage, thus the healing of beneficially wound surface, ulcer surface is directly acted on again by seed of Hygrophila saxatilis Ridl., subside a swelling, pain relieving, improve local microcirculation, promote the growth of open sore part granulation, promote ulcer healing, again under the cooperation of Cortex Phellodendri and insulin, promote the healing time of diabetic foot ulcers, reduce amputation rate.In formula, seed of Hygrophila saxatilis Ridl., the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae), insulin cooperate, and jointly act on, thus benefiting QI for activating blood circulation dissipating blood stasis, heat-clearing and toxic substances removing putrefaction removing, detumescence and promoting granulation pain relieving, promoting diabetic foot wound healing, therapeutic effect is more preferable, treatment cycle is greatly shortened, reduces patient suffering.
The preparation method of a kind of celestial yellow foot more cream, it is characterised in that comprise the steps:
(1), the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae) are weighed in proportion, and grind into powder, be then immersed in Oleum Sesami 4~6 days;
(2), with slow fire, the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae), the mixture of Oleum Sesami are boiled to the most bitter;
(3), excessively medicinal residues fragment thicker in described mixture is filtered off;
(4) the described mixture boiled after, filtering;
(5), by described mixture stand and be cooled to 35~40 DEG C, be subsequently adding seed of Hygrophila saxatilis Ridl. powder, be stirred into paste;
(6), take out appropriate described paste, be proportionally added into insulin and stir, form a patch celestial yellow foot more cream.
As the preferred version of the present invention, described seed of Hygrophila saxatilis Ridl., the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae), Oleum Sesami, insulin are respectively as follows: seed of Hygrophila saxatilis Ridl. 12~18 parts, the Radix Astragali 18~20 parts, Cortex Phellodendri 12~18 parts, Radix Paeoniae Rubra 8~12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8~12 parts, Oleum Sesami 30~60 parts, Insulin 3~5 parts by weight.
The present invention compared with prior art, has the advantage that
This celestial yellow foot more cream is with Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae) is as the fundamental of the treatment open sore part, the open sore part is carried out heat clearing away, removing heat from blood, antibacterial, detumescence, blood stasis dispelling, pain relieving, sore, granulation promoting etc., additionally, due to adding the Pseudobulbus Bletillae (Rhizoma Bletillae), it is partially formed a protecting film in the open sore part, effectively control and prevent from infecting, shorten blood clotting time, reduce hemorrhage, thus the healing of beneficially wound surface, ulcer surface is directly acted on again by seed of Hygrophila saxatilis Ridl., subside a swelling, pain relieving, improve local microcirculation, promote the growth of open sore part granulation, promote ulcer healing, again under the cooperation of Cortex Phellodendri and insulin, promote the healing time of diabetic foot ulcers, reduce amputation rate.In formula, seed of Hygrophila saxatilis Ridl., the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae), insulin cooperate, and jointly act on, thus benefiting QI for activating blood circulation dissipating blood stasis, heat-clearing and toxic substances removing putrefaction removing, detumescence and promoting granulation pain relieving, promoting diabetic foot wound healing, therapeutic effect is more preferable, treatment cycle is greatly shortened, reduces patient suffering.
Detailed description of the invention
Below the preferred embodiment of the present invention is described further.
Embodiment one
This celestial yellow foot more cream, each component is respectively as follows: seed of Hygrophila saxatilis Ridl. 12 parts, the Radix Astragali 20 parts, Cortex Phellodendri 18 parts, Radix Paeoniae Rubra 12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, 60 parts of Oleum Sesami, insulin 5 parts by weight.
The preparation method of this celestial yellow foot more cream, comprises the steps:
(1), the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae) are weighed in proportion, and grind into powder, be then immersed in Oleum Sesami 5 days (4~6 days can);
(2), with slow fire, the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae), the mixture of Oleum Sesami are boiled to the most bitter;
(3), excessively medicinal residues fragment thicker in described mixture is filtered off;
(4) the described mixture boiled after, filtering;
(5), by described mixture stand and be cooled to 37 DEG C (35~40 DEG C can), be subsequently adding seed of Hygrophila saxatilis Ridl. powder, be stirred into paste;
(6), take out appropriate described paste, be proportionally added into insulin and stir, form a patch celestial yellow foot more cream.
Embodiment two
In the case of other parts are all identical with embodiment one, its content differing only in each component differs, in the present embodiment, each component is respectively as follows: seed of Hygrophila saxatilis Ridl. 12 parts, the Radix Astragali 18 parts, Cortex Phellodendri 12 parts, Radix Paeoniae Rubra 8 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8 parts, 30 parts of Oleum Sesami, Insulin 3 part by weight.
Embodiment three
In the case of other parts are all identical with embodiment one, its content differing only in each component differs, in the present embodiment, each component is respectively as follows: each component by weight and is respectively as follows: seed of Hygrophila saxatilis Ridl. 15 parts, the Radix Astragali 15 parts, Cortex Phellodendri 15 parts, Radix Paeoniae Rubra 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, 50 parts of Oleum Sesami, insulin 4 parts by weight.
Embodiment four
In the case of other parts are all identical with embodiment one, its content differing only in each component differs, in the present embodiment, each component is respectively as follows: seed of Hygrophila saxatilis Ridl. 12 parts, the Radix Astragali 20 parts, Cortex Phellodendri 12 parts, Radix Paeoniae Rubra 11 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, 40 parts of Oleum Sesami, Insulin 3 part by weight.
In addition; it should be noted that the specific embodiment described in this specification, its each several part title etc. can be different; all equivalences done according to structure, feature and the principle described in inventional idea of the present invention or simple change, be all included in the protection domain of patent of the present invention.Described specific embodiment can be made various amendment or supplements or use similar mode to substitute by those skilled in the art; without departing from the structure of the present invention or surmount scope defined in the claims, protection scope of the present invention all should be belonged to.

Claims (3)

1. a celestial yellow foot more cream, it is characterised in that each component of described celestial yellow foot more cream is respectively as follows: seed of Hygrophila saxatilis Ridl. 12~18 parts, the Radix Astragali 18~20 parts, Cortex Phellodendri 12~18 parts, Radix Paeoniae Rubra 8~12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8~12 parts, Oleum Sesami 30~60 parts, Insulin 3~5 parts by weight.
2. the preparation method of a celestial yellow foot more cream, it is characterised in that comprise the steps:
(1), the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae) are weighed in proportion, and grind into powder, be then immersed in Oleum Sesami 4~6 days;
(2), with slow fire, the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae), the mixture of Oleum Sesami are boiled to the most bitter;
(3), excessively medicinal residues fragment thicker in described mixture is filtered off;
(4) the described mixture boiled after, filtering;
(5), by described mixture stand and be cooled to 35~40 DEG C, be subsequently adding seed of Hygrophila saxatilis Ridl. powder, be stirred into paste;
(6), take out appropriate described paste, be proportionally added into insulin and stir, form a patch celestial yellow foot more cream.
3. the preparation method of celestial yellow foot more cream as claimed in claim 2, it is characterised in that: described seed of Hygrophila saxatilis Ridl., the Radix Astragali, Cortex Phellodendri, Radix Paeoniae Rubra, the Pseudobulbus Bletillae (Rhizoma Bletillae), Oleum Sesami, insulin are respectively as follows: seed of Hygrophila saxatilis Ridl. 12~18 parts, the Radix Astragali 18~20 parts, Cortex Phellodendri 12~18 parts, Radix Paeoniae Rubra 8~12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8~12 parts, Oleum Sesami 30~60 parts, Insulin 3~5 parts by weight.
CN201610415157.XA 2016-06-15 2016-06-15 Xianhuang foot healing ointment and preparation method thereof Pending CN105920588A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107951945A (en) * 2017-11-14 2018-04-24 汕头大学医学院第附属医院 External application Chinese medicine gel dressing and preparation method thereof
CN110585421A (en) * 2019-09-29 2019-12-20 邱彦龙 External composition for treating diabetic foot disease and preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645230A (en) * 2015-02-04 2015-05-27 郭敏 Traditional Chinese medicine for assisting in treating diabetic foot and preparation method of foot soaking solution

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN104645230A (en) * 2015-02-04 2015-05-27 郭敏 Traditional Chinese medicine for assisting in treating diabetic foot and preparation method of foot soaking solution

Non-Patent Citations (3)

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曾小芳等: "南天仙子外敷与皮维碘外敷治疗压疮的疗效比较", 《中国临床研究》 *
王伟志等: "糖尿病足应用胰岛素外敷治疗的效果分析", 《中国卫生标准管理》 *
田舸: "《中药学专业知识(一)》", 28 February 2009, 中国中医药出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107951945A (en) * 2017-11-14 2018-04-24 汕头大学医学院第附属医院 External application Chinese medicine gel dressing and preparation method thereof
CN110585421A (en) * 2019-09-29 2019-12-20 邱彦龙 External composition for treating diabetic foot disease and preparation method and application thereof

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Inventor after: Zheng Yinfang

Inventor after: Zhou Chunyan

Inventor after: Huang Zehong

Inventor after: Xu Guihua

Inventor before: Huang Boting

Inventor before: Zhou Chunyan

Inventor before: Yi Kaihong

Inventor before: Xu Guihua

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Application publication date: 20160907