CN104666403A - Liniment for treating acariasis of domestic animal and preparation method thereof - Google Patents
Liniment for treating acariasis of domestic animal and preparation method thereof Download PDFInfo
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- CN104666403A CN104666403A CN201310642129.8A CN201310642129A CN104666403A CN 104666403 A CN104666403 A CN 104666403A CN 201310642129 A CN201310642129 A CN 201310642129A CN 104666403 A CN104666403 A CN 104666403A
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Abstract
The invention relates to liniment for treating acariasis of a domestic animal and a preparation method thereof. The liniment consists of the following components in parts by weight: 5-10 parts of sulfur, 1-5 parts of thunder god vine, 1-10 parts of camphor, 1-10 parts of calculus bovis, 1-10 parts of radix sophorae flavescentis and 10-80 part of waste engine oil. The liniment disclosed by the invention is prepared from traditional Chinese medicines and is combined with folk experiments, and the waste engine oil is taken as a carrier solvent to prepare the liniment. Pharmacodynamic tests prove that the liniment disclosed by the invention is rapid in insect expelling effect, good in insect killing effect and high in curative rate. Besides, the liniment disclosed by the invention is simple in preparation process and is liniment convenient to use, rapid in effect and used for treating the acariasis of the domestic animal.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of liniment for the treatment of acariasis of domestic animal and preparation method thereof.
Background technology
Mange and scab is the parasitogenic dermatitis due to scabies acarid.How occurring irregular pathological changes in domestic animal incidence, ill domestic animal play is itched, affected part of dawdling with strength, causes affected part depilation, exfoliation, pachyderma, follows the string.Squama, dirt, to be bonded together by hair and exudate, to form crust dirt.Whole body can be involved time serious.Scabies demodicid mite mainly contains 3 types, and because the life style of demodicid mite is different, recurrent position is also different.According to interrelated data, cause primary disease reason maximum be suck copperworm, be secondly food skin copperworm, minimum is perforation copperworm.Wherein eat skin copperworm once to see at the Niu Tizhong of north of China.
Suck copperworm (itch mite) to infect: this type main parasitic is at skin surface, and particularly ear, buttocks, abdominal part etc. are more serious.Its degree of itching is slightly poorer than perforation copperworm type, but then acutely itches when mouthpart thorn application on human skin draws lymph fluid, occurs the depilation speckle that boundary is obvious.Wherein have the pimple be dispersed in, the surrounding of speckle has transudate to ooze out, and the crust on depilation speckle is that yellowish-brown is attached on skin as shell.The degree that this type is itched, the color of crust and do not swell and can distinguish with other two types.
Food skin copperworm (sufficient demodicid mite) infects: this type considers skin to be worth doing to eat food and crust is made a living, and mainly encroach on root of the tail portion, anus, buttocks and the extremity of cattle, sometimes also betide back, breast abdomen and nares, this type is the one of itching the lightest in three types.But due to the excremental stimulation of a large amount of parasitic mite and allergy, when there is dermatitis and eczema sample symptom, then acutely itch.Its depilation degree is more more obvious than the former, has the feature of large area depilation.But all one's life no longer falls ill after most of sick cattle infected, general this kind of sick cattle often becomes the source of infection after curing.Time serious, skin oozes out transudate as allergy eczema, simultaneously with congested and hemorrhage, forms the bulk crust of picture be full of cracks sample, sometimes can involve whole body after treatment.
Perforation copperworm (acaricide) is infected: this type main parasitic in epidermis, and excavates worm road wherein, draws nutrition.Occur in head, cervical region at first, spread to shoulder, back and whole body gradually.This type is seldom shown in cattle, because demodicid mite excavates Liao Chong road at the epidermis of skin, so be the one of itching the most violent in 3 types, similar to the scabies of people.
At present, if the chemical medicine such as the drug main dichlorvos for the treatment of scabies or metrifonate, some drugs is banning drugs, therefore, explore effective safety low-poison medicine imperative, the present invention is basic with Chinese medicine, in conjunction with experience among the people, be made into liniment for the disease of clinical treatment scabies and selection scheme is provided.
Summary of the invention
The object of the present invention is to provide a kind of liniment for the treatment of acariasis of domestic animal, this liniment anthelminthic effect is fast, and good disinsection effect, cure rate is high.Processing technology of the present invention is simple, is the liniment that acariasis of domestic animal is treated in a kind of onset easy to use rapidly.
Another object of the present invention is to provide a kind of preparation method for the treatment of the liniment of acariasis of domestic animal.
The present invention is achieved by the following technical solutions:
Treat a liniment for acariasis of domestic animal, component and the ratio of weight and number thereof of its liniment are respectively:
Treat a preparation method for the liniment of acariasis of domestic animal, the step of its preparation method is as follows:
(1) take Radix Tripterygii Wilfordii, Calculus Bovis, Radix Sophorae Flavescentis respectively by weight ratio, knock down in weight abrading type super micron mill from dog-house, pulverize the Chinese medicine ultra-fine powder into diameter 10-20 micron;
(2) take sulfur by weight ratio, adding concentration is gradually 95% alcoholic solution, and limit edged stirs, until sulfur all dissolves, obtains solution A, for subsequent use;
(3) take Camphora by weight ratio, add 95% alcoholic solution gradually, limit edged stirs, until Camphora all dissolves, makes solution B, for subsequent use;
(4) take used oil by weight ratio to heat, the superfine powder adding step (1) and make is stirred after seething with excitement, carry out stirring 30-60min rapidly, when cooling to 40-50 DEG C, add the solution A of step (2) gained and the solution B of step (3) gained, after stirring, namely obtain the liniment finished product for the treatment of acariasis of domestic animal.
Advantage of the present invention and beneficial effect are:
1, the Chinese herb triperygium wilfordii that the liniment of this treatment acariasis of domestic animal adopts can dispel the wind, removing toxic substances, and parasite killing, also has the effect of antiinflammatory, bactericidal action and antipyretic effect etc. simultaneously in addition; Sulfur has parasite killing, kills demodicid mite and bactericidal action.It has selection toxicity to the fungal spore of Erysiphaceae, is therefore used as the protective fungicide of this section's disease for many years.Sulfur also has selection toxicity to demodicid mite class, so be also usually used in killing demodicid mite; Calculus Bovis has effect of heat-clearing and toxic substances removing, is conducive to the recovery of focus.Camphora has orifice opening, qi stagnation removing, wards off foul, killing parasites for relieving itching, reducing swelling and alleviating pain effect.Radix Sophorae Flavescentis function cures mainly as heat clearing and damp drying, parasite killing.These Chinese medicines can play synergism, play sufficient killing action to acaricide etc.
2, the used oil in the present invention early has application clinically among the people, although mechanism is not clear and definite, drug effect is verified.The present invention it can be used as pharmaceutical carrier, is also a kind of acting drug simultaneously, can plays the effect of more excellent treatment mange and scab.
3, superfine communication technique that the present invention adopts, improves Chinese medicine cell and breaks ratio, specific surface area, effective ingredient dissolution and bioavailability, and the strong drug effect facilitating Chinese medicine used plays.In addition, technique of the present invention is simple, be applicable to factorial praluction, and product is easy to use, has the advantage of cultivation clinical expansion.
Detailed description of the invention
The present invention is described in further detail by following examples.It should be noted that: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Sulfur involved in the present invention; Radix Tripterygii Wilfordii; Camphora; Calculus Bovis; Radix Sophorae Flavescentis; Used oil all commercially can be bought and obtain.
Embodiment 1
Treat a liniment for acariasis of domestic animal, component and the weight thereof of its liniment are respectively: sulfur 10g; Radix Tripterygii Wilfordii 5g; Camphora 10g; Calculus Bovis 10g; Radix Sophorae Flavescentis 20g; Used oil 80ml.
Treat a preparation method for the liniment of acariasis of domestic animal, the step of its preparation method is as follows:
(1) take Radix Tripterygii Wilfordii, Calculus Bovis, Radix Sophorae Flavescentis respectively by weight ratio, knock down in weight abrading type super micron mill from dog-house, pulverize the Chinese medicine ultra-fine powder into diameter 10-20 micron;
(2) take sulfur by weight ratio, adding concentration is gradually 95% alcoholic solution, and limit edged stirs, until sulfur all dissolves, obtains solution A, for subsequent use;
(3) take Camphora by weight ratio, add 95% alcoholic solution gradually, limit edged stirs, until Camphora all dissolves, makes solution B, for subsequent use;
(4) take used oil by weight ratio to heat, the superfine powder adding step (1) and make is stirred after seething with excitement, carry out stirring 30-60min rapidly, when cooling to 40-50 DEG C, add the solution A of step (2) gained and the solution B of step (3) gained, after stirring, namely obtain the liniment finished product for the treatment of acariasis of domestic animal.
Embodiment 2
Treat a liniment for acariasis of domestic animal, component and the weight thereof of its liniment are respectively: sulfur 5g; Radix Tripterygii Wilfordii 1g; Camphora 1g; Calculus Bovis 1g; Radix Sophorae Flavescentis 1g; Used oil 10ml.
The step of its preparation method is with embodiment 1.
Embodiment 3
Treat a liniment for acariasis of domestic animal, component and the weight thereof of its liniment are respectively: sulfur 7g; Radix Tripterygii Wilfordii 3g; Camphora 5g; Calculus Bovis 5g; Radix Sophorae Flavescentis 10g; Used oil 50ml.
The step of its preparation method is with embodiment 1.
Clinical practice is tested
1, experimental animal
Tianjin plant chooses the cattle farm of outburst cattle mange and scab, chooses morbidity cattle 10.Cardinal symptom is head, blister appears tuberosity, in eye limit, skin of neck, and spread to whole body subsequently, cattle body is become thin gradually.Niu Tiju itches, and sick cattle licks always and licks affected part, or dawdle in railing place around, causes skin injury and coat loss, and transudate is flowed out at tuberosity place, crust or be full of cracks etc. after dry.
2, laboratory diagnosis
The scurf of scraping affected part, put into plate and be placed in 40 DEG C of warm water and heat after 15min, microscopy under microscope, is diagnosed as sarcoptic mite.
3, test drug
The present invention, is produced by our company.
Metrifonate, purchases in Shandong Heng Jiayaohua company limited.
4, Therapeutic Method
10 sick cattle are divided into two groups at random, and one group is of the present invention group, and two groups is metrifonate group, often organizes 5 and suffers from cattle.Before test, first cut off cattle affected part and neighbouring by hair, then embrocate the present invention and 5% metrifonate solution respectively, once a day, until recovery from illness.Observe the clinical symptoms of disease.
5, result of the test
From clinical observation, after administration, two groups of scabies affected part symptoms are alleviated all to some extent, and the therapeutic effect of liniment group and metrifonate group is suitable, but treatment is after 1 week, and the drug effect of of the present invention group comparatively metrifonate group will be got well.Administration is after 2 weeks, and of the present invention group is healed substantially all, and metrifonate group is almost recovered at continuous treatment 3 each Zhou Houcai.Result of the test shows, anthelminthic effect of the present invention is fast, and good disinsection effect, cure rate is high.
Claims (2)
1. treat a liniment for acariasis of domestic animal, it is characterized in that: the component of this liniment and ratio of weight and number thereof are:
2. a preparation method for the liniment for the treatment of acariasis of domestic animal as claimed in claim 1, is characterized in that: the step of this preparation method is as follows:
(1) take Radix Tripterygii Wilfordii, Calculus Bovis, Radix Sophorae Flavescentis respectively by weight ratio, knock down in weight abrading type super micron mill from dog-house, pulverize the Chinese medicine ultra-fine powder into diameter 10-20 micron;
(2) take sulfur by weight ratio, adding concentration is gradually 95% alcoholic solution, and limit edged stirs, until sulfur all dissolves, obtains solution A, for subsequent use;
(3) take Camphora by weight ratio, add 95% alcoholic solution gradually, limit edged stirs, until Camphora all dissolves, makes solution B, for subsequent use;
(4) take used oil by weight ratio to heat, the superfine powder adding step (1) and make is stirred after seething with excitement, carry out stirring 30-60min rapidly, when cooling to 40-50 DEG C, add the solution A of step (2) gained and the solution B of step (3) gained, after stirring, namely obtain the liniment finished product for the treatment of acariasis of domestic animal.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111743916A (en) * | 2020-07-10 | 2020-10-09 | 广州迈高化学有限公司 | Pesticide for preventing and treating ectoparasites of livestock and poultry as well as preparation method and application thereof |
| CN114681539A (en) * | 2020-12-31 | 2022-07-01 | 鼎正新兴生物技术（天津）有限公司 | External lotion for treating scall mange and preparation method thereof |
Citations (1)
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| CN103285122A (en) * | 2013-06-13 | 2013-09-11 | 金品红 | Traditional Chinese medicine composition for treating swine mange and scab and preparation method thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103285122A (en) * | 2013-06-13 | 2013-09-11 | 金品红 | Traditional Chinese medicine composition for treating swine mange and scab and preparation method thereof |
Non-Patent Citations (5)
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| 《全国中兽医经验选编》编审组: "《全国中兽医经验选编》", 31 December 1977, 科学出版社 * |
| 冯洪钱编著: "《兽医本草拾遗》", 30 September 2002, 科学技术文献出版社 * |
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| 李术杭等: "家兔疥癣病，防治莫放松", 《江西农业科技》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111743916A (en) * | 2020-07-10 | 2020-10-09 | 广州迈高化学有限公司 | Pesticide for preventing and treating ectoparasites of livestock and poultry as well as preparation method and application thereof |
| CN114681539A (en) * | 2020-12-31 | 2022-07-01 | 鼎正新兴生物技术（天津）有限公司 | External lotion for treating scall mange and preparation method thereof |
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Application publication date: 20150603 |