CN104667007A

CN104667007A - Traditional Chinese medicine composition for treating qi and yin deficiency diabetes and preparation method of traditional Chinese medicine composition

Info

Publication number: CN104667007A
Application number: CN201510110999.XA
Authority: CN
Inventors: 陈彬
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-03-15
Filing date: 2015-03-15
Publication date: 2015-06-03

Abstract

The invention discloses traditional Chinese medicine composition for treating qi and yin deficiency diabetes and a preparation method of the traditional Chinese medicine composition. The is characterized by being prepared from the following medicinal materials in parts by weight: 10-25 parts of crystobalite, 15-30 parts of aralia elata, 10-25 parts of asfragalus monadelphus bnnge, 30-45 parts of club bottle gourd fruit, 3-13 parts of stevia rebaudiana, 6-15 parts of radix liriopes, 5-20 parts of cocoon chrysalis, 7-20 parts of radix seu spiranthis lanceae, meadow grass, 5-20 parts of astragalus tibetanus benth ex bunge, 7-20 parts of root of intermediate peashrub, 5-20 parts of glycine max, 30-45 parts of lance asiabell root, 7-20 parts of disporopsis longifolia and 3-12 parts of liquorice. The traditional Chinese medicine composition is used for treating the qi and yin deficiency diabetes and has the advantages of high efficiency, reliable curative effect and no recurrence after curing.

Description

A kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus and preparation method thereof.

Background technology

The metabolic disease of diabetes to be one group with hyperglycemia be feature.Its occurrence cause mainly contain following some: 1., eating and drinking without temperance.Surfeit delicious food, pure wine savoury, impairing the spleen and stomach, dysfunction of the spleen in transportation, leads to interior-heat, and rapid digestion of food consumption essence, sends out as quenching one's thirst.2., feelings will is uncomfortable.Overaction of the five emotions, strongly fragrant and fire-transformation, disappear bright body fluid, and initiation is quenched one's thirst.3., work and rest mistake degree.The people that the ferritic deficiency of YIN, the five internal organs are weak, work and rest mistake degree, chamber is forfeited one's integrity, bringing about the spread of body fluid's loss, and kidney yin is impaired, and kidney loses astringency inducing, precise and tiny bet, therefore disappears under being.Its clinical manifestation is asymptomatic in early days, develops into the symptom phase, can occur polydipsia, polyphagia, polyuria, tired, the syndrome such as to become thin clinically, time serious, ketoacidosis occur.Diabetes are not fearful, and fearful is diabetic complication, so treatment diabetes are imperative.At present, the treatment of diabetes mainly contains western medicine, treatment by Chinese herbs, insulinize.The treatment of long-term hypoglycemic medicine can produce burden to liver kidney and other organs, and therapeutic effect worse and worse.Although insulinize effectively can control blood glucose, along with the development of the state of an illness, consumption can get more and more, and is difficult to the complication stopping diabetes.The traditional Chinese medical science effectively can be treated and be improved diabetes clinical symptoms, corrects lipid metabolic disorder in time, helps the discharge of abnormal sugar, protein, lipid metabolism product, effectively can prevent and treat complication.The different times of the femur head necrosis that the traditional Chinese medical science causes according to different reason and progression of disease, carries out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, is divided into by primary disease: deficiency of YIN dryness-heat type, type of deficiency of both QI and YIN, deficiency of both YIN and YANG type, blood stasis accompanied symptoms type, negative and positive type wild.At present, the Chinese medicine for the treatment of diabetes has multiple, but the Chinese medicine being directed to treatment Qi and Yin deficiency diabetes mellitus is actually rare, but also there is the defects such as cure rate is low.

Summary of the invention

For solving above-mentioned existing shortcoming, main purpose of the present invention is Chinese medicine composition of the treatment Qi and Yin deficiency diabetes mellitus providing a kind of practicality and preparation method thereof, by selecting suitable medical material and proportioning thereof, reach the object of safe and effective healing Qi and Yin deficiency diabetes mellitus.

For reaching above-described object, one of the present invention is treated Qi and Yin deficiency diabetes mellitus and preparation method thereof and is taked following technical scheme:

Treat a Chinese medicine composition for Qi and Yin deficiency diabetes mellitus, it is characterized in that, be made up of the medical material of following weight proportion:

Quartz Album 10-25 part, thorn fossilia dentis mastodi 15-30 part, Radix Astragali 10-25 part, Pericarpium Lagenariae hispidae 30-45 part, Folium Stevlae Rebaudianae 3-13 part, Radix Liriopes 6-15 part, Antheraea pernyi Geurin Meneville 5-20 part, Radix seu Herba Spiranthis Lanceae 7-20 part, English grass 5-20 part, hide continuous stilbene 5-20 part, Radix Caraganae intermediae 7-20 Fen, Semen sojae atricolor 5-20 part, Radix Codonopsis Lanceolatae 30-45 part, Rhizoma Tupistrae Chinensis 7-20 part of coming into leaves, Radix Glycyrrhizae 3-12 part.

The present invention is a kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus preferably, it is characterized in that, is made up of the medical material of following weight proportion:

Quartz Album 15-20 part, thorn fossilia dentis mastodi 20-25 part, Radix Astragali 15-20 part, Pericarpium Lagenariae hispidae 35-40 part, Folium Stevlae Rebaudianae 6-10 part, Radix Liriopes 9-12 part, Antheraea pernyi Geurin Meneville 10-15 part, Radix seu Herba Spiranthis Lanceae 12-15 part, English grass 10-15 part, hide continuous stilbene 10-15 part, Radix Caraganae intermediae 12-15 Fen, Semen sojae atricolor 10-15 part, Radix Codonopsis Lanceolatae 35-40 part, Rhizoma Tupistrae Chinensis 12-15 part of coming into leaves, Radix Glycyrrhizae 6-9 part.

A kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus of the best of the present invention, is characterized in that, be made up of the medical material of following weight proportion:

Quartz Album 17 parts, thorn fossilia dentis mastodi 22 parts, Radix Astragali 17 parts, Pericarpium Lagenariae hispidae 37 parts, Folium Stevlae Rebaudianae 8 parts, Radix Liriopes 10 parts, Antheraea pernyi Geurin Meneville 13 parts, Radix seu Herba Spiranthis Lanceae 14 parts, English grass 12 parts, hide continuous stilbene 12 parts, Radix Caraganae intermediae 14 Fen, Semen sojae atricolor 13 parts, Radix Codonopsis Lanceolatae 37 parts, the Rhizoma Tupistrae Chinensis 14 parts that comes into leaves, 8 parts, Radix Glycyrrhizae.

A kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus of the present invention, is characterized in that, adopts following method to prepare:

A: take the Quartz Album of weight proportion, thorn fossilia dentis mastodi, Radix Astragali, Pericarpium Lagenariae hispidae, Folium Stevlae Rebaudianae, Radix Liriopes, Antheraea pernyi Geurin Meneville, Radix seu Herba Spiranthis Lanceae, English grass, Tibetan continuous stilbene, Radix Caraganae intermediae, Semen sojae atricolor, Radix Codonopsis Lanceolatae, come into leaves Rhizoma Tupistrae Chinensis and Radix Glycyrrhizae for subsequent use;

B: above-mentioned ten gomi herbs are poured in vessel, whole grinding becomes end, then uses " whole part " method to extract and makes instant Chinese medicine granule;

C: carry out subpackage according to every pouch 5 grams, airtight, preserve in shady and cool, dry place.

Source and the function of medical material involved in formula cure mainly as follows:

Quartz Album [source] medical material Ji Yuan: be the Ore of oxide-based mineral quartz.[nature and flavor] are sweet; Pungent; Temperature; Nontoxic [return through] lung; Kidney; Heart channel [function cures mainly] warming the lung kidney; Tranquilizing mind; Diuresis.Main lung cold cough with asthma; Sexual impotence; Quench one's thirst; Irritability; Palpitate with fear forgetful; Dysuria; Jaundice; Stony edema; Anemofrigid-damp arthralgia.

Thorn fossilia dentis mastodi [source] medical material Ji Yuan: be root bark and the bark of the eastern Cortex araliae chinensis of Araliaceae the Liao Dynasty.[nature and flavor] acrid in the mouth; Micro-hardship; Sweet; Property flat [function cures mainly] vital energy benefiting and the kidney invigorating; Expelling wind and removing dampness; Promoting blood circulation and stopping pain.The main deficiency of vital energy is weak; Impotence due to deficiency of the kidney; Gastric abscess; Quench one's thirst; Insomnia and dreamful sleep; Rheumatoid bone bi-syndrome; Weakness of the waist and knees; Traumatic injury; Fracture; Expand; Edema; Proctoptosis; Scabies.

Radix Astragali [source] pulse family Radix Astragali, is used as medicine with root.[nature and flavor] are sweet, temperature.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.

Pericarpium Lagenariae hispidae [source] medical material Ji Yuan: be the fruit of cucurbitaceous plant Pericarpium Lagenariae hispidae.[nature and flavor] sweet in the mouth; Property flat [function cures mainly] diuretic; Heat clearing away; Quench the thirst; Relieving restlessness.Main edema abdominal distention, dysphoria with smothery sensation is thirsty; Sore.

Folium Stevlae Rebaudianae [source] medical material Ji Yuan: be the leaf of feverfew Folium Stevlae Rebaudianae.[nature and flavor] sweet in the mouth; Property flat [function cures mainly] promoting the production of body fluid to quench thirst; Blood pressure lowering.Master quenches one's thirst; Hypertension.

Radix Liriopes [source] this product is the dried root of liliaceous plant Hubei Radix Ophiopogonis or liriope muscari Baily.Early summer is excavated, and cleans, is repeatedly exposed to the sun, banks up, near dry, and removing fibrous root, dry.[nature and flavor] sweet, micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, cough due to consumptive disease, Tianjin wound is thirsty, vexed insomnia, dryness of the intestine constipation.

Antheraea pernyi Geurin Meneville [source] medical material Ji Yuan: be the pupa of giant silkworm section animal Antherea pernyi Guerin-Meneville.[nature and flavor] are sweet; Light; Cool [return through] stomach; Lung; Liver; Kidney channel [function cures mainly] promoting the production of body fluid to quench thirst; Relieving convulsion.Main frequent micturition of quenching one's thirst; Epilepsy clonus.

Radix seu Herba Spiranthis Lanceae [source] medical material Ji Yuan: be root and the herb of orchid Radix seu Herba Spiranthis Lanceae.[nature and flavor] are sweet; Bitter; Flat [return through] heart; Lung meridian [function cures mainly] supplementing QI and nourishing YIN; Heat-clearing and toxic substances removing.Main weak after being ill; Yin asthenia generating intrinsic heat; Cough is spitted blood; Dizzy; Lumbago is aching and limp; Diabetes; Seminal emission; Stranguria with turbid discharge leukorrhagia; Laryngopharynx swelling and pain; Venom; Burn and scald; Skin infection carbuncle.

English grass [source] medical material Ji Yuan: be the rhizome of grass English grass.[function cures mainly] blood sugar lowering.Main diabetes.

Hide continuous stilbene [source] pulse family and hide continuous stilbene, be used as medicine with root.[nature and flavor] are sweet, warm.[function cures mainly] strong QI invigorating, evacuation of pus granulation promoting, diuresis hidroschesis.Control valetudinarianism, chronic nephritis edema, dyspepsia, anemia, spontaneous perspiration, night sweat, diabetes, carbuncle furuncle, dysentery, menoxenia, leukorrhagia.

Radix Caraganae intermediae [source] medical material Ji Yuan: be the root of leguminous plant Caragana intermedia.[nature and flavor] are micro-pungent; Temperature [the return through] heart; Liver Channel [function cures mainly] supplementing QI and nourishing YIN.Main dizziness, cardiopalmus, shortness of breath and fatigue, hypertension.

[source] Dou Ke Semen sojae atricolor, is used as medicine with seed Semen sojae atricolor.[function cures mainly] tonifying speen and tonifying kidney, yin nourishing relieving restlessness.Cure mainly deficiency of YIN dysphoria with smothery sensation, spontaneous sweating, rheumatic Bi syndrome.

The root that Radix Codonopsis Lanceolatae [source] is Campanulaceae Lac caprae seu ovis.Spring, autumn dig, removing fibrous root, and rip cutting is dried; Or section is dried after steaming.[nature and flavor] are warm in nature, sweet in the mouth.Effect of [function cures mainly] QI invigorating, yin nourishing, detumescence, removing toxic substances.For physical weakness, myasthenia of limbs, dizziness headache, cough due to yin deficiency, hypogalactia, lung abscess, mastitis, treatment skin ulcer, insect bite etc.

Come into leaves Rhizoma Tupistrae Chinensis [source] medical material Ji Yuan: for liliaceous plant comes into leaves the rhizome of Rhizoma Tupistrae Chinensis.[nature and flavor] sweet in the mouth; Micro-pungent; Property flat [function cures mainly] supplementing QI and nourishing YIN lung moistening; Invigorate blood circulation.Main body is after being ill empty; Lung-dryness syndrome due to deficiency of YIN; Cough with ropy sputum; Dry throat and mouth; Traumatic injury.

Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Qi and Yin deficiency diabetes mellitus clinical manifestation is weak, breathes hard, spontaneous perspiration, dynamic then increase the weight of, dry mouth and tougue, polydipsia polyuria, dysphoria with feverish sensation in the chest palms and soles, constipation, soreness of the waist and knees, light red tongue or red tongue dark, indentations at the margin of the tongue, the few Tianjin of white and thin fur, or few tongue, thready and weak pulse.Above various raw material is organically combined by the present invention, mutually coordinates between each composition, interacts, can treating both the principal and secondary aspects of a disease to Qi and Yin deficiency diabetes mellitus, respond well, fundamentally treats this disease.For many years, by the follow-up investigation statistics to 100 these type of patients of example, show that this prescription effective percentage reaches 94%.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, sampling approach

Be diagnosed as the patient of Qi and Yin deficiency diabetes mellitus from my unit over nearly 5 years, the routine patient of random selecting 110, in age 15-60 year, be divided into matched group and treatment group at random, often organize each 55 people.The data there was no significant differences such as two groups of ages, have comparability.

2, test method

2.1 matched group patients use glimepiride, and by specification is taken, 6 weeks courses for the treatment of.

The oral the present invention of 2.2 treatment group according to the obtained capsule of specific embodiment 1, early, middle and late each once.6 weeks courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterions of therapeutical effect:

Clinical recovery: clinical symptoms, the sign of Qi and Yin deficiency diabetes mellitus disappear or substantially disappear; Effective: clinical symptoms, the sign of Qi and Yin deficiency diabetes mellitus are obviously improved; Effective: clinical symptoms, the sign of Qi and Yin deficiency diabetes mellitus all take a favorable turn; Invalid: clinical symptoms, the sign of Qi and Yin deficiency diabetes mellitus are all not improved or increase the weight of.

3.2 treatment statistical results are in table 1.

Table 1 liang group comparitive study

Enumerate three model cases below and further illustrate effect of the present invention:

1, in certain, man, nineteen sixty be born, 50 years old, diabetes medical history 5 years, fasting glucose 11.2mmol/L, with weak, breathe hard, constipation, took metformin, gliclazide once, glycemic control is not obvious, is diagnosed as Qi and Yin deficiency diabetes mellitus in here.After taking 1 course for the treatment of of this prescription, symptom is alleviated to some extent, and after 2 courses for the treatment of, symptom obviously alleviates, and after 3 courses for the treatment of, symptom disappears entirely, and blood sugar recovery is normal, and it is steady so far to follow up a case by regular visits to 1 year state of an illness.

2, Wang, female, birth in 1980,30 years old, xerostomia, polydipsia, January of becoming thin accompanied weak, and fasting glucose 13.9 mmol/L, routine urianlysis ketoboidies (++), with soreness of the waist and knees, dysphoria with feverish sensation in the chest palms and soles, is diagnosed as Qi and Yin deficiency diabetes mellitus in here.After taking 1 course for the treatment of of this prescription, its remission, after 2 courses for the treatment of, symptom is obviously alleviated, after take again 2 courses for the treatment of continuously, symptom disappears entirely, and blood sugar recovery is normal, and it is steady so far to follow up a case by regular visits to 1 year state of an illness.

3, thank certain, man, 1948 birth, 62 years old, cadre, diabetes medical history 8 years, with malaise, breathe hard, spontaneous perspiration, dry mouth and tougue, constipation, is diagnosed as Qi and Yin deficiency diabetes mellitus in here.After taking 1 course for the treatment of of this prescription, symptom is namely basic to disappear, after take again 1 course for the treatment of and carried out after treatment, symptom disappears entirely, and blood sugar recovery is normal, and it is steady so far to follow up a case by regular visits to 1 year state of an illness.

Detailed description of the invention

In order to Comprehension and Implementation the present invention better, below in conjunction with the concrete example implemented, further detailed description is done to the present invention.

Embodiment 1

Take Quartz Album 15 grams, thorn fossilia dentis mastodi 20 grams, Radix Astragali 15 grams, Pericarpium Lagenariae hispidae 35 grams, Folium Stevlae Rebaudianae 6 grams, Radix Liriopes 9 grams, Antheraea pernyi Geurin Meneville 10 grams, Radix seu Herba Spiranthis Lanceae 12 grams, English grass 10 grams, hide continuous stilbene 10 grams, Radix Caraganae intermediae 12 Ke, Semen sojae atricolor 10 grams, Radix Codonopsis Lanceolatae 35 grams, the Rhizoma Tupistrae Chinensis 12 grams that comes into leaves, 6 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 5 grams, airtight, preserve in shady and cool, dry place.

Be used for the treatment of Qi and Yin deficiency diabetes mellitus.Oral, early, middle and late three one after each meals of every bu.

Embodiment 2

Take Quartz Album 17 grams, thorn fossilia dentis mastodi 22 grams, Radix Astragali 17 grams, Pericarpium Lagenariae hispidae 37 grams, Folium Stevlae Rebaudianae 8 grams, Radix Liriopes 10 grams, Antheraea pernyi Geurin Meneville 13 grams, Radix seu Herba Spiranthis Lanceae 14 grams, English grass 12 grams, hide continuous stilbene 12 grams, Radix Caraganae intermediae 14 Ke, Semen sojae atricolor 13 grams, Radix Codonopsis Lanceolatae 37 grams, the Rhizoma Tupistrae Chinensis 14 grams that comes into leaves, 8 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 5 grams, airtight, preserve in shady and cool, dry place.

Embodiment 3

Take Quartz Album 20 grams, thorn fossilia dentis mastodi 25 grams, Radix Astragali 20 grams, Pericarpium Lagenariae hispidae 40 grams, Folium Stevlae Rebaudianae 10 grams, Radix Liriopes 12 grams, Antheraea pernyi Geurin Meneville 15 grams, Radix seu Herba Spiranthis Lanceae 15 grams, English grass 15 grams, hide continuous stilbene 15 grams, Radix Caraganae intermediae 15 Ke, Semen sojae atricolor 15 grams, Radix Codonopsis Lanceolatae 40 grams, the Rhizoma Tupistrae Chinensis 15 grams that comes into leaves, 9 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 5 grams, airtight, preserve in shady and cool, dry place.

Embodiment 4

Take Quartz Album 10 grams, thorn fossilia dentis mastodi 15 grams, Radix Astragali 10 grams, Pericarpium Lagenariae hispidae 30 grams, Folium Stevlae Rebaudianae 3 grams, Radix Liriopes 6 grams, Antheraea pernyi Geurin Meneville 5 grams, Radix seu Herba Spiranthis Lanceae 7 grams, English grass 5 grams, hide continuous stilbene 5 grams, Radix Caraganae intermediae 7 Ke, Semen sojae atricolor 5 grams, Radix Codonopsis Lanceolatae 30 grams, the Rhizoma Tupistrae Chinensis 7 grams that comes into leaves, 3 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 5 grams, airtight, preserve in shady and cool, dry place.

Embodiment 5

Take Quartz Album 25 grams, thorn fossilia dentis mastodi 30 grams, Radix Astragali 25 grams, Pericarpium Lagenariae hispidae 45 grams, Folium Stevlae Rebaudianae 13 grams, Radix Liriopes 15 grams, Antheraea pernyi Geurin Meneville 20 grams, Radix seu Herba Spiranthis Lanceae 20 grams, English grass 20 grams, hide continuous stilbene 20 grams, Radix Caraganae intermediae 20 Ke, Semen sojae atricolor 20 grams, Radix Codonopsis Lanceolatae 45 grams, the Rhizoma Tupistrae Chinensis 20 grams that comes into leaves, 12 grams, Radix Glycyrrhizae.Above various medical material grinding is become end, then uses " whole part " method to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 5 grams, airtight, preserve in shady and cool, dry place.

More than by description of listed embodiment, the basic ideas and basic principles of the present invention are set forth.But the present invention is never limited to above-mentioned listed embodiment, every equivalent variations, the improvement done based on technical scheme of the present invention and deliberately become of inferior quality behavior, all should belong to protection scope of the present invention.

Claims

1. treat a Chinese medicine composition for Qi and Yin deficiency diabetes mellitus, it is characterized in that, be made up of the medical material of following weight proportion:

2. a kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus according to claim 1, is characterized in that, be made up of the medical material of following weight proportion:

3. a kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus according to claim 1, is characterized in that, be made up of the medical material of following weight proportion:

4., according to the arbitrary described a kind of Chinese medicine composition for the treatment of Qi and Yin deficiency diabetes mellitus of claims 1 to 3, it is characterized in that, adopt following method to prepare: