CN104587310B - Help digestion qi-regulating particle and preparation method thereof - Google Patents

Help digestion qi-regulating particle and preparation method thereof Download PDF

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CN104587310B
CN104587310B CN201410830350.0A CN201410830350A CN104587310B CN 104587310 B CN104587310 B CN 104587310B CN 201410830350 A CN201410830350 A CN 201410830350A CN 104587310 B CN104587310 B CN 104587310B
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parts
cattail pollen
agaric
hawthorn
weight
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CN104587310A (en
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雷良平
邓国卫
龚艳霞
刘婷
李武
邓志水
刘明慧
熊耀洲
姚本军
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HUNAN ZHONGHE PHARMACEUTICAL CO Ltd
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HUNAN ZHONGHE PHARMACEUTICAL CO Ltd
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Abstract

Being helped digestion qi-regulating particle and preparation method thereof the invention discloses one kind, the qi-regulating particle that helps digestion is counted in parts by weight, including:18~50 parts of agaric, 20~50 parts of hawthorn, 18~50 parts of malt and 8~25 parts of cattail pollen.The qi-regulating particle that helps digestion, and stomach are helped digestion, qi-regulating and blood, have the significant qi-regulating effect that helps digestion, and promote digestion, and improvement is surfeited and causes hyperlipemia and indigestion, the symptom such as auxiliary treatment and indigestion suitable for hyperlipidemia.

Description

Help digestion qi-regulating particle and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, helped digestion qi-regulating particle and preparation method thereof more particularly to one kind.
Background technology
As social economy develops rapidly, lifestyle change, surfeit and lack motion, cause indigestion and Serious threat the living safety of the people to hyperlipidemia.Indigestion brings great pain.Blood fat is Refer to the general name of cholesterol, triglycerides and the lipoid such as phosphatide in blood plasma etc., research finds that the average blood plasma courage of obese people is consolidated Alcohol and triglyceride levels are significantly higher than non-obese person of the same age.Except body mass index (BMI) and blood lipid level are in obvious positive Outside the Pass, the distribution of body fat is also in close relations with blood plasma lipoprotein level.In general, centric obesity person is easier to occur Hyperlipidemia.After the weight loss of overweight people, blood fat disorder can also recover normal, and dietary structure can directly affect blood lipid level Just.Blood plasma cholesterol level easily in by diet cholesterol intake influenceed, feeding substantial amounts of saturated fatty acid can also increase The synthesis of cholesterol.Current treatment indigestion and lipid-regulation medicine are mainly chemical drugs, and it is big individual difference to be present, act on target Point is single, and tool side effect is big, the shortcomings of needing Long-term taking medicine and easily recur.So drug regimen of the exploitation with the qi-regulating that helps digestion has Very important meaning.
The content of the invention
Based on this, it is necessary to provide it is a kind of treat indigestion and auxiliary treating high blood fat disease help digestion qi-regulating particle and its Preparation method.
One kind helps digestion qi-regulating particle, counts in parts by weight, including:18~50 parts of agaric, 20~50 parts of hawthorn, 18~ 50 parts of malt and 8~25 parts of cattail pollen.
In one of the embodiments, count in parts by weight, in addition to:5~20 parts of sucrose and 10~40 parts of starch.
In one of the embodiments, count in parts by weight, including:18~40 parts of agaric, 20~40 parts of hawthorn, 25 ~50 parts of malt, 8~20 parts of cattail pollen, 5~13 parts of sucrose and 10~30 parts of starch.
In one of the embodiments, count in parts by weight, including:25~40 parts of agaric, 25~40 parts of hawthorn, 25 ~38 parts of malt, 14~20 parts of cattail pollen, 7~13 parts of sucrose and 20~30 parts of starch.
A kind of preparation method for the qi-regulating particle that helps digestion, comprises the following steps:
By 18~50 parts of agaric, 20~50 parts of hawthorn, 18~50 parts of malt and 8~25 parts cattail pollen crush and/ Or extracted with solvent, obtain the qi-regulating particle that helps digestion.
In one of the embodiments, comprise the following steps:
The agaric of above-mentioned parts by weight is crushed, obtains auricularia auriculajudae powder;
The malt of above-mentioned parts by weight is crushed, obtains malt flour;
The hawthorn of above-mentioned parts by weight is extracted with solvent, obtains hawthorn paste;
The cattail pollen of above-mentioned parts by weight is extracted with solvent, obtains cattail pollen cream;And
The auricularia auriculajudae powder, the malt flour, the hawthorn paste and the cattail pollen cream are mixed, obtain the qi-regulating that helps digestion Grain.
In one of the embodiments, the agaric of above-mentioned parts by weight is added in the cattail pollen, is extracted, obtained with solvent To filtrate and filter residue, the agaric is taken out from the filter residue, remaining filter residue continues solubilizer and extracted, merging filtrate, Cattail pollen cream is concentrated to give, the cattail pollen cream, the agaric, the malt of above-mentioned parts by weight and hawthorn are mixed, obtains described help digestion Qi-regulating particle.
In one of the embodiments, comprise the following steps:
By the agaric of above-mentioned parts by weight, hawthorn, malt and cattail pollen, extracted with solvent, obtain filtrate, the filtrate is dense Contracting, obtain the qi-regulating particle that helps digestion.
In one of the embodiments, comprise the following steps:By 18~50 parts of agaric, 20~50 parts of hawthorn, 18~ 50 parts of malt and 8~25 parts of cattail pollen are crushed and/or are extracted to obtain extract solution with solvent, and 5 are added to the extract solution ~20 parts of sucrose and 10~40 parts of starch, are mixed and softwood processed, are pelletized, and are dried, and obtain the qi-regulating particle that helps digestion.
The present invention qi-regulating particle that helps digestion is based on theory of traditional Chinese medical science, with reference to clinical practice, is sieved from traditional Chinese medicine material treasure-house That selects is a series of with stomach strengthening and digestion promoting, strengthening the spleen and replenishing qi, regulating qi-flowing for relieving pain, the Chinese medicine for helping digest effect.Wherein, agaric taste It is sweet, it is mild-natured, energy QI invigorating salubrity, hypoferric anemia can be prevented and treated, stomach can be dredged, lubricates enteron aisle, while to hyperpietic There is certain help;Hawthorn is the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting;Malt is sweet mild-natured, returns spleen, stomach, has The effect of strengthening the spleen and stomach, dispersing stagnated hepatoqi, promoting the circulation of qi helps digestion, for diseases such as dyspepsia, abdominal distention, spleen eating less;Cattail pollen has Hemostasis, stagnation resolvation, treating stranguria and other effects.The present invention help digestion qi-regulating particle drug component through dialectical compatibility, complemented each other using, With synergy, the effect of playing strengthening the spleen and stomach, dispersing stagnated hepatoqi, promoting digestion, cold dispelling eliminating dampness altogether, and stomach help digestion, qi-regulating and blood, With the significant qi-regulating effect that helps digestion, promote digestion, improvement is surfeited and causes hyperlipemia and indigestion, suitable for height The symptoms such as the auxiliary treatment and indigestion of pionemia.
Embodiment
For the ease of understanding the present invention, the present invention is described more fully below, and gives the preferable of the present invention Embodiment.But the present invention can realize in many different forms, however it is not limited to embodiment described herein.Phase Instead, there is provided the purpose of these embodiments is to make the understanding more thorough and comprehensive to the disclosure.
Unless otherwise defined, all of technologies and scientific terms used here by the article is with belonging to technical field of the invention The implication that technical staff is generally understood that is identical.Term used in the description of the invention herein is intended merely to description tool The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term as used herein " and/or " include one or more phases The arbitrary and all combination of the Listed Items of pass.
One kind helps digestion qi-regulating particle, counts in parts by weight, including:18~50 parts of agaric, 20~50 parts of hawthorn, 18~ 50 parts of malt and 8~25 parts of cattail pollen.
Particularly, help digestion qi-regulating particle, counts in parts by weight, in addition to:5~20 parts of sucrose and 10~40 parts of shallow lake Powder.
Preferably, help digestion qi-regulating particle, counts in parts by weight, including:18~40 parts of agaric, 20~40 parts of hawthorn, 25~50 parts of malt, 8~20 parts of cattail pollen, 5~13 parts of sucrose and 10~30 parts of starch.
It is highly preferred that the qi-regulating particle that helps digestion is counted in parts by weight, including:25~40 parts of agaric, 25~40 parts of hawthorn, 25~38 parts of malt, 14~20 parts of cattail pollen, 7~13 parts of sucrose and 20~30 parts of starch.
The present invention qi-regulating particle that helps digestion is based on theory of traditional Chinese medical science, with reference to clinical practice, is sieved from traditional Chinese medicine material treasure-house That selects is a series of with stomach strengthening and digestion promoting, strengthening the spleen and replenishing qi, regulating qi-flowing for relieving pain, the Chinese medicine for helping digest effect.
Wherein, agaric is sweet, mild-natured, energy QI invigorating salubrity, can prevent and treat hypoferric anemia, can dredge stomach, lubricate enteron aisle, Also there is certain help to hyperpietic simultaneously.
Hawthorn is the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting.
Malt is sweet mild-natured, returns spleen, stomach, has the effect of strengthening the spleen and stomach, dispersing stagnated hepatoqi, promoting the circulation of qi helps digestion, for dyspepsia Do not disappear, the disease such as abdominal distention, spleen eating less.
Cattail pollen, which has, stops blooding, stagnation resolvation, treating stranguria and other effects.
The present invention help digestion qi-regulating particle drug component through dialectical compatibility, complemented each other using, there is synergy, The effect of playing strengthening the spleen and stomach, dispersing stagnated hepatoqi, promoting digestion, cold dispelling eliminating dampness altogether, and stomach help digestion, qi-regulating and blood, have and significantly disappear Qi-regulating effect is eaten, promotes digestion, improvement is surfeited and causes hyperlipemia and indigestion, suitable for the auxiliary of hyperlipidemia The symptom such as treatment and indigestion.
The preparation method of the above-mentioned qi-regulating particle that helps digestion of one embodiment, comprises the following steps:
Step S1:The malt of above-mentioned parts by weight is crushed, obtains malt flour.
Especially, malt was crushed to 80 mesh sieves.
Step S2:The hawthorn of above-mentioned parts by weight is extracted with solvent, is concentrated to give hawthorn paste.
Especially, the proportion for being concentrated into hawthorn paste at 80~90 DEG C is 1.25~1.3.
Preferably, solvent is water, and the method for extraction is water boiling and extraction method.Preferably, step by step arithmetic twice is taken in extraction, The filter residue that is filtrated to get carries out second and extracted after extracting for the first time, the liquid that is filtrated to get after extracting for the first time and carries for the second time The liquid obtained after taking is concentrated after merging.Extract for the first time:The amount for adding water is 5~10 times of hawthorn parts by weight, is extracted Time clocked since boiling water, be 0.5~5 hour.Preferably, the amount for adding water is 8 times of hawthorn parts by weight, extraction Time clocks since boiling water, is 2 hours.Second of extraction:The amount for adding water is 4~8 times of hawthorn parts by weight, extraction Time clocks since boiling water, is 0.5~3 hour.Preferably, the amount for adding water is 6 times of hawthorn parts by weight, extraction when Between clocked since boiling water, be 1 hour.It is appreciated that second of extraction can omit, directly first time extraction is obtained Filtrate concentrates, and obtains hawthorn paste.
Step S3:The agaric of above-mentioned parts by weight is added in cattail pollen, is extracted with solvent, obtains filtrate and filter residue, will Agaric is taken out from filter residue, and remaining filter residue continues solubilizer and extracted, and merging filtrate, is concentrated to give cattail pollen cream.
Especially, the proportion for being concentrated into cattail pollen cream at 80~90 DEG C is 1.30~1.35.
Especially, cattail pollen or agaric are encased with cloth.Especially, the cattail pollen cream includes the extract of agaric and cattail pollen.
Solvent is selected from least one of water and ethanol.The method of extraction is water boiling and extraction method, alcohol dipping extraction method Or ethanol percolation extraction method.
Preferably, the agaric of above-mentioned parts by weight is added in cattail pollen, the method extracted with solvent is water boiling and extraction Method.The amount for adding water is 5~10 times of agaric and cattail pollen parts by weight, and the time of extraction clocks since boiling water, is 0.5~4 Hour.Preferably, the amount for adding water is 8 times of agaric and cattail pollen parts by weight, and the time of extraction clocks since boiling water, is 1.5 hour.
Preferably, the method remaining filter residue continuation solubilizer extracted is water boiling and extraction method, and is taken twice Step by step arithmetic.Extract for the first time:The amount for adding water is 3~10 times of cattail pollen parts by weight, and the time of extraction is remembered since boiling water When, it is 0.5~4 hour.Preferably, the amount for adding water is 7 times of cattail pollen parts by weight, and the time of extraction is remembered since boiling water When, it is 1 hour.Second of extraction:The amount for adding water is 4~8 times of cattail pollen parts by weight, and the time of extraction is remembered since boiling water When, it is 0.5~4 hour.Preferably, the amount for adding water is 6 times of cattail pollen parts by weight, and the time of extraction is remembered since boiling water When, it is 1 hour.It is appreciated that second of extraction step can omit, first time extraction is directly carried out, is concentrated to give cattail pollen cream.
S4:The agaric taken out in step S3 from filter residue is crushed to obtain auricularia auriculajudae powder.
Especially, agaric was crushed to 80 mesh sieves.
S5:Auricularia auriculajudae powder, malt flour, hawthorn paste and cattail pollen cream are mixed.
S6:After auricularia auriculajudae powder, malt flour, hawthorn paste and cattail pollen cream are mixed, add 5~20 parts sucrose and 10~40 parts Starch, is mixed and softwood processed, is pelletized, and is dried, is obtained the qi-regulating particle that helps digestion.
It is appreciated that step S1 can be omitted, malt is obtained into extract solution with solvent extraction, extract solution is subjected to step S5. Step S2 can be omitted, and hawthorn is crushed or extracted with solvent after obtaining extract solution, carry out step S5.Step S3 can be saved Slightly, cattail pollen is crushed or extracted with solvent after obtaining extract solution, carry out step S5.Step S3 can be omitted, by agaric Directly crushed after obtaining auricularia auriculajudae powder or being extracted with solvent, carry out step S5.Step S6 can be omitted, directly by agaric Powder, malt flour, hawthorn paste and cattail pollen cream are uniformly mixed so as to obtain the qi-regulating particle that helps digestion.
It is appreciated that above-mentioned preparation method can not be used, agaric, malt, hawthorn and cattail pollen are crushed, obtain the qi-regulating that helps digestion Particle;Or extract agaric, malt, hawthorn and cattail pollen, filtrate is obtained, filtrate is concentrated to give to the qi-regulating particle that helps digestion.
The preparation method of the above-mentioned qi-regulating particle that helps digestion, it is simple and convenient, the active ingredient of raw material is taken full advantage of, to greatest extent Ground make use of raw material, obtained to help digestion qi-regulating particle and stomach helps digestion, and qi-regulating and blood, has the significant qi-regulating effect that helps digestion, promotes Digestion, improvement are surfeited and cause hyperlipemia and indigestion, and the auxiliary treatment and digestion suitable for hyperlipidemia are not The symptom such as good.
It is specific embodiment below.
Embodiment 1
The present embodiment one kind helps digestion qi-regulating particle, counts in parts by weight, including:30 parts of agaric, 25 parts of hawthorn, malt 38 25 parts of part, 20 parts of cattail pollen, 10 parts of sucrose and starch.
The preparation method of the above-mentioned qi-regulating particle that helps digestion, comprises the following steps:
Malt be crushed into 80 mesh sieves and obtain malt flour, hawthorn is extracted with water, take step by step arithmetic twice, first Secondary extraction adds the water of 8 times of amounts of hawthorn quality, is heated to seething with excitement, and decocts 2h, filtering;Second of extraction adds 6 times of hawthorn quality The water of amount, it is heated to seething with excitement, decocts 1h, filtering, merging filtrate, be concentrated to give hawthorn paste.Cattail pollen is encased with cloth, agaric adds Into cattail pollen, extracted with water, add the water of 8 times of amounts of agaric and cattail pollen quality, be heated to seething with excitement, decocted 1.5h, filtration, obtain To filter residue, agaric is obtained into auricularia auriculajudae powder from filter residue taking-up is broken, remaining filter residue continues plus water is extracted, and takes and carries step by step twice Take, extraction for the first time adds the water of 7 times of amounts of cattail pollen quality, is heated to seething with excitement, and decocts 1h, filtering, and second of extraction adds cattail pollen The water of 6 times of quality amount, are heated to seething with excitement, and decoct 1h, filtering, merging filtrate, are concentrated to give cattail pollen cream, cattail pollen cream include agaric and The extract of cattail pollen.Auricularia auriculajudae powder, malt flour, sugarcane sugar and starch are mixed again, hawthorn paste is added and cattail pollen cream mixes, pelletize, do It is dry, obtain the qi-regulating particle that helps digestion.
Embodiment 2
The present embodiment one kind helps digestion qi-regulating particle, counts in parts by weight, including:18 parts of agaric, 30 parts of hawthorn, malt 25 20 parts of part, 14 parts of cattail pollen, 13 parts of sucrose and starch.
The preparation method of the above-mentioned qi-regulating particle that helps digestion, comprises the following steps:
Malt be crushed into 80 mesh sieves and obtain malt flour, hawthorn is extracted with water, take step by step arithmetic twice, first Secondary extraction adds the water of 10 times of amounts of hawthorn quality, is heated to seething with excitement, and decocts 0.5h, filtering;Second of extraction adds hawthorn quality 8 The water of amount again, is heated to seething with excitement, and decocts 3h, filtering, merging filtrate, is concentrated to give hawthorn paste.Cattail pollen is encased with cloth, agaric adds Enter into cattail pollen, extracted with water, add the water of 5 times of amounts of agaric and cattail pollen quality, be heated to seething with excitement, decoct 4h, filtration, obtain To filter residue, agaric is obtained into auricularia auriculajudae powder from filter residue taking-up is broken, remaining filter residue continues plus water is extracted, and takes and carries step by step twice Take, extraction for the first time adds the water of 10 times of amounts of cattail pollen quality, is heated to seething with excitement, and decocts 0.5h, filtering, and second of extraction adds Pu The water of yellow 4 times of amounts of quality, is heated to seething with excitement, and decocts 4h, filtering, and merging filtrate is concentrated to give cattail pollen cream, and cattail pollen cream includes agaric With the extract of cattail pollen.Auricularia auriculajudae powder, malt flour, sugarcane sugar and starch are mixed again, hawthorn paste is added and cattail pollen cream mixes, granulation, Dry, obtain the qi-regulating particle that helps digestion.
Embodiment 3
The present embodiment one kind helps digestion qi-regulating particle, counts in parts by weight, including:25 parts of agaric, 50 parts of hawthorn, malt 30 30 parts of part, 18 parts of cattail pollen, 7 parts of sucrose and starch.
The preparation method of the above-mentioned qi-regulating particle that helps digestion, comprises the following steps:
Malt is crushed to obtain malt flour, hawthorn is extracted with water, takes step by step arithmetic twice, extraction for the first time adds Enter the water of 5 times of amounts of hawthorn quality, be heated to seething with excitement, decoct 5h, filtering;Second of extraction adds the water of 4 times of amounts of hawthorn quality, adds Heat decocts 0.5h, filtering, merging filtrate, is concentrated to give hawthorn paste to seething with excitement.Cattail pollen is encased with cloth, agaric is added to cattail pollen In, extracted with water, add the water of 10 times of amounts of agaric and cattail pollen quality, be heated to seething with excitement, decocted 0.5h, filtration, filtered Slag, agaric being obtained into auricularia auriculajudae powder from filter residue taking-up is broken, remaining filter residue continues plus water is extracted, and takes step by step arithmetic twice, Extraction adds the water of 3 times of amounts of cattail pollen quality for the first time, is heated to seething with excitement, and decocts 4h, filtering, and second of extraction adds cattail pollen quality The water of 8 times of amounts, is heated to seething with excitement, and decocts 0.5h, filtering, and merging filtrate is concentrated to give cattail pollen cream, and cattail pollen cream includes agaric and Pu Yellow extract.Auricularia auriculajudae powder, malt flour, sugarcane sugar and starch are mixed again, hawthorn paste is added and cattail pollen cream mixes, pelletize, dry, Obtain the qi-regulating particle that helps digestion.
Embodiment 4
The present embodiment one kind helps digestion qi-regulating particle, counts in parts by weight, including:40 parts of agaric, 20 parts of hawthorn, malt 50 10 parts of part, 20 parts of cattail pollen, 5 parts of sucrose and starch.
The preparation method of the above-mentioned qi-regulating particle that helps digestion, comprises the following steps:
Agaric, hawthorn, malt and cattail pollen are merged, ethanol is added and carries out diacolation, ethanol and agaric, hawthorn, the wheat of addition Bud and cattail pollen cumulative volume ratio are 7:3.Filtrate is collected, when filtrate is without color, stops diacolation, filtrate is concentrated to give concentrate, Add sugarcane sugar and starch to mix, pelletize, dry, obtain the qi-regulating particle that helps digestion.
Embodiment 5
The present embodiment one kind helps digestion qi-regulating particle, counts in parts by weight, including:50 parts of agaric, 40 parts of hawthorn, malt 18 40 parts of part, 25 parts of cattail pollen, 20 parts of sucrose and starch.
The preparation method of the above-mentioned qi-regulating particle that helps digestion, comprises the following steps:
Agaric, hawthorn, malt and cattail pollen are merged, ethanol is added and carries out diacolation, ethanol and agaric, hawthorn, the wheat of addition Bud and cattail pollen cumulative volume ratio are 8:2.Filtrate is collected, when filtrate is without color, stops diacolation, filtrate is concentrated to give concentrate, Add sugarcane sugar and starch to mix, pelletize, dry, obtain the qi-regulating particle that helps digestion.
1) zoopery
First, experiment purpose
By taking embodiment 1 as an example, the qi-regulating Granules on Mouse that helps digestion for inquiring into auxiliary treating high blood fat disease of the present invention helps digestion qi-regulating Influence.
2nd, experimental method and experimental result
Kunming mouse 40, male and female half and half, 20~25g of body weight, fasting 12h, free water before experiment.It is randomly divided into 4 Group, every group 10.This experiment is divided into experimental group and control group, wherein, experimental group is divided into low dose group 0.5g/kg, middle dose group 1g/kg, tri- groups of high dose group 2g/kg.Control group is normally fed.Experimental group successive administration 10 days, one time a day, after last dose Fasting 16h (can't help water), and every mouse stomach gives dislocation execution mouse in place's after 0.1% methyl orange solution 0.2mL, 30min, rapidly Abdomen is opened, stomach is won and is placed in beaker, 10ml water is added, cuts off coat of the stomach, stomach is fully washed in water, uses sodium bicarbonate solution PH value is adjusted to 6~6.5, centrifuge tube is poured into, 4min is centrifuged with 5000r/min, supernatant is poured out, with spectrophotometer in wavelength The absorbance of solution is determined under 420nm, as remaining methyl orange amount in stomach, is averaged.Methyl orange Stomach residue rate (%)=stomach Methyl orange absorbance/radix methyl orange absorbance × 100% (after shaking up survey by 0.1% methyl orange 0.2mL additions 10mL distilled water Its absorbance is measured as radix methyl orange absorbance).
Experimental result is shown in Table 1:
Table 1
The result of table 1 shows:The qi-regulating particle that helps digestion of the present invention substantially reduces methyl orange residual rate in experimental mice stomach, Illustrate that the qi-regulating particle that helps digestion of the present invention effectively facilitates gastric emptying, the effect of serving reinforcing spleen to promote digestion.As can be seen here, the auxiliary Treatment hyperlipidemia help digestion qi-regulating particle and stomach helps digestion, qi-regulating and blood, can promote to digest, so as to play the high fat of auxiliary treatment The effect of mass formed by blood stasis.
2) clinical data
First, case source and therapeutic scheme
72 are diagnosed as dyspeptic sufferer from hospital outpatient with inpatient department.Wherein male 36, women 36. Age was at 18~60 years old.Dyspeptic primary symptom is:Epigastric discomfort or pain, glutted, sour regurgitation, belch, nausea and vomiting.Root It is grouped according to the cardinal symptom of sufferer, is divided into tetra- groups of A, B, C, D, every group 18, and to the symptom and parameters for observation on effect of sufferer Take symptom integral value, symptom integral value takes level Four point system, it is point light, in, again, seriously, remember 1,2,3,4 point respectively.Wherein, A cardinal symptom is epigastric discomfort, glutted, poor appetite;B cardinal symptom be epigastric discomfort, belch, poor appetite, Nausea;C cardinal symptom is upper abdomen pain, sour regurgitation, vomiting;D cardinal symptom is upper abdomen pain, sour regurgitation, the difficult peace of sleeping and eating. 72 sufferers are observation case, do not set contrast groups, and the present invention is only taken during observation has the reason that helps digestion of the qi-regulating effect that helps digestion Aerated particle medicine, each 6g, 3 times a day.Continuously take 30 days, strictly control other variable factors.Statistical result.
2nd, curative effect judging standard and experimental result
Cure:Symptom integral value declines more than 91%;It is effective:Symptom integral value declines 71%~90%;Effectively:Symptom is accumulated Score value declines 35%~70%;It is invalid:Symptom integral value declines less than 35%.Total effective rate for (cure number of cases+effective number of cases+ Effective number of cases)/total number of cases.
Experimental result is shown in Table 1:
Table 1
As can be known from the results of Table 1, dyspeptic sufferer is diagnosed as to help digestion qi-regulating particle 30 in the continuous present invention that takes After it, total effective rate has reached 88.9%.The present invention helps digestion qi-regulating particle and stomach helps digestion, qi-regulating and blood, has and significantly helps digestion Qi-regulating effect, suitable for epigastric discomfort caused by indigestion or the disease such as pain, glutted, sour regurgitation, belch, nausea and vomiting Shape.
3rd, safety observations
During medication is observed, sufferer blood, urine, stool routine and liver function no abnormality seen change, and find no the secondary work of any poison With with adverse reaction.
Embodiment described above only expresses the several embodiments of the present invention, and its description is more specific and detailed, but simultaneously Therefore the limitation to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that for one of ordinary skill in the art For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention Protect scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (2)

  1. A kind of 1. preparation method for the qi-regulating particle that helps digestion, it is characterised in that count in parts by weight, prepared by following active ingredient and Into:18~50 parts of agaric, 20~50 parts of hawthorn, 18~50 parts of malt and 8~25 parts of cattail pollen;The preparation method bag Include following steps:
    The malt of above-mentioned parts by weight is crushed, obtains malt flour;
    The hawthorn of above-mentioned parts by weight is extracted with solvent, obtains hawthorn paste;
    The agaric of above-mentioned parts by weight is added in the cattail pollen of above-mentioned parts by weight, extracted with water boiling and extraction method, added The amount of water is 5~10 times of agaric and cattail pollen parts by weight, and the time of extraction clocks since boiling water, is 0.5~4 hour, obtains To filtrate and filter residue;The agaric slag in the filter residue is taken out again and crushes to obtain auricularia auriculajudae powder, remaining filter residue continues solubilizer Extracted, merging filtrate, be concentrated to give cattail pollen cream, the cattail pollen cream includes the extract of agaric and cattail pollen;And
    The auricularia auriculajudae powder, the malt flour, the hawthorn paste and the cattail pollen cream are mixed, obtain the qi-regulating particle that helps digestion.
  2. 2. the preparation method of the qi-regulating particle according to claim 1 that helps digestion, it is characterised in that described by the agaric It is further comprising the steps of after the step of powder, the malt flour, the hawthorn paste and the cattail pollen cream mix:Add 5~20 parts Sucrose and 10~40 parts of starch, mix and softwood processed, pelletize, dry, obtain the qi-regulating particle that helps digestion.
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CN103719967A (en) * 2013-12-10 2014-04-16 马鞍山市安康菌业有限公司 Stomach-invigorating and digestion-helping energy drink and production method thereof
CN103749693A (en) * 2013-12-16 2014-04-30 马鞍山市安康菌业有限公司 Stomach-strengthening digestive functional beverage and preparation method thereof

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CN103719967A (en) * 2013-12-10 2014-04-16 马鞍山市安康菌业有限公司 Stomach-invigorating and digestion-helping energy drink and production method thereof
CN103749693A (en) * 2013-12-16 2014-04-30 马鞍山市安康菌业有限公司 Stomach-strengthening digestive functional beverage and preparation method thereof

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