CN1537608A - Traditional Chinese medicine for treating stiffness nape and shoulder disease - Google Patents

Abstract

A Chinese medicine in the form of honeyed pills for treating cervical spondylopathy, cervical hyperplasia, cervical spondylosis, periomethritis, hyperosteogeny, lumbocrural pain, bone fracture, injury, etc is prepared from 18 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong rhizome, red peony root, rehmannia root, etc through pretreating some of them, grinding, sieving, mixing and shaping honeyed pills.

Description

A kind of Chinese medicine for the treatment of stiffness of the nape scapulohumeral periarthritis disease

Technical field: the present invention relates to Chinese medicine, particularly treat the Chinese medicine of cervical spondylosis.

Background technology: treat the cervical spondylosis Western medicine at present and be of no curative effect, and the Chinese medicine of set a broken bone disease of a great variety but cure the disease effect not significantly, cure the symptoms, not the disease, the patient also can be recurred after more.

The content of invention: overcome the deficiency that prior art exists, proposes a kind ofly to treat that cervical spondylosis, hyperosteogeny, cervical vertebra are tetanic, cervical vertebra disfiguration, cervical spondylitis, scapulohumeral periarthritis, pain in my shoulder, the Chinese medicine of diseases such as swollen thick, the muscle atrophia of two arm pain fiber crops, finger, back side of head pain, rheumatic scapulohumeral periarthritis, apathy, cervical-shoulder syndrome, hyperosteogeny, lumbago, skelalgia, backache, traumatic injury.This Chinese medicine is made by the following weight proportion raw material: Radix Angelicae Sinensis 10-16 part, Rhizoma Chuanxiong 8-12 part, Radix Paeoniae Rubra 8-14 part, Radix Rehmanniae 40-60 part, Rhizoma Polygonati Odorati 10-14 part, Radix Ophiopogonis 10-20 part, Fructus Lycii 10-20 part, Rhizoma Cimicifugae 10-16 part, Rhizoma Atractylodis 10-16 part, Radix Codonopsis 15-21 part, Radix Astragali 15-25 part, Radix Puerariae 10-20 part, Fructus Schisandrae Chinensis 10-14 part, Ramulus Cinnamomi 10-14 part, Radix Salviae Miltiorrhizae 10-14 part, Olibanum (processed) 6-10 part, Myrrha (processed) 6-10 part, Semen Strychni (processed) 15-25 part.Its production method is: Olibanum, Myrrha are deoiled, and fried Semen Strychni yellowly grinds each flavor medicine together for smalls, sieves, mixes to spare and make honeyed pill.Therefore Chinese medicine of the present invention can increase the myocardial blood circulation, the analgesic effect is arranged owing to containing Radix Angelicae Sinensis; Rhizoma Chuanxiong has sedation to the central nervous system; Radix Paeoniae Rubra contains paeoniflorin, fatty oil, benzoic acid, Radix Rehmanniae nourishing blood and hemoslasis calmness, analgesia; Rhizoma Polygonati Odorati has the merit of nourishing nourishing to heart; The blue or green winter can be improved the anti-foster power of cardiac muscle; The Rhizoma Cimicifugae function is up and calm; Rhizoma Atractylodis calmness, analgesia; The Radix Codonopsis invigorating the spleen and replenishing QI; The Radix Astragali can strengthen body immunity; Radix Puerariae yang invigorating gas, expelling pathogenic factors from muscles heat; Radix Salviae Miltiorrhizae can coronary artery dilator, improve the heart and brain blood flow; Olibanum, Myrrha have the effect assistant of sedation and analgesia to reach extremity with Ramulus Cinnamomi; Semen Strychni has the merit that strengthens the blood circulation benefiting qi and nourishing blood; Fructus Lycii, Fructus Schisandrae Chinensis have the merit of the blood stasis dispelling of nourishing blood.The result of above-mentioned every medicine comprehensive function make Chinese medicine of the present invention have yang invigorating QI invigorating, promoting blood circulation and stopping pain, neck relax shoulder and, the effect of calming the mind and benefiting the brain.

The specific embodiment: get Radix Angelicae Sinensis 160g, Rhizoma Chuanxiong 120g, Radix Paeoniae Rubra 140g, Radix Rehmanniae 600g, Rhizoma Polygonati Odorati 140g, blue or green winter 200g, Fructus Lycii 200g, Rhizoma Cimicifugae 160g, Rhizoma Atractylodis 160g, Radix Codonopsis 210g, Radix Astragali 250g, Radix Puerariae 200g, Fructus Schisandrae Chinensis 140g, Ramulus Cinnamomi 140g, Radix Salviae Miltiorrhizae 140g, Olibanum (processed) 100g, Myrrha (processed) 100g, Semen Strychni (processed) 150g part.Its production method is: Olibanum, Myrrha are deoiled, and fried Semen Strychni yellowly grinds each flavor medicine together for smalls, sieves, mixes to spare and make honeyed pill.

Second kind of embodiment of the present invention: Radix Angelicae Sinensis 100g, Rhizoma Chuanxiong 80g, Radix Paeoniae Rubra 80g, Radix Rehmanniae 400g, Rhizoma Polygonati Odorati 100g, blue or green winter 100g, Fructus Lycii 100g, Rhizoma Cimicifugae 100g, Rhizoma Atractylodis 100g, Radix Codonopsis 150g, Radix Astragali 150g, Radix Puerariae 100g, Fructus Schisandrae Chinensis 100g, Ramulus Cinnamomi 100g, Radix Salviae Miltiorrhizae 100g, Olibanum (processed) 60g, Myrrha (processed) 60g, Semen Strychni (processed) 250g part.Its production method is: Olibanum, Myrrha are deoiled, and fried Semen Strychni yellowly grinds each flavor medicine together for smalls, sieves, mixes to spare and make honeyed pill.

The usage of this medicine and consumption: ante cibum warm boiled water, three times on the one, the each 10-15 of adult gram, children's reduces by half.

In order to estimate the clinical medicine safety of Chinese medicine of the present invention, it has been carried out toxicity test research, be reported as follows:

1. be subjected to test product: a kind of sick Chinese medicine of stiffness of the nape shoulder for the treatment of, every day 3 times, each 10-15 gram.

2. experimental animal: the white mice of Kunming kind, body weight 18-22 gram, male and female dual-purpose.

3. the preparation of dosage and test drug: get a kind of sick Chinese medicine of stiffness of the nape shoulder 45 grams for the treatment of, put and add the 100.0ml distilled water in the mortar and be uniformly dispersed, making concentration is 24% solution.Administering mode is a gastric infusion.

Three, the mensuration of median lethal dose(LD 50)

Get 9 of mices, divide three groups, but fail to find out the dosage of 100% animal dead.

Select 50 of the healthy mices of body weight 20 ± 2g for use, male and female half and half are divided into five groups at random, and are once oral

Gastric infusion, dosage are by geometric progression, and maximum dose level calculates with the maximum volume that can accept.Observed 7 days none death as a result after the administration.

Four, mtd test

Select 20 of healthy mices, male and female half and half, normally raise 1 after, administration is 3 times in 24 hours, 5 hours blanking times, total administration volume 120ml/kg observed 7 continuously, did not see untoward reaction and death condition, can think the oral avirulence of this medicine.

The maximum tolerated dose multiple is calculated as follows:

$=\frac{0.8\×3\×24\%}{20}\×\frac{60000}{6\×3\×0.4}$

Calculate if obey 45 grams every day by the adult, the result is 240 times of normal clinical dosage, illustrates that a kind of sick Chinese medicine of stiffness of the nape shoulder for the treatment of has safety.

A kind of sick Chinese medicine clinical summary of stiffness of the nape shoulder for the treatment of

One group to a kind of statistics for the treatment of in the sick Chinese medicine clinical observation material of stiffness of the nape shoulder.This organizes 5% case for observing the patient of treatment.Man's 100 examples wherein, woman's 41 examples, age 40-50 year 41 examples, 51-60 year 61 examples, 59 examples more than 61 years old, cervical spondylosis, hyperosteogeny, cervical vertebra are tetanic, cervical vertebra disfiguration, cervical spondylitis, 49 examples, scapulohumeral periarthritis, pain in my shoulder, swollen thick, the muscle atrophia of two arm pain fiber crops, finger, back side of head pain 36 examples, rheumatic scapulohumeral periarthritis, apathy, cervical-shoulder syndrome 33 examples, hyperosteogeny, lumbago, skelalgia, backache, traumatic injury 23 examples.Wherein Therapeutic Method is the patient to be divided into two groups at random, and 79 examples are organized in treatment, obeys capsule of the present invention, every day three times, and each 1 ball, 60 days is a course of treatment.Matched group 62 examples are taken other medicine, and 60 days is a course of treatment, withdraws other medicines before the administration, all do inspection before and after the treatment, and the result shows that the treatment group effective percentage of taking Chinese medicine of the present invention is 98% and matched group does not have obvious effects.

Claims (2)

1, a kind of sick Chinese medicine of stiffness of the nape shoulder for the treatment of is characterized in that this Chinese medicine made by the following weight proportion raw material: Radix Angelicae Sinensis 10-16 part, Rhizoma Chuanxiong 8-12 part, Radix Paeoniae Rubra 8-14 part, Radix Rehmanniae 40-60 part, Rhizoma Polygonati Odorati 10-14 part, blue or green winter 10-20 part, Fructus Lycii 10-20 part, Rhizoma Cimicifugae 10-16 part, Rhizoma Atractylodis 10-16 part, Radix Codonopsis 15-21 part, Radix Astragali 15-25 part, Radix Puerariae 10-20 part, Fructus Schisandrae Chinensis 10-14 part, Ramulus Cinnamomi 10-14 part, Radix Salviae Miltiorrhizae 10-14 part, Olibanum (processed) 6-10 part, Myrrha (processed) 6-10 part, Semen Strychni (processed) 15-25 part.

2, Chinese medicine as claimed in claim 1 is characterized in that production method is: Olibanum, Myrrha are deoiled, and fried Semen Strychni yellowly grinds each flavor medicine together for smalls, sieves, mixes to spare and make honeyed pill.