CN102133366A - Traditional Chinese medicine composition for treating infant acute bacillary dysentery - Google Patents

Abstract

The invention discloses a traditional Chinese medicine enema for treating infant acute bacillary dysentery, which is prepared from the following raw medicines in parts by weight: 6 parts of licorice, 15 parts of Chinese pulsatilla, 16 parts of dangshen, 12 parts of bighead atractylodes rhizome, 18 parts of tuckahoe, 5 parts of hawthorn, 9 parts of cortex fraxini, 4 parts of phellodendron bark, 1 part of coptis, 6 parts of sophora flower, 1 part of amomun fruit, 12 parts of angelica, 15 parts of purslane, 4 parts of costus root, 10 parts of charred betel nut, 2 parts of sanguisorba, 2 parts of costus root, 5 parts of dried orange peel, 2 parts of gizzard pepsin, 8 parts of stellaria root and 5 parts of kudzu root. The traditional Chinese medicine enema disclosed by the invention is a pure traditional Chinese medicine component, has the characteristics of reasonable prescription, obvious treatment effect and the like, and is simple and convenient to take. Among 60 clinical application cases, the total effective rate reaches 100%.

Description

A kind of Chinese medicine composition for the treatment of acute bacterial dysentery in children

Technical field

The present invention relates to a kind of Chinese medicine for the treatment of dysentery, particularly a kind of Chinese medicine composition for the treatment of acute bacterial dysentery in children.

Background technology

Acute bacillary dysentery is mainly in summer and autumn, is with stomachache, diarrhoea, tenesmus and mucus bloody purulent stool, can be the acute infectious intestinal disease of feature with heating and whole body toxemia synptom.

Acute bacillary dysentery (acute bacillary dysentery) has another name called acute shigellosis, is by the bacterial acute infectious disease of the digestive tract of Shigella.In China, acute bacillary dysentery is still a kind of of commonly encountered diseases, frequently-occurring disease, and people's health in serious harm.The cardinal symptom of typical case's acute bacillary dysentery is that onset is anxious, heating, headache, stomachache, diarrhoea, bowel sound hyperaction, the left lower quadrant tenderness, tenesmus, mucus bloody purulent stool, and moderate whole body poisoning symptom arranged, diarrhoea reaches 10 times/d or more, but each stool amount is few, because of the number of times of suffering from diarrhoea every day too many, lax, the proctoptosis of anal sphincter can appear in the patient, and dehydration, metabolic acidosis are arranged.

The herbal retention enema genealogy of law pours into the Chinese medicine medicine juice from anus, remain in rectum or colonic, absorbs by intestinal mucosa, reaches a kind of therapy of treatment disease.Han dynasty well-known doctor's Zhang Zhongjing is pointed out in " Treatise on Febrile Diseases is distinguished the YANG MING syndrome arteries and veins and controls ": " YANG MING syndrome, from sweating, if diaphoresis, the normal urination person, this be an exhausting the body fluid in the interior, though under the hard purgative shouldn, suitable honey suppository and logical it, as if soil melon root and big Fel Sus domestica, all can be and lead." this shows that Zhong Jing clysmata the earliest only is used for the treatment of exhausting the body fluid in the interior, so that dry and astringent being difficult to resolve of stool scleroma, its mechanism of action is the heat clearing away of a surname's gas, loosing the bowel to relieve constipation.The modern Chinese medicine enema,retention is constantly to grow up on the basis of Zhong Jing moving the bowels with honey suppository.In the department of pediatrics clinical practice, children's's oral Chinese medicine difficulty, taste are subject to the characteristics that the product of bitter cold are hindered, and withdrawing the previous remark takes traditional Chinese medicine treats multiple disease for herbal retention enema, obtains better effects.

Summary of the invention

The purpose of this invention is to provide a kind of: the Chinese medicine and the using method thereof of the treatment acute bacterial dysentery in children that expense is cheap, effect is splendid.

The technical scheme that solves its technical problem employing is: herbal enema agent of the present invention is made up of following materials of weight proportions: Radix Glycyrrhizae 6, the Radix Pulsatillae 15, Radix Codonopsis 16, the Rhizoma Atractylodis Macrocephalae 12, Poria 18, Fructus Crataegi 5, Cortex Fraxini 9, Cortex Phellodendri 4, Rhizoma Coptidis 1, Flos Sophorae 6, Fructus Amomi 1, Radix Angelicae Sinensis 12, Herba Portulacae 15, the Radix Aucklandiae 4, Semen Arecae Prepareta 10, Radix Sanguisorbae 2, the Radix Aucklandiae 2, Pericarpium Citri Reticulatae 5, Endothelium Corneum Gigeriae Galli 2, Radix Stellariae 8, Radix Puerariae 5.

Beneficial effect: the present invention has adopted such scheme, and the material that makes up a prescription in the prescription all uses natural Chinese herbal medicines, adds that then traditional concocting method is made, material is easily got, prescription and preparation method are simple, and preparation medicine expense is cheap, has reached purpose of the present invention.This Chinese herbal medicine compatibility is simple, employed medicine uses natural herbal fully in the pharmaceutical formulation, it is convenient to get, use, it is good to take therapeutic effect, and drug price is cheap, can adapt to the people that live in away from small towns, outlying village especially and use, cheap to people's medical expense of suffering from the acute bacterial dysentery in children disease, solved because family income is low, living in penury, the locality lacks the problem that medical condition is cured the disease.

The specific embodiment

Embodiment:

Herbal enema agent preparation process of the present invention: Radix Glycyrrhizae 6, the Radix Pulsatillae 15, Radix Codonopsis 16, the Rhizoma Atractylodis Macrocephalae 12, Poria 18, Fructus Crataegi 5, Cortex Fraxini 9, Cortex Phellodendri 4, Rhizoma Coptidis 1, Flos Sophorae 6, Fructus Amomi 1, Radix Angelicae Sinensis 12, Herba Portulacae 15, the Radix Aucklandiae 4, Semen Arecae Prepareta 10, Radix Sanguisorbae 2, the Radix Aucklandiae 2, Pericarpium Citri Reticulatae 5, Endothelium Corneum Gigeriae Galli 2, Radix Stellariae 8, Radix Puerariae 5.

Above-mentioned each component is made the herbal enema agent according to a conventional method, finishes by following step successively:

1) decoct: above-mentioned all medicines are put into marmite, add hydrology fire by 1: 3 of crude drug gross weight and decoct, boiled back 30 minutes, medicinal liquid is leached, 1: 2 by the crude drug gross weight adds the fiery decoction of the hydrology again, boils back 20 minutes, and medicinal liquid is leached;

2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing;

3) sterilization: the medicinal liquid bottle was put into pressure cooker sterilization 30 minutes, and by medicine liquid volume: the ratio of uncooked garlic juice is 50: 1, and adding uncooked garlic juice mix homogeneously promptly gets Chinese medicine medicine enema of the present invention.

Diagnostic criteria: with reference to " traditional Chinese medical science disease diagnosis criterion of therapeutical effect ", morbidity is in summer and autumn, have the unclean food of feed or with bacillary dysentery contact patients history; Clinical manifestation is heating, stomachache, diarrhoea, tenesmus and with mucus pus and blood disease, and left lower quadrant has obvious tenderness; The stool microscopy: visible leukocyte or pus cell and erythrocyte, and macrophage is arranged, cultivate the Shigella positive for bacteria.

Therapeutic process:

Therapeutic Method

Case is selected: observe case totally 148 examples, be the court's outpatient service acute bacillary dysentery infant, clinical manifestation is heating, stomachache, diarrhoea, tenesmus and with mucus pus and blood disease, and left lower quadrant has obvious tenderness; The stool microscopy: visible leukocyte or pus cell and erythrocyte, and macrophage is arranged, cultivate the Shigella positive for bacteria.

Be divided into three groups at random, wherein 60 examples are organized in treatment, wherein male 42 examples, women 18 examples; Age) 2-5 year, average 3.5 years old; 1: 48 example of matched group, wherein male 28 examples, women 20 examples; Age) 2-5 year, average 3.4 years old.2: 40 examples of matched group, wherein male 22 examples, women 18 examples; Age) 2-5 year, average 3.3 years old.All cases were not all used other antibiotic medicine before treatment.Three groups of ages, sex, symptom, sign, stool are cultivated positive rate and learn the processing there was no significant difference by statistics, have comparability.Matched group 1 is selected the compound indigowoad leaf injection for use, and pharmaceutcal corporation, Ltd produces by Wanrong three nine-day periods after the winter solstice, and 15 days is a course of treatment, and every day, coloclysis twice, divides each coloclysis of morning and evening once, irritates the 15-25 milliliter and is advisable in each 10 minutes.Matched group 2 is selected ceftazidime 50-100mg/ (kg day) for use, adds quiet of 0.9% sodium chloride or glucose dilution back.The treatment group is selected Chinese medicine composition of the present invention for use, and using method is with matched group 1.

Therapeutic outcome (1) is cured: transference cure, and the stool microscopy is normal, and stool is cultivated continuous 3 Shigella antibacterial feminine genders; (2) take a turn for the better: transference cure or alleviate, the stool microscopy is normal, and stool is cultivated dysentery bacterium and turns out cloudy or do not turn out cloudy; (3) do not heal: clinical symptoms and stool microscopy do not have improvement.

The therapeutic effect that adopts Chinese medicine composition of the present invention is referring to table 1

Two groups of clinical therapeutic efficacies relatively, referring to table 2:

Group	Cure	Take a turn for the better	Do not heal
				Treatment group (n=60)	53(88.3％)＊	7(11.7％)	0
Matched group 1 (n=48)	30(62.5％)	11(22.9％)	7(14.6％)
				Matched group 2 (n=40)	29(72.5％)	8(20％)	3(7.5％)

Annotate: compare P＜0.01 with matched group

Points for attention: during the operation coloclysis, the anus place only need outer be coated with a glycerol or liquid Paraffin oil gets final product, and action must be brisk during coloclysis, women's infant is sure not to insert vagina, and the injection position is best with the chest and knee position, injection will be at the uniform velocity, slowly, irritated the 15-25 milliliter and be advisable in 10 minutes.If infant body temperature＞39. ℃, surpassing 30 minutes body temperature after the coloclysis does not have alleviation person, should be used the Physical temperature-lowering method and note polydipsia sugar-salt-water or suckling.10 minutes endogenous cause of ill hyperpyrexia watery stool persons will repeat supplementary irrigation intestinal 1-2 time as one sees fit.

Claims (2)

1. herbal enema agent for the treatment of acute bacterial dysentery in children is characterized in that being made by following materials of weight proportions: Radix Glycyrrhizae 6, the Radix Pulsatillae 15, Radix Codonopsis 16, the Rhizoma Atractylodis Macrocephalae 12, Poria 18, Fructus Crataegi 5, Cortex Fraxini 9, Cortex Phellodendri 4, Rhizoma Coptidis 1, Flos Sophorae 6, Fructus Amomi 1, Radix Angelicae Sinensis 12, Herba Portulacae 15, the Radix Aucklandiae 4, Semen Arecae Prepareta 10, Radix Sanguisorbae 2, the Radix Aucklandiae 2, Pericarpium Citri Reticulatae 5, Endothelium Corneum Gigeriae Galli 2, Radix Stellariae 8, Radix Puerariae 5.

Above-mentioned each component is made the herbal enema agent by the method for being prepared as follows:

1) decoct: above-mentioned all medicines are put into marmite, add hydrology fire by 1: 3 of crude drug gross weight and decoct, boiled back 30 minutes, medicinal liquid is leached, 1: 2 by the crude drug gross weight adds the fiery decoction of the hydrology again, boils back 20 minutes, and medicinal liquid is leached;

2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing;

3) sterilization: the medicinal liquid bottle was put into pressure cooker sterilization 30 minutes, and by medicine liquid volume: the ratio of uncooked garlic juice is 50: 1, and adding uncooked garlic juice mix homogeneously promptly gets the herbal enema agent.

2. preparation method for preparing the herbal enema agent for the treatment of acute bacterial dysentery in children, it is characterized in that: described herbal enema agent comprises what following materials of weight proportions was made: Radix Glycyrrhizae 6, the Radix Pulsatillae 15, Radix Codonopsis 16, the Rhizoma Atractylodis Macrocephalae 12, Poria 18, Fructus Crataegi 5, Cortex Fraxini 9, Cortex Phellodendri 4, Rhizoma Coptidis 1, Flos Sophorae 6, Fructus Amomi 1, Radix Angelicae Sinensis 12, Herba Portulacae 15, the Radix Aucklandiae 4, Semen Arecae Prepareta 10, Radix Sanguisorbae 2, the Radix Aucklandiae 2, Pericarpium Citri Reticulatae 5, Endothelium Corneum Gigeriae Galli 2, Radix Stellariae 8, Radix Puerariae 5.Its preparation method may further comprise the steps: 1) decoct: above-mentioned all medicines are put into marmite, add the fiery decoction of the hydrology by 1: 3 of crude drug gross weight, boiled back 30 minutes, medicinal liquid is leached, by the crude drug gross weight 1: 2 adds the decoction of hydrology fire again, boils back 20 minutes, and medicinal liquid is leached;

2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing;

3) sterilization: the medicinal liquid bottle was put into pressure cooker sterilization 30 minutes, and by medicine liquid volume: the ratio of uncooked garlic juice is 50: 1, and adding uncooked garlic juice mix homogeneously promptly gets above-mentioned herbal enema agent.