CN104587409A - Lipid-lowering and meridian-dredging medicament for patients with hyperlipidemia and preparation method thereof - Google Patents

Abstract

The invention discloses a lipid-lowering and meridian-dredging medicament for patients with hyperlipidemia. The lipid-lowering and meridian-dredging medicament is mainly prepared from the following raw material medicines in parts by weight: 10-20 parts of radix puerariae, 6-9 parts of branches and leaves of peanuts, 10-20 parts of lotus leaves, 5-10 parts of actinodaphne obocata, 6-12 parts of erigeron breviscapus, 8-14 parts of semen raphani, 9-16 parts of hawthorn, 10-15 parts of malt, 7-12 parts of oriental wormwood, 5-10 parts of ginkgo leaves, 6-9 parts of apium graveolens, 10-15 parts of curcuma aromatica, 15-20 parts of semen cuscutae, 8-10 parts of calcined oyster shells, 6-9 parts of kelp, 4-8 parts of radix scrophulariae and 5-9 parts of air potato. The lipid-lowering and meridian-dredging medicament disclosed by the invention is searched according to the principle of traditional Chinese medicines, and is scientific in material selection, accurate in proportioning and reliable in curative effect; the formula disclosed by the invention has the effects of tonifying spleen and eliminating dampness, suppressing yang and nourishing yin, reducing phlegm and lowering lipids, and the like, and the product prepared by the formula disclosed by the invention is wide in applicability, remarkable in curative effect, safe and free from side effects.

Description

Hyperlipemia lowering fat to dredge vessels medicament and preparation

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of hyperlipemia lowering fat to dredge vessels medicament and preparation.

Background technology

Because lipid metabolism or running make one or more lipids of blood plasma higher than being normally called hyperlipemia extremely, lipid is insoluble or be slightly soluble in water and must exist with lipoprotein form with protein bound, therefore, hyperlipemia is often hyperlipoproteinemia, and blood fat mainly refers to cholesterol in serum and triglyceride.No matter be that cholesterol level increases, or the content of triglyceride increases, or both all increase, and are referred to as hyperlipemia.The main harm of hyperlipidemia causes atherosclerosis, and then cause numerous relevant diseases, and wherein modal a kind of fatal disease is exactly coronary heart disease.Thick and the nonindependence disease of blood, but have a lot of disease clinically, as all thick close relations with blood such as arteriosclerosis, cerebral thrombosis, myocardial infarction, hypertension, diabetes, obstructive retinitis and Chronic Liver kidney diaseases.This is because when the blood viscosity of people increases, velocity of blood flow slows down, the oxygen that body tissue obtains is relative with nutrient substance to be reduced, particularly too much erythrocytic aging, sclerosis, there is red cell conglomeration, increase the weight of blood thick and blood coagulation occurs, occurring blood coagulation block, cause blood vessel embolism, thus ischemic Cardial or cerebral vascular diseases occurs.Long-term hyperlipidemia can cause hyperlipidemia, blood vessel wall slowly adheres to a lot of metabolite, and vessel wall elasticity reduces, simultaneously the logical blood reduced capability of blood vessel, blood transportation nutrient and oxygen ability reduce, a lot of organ can not get normal nutrition and oxygen supply, and organ dysfunction is impaired gradually, and impaired is the body of gland organ that blood vessel is less at first, long-term blood fat height also can cause the environment of blood to degenerate, a lot of immunocyte cannot be survived, and slowly disappears, and causes immunity to reduce.Be divided into two classes clinically: 1. constitutional, rare, belong to heritability disorders of lipid metabolism disease; 2. Secondary cases, is common in and controls bad diabetes, to drink, hypothyroidism, nephrotic syndrome, Rend dialysis, renal transplantation, biliary obstruction, oral contraceptive etc.Constitutional person sees child, Secondary cases person is many 20 years old sequela, majority are asymptomatic only to be found when health check-up, also coronary heart disease and other atherosclerosis can be there is in one's early years as apoplexy, peripheral angiopathy, often with obesity, impaired glucose tolerance (or diabetes), hyperinsulinemia, hyperuricemia etc.Western medical treatment method is long-term Comprehensive Treatment, emphasizes to keep on a diet and physical training is master, and when effect is undesirable, assistant is with the treatment of bile acid-binding resin class, nicotinic acid class and fibrate drug.Secondary cases person's (as diabetes, hypothyroidism), then answer Cure the Primary Disease.Publication number CN 103432522 A(application number 201310376788.1) Chinese patent literature disclose a kind of Chinese medicine formula for the treatment of hyperlipidemia, composition have Rhizoma Alismatis, Rhizoma Polygonati, Radix Polygoni Multiflori, Semen Trigonellae, Semen Cassiae, the Cortex Eucommiae, Fructus Crataegi, Rhizoma Curcumae Longae, Folium Nelumbinis, Radix Salviae Miltiorrhizae, Semen sojae atricolor, Fructus Jujubae.Publication number CN 103432391 A(application number 201310387337.8) Chinese patent literature disclose a kind of medicine for the treatment of hyperlipidemia and preparation method thereof, prepared by Pericarpium Citri Reticulatae, Fructus Crataegi, Rhizoma Alismatis, Poria, Rhizoma Polygonati, Radix Salviae Miltiorrhizae, Radix Polygoni Multiflori etc.Publication number CN 103536791 A(application number 201310509540.8) Chinese patent literature disclose a kind of Chinese medicine for the treatment of hyperlipidemia, be made up of emblic leafflower fruit 13 parts, Miscanthus floridulus (Labill.) Warb. 12 parts, Herba ophiorrhizae japonicae 14 parts, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 12 parts, pistachio 10 parts, 8 parts, golden lion rattan, Herba Dicranostigmatis Leptopodi 8 parts, caephalotaxus sinensis 14 parts, Radix Actinidiae Erianthae 16 parts, Mazus japonicus 15 parts, Sonerila picta Korth. 12 parts, Herba Sarcopyramis nepalensis 14 parts, thick stem Radix Hemsleyae Macrospermae 14 parts, Radix premnae ligustroidis 12 parts, 14 parts, shark's fin wood, Radix Aristolochiae Kaempferi 12 Fen, Folium Clerodendri japonici 14 parts, tongue spray 10 parts etc.

Current, the Chinese medicine and western medicine being used for the treatment of hyperlipidemia has many, but the therapeutic effect of these medicines can not meet the requirement of people, and side effect is large, has injury to Liver and kidney, therefore, needs to develop the Chinese medicine formula of the little or nothing of a kind of eutherapeutic side effect.

Summary of the invention

For the deficiencies in the prior art, the object of this invention is to provide a kind of hyperlipemia lowering fat to dredge vessels medicament that is safe and effective, that easily take for a long time and preparation.

Technical scheme of the present invention is:

Hyperlipemia lowering fat to dredge vessels medicament, is prepared from primarily of following bulk drugs, is weight portion: Radix Puerariae 10-20, Caulis et Folium Arachidis hypogaeae 6-9, Folium Nelumbinis 10-20, Rhizoma Arisaematis 5-10, Herba Erigerontis 6-12, Semen Raphani 8-14, Fructus Crataegi 9-16, Fructus Hordei Germinatus 10-15, Herba Artemisiae Scopariae 7-12, Folium Ginkgo 5-10, Herba Apii graveolentis 6-9, Radix Curcumae 10-15, Semen Cuscutae 15-20, Concha Ostreae (calcined) 8-10, Thallus Laminariae (Thallus Eckloniae) 6-9, Radix Scrophulariae 4-8, Rhizoma Dioscoreae Bulbiferae 5-9.

In preferred scheme, Radix Puerariae 12-18, Caulis et Folium Arachidis hypogaeae 7-8, Folium Nelumbinis 12-18, Rhizoma Arisaematis 6-9, Herba Erigerontis 8-10, Semen Raphani 10-12, Fructus Crataegi 11-14, Fructus Hordei Germinatus 11-14, Herba Artemisiae Scopariae 8-11, Folium Ginkgo 7-8, Herba Apii graveolentis 7-8, Radix Curcumae 11-14, Semen Cuscutae 16-19, Concha Ostreae (calcined) 8.5-9.5, Thallus Laminariae (Thallus Eckloniae) 7-8, Radix Scrophulariae 5-7, Rhizoma Dioscoreae Bulbiferae 6-8.

Be more preferably, Radix Puerariae 15, Caulis et Folium Arachidis hypogaeae 7.5, Folium Nelumbinis 15, Rhizoma Arisaematis 7.5, Herba Erigerontis 9, Semen Raphani 11, Fructus Crataegi 12.5, Fructus Hordei Germinatus 12.5, Herba Artemisiae Scopariae 9.5, Folium Ginkgo 7.5, Herba Apii graveolentis 7.5, Radix Curcumae 12.5, Semen Cuscutae 17.5, Concha Ostreae (calcined) 9, Thallus Laminariae (Thallus Eckloniae) 7.5, Radix Scrophulariae 6, Rhizoma Dioscoreae Bulbiferae 7.

The preparation method of described hyperlipemia lowering fat to dredge vessels medicament decoction is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Radix Puerariae, Fructus Crataegi, Fructus Hordei Germinatus and Herba Apii graveolentis decontamination, clean, dry, pulverize, obtained medicated powder;

(4) by Concha Ostreae (calcined) decontamination, break into pieces, put into pot, after decocting with water 30 minutes, add Caulis et Folium Arachidis hypogaeae, Folium Nelumbinis, Rhizoma Arisaematis, Herba Artemisiae Scopariae, Folium Ginkgo, Radix Curcumae, Semen Cuscutae, Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae, Rhizoma Dioscoreae Bulbiferae and step (1) (2) made crude drug, after boiling, a turn little fire decocts 20-50 minute, and (preferred, 30-40 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 35 minutes), filter, collect filtrate;

(5) step (3) made medicated powder is joined in step (4) gained filtrate while hot, stir, obtain decoction.

The preparation method of described hyperlipemia lowering fat to dredge vessels medicament decoction, step (4) amount of water is that doubly (preferred, amount of water is 7-8 times of whole crude drug quality to the 6-9 of whole crude drug quality; Be more preferably, amount of water is 7.5 times of whole crude drug quality).

The preparation method of described powder is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Caulis et Folium Arachidis hypogaeae and Folium Ginkgo, remove impurity, is placed in frying pan, fries and has burnt brown macules to surface, and spray vinegar, takes out, dry;

(4) by Radix Puerariae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Concha Ostreae (calcined), Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae decontamination, clean, dry, pulverize together with step (1) (2) (3) made crude drug, mix with sucrose, pulverize and sieve, obtain powder.

The preparation method of described hyperlipemia lowering fat to dredge vessels medicament powder, step (4) was pulverized 120-200 mesh sieve and (preferably, was pulverized 140-180 mesh sieve; Be more preferably, pulverized 160 mesh sieves).

The preparation method of described capsule is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Caulis et Folium Arachidis hypogaeae and Folium Ginkgo, remove impurity, is placed in frying pan, fries and has burnt brown macules to surface, and spray vinegar, takes out, dry;

(4) by Radix Puerariae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Concha Ostreae (calcined), Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae decontamination, clean, dry, pulverize together with step (1) (2) (3) made crude drug, mixing, add starch slurry and Icing Sugar, make soft material, granulate, dry, granulate, incapsulates every 0.4g, obtains capsule.

The preparation method of described hyperlipemia lowering fat to dredge vessels drug capsule, step (4) was granulated 12-16 mesh sieve (preferred, 14 mesh sieves of granulating).

The preparation method of described granule is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Concha Ostreae (calcined) decontamination, break into pieces, put into pot, add the soak by water of whole crude drug quality 7.5 times after 30 minutes, add Radix Puerariae, Caulis et Folium Arachidis hypogaeae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Folium Ginkgo, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae, Rhizoma Dioscoreae Bulbiferae and step (1) (2) made crude drug, after boiling, turn little fire and decoct, filter, collect filtrate;

(4) heating of step (3) gained filtrate is boiled into clear paste, adds dextrin, drying under reduced pressure, pulverize, guiding humid medium, soft material processed, granulate, 70 DEG C of dryings, granulate, obtains granule

The preparation method of described hyperlipemia lowering fat to dredge vessels medicament granule, step (3) turn little fire decocts 20-50 minute, and (preferred, 30-40 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 35 minutes).

The Chinese medicine composition for the treatment of hyperlipidemia provided by the invention, scientific formulation, multiple dosage form preparation is simple, is easy to carry.In addition, excellent results of the present invention also shows:

1, the present invention develops according to Chinese medicine principle, science selection, accurate proportioning, and curative effect is reliable;

2, formula of the present invention has invigorating spleen to remove dampness, YANG hyperactivity suppressing nourishing YIN, effects such as blood fat reducing of reducing phlegm;

3, the products made thereby suitability of the present invention is wide, evident in efficacy, and safety has no side effect.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.

embodiment 1hyperlipemia lowering fat to dredge vessels medicament, is prepared from (every part of 6g) primarily of following bulk drugs: Radix Puerariae 10 parts, Caulis et Folium Arachidis hypogaeae 6 parts, 10 parts, Folium Nelumbinis, Rhizoma Arisaematis 5 parts, Herba Erigerontis 6 parts, Semen Raphani 8 parts, Fructus Crataegi 9 parts, 10 parts, Fructus Hordei Germinatus, Herba Artemisiae Scopariae 7 parts, Folium Ginkgo 5 parts, Herba Apii graveolentis 6 parts, Radix Curcumae 10 parts, Semen Cuscutae 15 parts, Concha Ostreae (calcined) 8 parts, Thallus Laminariae (Thallus Eckloniae) 6 parts, Radix Scrophulariae 4 parts, Rhizoma Dioscoreae Bulbiferae 5 parts.

The preparation method of above-mentioned hyperlipemia lowering fat to dredge vessels medicament decoction is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Radix Puerariae, Fructus Crataegi, Fructus Hordei Germinatus and Herba Apii graveolentis decontamination, clean, dry, pulverize, obtained medicated powder;

(4) by Concha Ostreae (calcined) decontamination, break into pieces, put into pot, add the soak by water of whole crude drug quality 7.5 times after 30 minutes, add Caulis et Folium Arachidis hypogaeae, Folium Nelumbinis, Rhizoma Arisaematis, Herba Artemisiae Scopariae, Folium Ginkgo, Radix Curcumae, Semen Cuscutae, Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae, Rhizoma Dioscoreae Bulbiferae and step (1) (2) made crude drug, after boiling, turn little fire and decoct 35 minutes, filter, collect filtrate;

(5) step (3) made medicated powder is joined in step (4) gained filtrate while hot, stir, obtain decoction.

The instructions of taking of decoction of the present invention: decoction is 14 days courses for the treatment of, takes every day 3 times (warm), each 50m1-100m1.

embodiment 2hyperlipemia lowering fat to dredge vessels medicament, is prepared from (every part of 6g) primarily of following bulk drugs: Radix Puerariae 20 parts, Caulis et Folium Arachidis hypogaeae 9 parts, 20 parts, Folium Nelumbinis, Rhizoma Arisaematis 10 parts, Herba Erigerontis 12 parts, Semen Raphani 14 parts, Fructus Crataegi 16 parts, 15 parts, Fructus Hordei Germinatus, Herba Artemisiae Scopariae 12 parts, Folium Ginkgo 10 parts, Herba Apii graveolentis 9 parts, Radix Curcumae 15 parts, Semen Cuscutae 20 parts, Concha Ostreae (calcined) 10 parts, Thallus Laminariae (Thallus Eckloniae) 9 parts, Radix Scrophulariae 8 parts, Rhizoma Dioscoreae Bulbiferae 9 parts.

The preparation method of hyperlipemia lowering fat to dredge vessels medicament powder is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Caulis et Folium Arachidis hypogaeae and Folium Ginkgo, remove impurity, is placed in frying pan, fries and has burnt brown macules to surface, and spray vinegar, takes out, dry;

(4) by Radix Puerariae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Concha Ostreae (calcined), Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae decontamination, clean, dry, pulverize together with step (1) (2) (3) made crude drug, mix with sucrose, pulverize 160 mesh sieves, obtain powder.

Model case: xxx, female, 52 years old.Main suit: nearest one week, without the appearance giddy of obvious inducement, tinnitus, luxated tooth, with soreness of the waist and knees, coldness of the body and aversion to cold, body and the spirit fails, forgetful, medical check, blood fat result shows, serum cholesterol 6.71mmol/L, triglyceride 2.01mmol/L, HDL-C 1.98mmol/L, low-density lipoprotein cholesterol 3.64mmol/L, is diagnosed as hyperlipidemia.

Take the present embodiment gained hyperlipemia lowering fat to dredge vessels medicament powder, each one bag (about 4-6g), every day 3 times, warm boiled water, 14 days courses for the treatment of.After taking one week, the symptom that feels uneasy takes a turn for the better to some extent, and after taking a course for the treatment of, the malaise symptoms such as tinnitus, luxated tooth disappears substantially, dizzy degree obviously alleviates, after continuing to take two courses for the treatment of, patient is without malaise symptoms, and hospital checks, blood fat is down to normal range, hepatic and renal function is normal, and follow up a case by regular visits in 1 year, patient does not have recurrence.

embodiment 3hyperlipemia lowering fat to dredge vessels medicament, is prepared from (every part of 6g) primarily of following bulk drugs: Radix Puerariae 12 parts, Caulis et Folium Arachidis hypogaeae 7 parts, 12 parts, Folium Nelumbinis, Rhizoma Arisaematis 6 parts, Herba Erigerontis 8 parts, Semen Raphani 10 parts, Fructus Crataegi 11 parts, 11 parts, Fructus Hordei Germinatus, Herba Artemisiae Scopariae 8 parts, Folium Ginkgo 7 parts, Herba Apii graveolentis 7 parts, Radix Curcumae 11 parts, Semen Cuscutae 16 parts, Concha Ostreae (calcined) 8.5 parts, Thallus Laminariae (Thallus Eckloniae) 7 parts, Radix Scrophulariae 5 parts, Rhizoma Dioscoreae Bulbiferae 6 parts.

The preparation method of hyperlipemia lowering fat to dredge vessels drug capsule agent is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Caulis et Folium Arachidis hypogaeae and Folium Ginkgo, remove impurity, is placed in frying pan, fries and has burnt brown macules to surface, and spray vinegar, takes out, dry;

(4) by Radix Puerariae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Concha Ostreae (calcined), Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae decontamination, clean, dry, pulverize together with step (1) (2) (3) made crude drug, mixing, add starch slurry and Icing Sugar, make soft material, cross 14 mesh sieves and granulate, dry, granulate, incapsulates every 0.4g, obtains capsule.

Model case: xxx, man, 55 years old.Before 4 years, find during health check-up, T-CHOL 7.02mmol/L, triglyceride 2.13mmol/L is higher, is diagnosed as hyperlipidemia, has dizzy, headache, the symptom such as cardiopalmus, tinnitus, have difficulty in going to sleep in the evening, dysphoria with feverish sensation in the chest palms and soles, forgetfully day by day increases the weight of, between olympiad, intermittently took many lipid lowerers, but therapeutic effect is all undesirable, patient loses treatment confidence.

Introduce by friend and take the agent of the present embodiment gained hyperlipemia lowering fat to dredge vessels drug capsule, every day 3 times, each 3-5, with warm water delivery service, 14 days courses for the treatment of.After taking a course for the treatment of, the symptom such as patient's self-induction is dizzy, headache takes a turn for the better, and continues to take two courses for the treatment of afterwards, and patient's malaise symptoms all disappears, after having taken the 4th course for the treatment of, check of seeking medical advice, blood fat returns to normal range, other indices of health are also all normal, and follow up a case by regular visits in 2 years, patient is not recurred.

embodiment 4hyperlipemia lowering fat to dredge vessels medicament, is prepared from (every part of 6g) primarily of following bulk drugs: Radix Puerariae 18 parts, Caulis et Folium Arachidis hypogaeae 8 parts, 18 parts, Folium Nelumbinis, Rhizoma Arisaematis 9 parts, Herba Erigerontis 10 parts, Semen Raphani 12 parts, Fructus Crataegi 14 parts, 14 parts, Fructus Hordei Germinatus, Herba Artemisiae Scopariae 11 parts, Folium Ginkgo 8 parts, Herba Apii graveolentis 8 parts, Radix Curcumae 14 parts, Semen Cuscutae 19 parts, Concha Ostreae (calcined) 9.5 parts, Thallus Laminariae (Thallus Eckloniae) 8 parts, Radix Scrophulariae 7 parts, Rhizoma Dioscoreae Bulbiferae 8 parts.

The preparation method of hyperlipemia lowering fat to dredge vessels medicament granule is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Concha Ostreae (calcined) decontamination, break into pieces, put into pot, add the soak by water of whole crude drug quality 7.5 times after 30 minutes, add Radix Puerariae, Caulis et Folium Arachidis hypogaeae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Folium Ginkgo, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae, Rhizoma Dioscoreae Bulbiferae and step (1) (2) made crude drug, after boiling, turn little fire and decoct 35 minutes, filter, collect filtrate;

(4) heating of step (3) gained filtrate is boiled into clear paste, adds dextrin, drying under reduced pressure, pulverize, guiding humid medium, soft material processed, granulate, 70 DEG C of dryings, granulate, obtains granule

Model case: xxx, man, 63 years old.Over one month, patient feels dizziness, cardiopalmus, breast side of body feeling of distension and oppression often, and have a sleepless night in the evening, daytime weak asthenia, the few tongue of red tongue, deep-thready pulse, medical check, patient's private prosecution suffers from coronary heart disease 5 years, has medication treatment always, finds through every inspection, patients with lipid is higher, T-CHOL is up to 6.99mmol/L, and triglyceride is 1.32mmol/L, is diagnosed as coronary heart disease and merges hyperlipidemia.

Take the present embodiment gained hyperlipemia lowering fat to dredge vessels medicament granule, the medicine cutting out treatment coronary heart disease adopts every day 3 times, each one bag (about 4-6g), with warm boiled water, and 14 days courses for the treatment of.After taking a course for the treatment of, patient's dizziness and cardiopalmus symptom are obviously improved, after taking three courses for the treatment of, malaise symptoms disappears completely, and consolidate after taking two courses for the treatment of, patient's self-induction is fully recovered, check, check result shows, and T-CHOL is down to 4.82mmol/L, and triglyceride is 1.24mmol/L, patient fully recovers, the angina pectoris of electrocardiogram display patient also improves, and follow up a case by regular visits in 1 year, patient is not recurred.

embodiment 5hyperlipemia lowering fat to dredge vessels medicament, is prepared from (every part of 6g) primarily of following bulk drugs: Radix Puerariae 15 parts, Caulis et Folium Arachidis hypogaeae 7.5 parts, 15 parts, Folium Nelumbinis, Rhizoma Arisaematis 7.5 parts, Herba Erigerontis 9 parts, Semen Raphani 11 parts, Fructus Crataegi 12.5 parts, 12.5 parts, Fructus Hordei Germinatus, Herba Artemisiae Scopariae 9.5 parts, Folium Ginkgo 7.5 parts, Herba Apii graveolentis 7.5 parts, Radix Curcumae 12.5 parts, Semen Cuscutae 17.5 parts, Concha Ostreae (calcined) 9 parts, Thallus Laminariae (Thallus Eckloniae) 7.5 parts, Radix Scrophulariae 6 parts, Rhizoma Dioscoreae Bulbiferae 7 parts.

The preparation method of hyperlipemia lowering fat to dredge vessels medicament decoction is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Radix Puerariae, Fructus Crataegi, Fructus Hordei Germinatus and Herba Apii graveolentis decontamination, clean, dry, pulverize, obtained medicated powder;

(4) by Concha Ostreae (calcined) decontamination, break into pieces, put into pot, add the soak by water of whole crude drug quality 7.5 times after 30 minutes, add Caulis et Folium Arachidis hypogaeae, Folium Nelumbinis, Rhizoma Arisaematis, Herba Artemisiae Scopariae, Folium Ginkgo, Radix Curcumae, Semen Cuscutae, Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae, Rhizoma Dioscoreae Bulbiferae and step (1) (2) made crude drug, after boiling, turn little fire and decoct 35 minutes, filter, collect filtrate;

(5) step (3) made medicated powder is joined in step (4) gained filtrate while hot, stir, obtain decoction.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Radix Puerariae: base is former: be the dry root of legume pueraria lobata or Radix Puerariae rattan.Nature and flavor: sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.

Caulis et Folium Arachidis hypogaeae: base is former: be the stem and leaf of leguminous plant Semen arachidis hypogaeae.Nature and flavor: sweet light; Flat.Gui Jing: Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, blood pressure lowering of allaying excitement.Main traumatic injury, carbuncle sore tumefacting virus, insomnia, hypertension.

Folium Nelumbinis: base is former: be the leaf of nymphaeaceae plant lotus.Nature and flavor: bitter are flat.Gui Jing: return liver, spleen, stomach warp.Function cures mainly: clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding.For multiple hemorrhage and puerperal blood faints.

Rhizoma Arisaematis: base is former: for Bryaceae plant warms up the plant of ground great Ye moss.Nature and flavor: pungent; Bitter; Flat.Function cures mainly: tranquilizing by nourishing the heart; Liver heat removing and eyesight improving.Main severe palpitation; Neurasthenia; Conjunctival congestion and swelling pain; Coronary heart disease; Hypertension etc.

Herba Erigerontis: base is former: be the herb of chrysanthemum kind of plant Erigeron breviscapus (Vant.) Hand.-Mazz..Nature and flavor: pungent, micro-hardship, temperature.Gui Jing: return lung; Stomach; Tripe warp.Function cures mainly: expelling cold and relieving exterior syndrome, expelling wind and removing dampness, activating collaterals to relieve pain.For headache due to common cold, toothache, stomachache, rheumatalgia, the paralysis that cerebrovas-cularaccident causes, osteomyelitis.

Semen Raphani: base is former: be the dry mature seed of crucifer Radix Raphani.Nature and flavor: pungent, sweet are flat.Gui Jing: return lung, spleen, stomach warp.Function cures mainly: help digestion de-swelling, lowering the adverse-rising QI to resolve phlegm.For retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.

Fructus Crataegi: base is former: be the dry mature fruit of rosaceous plant Fructus Pyri Pashiae or Fructus Crataegi.Nature and flavor: sour, sweet, tepor.Gui Jing: return spleen, stomach, Liver Channel.Function cures mainly: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.

Fructus Hordei Germinatus: base is former: for the mature fruit of grass Fructus Hordei Vulgaris obtains through germination.Nature and flavor: sweet are flat.Gui Jing: return spleen, stomach warp.Function cures mainly: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans.

Herba Artemisiae Scopariae: base is former: this product is the dry aerial parts of feverfew Artemisia scoparia Waldst. et Kit. or Herba Artemisiae Scopariae.Nature and flavor: bitter, pungent, are slightly cold.Gui Jing: return spleen, stomach, liver, gallbladder meridian.Function cures mainly: clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.

Folium Ginkgo: base is former: the blade of Ginkgoaceae plant Ginkgo biloba.Nature and flavor: bitter; Sweet; Puckery; Property is put down; Mild toxicity.Gui Jing: the heart; Lung; Spleen channel.Function cures mainly: invigorate blood circulation and nourish heart, astringing intestine to stop diarrhea of astringing the lung.Main obstruction of qi in the chest and cardialgia; To breath with cough phlegmatic cough; Dysentery; Leucorrhea

Herba Apii graveolentis: base is former: be the herb of samphire Herba Apii graveolentis.Nature and flavor: sweetness and bitterness are cool.Gui Jing: " book on Chinese herbal medicine brief points ": " enter bright, the JUE YIN meridian of foot sun." function cures mainly: calming liver and clearing heat, expelling wind and removing dampness.Control hypertension, dizziness and headache, flushing conjunctival congestion, stranguria with blood, carbuncle.

Radix Curcumae: base is former: be the tuber of zingiberaceous plant Rhizoma Curcumae Longae, Radix Curcumae or Rhizoma Curcumae.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, the heart, lung meridian.Function cures mainly: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.

Semen Cuscutae: base is former: be the dry mature seed of convolvulus cuscuta plant.Nature and flavor: sweet, temperature.Gui Jing: return liver,kidney,spleen warp.Function cures mainly: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.

Concha Ostreae (calcined): base is former: be the shell of the long Concha Ostreae of Ostreidae animal, Dalian Bay Concha Ostreae or Crassostrea rivularis.Concha Ostreae (calcined): by the Concha Ostreae cleaned, put on smokeless stove fire and be calcined to canescence, taking-up cools, and pulverizes.Nature and flavor: salty, are slightly cold.Gui Jing: return liver, gallbladder, kidney channel.Function cures mainly: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.

Thallus Laminariae (Thallus Eckloniae): base is former: be the dry thallus of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) or Alariaceae plant Thallus Laminariae (Thallus Eckloniae) (goose palm dish).Nature and flavor: salty, cold.Gui Jing: return liver, stomach, kidney channel.Function cures mainly: hard masses softening and resolving, expectorant, diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema.

Radix Scrophulariae: base is former: be goatweed Radix Scrophulariae. dry root.Nature and flavor: sweet, bitter, salty, are slightly cold.Gui Jing: return lung, stomach, kidney channel.Function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.

Rhizoma Dioscoreae Bulbiferae: base is former: be the tuber of Dioscoreaceae plant Dioscorea bulbifera L..Nature and flavor: bitter, pungent, cool.Slightly poisonous.Gui Jing: " Bencao Jingshu ": " start with few the moon, meridian of Foot-JUE YIN." function cures mainly: removing toxic substances and promoting subsidence of swelling, dissipating phlegm and resolving masses, cooling blood for hemostasis.For thyromegaly, tuberculous lymphadenitis, laryngopharynx swelling and pain, spits blood, spitting of blood, pertussis, cancerous protuberance; Furuncle is controlled in external.

test example 1for verifying the curative effect of gained hyperlipemia lowering fat to dredge vessels medicament (embodiment 5) of the present invention, carry out clinical trial

Physical data: in January, 2012 in December ,-2013, filter out from hospital outpatient and in-patient department the patient that 453 examples are diagnosed as hyperlipidemia, wherein women 241 example, male 212 example, age 32-77 year, 52.5 years old mean age, average course of disease 27.3 months.Wherein serum total cholesterol (TC) increases 282 examples, and triglyceride (TG) increases 237 examples, and low-density lipoprotein cholesterol (LDL-C) increases 121 examples, and HDL-C (HDL-C) reduces by 149 examples.

Diagnostic criteria: dizzy, breast side of body feeling of distension and oppression, pareordia twinge, cardiopalmus, spiritlessness and weakness, extremities being not warm, distension and fullness in the abdomen, indigestion and loss of appetite loose stool, soreness of the waist and knees, the few tongue of red tongue, thready and rapid pulse, light red tongue is fat, deficient pulse or weak, greasy fur, rolling pulse or moisten, the dark or petechia of purplish tongue or ecchymosis or sublingual varicosis, hesitant pulse.In normal diet situation, blood lipid level serum total cholesterol (TC) >=5.72 mmol/L after fasting 12 ~ 14 h is detected at least 2 times in 2 weeks, or triglyceride (TG) >=1.70 mmol/L, accompany or do not accompany HDL-C (HDL-C)≤0.91 mmol/L, or though original hyperlipemia takes fat-reducing medicament, but drug withdrawal more than 2 weeks, and blood fat still meets above-mentioned standard.

Discharge standard: 1, do not meet above-mentioned Western medicine diagnose standard and TCM syndrome diagnostic criteria person; 2, advanced heart failure, cardiac function belong to IV grade of person; 3, due to the important organ such as kidney, the liver nonfunction person that causes heart failure; 4, gestation or just preparing gestation and women breast-feeding their children; 5, the severe primary diseases such as liver, kidney, hemopoietic system are merged, renal dysfunction person; 6, all factors that can increase mortality rate: as cardiogenic shock, serious ventricular arrhythmia, dissociation, obstructive myocardiosis, the valvular heart disease do not repaired, constrictive pericarditis, pericardial tamponade, pulmonary infarction, has obvious the infected, and does not have the hypertension of control; 7, allergic constitution or those who are allergic to this drug, glaucoma patient; 8, cannot judge that curative effect or data are not congruent to affect the treatment or safety judgement person.

Patient is divided into two groups at random, experimental group 313 example and matched group 140 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, take every day twice (warm), each 50m1-100m1(adjusts to some extent depending on concrete condition), 14 days courses for the treatment of, matched group takes other medicine (conventional medication such as enalapril maleate sheet, fenofibrate, Xuezhikang, Bayaspirin Enteric-coated, profit pressure peptide).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.Treat four courses for the treatment of, measure blood fat (TC, TG, HDL-C, LDL-C) situation before and after treatment.

Curative effect situation criterion: formulate according to " new Chinese medicine guideline of clinical investigations ", cure: clinical malaise symptoms disappears completely, the every inspection of laboratory recovers normal: effective: clinical malaise symptoms is clearly better or primary symptom disappears substantially, and lipids detection reaches TC decline >=20% or TG >=40% or HDL rising >=0.26 mmol/L and meets any one; Effective: clinical malaise symptoms takes a turn for the better, and 10%≤TC decline <, 20% or 20%≤TG decline < 40% or 0.104 mmol/L≤HDL-C rising < 0.26 mmol/L meets any one; Invalid: clinical malaise symptoms is not clearly better, lipids detection does not reach effective standard.(recovery from illness number of cases+effective number of cases+effectively number of cases)/patient total number of cases × 100%=total effective rate

Table 1 liang group patient treatment outcome

Two groups of therapeutic outcomes are as table 1, therefrom known: experimental group patient, healing have 116 examples (37.1%), effective patient 128 example (40.9%), effective patient 63 example (20.1%), experimental group total effective rate 98.1%.The healing example of matched group, effective example and effectively example be respectively 40(28.6%), 36(25.7%) and 44(31.4%), the total effective rate of matched group is 85.7%, and therapeutic effect is starkly lower than experimental group.More several conventional medicine of the therapeutic effect of visible products obtained therefrom of the present invention to hyperlipidemia is good.

Blood lipid level situation of change (`x ± s, mmol/L) before and after table 2 liang group treatment

Compare two groups of patient's cholesterol, triglyceride, high density lipoprotein and low density lipoprotein, LDL (the results are shown in Table 2) further, good compared with matched group of the average improvement situation of known experimental group patient, the reduction effect wherein for cholesterol and triglyceride is comparatively remarkable.All there is not untoward reaction in treatments period experimental group patient, illustrates that the present invention has the advantage of safe without toxic side effect.

In formula of the present invention, the Radix Puerariae expelling pathogenic factors from muscles for reducing heat of selection; Caulis et Folium Arachidis hypogaeae heat-clearing and toxic substances removing, blood pressure lowering of allaying excitement; Folium Nelumbinis clearing away summer-heat, sending up the lucid YANG; Rhizoma Arisaematis tranquilizing by nourishing the heart, liver heat removing and eyesight improving; Herba Erigerontis falls apart wind heat clearing away, suppressing the hyperactive liver improving eyesight; Semen Raphani helps digestion de-swelling, lowering the adverse-rising QI to resolve phlegm; Hawthorn digesting stomach invigorating, circulation of qi promoting dissipating blood stasis; Fructus Hordei Germinatus promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite; Herba Artemisiae Scopariae clearing away damp-heat, jaundice eliminating subcutaneous ulcer; Folium Ginkgo invigorate blood circulation nourish heart, astringing intestine to stop diarrhea of astringing the lung; Radix Curcumae regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Semen Cuscutae nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination; Concha Ostreae (calcined) tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN; Thallus Laminariae (Thallus Eckloniae) hard masses softening and resolving, expectorant, diuretic; Radix Scrophulariae removing heat from blood YIN nourishing, eliminating fire and detoxication; Rhizoma Dioscoreae Bulbiferae removing toxic substances and promoting subsidence of swelling, dissipating phlegm and resolving masses, all medicines share, and collaborative performance effective active, plays invigorating spleen to remove dampness, YANG hyperactivity suppressing nourishing YIN, effects such as blood fat reducing of reducing phlegm altogether.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. hyperlipemia lowering fat to dredge vessels medicament, is characterized in that, is prepared from primarily of following bulk drugs, is weight portion: Radix Puerariae 10-20, Caulis et Folium Arachidis hypogaeae 6-9, Folium Nelumbinis 10-20, Rhizoma Arisaematis 5-10, Herba Erigerontis 6-12, Semen Raphani 8-14, Fructus Crataegi 9-16, Fructus Hordei Germinatus 10-15, Herba Artemisiae Scopariae 7-12, Folium Ginkgo 5-10, Herba Apii graveolentis 6-9, Radix Curcumae 10-15, Semen Cuscutae 15-20, Concha Ostreae (calcined) 8-10, Thallus Laminariae (Thallus Eckloniae) 6-9, Radix Scrophulariae 4-8, Rhizoma Dioscoreae Bulbiferae 5-9.

2. hyperlipemia lowering fat to dredge vessels medicament as claimed in claim 1, it is characterized in that, Radix Puerariae 12-18, Caulis et Folium Arachidis hypogaeae 7-8, Folium Nelumbinis 12-18, Rhizoma Arisaematis 6-9, Herba Erigerontis 8-10, Semen Raphani 10-12, Fructus Crataegi 11-14, Fructus Hordei Germinatus 11-14, Herba Artemisiae Scopariae 8-11, Folium Ginkgo 7-8, Herba Apii graveolentis 7-8, Radix Curcumae 11-14, Semen Cuscutae 16-19, Concha Ostreae (calcined) 8.5-9.5, Thallus Laminariae (Thallus Eckloniae) 7-8, Radix Scrophulariae 5-7, Rhizoma Dioscoreae Bulbiferae 6-8 is (preferred, Radix Puerariae 15, Caulis et Folium Arachidis hypogaeae 7.5, Folium Nelumbinis 15, Rhizoma Arisaematis 7.5, Herba Erigerontis 9, Semen Raphani 11, Fructus Crataegi 12.5, Fructus Hordei Germinatus 12.5, Herba Artemisiae Scopariae 9.5, Folium Ginkgo 7.5, Herba Apii graveolentis 7.5, Radix Curcumae 12.5, Semen Cuscutae 17.5, Concha Ostreae (calcined) 9, Thallus Laminariae (Thallus Eckloniae) 7.5, Radix Scrophulariae 6, Rhizoma Dioscoreae Bulbiferae 7).

3. the hyperlipemia lowering fat to dredge vessels medicament as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Radix Puerariae, Fructus Crataegi, Fructus Hordei Germinatus and Herba Apii graveolentis decontamination, clean, dry, pulverize, obtained medicated powder;

(4) by Concha Ostreae (calcined) decontamination, break into pieces, put into pot, after decocting with water 30 minutes, add Caulis et Folium Arachidis hypogaeae, Folium Nelumbinis, Rhizoma Arisaematis, Herba Artemisiae Scopariae, Folium Ginkgo, Radix Curcumae, Semen Cuscutae, Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae, Rhizoma Dioscoreae Bulbiferae and step (1) (2) made crude drug, after boiling, a turn little fire decocts 20-50 minute, and (preferred, 30-40 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 35 minutes), filter, collect filtrate;

(5) step (3) made medicated powder is joined in step (4) gained filtrate while hot, stir, obtain decoction.

4. the preparation method of hyperlipemia lowering fat to dredge vessels medicament decoction as claimed in claim 3, is characterized in that, step (4) amount of water is that doubly (preferred, amount of water is 7-8 times of whole crude drug quality to the 6-9 of whole crude drug quality; Be more preferably, amount of water is 7.5 times of whole crude drug quality).

5. the hyperlipemia lowering fat to dredge vessels medicament as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Caulis et Folium Arachidis hypogaeae and Folium Ginkgo, remove impurity, is placed in frying pan, fries and has burnt brown macules to surface, and spray vinegar, takes out, dry;

(4) by Radix Puerariae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Concha Ostreae (calcined), Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae decontamination, clean, dry, pulverize together with step (1) (2) (3) made crude drug, mix with sucrose, pulverize and sieve, obtain powder.

6. the preparation method of hyperlipemia lowering fat to dredge vessels medicament powder as claimed in claim 5, is characterized in that, step (4) was pulverized 120-200 mesh sieve and (preferably, pulverized 140-180 mesh sieve; Be more preferably, pulverized 160 mesh sieves).

7. the hyperlipemia lowering fat to dredge vessels medicament as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Caulis et Folium Arachidis hypogaeae and Folium Ginkgo, remove impurity, is placed in frying pan, fries and has burnt brown macules to surface, and spray vinegar, takes out, dry;

(4) by Radix Puerariae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Concha Ostreae (calcined), Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae decontamination, clean, dry, pulverize together with step (1) (2) (3) made crude drug, mixing, add starch slurry and Icing Sugar, make soft material, granulate, dry, granulate, incapsulates every 0.4g, obtains capsule.

8. the preparation method of hyperlipemia lowering fat to dredge vessels drug capsule as claimed in claim 7, is characterized in that, step (4) was granulated 12-16 mesh sieve (preferred, 14 mesh sieves of granulating).

9. the hyperlipemia lowering fat to dredge vessels medicament as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable granule, its preparation method is:

(1) get Semen Raphani decontamination, mix thoroughly with rice wine, put into tank, obturage, be placed in the pot added water, steam and blotted to wine, take out, dry;

(2) getting wheat bran to be sprinkled in the frying pan of heat, after being heated to smolder, by going the Herba Erigerontis of impurity to pour in pot, covering one deck wheat bran more above, when to simmer to lower floor's wheat bran be coke yellow, stir-fry 10 minutes, take out, sieve and remove wheat bran, dry in the air cool;

(3) by Concha Ostreae (calcined) decontamination, break into pieces, put into pot, add the soak by water of whole crude drug quality 7.5 times after 30 minutes, add Radix Puerariae, Caulis et Folium Arachidis hypogaeae, Folium Nelumbinis, Rhizoma Arisaematis, Fructus Crataegi, Fructus Hordei Germinatus, Herba Artemisiae Scopariae, Folium Ginkgo, Herba Apii graveolentis, Radix Curcumae, Semen Cuscutae, Thallus Laminariae (Thallus Eckloniae), Radix Scrophulariae, Rhizoma Dioscoreae Bulbiferae and step (1) (2) made crude drug, after boiling, turn little fire and decoct, filter, collect filtrate;

(4) heating of step (3) gained filtrate is boiled into clear paste, adds dextrin, drying under reduced pressure, pulverize, guiding humid medium, soft material processed, granulate, 70 DEG C of dryings, granulate, obtains granule.

10. the preparation method of hyperlipemia lowering fat to dredge vessels medicament granule as claimed in claim 9, is characterized in that, step (3) turn little fire decocts 20-50 minute, and (preferred, 30-40 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 35 minutes).