CN104606281A - Traditional Chinese medicine for treating viral hepatitis - Google Patents
Traditional Chinese medicine for treating viral hepatitis Download PDFInfo
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- CN104606281A CN104606281A CN201510055618.2A CN201510055618A CN104606281A CN 104606281 A CN104606281 A CN 104606281A CN 201510055618 A CN201510055618 A CN 201510055618A CN 104606281 A CN104606281 A CN 104606281A
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Abstract
The invention relates to a traditional Chinese medicine for treating viral hepatitis. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 15 parts of oriental wormwood, 20 parts of sedum sarmentosum, 10 parts of seed of feather cockscomb, 5 parts of akebiaquinata, 15 parts of Herba Hyperici Japonici, 8 parts of Lygodium japonicum and 25 parts of abrus cantoniensis hance. The clinical experiment proves that the traditional Chinese medicine can be used for safely and effectively treating the viral hepatitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of viral hepatitis.
Background technology
Viral hepatitis is a kind of infectious disease based on hepatic lesions caused by multiple hepatitis virus, has that infectiousness is strong, route of transmission is complicated, Epidemic Scope is extensive, sickness rate comparatively high.Clinically with loss of appetite, feel sick, epigastric discomfort, pain in the hepatic region, weak for main manifestations.Some patients can have jaundice heating and hepatomegaly with liver function injury.Some patient can chronicity, and even develop into liver cirrhosis, minority can develop into hepatocarcinoma.
Primary disease any age all can fall ill.Primary disease infectiousness is extremely strong, and disease is more serious to late complication.A lot of hepatitis does not recognize the hazardness of hepatitis, delays and does not control, finally threaten the life of patient.
Viral hepatitis belongs to global refractory disease, the Etiologic Classification of viral hepatitis, at present putative have first, second, third, fourth, penta 5 kinds of hepatitis viruss, write HAV, HBV, HCV, HDV, HEV respectively, except hepatitis B virus is DNA viruses, all the other are RNA viruses.Current western medicine has the antiviral class medicines such as interferon, lamivudine, famciclovir, and the immunomodulator such as thymosin α1 (Zadaxin), thymosin, immune ribonucleic acid, also have part liver-protecting medicine conbined usage, but its therapeutic effect is all undesirable and side effect is larger.
Primary disease belongs to the category such as the traditional Chinese medical science " hypochondriac pain ", " yellow cellulitis ", " deficient ", " acute jaundice ", " fulminant jaundice ", " the liver rump " according to its clinical manifestation.
Medical material present Research involved in the present invention is as follows:
Herba Artemisiae Scopariae [source] this product is the dry aerial parts of feverfew Artemisia scoparia Waldst. et Kit. Artemisia scoparia Waldst.et Kit. or Herba Artemisiae Scopariae Artemisia capillaris Thunb..Gather during the high 6 ~ 10cm of seedling in spring or autumn, alabastrum grew up to time tap, removing impurity and old stem, dry.The habit of gathering spring claims " capillary wormwood ", the title " Herba Artemisiae Scopariae " tapped autumn.[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns spleen, stomach, liver, gallbladder meridian.[function cures mainly] clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.[usage and dosage] 6 ~ 15g.
Herba Sedi [source] this product is the fresh or dry herb of crassulaceae plants Herba Sedi Sedum sarmentosum Bunge.Summer, Qiu Erji gather, removing impurity.Using fresh herb or drying.[nature and flavor] are sweet, light, cool.[return through] returns liver, gallbladder, small intestine meridian.[function cures mainly] eliminating damp-heat, removing toxic substances.For jaundice due to damp-heat, dysuria, carbuncle skin infection, acute hepatitis, chronic hepatitis.[usage and dosage] 15 ~ 30g.
Semen Celosiae [source] this product is the dry mature seed of amaranthaceous plant Herba Celosiae argenteae Celosia argentea L..Tap plant during fruit maturation in autumn or win fruit ear, drying, collecting seed, removing impurity.[nature and flavor] are bitter, are slightly cold.[return through] returns Liver Channel.[function cures mainly] liver heat removing, improving eyesight, nebula removing.For liver-heat conjunctival congestion, nebula of looking unfamiliar film, blurring of vision, dizziness due to liver-fire.[usage and dosage] 9 ~ 15g.
Caulis Akebiae [source] this product is Teng's stem of plants of Lardizabalaceae Caulis Akebiae, threeleaf akebia or Caulis Akebiae.Rattan starts result in 5 ~ 6 years after the transfer, and the old rattan of mowing portion, dries or dry in the fall.[nature and flavor] are bitter, cold.[return through] GUIXIN, spleen, kidney, small intestinal, urinary bladder channel.[function cures mainly] clearing away heat and promoting diuresis, blood circulation and channel invigorating.Red for red urine, stranguria with turbid discharge, edema; Irritable feverish sensation in the chest, larynx larynx pain, aphtha of the mouth and tongue; Rheumatic arthralgia, galactostasis, amenorrhea, dysmenorrhea.[usage and dosage] 3 ~ 6g.
Herba Hyperici Japonici [source] this product is the herb of Garcinia maingayii Herba Hyperici Japonici.To gather when spring, summer-flowering herb, dry or using fresh herb.[nature and flavor] sweet, bitter, cold.[return through] returns lung, liver, stomach warp.[function cures mainly] clearing away heat-damp and promoting diuresis, removing toxic substances, dissipating blood stasis for subsidence of swelling.Main jaundice due to damp-heat, has loose bowels, dysentery; Acute appendicitis, carbuncle furuncle and phyma poison, tonsillitis, aphtha, conjunctival congestion and swelling pain; Venom, traumatic injury.[usage and dosage] 15 ~ 30g.
Spora Lygodii [source] this product is the drying and ripening spore of Lygodiaceae plant Spora Lygodii Lygodium japonicum (Thunb.) Sw..Tap rattan leaf when autumn, spore did not come off, dry, crumple or lay spore, removing rattan leaf.[nature and flavor] are sweet, salty, cold.[return through] returns bladder, small intestine meridian.[function cures mainly] eliminating damp-heat, treating stranguria pain relieving.For pyretic stranguria, sand Stranguria, stranguria caused by urinary stone, stranguria with blood, stranguria marked by chyluria, Urethra astringent pain.[usage and dosage] 6 ~ 15g.
Herba Abri [source] this product is the dry Herb of leguminous plant abrus cantoniensis Hance Abrus cantoniensis Hance.The whole year all can excavate, removing silt, dry.[nature and flavor] sweet, micro-hardship, cool.[return through] returns liver, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, Shugan Zhitong.For jaundice, side of body rib does not relax, epigastric distending pain; Acute hepatitis, chronic hepatitis, mastitis.[usage and dosage] 15 ~ 30g.[attention] this product seed is poisonous, can not be used as medicine, and the used time all must extract soybean pod.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of viral hepatitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective Cure Viruses hepatitis.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a Chinese medicine for viral hepatitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Artemisiae Scopariae 15 parts, Herba Sedi 20 parts, Semen Celosiae 10 parts, Caulis Akebiae 5 parts, Herba Hyperici Japonici 15 parts, Spora Lygodii 8 parts, Herba Abri 25 parts.
Inventor thinks primary disease disease located in liver, relevant with internal organs such as liver, gallbladder, spleen, stomach, kidneys.Outer because experience the damp and hot heresy of epidemic disease poison, interior because deficiency of vital QI.Acute hepatitis, based on excess syndrome, mainly experiences toxic dampness and heat, pent-up taste, suffocating of liver and gall, caused by retardance mechanism of qi.The many simulataneous insufficiency and excessive of chronic hepatitis, mainly exopathogen is reluctant to leave, incoordination between the liver and spleen, caused by liver and kidney deficiency, caused by venation block.Cholestatic is also simulataneous insufficiency and excessive, is mainly damp and hotly reluctant to leave, and suffocating of liver and gall, caused by spleen deficiency and blood stasis.Hepatitis gravis disease is waited critical, and mainly epidemic disease poison is flourishing, fire-transformation dryness-transformation, and nutrient blood of caving in, closes in pathogenic heat, caused by vigour wish is de-.Treatment should be basic with replenishing QI to invigorate the spleen, damp eliminating of regulating the flow of vital energy, kidney tonifying tonify deficiency, easing the affected liver yin nourishing, eliminating fire and detoxication, therefore assembly is our.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and Patients with Viral Hepatitis 92 example of being in hospital altogether in inventor in April, 2010 ~ 2013 between year February, be divided into treatment group 50 example and matched group 42 example at random, treatment group man 32 example, female 18 example, 8 ~ 62 years old age, 28.6 years old mean age, the course of disease 1 ~ 4 year; Matched group man 20 example, female 22 example, 9 ~ 66 years old age, 27.4 years old mean age, the course of disease 1 ~ 6 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
1) acute hepatitis can have weak, heating, yellow cellulitis, indigestion and loss of appetite, Nausea and vomiting, hypochondriac pain, abdominal distention, hepatalgia, hepatomegaly etc.Chronic hepatitis is acute hepatitis protracted course of disease, and the course of disease exceedes half a year, can have the sings and symptoms of acute stage, also can have splenomegaly, liver palm, spider angioma etc., and also can have the outer multiple organ injury of liver, the most common is arthritis and chronic nephritis.Hepatitis gravis onset is hurried, yellow cellulitis is deepened rapidly, obviously smelly, drowsiness, the tic of bleeding tendency, hepatic atrophy, liver, agitation, delirium, stupor, oliguria or urine retention etc.Cholestatic hepatitis jaundice is heavier, and can have weak, skin pruritus, hepatomegaly, bowel movements, gastrointestinal symptom are lighter.2) liver function: acute hepatitis patients serum glutamate pyruvate transaminase (SGPT) continues to increase, and serum bilirubin increases; Chronic hepatitis patient liver function repeatedly or the positive such as persistent anomaly, thymol turbidity, zinc sulfate turbidity.Hepatitis gravis liver function grievous injury, serum bilirubin obviously increase, the reduction of prothrombin time significant prolongation, cholesterol, azotemia etc.Cholestatic hepatitis bilirubin direct higher sustainable several months or 1 year, serum alkaline phosphatase and γ mono-glutamyl transferase increase, glutamate pyruvate transaminase slightly raises or normally.3) detection of plasma inspection: hepatitis specific antigen-antibody is diagnosable and distinguish various hepatitis.4) liver puncture pathologic finding: have very large value to the diagnosis of various hepatitis; All just data can be obtained to the cause of disease of chronic hepatitis, the cause of disease, inflammatory conditions, fibrosis.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.8 weeks courses for the treatment of.
The oral reduced glutathion sheet of matched group (Chongqing Yao You pharmaceutical Co. Ltd), takes according to its description.8 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Effective: subjective symptoms disappears or is clearly better, and hepatosplenomegaly reduces or stablizes constant, and liver function ALT, AST, SB are down to normally;
Effective: subjective symptoms takes a turn for the better, and hepatosplenomegaly is stablized constant, liver function ALT, AST, SB decline, and comparatively treatment is front reduces by more than 50%, but abnormal;
Invalid: without changing, not reach above standard or disease progression person.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment viral hepatitis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Herba Artemisiae Scopariae 15 grams, Herba Sedi 20 grams, Semen Celosiae 10 grams, Caulis Akebiae 5 grams, Herba Hyperici Japonici 15 grams, Spora Lygodii 8 grams, Herba Abri 25 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of viral hepatitis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Herba Artemisiae Scopariae 15 grams, Herba Sedi 20 grams, Semen Celosiae 10 grams, Caulis Akebiae 5 grams, Herba Hyperici Japonici 15 grams, Spora Lygodii 8 grams, Herba Abri 25 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of viral hepatitis.Oral, daily once.
Specific embodiment 3
Take: Herba Artemisiae Scopariae 15 grams, Herba Sedi 20 grams, Semen Celosiae 10 grams, Caulis Akebiae 5 grams, Herba Hyperici Japonici 15 grams, Spora Lygodii 8 grams, Herba Abri 25 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of viral hepatitis.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. be used for the treatment of a Chinese medicine for viral hepatitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Artemisiae Scopariae 15 parts, Herba Sedi 20 parts, Semen Celosiae 10 parts, Caulis Akebiae 5 parts, Herba Hyperici Japonici 15 parts, Spora Lygodii 8 parts, Herba Abri 25 parts.
2. a kind of Chinese medicine being used for the treatment of viral hepatitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Artemisiae Scopariae 15 parts, Herba Sedi 20 parts, Semen Celosiae 10 parts, Caulis Akebiae 5 parts, Herba Hyperici Japonici 15 parts, Spora Lygodii 8 parts, Herba Abri 25 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of viral hepatitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Artemisiae Scopariae 15 parts, Herba Sedi 20 parts, Semen Celosiae 10 parts, Caulis Akebiae 5 parts, Herba Hyperici Japonici 15 parts, Spora Lygodii 8 parts, Herba Abri 25 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of viral hepatitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Artemisiae Scopariae 15 parts, Herba Sedi 20 parts, Semen Celosiae 10 parts, Caulis Akebiae 5 parts, Herba Hyperici Japonici 15 parts, Spora Lygodii 8 parts, Herba Abri 25 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105641168A (en) * | 2016-02-19 | 2016-06-08 | 周华增 | Medicine for treating viral hepatitis B and viral hepatitis C and preparation method of medicine |
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CN1554382A (en) * | 2003-12-23 | 2004-12-15 | 胡新国 | Medicine liqid for curing hepatopathy |
CN1704089A (en) * | 2004-05-29 | 2005-12-07 | 李怡初 | Hepatic disease treating medicine |
CN103845429A (en) * | 2014-03-02 | 2014-06-11 | 马青 | Traditional Chinese medicine for treating chronic hepatitis |
CN103961473A (en) * | 2013-01-24 | 2014-08-06 | 广西医科大学 | Liver protecting drug |
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2015
- 2015-02-01 CN CN201510055618.2A patent/CN104606281A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1554382A (en) * | 2003-12-23 | 2004-12-15 | 胡新国 | Medicine liqid for curing hepatopathy |
CN1704089A (en) * | 2004-05-29 | 2005-12-07 | 李怡初 | Hepatic disease treating medicine |
CN103961473A (en) * | 2013-01-24 | 2014-08-06 | 广西医科大学 | Liver protecting drug |
CN103845429A (en) * | 2014-03-02 | 2014-06-11 | 马青 | Traditional Chinese medicine for treating chronic hepatitis |
Non-Patent Citations (1)
Title |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105641168A (en) * | 2016-02-19 | 2016-06-08 | 周华增 | Medicine for treating viral hepatitis B and viral hepatitis C and preparation method of medicine |
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