CN102688368B - Traditional Chinese medicine for treating trauma hemostasis or telephium - Google Patents

Traditional Chinese medicine for treating trauma hemostasis or telephium Download PDF

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CN102688368B
CN102688368B CN2011103896915A CN201110389691A CN102688368B CN 102688368 B CN102688368 B CN 102688368B CN 2011103896915 A CN2011103896915 A CN 2011103896915A CN 201110389691 A CN201110389691 A CN 201110389691A CN 102688368 B CN102688368 B CN 102688368B
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乔琦
耿继红
胡庆九
耿源
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Henan University of Science and Technology
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Abstract

本发明公开了一种用于治疗外伤止血或顽固性溃疡的中药,是由以下重量份的药物组成:蜈蚣50-55份、牡丹皮炭30-35份、重楼3-5份、三七3-5份、小蓟3-5份、煅石膏3-5份。本发明中药的发明人根据中医理论结合多年治疗经验,从中国的中草药库中选择6味药物进行配伍,制成本发明的用于治疗外伤止血或顽固性溃疡的中药,具有止血、消肿止疼、化瘀、软坚散结的作用。通过6年的临床试验,采用本发明的中药共治疗625例患者,其中有效率为96%,治愈率为86%,安全可靠,无副作用,用于治疗顽固性溃疡、大面积烧烫伤和止血。The invention discloses a traditional Chinese medicine for treating traumatic hemostasis or obstinate ulcer, which is composed of the following medicines in parts by weight: 50-55 parts of centipede, 30-35 parts of moutan cortex charcoal, 3-5 parts of chrysanthemum, and Panax notoginseng 3-5 parts, 3-5 parts of thistle, 3-5 parts of calcined gypsum. The inventor of the traditional Chinese medicine of the present invention combined with many years of treatment experience according to the theory of traditional Chinese medicine, selected 6 medicines from the Chinese herbal medicine library for compatibility, and made the traditional Chinese medicine for the treatment of traumatic bleeding or intractable ulcers of the present invention. Pain, blood stasis, softening and resolving the role of hard mass. Through 6 years of clinical trials, a total of 625 patients were treated with the traditional Chinese medicine of the present invention, wherein the effective rate was 96%, the cure rate was 86%, safe and reliable, without side effects, and used for the treatment of intractable ulcers, large area burns and scalds and hemostasis .

Description

一种用于治疗外伤止血或顽固性溃疡的中药A kind of traditional Chinese medicine for treating traumatic hemostasis or intractable ulcer

技术领域 technical field

本发明涉及一种用于治疗外伤止血或顽固性溃疡的中药。The invention relates to a traditional Chinese medicine for treating traumatic hemostasis or obstinate ulcer.

背景技术 Background technique

人们在日常工作和生活中,因外伤、烧伤和手术等各种原因导致的外伤出血及感染形成的顽固性溃疡,由于其高复发性和顽固性,常使西医治疗陷于对抗生素的过于依赖及耐药性的产生,甚至还要采取植皮手术,其疗程加重了病人的痛苦并提高了治疗费用。In people's daily work and life, the refractory ulcers formed by traumatic bleeding and infection caused by various reasons such as trauma, burns and operations often make Western medicine treatment fall into the over-reliance on antibiotics and The emergence of drug resistance even requires skin grafting, which aggravates the suffering of patients and increases the cost of treatment.

发明内容 Contents of the invention

本发明的目的是提供一种用于治疗外伤止血或顽固性溃疡的中药。The object of the present invention is to provide a traditional Chinese medicine for treating traumatic hemostasis or intractable ulcer.

为了实现以上目的,本发明所采用的技术方案是:一种用于治疗外伤止血或顽固性溃疡的中药,是由以下重量份的组分组成:蜈蚣50-55份、牡丹皮炭30-35份、重楼3-5份、三七3-5份、小蓟3-5份、煅石膏3-5份。In order to achieve the above object, the technical solution adopted in the present invention is: a kind of Chinese medicine for the treatment of trauma hemostasis or intractable ulcer, is made up of the following components by weight: centipede 50-55 parts, moutan cortex charcoal 30-35 parts 3-5 parts, 3-5 parts of Zhonglou, 3-5 parts of Panax notoginseng, 3-5 parts of thistle, 3-5 parts of calcined gypsum.

所采用的剂型为散剂、膏剂或喷剂。The dosage form adopted is powder, ointment or spray.

本发明的用于治疗外伤止血或顽固性溃疡的中药:The Chinese medicine for the treatment of trauma hemostasis or intractable ulcer of the present invention:

蜈蚣:为节肢动物蜈蚣科动物多棘巨蜈蚣Scolopendra subspinipes的干燥全体。性甘,微寒,入肝、心二经。功效:息风止痉、消肿解毒。主治惊痫抽搐、破伤风、面瘫者。用于瘰疬结核、疮痈肿毒等症。蜈蚣有组织胺样物质和溶血性蛋白等。临床运用证明,能使溃疡迅速愈合。Centipede: The dry whole of the spiny giant centipede Scolopendra subspinipes of the arthropod Centipede. Sweet in nature, slightly cold, enters liver and heart meridians. Efficacy: Breathing wind, relieving convulsion, reducing swelling and detoxification. Indications convulsions convulsions, tetanus, facial paralysis. For diseases such as scrofula tuberculosis, sore carbuncle swollen poison. Centipedes have histamine-like substances and hemolytic proteins. Clinical application proves that it can make ulcers heal quickly.

牡丹皮炭:为毛茛科植物牡丹Paeonia suffruticosa干燥根皮。取牡丹皮片入锅内,以武火炒至焦黑色,存性为度,喷淋清水,取出,凉透后成牡丹皮炭。功效:具有清热凉血和活血散瘀的功效,可治疗痈肿疮毒、跌扑伤痛和风湿热痹。Moutan Bark Charcoal: It is the dried root bark of Paeonia suffruticosa. Take peony skin slices into the pot, stir-fry them with high fire until they are burnt black, when they are stable, spray them with clean water, take them out, and turn them into peony skin charcoal after cooling. Efficacy: It has the effects of clearing heat and cooling blood, promoting blood circulation and dissipating blood stasis, and can treat carbuncle sores, bruises, and rheumatism-heat arthralgia.

重楼:为百合科植物七叶一枝花Paris polyphylla的干燥根茎。除去杂质,洗净,润透,切薄片,晒干。性苦,微寒;有小毒。归肝经。功效:清热解毒,消肿止痛。用于疔疮痈肿,咽喉肿痛,毒蛇咬伤,跌扑伤痛,惊风抽搐。Chonglou: It is the dry rhizome of Paris polyphylla, a plant of the family Liliaceae. Remove impurities, wash, moisten thoroughly, cut into thin slices, and dry in the sun. Bitter in nature, slightly cold; slightly poisonous. Return liver channel. Efficacy: clearing heat and detoxifying, reducing swelling and relieving pain. For boils and carbuncles, sore throat, poisonous snake bites, pain from falls, convulsions and convulsions.

三七:为五加科植物三七Panax notoginseng的干燥根。秋季花开前采挖,洗净,分开主根、支根及茎基,干燥。支根习称“筋条”,茎基习称“剪口”。性甘、微苦,温。归肝、胃经。功效:散瘀止血,消肿定痛。用于吐血,衄血,便血,崩漏,外伤出血,胸腹剌痛,跌扑肿痛。Radix Notoginseng: It is the dried root of Panax notoginseng of Araliaceae plant. Excavate before the flowers bloom in autumn, wash, separate the main root, branch root and stem base, and dry. Branch roots are commonly called "tendons", and stem bases are commonly called "shears". Sweet in nature, slightly bitter, warm. Return liver, stomach warp. Efficacy: dissipating blood stasis to stop bleeding, reducing swelling and relieving pain. For hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, chest and abdomen stabbing pain, tumbling and swelling pain.

小蓟:为菊科植物小蓟Cirsium setosum的全草或根。夏、秋二季花开时采割,除去杂质,洗净,稍润,切段,干燥。性甘、苦,凉。归心、肝经。功效:具有清热,止血,散瘀消肿的功效。Small thistle: the whole plant or root of Cirsium setosum, a plant of Compositae. Harvest when flowers bloom in summer and autumn, remove impurities, wash, moisten slightly, cut into sections, and dry. Nature is sweet, bitter, cool. GUIXIN, Liver Channel. Efficacy: It has the effects of clearing heat, stopping bleeding, dispelling blood stasis and reducing swelling.

煅石膏:为石膏的炮制品,煅后研末外用。性甘、辛、涩,寒,归肺、胃经。功效:具有生肌、敛疮和止血的功效。外治溃疡不敛、湿疹瘙痒、水火烫伤和外伤出血。Calcined gypsum: It is a processed product of gypsum, calcined and ground into powder for external use. Sweet, pungent, astringent, cold in nature, returns lung, stomach meridian. Efficacy: It has the effects of promoting muscle growth, suppressing sores and stopping bleeding. External treatment of ulcers, eczema itching, water and fire burns and traumatic bleeding.

本发明的用于治疗外伤止血或顽固性溃疡的中药可以制成散剂、膏剂或喷剂:The Chinese medicine for the treatment of trauma hemostasis or intractable ulcer of the present invention can be made into powder, ointment or spray:

散剂:将配方中的各药物组分研磨成粉状,混合过200目筛,制成散剂。Powder: Grind each drug component in the formula into powder, mix through a 200-mesh sieve, and make a powder.

膏剂:将粉末状的散剂以凡士林为基质,每100g凡士林加入15g散剂,拌匀制成膏剂。Ointment: take vaseline as the base of the powdered powder, add 15g of powder for every 100g of petroleum jelly, mix well to make ointment.

喷剂:将粉状的散剂用10%乙醇提取,每20g散剂加入10%乙醇至100ml,混匀消毒制成喷剂。Spray: Extract the powdered powder with 10% ethanol, add 10% ethanol to 100ml per 20g powder, mix and sterilize to make a spray.

也可以取粉末状散剂40克,羟基纤维素钠5克,蒸馏水加至100毫升拌成糊状,倒在400平方厘米的玻璃板上成1毫米薄膜,晾干或烘干,切成所需大小,随用随取,研磨成散剂撒于创面。You can also take 40 grams of powdered powder, 5 grams of sodium hydroxycellulose, add distilled water to 100 ml and mix into a paste, pour it on a glass plate of 400 square centimeters to form a 1 mm film, dry or dry, cut into desired Size, take as needed, grind into powder and sprinkle on the wound.

本发明的用于治疗外伤止血或顽固性溃疡的中药为外用药,使用时将散剂、膏剂或喷剂敷于患处即可。The traditional Chinese medicine for treating traumatic hemostasis or intractable ulcer of the present invention is an external medicine, and powder, ointment or spray can be applied to the affected part during use.

本发明中药的发明人根据中医理论结合多年治疗经验,从中国的中草药库中选择6味药物进行配伍,制成本发明的用于治疗外伤止血或顽固性溃疡的中药,具有止血、化瘀、消肿止疼、软坚散结的作用。通过6年的临床试验,采用本发明的中药共治疗325例患者,其中有效率为96%,治愈率为86%,安全可靠,无副作用,用于治疗顽固性溃疡、大面积烧烫伤和止血,尤其是对需要植皮的大面积溃疡比临床常用的呋喃西林、生理盐水或其它抗生素药物治疗溃疡可缩短一半时间。其疗效判断标准为患者的病痛程度、止血时间和治愈时间长短,是否感染炎症或合并型感染,皮肤的起皱程度和愈后疤痕的深浅和大小等。有效的性状为减轻患者的疼痛,止血时间和治愈时间较短;痊愈后留下疤痕的皮肤部位起皱程度较浅,颜色沉着较少并接近本底皮肤。The inventor of the Chinese medicine of the present invention combines years of treatment experience with the theory of traditional Chinese medicine, selects 6 medicines from the Chinese herbal medicine storehouse for compatibility, and makes the Chinese medicine for the treatment of traumatic hemostasis or intractable ulcer of the present invention, which has the functions of hemostasis, blood stasis, The effect of reducing swelling and relieving pain, softening and resolving hard masses. Through 6 years of clinical trials, a total of 325 patients were treated with the traditional Chinese medicine of the present invention, wherein the effective rate was 96%, the cure rate was 86%, safe and reliable, without side effects, and used for the treatment of intractable ulcers, large area burns and scalds and hemostasis , especially for large-area ulcers that require skin grafting, it can shorten the time by half compared with nitrofurazone, normal saline or other antibiotics commonly used in clinical treatment of ulcers. The criteria for judging the curative effect are the degree of pain of the patient, the duration of hemostasis and healing time, whether there is inflammation or co-infection, the degree of wrinkling of the skin, and the depth and size of the scar after healing. The effective properties are to relieve the pain of the patient, and the hemostasis time and healing time are shorter; the wrinkled degree of the skin part of the scar left after the recovery is lighter, the color is less pigmented, and it is close to the background skin.

本发明是在中国专利ZL98108659.4“治疗顽固性溃疡的红药及其制作方法”的基础上进行改良,通过添加了牡丹皮炭、三七和小蓟等药材以增强了止血功能,同时在顽固性溃疡的治疗方面,不再使用可能对敏感皮肤有刺激作用的蝎子、血竭和蓖麻子等药物,采用更加安全可靠的重楼发挥清除热毒作用,以治疗顽固性溃疡带来的疔疮痈肿。同时在中药配伍上进一步明确了蜈蚣在配方中的“君药”和牡丹皮炭的“臣药”地位,符合君臣佐使的配方原则。在经济效益上,新用配方的成本较原有配方低廉,且易获得制取。The present invention is improved on the basis of Chinese patent ZL98108659.4 "Red medicine for treating obstinate ulcer and its preparation method". In the treatment of intractable ulcers, we no longer use scorpion, blood jellyfish and castor beans and other drugs that may be irritating to sensitive skin, and use more safe and reliable Chonglou to play a role in removing heat and toxins to treat furuncles caused by intractable ulcers. Sores and carbuncles. At the same time, in the compatibility of traditional Chinese medicine, the status of centipede as "monarch drug" and Moutan skin charcoal as "minister drug" in the formula is further clarified, which is in line with the formula principle of monarch, minister and assistant. In terms of economic benefits, the cost of the new formula is lower than that of the original formula, and it is easy to obtain and prepare.

具体实施方式 Detailed ways

实施例1Example 1

本实施例的用于治疗外伤止血或顽固性溃疡的中药是由以下重量份的药物组成:蜈蚣50份、牡丹皮炭30份、重楼5份、三七5份、小蓟5份、煅石膏4份。所采用的剂型为散剂。The traditional Chinese medicine used for the treatment of traumatic hemostasis or intractable ulcer in this embodiment is composed of the following medicines in parts by weight: 50 parts of centipede, 30 parts of moutan cortex charcoal, 5 parts of Chonglou, 5 parts of Panax notoginseng, 5 parts of small thistle, calcined 4 parts of gypsum. The dosage form adopted is powder.

实施例2Example 2

本实施例的用于治疗外伤止血或顽固性溃疡的中药是由以下重量份的药物组成:蜈蚣55份、牡丹皮炭33份、重楼3份、三七3份、小蓟3份、煅石膏5份。所采用的剂型为膏剂。The traditional Chinese medicine used for the treatment of traumatic hemostasis or intractable ulcer of the present embodiment is made up of the medicine of following parts by weight: 55 parts of centipede, 33 parts of moutan cortex charcoal, 3 parts of Chonglou, 3 parts of Panax notoginseng, 3 parts of small thistle, calcined 5 parts of gypsum. The dosage form adopted is ointment.

实施例3Example 3

本实施例的用于治疗外伤止血或顽固性溃疡的中药是由以下重量份的药物组成:蜈蚣53份、牡丹皮炭35份、重楼4份、三七4份、小蓟4份、煅石膏3份。所采用的剂型为喷剂。The traditional Chinese medicine used for the treatment of traumatic hemostasis or intractable ulcer of the present embodiment is composed of the following medicines in parts by weight: 53 parts of centipede, 35 parts of moutan cortex charcoal, 4 parts of Chonglou, 4 parts of Panax notoginseng, 4 parts of small thistle, calcined 3 parts of gypsum. The dosage form adopted is a spray.

具体的病例:Specific cases:

患者张某,女,38岁,2006年10月3日因开水烫伤后形成顽固性溃疡主诉门诊治疗,曾口服阿奇霉素,肌肉注射青霉素,以呋喃西林、生理盐水或碘伏换药,创面均不能有效愈合,接诊后,仅每日喷洒散剂,经15日后,创面完全愈合。Patient Zhang, female, 38 years old, complained of outpatient treatment due to intractable ulcers after being scalded by boiling water on October 3, 2006. She had taken azithromycin orally, injected penicillin intramuscularly, and changed dressings with nitrofurazone, normal saline or povidone iodine, but none of the wounds were effective. Healing, after receiving a doctor, only spray powder every day, after 15 days, the wound surface heals completely.

患者金某,男,56岁,2008年5月3日因背部生疮、伴剧痛主诉门诊治疗,曾口服阿奇霉素、红霉素等,涂抹拔毒膏1周,创面均不能有效愈合,接诊后,接诊后,仅每日涂抹膏剂,经6日后,创面完全愈合。Patient Jin, male, 56 years old, complained of outpatient treatment on May 3, 2008 due to sores on his back and severe pain. Examine after, after receiving an examination, only smear ointment every day, after 6 days, wound surface heals completely.

患者李某,女,12岁,2010年因外伤感染后导致膝盖部溃疡,曾静脉滴注青霉素,以呋喃西林、生理盐水或碘伏换药,创面均不能有效愈合,接诊后,仅每日喷洒液体喷剂,经7日后,创面完全愈合。Patient Li, female, 12 years old, had a knee ulcer caused by a traumatic infection in 2010. She had been given intravenous infusion of penicillin and changed dressings with nitrofurazone, normal saline or povidone iodine, but the wound could not heal effectively. Spray the liquid spray, and after 7 days, the wound surface is completely healed.

Claims (2)

1.一种用于治疗外伤止血或顽固性溃疡的中药,其特征在于:是由以下重量份的药物组成:蜈蚣50-55份、牡丹皮炭30-35份、重楼3-5份、三七3-5份、小蓟3-5份、煅石膏3-5份。1. a kind of Chinese medicine that is used for the treatment of trauma hemostasis or intractable ulcer is characterized in that: be made up of the medicine of following weight part: centipede 50-55 part, moutan cortex charcoal 30-35 part, polyphylla 3-5 part, 3-5 parts of notoginseng, 3-5 parts of thistle, 3-5 parts of calcined gypsum. 2.根据权利要求1所述的用于治疗外伤止血或顽固性溃疡的中药,其特征在于:所采用的剂型为散剂、膏剂或喷剂。2. The traditional Chinese medicine for treating traumatic hemostasis or refractory ulcer according to claim 1, characterized in that: the dosage form adopted is powder, ointment or spray.
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