CN104666590A - Good arthralgia treatment agent for treating wind-cold-dampness arthralgia scapulohumeral periarthritis and preparation method - Google Patents

Good arthralgia treatment agent for treating wind-cold-dampness arthralgia scapulohumeral periarthritis and preparation method Download PDF

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CN104666590A
CN104666590A CN201510051656.0A CN201510051656A CN104666590A CN 104666590 A CN104666590 A CN 104666590A CN 201510051656 A CN201510051656 A CN 201510051656A CN 104666590 A CN104666590 A CN 104666590A
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冯波
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Abstract

The invention discloses a good arthralgia treatment agent for treating wind-cold-dampness arthralgia scapulohumeral periarthritis. The good arthralgia treatment agent is mainly prepared from the following raw material medicines in parts by weight: 10-15 parts of red paeony root, 9-18 parts of peach seeds, 10-20 parts of Chinese angelica, 5-9 parts of trogopterus dung, 8-12 parts of figwort root, 9-15 parts of fruit-spike of common selfhea, 9-16 parts of tree peony bark, 8-12 parts of cuttlebone, 5-10 parts of herb of Japanese betony, 6-9 parts of carbonized sanguisorba root, 15-25 parts of root of lobed kudzuvine, 8-16 parts of garter snake, 10-20 parts of szechuan lovage rhizome, 10-20 parts of codonopsis pilosula and 3-6 parts of all-grass of poisonous buttercrp herb. The good arthralgia treatment agent disclosed by the invention has the effects of warming channels and expelling cold, and relieving swelling and easing pain, and can be used for rapidly relieving the pain of patients suffering from scapulohumeral periarthritis.

Description

Anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to anemofrigid-damp arthralgia scapulohumeral periarthritis and treat good dose of numbness and preparation method.
Background technology
Scapulohumeral periarthritis, full name is scapulohumeral periarthritis, is the soft tissue injurys such as shoulder joint Surrounding muscles, ligament, tendon, synovial bursa, joint capsule, regression and the chronic aseptic inflammation of one of the joint capsule caused and periarticular soft tissues.Inflammation causes the outer adhesion of intraarticular, thus affects the activity of shoulder joint.Its clinical manifestation is that onset is slow, and the course of disease is longer, and the course of disease is generally within 1 year, and comparatively elder can reach 1-2.Most more than 40 years old of age of onset, women's sickness rate a little more than male, and is more common in physical labourer.Because the people of about 50 years old easily suffers from this disease, so primary disease is also called bursitis of shoulder.Scapulohumeral periarthritis motherland medical science is referred to as " scapulohumeral periarthritis ", " congealed shoulder ", " bursitis of shoulder " etc., is based on shoulder arthralgia, first aches in paroxysmal, then moves a kind of commonly encountered diseases, the frequently-occurring disease of obstacle.Suffer from the patient of scapulohumeral periarthritis, conscious have cold air to enter shoulder, also has patient to feel have cold air outwards to emerge from shoulder joint inside, therefore also known as " scapulohumeral periarthritis ".After ill, shoulder joint can not be moved, frozen or solidify seemingly, therefore claims " congealed shoulder ", " scapulohumeral periarthritis ".Its lesion characteristic is extensive, and namely pain is extensive, function limitation is extensive, tenderness is extensive.Drug therapy is generally mainly take pain relieving, tranquillizer to alleviate the misery of patient, also or adopt acupuncture, massage mode, blood circulation promoting, alleviate muscular tone.
Publication No. CN 102552742 A(application number 201210006954.4) Chinese patent literature disclose the medicine of a kind of cure scapulohumeral periarthritis and rheumatism, this medicine is made up of the crude drug of following weight portion: Rhizoma Et Radix Notopterygii 9-11 part, Radix Saposhnikoviae 9-11 part, Rhizoma Atractylodis 45-55 part, Radix Clematidis 9-11 part, Radix Gentianae Macrophyllae 9-11 part, Herba Asari 18-22 part, Radix Angelicae Dahuricae 9-11 part, Rhizoma Chuanxiong 9-11 part, Cortex Cinnamomi 9-11 part, Semen Phaseoli 18-22 part, Radix Cyathulae 18-22 part, Radix Dipsaci 18-22 part, Herba Taxilli 18-22 part, Radix Codonopsis 9-11 part, Radix Glycyrrhizae 18-22 part, Semen Coicis 9-11 part, indometacin 2-3 part.Publication No. CN 102872442 A(application number 201210410880.0) Chinese patent literature disclose a kind of Chinese medicinal capsule of cure scapulohumeral periarthritis, be made up of following raw material of Chinese medicine, Colla cornus cervi, Poria, Herba speranskiae tuberculatae, Folium Artemisiae Argyi, Herba Taxilli, Rhizoma Curcumae Longae, Radix Aconiti Kusnezoffii, Olibanum, Radix Clematidis, Rhizoma Et Radix Notopterygii, Rhizoma Homalomenae, Rhizoma Zingiberis Recens, Radix Aconiti, Ramulus Cinnamomi, Herba Lycopodii, the Rhizoma Atractylodis Macrocephalae, Caulis Spatholobi, Ramulus Mori, Cortex schizophragmatis integrifolii radicis, Radix Angelicae Sinensis, Radix Paeoniae Alba, Herba Asari, Radix Stephaniae Tetrandrae, Radix Angelicae Pubescentis, Cortex erythrinae, Fructus Chaenomelis, Camphora, Fructus Aurantii, Squama Manis, Scolopendra, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Radix Puerariae, Radix Codonopsis, Herba Ephedrae.Publication No. CN 103142930 A(application number 201310071042.X) Chinese patent literature disclose the soft capsule of cure scapulohumeral periarthritis, compound capsules drug ratio is as follows: Radix Aconiti Lateralis Preparata 15%, Ramulus Cinnamomi 10%, Nidus Vespae 6%, Rhizoma Et Radix Notopterygii 6%, Radix Saposhnikoviae 6%, Rhizoma Curcumae Longae 6%, Cortex erythrinae 6%, Radix Paeoniae Rubra 6%, Radix Angelicae Sinensis 6%, Herba Epimedii 6%, Herba Asari 5%, Radix Clematidis 5%, Radix Morindae Officinalis 5%, the Radix Astragali 6%, the Rhizoma Atractylodis Macrocephalae 6%, above 15 kinds of Chinese medicine superfine grindings, evenly mixes and stirs, make soft capsule, oral 2 ~ 3 grams at every turn, every day three times; Oral hydrochloride glucosamine 0.75g simultaneously.
For the treatment of scapulohumeral periarthritis in modern medicine, taking calm analgesic drug product can only alleviate patient suffering, easily recurs, can not fundamentally cure, and part Chinese medicine preparation, because traditional Chinese medical science theory difference causes formula also to have difference, so need to improve treatment by Chinese herbs effect, further optimization of C/C composites.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take wide anemofrigid-damp arthralgia scapulohumeral periarthritis treatment good dose of the numbness of safe and applicable and preparation method.
Technical scheme of the present invention is:
Anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, is prepared from, is weight portion: Radix Paeoniae Rubra 10-15 primarily of following bulk drugs; Semen Persicae 9-18; Radix Angelicae Sinensis 10-20; Oletum Trogopterori 5-9; Radix Scrophulariae 8-12; Spica Prunellae 9-15; Cortex Moutan 9-16; Endoconcha Sepiae 8-12; Herba Stachydis Japonicae 5-10; Charred Radix Sanguisorbae 6-9; Radix Puerariae 15-25; Zaocys 8-16; Rhizoma Chuanxiong 10-20; Radix Codonopsis 10-20; Herba Ranunculi Scelerati (Radix Anemones rupicolae) 3-6.
Preferably, Radix Paeoniae Rubra 11-14; Semen Persicae 11-16; Radix Angelicae Sinensis 12-18; Oletum Trogopterori 6-8; Radix Scrophulariae 9-11; Spica Prunellae 11-13; Cortex Moutan 11-14; Endoconcha Sepiae 9-11; Herba Stachydis Japonicae 6-9; Charred Radix Sanguisorbae 7-8; Radix Puerariae 17-23; Zaocys 10-14; Rhizoma Chuanxiong 12-18; Radix Codonopsis 13-17; Herba Ranunculi Scelerati (Radix Anemones rupicolae) 4-5.
More preferably: Radix Paeoniae Rubra 12.5; Semen Persicae 13.5; Radix Angelicae Sinensis 15; Oletum Trogopterori 7; Radix Scrophulariae 10; Spica Prunellae 12; Cortex Moutan 12.5; Endoconcha Sepiae 10; Herba Stachydis Japonicae 7.5; Charred Radix Sanguisorbae 7.5; Radix Puerariae 20; Zaocys 12; Rhizoma Chuanxiong 15; Radix Codonopsis 15; Herba Ranunculi Scelerati (Radix Anemones rupicolae) 4.5.
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, and be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, add vinegar and decoct together with water (vinegar is 1:1 with the ratio of water), little fire slowly boils dry, and takes out, pounds into fritter;
(4) by other crude drug except Oletum Trogopterori, Zaocys, Endoconcha Sepiae and Herba Ranunculi Scelerati (Radix Anemones rupicolae), decontamination, to clean, be placed in marmite, water soaking 10-20 minute that adds total raw material medicine weight 7 times (preferred: to soak 12-18 minute; Be more preferably: soak 15 minutes), big fire is heated to boiling, then adds Herba Ranunculi Scelerati (Radix Anemones rupicolae), turns little fire and decocts 25-45 minute (preferably: decoct 30-40 minute; Be more preferably: decoct 35 minutes), Guan Huo, filtration collect filtrate;
(5) step (1), (2) and (3) gained crude drug are ground to form fine powder, mix homogeneously with step (4) gained filtrate, obtain decoction.
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats the preparation method of numbness good dose of decoction, and in step (3), the amount of vinegar and water is that the 8-12 of Endoconcha Sepiae weight is doubly (preferred: the weight of vinegar and water is 9-11 times of Endoconcha Sepiae weight; Be more preferably: the weight of vinegar and water is 10 times of Endoconcha Sepiae).
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, and be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) cleaned by other crude drug removing impurity except Oletum Trogopterori, Zaocys and Endoconcha Sepiae, be placed in the micro-stir-fry of little fire in pot 5 minutes, pulverize and sieve together with step (1) (2) (3) gained crude drug, mix homogeneously, obtains powder.
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats the preparation method of numbness good dose of powder, pulverizes 210-250 mesh sieve (preferred: to pulverize 220-240 mesh sieve in step (4); Be more preferably: pulverized 230 mesh sieves).
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, and be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) by other crude drug except Oletum Trogopterori, Zaocys, Endoconcha Sepiae and Herba Ranunculi Scelerati (Radix Anemones rupicolae), decontamination, to clean, be placed in marmite, soak 10-20 minute (preferred: to soak 12-18 minute; Be more preferably: soak 15 minutes), big fire is heated to boiling, then adds Herba Ranunculi Scelerati (Radix Anemones rupicolae) and step (1) (2) (3) gained crude drug, turns little fire and decocts 25-45 minute (preferably: decoct 30-40 minute; Be more preferably: decoct 35 minutes), Guan Huo, filtration collect filtrate;
(5) by step (4) gained filtrate reduced in volume, dry spraying, mix with pharmaceutical excipients, soft material processed, granulation, drying, granulate, obtain granule.
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats the preparation method of numbness good dose of granule, and in step (4), amount of water is that the 7-10 of total raw material medicine weight is doubly (preferred: amount of water is 8-9 times of total raw material medicine weight; Be more preferably: amount of water is 8.5 times of total raw material medicine weight).
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, and be made into pharmaceutically acceptable honeyed pill, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) other crude drug removing impurity except Oletum Trogopterori, Zaocys and Endoconcha Sepiae is cleaned, be placed in the micro-stir-fry of little fire in pot 5 minutes, 120 mesh sieves were pulverized together with step (1), (2) and (3) gained crude drug, made medicated powder and refined honey and water mix, pill bar, segmentation and round, dry, make honeyed pill.
Described anemofrigid-damp arthralgia scapulohumeral periarthritis treats the preparation method of numbness good dose of honeyed pill, and in step (4), the quality of refined honey is 0.3 times of medicated powder quality, and water is 0.9 times of medicated powder quality.
Anemofrigid-damp arthralgia scapulohumeral periarthritis provided by the invention treats the good agent prescription science of numbness, and preparation method is simple.In addition, its excellent part also shows:
1, the present invention is according to Chinese medical theory, monarch, choose reasonable medical material, ensures determined curative effect;
2, prescription of the present invention has the effect such as dispelling cold by warming the meridian, reducing swelling and alleviating pain, effectively alleviates malaise symptoms;
3, short treating period of the present invention, instant effect, can alleviate the misery of scapulohumeral periarthritis patient faster.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, is prepared from, every part of 4g: Radix Paeoniae Rubra 10 parts primarily of following bulk drugs, 9 parts, Semen Persicae, Radix Angelicae Sinensis 10 parts, Oletum Trogopterori 5 parts, Radix Scrophulariae 8 parts, Spica Prunellae 9 parts, Cortex Moutan 9 parts, Endoconcha Sepiae 8 parts, Herba Stachydis Japonicae 5 parts, charred Radix Sanguisorbae 6 parts, Radix Puerariae 15 parts, Zaocys 8 parts, Rhizoma Chuanxiong 10 parts, Radix Codonopsis 10 parts, Herba Ranunculi Scelerati (Radix Anemones rupicolae) 3 parts.The preparation method that above-mentioned anemofrigid-damp arthralgia scapulohumeral periarthritis treats numbness good dose of decoction is:
(1) get Oletum Trogopterori removing impurity and ash bits, heating rice vinegar is to boiling, and stifling crude drug 20 minutes, is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, Steam by water bath 35 minutes after taking out, taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) by other crude drug except Oletum Trogopterori, Zaocys, Endoconcha Sepiae and Herba Ranunculi Scelerati (Radix Anemones rupicolae), decontamination, clean, be placed in marmite, add the water soaking 15 minutes of total raw material medicine weight 7 times, big fire is heated to boiling, then adds Herba Ranunculi Scelerati (Radix Anemones rupicolae), turn little fire to decoct 35 minutes, Guan Huo, filtration collect filtrate;
(5) step (1), (2) and (3) gained crude drug are ground to form fine powder, mix homogeneously with step (4) gained filtrate, obtain decoction.
embodiment 2anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, is prepared from, every part of 4g: Radix Paeoniae Rubra 15 parts primarily of following bulk drugs, 18 parts, Semen Persicae, Radix Angelicae Sinensis 20 parts, Oletum Trogopterori 9 parts, Radix Scrophulariae 12 parts, Spica Prunellae 15 parts, Cortex Moutan 16 parts, Endoconcha Sepiae 12 parts, Herba Stachydis Japonicae 10 parts, charred Radix Sanguisorbae 9 parts, Radix Puerariae 25 parts, Zaocys 16 parts, Rhizoma Chuanxiong 20 parts, Radix Codonopsis 20 parts, Herba Ranunculi Scelerati (Radix Anemones rupicolae) 6 parts.The preparation method that above-mentioned anemofrigid-damp arthralgia scapulohumeral periarthritis treats numbness good dose of powder is:
(1) get Oletum Trogopterori removing impurity and ash bits, heating rice vinegar is to boiling, and stifling crude drug 20 minutes, is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, Steam by water bath 35 minutes after taking out, taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) other crude drug removing impurity except Oletum Trogopterori, Zaocys and Endoconcha Sepiae is cleaned, be placed in the micro-stir-fry of little fire in pot 5 minutes, pulverized 230 mesh sieves, mix homogeneously together with step (1) (2) (3) gained crude drug, obtain powder.
Model case: xxx, women, 45 years old.Medical history: patient is in feeling right shoulder pain the year before, stretch difficulty, opinionated overworking is not noted, the rear state of an illness increases the weight of gradually, the moving obstacles such as upper act, supination, abduction, the rear state of an illness of taking medicine slightly is alleviated, and after being once caught in the rain, pain is shown effect again, scorching hot pain in shoulder, affected part swelling, can not work, after carrying out examination in hospital, be diagnosed as scapulohumeral periarthritis.
Under the recommendation of friend, patient takes this example gained powder, each 3-5g, warm boiled water, one day three times seven days is a course for the treatment of, take a course for the treatment of, patient's shoulder pain alleviates to some extent, can light activity, after taking three courses for the treatment of continuously, swelling place is eliminated, substantially can be freely movable, without other uncomfortable diseases, can normally work and live.
embodiment 3anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, is prepared from, every part of 4g: Radix Paeoniae Rubra 11 parts primarily of following bulk drugs, 11 parts, Semen Persicae, Radix Angelicae Sinensis 12 parts, Oletum Trogopterori 6 parts, Radix Scrophulariae 9 parts, Spica Prunellae 11 parts, Cortex Moutan 11 parts, Endoconcha Sepiae 9 parts, Herba Stachydis Japonicae 6 parts, charred Radix Sanguisorbae 7 parts, Radix Puerariae 17 parts, Zaocys 10 parts, Rhizoma Chuanxiong 12 parts, Radix Codonopsis 13 parts, Herba Ranunculi Scelerati (Radix Anemones rupicolae) 4 parts.The preparation method that above-mentioned anemofrigid-damp arthralgia scapulohumeral periarthritis treats numbness good dose of granule is:
(1) get Oletum Trogopterori removing impurity and ash bits, heating rice vinegar is to boiling, and stifling crude drug 20 minutes, is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, Steam by water bath 35 minutes after taking out, taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) by other crude drug except Oletum Trogopterori, Zaocys, Endoconcha Sepiae and Herba Ranunculi Scelerati (Radix Anemones rupicolae), decontamination, clean, be placed in marmite, add the water soaking 15 minutes of total raw material medicine weight 8.5 times, big fire is heated to boiling, add Herba Ranunculi Scelerati (Radix Anemones rupicolae) and step (1) (2) (3) gained crude drug again, turn little fire and decoct 35 minutes, Guan Huo, filtration collect filtrate;
(5) by step (4) gained filtrate reduced in volume, dry spraying, mix with pharmaceutical excipients, soft material processed, granulation, drying, granulate, obtain granule.
Model case: xxx, male, 50 years old.Main suit: left side shoulder pain is obviously limited with activity., before three months, there is left shoulder pain, based on swelling without obvious inducement in medical history: patient is retired worker, night obviously increases the weight of, and can not carry weight, is scapulohumeral periarthritis through hospital diagnosis, adopt close, Drug therapy, poor effect, after feel that left neck and back also start to occur uncomfortable disease gradually.
Have the attitude of trying in arms, take this example gained granule, each 3-5g, warm boiled water, one day three times seven days is a course for the treatment of, after patient takes a course for the treatment of, pain obviously alleviates, and takes again two courses for the treatment of continuously, left shoulder basic activity is normal, can weight be extracted, after hospital's further consultation, cure completely, follow up a case by regular visits in two years, do not recur.
embodiment 4anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, is prepared from, every part of 4g: Radix Paeoniae Rubra 14 parts primarily of following bulk drugs, 16 parts, Semen Persicae, Radix Angelicae Sinensis 18 parts, Oletum Trogopterori 8 parts, Radix Scrophulariae 11 parts, Spica Prunellae 13 parts, Cortex Moutan 14 parts, Endoconcha Sepiae 11 parts, Herba Stachydis Japonicae 9 parts, charred Radix Sanguisorbae 8 parts, Radix Puerariae 23 parts, Zaocys 14 parts, Rhizoma Chuanxiong 18 parts, Radix Codonopsis 17 parts, Herba Ranunculi Scelerati (Radix Anemones rupicolae) 5 parts.The preparation method that above-mentioned anemofrigid-damp arthralgia scapulohumeral periarthritis treats numbness good dose of honeyed pill is:
(1) get Oletum Trogopterori removing impurity and ash bits, heating rice vinegar is to boiling, and stifling crude drug 20 minutes, is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, Steam by water bath 35 minutes after taking out, taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) other crude drug removing impurity except Oletum Trogopterori, Zaocys and Endoconcha Sepiae is cleaned, be placed in the micro-stir-fry of little fire in pot 5 minutes, 120 mesh sieves were pulverized together with step (1), (2) and (3) gained crude drug, made medicated powder and refined honey and water mix that (quality of refined honey is 0.3 times of medicated powder quality, water is 0.9 times of medicated powder weight), pill bar, segmentation and round, drying, makes honeyed pill.
Model case: xxx, women, 55 years old.Main suit: right shoulder pain, active receiving limited more than 2 years, increased the weight of three months.Medical history: patient started before 2 years to occur right shoulder pain, limitation of activity, can not go up act, can not back, and Zeng Shoufeng catches a cold, and night, pain increased the weight of, and cannot fall asleep, and there is the sensation of boring wind at scapula place, once massages, poor effect, and enters examination in hospital, and be diagnosed as scapulohumeral periarthritis.
Take this example gained honeyed pill, each 3-4, warm boiled water.One day three times, within seven days, be a course for the treatment of, after patient takes two courses for the treatment of, right shoulder pain disappears substantially, and activity freely, can carry light thing, consolidates again two courses for the treatment of, and it is completely no problem that right upper extremity is stretched after act, inward turning, horizontal position, can orthobiosis.
embodiment 5anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, is prepared from, every part of 4g: Radix Paeoniae Rubra 12.5 parts primarily of following bulk drugs, 13.5 parts, Semen Persicae, Radix Angelicae Sinensis 15 parts, Oletum Trogopterori 7 parts, Radix Scrophulariae 10 parts, Spica Prunellae 12 parts, Cortex Moutan 12.5 parts, Endoconcha Sepiae 10 parts, Herba Stachydis Japonicae 7.5 parts, charred Radix Sanguisorbae 7.5 parts, Radix Puerariae 20 parts, Zaocys 12 parts, Rhizoma Chuanxiong 15 parts, Radix Codonopsis 15 parts, Herba Ranunculi Scelerati (Radix Anemones rupicolae) 4.5 parts.The preparation method that above-mentioned anemofrigid-damp arthralgia scapulohumeral periarthritis treats numbness good dose of decoction is:
(1) get Oletum Trogopterori removing impurity and ash bits, heating rice vinegar is to boiling, and stifling crude drug 20 minutes, is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, Steam by water bath 35 minutes after taking out, taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) by other crude drug except Oletum Trogopterori, Zaocys, Endoconcha Sepiae and Herba Ranunculi Scelerati (Radix Anemones rupicolae), decontamination, clean, be placed in marmite, add the water soaking 15 minutes of total raw material medicine weight 7 times, big fire is heated to boiling, then adds Herba Ranunculi Scelerati (Radix Anemones rupicolae), turn little fire to decoct 35 minutes, Guan Huo, filtration collect filtrate;
(5) step (1), (2) and (3) gained crude drug are ground to form fine powder, mix homogeneously with step (4) gained filtrate, obtain decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Paeoniae Rubra: base is former: the root of Paeoniaceae plant peony, CHUANSHAO medicine, Paeonia obovata Maxim., hair leaf Paeonia obovata Maxim., Paeonia mairei Lévl., Paeonia anomala and tuber Radix Paeoniae.Nature and flavor: bitter; Be slightly cold.Gui Jing: liver; Spleen channel.Function cures mainly: clearing away heat and cooling blood; Blood circulation promoting and blood stasis dispelling.Main maculae caused by violent heat pathogen; Hematemesis and epistaxis; Discharging fresh blood stool; Conjunctival congestion and swelling pain; Carbuncle skin infection; Amenorrhea; Dysmenorrhea; Metrorrhagia and leukorrhagia stranguria with turbid discharge; The stagnant hypochondriac pain of the stasis of blood; Hernia abdominal mass is gathered; Injury from falling down.
Semen Persicae: nature and flavor: bitter sweet; Flat; Nontoxic.Gui Jing: the heart; Liver; Large intestine; Lung; Spleen channel.Function cures mainly: blood stasis removing and clots absorbing; Moisturize laxation.Main warp closes; Lump in the abdomen; Calentura blood-retention; Migratory arthralgia; Malaria; Traumatic injury; Swelling and pain due to blood stasis; The dry constipation of blood.
Radix Angelicae Sinensis: nature and flavor with return through sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Oletum Trogopterori: base is former: be the dry feces of flying squirrel section animal trogopterus xanthipes Milne-Edwards.Nature and flavor: bitter sweet, temperature.Gui Jing: enter liver, spleen channel.Function cures mainly: life promoting the circulation of blood pain relieving.Control all pains of trusted subordinate's vim and vigour, women's amenorrhea, postnatal blood stasis is had a pain; External treatment Serpentis, scorpion, centipete bite.Stir-fry is stopped blooding.Control metrorrhagia, menorrhagia, leucorrhea with bloody discharge is without cease.
Radix Scrophulariae: bitter in the mouth is salty, cold nature.Nontoxic.There is effect of clearing away heat and cooling blood, eliminating fire and detoxication, replenishing YIN and removing heat.Constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus is hindered for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, Tianjin.
Spica Prunellae: base is former: be the fruit ear of labiate Spica Prunellae.Nature and flavor with return through: pungent, bitter, cold.Return liver, gallbladder meridian.There is purging liver-fire, improving eyesight, effect of mass dissipating and swelling eliminating.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, acute mastitis, nodules of the breast, distending pain of the breast.
Cortex Moutan: base is former: be the root bark of ranunculaceae peony.Chemical analysis: root is containing paeonol, paeonolide, paeonolide, paeoniflorin.Still containing volatile oil 0.15 ~ 0.4% and plant sterol etc.Nature and flavor: arduous, cool.Gui Jing: enter the heart, liver, kidney channel.Function cures mainly: heat clearing away, removing heat from blood, and blood, repercussive.Control the pathogenic heat attacking blood system in febrile diseases, send out speckle, infantile convulsion, tells, is defeated in battle, has blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea, lump in the abdomen, and carbuncle and ulcer, flutters damage.
Endoconcha Sepiae: base is former: be the inner shell of black Quarry section animal needleless crow Quarry or Golden Crow Quarry.Chemical analysis: containing calcium carbonate 80 ~ 85%, conchiolin 6 ~ 7%, phlegmatic temperament 10 ~ 15%, and containing a small amount of sodium chloride, calcium phosphate, magnesium salt etc.Nature and flavor: salty, tepor.Gui Jing: enter liver, kidney channel.Dehumidifying, antacid, hemostasis, sore.Treat for stomachache acid regurgitation, tells, is defeated in battle, hematemesis, has blood in stool, bleeding not during menses, amenorrhea due to blood depletion, stomachache lump in the abdomen, intermittent fever of deficiency type dysentery, the rotten skin ulcer of the erosion of the vulva.
Herba Stachydis Japonicae: base is former: be herb or the root of labiate Herba Stachydis Japonicae, magnificent Herba Stachydis Japonicae or Herba Stachydis.Nature and flavor: acrid in the mouth; Cool in nature.Gui Jing: return lung; Stomach warp.Function cures mainly: heat-clearing and toxic substances removing; Cough-relieving sore-throat relieving; Hemostasia and detumescence.Main flu; Acute filthy disease; Consumptive lung disease; Lung abscess; Wind syndrome of head is dizzy; Pharyngalgia; Between mistake; Spit blood; Spitting of blood; Epistaxis; Metrorrhagia; Dysentery; Stranguria; Treating swelling and pain by traumatic injury.
Charred Radix Sanguisorbae: Radix Sanguisorbae: base is former: be the dry root of rosaceous plant Radix Sanguisorbae or the Radix Sanguisorbae that comes into leaves.Nature and flavor with return through: bitter, acid, puckery, be slightly cold.Return liver, large intestine channel.Function with cure mainly: cooling blood for hemostasis, removing toxic substances sore.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.Charred Radix Sanguisorbae: get pure land elm sheet, fries to surface coke black, inner sepia according to parch to black method.This product shape as Radix Sanguisorbae sheet, surface coke black, inner sepia.Tool burnt odor gas, mildly bitter flavor is puckery.
Radix Puerariae: nature and flavor: sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Cure mainly: for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Zaocys: base is former: be the entirety of Colubridae animal Zaocys removing internal organs.Nature and flavor: Gan Xian are flat.Gui Jing: " Thunder God concocts property of medicine solution ": " enter lung, spleen two warp." function cures mainly: wind-damp dispelling, the meridian dredging.Dispelling the wind and dampness pathogens insensitive impediment, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.
Rhizoma Chuanxiong: nature and flavor with return through: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: activating QI to alleviate the depression, and method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Radix Codonopsis: nature and flavor with return through: sweet, flat.Return spleen, lung meridian.Function with cure mainly: spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.
Herba Ranunculi Scelerati (Radix Anemones rupicolae): base is former: be the herb of ranunculaceae plant Herba Ranunculi Scelerati (Radix Anemones rupicolae).Chemical analysis: herb is containing procephalon father-in-law element, and eryside, 5-hydroxy tryptamine, Anemonin, also contains choline, unsaturated sterols, Galla Turcica (Galla Helepensis) phenolic tannin and flavone compound.Nature and flavor: bitter; Pungent; Cold; Poisonous.Gui Jing: the heart; Lung meridian.Function cures mainly: heat-clearing and toxic substances removing; Dispersing swelling and dissipating binds; Pain relieving; Preventing the attack (or recurrence) of malaria.Main carbuncle furuncle and phyma poison; Venom; Sucutaneous nodule scrofula; Fengshi Guanjie swells and ache; Toothache; Malaria.
test example 1gained anemofrigid-damp arthralgia scapulohumeral periarthritis of the present invention treats the clinical practice of good dose of numbness (embodiment 5):
Choose crowd: (1. more than 40 ~ 50 years old person in middle and old age, often have rheumatism attacked by the cold and evil history or trauma history according to the diagnostic criteria of scapulohumeral periarthritis.2. shoulder pain and movable pain, night increases the weight of, and can radiate in one's hands, but numbness is abnormal.3. the especially above act of shoulder mobility, abduction, inside and outside revolve limited.4. shoulder tenderness, particularly brachial biceps ditch.5. shoulder muscle spasm or amyotrophy.6. x-ray and the general discovery without exception of laboratory examination.), from Duo Jia hospital screening scapulohumeral periarthritis patient 379 example, wherein women 199 example, male 180 example, the range of age 40-70 year, the course of disease the shortest half a year, the longest is 10 years, and patient is reception test all voluntarily.
Before test, patient is divided into two groups at random, experimental group 225 example and matched group 154 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes gained decoction of the present invention, each 20-40ml, one day three times, warmly takes, and within seven days, is a course for the treatment of; Matched group uses other conventional medicines (subsides of WANTONG JINGU PIAN, scapulohumeral periarthritis, tablet for relieving rigidity of muscles and promoting blood circulation or indometacin etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: shoulder pain disappears, and shoulder joint function recovers completely; (2) effective: shoulder pain disappears substantially, shoulder joint function recovers substantially; (3) effective: shoulder pain alleviates, and shoulder joint function makes moderate progress, but still limitation of activity; (4) invalid: symptom and sign are all without improving.
Clinical effectiveness: after the treatment of four courses for the treatment of, use in the experimental group of products obtained therefrom of the present invention, shoulder pain disappears, the patient that shoulder joint function recovers completely has 132 examples (58.7%), and shoulder pain disappears substantially, shoulder joint function substantially recover patient have 64 examples (28.4%), shoulder pain alleviates, shoulder joint function makes moderate progress, but still the patient of limitation of activity has 22 examples (9.8%), and the total effective rate of known experimental group is 96.9%.The patient cured in matched group has 73 examples (47.4%), and effective patient has 29 examples (18.8%), and effective patient has routine 23(14.9%), the total effective rate of matched group is 81.1%.Experimental group product curative effect used is obviously better than matched group, and before and after treatment, the patient body situation of experimental group is significantly increased comparatively before.
Chinese medicine used in the present invention, there is the Radix Paeoniae Rubra of blood circulation promoting and blood stasis dispelling, the Semen Persicae of removing blood stasis blood stasis expelling, the Oletum Trogopterori of the enrich blood Radix Angelicae Sinensis of invigorating blood circulation, promoting the circulation of blood pain relieving, the Radix Scrophulariae of clearing away heat and cooling blood, the Spica Prunellae of mass dissipating and swelling eliminating, heat clearing away disappear become silted up Cortex Moutan, dehumidifying hemostasis Endoconcha Sepiae, the Herba Stachydis Japonicae of hemostasia and detumescence, the charred Radix Sanguisorbae of cooling blood for hemostasis, the Radix Puerariae of expelling pathogenic factors from muscles for reducing heat, the Zaocys of dispelling wind and removing obstruction in the collateral, the Rhizoma Chuanxiong of promoting blood circulation and stopping pain, the Radix Codonopsis of nourishing blood to promote the production of body fluid, the Herba Ranunculi Scelerati (Radix Anemones rupicolae) of dispersing swelling and dissipating binds, multiple medical material cooperative cooperating, drug effect is played to greatest extent, for scapulohumeral periarthritis, there is significant therapeutic effect.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. anemofrigid-damp arthralgia scapulohumeral periarthritis treats good dose of numbness, it is characterized in that, is prepared from primarily of following bulk drugs, be weight portion: Radix Paeoniae Rubra 10-15; Semen Persicae 9-18; Radix Angelicae Sinensis 10-20; Oletum Trogopterori 5-9; Radix Scrophulariae 8-12; Spica Prunellae 9-15; Cortex Moutan 9-16; Endoconcha Sepiae 8-12; Herba Stachydis Japonicae 5-10; Charred Radix Sanguisorbae 6-9; Radix Puerariae 15-25; Zaocys 8-16; Rhizoma Chuanxiong 10-20; Radix Codonopsis 10-20; Herba Ranunculi Scelerati (Radix Anemones rupicolae) 3-6.
2. anemofrigid-damp arthralgia scapulohumeral periarthritis as claimed in claim 1 treats good dose of numbness, it is characterized in that, Radix Paeoniae Rubra 11-14; Semen Persicae 11-16; Radix Angelicae Sinensis 12-18; Oletum Trogopterori 6-8; Radix Scrophulariae 9-11; Spica Prunellae 11-13; Cortex Moutan 11-14; Endoconcha Sepiae 9-11; Herba Stachydis Japonicae 6-9; Charred Radix Sanguisorbae 7-8; Radix Puerariae 17-23; Zaocys 10-14; Rhizoma Chuanxiong 12-18; Radix Codonopsis 13-17; Herba Ranunculi Scelerati (Radix Anemones rupicolae) 4-5(is preferably: Radix Paeoniae Rubra 12.5; Semen Persicae 13.5; Radix Angelicae Sinensis 15; Oletum Trogopterori 7; Radix Scrophulariae 10; Spica Prunellae 12; Cortex Moutan 12.5; Endoconcha Sepiae 10; Herba Stachydis Japonicae 7.5; Charred Radix Sanguisorbae 7.5; Radix Puerariae 20; Zaocys 12; Rhizoma Chuanxiong 15; Radix Codonopsis 15; Herba Ranunculi Scelerati (Radix Anemones rupicolae) 4.5).
3. the anemofrigid-damp arthralgia scapulohumeral periarthritis as described in as arbitrary in claim 1-2 treats good dose of numbness, and it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, add vinegar and decoct together with water (vinegar is 1:1 with the ratio of water), little fire slowly boils dry, and takes out, pounds into fritter;
(4) by other crude drug except Oletum Trogopterori, Zaocys, Endoconcha Sepiae and Herba Ranunculi Scelerati (Radix Anemones rupicolae), decontamination, to clean, be placed in marmite, water soaking 10-20 minute that adds total raw material medicine weight 7 times (preferred: to soak 12-18 minute; Be more preferably: soak 15 minutes), big fire is heated to boiling, then adds Herba Ranunculi Scelerati (Radix Anemones rupicolae), turns little fire and decocts 25-45 minute (preferably: decoct 30-40 minute; Be more preferably: decoct 35 minutes), Guan Huo, filtration collect filtrate;
(5) step (1), (2) and (3) gained crude drug are ground to form fine powder, mix homogeneously with step (4) gained filtrate, obtain decoction.
4. anemofrigid-damp arthralgia scapulohumeral periarthritis treats the preparation method of numbness good dose of decoction as claimed in claim 3, it is characterized in that, in step (3), the amount of vinegar and water is that the 8-12 of Endoconcha Sepiae weight is doubly (preferred: the weight of vinegar and water is 9-11 times of Endoconcha Sepiae weight; Be more preferably: the weight of vinegar and water is 10 times of Endoconcha Sepiae).
5. the anemofrigid-damp arthralgia scapulohumeral periarthritis as described in as arbitrary in claim 1-2 treats good dose of numbness, and it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) cleaned by other crude drug removing impurity except Oletum Trogopterori, Zaocys and Endoconcha Sepiae, be placed in the micro-stir-fry of little fire in pot 5 minutes, pulverize and sieve together with step (1) (2) (3) gained crude drug, mix homogeneously, obtains powder.
6. anemofrigid-damp arthralgia scapulohumeral periarthritis as claimed in claim 5 treats the preparation method of numbness good dose of powder, it is characterized in that, pulverizes 210-250 mesh sieve (preferred: to pulverize 220-240 mesh sieve in step (4); Be more preferably: pulverized 230 mesh sieves).
7. the anemofrigid-damp arthralgia scapulohumeral periarthritis as described in as arbitrary in claim 1-2 treats good dose of numbness, and it is characterized in that, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) by other crude drug except Oletum Trogopterori, Zaocys, Endoconcha Sepiae and Herba Ranunculi Scelerati (Radix Anemones rupicolae), decontamination, to clean, be placed in marmite, soak 10-20 minute (preferred: to soak 12-18 minute; Be more preferably: soak 15 minutes), big fire is heated to boiling, then adds Herba Ranunculi Scelerati (Radix Anemones rupicolae) and step (1) (2) (3) gained crude drug, turns little fire and decocts 25-45 minute (preferably: decoct 30-40 minute; Be more preferably: decoct 35 minutes), Guan Huo, filtration collect filtrate;
(5) by step (4) gained filtrate reduced in volume, dry spraying, mix with pharmaceutical excipients, soft material processed, granulation, drying, granulate, obtain granule.
8. anemofrigid-damp arthralgia scapulohumeral periarthritis treats the preparation method of numbness good dose of granule as claimed in claim 7, it is characterized in that, in step (4), amount of water is that the 7-10 of total raw material medicine weight is doubly (preferred: amount of water is 8-9 times of total raw material medicine weight; Be more preferably: amount of water is 8.5 times of total raw material medicine weight).
9. the anemofrigid-damp arthralgia scapulohumeral periarthritis as described in as arbitrary in claim 1-2 treats good dose of numbness, and it is characterized in that, be made into pharmaceutically acceptable honeyed pill, its preparation method is:
(1) get Oletum Trogopterori removing impurity and ash bits, heat rice vinegar to boiling, stifling crude drug 15-25 minute (preferred: to fumigate crude drug 20 minutes), is placed in parch container, and slow fire heating stir-fries to micro-dry, and taking-up is dried;
(2) get Zaocys and clean cutting, add yellow wine and infiltrate, seal vexed, take out latter Steam by water bath 30-40 minute (preferably; Steam by water bath 32-38 minute; Be more preferably: Steam by water bath 35 minutes), taking-up is dried;
(3) Endoconcha Sepiae remove impurity cleaned, the vinegar adding Endoconcha Sepiae weight 10 times decocts together with water (vinegar is 1:1 with the ratio of water), and little fire slowly boils dry, and takes out, pounds into fritter;
(4) other crude drug removing impurity except Oletum Trogopterori, Zaocys and Endoconcha Sepiae is cleaned, be placed in the micro-stir-fry of little fire in pot 5 minutes, 120 mesh sieves were pulverized together with step (1), (2) and (3) gained crude drug, made medicated powder and refined honey and water mix, pill bar, segmentation and round, dry, make honeyed pill.
10. anemofrigid-damp arthralgia scapulohumeral periarthritis as claimed in claim 9 treats the preparation method of numbness good dose of honeyed pill, it is characterized in that, in step (4), the quality of refined honey is 0.3 times of medicated powder quality, and water is 0.9 times of medicated powder quality.
CN201510051656.0A 2015-02-02 2015-02-02 Good arthralgia treatment agent for treating wind-cold-dampness arthralgia scapulohumeral periarthritis and preparation method Pending CN104666590A (en)

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