CN104684558A - 诊断和治疗运动神经元疾病的方法 - Google Patents

诊断和治疗运动神经元疾病的方法 Download PDF

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Publication number
CN104684558A
CN104684558A CN201380051051.0A CN201380051051A CN104684558A CN 104684558 A CN104684558 A CN 104684558A CN 201380051051 A CN201380051051 A CN 201380051051A CN 104684558 A CN104684558 A CN 104684558A
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mir
reagent
mirna
mnd
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Chinese (zh)
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E.霍恩斯泰恩
A.M.伊姆德
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Yeda Research and Development Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201380051051.0A 2012-07-31 2013-07-31 诊断和治疗运动神经元疾病的方法 Pending CN104684558A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261677494P 2012-07-31 2012-07-31
US61/677494 2012-07-31
PCT/IL2013/050655 WO2014020608A1 (en) 2012-07-31 2013-07-31 Methods of diagnosing and treating motor neuron diseases

Publications (1)

Publication Number Publication Date
CN104684558A true CN104684558A (zh) 2015-06-03

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CN201380051051.0A Pending CN104684558A (zh) 2012-07-31 2013-07-31 诊断和治疗运动神经元疾病的方法

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US (1) US10159670B2 (https=)
EP (1) EP2879678B1 (https=)
JP (1) JP6340366B2 (https=)
CN (1) CN104684558A (https=)
HK (1) HK1205453A1 (https=)
WO (1) WO2014020608A1 (https=)

Cited By (1)

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CN105663129A (zh) * 2015-12-29 2016-06-15 山东大学 用于治疗肌萎缩侧索硬化和额颞叶痴呆的化合物与应用

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Cited By (3)

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CN105663129A (zh) * 2015-12-29 2016-06-15 山东大学 用于治疗肌萎缩侧索硬化和额颞叶痴呆的化合物与应用
WO2017113268A1 (zh) * 2015-12-29 2017-07-06 山东大学 用于治疗肌萎缩侧索硬化和额颞叶痴呆的化合物与应用
CN105663129B (zh) * 2015-12-29 2020-05-15 山东大学 用于治疗肌萎缩侧索硬化和额颞叶痴呆的化合物与应用

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US10159670B2 (en) 2018-12-25
HK1205453A1 (en) 2015-12-18
JP6340366B2 (ja) 2018-06-06
JP2015523410A (ja) 2015-08-13
US20150164891A1 (en) 2015-06-18
EP2879678B1 (en) 2023-03-01
EP2879678A1 (en) 2015-06-10
WO2014020608A1 (en) 2014-02-06

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