CN104689216A - Medicine for treating chronic nephritis - Google Patents
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Abstract
The invention discloses medicine with traditional Chinese medicine as raw materials for treating chronic nephritis, and belongs to the technical field of traditional Chinese medicine. The medicine is composed of angelica sinensis, atractylodes macrocephala koidz, astragalus, poria cocos, Chinese yam, achyranthes bidentata, semen plantaginis, spreading hedyotis herbs, indian iphigenia bulbs, diversifolious patrinia roots, honeysuckle, euphorbia humifusa, herba artemisiae scopariae, polygonum cuspidatum, red peony roots, ramulus euonyrni, fructus lycii, cornus officinalis, cassia twigs, nutmeg, fructus amomi and semen cassia according to a certain weight proportion. The medicine herbs are used jointly and have the functions of rising yang, tonifying spleen, tonifying the kidney, resolving dampness, inducing diuresis to alleviate edema and nourishing liver and kidney, the medicine functions achieve a synergistic effect, lasting drug efficacy continuously acts on a focus, and the medicine has excellent treatment effect on chronic nephritis.
Description
Technical field
The present invention relates to a kind of medicine be made up of pure raw material of Chinese medicine, specifically a kind of medicine for the treatment of chronic nephritis, belongs to technical field of Chinese medicines.
Background technology
Chronic glomerulonephritis is called for short chronic nephritis, mean that albuminuria, hematuria, hypertension, edema are basic clinical, mode of onset is had nothing in common with each other, protracted inflammation; pathological changes is slowly in progress; can have renal hypofunction in various degree, has renal function exacerbation tendency and the one group of glomerulopathy developing into chronic renal failure the most at last.Due to histological type and the stadium difference of this group disease, main clinical manifestation is different, and disease indicia is in variation.Chronic nephritis can betide any age, but based on Yong adult, male is common.Current doctor trained in Western medicine mainly adopts hormonotherapy or Immunosuppressive therapy to chronic nephritis, and it is strong to the dependency of medicine, and side effect is large, and treatment cost is high.The traditional Chinese medical science has the effect of its uniqueness in the treatment of chronic nephritis, and thus market exists the Chinese medicine for the treatment of chronic nephritis of all kinds, but their therapeutic effect is generally undesirable, treatment cycle is longer, easily recurs.
Summary of the invention
For problems of the prior art, the invention provides a kind of curative effect high, instant effect, do not recur more, the medicine of the treatment chronic nephritis of short treating period.
The present invention is by the following technical solutions:
A kind of medicine for the treatment of chronic nephritis, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Astragali 5-15 part, Poria 20-30 part, Rhizoma Dioscoreae 10-20 part, Radix Achyranthis Bidentatae 8-14 part, Semen Plantaginis 10-20 part, Herba Hedyotidis Diffusae 5-15 part, Pseudobulbus Cremastrae Seu Pleiones 10-20 part, Radix Patriniae heterophyllae 5-15 part, Flos Lonicerae 10-20 part, Herba Euphorbiae Humifusae 10-20 part, Herba Artemisiae Scopariae 4-12 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Paeoniae Rubra 5-15 part, Ramulus Euonymi 4-12 part, Fructus Lycii 10-20 part, Fructus Corni 10-20 part, Ramulus Cinnamomi 5-15 part, Semen Myristicae 8-16 part, Fructus Amomi 6-12 part, Semen Cassiae 5-15 part.
Preferably, the medicine of described treatment chronic nephritis is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Astragali 10 parts, 25 parts, Poria, Rhizoma Dioscoreae 15 parts, Radix Achyranthis Bidentatae 12 parts, Semen Plantaginis 15 parts, Herba Hedyotidis Diffusae 10 parts, Pseudobulbus Cremastrae Seu Pleiones 15 parts, Radix Patriniae heterophyllae 10 parts, Flos Lonicerae 15 parts, Herba Euphorbiae Humifusae 15 parts, Herba Artemisiae Scopariae 8 parts, Rhizoma Polygoni Cuspidati 15 parts, Radix Paeoniae Rubra 10 parts, Ramulus Euonymi 10 parts, Fructus Lycii 15 parts, Fructus Corni 15 parts, Ramulus Cinnamomi 10 parts, Semen Myristicae 12 parts, Fructus Amomi 8 parts, Semen Cassiae 10 parts.
The pharmacological action of formulation of drug of the present invention is as follows:
Radix Angelicae Sinensis: sweet, pungent, warm; Return liver, the heart, spleen channel; Having enriches blood invigorates blood circulation, and menstruction regulating and pain relieving moisturizes effect of laxation.The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm; Return spleen, stomach warp; There is invigorating the spleen and benefiting QI, dampness diuretic, effect that hidroschesis is antiabortive.The Radix Astragali: sweet, tepor; Return lung, spleen, liver, kidney channel; There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation.Poria: sweet, light is flat; GUIXIN, lung, spleen, kidney channel; There is promoting diuresis to eliminate damp pathogen, effect of spleen invigorating mind calming.Rhizoma Dioscoreae: sweet, flat, nontoxic; Return spleen, lung, kidney channel; There is nourishing strong, aid digestion, hold back sweating due to debility, effect of antidiarrheal.Radix Achyranthis Bidentatae: picric acid is flat; Enter the heart, liver, large intestine three warp; There is promoting blood circulation to remove blood stasis, damp eliminating diuresis, effect of heat-clearing and toxic substances removing.Semen Plantaginis: sweet, cold; Return liver, kidney, lung, small intestine meridian; There is clearing away heat and promoting diuresis treating stranguria, eliminating dampness by diuresis antidiarrheal, effect that improving eyesight is eliminated the phlegm.Herba Hedyotidis Diffusae: micro-hardship, cold; Return stomach, large intestine, small intestine meridian; There is heat-clearing and toxic substances removing, effect that dampness removing is treating stranguria.Pseudobulbus Cremastrae Seu Pleiones: sweet, micro-pungent, cold in nature; Return liver, stomach, spleen channel; There is heat-clearing and toxic substances removing, effect of eliminating carbuncle eliminating stagnation.Radix Patriniae heterophyllae: bitter, micro-acid, puckery, cool; Enter the heart, liver two warp; There is heat clearing and damp drying, hemostasis, leukorrhagia stopping, effect of preventing the attack (or recurrence) of malaria.Flos Lonicerae: cold, sweet; Attach to the lung and stomach meridians; There is heat-clearing and toxic substances removing, effect of dispelling wind and heat pathogens.Herba Euphorbiae Humifusae: pungent, bitter, flat; Return liver, stomach, large intestine channel; There is promoting blood circulation and hemostasis, clearing away heat-damp and promoting diuresis, effect of removing toxic substances and promoting subsidence of swelling.Herba Artemisiae Scopariae: bitter, pungent, is slightly cold; Return spleen, stomach, liver, gallbladder meridian; There is eliminating damp-heat, effect of promoting the function of the gallbladder to alleviate jaundice.Rhizoma Polygoni Cuspidati: micro-hardship, is slightly cold; Return liver, gallbladder, lung meridian; There is dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, effect of relieving cough and resolving phlegm.Radix Paeoniae Rubra: bitter, is slightly cold; Return liver, spleen channel; There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.Ramulus Euonymi: bitter, cold; Return meridian of Foot-JUE YIN; There is blood circulation promoting and blood stasis dispelling, effect of dredge the meridian passage.Fructus Lycii: sweet is flat; Return liver, kidney channel; There is nourishing the liver and kidney, effect of replenishing vital essence to improve eyesight.Fructus Corni: sour, puckery, tepor; Return liver, kidney channel; There is liver and kidney tonifying, effect of arresting collape syndrome by astringents.Ramulus Cinnamomi: acrid, sweet, warm; Return lung, the heart, urinary bladder channel; There is relieving the exterior syndrome by diaphoresis, dispersing cold for relieving pain, effect of activating YANG and prormoting functioning of QI.Semen Myristicae: pungent, temperature; Return spleen, stomach, large intestine channel; There is warming middle-JIAO to promote flow of QI, effect of relieving diarrhea with astringents.Fructus Amomi: pungent is wet; Return spleen, stomach, kidney channel; Removing dampness is had to whet the appetite, warming spleen and stopping diarrha, antiabortive effect of regulating the flow of vital energy.Semen Cassiae: bitter, sweet, salty, is slightly cold; Enter liver, kidney, large intestine channel; There is loosening bowel to relieve constipation, effect of blood fat reducing improving eyesight.
The traditional Chinese medical science thinks that the generation of chronic nephritis is all relevant with vital QI being weakened and pathogen being violent with development, and weakened body resistance is this, and the domination of pathogen is mark, is a kind of disease of simulataneous insufficiency and excessive.Weakened body resistancely be mainly manifested in lung, spleen, kidney three are dirty, wherein the most common with deficiency of spleen and stomach; The domination of pathogen is mainly based on wet, heat, the stasis of blood, poison.Medicine of the present invention carries out dialectical treatment according to the characteristics of incidence of chronic nephritis, to lung, spleen, the dirty common conditioning of kidney three, makes it thoroughly be effected a radical cure.In the present invention, all medicines share, and have effect of yang invigorating spleen reinforcing, kidney tonifying removing dampness, inducing diuresis to remove edema, nourishing the liver and kidney, its drug effect synergism, and the lasting efficacy of a drug acts on focus continuously, reaches the effect for the treatment of both the principal and secondary aspects of a disease.
The preparation method of medicine of the present invention is:
(1) take above-mentioned formula ratio material medicine according to quantity, after adding 800-1000ml cold water soak 1.5-2 hour wherein, first to burn to boiling slow fire boiling again 25 minutes with intense fire, filter to obtain a filtered juice;
(2) continuing to add water 800ml decoction to seething with excitement latter 15 minutes in filtering residue, filtering to obtain secondary filtered juice;
(3) first and second filtered juice merged, heating is concentrated into 400ml.
The usage of medicine of the present invention and consumption: decocting is oral, a side is potion, potion on the one, one day twice, respectively at sooner or later respectively taking 200ml half an hour after meal.Within 10 days, be 1 course for the treatment of, general 3-5 can cure a course for the treatment of.
The invention has the beneficial effects as follows: pharmaceutical formulation of the present invention is scientific and reasonable, all medicine Synergistics, have curative effect to the treatment of chronic nephritis high, short treating period, does not recur, and cost is low, the feature of safe without toxic side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1
Treat a medicine for chronic nephritis, it is made up of the crude drug of following weight: Radix Angelicae Sinensis 10g, Rhizoma Atractylodis Macrocephalae 10g, Radix Astragali 5g, Poria 20g, Rhizoma Dioscoreae 10g, Radix Achyranthis Bidentatae 8g, Semen Plantaginis 10g, Herba Hedyotidis Diffusae 5g, Pseudobulbus Cremastrae Seu Pleiones 10g, Radix Patriniae heterophyllae 5g, Flos Lonicerae 10g, Herba Euphorbiae Humifusae 10g, Herba Artemisiae Scopariae 4g, Rhizoma Polygoni Cuspidati 10g, Radix Paeoniae Rubra 5g, Ramulus Euonymi 4g, Fructus Lycii 10g, Fructus Corni 10g, Ramulus Cinnamomi 5g, Semen Myristicae 8g, Fructus Amomi 6g, Semen Cassiae 5g.
The preparation method of said medicine:
1) take above-mentioned formula ratio material medicine according to quantity, after adding 800-1000ml cold water soak 1.5-2 hour wherein, first to burn to boiling slow fire boiling again 25 minutes with intense fire, filter to obtain a filtered juice;
(2) continuing to add water 800ml decoction to seething with excitement latter 15 minutes in filtering residue, filtering to obtain secondary filtered juice;
(3) first and second filtered juice merged, heating is concentrated into 400ml.
Embodiment 2
Treat a medicine for chronic nephritis, it is made up of the crude drug of following weight: Radix Angelicae Sinensis 15g, Rhizoma Atractylodis Macrocephalae 15g, Radix Astragali 10g, Poria 25g, Rhizoma Dioscoreae 15g, Radix Achyranthis Bidentatae 12g, Semen Plantaginis 15g, Herba Hedyotidis Diffusae 10g, Pseudobulbus Cremastrae Seu Pleiones 15g, Radix Patriniae heterophyllae 10g, Flos Lonicerae 15g, Herba Euphorbiae Humifusae 15g, Herba Artemisiae Scopariae 8g, Rhizoma Polygoni Cuspidati 15g, Radix Paeoniae Rubra 10g, Ramulus Euonymi 10g, Fructus Lycii 15g, Fructus Corni 15g, Ramulus Cinnamomi 10g, Semen Myristicae 12g, Fructus Amomi 8g, Semen Cassiae 10g.
The preparation method of said medicine is with embodiment 1.
Embodiment 3
Treat a medicine for chronic nephritis, it is made up of the crude drug of following weight: Radix Angelicae Sinensis 20g, Rhizoma Atractylodis Macrocephalae 20g, Radix Astragali 15g, Poria 30g, Rhizoma Dioscoreae 20g, Radix Achyranthis Bidentatae 14g, Semen Plantaginis 20g, Herba Hedyotidis Diffusae 15g, Pseudobulbus Cremastrae Seu Pleiones 20g, Radix Patriniae heterophyllae 15g, Flos Lonicerae 20g, Herba Euphorbiae Humifusae 20g, Herba Artemisiae Scopariae 12g, Rhizoma Polygoni Cuspidati 20g, Radix Paeoniae Rubra 15g, Ramulus Euonymi 12g, Fructus Lycii 20g, Fructus Corni 20g, Ramulus Cinnamomi 15g, Semen Myristicae 16g, Fructus Amomi 12g, Semen Cassiae 15g.
The preparation method of said medicine is with embodiment 1.
Embodiment 4
Treat a medicine for chronic nephritis, it is made up of the crude drug of following weight: Radix Angelicae Sinensis 16g, Rhizoma Atractylodis Macrocephalae 15g, Radix Astragali 12g, Poria 22g, Rhizoma Dioscoreae 12g, Radix Achyranthis Bidentatae 12g, Semen Plantaginis 16g, Herba Hedyotidis Diffusae 8g, Pseudobulbus Cremastrae Seu Pleiones 18g, Radix Patriniae heterophyllae 12g, Flos Lonicerae 20g, Herba Euphorbiae Humifusae 14g, Herba Artemisiae Scopariae 6g, Rhizoma Polygoni Cuspidati 15g, Radix Paeoniae Rubra 12g, Ramulus Euonymi 8g, Fructus Lycii 16g, Fructus Corni 15g, Ramulus Cinnamomi 12g, Semen Myristicae 10g, Fructus Amomi 8g, Semen Cassiae 8g.
The preparation method of said medicine is with embodiment 1.
Clinical trial example
1. clinical data: random selecting outpatient service accept for medical treatment patient 340 example, wherein man 189 example, female 151 example, the age 25-60 year.
2. diagnostic criteria: according to there being albuminuria, hematuria (erythrocyte of the common polymorphic change of phase contrast microscope inspection), hypertension, edema, the glomerulonephritis clinical manifestations such as renal insufficiency can be made a definite diagnosis.
3. Therapeutic Method: take medicine of the present invention, decocting is oral, a side is potion, potion on the one, one day twice, respectively at sooner or later respectively taking 200ml half an hour after meal.Within 10 days, be 1 course for the treatment of, general 3-5 can cure a course for the treatment of, and patient with severe symptoms needs 6-7 the course for the treatment of.
4. curative effect determinate standard:
Cure: clinical symptoms all disappears, body constitution recovers normal, follows up a case by regular visits to 1 year without recurrence;
Effective: clinical symptoms is clearly better;
Invalid: clinical symptoms is without significant change or add severe one.
5. therapeutic outcome: in the treatment to 340 routine patients with chronic glomerulonephritis, cures 288 examples, accounts for 84.7%; Effective 51 examples, account for 15%; Invalid 1 example, accounts for 0.3%; Total effective rate reaches 99.7%.
Model case
Case 1: Lee, female, 35 years old, edema of lower limbs 2 months, soreness of the waist and knees, severe albuminuria; Blood pressure 150/95mmHg, clinical diagnosis is chronic nephritis.Through western medical treatment remission but fail radical cure, rear employing Chinese traditional treatment after 2 months, after using 2 courses for the treatment of of medicine of the present invention, patient clinical transference cure is more than half, 2 courses for the treatment of of rear continuation after treatment, and patient fully recovers, and follows up a case by regular visits to and does not recur for 1 year.
Case 2: high certain, man, 45 years old, pharyngalgia, gums abscess, albuminuria was quantitatively 1.5g in 24 hours, and edema that lower limb are slight, blood pressure 160/90mmHg, is diagnosed as chronic nephritis.After patient uses 3 courses for the treatment of of Drug therapy of the present invention, clinical symptoms all disappears, and follows up a case by regular visits to and does not recur for 2 years.
Case 3: Lin, man 28 years old, face and edema of lower limbs, weak lumbago, urine protein is quantitatively 3g in 24 hours, has erythrocyte+1 ~+3 all the time, be diagnosed as chronic nephritis in urine.After using 2 courses for the treatment of of Drug therapy of the present invention, patients symptomatic disappears most, continues to strengthen patient's recovery from illness after 2 courses for the treatment of of treatment, follows up a case by regular visits to 1 year without recurrence.
Claims (2)
1. treat the medicine of chronic nephritis for one kind, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Astragali 5-15 part, Poria 20-30 part, Rhizoma Dioscoreae 10-20 part, Radix Achyranthis Bidentatae 8-14 part, Semen Plantaginis 10-20 part, Herba Hedyotidis Diffusae 5-15 part, Pseudobulbus Cremastrae Seu Pleiones 10-20 part, Radix Patriniae heterophyllae 5-15 part, Flos Lonicerae 10-20 part, Herba Euphorbiae Humifusae 10-20 part, Herba Artemisiae Scopariae 4-12 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Paeoniae Rubra 5-15 part, Ramulus Euonymi 4-12 part, Fructus Lycii 10-20 part, Fructus Corni 10-20 part, Ramulus Cinnamomi 5-15 part, Semen Myristicae 8-16 part, Fructus Amomi 6-12 part, Semen Cassiae 5-15 part.
2. the medicine for the treatment of chronic nephritis according to claim 1, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Astragali 10 parts, 25 parts, Poria, Rhizoma Dioscoreae 15 parts, Radix Achyranthis Bidentatae 12 parts, Semen Plantaginis 15 parts, Herba Hedyotidis Diffusae 10 parts, Pseudobulbus Cremastrae Seu Pleiones 15 parts, Radix Patriniae heterophyllae 10 parts, Flos Lonicerae 15 parts, Herba Euphorbiae Humifusae 15 parts, Herba Artemisiae Scopariae 8 parts, Rhizoma Polygoni Cuspidati 15 parts, Radix Paeoniae Rubra 10 parts, Ramulus Euonymi 10 parts, Fructus Lycii 15 parts, Fructus Corni 15 parts, Ramulus Cinnamomi 10 parts, Semen Myristicae 12 parts, Fructus Amomi 8 parts, Semen Cassiae 10 parts.
Priority Applications (1)
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105616702A (en) * | 2016-02-04 | 2016-06-01 | 青岛市中心医院 | Medicine for preventing and treating chronic glomerulonephritis |
| CN107823484A (en) * | 2017-12-08 | 2018-03-23 | 代哲尘 | A kind of Chinese medicine composition for treating chronic nephritis and preparation method thereof |
| CN108371702A (en) * | 2018-05-08 | 2018-08-07 | 耿全好 | A kind of drug for the liver cell that can repair damage |
| CN108379501A (en) * | 2018-05-11 | 2018-08-10 | 耿全好 | A kind of formula of pure Chinese medicine treatment pneumonia |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104013871A (en) * | 2014-06-30 | 2014-09-03 | 陈玲 | Traditional Chinese medicine composition for treating chronic nephritis |
| CN104288579A (en) * | 2014-10-30 | 2015-01-21 | 崔新明 | Traditional Chinese medicine for treating chronic nephritis and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104013871A (en) * | 2014-06-30 | 2014-09-03 | 陈玲 | Traditional Chinese medicine composition for treating chronic nephritis |
| CN104288579A (en) * | 2014-10-30 | 2015-01-21 | 崔新明 | Traditional Chinese medicine for treating chronic nephritis and preparation method thereof |
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| 闫晓萍主编: "《原发性肾小球肾炎的中西医治疗》", 31 January 2001 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105616702A (en) * | 2016-02-04 | 2016-06-01 | 青岛市中心医院 | Medicine for preventing and treating chronic glomerulonephritis |
| CN107823484A (en) * | 2017-12-08 | 2018-03-23 | 代哲尘 | A kind of Chinese medicine composition for treating chronic nephritis and preparation method thereof |
| CN108371702A (en) * | 2018-05-08 | 2018-08-07 | 耿全好 | A kind of drug for the liver cell that can repair damage |
| CN108379501A (en) * | 2018-05-11 | 2018-08-10 | 耿全好 | A kind of formula of pure Chinese medicine treatment pneumonia |
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| CN104689216B (en) | 2018-02-16 |
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