CN104666875A

CN104666875A - Oral care solution and preparation method thereof

Info

Publication number: CN104666875A
Application number: CN201510092413.1A
Authority: CN
Inventors: 杨朝霞; 党和勤; 曾伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-03-02
Filing date: 2015-03-02
Publication date: 2015-06-03

Abstract

The invention discloses an oral care solution which comprises honeysuckle flowers, dandelions, Philippine violet herbs, amur corktree bark, dried rehmannia roots, figwort roots, dwarf lilyturf tubers, common anemarrhena rhizomes, wrinkled gianthyssop herbs, aloe, cloves, common andrographis herbs, heartleaf houttuynia herbs and indigowoad roots. The prepared oral care solution is simple in method, low in cost, free of any additive, safe, reliable and good in taste, has the effect of significantly killing bacteria in the oral cavity and can decrease internal fire, diminish inflammations and accelerate healing of oral ulcers.

Description

A kind of oral nursing liquid and preparation method thereof

Technical field

The invention belongs to field of medicaments, be specifically related to a kind of oral nursing liquid and preparation method thereof.

Background technology

Some people in the test period, or is being busy with one's work, and has a rest bad, or has dyspepsia, or women is premenstrual in the moon, inside lip, at the bottom of mouth, often there are single or two or three circular or ovate aphthas in soft palate or tongue, and feel burning pain, this disease, oral ulcer, is commonly called as aphtha.

Oral ulcer Early manifestation is small red dot, expands gradually, the mucosa superficial ulcer of 2 ~ 3 millimeters or larger, and its ulcer surface is as vegetable dish shape, and rounded or oval, ulcer surface nick as at the bottom of vegetable dish, and has the faint yellow plastic film covering of one deck, is called pseudomembrane.Its surrounding can see a congested band, in blush shape, can have spontaneous pain or because producing pain after food stimulus, as heat, and acid, peppery, firmly, friedly wait food stimulus.

Oral ulcer is usually periodical attack, and recurrence time length and oral ulcer medical history length have substantial connection, medical history in short-term, can some months or 1 year morbidity once; When medical history is long, can fall ill once for one month, or the new and old pathological changes of oral ulcer alternately occurs.The definite cause of disease of this disease it be unclear that, but clinical observation is relevant with following factor to recurrence.(1) inherited genetic factors: can question closely its father and mother from the family history of recurrent aphtha patient has aphtha medical history.(2) role of autoimmune factors: many research datas prove, in the serum of recurrent aphthous ulcer patient, can find that immunoglobulin A and immunoglobulin G increase.(3) other diseases: clinical data shows, has during following disease and stomatocace can be caused to recur.As gastric ulcer, duodenal ulcer, chronic or chronic persistent hepatitis, colitis, anemia, monophagia, dyspepsia, diarrhoea, constipation, does not have enough sleep, tired, menstrual phase etc.

The sickness rate of oral ulcer in crowd can reach more than 30%.Some people often understands dry mouth and tougue, even bitterly all can have any problem to east two of drinking water, eat because of " mouth breaks ".Common people think.Oral ulcer can be fully recovered voluntarily in 7 ~ 10 days, and problem is that the state of an illness of many patients often seems again and again, bad during fashion, affects diet and daily life, made us puzzlement.

Traditional oral nursing liquid dissolves by ethanol, water, wetting agent, spice, solubilizing agent and the additive that comprises various antipathogenic composition the liquid formed.The obtained oral nursing liquid of general Chinese herbal medicine extract inevitably exists that active matter content is low, content is difficult to determine, solvent composition is difficult to problems such as removing, gained composition is too complicated, is very easy to the use mouthfeel affecting collutory.And add the adjuvants such as a large amount of spice, solubilizing agent, affect the healthy of people.

Summary of the invention

An object of the present invention is low for solving Chinese herbal medicine oral nursing liquid active matter content, and the problem of mouthfeel discomfort, provides a kind of new oral nursing liquid and preparation method thereof.

A kind of oral nursing liquid provided by the invention, comprising: Flos Lonicerae, Herba Taraxaci, Herba Violae, Cortex Phellodendri, the Radix Rehmanniae, Radix Scrophulariae, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Herba Pogostemonis, Aloe, Flos Caryophylli, Herba Andrographis, Herba Houttuyniae and Radix Isatidis.

Further, described oral nursing liquid, in mass fraction, comprising: Flos Lonicerae 15-30 part, Herba Taraxaci 15-20 part, Herba Violae 10-15 part, Cortex Phellodendri 5-10 part, Radix Rehmanniae 5-10 part, Radix Scrophulariae 5-10 part, Radix Ophiopogonis 10-15 part, Rhizoma Anemarrhenae 10-15 part, Herba Pogostemonis 5-10 part, Aloe 5-10 part, Flos Caryophylli 5-10 part, Herba Andrographis 5-10 part, Herba Houttuyniae 5-10 part and Radix Isatidis 10-15 part.

Further, described oral nursing liquid, in mass fraction, comprising: Flos Lonicerae 20 parts, Herba Taraxaci 15 parts, Herba Violae 10 parts, Cortex Phellodendri 8 parts, 8 parts, the Radix Rehmanniae, Radix Scrophulariae 5 parts, Radix Ophiopogonis 12 parts, the Rhizoma Anemarrhenae 15 parts, Herba Pogostemonis 5 parts, Aloe 5 parts, Flos Caryophylli 5 parts, Herba Andrographis 10 parts, Herba Houttuyniae 5 parts and Radix Isatidis 10 parts.

Further, described oral nursing liquid also comprises excipient.

Further, described excipient comprises water.

Present invention also offers a kind of preparation method of above-mentioned oral nursing liquid, comprise the following steps:

(1) extracting honeysuckle, Herba Taraxaci, Herba Violae, Cortex Phellodendri, the Radix Rehmanniae, Radix Scrophulariae, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Herba Pogostemonis, Aloe, Flos Caryophylli, Herba Andrographis, Herba Houttuyniae and Radix Isatidis, add 1000ml water boiling decoction 2 times, each 2 hours, filter, merge twice filtrate;

(2) described filtrate centrifuge, gets supernatant, adds active carbon and stirs and be filtered to after 15min clear and bright, then add ultrafiltration after water for injection, obtain ultrafiltrate;

(3) described ultrafiltrate fill sealing by fusing under dust-free sterile condition, 100 DEG C of flowing steam sterilizations 30 minutes, obtain described oral nursing liquid.

Further, described active carbon addition is 1% of supernatant weight.

Beneficial effect of the present invention is: oral nursing liquid method prepared by the present invention is simple, with low cost, without any additive, safe and reliable, good mouthfeel, and has the effect killing oral cavity bacterium significantly, pathogenic fire reducing antiinflammatory, accelerates the healing of oral ulcer.

Detailed description of the invention

Hereafter will describe the present invention in detail in conjunction with specific embodiments.It should be noted that the combination of technical characteristic or the technical characteristic described in following embodiment should not be considered to isolated, they can mutually be combined thus be reached better technique effect.

Embodiment one, extracting honeysuckle 60 parts, Herba Taraxaci 60 parts, Herba Violae 40 parts, Cortex Phellodendri 20 parts, 20 parts, the Radix Rehmanniae, Radix Scrophulariae 20 parts, Radix Ophiopogonis 40 parts, the Rhizoma Anemarrhenae 40 parts, Herba Pogostemonis 20 parts, Aloe 20 parts, Flos Caryophylli 20 parts, Herba Andrographis 20 parts, Herba Houttuyniae 20 parts and Radix Isatidis 40 parts, add 1000ml water boiling decoction 2 times, each 2 hours, filter, merge twice filtrate; Filtrate centrifuge, gets supernatant, adds active carbon and stirs and be filtered to after 15min clear and bright, then add ultrafiltration after water for injection, obtain ultrafiltrate; Ultrafiltrate is fill sealing by fusing under dust-free sterile condition, and 100 DEG C of flowing steam sterilizations 30 minutes, obtain described oral nursing liquid.

Embodiment two, extracting honeysuckle 90 parts, Herba Taraxaci 60 parts, Herba Violae 45 parts, Cortex Phellodendri 30 parts, 30 parts, the Radix Rehmanniae, Radix Scrophulariae 30 parts, Radix Ophiopogonis 45 parts, the Rhizoma Anemarrhenae 45 parts, Herba Pogostemonis 30 parts, Aloe 30 parts, Flos Caryophylli 30 parts, Herba Andrographis 30 parts, Herba Houttuyniae 30 parts and Radix Isatidis 45 parts, add 1000ml water boiling decoction 2 times, each 2 hours, filter, merge twice filtrate; Filtrate centrifuge, gets supernatant, adds active carbon and stirs and be filtered to after 15min clear and bright, then add ultrafiltration after water for injection, obtain ultrafiltrate; Ultrafiltrate is fill sealing by fusing under dust-free sterile condition, and 100 DEG C of flowing steam sterilizations 30 minutes, obtain described oral nursing liquid.

Embodiment three, extracting honeysuckle 20 parts, Herba Taraxaci 15 parts, Herba Violae 10 parts, Cortex Phellodendri 8 parts, 8 parts, the Radix Rehmanniae, Radix Scrophulariae 5 parts, Radix Ophiopogonis 12 parts, the Rhizoma Anemarrhenae 15 parts, Herba Pogostemonis 5 parts, Aloe 5 parts, Flos Caryophylli 5 parts, Herba Andrographis 10 parts, Herba Houttuyniae 5 parts and Radix Isatidis 10 parts, add 1000ml water boiling decoction 2 times, each 2 hours, filter, merge twice filtrate; Filtrate centrifuge, gets supernatant, adds active carbon and stirs and be filtered to after 15min clear and bright, then add ultrafiltration after water for injection, obtain ultrafiltrate; Ultrafiltrate is fill sealing by fusing under dust-free sterile condition, and 100 DEG C of flowing steam sterilizations 30 minutes, obtain described oral nursing liquid.

Oral nursing liquid method prepared by the present invention is simple, with low cost, without any additive, safe and reliable, good mouthfeel, and has the effect killing oral cavity bacterium significantly, pathogenic fire reducing antiinflammatory, accelerates the healing of oral ulcer.

Although give some embodiments of the present invention, it will be understood by those of skill in the art that without departing from the spirit of the invention herein, can change embodiment herein.Above-described embodiment is exemplary, should using embodiment herein as the restriction of interest field of the present invention.

Claims

1. an oral nursing liquid, is characterized in that, comprising: Flos Lonicerae, Herba Taraxaci, Herba Violae, Cortex Phellodendri, the Radix Rehmanniae, Radix Scrophulariae, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Herba Pogostemonis, Aloe, Flos Caryophylli, Herba Andrographis, Herba Houttuyniae and Radix Isatidis.

2. oral nursing liquid as claimed in claim 1, it is characterized in that, described oral nursing liquid, in mass fraction, comprising: Flos Lonicerae 15-30 part, Herba Taraxaci 15-20 part, Herba Violae 10-15 part, Cortex Phellodendri 5-10 part, Radix Rehmanniae 5-10 part, Radix Scrophulariae 5-10 part, Radix Ophiopogonis 10-15 part, Rhizoma Anemarrhenae 10-15 part, Herba Pogostemonis 5-10 part, Aloe 5-10 part, Flos Caryophylli 5-10 part, Herba Andrographis 5-10 part, Herba Houttuyniae 5-10 part and Radix Isatidis 10-15 part.

3. oral nursing liquid as claimed in claim 2, it is characterized in that, described oral nursing liquid, in mass fraction, comprising: Flos Lonicerae 20 parts, Herba Taraxaci 15 parts, Herba Violae 10 parts, Cortex Phellodendri 8 parts, 8 parts, the Radix Rehmanniae, Radix Scrophulariae 5 parts, Radix Ophiopogonis 12 parts, the Rhizoma Anemarrhenae 15 parts, Herba Pogostemonis 5 parts, Aloe 5 parts, Flos Caryophylli 5 parts, Herba Andrographis 10 parts, Herba Houttuyniae 5 parts and Radix Isatidis 10 parts.

4. the oral nursing liquid as described in any one of claim 1-3, is characterized in that, described oral nursing liquid also comprises excipient.

5. oral nursing liquid as claimed in claim 4, it is characterized in that, described excipient comprises water.

6. a preparation method for oral nursing liquid, is characterized in that, described oral nursing liquid as claimed in claim 1.

7. the preparation method of oral nursing liquid as claimed in claim 6, it is characterized in that, described preparation method comprises the following steps:

(1) extracting honeysuckle, Herba Taraxaci, Herba Violae, Cortex Phellodendri, the Radix Rehmanniae, Radix Scrophulariae, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Herba Pogostemonis, Aloe, Flos Caryophylli, Herba Andrographis, Herba Houttuyniae and Radix Isatidis, add 1000 parts of water boiling decoctions 2 times, each 2 hours, filter, merge twice filtrate;

8. the preparation method of oral nursing liquid according to claim 7, is characterized in that: described in step (2), active carbon addition is 1% of described supernatant weight.