CN104666651B - A kind of medicament for the treatment of cervical hypertrophy - Google Patents
A kind of medicament for the treatment of cervical hypertrophy Download PDFInfo
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- CN104666651B CN104666651B CN201510063401.6A CN201510063401A CN104666651B CN 104666651 B CN104666651 B CN 104666651B CN 201510063401 A CN201510063401 A CN 201510063401A CN 104666651 B CN104666651 B CN 104666651B
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of medicament for the treatment of cervical hypertrophy, it is made up of the material of following weight portion: Herba Stylophori Lasiocapi 1-10 part, selaginella delicatula Alston 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Glycyrrhizae 1-10 part, Herba Corydalis Bungeanae 10-20 part, Radix Cyathulae 1-10 part, Radix Morindae Officinalis 1-10 part, Cortex toonae sinensis radicis 10-20 part, Periostracum Cicadae 1-10 part, sand Fructus Foeniculi 10-20 part, Folium ilicis serratae 1-10 part, Herba Phtheirospermi Japonici 10-20 part, Herba Monochoriae Korsakowii 1-10 part, close flowers and plants 10-20 part, Calendula arvensis L. 1-10 part, Ramulus et Folium Tamaricis 5-15 part, Fructus polygoni tinctorii 1-10 part, Syringa oblata Lindl. 5-15 part, Flos Woodfordiae Fruticosae 10-20 part, Semen Aesculi 1-10 part, Herba Parnassiae foliosae 10-20 part.Pharmaceutical treatment cervical hypertrophy Be very effective of the present invention, clinic application and popularization.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of cervical hypertrophy.
Background technology
Cervical hypertrophy is due to pathogenic infection cervical mucosals such as mycoplasma, chlamydia, antibacterial, viruses, such that cervix uteri is congested, edema, caused by cervix gland and interstitial generation hypertrophy.Uterine cavity blood stasis, ovarian dysfunction also can cause cervical hypertrophy.Its main clinic symptoms comprises that vaginal secretions increases, waist and sacrum pain, lower abdomen pendant rises, sexual life is hemorrhage.Delay the state of an illness or malpractice possibility up concurrent endometritis, fallopian tube adhesion, oophoritis etc., severe patient can cause sterility and infertility or cervical cancer, affects normal physiological period and family life.
Doctor trained in Western medicine takes Drug therapy or naturopathy for the treatment of cervical hypertrophy more.Drug therapy gives antibiotic medicine more, such as Compound Tinidazole medicine film and policresulen class medicine etc.; Naturopathy comprises electricity and presses treatment, cold therapy, laser therapy, micro-wave therapeutic etc.The former easily causes the side effect such as drug resistance, hepar damnification, and latter needs special instrument and equipment and professional operator, and may cause that cervical canal is narrow after treatment, adhesion etc.And the traditional Chinese medical science is mainly through determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, imposes the therapies such as invigorating the spleen and benefiting QI, nourishing kidney yin, clearing away heat-damp and promoting diuresis more, and have no side effect, compare doctor trained in Western medicine more safe and reliable.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of cervical hypertrophy.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of cervical hypertrophy, it is made up of the material of following weight portion: Herba Stylophori Lasiocapi 1-10 part, selaginella delicatula Alston 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Glycyrrhizae 1-10 part, Herba Corydalis Bungeanae 10-20 part, Radix Cyathulae 1-10 part, Radix Morindae Officinalis 1-10 part, Cortex toonae sinensis radicis 10-20 part, Periostracum Cicadae 1-10 part, sand Fructus Foeniculi 10-20 part, Folium ilicis serratae 1-10 part, Herba Phtheirospermi Japonici 10-20 part, Herba Monochoriae Korsakowii 1-10 part, close flowers and plants 10-20 part, Calendula arvensis L. 1-10 part, Ramulus et Folium Tamaricis 5-15 part, Fructus polygoni tinctorii 1-10 part, Syringa oblata Lindl. 5-15 part, Flos Woodfordiae Fruticosae 10-20 part, Semen Aesculi 1-10 part, Herba Parnassiae foliosae 10-20 part.
Preferably, the medicament for the treatment of cervical hypertrophy of the present invention is made up of the material of following weight portion: Herba Stylophori Lasiocapi 8 parts, selaginella delicatula Alston 15 parts, Radix Paeoniae Rubra 15 parts, 8 parts, Radix Glycyrrhizae, Herba Corydalis Bungeanae 15 parts, Radix Cyathulae 6 parts, Radix Morindae Officinalis 5 parts, Cortex toonae sinensis radicis 15 parts, Periostracum Cicadae 8 parts, 15 parts, sand Fructus Foeniculi, Folium ilicis serratae 5 parts, Herba Phtheirospermi Japonici 12 parts, Herba Monochoriae Korsakowii 6 parts, close flowers and plants 12 parts, Calendula arvensis L. 10 parts, Ramulus et Folium Tamaricis 10 parts, Fructus polygoni tinctorii 5 parts, Syringa oblata Lindl. 10 parts, Flos Woodfordiae Fruticosae 15 parts, Semen Aesculi 8 parts, Herba Parnassiae foliosae 12 parts.
More preferably, described medicament can be tablet, dispersible tablet, capsule, soft capsule, ointment or suppository.
The present invention also provides the purposes of compositions in the medicine of preparation treatment cervical hypertrophy, described compositions is made up of the material of following weight portion: Herba Stylophori Lasiocapi 1-10 part, selaginella delicatula Alston 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Glycyrrhizae 1-10 part, Herba Corydalis Bungeanae 10-20 part, Radix Cyathulae 1-10 part, Radix Morindae Officinalis 1-10 part, Cortex toonae sinensis radicis 10-20 part, Periostracum Cicadae 1-10 part, sand Fructus Foeniculi 10-20 part, Folium ilicis serratae 1-10 part, Herba Phtheirospermi Japonici 10-20 part, Herba Monochoriae Korsakowii 1-10 part, close flowers and plants 10-20 part, Calendula arvensis L. 1-10 part, Ramulus et Folium Tamaricis 5-15 part, Fructus polygoni tinctorii 1-10 part, Syringa oblata Lindl. 5-15 part, Flos Woodfordiae Fruticosae 10-20 part, Semen Aesculi 1-10 part, Herba Parnassiae foliosae 10-20 part.
Preferably, described compositions is made up of the material of following weight portion: Herba Stylophori Lasiocapi 8 parts, selaginella delicatula Alston 15 parts, Radix Paeoniae Rubra 15 parts, 8 parts, Radix Glycyrrhizae, Herba Corydalis Bungeanae 15 parts, Radix Cyathulae 6 parts, Radix Morindae Officinalis 5 parts, Cortex toonae sinensis radicis 15 parts, Periostracum Cicadae 8 parts, 15 parts, sand Fructus Foeniculi, Folium ilicis serratae 5 parts, Herba Phtheirospermi Japonici 12 parts, Herba Monochoriae Korsakowii 6 parts, close flowers and plants 12 parts, Calendula arvensis L. 10 parts, Ramulus et Folium Tamaricis 10 parts, Fructus polygoni tinctorii 5 parts, Syringa oblata Lindl. 10 parts, Flos Woodfordiae Fruticosae 15 parts, Semen Aesculi 8 parts, Herba Parnassiae foliosae 12 parts.
More preferably, described medicine can be tablet, dispersible tablet, capsule, soft capsule, ointment or suppository.
In the present compositions, selaginella delicatula Alston, Herba Parnassiae foliosae, Fructus polygoni tinctorii are monarch drug; Herba Stylophori Lasiocapi, Radix Paeoniae Rubra, Herba Corydalis Bungeanae, Radix Morindae Officinalis, Cortex toonae sinensis radicis, sand Fructus Foeniculi, Syringa oblata Lindl. are ministerial drug; Radix Cyathulae, Periostracum Cicadae, Folium ilicis serratae, Herba Phtheirospermi Japonici, Herba Monochoriae Korsakowii, close flowers and plants, Calendula arvensis L., Ramulus et Folium Tamaricis, Flos Woodfordiae Fruticosae, Semen Aesculi are adjuvant drug; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.
Medicament of the present invention is turbid based on dampnessization, resolving depression of regulating the flow of vital energy, be aided with heat-clearing and toxic substances removing, QI invigorating invigorating middle warmer, spleen reinforcing is soothing the liver, removing dampness leukorrhagia stopping, eliminating evil dehumidifying, warming the meridian can warm up liver, and have effect of certain sterilizing and itch-relieving, treatment cervical hypertrophy Be very effective, clinic application and popularization.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modification that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
The preparation of embodiment medicament of the present invention
For suppository, the step of preparation process of medicament of the present invention is as follows:
(1) Herba Stylophori Lasiocapi 80 grams, selaginella delicatula Alston 150 grams, Radix Paeoniae Rubra 150 grams, 80 grams, Radix Glycyrrhizae, Herba Corydalis Bungeanae 150 grams, Radix Cyathulae 60 grams, Radix Morindae Officinalis 50 grams, Cortex toonae sinensis radicis 150 grams, Periostracum Cicadae 80 grams, 150 grams, sand Fructus Foeniculi, Folium ilicis serratae 50 grams, Herba Phtheirospermi Japonici 120 grams, Herba Monochoriae Korsakowii 60 grams, close flowers and plants 120 grams, Calendula arvensis L. 100 grams, Ramulus et Folium Tamaricis 100 grams, Fructus polygoni tinctorii 50 grams, Syringa oblata Lindl. 100 grams, Flos Woodfordiae Fruticosae 150 grams, Semen Aesculi 80 grams, Herba Parnassiae foliosae 120 grams is taken;
(2) Herba Parnassiae foliosae, Radix Cyathulae, Ramulus et Folium Tamaricis are broken into smalls, cross 120 mesh sieves, for subsequent use;
(3) Herba Stylophori Lasiocapi, Radix Paeoniae Rubra, Radix Glycyrrhizae, selaginella delicatula Alston, Herba Corydalis Bungeanae, Folium ilicis serratae, Periostracum Cicadae, sand Fructus Foeniculi, Herba Monochoriae Korsakowii, Calendula arvensis L., Syringa oblata Lindl., Flos Woodfordiae Fruticosae, Radix Morindae Officinalis, Cortex toonae sinensis radicis, Herba Phtheirospermi Japonici, close flowers and plants, Fructus polygoni tinctorii, Semen Aesculi are put into container to add water 10 liters and soak 10 hours, then heat 3 hours under the condition of backflow, filter, make filtrate evaporate to dryness, pulverize;
(4) combining step (2) and (3) gains, add in the oleum sapii substrate of 500 grams, heating and melting, fully stir evenly, in impouring mould, mould is first coated with one deck lubricant, lubricant is the alcohol mixeding liquid of glycerol and concentration expressed in percentage by volume 95%, mixed proportion is the ethanol of 95% of 1g glycerol: 5ml, after cooling, to prune spilling part with cutter, opening mold, released by suppository, packaging, obtains required drug suppository.Obtained 100 suppositorys.
The effect of experimental example pharmaceutical treatment cervical hypertrophy of the present invention
1, physical data selects cervical hypertrophy patient 80 example, is divided into observation group 50 example and matched group 30 example.Observation group's patient age between 21-48 year, 35.6 years old mean age; Matched group patient age between 20-45 year, 32.5 years old mean age.All patients all get rid of cervical cancer, acute genital disease and systemic disease.According to table 1, symptom score is carried out to two groups of patients, wherein average 6.24 ± 1.58 points of observation group, average 5.92 ± 1.87 points of matched group before treatment.Through t check analysis, the age of two groups of patients and symptom score there are no significant difference (p>0.05).
Table 1 Symptoms index
2,3-7 days after method clean period, cleans pudendum before sleeping every night.The auxiliary drug delivery instrument of observation group's use or 1 suppository of the present invention utilizing sanitary finger-cot for holding embodiment to be prepared are delivered to vagina depths, 1 times/day.Matched group uses tinidazole suppositories (Zhengzhou Yonghe Pharmaceutical Co), 1 times/day.Within continuous 7 days, be a course for the treatment of, 2 totally 14 days courses for the treatment of of medication, period prohibitive life.
3, after 2 courses for the treatment of of evaluation index, again carry out symptom score according to table 1, and calculate therapeutic index and effective percentage.
Recovery from illness: therapeutic index >=90%; Effective: therapeutic index is 60%-89%; Take a turn for the better: therapeutic index is 20%-59%; Invalid: therapeutic index < 20%.Wherein:
Score value × 100% before therapeutic index=(before treatment the rear score value of score value-treatment)/treatment
Effective percentage=(cure+effective+take a turn for the better) number of cases/total number of cases × 100%
4, statistical method adopts statistics software SPSS17.0 to carry out data analysis.Measurement data with
represent, adopt t inspection; Enumeration data adopts x
2inspection.With P < 0.05 for difference has statistical significance.
5, result
After treatment, observation group's symptom score is 1.02 ± 0.95 points, and matched group symptom score is 2.50 ± 1.96 points, through t check analysis, two groups have significant difference.This shows that observation group's symptom takes a turn for the better and is better than matched group, and medicament of the present invention has significant advantage in treatment cervical hypertrophy.
Table 2 is below shown in two groups of efficient interpretations of result.Through x
2inspection, the effective percentage of two groups of patients after treatment has significant difference.
A table 2 liang group effective percentage compares
Note: compare with matched group, * p<0.05.
Claims (2)
1. treat the medicament of cervical hypertrophy for one kind, it is characterized in that being made up of the material of following weight portion: Herba Stylophori Lasiocapi 1-10 part, selaginella delicatula Alston 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Glycyrrhizae 1-10 part, Herba Corydalis Bungeanae 10-20 part, Radix Cyathulae 1-10 part, Radix Morindae Officinalis 1-10 part, Cortex toonae sinensis radicis 10-20 part, Periostracum Cicadae 1-10 part, sand Fructus Foeniculi 10-20 part, Folium ilicis serratae 1-10 part, Herba Phtheirospermi Japonici 10-20 part, Herba Monochoriae Korsakowii 1-10 part, close flowers and plants 10-20 part, Calendula arvensis L. 1-10 part, Ramulus et Folium Tamaricis 5-15 part, Fructus polygoni tinctorii 1-10 part, Syringa oblata Lindl. 5-15 part, Flos Woodfordiae Fruticosae 10-20 part, Semen Aesculi 1-10 part, Herba Parnassiae foliosae 10-20 part.
2. the medicament for the treatment of cervical hypertrophy according to claim 1, it is made up of the material of following weight portion: Herba Stylophori Lasiocapi 8 parts, selaginella delicatula Alston 15 parts, Radix Paeoniae Rubra 15 parts, 8 parts, Radix Glycyrrhizae, Herba Corydalis Bungeanae 15 parts, Radix Cyathulae 6 parts, Radix Morindae Officinalis 5 parts, Cortex toonae sinensis radicis 15 parts, Periostracum Cicadae 8 parts, 15 parts, sand Fructus Foeniculi, Folium ilicis serratae 5 parts, Herba Phtheirospermi Japonici 12 parts, Herba Monochoriae Korsakowii 6 parts, close flowers and plants 12 parts, Calendula arvensis L. 10 parts, Ramulus et Folium Tamaricis 10 parts, Fructus polygoni tinctorii 5 parts, Syringa oblata Lindl. 10 parts, Flos Woodfordiae Fruticosae 15 parts, Semen Aesculi 8 parts, Herba Parnassiae foliosae 12 parts.
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| CN201510063401.6A CN104666651B (en) | 2015-02-06 | 2015-02-06 | A kind of medicament for the treatment of cervical hypertrophy |
| CN201510481410.7A CN104983954A (en) | 2015-02-06 | 2015-02-06 | Medicament for treating cervical hypertrophy |
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| CN201510063401.6A CN104666651B (en) | 2015-02-06 | 2015-02-06 | A kind of medicament for the treatment of cervical hypertrophy |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101791377A (en) * | 2010-04-12 | 2010-08-04 | 汤永顺 | Traditional Chinese medicine preparation for post-operation rehabilitation of cervicitis and cervical hypertrophy |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101791377A (en) * | 2010-04-12 | 2010-08-04 | 汤永顺 | Traditional Chinese medicine preparation for post-operation rehabilitation of cervicitis and cervical hypertrophy |
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| CN104983954A (en) | 2015-10-21 |
| CN104666651A (en) | 2015-06-03 |
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