CN104667202A - Traditional Chinese medicine composition for treating hypertension - Google Patents
Traditional Chinese medicine composition for treating hypertension Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hypertension and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following components according to the weight proportion: semen plantaginis, uncaria, semen boitae, loranthus parasiticus, rhizoma acori graminei, semen cassia, tuber fleeceflower stems, raspberries, lumbricus, schisandra hinensis, lilies, astragalus membranaceus, yam rhizome, cinnamon, scorpio, radix ophiopogonis, pollen typhae, aster, curcuma zedoary, notopterygium roots, caulis spatholobi, jasmine and thunberg fritillary bulbs. The traditional Chinese medicine composition prepared has the functions of promoting blood circulation to remove blood stasis, dispelling wind and removing obstruction in the meridians, tranquilize mind by nourishing the heart, clearing away heat and toxic materials and nourishment for vitality and has the advantages of high curative effect, short course of treatment, quick response, low cost and no side effects for treating hypertension.
Description
Technical field
The present invention relates to one and treat hypertensive Chinese medicine composition, belong to technical field of Chinese medicines.
Background technology
Hypertension is common clinical, frequently-occurring disease, and be one of cardiovascular disease common in the world today, sickness rate cumulative year after year, the trend in rejuvenation, the health of the people in serious threat.The whole world about 30% people dies from cardiocerebrovasculaevents events, wherein has the apoplexy event of 62% and the cardiovascular event of 49% to be directly caused by hypertension.Clinical in hypertensive treatment, people widely use various Western medicine depressor, as the medicine of diuretic, beta-blocker, angiotensin I-converting enzyme inhibitor, calcium antagonist, sympathetic inhibitor and vasoactive smooth muscle, these antihypertensive drugs need long-term taking, human body easily produces drug resistance and has larger side effect to human body, and they can only take stopgap measures, can not effect a permanent cure.Chinese and Western medicine is compared, and side effect is obviously little, and curative effect is lasting, and effect relaxes.Also there are some in the market and treat hypertensive Chinese medicine, but its therapeutic effect is unsatisfactory.
Summary of the invention
For problems of the prior art, the invention provides one and treat hypertensive Chinese medicine composition.This medicine is formed by pure prepared from traditional Chinese medicines, and determined curative effect has a lasting medicinal property, and curative effect is high, and instant effect does not recur more, and cost is low, and safety has no side effect.
The present invention is by the following technical solutions:
One treats hypertensive Chinese medicine composition, it is characterized in that, it is made up of the crude drug of following weight portion: Semen Plantaginis 4-8 part, Ramulus Uncariae Cum Uncis 10-20 part, Semen Platycladi 5-15 part, Herba Taxilli 5-15 part, Rhizoma Acori Graminei 8-16 part, Semen Cassiae 20-30 part, Caulis Polygoni Multiflori 10-20 part, Fructus Rubi 5-15 part, Pheretima 10-16 part, Fructus Schisandrae Chinensis 15-25 part, Bulbus Lilii 15-25 part, Radix Astragali 20-30 part, Rhizoma Dioscoreae Septemlobae 12-18 part, Cortex Cinnamomi 6-12 part, Scorpio 10-20 part, Radix Ophiopogonis 12-16 part, Pollen Typhae 4-10 part, Radix Asteris 3-8 part, Rhizoma Curcumae 10-20 part, Rhizoma Et Radix Notopterygii 20-40 part, Caulis Spatholobi 15-25 part, SHANZHIZI 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part.
Preferably, the hypertensive Chinese medicine composition of described treatment is made up of the crude drug of following weight portion: Semen Plantaginis 6 parts, Ramulus Uncariae Cum Uncis 15 parts, Semen Platycladi 10 parts, Herba Taxilli 10 parts, Rhizoma Acori Graminei 14 parts, Semen Cassiae 25 parts, Caulis Polygoni Multiflori 15 parts, Fructus Rubi 10 parts, Pheretima 13 parts, Fructus Schisandrae Chinensis 20 parts, Bulbus Lilii 20 parts, the Radix Astragali 25 parts of, Rhizoma Dioscoreae Septemlobae 16 parts, Cortex Cinnamomi 10 parts, Scorpio 15 parts, Radix Ophiopogonis 14 parts, Pollen Typhae 8 parts, Radix Asteris 5 parts, Rhizoma Curcumae 15 parts, Rhizoma Et Radix Notopterygii 30 parts, Caulis Spatholobi 20 parts, SHANZHIZI 15 parts, Bulbus Fritillariae Thunbergii 15 parts.
The preparation method of medicine of the present invention is as follows: take formula ratio material medicine according to quantity, adds 1000ml cold water soak wherein after 1 hour, first to burn to boiling slow fire boiling again 30 minutes with intense fire, filters to obtain a filtered juice; Continuing to add water 600ml decoction to seething with excitement latter 20 minutes in filtering residue, filtering to obtain secondary filtered juice; First and second filtered juice is merged centrifugalize or sedimentation filtration, then concentrated, dry, add after customary adjuvant makes granule sterilization and incapsulate, every heavy 0.5g.
Usage and consumption: oral, every day 3 times, one time 2, within 7 days, be a course for the treatment of, general 1 course for the treatment of can take effect, and 2-4 the course for the treatment of can cure.
Pharmacological action of the present invention is as follows:
Semen Plantaginis: sweet, cold; Return liver, kidney, lung, small intestine meridian; There is clearing away heat and promoting diuresis treating stranguria, eliminating dampness by diuresis antidiarrheal, effect that improving eyesight is eliminated the phlegm.
Ramulus Uncariae Cum Uncis: sweet is cool; Return liver, pericardium channel; There is heat clearing away suppressing the hyperactive liver, effect of dispelling wind and relieving convulsion.
Semen Platycladi: sweet is flat; GUIXIN, kidney, large intestine channel; There is tranquilizing by nourishing the heart, loosening bowel to relieve constipation, effect of hidroschesis.
Herba Taxilli: bitter, sweet, flat; Return liver, kidney channel; There is wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, effect of antiabortive unit.
Rhizoma Acori Graminei: pungent, bitter, tepor; GUIXIN, liver, spleen channel; There is waking up the patient from unconsciousness by dissipating phlegm, removing dampness circulation of qi promoting, effect of dispel the wind sharp numbness, reducing swelling and alleviating pain.
Semen Cassiae: sweet, bitter, salty, is slightly cold; Return liver, large intestine channel; There is clearing away heat to improve acuity of vision, effect of loosening bowel to relieve constipation.
Caulis Polygoni Multiflori: sweet, micro-hardship is flat; Enter the heart, Liver Channel; There is tranquilizing by nourishing the heart, effect that dredging collateral dispels the wind.
Fructus Rubi: sweet, sour, temperature; Return kidney, urinary bladder channel; There is kidney tonifying, controlling nocturnal emission with astringent drugs, effect of reducing urination.
Pheretima: salty, cold; Return liver, spleen, urinary bladder channel; Have heat clearing away arresting convulsion, dredging collateral, relievings asthma, effect of diuresis.
Fructus Schisandrae Chinensis: sour, sweet, temperature; Return lung, the heart, kidney channel; There is convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, effect of kidney calming.
Bulbus Lilii: sweet, cold; GUIXIN, lung meridian; There is nourishing YIN and moistening the lung, effect of clearing away heart-fire for tranquillization.
The Radix Astragali: sweet, temperature; Return lung, spleen channel; There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, effect of expelling pus and promoting granulation.
Rhizoma Dioscoreae Septemlobae: bitter is flat; Return kidney, stomach warp; Having dampness removing goes turbid, effect of wind expelling stagnation removing.
Cortex Cinnamomi: pungent, sweet, hot greatly; Return kidney, spleen, the heart, Liver Channel; There is benefit fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, effect of promoting blood circulation to restore menstrual flow.
Scorpio: pungent, flat; Poisonous; Return Liver Channel; There is endogenous wind stopping spasmolytic, dispersing pathogen accumulation, effect of removing obstruction in the collateral to relieve pain.
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold; GUIXIN, lung, stomach warp; There is YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire.
Pollen Typhae: sweet, flat; Return liver, pericardium channel; There is hemostasis, blood stasis dispelling, treating stranguria effect.
Radix Asteris: bitter, temperature; Return lung meridian; There is dissipating phlegm and keeping the adverse QI downwards, lung heat clearing expel the heat-evil, effect of regulating fluid apssage.
Rhizoma Curcumae: pungent, bitter, temperature; Return liver, spleen channel; There is circulation of qi promoting removing blood stasis, effect of removing food stagnancy pain relieving.
Rhizoma Et Radix Notopterygii: pungent, bitter, temperature; Enter bladder, kidney channel; There is the cold expelling that induces sweat, expelling wind and dampness, effect of pain relieving.
Caulis Spatholobi: bitter, sweet, temperature; Return liver, kidney channel; There is blood circulation promoting and enriching, menstruction regulating and pain relieving, effect of relaxing muscles and tendons and activating QI and blood in the collateral.
SHANZHIZI: bitter, cold; GUIXIN, lung, tri-jiao channel; There is pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, effect of removing pathogenic heat from blood and toxic substance from the body.
Bulbus Fritillariae Thunbergii: bitter, cold; Return lung, heart channel; There is clearing heat, eliminating phlegm, relieving cough, effect of detoxicating and resolving stagnation of pathogens eliminating carbuncle.
The invention has the beneficial effects as follows: pharmaceutical formulation of the present invention is scientific and reasonable, its drug effect has synergism, have blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, tranquilizing by nourishing the heart, heat-clearing and toxic substances removing, nourishing YIN and invigorating YANG, effect, pass through conditioning viscera, recover equilibrium between yin and yang, the QI and blood of containing was declined, reach the object of blood pressure lowering, for hypertensive treatment, there is the advantage that curative effect is high, short treating period, instant effect, cost are low, have no side effect, economical and practical, each herbal medicine complements each other simultaneously, Synergistic, combined effect, in focus place, has splendid curative effect to hypertensive treatment.
Detailed description of the invention
Below in conjunction with specific embodiment, content of the present invention is described in further detail.
Embodiment 1
One treats hypertensive Chinese medicine composition, and it is made up of the crude drug of following weight: Semen Plantaginis 4g, Ramulus Uncariae Cum Uncis 10g, Semen Platycladi 5g, Herba Taxilli 5g, Rhizoma Acori Graminei 8g, Semen Cassiae 20g, Caulis Polygoni Multiflori 10g, Fructus Rubi 5g, Pheretima 10g, Fructus Schisandrae Chinensis 15g, Bulbus Lilii 15g, Radix Astragali 20g, Rhizoma Dioscoreae Septemlobae 12g, Cortex Cinnamomi 6g, Scorpio 10g, Radix Ophiopogonis 12g, Pollen Typhae 4g, Radix Asteris 3g, Rhizoma Curcumae 10g, Rhizoma Et Radix Notopterygii 20g, Caulis Spatholobi 15g, SHANZHIZI 10g, Bulbus Fritillariae Thunbergii 10g.
The preparation method of said medicine is as follows: take formula ratio material medicine according to quantity, adds 1000ml cold water soak wherein after 1 hour, first to burn to boiling slow fire boiling again 30 minutes with intense fire, filters to obtain a filtered juice; Continuing to add water 600ml decoction to seething with excitement latter 20 minutes in filtering residue, filtering to obtain secondary filtered juice; First and second filtered juice is merged centrifugalize or sedimentation filtration, then concentrated, dry, add after customary adjuvant makes granule sterilization and incapsulate, every heavy 0.5g.
Embodiment 2
One treats hypertensive Chinese medicine composition, and it is made up of the crude drug of following weight: Semen Plantaginis 6g, Ramulus Uncariae Cum Uncis 15g, Semen Platycladi 10g, Herba Taxilli 10g, Rhizoma Acori Graminei 14g, Semen Cassiae 25g, Caulis Polygoni Multiflori 15g, Fructus Rubi 10g, Pheretima 13g, Fructus Schisandrae Chinensis 20g, Bulbus Lilii 20g, Radix Astragali 25g, Rhizoma Dioscoreae Septemlobae 16g, Cortex Cinnamomi 10g, Scorpio 15g, Radix Ophiopogonis 14g, Pollen Typhae 8g, Radix Asteris 5g, Rhizoma Curcumae 15g, Rhizoma Et Radix Notopterygii 30g, Caulis Spatholobi 20g, SHANZHIZI 15g, Bulbus Fritillariae Thunbergii 15g.
The preparation method of said medicine is with embodiment 1.
Embodiment 3
One treats hypertensive Chinese medicine composition, and it is made up of the crude drug of following weight: Semen Plantaginis 8g, Ramulus Uncariae Cum Uncis 20g, Semen Platycladi 15g, Herba Taxilli 15g, Rhizoma Acori Graminei 16g, Semen Cassiae 30g, Caulis Polygoni Multiflori 20g, Fructus Rubi 15g, Pheretima 16g, Fructus Schisandrae Chinensis 25g, Bulbus Lilii 25g, Radix Astragali 30g, Rhizoma Dioscoreae Septemlobae 18g, Cortex Cinnamomi 12g, Scorpio 20g, Radix Ophiopogonis 16g, Pollen Typhae 10g, Radix Asteris 8g, Rhizoma Curcumae 20g, Rhizoma Et Radix Notopterygii 40g, Caulis Spatholobi 25g, SHANZHIZI 20g, Bulbus Fritillariae Thunbergii 20g.
The preparation method of said medicine is with embodiment 1.
Embodiment 4
One treats hypertensive Chinese medicine composition, and it is made up of the crude drug of following weight: Semen Plantaginis 5g, Ramulus Uncariae Cum Uncis 18g, Semen Platycladi 12g, Herba Taxilli 12g, Rhizoma Acori Graminei 10g, Semen Cassiae 28g, Caulis Polygoni Multiflori 14g, Fructus Rubi 12g, Pheretima 14g, Fructus Schisandrae Chinensis 18g, Bulbus Lilii 16g, Radix Astragali 26g, Rhizoma Dioscoreae Septemlobae 15g, Cortex Cinnamomi 10g, Scorpio 14g, Radix Ophiopogonis 15g, Pollen Typhae 9g, Radix Asteris 6g, Rhizoma Curcumae 12g, Rhizoma Et Radix Notopterygii 35g, Caulis Spatholobi 22g, SHANZHIZI 14g, Bulbus Fritillariae Thunbergii 18g.
The preparation method of said medicine is with embodiment 1.
Clinical practice example
1, clinical data
Hyperpietic 400 example selecting outpatient service to accept for medical treatment, wherein man 167 example, female 133 example, 55.6 years old mean age, is divided into 2 groups, i.e. treatment group and matched group at random.Two groups of cases through statistical analysis, have comparability in sex, age, the course of disease etc.
2, diagnostic criteria
Western medicine diagnose standard: systolic pressure >=140mmHg, diastolic pressure >=90mmHg, both have one to examine, and can make a definite diagnosis.Differential diagnosis in tcm standard cardinal symptom: dizzy, headache, cardiopalmus, tinnitus, insomnia, agitation, waist soreness etc.
3, Therapeutic Method
Treatment group takes medicine of the present invention, every day 3 times, one time 2, within 7 days, be a course for the treatment of, general 1 course for the treatment of can take effect, and 2-4 the course for the treatment of can cure.Matched group oral drugs 25mg metoprolol tartrate tablets, a 50mg, three times on the one.
4, curative effect determinate standard
Cure: clinical symptoms all disappears, and blood pressure is down to normally, and does not recur in 1 year.
Effective: clinical symptoms all disappears, after taking medicine, blood pressure declines to some extent but is not down to normal.
Invalid: clinical symptoms does not change, before and after treatment, blood pressure does not obviously change.
5, therapeutic outcome.
Through clinical treatment after 30 days, two groups of therapeutic outcome contrasts are as following table 1.
| Group | Case load | Cure n | Effective n | Invalid n | Total effective rate % |
| Treatment group | 200 | 165 | 33 | 2 | 99% |
| Matched group | 200 | 105 | 79 | 16 | 92% |
As can be seen from above therapeutic outcome data, treatment group has better therapeutic effect compared with matched group, and this illustrates that the hypertensive medicine for the treatment of of the present invention has curative effect more better than general Western medicine to hypertension, and suitable clinical expansion uses.
Model case
Example 1: Luo, man, 65 years old, suffers from hypertension more than 3 years, often has headache, dizziness, absent minded, cardiopalmus, the symptom such as uncomfortable in chest, weak.Be 179/98mmHg through measuring blood pressure, mainly take Western medicine relief of symptoms at ordinary times, but fail radical cure.After 1 course for the treatment of of rear use medicine of the present invention, blood pressure is reduced to 150/90mmHg, and rear continuation uses 2 courses for the treatment of of medicine of the present invention, and blood pressure is basically stable at 115/80mmHg, and clinical symptoms all disappears, and follows up a case by regular visits to 2 years for recurrence.
Example 2: Dong so-and-so, man, 72 years old, suffers from hypertension 16 years, often with the symptom such as dizzy, drowsiness, weak, spirit differs from, even there will be severe headache, vomiting, cardiopalmus, the symptom such as dizzy time serious.After taking 4 courses for the treatment of of medicine of the present invention, patients' blood is stabilized in 110-120/70-80mmHg, and clinical symptoms all disappears, and follows up a case by regular visits to and does not recur for 1 year.
Example 3: history, 56 years old, there is the clinical symptoms such as headache, dizzy, tinnitus, shortness of breath and palpitation, reaches 165/100mmHg, be diagnosed as hypertension through Measure blood pressure value in female before 3 years.After 3 courses for the treatment of of rear use Drug therapy of the present invention, clinical symptoms all disappears, and blood pressure is down to normal value, follows up a case by regular visits to and does not recur for 2 years half.
Example 4: Jiang, female, 45 years old, patient started to occur headache, dizzy, tinnitus, shortness of breath and palpitation, insomnia, numb limbs and tense tendons, hypomnesis before 2 years, the symptom such as feel run-down, also with feeling sick time serious, symptoms of emesis, Measure blood pressure is 155/95mmHg, is diagnosed as hypertension.After 2 courses for the treatment of of rear use medicine of the present invention, clinical symptoms all disappears, and blood pressure is normal, follows up a case by regular visits to and does not recur so far.
Claims (2)
1. the hypertensive Chinese medicine composition for the treatment of, it is characterized in that, it is made up of the crude drug of following weight portion: Semen Plantaginis 4-8 part, Ramulus Uncariae Cum Uncis 10-20 part, Semen Platycladi 5-15 part, Herba Taxilli 5-15 part, Rhizoma Acori Graminei 8-16 part, Semen Cassiae 20-30 part, Caulis Polygoni Multiflori 10-20 part, Fructus Rubi 5-15 part, Pheretima 10-16 part, Fructus Schisandrae Chinensis 15-25 part, Bulbus Lilii 15-25 part, Radix Astragali 20-30 part, Rhizoma Dioscoreae Septemlobae 12-18 part, Cortex Cinnamomi 6-12 part, Scorpio 10-20 part, Radix Ophiopogonis 12-16 part, Pollen Typhae 4-10 part, Radix Asteris 3-8 part, Rhizoma Curcumae 10-20 part, Rhizoma Et Radix Notopterygii 20-40 part, Caulis Spatholobi 15-25 part, SHANZHIZI 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part.
2. the hypertensive Chinese medicine composition for the treatment of according to claim 1, it is characterized in that, it is made up of the crude drug of following weight portion: Semen Plantaginis 6 parts, Ramulus Uncariae Cum Uncis 15 parts, Semen Platycladi 10 parts, Herba Taxilli 10 parts, Rhizoma Acori Graminei 14 parts, Semen Cassiae 25 parts, Caulis Polygoni Multiflori 15 parts, Fructus Rubi 10 parts, Pheretima 13 parts, Fructus Schisandrae Chinensis 20 parts, Bulbus Lilii 20 parts, the Radix Astragali 25 parts of, Rhizoma Dioscoreae Septemlobae 16 parts, Cortex Cinnamomi 10 parts, Scorpio 15 parts, Radix Ophiopogonis 14 parts, Pollen Typhae 8 parts, Radix Asteris 5 parts, Rhizoma Curcumae 15 parts, Rhizoma Et Radix Notopterygii 30 parts, Caulis Spatholobi 20 parts, SHANZHIZI 15 parts, Bulbus Fritillariae Thunbergii 15 parts.
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