CN104706991A - Traditional Chinese medicine oral liquid for treating bovine nephritis and preparation method thereof - Google Patents
Traditional Chinese medicine oral liquid for treating bovine nephritis and preparation method thereof Download PDFInfo
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- CN104706991A CN104706991A CN201310681812.2A CN201310681812A CN104706991A CN 104706991 A CN104706991 A CN 104706991A CN 201310681812 A CN201310681812 A CN 201310681812A CN 104706991 A CN104706991 A CN 104706991A
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Abstract
The invention provides a traditional Chinese medicine oral liquid for treating bovine nephritis and a preparation method thereof. The traditional Chinese medicine oral liquid comprises, by weight, 2-10 parts of honeysuckle flower, 2-10 parts of fructus forsythia, 4-20 parts of raw rehmannia root, 1-8 parts of anemarrhena, 2-10 parts of polyporus, 2-10 parts of rhizoma alismatis, 2-10 parts of plantain seed, 1-8 parts of root bark of the peony tree, 14-38 parts of fresh couchgrass root, 1-8 parts of mulberry bark, 1-8 parts of lophatherum gracile and 1-8 parts of fringed pink. The traditional Chinese medicine oral liquid has good effects on bovine nephritis caused by infection, poisoning or allergic reaction and can effectively prevent bovine kidney enlargement, chronic nephritis, proteinuria and hematuria.
Description
Technical field
The invention belongs to field of veterinary, especially a kind ofly treat Chinese medicine oral liquid of Ren Bovis seu Bubali inflammation and preparation method thereof.
Background technology
Nephritis is the inflammation of excess of the kidney matter.Pathological changes is glomerule vascular inflammation mainly, therefore is also called glomerulonephritis, with the degeneration pathological changes that renal tubules overhead is slight.Its Clinical symptoms is edema under blood albumin minimizing, serious albuminuria and extremity, front and abdomen.Cattle glomerulonephritis is rare clinically.
This sick many secondary or concurrent in some infectious disease, as foot and mouth disease, anthrax, hueppe's disease etc.The specific antibody of the infringement glomerular basement membrane generally only produced in the pathogen of glomerule and toxin Sum decomposition product thereof and antibody complex or infected cattle because of calmness, combined effect and cause the damage of glomerule.
Milch cow glomerulonephritis is also often secondary to endometritis, mastitis, pleuritis and peritonitis, because inflammatory exudate and the corrupt catabolite of other albumen continue the stimulation to kidney, causes producing a large amount of antibody and bringing out this disease.Cold stimulation, the defensive enginery of body and kidney reduces, and can bring out this disease.
The pathogeny of this disease is not yet very clear.Now be considered to anaphylaxis.Intolerance factors, by vasomotor nerve, causes glomerular capillary spasmodic contraction and inflammatory reaction, causes blood circulation of kidney obstacle, and urinary system is in disorder, urinate minimizing or anuria.Due to the moisture in body, sodium chloride with can not excrete containing nitrogen metabolism dead end product and store up in body and stay, renal edema and azotemic uremia will be caused.
The damage of glomerular capillary and the thin urinary catheter of kidney and the eliminating of inflammatory products, be mixed with erythrocyte, leukocyte, renal epithelial cell and a large amount of albumen in urine.In blood, albumin is discharged by kidney in a large number, causes hypoalbuminemia, blood colloid osmotic pressure is changed, water metabolism Balance disorders, has increased the weight of anasarcous degree.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine oral liquid for the treatment of Ren Bovis seu Bubali inflammation, the active component of this oral liquid prescription is natural Chinese medicinal herb, for treatment owing to infecting, the Ren Bovis seu Bubali inflammation that causes of the factor such as poisoning and allergy has good curative effect, this oral liquid adds in the drinking-water of cattle on a small quantity, can effectively prevent the diseases such as Ren Bovis seu Bubali enlargement, chronic nephritis, albuminuria, hematuria.The scorching Be very effective of this oral liquid treatment Ren Bovis seu Bubali, cures fast, not easily recurs, have no side effect, without any drug residue.
Another object of the present invention is to provide a kind of preparation method for the treatment of the Chinese medicine oral liquid of Ren Bovis seu Bubali inflammation.
The present invention is achieved by the following technical solutions:
Treat a Chinese medicine oral liquid for Ren Bovis seu Bubali inflammation, component and the ratio of weight and number thereof of this oral liquid are respectively:
Treat a preparation method for the Chinese medicine oral liquid of Ren Bovis seu Bubali inflammation, the step of this preparation method is as follows:
(1) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Polyporus, Rhizoma Alismatis, Semen Plantaginis, Cortex Moutan, fresh cogongrass, Cortex Mori, Herba Lophatheri, Herba Dianthi is taken respectively by weight ratio, drop in Chinese medicine extracting tank through cleaning after demulcen is dried, add the drinking water of 5-10 times of inventory, being heated to water boiling decocts after 1-2 hour, extracting solution is sucked in extracting solution storage tank, obtain extracting solution A, for subsequent use;
(2) in above-mentioned Chinese medicine extracting tank, add the drinking water of 5-7 times of inventory again, be heated to boiling and decoct after 1-2 hour, extracting solution is sucked in extracting solution storage tank, merge with step (1) gained extracting solution A, obtain extracting solution B, for subsequent use;
(3) step (1) gained extracting solution B is entered I, II single-effect evaporator to stop to visor 2/3, heating is with steam pressure 0.09Mpa, and feed supplement is in time to normal level, double effect evaporator 15-20 minute discharge condensed water once, every two hours discharges the condensation vapour of heater once; When extracting solution B to be concentrated into density be 1.10-1.15g/ml, in imitating II, extracting solution B proceeds in I effect concentrated, when extracting solution B density reaches 1.15-1.20g/ml, extracting solution B is sucked in Alcohol-settling tank, when temperature reaches 40 DEG C, adds a certain amount of ethanol and stir, alcohol content is made to reach 50%, leave standstill 24 hours, obtain extracting solution C, for subsequent use;
(4) step (3) gained extracting solution C is sucked supernatant storage tank, resorb spherical concentration tank, open Steam Heating, Steam pressure control is being less than 0.1Mpa, and opens condensing hot air furnace condensed fluid (ethanol), when condensed fluid measures alcohol content for being less than 10%, stop collecting, it is 1.10-1.15g/ml that extracting solution C is concentrated into density, obtains concentrated solution D, for subsequent use;
(5) respectively sucrose, benzoic acid, ethyl hydroxybenzoate, caramel color are joined in step (4) gained concentrated solution D, suck in oral liquid dilute preparing tank after abundant stirring, adding appropriate purified water, to be stirred to density be 1.05g/ml-1.10g/ml, sterilizing after embedding, must treat the Chinese medicine oral liquid finished product of Ren Bovis seu Bubali inflammation.
The amount of the sucrose that described step (5) adds, benzoic acid, ethyl hydroxybenzoate, caramel color is respectively 10%, 0.3%, 0.2%, 0.3% of concentrated solution D volume.
Advantage of the present invention and beneficial effect are:
1. active component of the present invention is natural Chinese medicinal herb, and crude drug all can commercially have been bought, and cheap.
2. the present invention for treatment owing to infecting, the Ren Bovis seu Bubali inflammation that causes of the factor such as poisoning and allergy has good curative effect, this oral liquid adds in the drinking-water of cattle on a small quantity, can effectively prevent the diseases such as Ren Bovis seu Bubali enlargement, chronic nephritis, albuminuria, hematuria.
3. use the present invention, effect stability, scalable function, adjustment immunity of organism, control inflammation reaction, suppresses the progress of renal fibrosis, repair impaired renal tissue, thus control protein loss.
4. cost of the present invention is low, free from environmental pollution, and therapeutic effect is remarkable, cures fast, not easily recurs, have no side effect, drug residue free.
5. invention increases correctives, improve palatability.
Detailed description of the invention
The present invention is described in further detail by following examples.It should be noted that: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Flos Lonicerae in the present invention, Fructus Forsythiae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Polyporus, Rhizoma Alismatis, Semen Plantaginis, Cortex Moutan, fresh cogongrass, Cortex Mori, Herba Lophatheri, Herba Dianthi all commercially can be bought and obtain.
Embodiment 1
Treat a Chinese medicine oral liquid for Ren Bovis seu Bubali inflammation, component and the weight thereof of its Chinese medicine oral liquid are respectively: Flos Lonicerae 30kg, Fructus Forsythiae 30kg, Radix Rehmanniae 60kg, Rhizoma Anemarrhenae 20kg, Polyporus 30kg, Rhizoma Alismatis 30kg, Semen Plantaginis 30kg, Cortex Moutan 20kg, fresh cogongrass 130kg, Cortex Mori 20kg, Herba Lophatheri 20kg, Herba Dianthi 20kg.
Treat a preparation method for the Chinese medicine oral liquid of Ren Bovis seu Bubali inflammation, the step of this preparation method is as follows:
(1) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Polyporus, Rhizoma Alismatis, Semen Plantaginis, Cortex Moutan, fresh cogongrass, Cortex Mori, Herba Lophatheri, Herba Dianthi is taken respectively by weight ratio, drop in Chinese medicine extracting tank through cleaning after demulcen is dried, add the drinking water of 8 times of inventorys, be heated to water boiling decoction after 1.5 hours, extracting solution is sucked in extracting solution storage tank, obtain extracting solution A, for subsequent use;
(2) in above-mentioned Chinese medicine extracting tank, add the drinking water of 6 times of inventorys again, be heated to boiling decoction after 1.5 hours, extracting solution sucked in extracting solution storage tank, merge with step (1) gained extracting solution A, obtain extracting solution B, for subsequent use;
(3) step (1) gained extracting solution B is entered I, II single-effect evaporator to stop to visor 2/3, heating is with steam pressure 0.09Mpa, and feed supplement is in time to normal level, double effect evaporator 18 minutes discharge condensed waters once, every two hours discharge the condensation vapour of heater once; When extracting solution B to be concentrated into density be 1.13g/ml, in imitating II, extracting solution B proceeds in I effect concentrated, when extracting solution B density reaches 1.18g/ml, extracting solution B is sucked in Alcohol-settling tank, when temperature reaches 40 DEG C, adds a certain amount of ethanol and stir, alcohol content is made to reach 50%, leave standstill 24 hours, obtain extracting solution C, for subsequent use;
(4) step (3) gained extracting solution C is sucked supernatant storage tank, resorb spherical concentration tank, open Steam Heating, Steam pressure control at 0.09Mpa, and opens condensing hot air furnace condensed fluid (ethanol), when condensed fluid measurement alcohol content is 9%, stop collecting, it is 1.13g/ml that extracting solution C is concentrated into density, obtains concentrated solution D, for subsequent use;
(5) in step (4) gained concentrated solution D, the sucrose of its volume 10%, benzoic acid, the ethyl hydroxybenzoate of 0.2%, the caramel color of 0.3% of 0.3% is added respectively, suck in oral liquid dilute preparing tank after abundant stirring, adding appropriate purified water, to be stirred to density be 1.08g/ml, sterilizing after embedding, must treat the Chinese medicine oral liquid finished product of Ren Bovis seu Bubali inflammation.
Embodiment 2
Treat a Chinese medicine oral liquid for Ren Bovis seu Bubali inflammation, component and the weight thereof of its Chinese medicine oral liquid are respectively: Flos Lonicerae 20kg, Fructus Forsythiae 20kg, Radix Rehmanniae 40kg, Rhizoma Anemarrhenae 10kg, Polyporus 20kg, Rhizoma Alismatis 20kg, Semen Plantaginis 20kg, Cortex Moutan 10kg, fresh cogongrass 140kg, Cortex Mori 10kg, Herba Lophatheri 10kg, Herba Dianthi 10kg.
Treat a preparation method for the Chinese medicine oral liquid of Ren Bovis seu Bubali inflammation, the step of this preparation method is as follows:
(1) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Polyporus, Rhizoma Alismatis, Semen Plantaginis, Cortex Moutan, fresh cogongrass, Cortex Mori, Herba Lophatheri, Herba Dianthi is taken respectively by weight ratio, drop in Chinese medicine extracting tank through cleaning after demulcen is dried, add the drinking water of 5 times of inventorys, be heated to water boiling decoction after 1 hour, extracting solution is sucked in extracting solution storage tank, obtain extracting solution A, for subsequent use;
(2) in above-mentioned Chinese medicine extracting tank, add the drinking water of 5 times of inventorys again, be heated to boiling decoction after 1 hour, extracting solution sucked in extracting solution storage tank, merge with step (1) gained extracting solution A, obtain extracting solution B, for subsequent use;
(3) step (1) gained extracting solution B is entered I, II single-effect evaporator to stop to visor 2/3, heating is with steam pressure 0.09Mpa, and feed supplement is in time to normal level, double effect evaporator 15 minutes discharge condensed waters once, every two hours discharge the condensation vapour of heater once; When extracting solution B to be concentrated into density be 1.10g/ml, in imitating II, extracting solution B proceeds in I effect concentrated, when extracting solution B density reaches 1.15g/ml, extracting solution B is sucked in Alcohol-settling tank, when temperature reaches 40 DEG C, adds a certain amount of ethanol and stir, alcohol content is made to reach 50%, leave standstill 24 hours, obtain extracting solution C, for subsequent use;
(4) step (3) gained extracting solution C is sucked supernatant storage tank, resorb spherical concentration tank, open Steam Heating, Steam pressure control at 0.09Mpa, and opens condensing hot air furnace condensed fluid (ethanol), when condensed fluid measurement alcohol content is 9%, stop collecting, it is 1.10g/ml that extracting solution C is concentrated into density, obtains concentrated solution D, for subsequent use;
(5) in step (4) gained concentrated solution D, the sucrose of its volume 10%, benzoic acid, the ethyl hydroxybenzoate of 0.2%, the caramel color of 0.3% of 0.3% is added respectively, suck in oral liquid dilute preparing tank after abundant stirring, adding appropriate purified water, to be stirred to density be 1.05g/ml, sterilizing after embedding, must treat the Chinese medicine oral liquid finished product of Ren Bovis seu Bubali inflammation.
Embodiment 3
Treat a Chinese medicine oral liquid for Ren Bovis seu Bubali inflammation, component and the weight thereof of its Chinese medicine oral liquid are respectively: Flos Lonicerae 100kg, Fructus Forsythiae 100kg, Radix Rehmanniae 200kg, Rhizoma Anemarrhenae 80kg, Polyporus 100kg, Rhizoma Alismatis 100kg, Semen Plantaginis 100kg, Cortex Moutan 80kg, fresh cogongrass 380kg, Cortex Mori 80kg, Herba Lophatheri 80kg, Herba Dianthi 80kg.
Treat a preparation method for the Chinese medicine oral liquid of Ren Bovis seu Bubali inflammation, the step of this preparation method is as follows:
(1) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Polyporus, Rhizoma Alismatis, Semen Plantaginis, Cortex Moutan, fresh cogongrass, Cortex Mori, Herba Lophatheri, Herba Dianthi is taken respectively by weight ratio, drop in Chinese medicine extracting tank through cleaning after demulcen is dried, add the drinking water of 10 times of inventorys, be heated to water boiling decoction after 2 hours, extracting solution is sucked in extracting solution storage tank, obtain extracting solution A, for subsequent use;
(2) in above-mentioned Chinese medicine extracting tank, add the drinking water of 7 times of inventorys again, be heated to boiling decoction after 2 hours, extracting solution sucked in extracting solution storage tank, merge with step (1) gained extracting solution A, obtain extracting solution B, for subsequent use;
(3) step (1) gained extracting solution B is entered I, II single-effect evaporator to stop to visor 2/3, heating is with steam pressure 0.09Mpa, and feed supplement is in time to normal level, double effect evaporator 20 minutes discharge condensed waters once, every two hours discharge the condensation vapour of heater once; When extracting solution B to be concentrated into density be 1.15g/ml, in imitating II, extracting solution B proceeds in I effect concentrated, when extracting solution B density reaches 1.20g/ml, extracting solution B is sucked in Alcohol-settling tank, when temperature reaches 40 DEG C, adds a certain amount of ethanol and stir, alcohol content is made to reach 50%, leave standstill 24 hours, obtain extracting solution C, for subsequent use;
(4) step (3) gained extracting solution C is sucked supernatant storage tank, resorb spherical concentration tank, open Steam Heating, Steam pressure control at 0.09Mpa, and opens condensing hot air furnace condensed fluid (ethanol), when condensed fluid measurement alcohol content is 9%, stop collecting, it is 1.15g/ml that extracting solution C is concentrated into density, obtains concentrated solution D, for subsequent use;
(5) in step (4) gained concentrated solution D, the sucrose of its volume 10%, benzoic acid, the ethyl hydroxybenzoate of 0.2%, the caramel color of 0.3% of 0.3% is added respectively, suck in oral liquid dilute preparing tank after abundant stirring, adding appropriate purified water, to be stirred to density be 1.10g/ml, sterilizing after embedding, must treat the Chinese medicine oral liquid finished product of Ren Bovis seu Bubali inflammation.
Clinical trial
At the beginning of 2012, produce a collection of the present invention, for clinical trial by our company.205 the sick cattle of our company to the several cattle farm of periphery carry out free treatment, the usage and dosage of this product: can gavage, mix drink, spice: gavage, once a day, gavage 50ml at every turn, be used in conjunction 3-7 day; Mixed drink, every 200ml is watered 200kg, once a day, concentrates and drinks, be used in conjunction 4-6 days; Spice, every 200ml spice 50kg, once a day, concentrates and searches for food, be used in conjunction 3-5 time; Therapeutic outcome:
By finding out that to the therapeutic outcome of 205 cattle therapeutic effect of the present invention is remarkable, cure rate is high.The test group administration first day of the present invention, therapeutic effect is remarkable, and after administration 7d, cure rate reaches 96.75%, and conventional therapy group administration first day therapeutic effect is close with test group of the present invention, continues medication therapeutic effect and obviously declines.Therefore the present invention to owing to infecting, the Ren Bovis seu Bubali inflammation that causes of the factor such as poisoning or allergy has significant curative effect.
Claims (3)
1. treat a Chinese medicine oral liquid for Ren Bovis seu Bubali inflammation, it is characterized in that: component and the ratio of weight and number thereof of this Chinese medicine oral liquid are respectively:
2. treat a preparation method for the Chinese medicine oral liquid of Ren Bovis seu Bubali inflammation, it is characterized in that: the step of this preparation method is as follows:
(1) Flos Lonicerae, Fructus Forsythiae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Polyporus, Rhizoma Alismatis, Semen Plantaginis, Cortex Moutan, fresh cogongrass, Cortex Mori, Herba Lophatheri, Herba Dianthi is taken respectively by weight ratio, drop in Chinese medicine extracting tank through cleaning after demulcen is dried, add the drinking water of 5-10 times of inventory, being heated to water boiling decocts after 1-2 hour, extracting solution is sucked in extracting solution storage tank, obtain extracting solution A, for subsequent use;
(2) in above-mentioned Chinese medicine extracting tank, add the drinking water of 5-7 times of inventory again, be heated to boiling and decoct after 1-2 hour, extracting solution is sucked in extracting solution storage tank, merge with step (1) gained extracting solution A, obtain extracting solution B, for subsequent use;
(3) step (1) gained extracting solution B is entered I, II single-effect evaporator to stop to visor 2/3, heating is with steam pressure 0.09Mpa, and feed supplement is in time to normal level, double effect evaporator 15-20 minute discharge condensed water once, every two hours discharges the condensation vapour of heater once; When extracting solution B to be concentrated into density be 1.10-1.15g/ml, in imitating II, extracting solution B proceeds in I effect concentrated, when extracting solution B density reaches 1.15-1.20g/ml, extracting solution B is sucked in Alcohol-settling tank, when temperature reaches 40 DEG C, adds a certain amount of ethanol and stir, alcohol content is made to reach 50%, leave standstill 24 hours, obtain extracting solution C, for subsequent use;
(4) step (3) gained extracting solution C is sucked supernatant storage tank, resorb spherical concentration tank, open Steam Heating, Steam pressure control is being less than 0.1Mpa, and opens condensing hot air furnace ethanol condensed fluid, when ethanol condensed fluid measures alcohol content for being less than 10%, stop collecting, it is 1.10-1.15g/ml that extracting solution C is concentrated into density, obtains concentrated solution D, for subsequent use;
(5) respectively sucrose, benzoic acid, ethyl hydroxybenzoate, caramel color are joined step (4) institute
Obtain in concentrated solution D, suck in oral liquid dilute preparing tank after fully stirring, add appropriate purified water and be stirred to close
Degree is 1.05g/ml-1.10g/ml, and sterilizing after embedding, must treat the Chinese medicine oral liquid finished product of Ren Bovis seu Bubali inflammation.
3. the preparation method of the Chinese medicine oral liquid for the treatment of Ren Bovis seu Bubali inflammation according to claim 2, is characterized in that: the amount of the described sucrose added described in step (5), benzoic acid, ethyl hydroxybenzoate, caramel color is respectively 10%, 0.3%, 0.2%, 0.3% of concentrated solution D volume.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177574A (en) * | 2016-08-26 | 2016-12-07 | 黄平县重安镇种养殖专业合作社 | A kind of Chinese medicine formula treating Sanguis Bovis seu Bubali urine |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1883666A (en) * | 2006-05-24 | 2006-12-27 | 陈汝德 | Pharmaceutical composition for treating nephritis |
| CN101352518A (en) * | 2008-08-26 | 2009-01-28 | 荣玉明 | Chinese medicine for treating nephritis, kidney deficiency and renal failure and production method |
-
2013
- 2013-12-11 CN CN201310681812.2A patent/CN104706991A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1883666A (en) * | 2006-05-24 | 2006-12-27 | 陈汝德 | Pharmaceutical composition for treating nephritis |
| CN101352518A (en) * | 2008-08-26 | 2009-01-28 | 荣玉明 | Chinese medicine for treating nephritis, kidney deficiency and renal failure and production method |
Non-Patent Citations (1)
| Title |
|---|
| 谢永玉主编: "《中医效验方荟萃》", 31 July 2011 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177574A (en) * | 2016-08-26 | 2016-12-07 | 黄平县重安镇种养殖专业合作社 | A kind of Chinese medicine formula treating Sanguis Bovis seu Bubali urine |
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