CN114681539A - External lotion for treating scall mange and preparation method thereof - Google Patents
External lotion for treating scall mange and preparation method thereof Download PDFInfo
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- CN114681539A CN114681539A CN202011618353.XA CN202011618353A CN114681539A CN 114681539 A CN114681539 A CN 114681539A CN 202011618353 A CN202011618353 A CN 202011618353A CN 114681539 A CN114681539 A CN 114681539A
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- parts
- lotion
- sulfur
- decoction
- spina gleditsiae
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- 239000006210 lotion Substances 0.000 title claims abstract description 21
- 201000002266 mite infestation Diseases 0.000 title claims description 10
- 238000002360 preparation method Methods 0.000 title description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 18
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000000706 filtrate Substances 0.000 claims abstract description 16
- 239000011593 sulfur Substances 0.000 claims abstract description 16
- 229910052717 sulfur Inorganic materials 0.000 claims abstract description 16
- 206010063409 Acarodermatitis Diseases 0.000 claims abstract description 13
- 241000447727 Scabies Species 0.000 claims abstract description 13
- 208000005687 scabies Diseases 0.000 claims abstract description 13
- 238000001914 filtration Methods 0.000 claims abstract description 12
- 239000000047 product Substances 0.000 claims abstract description 8
- 238000005259 measurement Methods 0.000 claims abstract description 5
- 229940100617 topical lotion Drugs 0.000 claims abstract 2
- 241000830536 Tripterygium wilfordii Species 0.000 claims description 15
- 235000015398 thunder god vine Nutrition 0.000 claims description 15
- 241000319062 Lycoris radiata Species 0.000 claims description 10
- 241001633628 Lycoris Species 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 238000005406 washing Methods 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 230000001185 psoriatic effect Effects 0.000 claims 1
- 241000283073 Equus caballus Species 0.000 abstract description 6
- 208000003251 Pruritus Diseases 0.000 abstract description 6
- 230000007803 itching Effects 0.000 abstract description 5
- 206010039509 Scab Diseases 0.000 abstract description 3
- 208000027418 Wounds and injury Diseases 0.000 abstract description 3
- 230000006378 damage Effects 0.000 abstract description 3
- 208000014674 injury Diseases 0.000 abstract description 3
- 238000005057 refrigeration Methods 0.000 abstract description 2
- 241000283086 Equidae Species 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 244000045947 parasite Species 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 231100000167 toxic agent Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 241000238876 Acari Species 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 231100000360 alopecia Toxicity 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A topical lotion for the treatment of scabies comprises Sulfur, spina Gleditsiae, Bulbus Lycoridis Radiatae, and radix Tripterygii Wilfordii. In the invention, the components are weighed according to the measurement, water is added for decoction twice, the filtrate is mixed and filtered, the filtrate is concentrated, ethanol is added for standing, the ethanol is recovered after filtration, the concentration is carried out, the water is added for constant volume, and the finished product is obtained after refrigeration and filtration. When the lotion is used, the lotion is diluted with water according to the proportion of 1:10 and then washed twice a day for 5-8 days continuously, scabs and peels off at the skin burst position of a horse, the injury is reduced, and the itching feeling is weakened.
Description
Technical Field
The invention belongs to the technical field of prevention and treatment of equine parasitic diseases, and particularly relates to an external lotion for treating equine mange diseases and a preparation method thereof.
Background
The scabies of horses are chronic skin diseases caused by scabies parasitizing on the skin of horses. Clinically characterized by severe itching, eczematous dermatitis, alopecia and high infectivity. Scabies are widely distributed around the world and often parasitize the soft and hairy parts of horse skin, which can hinder the growth and development of colts and young horses and reduce the milk yield of lactating horses. The main infectious sources of the disease are sick horses and animals with mites, the main transmission route is contact infection, and horses of various ages can be infected, but the susceptibility of foals is the highest.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the external lotion for treating the mange scabies, which has scientific proportion, good treatment effect and no toxic or side effect.
The invention adopts the technical scheme that the external lotion for treating the mange diseases is characterized in that: the composition comprises the following components in parts by weight:
15-20 parts of sulfur;
15-20 parts of spina gleditsiae;
11-15 parts of lycoris radiate;
5-10 parts of tripterygium wilfordii.
The invention also aims to provide a preparation method of the external lotion for treating the mange diseases, which is characterized by comprising the following steps: the method comprises the following steps:
weighing sulfur, spina gleditsiae, lycoris radiata and tripterygium wilfordii according to measurement, adding into 10 times of clear water by weight, decocting twice for 2 hours each time,
filtering after the first decoction, wherein filtrate is reserved, and adding 10 times of clear water by weight into the medicine dregs for the second decoction and filtering, and reserving the filtrate;
thirdly, combining the filtrates obtained in the two steps, concentrating the filtered filtrate to be proper, adding 75% ethanol, uniformly stirring, and standing for 24 hours;
fourthly, filtering the product obtained in the step three, recovering ethanol, concentrating to a proper amount, adding water to a constant volume, refrigerating for 24 hours, and filtering to obtain a finished product.
The invention also provides a use method of the external lotion for treating the mange diseases, which is characterized by comprising the following steps: the medicament of claim 1 or 2 is used for washing affected parts of the sick horses, and the washing liquid is diluted with water according to the ratio of 1:10 and then washed twice a day for 5-8 days continuously.
The invention has the advantages and positive effects that:
in the invention, sulfur, spina gleditsiae, lycoris radiata and tripterygium wilfordii are weighed according to the measurement, water is added for decoction twice, the filtrates are mixed and filtered, the filtrate is concentrated, ethanol is added for standing, the ethanol is recovered after filtration, the concentration is carried out, the water is added for constant volume, and the finished product is obtained after refrigeration and filtration. When the lotion is used, the lotion is diluted with water according to the proportion of 1:10 and then washed twice a day for 5-8 days continuously, scabs and peels off at the skin burst position of a horse, the injury is reduced, and the itching feeling is weakened.
Detailed Description
The present invention is further illustrated by the following examples, which are intended to be illustrative, not limiting and are not intended to limit the scope of the invention.
The invention discloses an external lotion for treating mange diseases, which is characterized in that: the composition comprises the following components in parts by weight:
15-20 parts of sulfur;
15-20 parts of spina gleditsiae;
11-15 parts of lycoris radiate;
5-10 parts of tripterygium wilfordii.
More preferred embodiments are: the composition comprises the following components in parts by weight:
20 parts of sulfur;
20 parts of spina gleditsiae;
15 parts of lycoris radiate;
and 5 parts of tripterygium wilfordii.
The medicine of the invention comprises: sulfur is a mineral substance, is acidic, warm and toxic, and enters kidney and large intestine channels, has effects of killing parasite and relieving itching for external use, and can be used for treating scabies, eczema and skin pruritus; spina Gleditsiae has effects of relieving swelling, removing toxic substance, expelling pus, and killing parasite; the lycoris has the effects of detoxifying, resolving masses, relieving swelling and killing insects; tripterygium wilfordii hook F.H. has effects of dispelling pathogenic wind, removing dampness, promoting blood circulation, dredging collaterals, relieving swelling and pain, killing parasite, relieving inflammation, and removing toxic substance.
Example 1
A lotion for external use for treating scabies and a preparation method thereof, which comprises the following components:
20 parts of sulfur, 20 parts of spina gleditsiae, 15 parts of lycoris radiata and 5 parts of tripterygium wilfordii
Weighing sulfur, spina gleditsiae, lycoris radiata and tripterygium wilfordii according to measurement, and adding the weighed sulfur, spina gleditsiae, lycoris radiata and tripterygium wilfordii into clear water with the weight being 10 times that of the weighed materials to decoct for two times;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, the decoction dregs are added with clear water with the weight being 10 times of that of the decoction dregs for the second decoction, the time is 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates obtained in the two steps, concentrating the filtered filtrate to a proper amount, adding ethanol to enable the ethanol content to be 75%, uniformly stirring, and standing for 24 hours;
fourthly, filtering the product obtained in the step three, recovering ethanol, concentrating to a proper amount, adding water to a constant volume, refrigerating for 24 hours, and filtering to obtain a finished product.
Example 2
A lotion for external use for treating mange scabies and a preparation method thereof are composed of the following components:
15 parts of sulfur, 20 parts of spina gleditsiae, 10 parts of lycoris radiata and 5 parts of tripterygium wilfordii
The preparation method of the traditional Chinese medicine compound preparation is carried out according to the embodiment 1.
Example 3
A lotion for external use for treating scabies and a preparation method thereof, which comprises the following components:
20 parts of sulfur, 15 parts of spina gleditsiae, 10 parts of lycoris radiata and 5 parts of tripterygium wilfordii
The preparation method of the traditional Chinese medicine compound preparation is carried out according to the embodiment 1.
The medicament of claims 1 and 2 is fed to 4 horses diagnosed with scabies in Tianjin Xiqing. When the lotion is used, the lotion is diluted with water according to the proportion of 1:10 and then washed twice a day for 5-8 days continuously, scabbing and falling off at the skin burst position of a horse, the injury is reduced, and the itching feeling is weakened.
Claims (4)
1. A lotion for external use for treating scabies is characterized in that: the composition comprises the following components in parts by weight:
15-20 parts of sulfur;
15-20 parts of spina gleditsiae;
11-15 parts of lycoris radiata;
5-10 parts of tripterygium wilfordii.
2. The external lotion for treating scabies according to claim 1, wherein said lotion comprises: the composition comprises the following components in parts by weight:
20 parts of sulfur;
20 parts of spina gleditsiae;
15 parts of lycoris radiate;
and 5 parts of tripterygium wilfordii.
3. A topical lotion for the treatment of psoriatic mange, according to claim 1 or 2, characterized in that: the method comprises the following steps:
weighing sulfur, spina gleditsiae, lycoris radiata and tripterygium wilfordii according to measurement, and adding the weighed sulfur, spina gleditsiae, lycoris radiata and tripterygium wilfordii into clear water with the weight being 10 times that of the weighed materials to decoct for two times;
secondly, after the first decoction is carried out for 2 hours, filtrate is reserved, and the dregs of a decoction are added with clear water with the weight of 10 times of that of the dregs of a decoction for the second decoction for 1.5 hours, and the filtrate is reserved;
thirdly, combining the filtrates obtained in the two steps, concentrating the filtered filtrate to a proper amount, adding ethanol to enable the ethanol content to be 75%, uniformly stirring, and standing for 24 hours;
fourthly, filtering the product obtained in the step three, recovering ethanol, concentrating to a proper amount, adding water to a constant volume, refrigerating for 24 hours, and filtering to obtain a finished product.
4. A lotion for external use for treating scabies is characterized in that: the use of the pharmaceutical preparation according to claim 1 or 2, wherein the washing solution is diluted with water at a ratio of 1:10 and washed twice a day for 5 to 8 consecutive days.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011618353.XA CN114681539A (en) | 2020-12-31 | 2020-12-31 | External lotion for treating scall mange and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011618353.XA CN114681539A (en) | 2020-12-31 | 2020-12-31 | External lotion for treating scall mange and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114681539A true CN114681539A (en) | 2022-07-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011618353.XA Pending CN114681539A (en) | 2020-12-31 | 2020-12-31 | External lotion for treating scall mange and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114681539A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104666403A (en) * | 2013-12-03 | 2015-06-03 | 天津市中敖饲料有限公司 | Liniment for treating acariasis of domestic animal and preparation method thereof |
| CN105963442A (en) * | 2016-07-03 | 2016-09-28 | 张俊清 | Mongolian medicine composition for treating sheep scab disease |
| CN109464512A (en) * | 2018-12-28 | 2019-03-15 | 鼎正动物药业（天津）有限公司 | It is a kind of for treating the external wash liquid and preparation method thereof of pig scabies |
-
2020
- 2020-12-31 CN CN202011618353.XA patent/CN114681539A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104666403A (en) * | 2013-12-03 | 2015-06-03 | 天津市中敖饲料有限公司 | Liniment for treating acariasis of domestic animal and preparation method thereof |
| CN105963442A (en) * | 2016-07-03 | 2016-09-28 | 张俊清 | Mongolian medicine composition for treating sheep scab disease |
| CN109464512A (en) * | 2018-12-28 | 2019-03-15 | 鼎正动物药业（天津）有限公司 | It is a kind of for treating the external wash liquid and preparation method thereof of pig scabies |
Non-Patent Citations (2)
| Title |
|---|
| 秦波等: "牛三种体外寄生虫病的诊治", 《现代畜牧科技》 * |
| 薛志成: "疥癣病治疗十法", 《辽宁畜牧兽医》 * |
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Application publication date: 20220701 |