CN104606383A - Traditional Chinese medicine composition for treating osteoarthritis - Google Patents
Traditional Chinese medicine composition for treating osteoarthritis Download PDFInfo
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- CN104606383A CN104606383A CN201510034920.XA CN201510034920A CN104606383A CN 104606383 A CN104606383 A CN 104606383A CN 201510034920 A CN201510034920 A CN 201510034920A CN 104606383 A CN104606383 A CN 104606383A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating osteoarthritis. The traditional Chinese medicine composition is prepared from the following raw medicines in parts by weight: 5 to 25 parts of astragalus membranaceus, 5 to 20 parts of geranium wilfordii, 10 to 40 parts of saussurea involucrate, 10 to 40 parts of herba epimedii, 5 to 25 parts of callicarpa bodeinieri, 5 to 20 parts of herba pyrolae, 5 to 20 parts of oenothera biennis, 10 to 30 parts of schizophragma integrifolium, 5 to 20 parts of coriolus versicolor, 10 to 40 parts of radix rehmanniae preparata, 5 to 20 parts of radix polygonum multiflorum preparata, 10 to 30 parts of rhizoma cibotii, 10 to 40 parts of radix angelicae, 5 to 25 parts of ardisia japonica, 5 to 20 parts of China rose, 5 to 25 parts of paeonia veitchii, 10 to 30 parts of pawpaw, 10 to 30 parts of radix paeoniae alba, 5 to 20 parts of berba aristolochiae mollissimae, 5 to 25 parts of pine nodular branch, 5 to 20 parts of kadsura pepper stem, 10 to 30 parts of ligusticum wallichii, and 6 parts of radix liquiritiae. The traditional Chinese medicine composition has the effects of nourishing liver and kidney, relaxing tendons and activating collaterals, eliminating cold to stop pain, dispelling wind and eliminating dampness, promoting blood circulation to remove blood stasis, and has an obvious effect on treating osteoarthritis, and the effect is reliable.
Description
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of osteoarthritis.
Background technology
Osteoarthritis, also known as degenerative osteoarthritis, is a kind of chronic joint disease being feature with the degeneration of articular cartilage, destruction and hyperosteogeny, is mainly in middle-aged and elderly people.Osteoarthritis main manifestations is that arthralgia and activity are dumb, and x-ray performance joint space narrows, and subchondral bone matter is fine and close, and bone trabecula ruptures, and have sclerosis and cystis degeneration, joint margins has lip sample hypertrophy, and later stage epiphysis distortion, articular surface is uneven.At present, western medical treatment comprises operative treatment, non-operative treatment and naturopathy.Operative treatment is greatly traumatic, and easily occurs infecting, blood vessel, nerve injury, skin, osteonecrosis, the bad complication such as joint motion is limited, and curative effect is also unstable; What non-operative treatment was the most frequently used is exactly take analgesic and antibiotic medicine, but this method cannot solve the basic Autoimmune Disorders pathomechanism of osteoarthritis, and this type of medicine of long-term taking can cause addiction to rely on and gastrointestinal destroys; Though naturopathy has certain effect, the course for the treatment of is long, and curative effect is not consolidated.
Motherland's medical science thinks that osteoarthritis belongs to Chinese medicine " rheumatism involving the bone ", " knee joint numbness " category.Many by caused by liver and kidney deficiency, the evil invasion muscles and bones of wind and cold wet three, phlegm-damp blood stasis knot is with caused by joint.
According to theory of Chinese medical science, for the pathogeny of osteoarthritis, adopt the method for the treatment of of nourishing the liver and kidney, relaxing muscles and tendons and activating QI and blood in the collateral, dispersing cold for relieving pain, expelling wind and removing dampness, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome traumatic large, non-operative treatment side effect large, naturopathy curative effect the is undesirable deficiency of operative treatment in prior art, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of osteoarthritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Astragali 5-25 part, Herba Erodii 5-20 part, Herba Saussureae Involueratae 10-40 part, Herba Epimedii 10-40 part, Radix Callicarpae Bodinieri 5-25 part, Herba Pyrolae 5-20 part, Radix Oenotherae erythrosepalae 5-20 part, Cortex schizophragmatis integrifolii radicis 10-30 part, Coriolous Dersicolor (Fr.) Quel 5-20 part, Radix Rehmanniae Preparata 10-40 part, Radix Polygoni Multiflori Preparata 5-20 part, Rhizoma Cibotii 10-30 part, Radix Angelicae Dahuricae 10-40 part, Herba Ardisiae Japonicae 5-25 part, Flos Rosae Chinensis 5-20 part, grass Paeonia suffruticosa 5-25 part, Fructus Chaenomelis 10-30 part, Radix Paeoniae Alba 10-30 part, Herba Aristolochiae Mollissimae 5-20 part, Lignum Pini Nodi 5-25 part, Caulis Piperis Kadsurae 5-20 part, Rhizoma Chuanxiong 10-30 part, 6 parts, Radix Glycyrrhizae.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight are: the Radix Astragali 15 parts, Herba Erodii 10 parts, Herba Saussureae Involueratae 30 parts, Herba Epimedii 30 parts, Radix Callicarpae Bodinieri 15 parts, Herba Pyrolae 10 parts, Radix Oenotherae erythrosepalae 10 parts, Cortex schizophragmatis integrifolii radicis 20 parts, Coriolous Dersicolor (Fr.) Quel 10 parts, 30 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata 10 parts, Rhizoma Cibotii 20 parts, the Radix Angelicae Dahuricae 30 parts, Herba Ardisiae Japonicae 15 parts, Flos Rosae Chinensis 10 parts, grass 15 parts, Paeonia suffruticosa, Fructus Chaenomelis 20 parts, the Radix Paeoniae Alba 20 parts, Herba Aristolochiae Mollissimae 10 parts, Lignum Pini Nodi 15 parts, Caulis Piperis Kadsurae 10 parts, Rhizoma Chuanxiong 20 parts, 6 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Astragali has effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema; Herba Erodii has effect of wind-damp dispelling, the meridian dredging, antidiarrheal dysentery; Herba Saussureae Involueratae has kidney invigorating and YANG supporting, effect of regulating menstruation, hemostasis; Herba Epimedii has effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Radix Callicarpae Bodinieri has effect of dissipating blood stasis hemostasis, expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling; Herba Pyrolae has the kidney invigorating bone strengthening
,expelling wind and removing dampness
,cough-relieving
,effect of hemostasis; Radix Oenotherae erythrosepalae has effect of bone and muscle strengthening, expelling wind and removing dampness; Cortex schizophragmatis integrifolii radicis has effect of relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and activating blood circulation; Coriolous Dersicolor (Fr.) Quel has invigorating spleen to remove dampness, relieving cough and asthma, heat-clearing and toxic substances removing, antineoplastic effect; Radix Rehmanniae Preparata has effect of yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Radix Polygoni Multiflori Preparata has effect of invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening; Rhizoma Cibotii has the effect in invigorating the liver and kidney, strong spinal column, wind-damp dispelling, sharp joint; The Radix Angelicae Dahuricae has effect of the cold expelling that induces sweat, expelling pathogenic wind and restoring the functions of orifices in face, promoting blood circulation and stopping pain, dampness leukorrhagia stopping, detumescence row; Herba Ardisiae Japonicae has relieving cough and resolving phlegm, effect of removing toxic substances, promoting blood circulation and stopping pain of dispeling the wind; Flos Rosae Chinensis has effect of promoting blood flow to regulate menstruation, removing toxic substances and promoting subsidence of swelling; Grass Paeonia suffruticosa has effect of heat-clearing and toxic substances removing, expelling wind and removing dampness; Fructus Chaenomelis has effect of removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Herba Aristolochiae Mollissimae has expelling wind and removing dampness
,promoting blood circulation to remove obstruction in the collateral
,effect of pain relieving; Lignum Pini Nodi has dispeiling pathogenic wind and removing dampness
,channels sootheing and network vessel quickening
,effect of promoting blood circulation and stopping pain; Caulis Piperis Kadsurae has effect of wind-damp dispelling, the meridian dredging, stopping numbness pain; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, plays effect of nourishing the liver and kidney, relaxing muscles and tendons and activating QI and blood in the collateral, dispersing cold for relieving pain, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling altogether, reach treating both the principal and secondary aspects of a disease to the treatment of osteoarthritis.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 93%, cure rate 69%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 15g, Herba Erodii 10g, Herba Saussureae Involueratae 30g, Herba Epimedii 30g, Radix Callicarpae Bodinieri 15g, Herba Pyrolae 10g, Radix Oenotherae erythrosepalae 10g, Cortex schizophragmatis integrifolii radicis 20g, Coriolous Dersicolor (Fr.) Quel 10g, Radix Rehmanniae Preparata 30g, Radix Polygoni Multiflori Preparata 10g, Rhizoma Cibotii 20g, Radix Angelicae Dahuricae 30g, Herba Ardisiae Japonicae 15g, Flos Rosae Chinensis 10g, careless Paeonia suffruticosa 15g, Fructus Chaenomelis 20g, Radix Paeoniae Alba 20g, Herba Aristolochiae Mollissimae 10g, Lignum Pini Nodi 15g, Caulis Piperis Kadsurae 10g, Rhizoma Chuanxiong 20g, Radix Glycyrrhizae 6g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 10g, Herba Erodii 20g, Herba Saussureae Involueratae 15g, Herba Epimedii 40g, Radix Callicarpae Bodinieri 5g, Herba Pyrolae 20g, Radix Oenotherae erythrosepalae 12g, Cortex schizophragmatis integrifolii radicis 25g, Coriolous Dersicolor (Fr.) Quel 5g, Radix Rehmanniae Preparata 40g, Radix Polygoni Multiflori Preparata 15g, Rhizoma Cibotii 25g, Radix Angelicae Dahuricae 10g, Herba Ardisiae Japonicae 20g, Flos Rosae Chinensis 5g, careless Paeonia suffruticosa 25g, Fructus Chaenomelis 15g, Radix Paeoniae Alba 30g, Herba Aristolochiae Mollissimae 12g, Lignum Pini Nodi 20g, Caulis Piperis Kadsurae 12g, Rhizoma Chuanxiong 30g, Radix Glycyrrhizae 12g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 20g, Herba Erodii 5g, Herba Saussureae Involueratae 25g, Herba Epimedii 10g, Radix Callicarpae Bodinieri 20g, Herba Pyrolae 5g, Radix Oenotherae erythrosepalae 15g, Cortex schizophragmatis integrifolii radicis 10g, Coriolous Dersicolor (Fr.) Quel 20g, Radix Rehmanniae Preparata 15g, Radix Polygoni Multiflori Preparata 12g, Rhizoma Cibotii 30g, Radix Angelicae Dahuricae 15g, Herba Ardisiae Japonicae 25g, Flos Rosae Chinensis 12g, careless Paeonia suffruticosa 20g, Fructus Chaenomelis 10g, Radix Paeoniae Alba 25g, Herba Aristolochiae Mollissimae 5g, Lignum Pini Nodi 25g, Caulis Piperis Kadsurae 5g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 10g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 5g, Herba Erodii 15g, Herba Saussureae Involueratae 10g, Herba Epimedii 25g, Radix Callicarpae Bodinieri 10g, Herba Pyrolae 15g, Radix Oenotherae erythrosepalae 5g, Cortex schizophragmatis integrifolii radicis 30g, Coriolous Dersicolor (Fr.) Quel 15g, Radix Rehmanniae Preparata 10g, Radix Polygoni Multiflori Preparata 20g, Rhizoma Cibotii 10g, Radix Angelicae Dahuricae 25g, Herba Ardisiae Japonicae 10g, Flos Rosae Chinensis 20g, careless Paeonia suffruticosa 5g, Fructus Chaenomelis 25g, Radix Paeoniae Alba 10g, Herba Aristolochiae Mollissimae 15g, Lignum Pini Nodi 5g, Caulis Piperis Kadsurae 20g, Rhizoma Chuanxiong 10g, Radix Glycyrrhizae 8g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 25g, Herba Erodii 12g, Herba Saussureae Involueratae 40g, Herba Epimedii 10g, Radix Callicarpae Bodinieri 25g, Herba Pyrolae 12g, Radix Oenotherae erythrosepalae 20g, Cortex schizophragmatis integrifolii radicis 15g, Coriolous Dersicolor (Fr.) Quel 12g, Radix Rehmanniae Preparata 25g, Radix Polygoni Multiflori Preparata 5g, Rhizoma Cibotii 15g, Radix Angelicae Dahuricae 40g, Herba Ardisiae Japonicae 5g, Flos Rosae Chinensis 15g, careless Paeonia suffruticosa 10g, Fructus Chaenomelis 30g, Radix Paeoniae Alba 15g, Herba Aristolochiae Mollissimae 20g, Lignum Pini Nodi 10g, Caulis Piperis Kadsurae 15g, Rhizoma Chuanxiong 25g, Radix Glycyrrhizae 5g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of osteoarthritis given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, man 46 example, female 54 example, 35 ~ 75 years old age.
Two, diagnosis basis: with reference to State Administration of Traditional Chinese Medicine's " Chinese medical disease Standardization of diagnosis and curative effect " osteoarthritis diagnostic criteria of formulating in 1994:
1, middle-aged and elderly people mostly is;
2, the periarticular pain of recurrent exerbation, joint bear a heavy burden time pain increase the weight of, time have swelling;
There is coarse joint crepitus when 3, bending and stretching joint more;
4, x-ray shows joint margins hyperosteogeny, and joint space obviously narrows;
5, rheumatoid arthritis except.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Four, criterion of therapeutical effect: with reference to State Administration of Traditional Chinese Medicine's " Chinese medical disease Standardization of diagnosis and curative effect " osteoarthritis efficacy assessment standard of formulating in 1994:
(1), cure: pain disappears, joint movement function recovers normal;
(2), effective: pain obviously alleviates, and joint movement function improves;
(3), effective: pain alleviates to some extent, and joint motion makes moderate progress;
(4), invalid: arthralgia and range of activity are without improvement.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-10 the course for the treatment of, and recovery from illness 69 example, follows up a case by regular visits to and have no recurrence; Effective 15 examples, effective 9 examples, invalid 7 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1:
Cui, man, 39 years old.Occurred double knee joint pain before 2 years, time heavy burden in joint, pain increases the weight of, time have swelling, limitation of activity, once oral western medicine treatment, but poor effect.Double knee joint pain increases the weight of in this year, and the regression of film making display double knee joint, joint space is asymmetric, is diagnosed as: two knee osteoarthritis.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, conscious double knee joint pain comparatively before obviously alleviate; Continue to take 2 courses for the treatment of, pain disappears, and joint movement function recovers normal.
Case 2:
Korea Spro, female, 52 years old.Two knee joint swelling, weak, pain, squat down limited.Later stage occur double knee joint swelling, pain symptom aggravation.Be diagnosed as: two knee osteoarthritis.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, double knee joint pain, swelling alleviate greatly, and function of squatting down obviously is improved; Continue to take 2 courses for the treatment of, two knee joint swelling, weak, pain disappear, squat down and other movable functions recover normal.Follow up a case by regular visits to and do not recur half a year.
Claims (2)
1. treat the Chinese medicine composition of osteoarthritis for one kind, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Astragali 5-25 part, Herba Erodii 5-20 part, Herba Saussureae Involueratae 10-40 part, Herba Epimedii 10-40 part, Radix Callicarpae Bodinieri 5-25 part, Herba Pyrolae 5-20 part, Radix Oenotherae erythrosepalae 5-20 part, Cortex schizophragmatis integrifolii radicis 10-30 part, Coriolous Dersicolor (Fr.) Quel 5-20 part, Radix Rehmanniae Preparata 10-40 part, Radix Polygoni Multiflori Preparata 5-20 part, Rhizoma Cibotii 10-30 part, Radix Angelicae Dahuricae 10-40 part, Herba Ardisiae Japonicae 5-25 part, Flos Rosae Chinensis 5-20 part, grass Paeonia suffruticosa 5-25 part, Fructus Chaenomelis 10-30 part, Radix Paeoniae Alba 10-30 part, Herba Aristolochiae Mollissimae 5-20 part, Lignum Pini Nodi 5-25 part, Caulis Piperis Kadsurae 5-20 part, Rhizoma Chuanxiong 10-30 part, 6 parts, Radix Glycyrrhizae.
2. a kind of Chinese medicine composition for the treatment of osteoarthritis according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: the Radix Astragali 15 parts, Herba Erodii 10 parts, Herba Saussureae Involueratae 30 parts, Herba Epimedii 30 parts, Radix Callicarpae Bodinieri 15 parts, Herba Pyrolae 10 parts, Radix Oenotherae erythrosepalae 10 parts, Cortex schizophragmatis integrifolii radicis 20 parts, Coriolous Dersicolor (Fr.) Quel 10 parts, 30 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata 10 parts, Rhizoma Cibotii 20 parts, the Radix Angelicae Dahuricae 30 parts, Herba Ardisiae Japonicae 15 parts, Flos Rosae Chinensis 10 parts, 15 parts, careless Paeonia suffruticosa, Fructus Chaenomelis 20 parts, the Radix Paeoniae Alba 20 parts, Herba Aristolochiae Mollissimae 10 parts, Lignum Pini Nodi 15 parts, Caulis Piperis Kadsurae 10 parts, Rhizoma Chuanxiong 20 parts, 6 parts, Radix Glycyrrhizae.
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| CN103393840A (en) * | 2013-07-24 | 2013-11-20 | 赵世明 | Traditional Chinese medicine composition for treating osteoarthritis |
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| CN104958520A (en) * | 2015-07-25 | 2015-10-07 | 王璐 | Traditional Chinese medicine for treating osteoarthritis |
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