CN1047087C

CN1047087C - Dysmenorrhoea powder and its production technology

Info

Publication number: CN1047087C
Application number: CN93111705A
Authority: CN
Inventors: 孙宁铨
Original assignee: Jiangsu Provincial Insititute of Traditional Chinese Medicine
Current assignee: Jiangsu Provincial Insititute of Traditional Chinese Medicine
Priority date: 1993-08-11
Filing date: 1993-08-11
Publication date: 1999-12-08
Anticipated expiration: 2013-08-11
Also published as: CN1098642A

Abstract

The present invention relates to dysmenorrhoea powder and a production technology thereof. The present invention is characterized in that the dysmenorrhoea powder is prepared from 10 to 16 wt% of safflower, 5 to 10 wt% of angelica, 10 to 16 wt% of red sage root, 5 to 10 wt% of trogopterus dung, 25 to 6 wt% of common aucklandia root, 10 to 16 wt% of corydalis tuber, 25 to 6 wt% of cassia bark, 5 to 10 wt% of common prism tuber and 5 to 10 wt% of zedoary. The preparation technology for the dysmenorrhoea powder comprises the following steps of boiling, steam distillation, extraction, concentration, precipitation, creaming, drying, etc. The dysmenorrhoea powder has a good therapeutic effect and no obvious side effect for on female functional dysmenorrhea, and the effective rate of the dysmenorrhoea powder reaches more than 87% through clinic probation.

Description

Dysmenorrhoea powder and production technology thereof

The dysmenorrhoea powder that the present invention relates to a kind of women's of treatment primary dysmenorrhea disease with and preparation technology.

Women's primary dysmenorrhea is a kind of common disease, and its sickness rate is higher.At present the method for this disease of treatment has dialectical the executing of Chinese medicine to control, and its curative effect is higher, is easy and high than the curative effect of domestic and international modern medicine, but lacks the scientific experiments data of modern medicine.And the modern medicine etiological study gos deep into clear both at home and abroad, the treatment of physical therapy, endocrine therapy and pain relieving spasmolytic is arranged until operative treatment (as expanding the palace and drawing together palace, uterus suspention, rumpbone neurectomy) etc. aspect treatment, have the problem of disturbing the endocrine physiological mechanism to exist with hormone therapy, and curative effect is not consolidated yet; With operative treatment the function of human body is had certain damage, curative effect is also not ideal simultaneously.

In view of this, the purpose of this invention is to provide a kind of curative effect height, little Chinese medicine electuary and the corresponding production technology thereof of side effect.

Dysmenorrhoea powder provided by the present invention, its technical solution is: according to traditional Chinese medical science dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, the theory of regulating QI to relieve pain, by weight Flos Carthami 10-16%, Radix Angelicae Sinensis 5-10%, Radix Salviae Miltiorrhizae 10-16%, Oletum Trogopterori 5-10%, Radix Aucklandiae 6-25%, Rhizoma Corydalis 10-16%, Cortex Cinnamomi 6-25%, rhizoma sparganic 5-10%, the ratio of Rhizoma Curcumae 5-10% is formulated.

According to the dysmenorrhoea powder that above-mentioned technical solution provided, its production technology is as follows: at first seven flavor Chinese medicines except that the Radix Aucklandiae, Cortex Cinnamomi in the above-mentioned technical solution are soaked 30 fens kinds, boil and boil three times, boil for the first time and boil 60 minutes, second, third time respectively boiled and boiled 30 fens kinds, filter respectively, gained filtrate is merged, standby; Then the Radix Aucklandiae, Cortex Cinnamomi are smashed to pieces, carried out steam distillation, collect the volatile oil (extract appropriate to the occasion two kinds of little and bigger than water volatile oil extractors extract simultaneously than water with proportion) of different specific weight respectively.Infusion leaches standby; Again that above-mentioned two parts are standby filter liquor merges, and is concentrated into a certain amount ofly, adds 95% long-pending ethanol of its diploid, stirs, and places to make it in 12 hours to precipitate, and leaches alcoholic solution, is concentrated into flowing soaking paste.Add Icing Sugar, dextrin, its ratio is an Icing Sugar: dextrin: extractum is 1.5: 1: 1, and mixing is made suitable granule, drying; With standby volatile oil mixing, after the ether dilution, spray people's granule again, waiting fully, absorption back mixing gets product.

The present invention observes proof through clinical experiment to be had microcirculation improvement, reduces prostaglandin f in menses and the endometrium ₂The effect of alpha content, and can alleviate the uterine smooth muscle spasm, and do not have obvious mouldiness reaction, be applicable to functional dysmenorrhoea disease.Through experimental therapy 198 examples, the clinical treatment effective percentage reaches 87.38%.

Embodiment; Get Flos Carthami 15.5%, Radix Angelicae Sinensis 9%, Radix Salviae Miltiorrhizae 15.5%, Oletum Trogopterori 9%, the Radix Aucklandiae 8.75%, Rhizoma Corydalis 15.5%, Cortex Cinnamomi 8.75%, rhizoma sparganic 9%, Rhizoma Curcumae 9%, through the formulated dysmenorrhoea powder of above-mentioned technology, it is remarkable to be applied to clinical effectiveness, and effective percentage reaches more than 87%.

Claims

1, a kind of dysmenorrhoea powder is characterized in that it is made than raw material by following weight: Flos Carthami 10-16%, Radix Angelicae Sinensis 5-10%, Radix Salviae Miltiorrhizae 10-16%, Oletum Trogopterori 5-10%, Radix Aucklandiae 6-25%, Rhizoma Corydalis 10-16%, Cortex Cinnamomi 6-25%, rhizoma sparganic 5-10%, Rhizoma Curcumae 5-10%.

2, according to the described dysmenorrhoea powder of claim 1, the weight ratio that it is characterized in that each medicine is a Flos Carthami 15.5%, Radix Angelicae Sinensis 9%, Radix Salviae Miltiorrhizae 15.5%, Oletum Trogopterori 9%, the Radix Aucklandiae 8.75%, Rhizoma Corydalis 15.5%, Cortex Cinnamomi 8.75%, rhizoma sparganic 9%, Rhizoma Curcumae 9%.

3, a kind of production claim 1 or the 2 described diffusing production technologies of dysmenorrheas is characterized in that:

(1) by claim 1 or 2 described weight ratios, get seven flavor Chinese medicines except that the Radix Aucklandiae, Cortex Cinnamomi, soaked 30 minutes, boil and boil three times, to boil for the first time and boil 60 minutes, second, third time respectively boiled and boiled 30 minutes, filters respectively, and gained filtrate is merged, and be standby;

(2) get the Radix Aucklandiae, Cortex Cinnamomi is smashed to pieces, carries out steam distillation, two kinds of little and bigger than water volatile oil extractors extract simultaneously than water with proportion, collect volatile oil, the infusion of different specific weight respectively, leach standby:

(3) (1) is described filtrate and (2) described infusion merge, and concentrate, and add 95% long-pending ethanol of diploid, stir, and place and make it precipitation in 12 hours, leach alcoholic solution, are concentrated into flowing soaking paste;

(4) get (3) described paste, add Icing Sugar, dextrin, its ratio is a paste: Icing Sugar: dextrin is 1: 1.5: 1, and mixing is made suitable granule, drying;

(5) get (2) described volatile oil mixing, after the ether dilution, spray into (4) described granule, waiting fully absorbs, and mixing gets product.