CN104706840A - Compound tea tree essential oil for preventing and treating mosquito bite - Google Patents

Compound tea tree essential oil for preventing and treating mosquito bite Download PDF

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CN104706840A
CN104706840A CN201510161375.0A CN201510161375A CN104706840A CN 104706840 A CN104706840 A CN 104706840A CN 201510161375 A CN201510161375 A CN 201510161375A CN 104706840 A CN104706840 A CN 104706840A
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oil
tea tree
tree ethereal
compound recipe
bitten
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范永启
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Abstract

The invention discloses compound tea tree essential oil for preventing and treating mosquito bite, which is prepared from the following main raw materials in parts by mass: 6-12 parts of radix arnebiae seu lithospermi, 9-15 parts of Chinese angelica, 6-12 parts of tallow seeds, 4-9 parts of cortex moutan radicis, 4-9 parts of herba schizonepetae, 6-10 parts of croton tiglium, 8-12 parts of zaocys dhumnade, and appropriate amounts of thymianct linalool essential oil, niaouli essential oil, VE (Vitamin E), grape seed essential oil and tea tree essential oil. The compound tea tree essential oil is obtained through clinical practice summary for years, has the efficacies of removing heat, cooling blood, drawing out a poison and diminishing swelling, and can effectively prevent and treat the mosquito bite.

Description

The compound recipe tea tree ethereal oil that a kind of mosquito control is bitten
Technical field
The present invention relates to quintessence oil field, particularly relate to the compound recipe tea tree ethereal oil that a kind of mosquito control is bitten.
Background technology
The mosquito in summer brings very large harm, and drone sound is hovered in one's ear, disturbs one's sleep, and then has influence on new darg, studying and living, if by mosquito bite, will ache itch hard to bear, be on tenterhooks.More serious problem is that mosquito can propagate the diseases such as malaria, filaricide, epidemic encephalitis type B and dengue fever.In the face of the attack of mosquito, people are except carrying out environmental renovation and physical isolation, and hygienic insecticide and anophelifuge are the last strick precautions of the mosquito of control.
Publication No. CN 103622867 A(application number 201310557271.2) Chinese patent literature disclose a kind of to take natural plant essential oils as the perfume of main active ingredient, belong to daily chemical products technical field.The natural material used includes: Herba nepenthis, Radix Buddlejae Butterflybush, Flos Pelargonii, Herba Menthae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Fructus Caricae, radix valerianae, Folium Artemisiae Argyi, lindera thomsonii allen, light Jasminum lanceolarium Roxb., clover, Radix Inulae, Flos Matricariae chamomillae, Ramulus et Folium Cotini Coggygiae.Publication No. CN 102835428 A(application number 201210316045.0) Chinese patent literature disclose a kind of essential mosquito repellent, this anophelifuge is composed of the following components by mass percentage: citronella oil 30-80%, Fructus Citri Limoniae oil 5-30%, Oleum lavandula angustifolia 5-20%, Oleum menthae 1-10%, mugwort oil 1-10%, surplus is food stage 95% ethanol.Publication No. CN 103655338 A(application number 201310691835.1) Chinese patent literature disclose a kind of mosquito-repellent essential oil, belong to quintessence oil preparing technical field, wherein the weight portion of each component is Oleum Pelargonii Graveolentis 30 ~ 60 parts, Oleum menthae 20 ~ 40 parts, citronella oil 10 ~ 20 parts.
At present for preventing the product of mosquito bite, mostly containing irritant chemical additive, human body is easily had side effects, is not suitable for the crowd of each age group, therefore utilize quintessence oil unique effects, it is necessary that research and development have the compound essential Oil that mosquito control bites.
Summary of the invention
For the problem of prior art, the object of this invention is to provide the compound recipe tea tree ethereal oil that the wide mosquito control of a kind of Be very effective, the use safety suitability is bitten.
Technical scheme of the present invention is:
The compound recipe tea tree ethereal oil that mosquito control is bitten, is prepared from primarily of following raw materials according, is mass parts: Radix Arnebiae (Radix Lithospermi) 6-12; Radix Angelicae Sinensis 9-15; Semen Sapii 6-12; Cortex Moutan 4-9; Herba Schizonepetae 4-9; Fructus Crotonis 6-10; Zaocys 8-12; Linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE, Semen Vitis viniferae quintessence oil, tea tree ethereal oil are in right amount each.
Preferred version is, Radix Arnebiae (Radix Lithospermi) 8-10; Radix Angelicae Sinensis 11-13; Semen Sapii 8-10; Cortex Moutan 5-8; Herba Schizonepetae 5-8; Fructus Crotonis 7-9; Zaocys 9-11; Linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE, Semen Vitis viniferae quintessence oil, tea tree ethereal oil are in right amount each.
What be more preferably is, Radix Arnebiae (Radix Lithospermi) 9; Radix Angelicae Sinensis 12; Semen Sapii 9; Cortex Moutan 6.5; Herba Schizonepetae 6.5; Fructus Crotonis 8; Zaocys 10; Linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE, Semen Vitis viniferae quintessence oil, tea tree ethereal oil are in right amount each.
The preparation method of the compound recipe tea tree ethereal oil that described a kind of mosquito control is bitten, step is as follows:
(1) get Semen Sapii and Fructus Crotonis to clean, adding rice vinegar, to infiltrate 15-25 minute (preferred: to infiltrate 18-22 minute; Be more preferably: infiltrate 20 minutes), take out and be placed in frying pan, slow fire heats, and fry to dry, taking-up pulverizes and sieves;
(2) get Zaocys removing impurity, with water cleaning twice, be cut into strip, be placed in steamer, add yellow wine and steam 25-35 minute (preferred: to add yellow wine and steam 30 minutes), take out and pulverize into mud, mix with step (1) gained medicated powder, be added to supercritical CO together 2in extraction equipment, setting extracting pressure is 30MPa, and extraction temperature is 38 DEG C, and resolution temperature is 50 DEG C, and extraction terminates rear collection volatile oil;
(3) Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Cortex Moutan and Herba Schizonepetae are cleaned, shave, add warm water soaking 40-60 minute (preferably: soak 45-55 minute; Be more preferably: soak 50 minutes), then use volatile oil extractor continuous circumfluence extraction, collect volatile oil;
(4) blend step (2) (3) gained volatile oil, makes volatile oil A, by volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil, be added to respectively in Semen Vitis viniferae quintessence oil, stir, leave standstill after 10-16 hour and filter, bottling, obtains compound recipe tea tree ethereal oil.
The preparation method of the compound recipe tea tree ethereal oil that described a kind of mosquito control is bitten, it is (preferred: to pulverize 70-90 mesh sieve that step (1) pulverized 60-100 mesh sieve; Be more preferably: pulverized 80 mesh sieves).
The preparation method of the compound recipe tea tree ethereal oil that described a kind of mosquito control is bitten, it is (preferred: extraction time is 5-6 hour that step (2) extraction time is 4-7 hour; Be more preferably: extraction time is 5.5 hours).
The preparation method of the compound recipe tea tree ethereal oil that described a kind of mosquito control is bitten, the amount that step (3) adds warm water is that the 4-6 of raw materials quality is doubly (preferred: the amount adding warm water is 4.5-5.5 times of raw materials quality; Be more preferably: the amount adding warm water is 5 times of raw materials quality).
The preparation method of the compound recipe tea tree ethereal oil that described a kind of mosquito control is bitten, step (3) continuous circumfluence extraction 5-7 hour is (preferred: continuous circumfluence extraction 5.5-6.5 hour; Be more preferably: continuous circumfluence extraction 6 hours).
The preparation method of the compound recipe tea tree ethereal oil that described a kind of mosquito control is bitten, the mass ratio of step (4) volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil is 0.8:0.8:0.6:0.4:1.0.
The preparation method of the compound recipe tea tree ethereal oil that described a kind of mosquito control is bitten, the quality of step (4) Semen Vitis viniferae quintessence oil is volatile oil A, the 2-3 of linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass times (preferred: the quality of Semen Vitis viniferae quintessence oil is 2.5 times of volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass).
The compound recipe Camellia sinensis essential oil science that a kind of mosquito control provided by the invention is bitten, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, instant effect;
2, raw material selected by the present invention, safety has no side effect, applied widely;
3, this formula through clinical practice for many years sum up form, there is clearing away heat and cooling blood, draw out pus by applying a plaster to the affected part detumescence effect.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the compound recipe tea tree ethereal oil that a kind of mosquito control is bitten, be prepared from (every part of 10g) primarily of following raw materials according: Radix Arnebiae (Radix Lithospermi) 6 parts, Radix Angelicae Sinensis 9 parts, Semen Sapii 6 parts, Cortex Moutan 4 parts, Herba Schizonepetae 4 parts, Fructus Crotonis 6 parts, Zaocys 8 parts of linalool thyme oils are (purchased from Shanghai Po Li trade Co., Ltd, specification 50ml, article No. PET0701), Rhizoma Melaleuca Viridiflora quintessence oil is (purchased from Xu Lan bio tech ltd, Shenzhen, specification 10ml, article No. XLE300), VE(is purchased from Jiahe, the Holy Land, Shandong biological engineering company limited, specification 1000 IU/g), Semen Vitis viniferae quintessence oil is (purchased from Shanghai Hui En International Trading Company Ltd, specification 1000ml, article No. M-00265), tea tree ethereal oil is (purchased from Bao Tianman pharmaceutcal corporation, Ltd of Nan Zhao, specification 30ml, article No. HL015) in right amount each.The preparation method of the compound recipe tea tree ethereal oil that above-mentioned a kind of mosquito control is bitten is:
(1) get Semen Sapii and Fructus Crotonis to clean, add rice vinegar and infiltrate 15 minutes, take out and be placed in frying pan, slow fire heats, and fries to dry, takes out and pulverized 60 mesh sieves;
(2) get Zaocys removing impurity, with water cleaning twice, be cut into strip, be placed in steamer, add yellow wine and steam 25 minutes, take out and pulverize into mud, mix with step (1) gained medicated powder, be added to supercritical CO together 2in extraction equipment, setting extracting pressure is 30MPa, and extraction temperature is 38 DEG C, and resolution temperature is 50 DEG C, extracts 4 hours, terminates rear collection volatile oil;
(3) Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Cortex Moutan and Herba Schizonepetae are cleaned, shave, (warm water soaking 40 minutes, then uses volatile oil extractor continuous circumfluence extraction 5 hours, collects volatile oil to add raw materials quality 4 times;
(4) blend step (2) (3) gained volatile oil, make volatile oil A, by volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil, according to the mass ratio of 0.8:0.8:0.6:0.4:1.0, be added to respectively in Semen Vitis viniferae quintessence oil (its quality is 2 times of volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass), stir, leave standstill after 10-16 hour and filter, bottling, obtains compound recipe tea tree ethereal oil.
embodiment 2the compound recipe tea tree ethereal oil that a kind of mosquito control is bitten, be prepared from (every part of 10g) primarily of following raw materials according: Radix Arnebiae (Radix Lithospermi) 12 parts, Radix Angelicae Sinensis 15 parts, Semen Sapii 12 parts, Cortex Moutan 9 parts, Herba Schizonepetae 9 parts, Fructus Crotonis 10 parts, Zaocys 12 parts, linalool thyme oil is (purchased from Shanghai Po Li trade Co., Ltd, specification 50ml, article No. PET0701), Rhizoma Melaleuca Viridiflora quintessence oil is (purchased from Xu Lan bio tech ltd, Shenzhen, specification 10ml, article No. XLE300), VE(is purchased from Jiahe, the Holy Land, Shandong biological engineering company limited, specification 1000 IU/g), Semen Vitis viniferae quintessence oil is (purchased from Shanghai Hui En International Trading Company Ltd, specification 1000ml, article No. M-00265), tea tree ethereal oil is (purchased from Bao Tianman pharmaceutcal corporation, Ltd of Nan Zhao, specification 30ml, article No. HL015) in right amount each.The preparation method of the compound recipe tea tree ethereal oil that above-mentioned a kind of mosquito control is bitten is:
(1) get Semen Sapii and Fructus Crotonis to clean, add rice vinegar and infiltrate 25 minutes, take out and be placed in frying pan, slow fire heats, and fries to dry, takes out and pulverized 100 mesh sieves;
(2) get Zaocys removing impurity, with water cleaning twice, be cut into strip, be placed in steamer, add yellow wine and steam 35 minutes, take out and pulverize into mud, mix with step (1) gained medicated powder, be added to supercritical CO together 2in extraction equipment, setting extracting pressure is 30MPa, and extraction temperature is 38 DEG C, and resolution temperature is 50 DEG C, extracts 7 hours, terminates rear collection volatile oil;
(3) Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Cortex Moutan and Herba Schizonepetae are cleaned, shave, add the warm water soaking 60 minutes of raw materials quality 6 times, then use volatile oil extractor continuous circumfluence extraction 7 hours, collect volatile oil;
(4) blend step (2) (3) gained volatile oil, make volatile oil A, by volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil, according to the mass ratio of 0.8:0.8:0.6:0.4:1.0, be added to respectively in Semen Vitis viniferae quintessence oil (its quality is 3 times of volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass), stir, leave standstill after 10-16 hour and filter, bottling, obtains compound recipe tea tree ethereal oil.
Typical case: xxx, women, 16 years old, patient lived rural area, was often subject to the harassing and wrecking of mosquito summer, caused sleep bad, and daytime, and after mosquito bite, skin was red and swollen on a large scale, itches very much, once uses essential balm, and effect is bad out of spirits.From this example of use gained compound recipe tea tree ethereal oil, spread upon mosquito bite place, antipruritic very soon, red and swollen basic elimination next day, and there is the effect of pre-mosquito proof, be applied in skin surface, evening, sleep was substantially close without mosquito.
embodiment 3the compound recipe tea tree ethereal oil that a kind of mosquito control is bitten, be prepared from (every part of 10g) primarily of following raw materials according: Radix Arnebiae (Radix Lithospermi) 8 parts, Radix Angelicae Sinensis 11 parts, Semen Sapii 8 parts, Cortex Moutan 5 parts, Herba Schizonepetae 5 parts, Fructus Crotonis 7 parts, Zaocys 9 parts, linalool thyme oil is (purchased from Shanghai Po Li trade Co., Ltd, specification 50ml, article No. PET0701), Rhizoma Melaleuca Viridiflora quintessence oil is (purchased from Xu Lan bio tech ltd, Shenzhen, specification 10ml, article No. XLE300), VE(is purchased from Jiahe, the Holy Land, Shandong biological engineering company limited, specification 1000 IU/g), Semen Vitis viniferae quintessence oil is (purchased from Shanghai Hui En International Trading Company Ltd, specification 1000ml, article No. M-00265), tea tree ethereal oil is (purchased from Bao Tianman pharmaceutcal corporation, Ltd of Nan Zhao, specification 30ml, article No. HL015) in right amount each.The preparation method of the compound recipe tea tree ethereal oil that above-mentioned a kind of mosquito control is bitten is:
(1) get Semen Sapii and Fructus Crotonis to clean, add rice vinegar and infiltrate 18 minutes, take out and be placed in frying pan, slow fire heats, and fries to dry, takes out and pulverized 70 mesh sieves;
(2) get Zaocys removing impurity, with water cleaning twice, be cut into strip, be placed in steamer, add yellow wine and steam 25 minutes, take out and pulverize into mud, mix with step (1) gained medicated powder, be added to supercritical CO together 2in extraction equipment, setting extracting pressure is 30MPa, and extraction temperature is 38 DEG C, and resolution temperature is 50 DEG C, extracts 5 hours, terminates rear collection volatile oil;
(3) Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Cortex Moutan and Herba Schizonepetae are cleaned, shave, add the warm water soaking 45 minutes of raw materials quality 4.5 times, then use volatile oil extractor continuous circumfluence extraction 5.5 hours, collect volatile oil;
(4) blend step (2) (3) gained volatile oil, make volatile oil A, by volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil, according to the mass ratio of 0.8:0.8:0.6:0.4:1.0, be added to respectively in Semen Vitis viniferae quintessence oil (its quality is 2 times of volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass), stir, leave standstill after 10-16 hour and filter, bottling, obtains compound recipe tea tree ethereal oil.
embodiment 4the compound recipe tea tree ethereal oil that a kind of mosquito control is bitten, be prepared from (every part of 10g) primarily of following raw materials according: Radix Arnebiae (Radix Lithospermi) 10 parts, Radix Angelicae Sinensis 13 parts, Semen Sapii 10 parts, Cortex Moutan 8 parts, Herba Schizonepetae 8 parts, Fructus Crotonis 9 parts, Zaocys 11 parts, linalool thyme oil is (purchased from Shanghai Po Li trade Co., Ltd, specification 50ml, article No. PET0701), Rhizoma Melaleuca Viridiflora quintessence oil is (purchased from Xu Lan bio tech ltd, Shenzhen, specification 10ml, article No. XLE300), VE(is purchased from Jiahe, the Holy Land, Shandong biological engineering company limited, specification 1000 IU/g), Semen Vitis viniferae quintessence oil is (purchased from Shanghai Hui En International Trading Company Ltd, specification 1000ml, article No. M-00265), tea tree ethereal oil is (purchased from Bao Tianman pharmaceutcal corporation, Ltd of Nan Zhao, specification 30ml, article No. HL015) in right amount each.The preparation method of the compound recipe tea tree ethereal oil that above-mentioned a kind of mosquito control is bitten is:
(1) get Semen Sapii and Fructus Crotonis to clean, add rice vinegar and infiltrate 22 minutes, take out and be placed in frying pan, slow fire heats, and fries to dry, takes out and pulverized 90 mesh sieves;
(2) get Zaocys removing impurity, with water cleaning twice, be cut into strip, be placed in steamer, add yellow wine and steam 35 minutes, take out and pulverize into mud, mix with step (1) gained medicated powder, be added to supercritical CO together 2in extraction equipment, setting extracting pressure is 30MPa, and extraction temperature is 38 DEG C, and resolution temperature is 50 DEG C, extracts 6 hours, terminates rear collection volatile oil;
(3) Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Cortex Moutan and Herba Schizonepetae are cleaned, shave, add the warm water soaking 55 minutes of raw materials quality 5.5 times, then use volatile oil extractor continuous circumfluence extraction 6.5 hours, collect volatile oil;
(4) blend step (2) (3) gained volatile oil, make volatile oil A, by volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil, according to the mass ratio of 0.8:0.8:0.6:0.4:1.0, be added to respectively in Semen Vitis viniferae quintessence oil (its quality is 3 times of volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass), stir, leave standstill after 10-16 hour and filter, bottling, obtains compound recipe tea tree ethereal oil.
Typical case: xxx, male, 32 years old.Main suit: patient is outdoor enthusiast, often gos deep into mountain forest, and summer wears the clothes less, and skin is exposed, always by mosquito bite, agonizing.Introduce through friend, use this example gained compound recipe tea tree ethereal oil, be coated with skin surface, repelling effect is remarkable, and by after mosquito bite, after smearing three minutes, pruritus pain relief, just recovers normal next day.
embodiment 5the compound recipe tea tree ethereal oil that a kind of mosquito control is bitten, be prepared from (every part of 10g) primarily of following raw materials according: Radix Arnebiae (Radix Lithospermi) 9 parts, Radix Angelicae Sinensis 12 parts, Semen Sapii 9 parts, Cortex Moutan 6.5 parts, Herba Schizonepetae 6.5 parts, Fructus Crotonis 8 parts, Zaocys 10 parts, linalool thyme oil is (purchased from Shanghai Po Li trade Co., Ltd, specification 50ml, article No. PET0701), Rhizoma Melaleuca Viridiflora quintessence oil is (purchased from Xu Lan bio tech ltd, Shenzhen, specification 10ml, article No. XLE300), VE(is purchased from Jiahe, the Holy Land, Shandong biological engineering company limited, specification 1000 IU/g), Semen Vitis viniferae quintessence oil is (purchased from Shanghai Hui En International Trading Company Ltd, specification 1000ml, article No. M-00265), tea tree ethereal oil is (purchased from Bao Tianman pharmaceutcal corporation, Ltd of Nan Zhao, specification 30ml, article No. HL015) in right amount each.The preparation method of the compound recipe tea tree ethereal oil that above-mentioned a kind of mosquito control is bitten is:
(1) get Semen Sapii and Fructus Crotonis to clean, add rice vinegar and infiltrate 20 minutes, take out and be placed in frying pan, slow fire heats, and fries to dry, takes out and pulverized 80 mesh sieves;
(2) get Zaocys removing impurity, with water cleaning twice, be cut into strip, be placed in steamer, add yellow wine and steam 30 minutes, take out and pulverize into mud, mix with step (1) gained medicated powder, be added to supercritical CO together 2in extraction equipment, setting extracting pressure is 30MPa, and extraction temperature is 38 DEG C, and resolution temperature is 50 DEG C, extracts 5.5 hours, terminates rear collection volatile oil;
(3) Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Cortex Moutan and Herba Schizonepetae are cleaned, shave, add the warm water soaking 50 minutes of raw materials quality 5 times, then use volatile oil extractor continuous circumfluence extraction 6 hours, collect volatile oil;
(4) blend step (2) (3) gained volatile oil, make volatile oil A, by volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil, according to the mass ratio of 0.8:0.8:0.6:0.4:1.0, be added to respectively in Semen Vitis viniferae quintessence oil (its quality is 2.5 times of volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass), stir, leave standstill after 10-16 hour and filter, bottling, obtains compound recipe tea tree ethereal oil.
The pharmacology of the present invention's primary raw material used is as follows:
Radix Arnebiae (Radix Lithospermi): base is former: be the root of comfrey Radix Arnebiae (Radix Lithospermi), the false Radix Arnebiae (Radix Lithospermi) in Xinjiang-Tibet or Onosma paniculatum.Chemical analysis: Radix Arnebiae (Radix Lithospermi) contains Acetyl-shikonin Acetylshikonin, isobutyryl shikonin, β, beta-dimethyl-propylene shikonin, β-Hydroxyisovalerylshikonin, 3,4-dimethyl pentene-3-acyl group shikonins.Nature and flavor: bitter, cold.Gui Jing: enter percardium, Liver Channel.Function cures mainly: removing heat from blood, invigorates blood circulation, heat clearing away, removing toxic substances.Control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.
Radix Angelicae Sinensis: nature and flavor with return through sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Semen Sapii: base is former: be the seed of euphorbia plant Cortex Sapii Radicis.Chemical analysis: the fatty oil of seed coat; Ripe seed is containing lipid.Nature and flavor: sweet; Cool; Poisonous.Gui Jing: kidney; Lung meridian.Function cures mainly: detumescence of drawing out pus by applying a plaster to the affected part; Killing parasites for relieving itching.Main eczema; Tinea skin ulcer; Chapped skin; Edema; Constipation.
Cortex Moutan: base is former: be the root bark of ranunculaceae peony.Chemical analysis: root is containing paeonol, paeonolide, paeonolide, paeoniflorin.Still containing volatile oil 0.15 ~ 0.4% and plant sterol etc.Nature and flavor: arduous, cool.Gui Jing: enter the heart, liver, kidney channel.Function cures mainly: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea, lump in the abdomen, and carbuncle and ulcer, flutters damage.
Herba Schizonepetae: base is former: be the herb of labiate Herba Schizonepetae.Acrid in the mouth, slightly warm in nature.Have the loose wind that induces sweat, rash, the effect of the skin ulcer that disappears, for flu, headache, measles, rubella, skin infection from the beginning of.
Fructus Crotonis: base is former: be the seed of euphorbia plant Fructus Crotonis.Chemical analysis: containing Oleum Tiglii, wherein has the glyceride of oleic acid, linoleic acid, crotonic acid, tiglic acid etc.; Still containing crotonoside.Nature and flavor: pungent, heat, poisonous.Gui Jing: enter stomach, large intestine channel.Function cures mainly: rush down cold long-pending, orifice opening, by expectorant, and row water, parasite killing.Control cold long-pending sluggish, distension and fullness of the chest and abdomen shoot, abdominal mass due to blood stasis, accumulation of phlegm in the hypochondrium, dysentery, edema, acute throat trouble is controlled in external, sore throat, malignant boil scabies.
Zaocys: base is former: be the entirety of Colubridae animal Zaocys removing internal organs.Nature and flavor: Gan Xian are flat.Gui Jing: " Thunder God concocts property of medicine solution ": " enter lung, spleen two warp." function cures mainly: wind-damp dispelling, the meridian dredging.Dispelling the wind and dampness pathogens insensitive impediment, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.
Linalool thyme oil: from its flower of distillation and leaf, also somewhat green in moderate yellowish-brown, fragrance has strong medical herbs and Oleum Pini taste, function: 1. improve digestive system and gynaecopathia, blood circulation promoting, enhancing immunity, alleviate neuropathic pain, antibacterial.2. wound healing is helped, treatment eczema and pimples skin quality.Activating brain cell, promotes memory and attention, resists dejected and consoles emotional trauma.3. dandruff and suppression are shaved one's head very effective.Antibacterial, spasmolytic, anti-insecticide venom, sterilize, keep fit, shortly to scab.Nightmare is made in the neural prevention of strengthening.
Rhizoma Melaleuca Viridiflora quintessence oil: be raw material with tender leaf and twig, adopts vapor distillation method to extract.Main component is eucalyptole, dipentene or terpinene, limonene, phellandrene, sobrerone or pinene, linalool and menthone.Melaleuca oil can clean slight wound and burn, not chafe; Be again good antibacterial, be therefore also very applicable to the dermatosiss such as Acne treatment.Can be used for the ulcer of skin, wound, can wound healing be promoted; Bergamot Mint Extract, improves the fat secretion amount of oiliness skin and oiliness scalp, can improve comedo and slow down the situation of the dandruff.There is the effect of excitation, can clear the head, focus one's attention on.Famous with antimicrbial power, very helpful to the infectious disease of aspect, thoracic cavity.
VE: full name is vitamin E; it is a kind of fatsoluble vitamin; can be used as antioxidant; vitamin e help prevent polybasic unsaturated fatty acid and phospholipid oxidized, the not oxidated destruction of vitamin A can be protected, and strengthen its effect; lipid peroxide in anti-Hemostatic Oral Liquid increases; prevent the effect of the excessive coagulation of platelet, promote erythrocyte film and stabilize and erythrocytic synthesis, also can reduce the deposition of senile plaque.
Semen Vitis viniferae quintessence oil: seed of Fructus Vitis viniferae forms via five-star mode of colding pressing is refining, in beautiful and natural faint yellow or light green.The Main Ingredients and Appearance of Semen Vitis viniferae quintessence oil is linoleic acid and procyanidin, also containing vitamin B1, B3, B5, and VF, VC, chlorophyll, trace quantity mineral substance element, essential fatty acid, fructose, glucose, mineral, potassium, phosphorus, calcium, magnesium and grape polyphenols.Pharmacological action: reduce Blood Cholesterol, prevent thrombosis, blood vessel dilating effect, there is the effect of nourishing brain cell, regulating plant nerve simultaneously, effectively prevent the various diseases that cardiovascula sclerosis causes.
Tea tree ethereal oil: the quintessence oil extracted through vapor distillation with Camellia sinensis branch and leaf, in colourless or weak yellow liquid.Effect: antibacterial effect is strong, can do the cleaning agent of skin of oiliness skin, acne, can improve comedo, improve scalp health problem; There is the function of killing mycete, the fungal infection such as tinea circinata and tinea pedis disease can be resisted, control candidiasis number, reduce the splitting degree of bacterial strain; Immune ability can also be promoted, help to fully recover after being ill, also can resist acute cheilitis, herpes zoster or chickenpox.
test example 1the test of pesticide effectiveness of the compound recipe tea tree ethereal oil (embodiment 5) that a kind of mosquito control of gained of the present invention is bitten:
1. repelling effect test:
Choose object: the field-collected strains Culex quinquefasciatus worm adopting collection in worksite, measures after 2-3 days in laboratory rearing emergence;
Test method: random selecting 200 mosquitoes, puts into the mosquito cage that length, width and height are 40cm, chooses 8 experimenters, wherein male 4 example, women 4 example, and the compound recipe tea tree ethereal oil selecting a hands to smear a kind of mosquito control of gained of the present invention to bite, as experimental group; Another hands is as blank group.After smearing two hours, hands is put into mosquito cage 2 minutes, observe and whether have mosquito to suck blood, measure once per half an hour later, until when the hands being coated with quintessence oil has a mosquito bite, stop observing, terminate test, record effective protecting time.
Test result: the effective protecting time of 8 experimenters is respectively: 5,6,5,4,4.5,6,5.5,4 hours; learn as calculated; the compound recipe tea tree ethereal oil that a kind of mosquito control of gained of the present invention is bitten; average effective guard time can reach 5 hours, illustrates that products obtained therefrom repelling effect of the present invention is remarkable.
2. therapeutic effect test:
Choose 184 routine mosquito bite patients, wherein male 91 example, women 93 example, age 5-60 year, 34.8 years old mean age, patient is divided at random two groups, experimental group 104 example, matched group 80 example, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.The compound recipe tea tree ethereal oil that experimental group uses a kind of mosquito control of this example gained to bite, is applied in affected part, massages gently; Matched group uses other conventional medicines (essential balm, floral water, dermatitis equality).
Curative effect determinate standard: cure: use after one day, redness is itched and is bitterly disappeared, and skin recovers normal, without other uncomfortable diseases; Effective: redness is itched and bitterly alleviated to some extent, without other uncomfortable diseases; Invalid: without improving before and after using.
Therapeutic outcome is as shown in table 1:
As shown in Table 1, the total effective rate of experimental group reaches 99.0%, is significantly higher than 86.3% of matched group, and illustrate that product of the present invention has good therapeutic effect to mosquito bite, treatment time is short, without other untoward reaction.
The raw material used in the present invention, Radix Arnebiae (Radix Lithospermi) can removing pathogenic heat from blood and toxic substance from the body, Radix Angelicae Sinensis can be enriched blood and be invigorated blood circulation, and Semen Sapii can be drawn out pus by applying a plaster to the affected part detumescence, and Cortex Moutan can clearing away heat and cooling blood, Herba Schizonepetae can be induced sweat loose wind, Fructus Crotonis can parasite killing sensible, Zaocys can dispelling wind and removing obstruction in the collateral, multiple medical material synergism, add auxiliary effect of linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE, Semen Vitis viniferae quintessence oil and tea tree ethereal oil, can effectively bite by mosquito control.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. the compound recipe tea tree ethereal oil bitten of mosquito control, is characterized in that, take off the primary raw material stating quality proportioning and be prepared from: Radix Arnebiae (Radix Lithospermi) 6-12; Radix Angelicae Sinensis 9-15; Semen Sapii 6-12; Cortex Moutan 4-9; Herba Schizonepetae 4-9; Fructus Crotonis 6-10; Zaocys 8-12; Linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE, Semen Vitis viniferae quintessence oil, tea tree ethereal oil are in right amount each.
2. the compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 1, is characterized in that, Radix Arnebiae (Radix Lithospermi) 8-10; Radix Angelicae Sinensis 11-13; Semen Sapii 8-10; Cortex Moutan 5-8; Herba Schizonepetae 5-8; Fructus Crotonis 7-9; Zaocys 9-11; Linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE, Semen Vitis viniferae quintessence oil, tea tree ethereal oil are in right amount each.
3. the compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 1, is characterized in that, Radix Arnebiae (Radix Lithospermi) 9; Radix Angelicae Sinensis 12; Semen Sapii 9; Cortex Moutan 6.5; Herba Schizonepetae 6.5; Fructus Crotonis 8; Zaocys 10; Linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE, Semen Vitis viniferae quintessence oil, tea tree ethereal oil are in right amount each.
4. the preparation method of the compound recipe tea tree ethereal oil that a kind of mosquito control as described in as arbitrary in claim 1-3 is bitten, it is characterized in that, step is as follows:
(1) get Semen Sapii and Fructus Crotonis to clean, adding rice vinegar, to infiltrate 15-25 minute (preferred: to infiltrate 18-22 minute; Be more preferably: infiltrate 20 minutes), take out and be placed in frying pan, slow fire heats, and fry to dry, taking-up pulverizes and sieves;
(2) get Zaocys removing impurity, with water cleaning twice, be cut into strip, be placed in steamer, add yellow wine and steam 25-35 minute (preferred: to add yellow wine and steam 30 minutes), take out and pulverize into mud, mix with step (1) gained medicated powder, be added to supercritical CO together 2in extraction equipment, setting extracting pressure is 30MPa, and extraction temperature is 38 DEG C, and resolution temperature is 50 DEG C, and extraction terminates rear collection volatile oil;
(3) Radix Arnebiae (Radix Lithospermi), Radix Angelicae Sinensis, Cortex Moutan and Herba Schizonepetae are cleaned, shave, add warm water soaking 40-60 minute (preferably: soak 45-55 minute; Be more preferably: soak 50 minutes), then use volatile oil extractor continuous circumfluence extraction, collect volatile oil;
(4) blend step (2) (3) gained volatile oil, makes volatile oil A, by volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil, be added to respectively in Semen Vitis viniferae quintessence oil, stir, leave standstill after 10-16 hour and filter, bottling, obtains compound recipe tea tree ethereal oil.
5. the preparation method of compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 4, it is characterized in that, it is (preferred: to pulverize 70-90 mesh sieve that step (1) pulverized 60-100 mesh sieve; Be more preferably: pulverized 80 mesh sieves).
6. the preparation method of compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 4, is characterized in that, step (2) extraction time be 4-7 hour (preferred: extraction time is 5-6 hour; Be more preferably: extraction time is 5.5 hours).
7. the preparation method of compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 4, is characterized in that, the amount that step (3) adds warm water be the 4-6 of raw materials quality doubly (preferred: the amount adding warm water be the 4.5-5.5 of raw materials quality doubly; Be more preferably: the amount adding warm water is 5 times of raw materials quality).
8. the preparation method of compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 4, it is characterized in that, step (3) continuous circumfluence extraction 5-7 hour is (preferred: continuous circumfluence extraction 5.5-6.5 hour; Be more preferably: continuous circumfluence extraction 6 hours).
9. the preparation method of compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 4, it is characterized in that, the mass ratio of step (4) volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil is 0.8:0.8:0.6:0.4:1.0.
10. the preparation method of compound recipe tea tree ethereal oil bitten of a kind of mosquito control as claimed in claim 4, it is characterized in that, the quality of step (4) Semen Vitis viniferae quintessence oil is volatile oil A, the 2-3 of linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass doubly (preferred: the quality of Semen Vitis viniferae quintessence oil is 2.5 times of volatile oil A, linalool thyme oil, Rhizoma Melaleuca Viridiflora quintessence oil, VE and tea tree ethereal oil gross mass).
CN201510161375.0A 2015-04-07 2015-04-07 Compound tea tree essential oil for preventing and treating mosquito bite Pending CN104706840A (en)

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CN105327079A (en) * 2015-10-23 2016-02-17 华润三九医药股份有限公司 Composition with repairing effect on mosquito bite and application thereof
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CN113717791A (en) * 2021-09-30 2021-11-30 梵申兰科技(上海)有限公司 White tea essential oil for treating tinea pedis and dandruff and application thereof

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