CN104623551A - Traditional Chinese medicine throat lozenge for refreshing breath - Google Patents

Abstract

The invention discloses a traditional Chinese medicine throat lozenge for refreshing breath and relates to the technical field of throat lozenges. The traditional Chinese medicine throat lozenge is composed of the following components in percentage by weight: 0.5-2% of fennel extract, 0.5-2% of curcuma aromatica extract, 0.5-2% of coptis extract, 0.5-2% of green tea extract, 5-7% of Arabic gum, 68-72% of liquid glucose, 0.1-0.2% of menthol, 0.8-1.0% of extractum glycyrrhizae and the balance of distilled water. Compared with the prior art, the traditional Chinese medicine throat lozenge has the advantage that the bacteriostatic ability of the coptis extract and the green tea extract and the fragrance of the fennel extract and the curcuma aromatica extract are used for improving the oral cavity smell together, in order to prolong fresh air in oral cavities.

Description

Breath freshening Chinese medicine throat lozenge

Technical field

The present invention relates to throat lozenge technical field, especially breath freshening throat lozenge.

Background technology

Dental care product is clean and health product indispensable in people's daily life, and this series products is of a great variety, is mainly used in keeping oral cavity and cleaning of teeth, promotion breath freshening, nurses gingiva, safeguards oral cavity good environment etc.; Oral cavity cleaning and nursing product are indispensable cavity sanitary products in people's daily life; In recent years, because consumer healthcare realizes continuous enhancing, more requirement is proposed to dental care products, also to increase some auxiliary prevention oral diseases except cleaning one's teeth, oral cavity being had to the function of nursing health effect, therefore there is in dental care products both domestic and external various functional product and become the market mainstream, again due to the advantage that Chinese medicinal plant active component has the Western medicine such as natural, safe incomparable, therefore with the functional emphasis becoming Developing of active ingredient of Chinese herbs on market.

Breath freshening is the basic expressions that oral cavity does not have abnormal flavour, and halitosis certainly will produce halitosis.The Main Ingredients and Appearance of halitosis abnormal smells from the patient is volatile sulfur compounds (volatilesulfur compounds, VSCs), and wherein 90% is hydrogen sulfide (H2S) and methanthiol (CH3SH).Large quantity research proves, oral microorganism and halitosis and implication medium sulphide content in close relations, wherein spirillum is one of oral microorganism relevant with the generation of volatilize in oral cavity sulfur compound and halitosis.Therefore, breath freshening be made, must halitosis be removed.

Throat lozenge is a kind of common oral cavity cleaning and nursing product, a lot of people has the custom wet one's whistle containing throat lozenge, throat lozenge is contained in the secretion that can increase saliva in oral cavity, the saliva of dissolving throat lozenge will infiltrate gingiva, if the Chinese medicine with breath freshening can be combined with it, can medication prevention not need deliberately again.

Summary of the invention

The problem that the present invention solves is to provide a kind of throat lozenge, and this throat lozenge has the effect that effectively can extend the oral cavity halitosis pure and fresh time.

In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is: the percentage by weight of its component is as follows:

Fructus Foeniculi extract 0.5%-2%; Radix Curcumae extract 0.5-2%; Rhizoma Coptidis extract 0.5-2%; Green tea extract 0.5-2%; Arabic gum 5%-7%; Liquid glucose 68%-72%; Mentholum 0.1%-0.2%; Radix Glycyrrhizae extractum 0.8%-1.0%; Distilled water surplus.

The said Fructus Foeniculi of the present invention is the dry mature fruit of Umbelliferae herbaceos perennial Fructus Foeniculi.Gas is aromatic, and taste is sweet, Xin Wen, and dispersing cold for relieving pain can control hernia stomachache, testis swelling and hanging down of either of the testes distending pain, dysmenorrhea.

Radix Curcumae of the present invention is the tuber of Zingiberaceae herbaceos perennial Rhizoma Curcumae Longae, RADIX CURCUMAE, Rhizoma Curcumae etc.Feeble QI is fragrant, has Rhizoma Zingiberis Recens taste.Arduous cold, blood-activating and qi-promoting pain relieving, dispersing the stagnated live-QI to relieve the stagnation of QI, breast, the side of body, the stomachache for the treatment of qi depression to blood stasis.Especially women's abdominal pain during menstruation, mammary swelling etc.Clear dampness-heat in the liver and gallbladder, and can cholagogic and lithagogue, for cholelithiasis.Can also control early rich by turmeric powder.

Rhizoma Coptidis of the present invention, another name Wang Lian, Zhi Lian are the rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao, coptis omeiensis or Coptis teeta; Rhizoma Coptidis is used as medicine with rhizome, has inhibitory action to various pathogenic bacteria.

Green tea extract of the present invention is the active component extracted from green tea blade, mainly comprises tea polyphenols (catechin) etc.; There is the effect such as antioxidation, scavenging free radicals.

Use with the form of Fructus Foeniculi extract, Radix Curcumae extract, Rhizoma Coptidis extract and green tea extract in the present invention, the extracting method of Fructus Foeniculi extract of the present invention, Radix Curcumae extract, Rhizoma Coptidis extract and green tea extract is that the medicinal effects of every taste Chinese medicine is broken into fine powder, cross 150 mesh sieves, 3 hours are extracted with the alcohol heating reflux of 10 times amount, extract 3 times, then extracting solution concentrating under reduced pressure become extractum or be dried to powdery; Extracting method is not limited to said method, and the additive method such as supercritical extraction, ultrasonic extraction also can be adopted to extract.

Prove through overtesting, add using Fructus Foeniculi extract, Radix Curcumae extract, Rhizoma Coptidis extract and green tea extract as active ingredient of Chinese herbs in this throat lozenge, utilize the bacteriostasis of Rhizoma Coptidis extract and green tea extract and Fructus Foeniculi extract, the fragrance of Radix Curcumae extract improves oral cavity gas jointly, intraoral fresh air is extended.

Detailed description of the invention

Below in conjunction with embodiment, the present invention will be further described.In following each embodiment, involved percentage ratio except as otherwise noted, is all calculate by weight percentage.

The throat lozenge constitutive material of embodiment 1-5 and weight percent content are as following table:

clinical trial part:

1, sulfide analyzer analytic process

Use portable sulfide analyzer (Halimeter 4710-3 type, American I nterscan company manufactures), directly read the ppb concentration value of experimenter's implication medium sulphide content (volatile sulfur comounds, VSCs), record implication value.

Method requires: before test, first by instrument adjustment 0, advises tester to remain silent 2min.Be connected with analyzer plastic suction pipe one end during test, the other end inserts 3cm in experimenter's mouth, can not contact with back, lip.Advise experimenter's nasal respiration, when peak value appears in instrument, take out suction pipe, record peak value.Again measure after numerical value back to zero, repeat 3 times, get its meansigma methods.

2, samples selection:

Be greater than 150 ppb persons for entry standard with VSCs, and experimenter can not have digestive system, respiratory system, whole body system disease, suffer from extensive dental caries and periodontal disease, experimental session can not use non-hormone anti-inflammatory agent or antibiotic person in continuous more than 3 days.

3, material:

Consumer uses embodiment 2,4,5 throat lozenge and blank throat lozenge respectively.A throat lozenge is embodiment 2, B throat lozenge be embodiment 4, C throat lozenge be embodiment 5, D throat lozenge is not containing the blank sample of fresh breath composition.

4, test operation

At the trial, 160 people of inclusive criteria are divided into 4 groups at random, often organize 40 people.Provide different throat lozenges to each experimenter by group, each containing 8 minutes, got back to after 1 hour, 12 hours and check that place is rechecked.After this, experimental subject, by throat lozenge, each 3 minutes, can not use other oral health care products in the meantime or take antiinflammatory medicine, uses 1 week and 2 Zhou Houzai recheck.The results are shown in following table:

Experiment before and after with Halimiter detect implication value ( ± s, ppb)

Interpretation of result: can see from upper table, each group implication value there was no significant difference before and after experiment, illustrative experiment baseline has comparability.Use after throat lozenge wets one's whistle, the implication value often organized has certain decline, also can keep the pure and fresh of implication to a certain extent, but use the pure and fresh composition throat lozenge contained by this experiment then can improve the degree of breath freshening even if illustrate with common throat lozenge.After brushing teeth 12 hours, use No. A, No. B, C throat lozenge be better than using the fresh breath effects of control sample, illustrates use this experiment contain effect that deodorization composition throat lozenge has the prolongation breath freshening time; After wetting one's whistle 1 week, two weeks, use No. A, No. B, C throat lozenge has good antihalitosis effect.

Claims (1)

1. a breath freshening throat lozenge, is characterized in that being made up of the component of following percentage by weight:

Fructus Foeniculi extract 0.5%-2%; Radix Curcumae extract 0.5-2%; Rhizoma Coptidis extract 0.5-2%; Green tea extract 0.5-2%; Arabic gum 5%-7%; Liquid glucose 68%-72%; Mentholum 0.1%-0.2%; Radix Glycyrrhizae extractum 0.8%-1.0%; Distilled water surplus.