CN102973876B - Drug for treating pathological leukorrhagia - Google Patents
Drug for treating pathological leukorrhagia Download PDFInfo
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- CN102973876B CN102973876B CN201310001196.1A CN201310001196A CN102973876B CN 102973876 B CN102973876 B CN 102973876B CN 201310001196 A CN201310001196 A CN 201310001196A CN 102973876 B CN102973876 B CN 102973876B
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Abstract
The invention discloses a drug for treating pathological leukorrhagia, and belongs to the field of traditional Chinese medicines. The effective constituents of the drug comprise the following raw materials in parts by weight: 60-80 parts of liquorice, 50-70 parts of platycodon grandiflorum, 45-60 parts of mantis egg-case, 40-55 parts of polygonum multiflorum, 35-50 parts of sargent gloryvine, 28-42 parts of fructus amomi, 22-36 parts of dandelion, 18-30 parts of cortex ailanthic, 15-25 parts of rhizoma cimicifugae, 10-22 parts of dark plum, 6-15 parts of rhizoma picrorhizae and 3-12 parts of rangoon creeper fruit. According to the invention, the raw materials are excellent, the monarch and ministerial materials complement each other for pathological mechanisms such as spleen and kidney deficiency, damp-heat accumulation, phlegm-damp invasion, vital-energy activity blockage and the like based on the purposes of regulating menstruation and keeping beauty from the improvements on the vitality and the immunity of an organism so as to achieve the effects of tonifying spleen, reinforcing kidney, converging, arresting leucorrhea, clearing away heat, promoting diuresis, dispelling wind and reinforcing vital energy; and the drug has a very good effect for treating the pathological leukorrhagia caused by various reasons through clinic verification.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine that is used for the treatment of pathologic leukorrhagia.
Background technology
Leukorrhagia is department of obstetrics and gynecology modal symptoms clinically, the increase of general reference vaginal secretions.In the patient of main suit's leukorrhagia, some is physiological leukorrhagia, or the normal cervix liquid that falls, or the vaginal epithelial cell normally coming off, these all belong to normal physiological leucorrhoea grow in quantity, and the color, matter, the amount no exceptions that need only leucorrhea change, and need not cross multiprocessing.
The leukorrhagia causing for gynaecopathia, ought to cause medical worker's attention clinically.According to analyses such as the color of leucorrhea, matter, amount, stink and symptoms, it is generally acknowledged that the gynaecopathia that causes leukorrhagia has following a few class: one, pathogenic infection causes leukorrhagia; Two, trichomonas vaginitis infects and causes leukorrhagia; Three, cervical disease causes leukorrhagia, and the laceration of childbirth or the change of gonadal hormone or sexual behaviour cause cervix uteri inflammation; Four, chronic pelvic inflammatory disease causes leukorrhagia; Five, filterable virus infects cervix uteri, vagina and external genital and causes leukorrhagia; Six, candida albicans infection causes leukorrhagia; Seven, atrophic vaginitis causes leukorrhagia, normally owing to lacking gradually estrogen in body, causes vaginal wall to become fragile and is easily subject to antibacterial infection and is inflamed, thereby causing leukorrhagia; Eight, hysteropathy causes leukorrhagia.Conventionally with the soreness of waist, lower abdomen falling inflation, stomachache, menstrual cycle shorten, amount is many, menostaxis etc.; Nine, sexually transmitted disease (STD) causes leukorrhagia; Ten, the leukorrhagia that estrogen secretion too much causes.
Under the prerequisite of clarifying a diagnosis, the treatment of pathologic leukorrhagia, normally for the processing of primary disease or special pathogen.If the pathologic leucorrhea that foreign body causes will be taken out foreign body in time, adopt if desired antibacterials, prevention and treatment Secondary cases antibacterial infect.For the sinus tract of vagina and urethra or rectum existence, excision is best radical cure way.If microscopy alleged occurrence trichomonacide, Drug therapy is more common treatment means, such as common drug metronidazole, for nitre Cuo etc.To sum up, the therapeutic modality of modern medicine to leukorrhagia, for the symptomatic treatment of constitutional or specific disease substance, has great expectations of and eliminates pathogenic bacterium to cure leukorrhagia.Medication effect is highly significant in a short time, but pathogenic bacterium are not unique inducements of pathologic leukorrhagia, the leukorrhagia onset that therefore Therapeutic Method of modern medicine only causes pathogenic bacterium, virus.
Traditional Chinese medical theory it is generally acknowledged, leukorrhagia symptom results from body immunity and declines, and oneself adjusts scarce capacity.The base reason of causing a disease mainly contains: one, and the spleen damage of suffering from a deficiency of the kidney, turbid damp is dirty; Two, the damp-heat accumulation part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels; Three, wet heat-transformation, retardance mechanism of qi, the damp invasion of lower energizer of accumulateing; Four, a little less than deficiency of kidney-QI, astringency inducing is had no right; Five, phlegm-damp bet; For these pathogenic bases reasons, should adopt targetedly spleen benefiting and strengthen kidney, convergence leukorrhagia stopping, clearing away heat-damp and promoting diuresis, solid and gas nourishes blood, dispelling wind is astringent or styptic treatment for spontaneous sweating prescription, fundamentally improve body vigor and immunity, so that leucorrhea recovers normal.
Summary of the invention
The invention provides a kind of medicine that is used for the treatment of pathologic leukorrhagia, have effect of spleen benefiting and strengthen kidney, convergence leukorrhagia stopping, clearing away heat-damp and promoting diuresis, dispelling wind solid and gas, cure the disease and ask source treating both the principal and secondary aspects of a disease, the leukorrhagia symptom that a variety of causes is caused all has good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine for pathologic leukorrhagia, raw material composition and the parts by weight of making described effective ingredient are:
40～55 parts of 45～60 parts of Radix Polygoni Multiflori of 50～70 parts of Ootheca Mantidiss of 60～80 parts of Radix Platycodoniss of Radix Glycyrrhizae
18～30 parts of 22～36 parts of Cortex Ailanthis of 28～42 parts of Herba Taraxacis of 35～50 parts of Fructus Amomis of Caulis Sargentodoxae
3～12 parts of 6～15 parts of Fructus Quisqualis of 10～22 parts of Rhizoma Picrorhizae of 15～25 portions of Fructus Mumes of Rhizoma Cimicifugae.
Raw material composition and the parts by weight of making described effective ingredient are:
44～52 parts of 48～58 parts of Radix Polygoni Multiflori of 55～65 parts of Ootheca Mantidiss of 65～75 parts of Radix Platycodoniss of Radix Glycyrrhizae
22～28 parts of 25～33 parts of Cortex Ailanthis of 32～38 parts of Herba Taraxacis of 38～48 parts of Fructus Amomis of Caulis Sargentodoxae
5～9 parts of 8～12 parts of Fructus Quisqualis of 14～18 parts of Rhizoma Picrorhizae of 18～22 portions of Fructus Mumes of Rhizoma Cimicifugae.
Raw material composition and the parts by weight of making described effective ingredient are:
48 parts of 53 parts of Radix Polygoni Multiflori of 60 parts of Ootheca Mantidiss of 70 parts of Radix Platycodoniss of Radix Glycyrrhizae
25 parts of 29 parts of Cortex Ailanthis of 35 parts of Herba Taraxacis of 43 parts of Fructus Amomis of Caulis Sargentodoxae
7 parts of 10 parts of Fructus Quisqualis of 16 parts of Rhizoma Picrorhizae of 20 portions of Fructus Mumes of Rhizoma Cimicifugae.
Be used for the treatment of a preparation method for the medicine of pathologic leukorrhagia, comprise following processing step:
(1) Fructus Quisqualis is fried to surperficial sallow with slow fire, after cooling, ground into powder, cross 120 order fine powders, for subsequent use.
(2) by Rhizoma Cimicifugae mixing refined honey, fry to sallow and do not touch with one's hand after, grind into powder, cross 120 order fine powders, for subsequent use.
(3) Radix Glycyrrhizae, Radix Platycodonis, Fructus Amomi, Herba Taraxaci, Cortex Ailanthi, Fructus Mume, Rhizoma Picrorhizae are put into container, add the water of octuple amount, boil rear continuation and soak 6～7 hours, get immersion; In remaining medicinal residues, add again the water of six times of amounts, boil rear continuation and soak 3～4 hours, get immersion; Merge twice gained immersion, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use.
(4) Ootheca Mantidis, Radix Polygoni Multiflori, Caulis Sargentodoxae are put into container, add the Ji Me Lao Jiu of four times of amounts, boil rear continuation and soak 3～4 hours, get immersion; In remaining medicinal residues, add again the Ji Me Lao Jiu of triplication, boil rear continuation and soak 1～2 hour, get immersion; Merge twice gained immersion, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.20～1.25, for subsequent use.
(5) by the fine powder of step (1), step (2) gained, after mixing, the thick paste making with step (3), step (4) stirs, and rapid freeze-drying, is prepared as tablet product with modern science technique.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, solution 1,002 draft poison by every means, is in harmonious proportion from medicine meritorious." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have in addition anti-gastric-ulcer, gastritis effect.
Radix Platycodonis: bitter in the mouth; Pungent; Property is put down.Return lung; Stomach warp.Lung qi dispersing; Eliminate the phlegm; Sore-throat relieving; Evacuation of pus.Cure mainly cough with copious phlegm; Laryngopharynx swelling and pain; Lung abscess vomiting pus; The full hypochondriac pain of rib; Dysentery stomachache; Uroschesis." Japan hanako materia medica " carries: " trusted subordinate's distending pain, mends five kinds of over strain, fosters the spirit of nobility for lower all gas, only cramp caused by acute vomiting and diarrhea, and evil removing is warded off temperature, tonify deficiency expectorant, and by mass in the abdomen, the evacuation of pus of nourishing blood, mends internal hemorrhage due to trauma and sore throat." modern medicine study confirms, Radix Platycodonis, except sugar content is higher, also contains abundant vitamin B1, vitamin C etc., has phlegm-dispelling functions, and can reduce the content of cholesterol, increases the secretion of cholic acid, the effect such as antipyretic, analgesia in addition, antiinflammatory, calmness in addition.
Ootheca Mantidis: sweet in the mouth; Salty; Property is put down.Return liver; Kidney; Urinary bladder channel.Controlling nocturnal emission with astringent drugs reducing urination; Reinforcing the kidney and supporting YANG.Cure mainly seminal emission; Premature ejaculation; Sexual impotence; The enuresis; Frequent micturition; Urinary incontinence; Nebulousurine; Leukorrhagia." herbal classic " carries: " main damaging the spleen and stomach, hernia abdominal mass, impotence, the raw son of benefit essence.Woman's blood closes lumbago, logical five types of stranguria, diuresis water channel.”
Modern medicine study confirms, Ootheca Mantidis can effectively improve body's hypoxia tolerance, can reinforcing the kidney and supporting YANG, and kind controlling nocturnal emission with astringent drugs reducing urination again, the turbid urine that is used for suffering from a deficiency of the kidney, leukorrhagia nebulousurine.
Radix Polygoni Multiflori: bitter in the mouth; Sweet; Puckery; Slightly warm in nature.Enter liver; Kidney channel.Nourishing the blood and yin; Loosening bowel to relieve constipation; Preventing the attack (or recurrence) of malaria; Dispel the wind; Removing toxic substances.Cure mainly blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body void; Rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid." medicine justice " carries: " the liver benefiting, holds back blood, YIN nourishing.Control waist knee joint weakness, muscles and bones is ached, and cuts intermittent fever of deficiency type, and only kidney rushes down, and except metrorrhagia, separates leukorrhagia." modern medicine study confirmation, Radix Polygoni Multiflori can obviously increase blood cell number and content of hemoglobin, reduces RBC immune complex flower rate rate, and hepatocyte DNA replication dna is had to obvious potentiation, improves the activity of superoxide dismutase in body.
Caulis Sargentodoxae: bitter in the mouth; Property is put down; Nontoxic.Enter liver; Large intestine channel.Removing toxicity for eliminating carbuncles; Promoting blood circulation and stopping pain; Expelling wind and removing dampness; Parasite killing.Cure mainly intestinal carbuncle; Dysentery; Mastalgia; Dysmenorrhea; Amenorrhea; Traumatic injury; Rheumatic arthralgia; Abdominal pain due to worm stagnation." Chinese medicinal herbal " carries: " the meridian dredging that dispels the wind, diuresis parasite killing.Control acute appendicitis, rheumatic arthralgia, leprosy, gonorrhea, ascarid stomachache." clinic study shows; Caulis Sargentodoxae decoct has stronger inhibitory action to staphylococcus aureus and group B streptococcus, to escherichia coli, Staphylococcus albus, micrococcus catarrhalis, alpha streptococcus and bacillus pyocyaneus, also has certain inhibitory action; prevent damaging intestinal adhesion; anticoagulant, increases coronary flow, suppresses thrombosis; improve plasma cAMP level; improve hypoxia-bearing capability, coronary artery dilator, dwindles myocardial infarct size.
Fructus Amomi: acrid in the mouth; Warm in nature.Enter spleen; Stomach; Kidney channel.Removing dampness appetizing; Promoting the circulation of QI to alleviate the stagnation in middle-JIAO; Warming the spleen; Antidiarrheal; Antiabortive.Cure mainly retention of damp leading to blockage of QI; Abdominal distention; Anorexia; Nausea and vomiting; Stomachache is had loose bowels; Pregnancy reactions; Frequent fetal movement." detailed outline " carries: " tonifying the lung is amusing, nourishing the stomach kidney tonifying, and reason vigour, dispelling stagnant Qi, dispelling cold fluid-retention and abdominal distension, dysphagic vomiting, only woman's metrorrhagia, except throat ability to speak superficial heat, changes copper gagger and chokes." modern medicine study confirmation, Fructus Amomi can be strengthened intestinal tube and shrink, and when heavy dose of, intestinal tube is had to inhibitory action; performance tension force reduces, and partially or completely antagonism acetylcholine, enhancement intestinal movement; obviously anticoagulant, obviously resist collagen and adrenergic fall out effect.
Herba Taraxaci: bitter in the mouth; Sweet; Cold in nature.Return liver; Stomach warp.Heat-clearing and toxic substances removing; Eliminating carbuncle eliminating stagnation.Cure mainly acute mastitis; Lung abscess; Intestinal carbuncle; Mumps; Furuncle carbuncle toxin; Conjunctival congestion and swelling pain; Cold, fever; Cough; Laryngopharynx swelling and pain; Stomach-fire; Intestinal inflammation; Dysentery; Hepatitis; Cholecystitis; Urinary tract infection; Snake bite and insect sting." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control all pyogenic infections from tumour or sore, ruined tinea skin ulcer; Dispel the wind, all sores that disappears, loose scrofula tuberculosis; Stop little having blood in stool, control the five types of stranguria difficulty in urination, sharp bladder." clinic study shows, dandelion preparation can replace antibiotics to use to a certain extent, some disease is shown to effect of broad-spectrum antibiotic, has certain antiviral functions.
Cortex Ailanthi: bitter in the mouth; Puckery; Cold in nature.Return stomach; Large intestine; The heart; Liver; Spleen; Lung meridian.Heat clearing and damp drying; Astringing intestine to stop diarrhea; Hemostasis; Leukorrhagia stopping; Parasite killing.Cure mainly and have loose bowels; Dysentery; Have blood in stool; Metrorrhagia; Bleeding hemorrhoids; Leukorrhagia; Ascariasis; Skin ulcer tinea." modern Practical Chinese medicinal " carries: " for oral administration married woman's metrorrhagia and postpartum hemorrhage, metritis, enteritis, bloody dysentery, enterorrhagia, bladder and urethra inflammation, the gonorrhea etc. controlled, have that antiinflammatory, system are secreted, the merit of hemostasis; The illness of training the mind dysmenorrhoea and liver, spleen etc. again." modern medicine study confirms; Cortex Ailanthi decoct has obvious inhibitory action to shigella flexneri, Song's Shigella flexneri and escherichia coli; contained ailanthinone and Ramulus Et Folium Picrasmae have antitumor action, is used for clinically treating acute bacillary dysentery, amebic dysentery, has blood in stool, ulcer, ascariasis and cervical cancer.
Rhizoma Cimicifugae: acrid in the mouth; Sweet; Cold nature.Return lung; Spleen; Large intestine; Stomach warp.Heat-clearing and toxic substances removing; Deliver rash; Ascending up spleen-Qi and Yang.Cure mainly epidemic disease fire-toxin; Aphtha; Pharyngalgia; Macule; Headache cold and heat; Carbuncle sore tumefacting virus; Sinking of QI of middle-JIAO; Diarrhea due to hypofunction of the spleen; Heavy under chronic dysentery; Women's leukorrhagia; Metrorrhagia." detailed outline " carries: " it is up that Rhizoma Cimicifugae draws positive bright clearing heat in QI system, and it is up that Radix Bupleuri draws few positive clearing heat in QI system, and this is that natural endowment element is weak, first deficiency of vital energy is hungry and hungry full, the raw and cold internal injury of forced labour, and the key medicine of taste tying-in also." modern medicine study confirms, that Rhizoma Cimicifugae extract has is antibacterial, the effect of blood pressure lowering, inhibition cardiac muscle, decreased heart rate, and central nervous system is had to sedation.
Fructus Mume: sour in the mouth; Property is put down.Enter liver; Spleen; Lung; Kidney; Stomach; Large intestine channel.Astringing lung-QI and relieving cough; Relieving diarrhea with astringents; Hemostasis; Promote the production of body fluid; Relieving colic caused by ascaris.Cure mainly chronic cough; Deficiency-heat excessive thirst; Chronic malaria; Chronic diarrhea; Dysentery; Have blood in stool; Hematuria; Metrorrhagia; Ascariasis of biliary tract stomachache; Vomiting; Ancylostomiasis." detailed outline " carries: " astringing intestine to stop diarrhea of astringing the lung, controls chronic cough, dysentery, and regurgitation is dysphagic, ascariasis of biliary tract vomiting and diarrhea, detumescence, gushes expectorant, and parasite killing is separated ichthyotoxin, horse mump, sulfur poison." modern medicine study confirmation; Fructus Mume has obvious antibacterial action; dysentery bacterium, bacillus pyocyaneus, Bacillus typhi, escherichia coli, tubercule bacillus, Bacillus proteus, staphylococcus aureus, messy vibrio and various fungus are all had to inhibitory action; and can stimulate the hormonal secretion of the parotid gland; and clearization blood, strengthens metabolic function.
Rhizoma Picrorhizae: bitter in the mouth; Cold in nature.Return liver; Stomach; Large intestine channel.Reducing the asthenic fever; Infantile malnutrition with fever disappears; Heat clearing and damp drying; Eliminating fire and detoxication.Cure mainly deficiency of YIN hectic fever due to YIN-deficiency; Hectic fever night sweat; Children's's infantile malnutrition; Damp-heat dysentery; Jaundice; Spit blood; Epistaxis; Conjunctival congestion and swelling pain; Carbuncle skin infection; Hemorrhoid toxic swelling." Kaibao Bencao " carries: " main chronic dysentery becomes infantile malnutrition, typhoid cough, and pyrexial malaria, bone heat, reason waist kidney, removes polyhidrosis around the external genitals, pediatric epilepsy scared, cold and heat, not lower food, cholera dysentery." modern medicine study proves, Rhizoma Picrorhizae have significantly protect the liver, choleretic effect, multiple fungus is all had to inhibitory action in various degree, there is to contraction in uterus, heart is had to inhibitory action.
Fructus Quisqualis: sweet in the mouth; Warm in nature, slightly poisonous.Return spleen; Stomach warp.Parasite killing; Removing food stagnancy; Spleen invigorating.Cure mainly ascarid stomachache; Infantile malnutrition; Breast food is stagnated; Abdominal distention; Dysentery.Compendium of Material Medica is carried: " strengthening the spleen and stomach, except deficiency-heat." modern medicine study confirmation, the contained sour potassium of Fructus Quisqualis has obvious insecticidal action, and ascarid, pinworm and all kinds of fungus are all had to obvious inhibitory action.
The present invention compared with prior art, has following beneficial effect:
Prescription of the present invention is superior, start with from improving body vigor and immunity, support Rong Weiyao with regulating menstruation, for the spleen pathogenic base such as damage, damp-heat accumulation, phlegm-damp bet, the mechanism of qi retardance reason of suffering from a deficiency of the kidney, multiple medical material the monarch and his subjects help mutually, effect of asking spleen benefiting and strengthen kidney, convergence leukorrhagia stopping, clearing away heat-damp and promoting diuresis, dispelling wind solid and gas, pathologic leukorrhagia many reasons being caused through clinical verification has fabulous curative effect.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of effective ingredient of the present invention are:
Radix Glycyrrhizae 75g Radix Platycodonis 65g Ootheca Mantidis 56g Radix Polygoni Multiflori 52g
Caulis Sargentodoxae 46g Fructus Amomi 38g Herba Taraxaci 32g Cortex Ailanthi 28g
Rhizoma Cimicifugae 23g Fructus Mume 18g Rhizoma Picrorhizae 12g Fructus Quisqualis 10g.
The processing step of process for preparing medicine of the present invention is:
(1) Fructus Quisqualis is fried to surperficial sallow with slow fire, after cooling, ground into powder, cross 120 order fine powders, for subsequent use.
(2) by Rhizoma Cimicifugae mixing refined honey, fry to sallow and do not touch with one's hand after, grind into powder, cross 120 order fine powders, for subsequent use.
(3) Radix Glycyrrhizae, Radix Platycodonis, Fructus Amomi, Herba Taraxaci, Cortex Ailanthi, Fructus Mume, Rhizoma Picrorhizae are put into container, add the water of octuple amount, boil rear continuation and soak 6～7 hours, get immersion; In remaining medicinal residues, add again the water of six times of amounts, boil rear continuation and soak 3～4 hours, get immersion; Merge twice gained immersion, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use.
(4) Ootheca Mantidis, Radix Polygoni Multiflori, Caulis Sargentodoxae are put into container, add the Ji Me Lao Jiu of four times of amounts, boil rear continuation and soak 3～4 hours, get immersion; In remaining medicinal residues, add again the Ji Me Lao Jiu of triplication, boil rear continuation and soak 1～2 hour, get immersion; Merge twice gained immersion, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.20～1.25, for subsequent use.
(5) by the fine powder of step (1), step (2) gained, after mixing, the thick paste making with step (3), step (4) stirs, and rapid freeze-drying, is prepared as tablet product with modern science technique.
Usage and dosage: adult every day 3 times, each 0.5g～1.5g, patient with severe symptoms every day 4 times, each 0.8g～1.6g, after meal with warm water delivery service, 5 days is a course for the treatment of, common 3～4 onsets course for the treatment of.
Embodiment 2
Raw material composition and the weight of effective ingredient of the present invention are:
Radix Glycyrrhizae 70g Radix Platycodonis 60g Ootheca Mantidis 53g Radix Polygoni Multiflori 48g
Caulis Sargentodoxae 43g Fructus Amomi 35g Herba Taraxaci 29g Cortex Ailanthi 25g
Rhizoma Cimicifugae 20g Fructus Mume 16g Rhizoma Picrorhizae 10g Fructus Quisqualis 7g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the parts by weight of effective ingredient of the present invention are:
Radix Glycyrrhizae 65g Radix Platycodonis 55g Ootheca Mantidis 48g Radix Polygoni Multiflori 43g
Caulis Sargentodoxae 38g Fructus Amomi 32g Herba Taraxaci 25g Cortex Ailanthi 22g
Rhizoma Cimicifugae 18g Fructus Mume 15g Rhizoma Picrorhizae 9g Fructus Quisqualis 5g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection
The routine clinical observation of pathologic leukorrhagia patient 70 of selecting my institute or outer court to make a definite diagnosis, patient is divided into two groups at random.Treatment group 35 examples, wherein pathogenic bacteria virus is caused a disease because of patient's 18 examples, and pelvic inflammatory disease is caused a disease because of patient's 7 examples, hyperestrogenism or not enough leukorrhagia patient 4 examples, foreign body is invaded inflammation and is caused a disease because of patient's 4 examples, and pregnancy period gestation is caused a disease because of patient's 2 examples.Matched group 35 examples, wherein pathogenic bacteria virus is caused a disease because of patient's 14 examples, and pelvic inflammatory disease is caused a disease because of patient's 10 examples, hyperestrogenism or not enough causing a disease because of patient's 6 examples, foreign body is invaded inflammation and is caused a disease because of patient's 3 examples, too much patient's 2 examples of pregnancy period pregnant leukorrhagia.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.
2, treatment group patient takes medicine of the present invention, adult every day 3 times, and each 0.5g～1.5g, the patient that is in a bad way adds 1 every day, and dosage is enlarged to 0.8g～1.6g, within 5 days, is a course for the treatment of.Matched group according to the leukorrhagia of diagnosing out cause a disease because of, carry out specific aim antibiotic therapy.
3, efficacy determination:
(1) recovery from illness: leucorrhea is white, clear, and amount is normal, and without mutation, free from extraneous odour, without association symptom.
(2) take a turn for the better: leucorrhea amount reduces, and abnormal flavour alleviates, and association symptom obviously alleviates.
(3) invalid: symptom is with treating front no significant difference.
4, result
In treatment group, cure 27 examples, 5 examples that take a turn for the better, invalid 3 examples, cure rate 77.1%, total effective rate 91.4%.
In matched group, cure 12 examples, 9 examples that take a turn for the better, invalid 14 examples, cure rate 34.3%, total effective rate 60.0%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Clinical control treatment data shows, medicine of the present invention is by regulating body vigor and autoimmunity, to causing that the multiple pathogenic of leukorrhagia symptom reaches the standard-required of the primary medicine of clinical treatment leukorrhagia symptom completely because all there being fabulous curative effect, is suitable for applying clinically.
Claims (4)
1. a medicine that is used for the treatment of pathologic leukorrhagia, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
40～55 parts of 45～60 parts of Radix Polygoni Multiflori of 50～70 parts of Ootheca Mantidiss of 60～80 parts of Radix Platycodoniss of Radix Glycyrrhizae
18～30 parts of 22～36 parts of Cortex Ailanthis of 28～42 parts of Herba Taraxacis of 35～50 parts of Fructus Amomis of Caulis Sargentodoxae
3～12 parts of 6～15 parts of Fructus Quisqualis of 10～22 parts of Rhizoma Picrorhizae of 15～25 portions of Fructus Mumes of Rhizoma Cimicifugae;
The preparation method of making described medicine comprises following processing step:
(1) Fructus Quisqualis is fried to surperficial sallow with slow fire, after cooling, ground into powder, cross 120 order fine powders, for subsequent use;
(2) by Rhizoma Cimicifugae mixing refined honey, fry to sallow and do not touch with one's hand after, grind into powder, cross 120 order fine powders, for subsequent use;
(3) Radix Glycyrrhizae, Radix Platycodonis, Fructus Amomi, Herba Taraxaci, Cortex Ailanthi, Fructus Mume, Rhizoma Picrorhizae are put into container, add the water of octuple amount, boil rear continuation and soak 6～7 hours, get immersion; In remaining medicinal residues, add again the water of six times of amounts, boil rear continuation and soak 3～4 hours, get immersion; Merge twice gained immersion, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use;
(4) Ootheca Mantidis, Radix Polygoni Multiflori, Caulis Sargentodoxae are put into container, add the Ji Me Lao Jiu of four times of amounts, boil rear continuation and soak 3～4 hours, get immersion; In remaining medicinal residues, add again the Ji Me Lao Jiu of triplication, boil rear continuation and soak 1～2 hour, get immersion; Merge twice gained immersion, heating evaporation, 60 ℃ of simmer down tos
Under environment, the thick paste of relative density 1.20～1.25, for subsequent use;
(5) by the fine powder of step (1), step (2) gained, after mixing, the thick paste making with step (3), step (4) stirs, and rapid freeze-drying, is prepared as tablet product with modern science technique.
2. a kind of medicine that is used for the treatment of pathologic leukorrhagia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
44～52 parts of 48～58 parts of Radix Polygoni Multiflori of 55～65 parts of Ootheca Mantidiss of 65～75 parts of Radix Platycodoniss of Radix Glycyrrhizae
22～28 parts of 25～33 parts of Cortex Ailanthis of 32～38 parts of Herba Taraxacis of 38～48 parts of Fructus Amomis of Caulis Sargentodoxae
5～9 parts of 8～12 parts of Fructus Quisqualis of 14～18 parts of Rhizoma Picrorhizae of 18～22 portions of Fructus Mumes of Rhizoma Cimicifugae.
3. a kind of medicine that is used for the treatment of pathologic leukorrhagia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
48 parts of 53 parts of Radix Polygoni Multiflori of 60 parts of Ootheca Mantidiss of 70 parts of Radix Platycodoniss of Radix Glycyrrhizae
25 parts of 29 parts of Cortex Ailanthis of 35 parts of Herba Taraxacis of 43 parts of Fructus Amomis of Caulis Sargentodoxae
7 parts of 10 parts of Fructus Quisqualis of 16 parts of Rhizoma Picrorhizae of 20 portions of Fructus Mumes of Rhizoma Cimicifugae.
4. a preparation method for the medicine that is used for the treatment of pathologic leukorrhagia as described in claim 1-3 any one, is characterized in that: comprise following processing step:
(1) Fructus Quisqualis is fried to surperficial sallow with slow fire, after cooling, ground into powder, cross 120 order fine powders, for subsequent use;
(2) by Rhizoma Cimicifugae mixing refined honey, fry to sallow and do not touch with one's hand after, grind into powder, cross 120 order fine powders, for subsequent use;
(3) Radix Glycyrrhizae, Radix Platycodonis, Fructus Amomi, Herba Taraxaci, Cortex Ailanthi, Fructus Mume, Rhizoma Picrorhizae are put into container, add the water of octuple amount, boil rear continuation and soak 6～7 hours, get immersion; In remaining medicinal residues, add again the water of six times of amounts, boil rear continuation and soak 3～4 hours, get immersion; Merge twice gained immersion, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.10～1.15, for subsequent use;
(4) Ootheca Mantidis, Radix Polygoni Multiflori, Caulis Sargentodoxae are put into container, add the Ji Me Lao Jiu of four times of amounts, boil rear continuation and soak 3～4 hours, get immersion; In remaining medicinal residues, add again the Ji Me Lao Jiu of triplication, boil rear continuation and soak 1～2 hour, get immersion; Merge twice gained immersion, heating evaporation, 60 ℃ of simmer down tos
Under environment, the thick paste of relative density 1.20～1.25, for subsequent use;
(5) by the fine powder of step (1), step (2) gained, after mixing, the thick paste making with step (3), step (4) stirs, and rapid freeze-drying, is prepared as tablet product with modern science technique.
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| CN105327250A (en) * | 2015-10-28 | 2016-02-17 | 王丽 | Tablet for treating pathological leukorrhagia of women and preparation method thereof |
| CN112362774B (en) * | 2020-11-02 | 2023-05-16 | 山东沃华医药科技股份有限公司 | Method for measuring content of various effective components in menstruation-regulating and nourishing soup |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1286117A (en) * | 1999-12-13 | 2001-03-07 | 朱卫国 | Medicinal composition for treating pelvic inflammation |
| CN102406863A (en) * | 2011-11-22 | 2012-04-11 | 荣成市交通诊所 | Traditional Chinese medicine composition for treating leukorrheal diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1286117A (en) * | 1999-12-13 | 2001-03-07 | 朱卫国 | Medicinal composition for treating pelvic inflammation |
| CN102406863A (en) * | 2011-11-22 | 2012-04-11 | 荣成市交通诊所 | Traditional Chinese medicine composition for treating leukorrheal diseases |
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