CN104587188A - Formula of traditional Chinese medicine for treating premature ovarian failure - Google Patents
Formula of traditional Chinese medicine for treating premature ovarian failure Download PDFInfo
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- CN104587188A CN104587188A CN201510036359.9A CN201510036359A CN104587188A CN 104587188 A CN104587188 A CN 104587188A CN 201510036359 A CN201510036359 A CN 201510036359A CN 104587188 A CN104587188 A CN 104587188A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a formula of a traditional Chinese medicine for treating premature ovarian failure. The traditional Chinese medicine is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 2-3 parts of boschniakia rossica, 2-3 parts of lethariella zahlbruckneria, 1-3 parts of gorse, 1-2 parts of sparrow, 2-4 parts of licorice and lanatechead saussurea herb with flower, 3-5 parts of polyalthia root, 2-3 parts of Chinese date, 1-3 parts of panax japonicas, 2-3 parts of itea chinensis hook, 2-3 parts of pleurotus citrinopileatus sing, 3-5 parts of muraenesox cinereus, 2-3 parts of polygonatum kingianum, 3-5 parts of ventilago leiocarpa benth, 2-3 parts of cucubalus root and 5-8 parts of crocus sativus. The traditional Chinese medicine has the effects of invigorating spleen-stomach, replenishing qi, nourishing yin, promoting production of body fluid, nourishing liver and kidney by means of regulation of traditional Chinese medicinal materials, guarantees sufficient body fluid, can be used for improving the body immunity, and has a remarkable effect for treating premature ovarian failure.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine formula for the treatment of premature ovarian failure.
Background technology
Premature ovarian failure, refer to the women of built Regulations of Error Equation menstruation, before 40 years old, persistence amenorrhea and sexual organ's atrophy is there is due to ovarian failure, often there are the rising of Gonadotropin Level and estrogenic decline, before 40 years old, the sickness rate of premature ovarian failure is about 1% ~ 3%, and the sickness rate in 30 years old is about 0.1%.Clinical manifestation companion sees symptom before and after the menopause such as hectic fever hyperhidrosis in various degree, insomnia and dreamful sleep, irritable, cardiopalmus, tired, nervous, vaginal dryness, sexual disorder, sterility and infertility, amenorrhea in advance, make patient's geromorphism, if can not get adjusting timely and treating, the appearance of osteoporosis, cardiovascular and cerebrovascular disease chronic diseases can be caused, directly affect female life quality, have a strong impact on the normal work of women, bring considerable distress to its physical and mental health and love life simultaneously.
Premature ovarian failure, its cause of disease it be unclear that so far, so become focus and the difficult point of domestic and international reproductive development circle to the research of this disease.At present both at home and abroad research think more premature ovarian failure and hereditary, immune, metabolism and the factor such as iatrogenic relevant.Show chromosome mutation by research data; FSH (FSH) interstitialcellstimulating hormone (ICSH) (LH) and receptor variant thereof; Developmental and Metabolic Disorder or drug effect; chemicotherapy damages; viral infection; immunity and other high risk factors such as factor such as smoking, depression may be its reasons; these factors or make the congenital ovum decreased number of ovary; or its follicular atresia is accelerated; or directly destroyed; make follicle premature depletion, the treatment modern medicine for premature ovarian failure generally adopts hormone replacement therapy.
But premature ovarian failure treatment is more difficult, and doctor trained in Western medicine adopts Hormone Replacement Therapy clinically, needs to use estrogen and progestogen under the guidance of doctor.Time research shows this estrogen and progestogen therapy, have certain effect, can symptom be improved, but unsatisfactory to the recovery of ovarian function, and after drug withdrawal simultaneously, symptom reappears, and makes ovary be in dependent status, has and causes the worse possibility of ovarian function.That is Hormone Replacement Therapy only serves the effect taken stopgap measures, and this method side effect is large, and life-time service exogenous hormones has the danger causing endometrium canceration, and increases the sickness rate of coronary heart disease and cholecystopathy.Therefore the effect of this hormone therapy is undesirable, there is potential safety hazard simultaneously.In western medical treatment, except hormone replacement therapy, also there is induced ovulation, assist and give ovum technology, autologous or allosome ovary transplantation technology, immunosuppressant therapy, supplement calcium preparation or calcitonin treatment.But these western medical treatment methods are nothing more than recovery, maintenance, substitutes these several respects of ovarian function.Up to the present also do not have definite effective method can recover the function of ovary, so the premature ovarian failure cause of disease is complicated, treatment difficulty is comparatively large, and modern medicine not yet makes a breakthrough so far and carries out.
In recent years, along with Chinese medicine development, be more and more concerned with the chemotherapy that natural plant kind medicine substitutes in doctor trained in Western medicine.Chinese medicine has the integrally-regulated effect of multisystem too many levels, can improve ovarian function, improves ovarian reserve ability, and promote follicular development and ovulation, regulating menstruation and assisting pregnancy is antiabortive, is confirmed in long-term clinical practice.Current traditional Chinese medical herbal treatment primary disease, obtains certain curative effect, but this curative effect is not ideal, and effective percentage is low, is in particular in: 1. be all used as medicine with the former medicine complete feed of Chinese medicine at present, drug effect receives impact, and effect is undesirable; 2. prescription compatibility is unreasonable.Just because of these causes, cause existing treatment premature ovarian failure Chinese medicine clinical effectiveness desirable not to the utmost.
Summary of the invention
The invention provides a kind of Chinese medicine formula for the treatment of premature ovarian failure, according to tcm theory, nursed one's health by Chinese medicine, invigorating the spleen and replenishing QI, Yin-nourishing and body fluid promoting, nourishing the liver and kidney, body fluid is sufficient, improves immunity of organisms, and treatment premature ovarian failure has significant effect.
Medicine of the present invention is that crude drug prepares by the Chinese medicine of following parts by weight:
Herba Boschniakiae Rossicae 2-3 part, Alectoria virens Tayl. 2-3 part, Flos Caraganae Sinicae 1-3 part, passeris montani saturati 1-2 part, Radix Glycyrrhizae Herba Saussureae Involueratae 2-4 part, Polyalthia nemoralis A. D C. 3-5 part, Fructus Jujubae 2-3 part, Rhizoma Panacis Japonici 1-3 part, Yin Yalian 2-3 part, goldentop mushroom 2-3 part, Muraenesocis cinereus ovum 3-5 part, Rhizoma Polygonati 2-3 part, Radix seu Caulis Verntilaginis Leiocarpae 3-5 part, Radix Cucubali 2-3 part and Stigma Croci 5-8 part.
As preferably, prepare by following parts by weight:
Herba Boschniakiae Rossicae 3 parts, Alectoria virens Tayl. 2 parts, Flos Caraganae Sinicae 2 parts, passeris montani saturati 1 part, Radix Glycyrrhizae Herba Saussureae Involueratae 3 parts, Polyalthia nemoralis A. D C. 5 parts, 3 parts, Fructus Jujubae, Rhizoma Panacis Japonici 2 parts, Yin Yalian 3 parts, 3 parts, goldentop mushroom, 5 parts, Muraenesocis cinereus ovum, Rhizoma Polygonati 3 parts, Radix seu Caulis Verntilaginis Leiocarpae 4 parts, Radix Cucubali 2 parts and Stigma Croci 7 parts.
Chinese medicine of the present invention, prepare in the steps below:
Take raw material of Chinese medicine according to formula, Muraenesocis cinereus ovum grind into powder, all the other medical materials join in container, add water to cover powder and soak 10 ~ 20 minutes, then add water and no powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to seething with excitement, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges and adds the Muraenesocis cinereus ovum powder of grinding, eats together with Passeris montani saturati meat.
When taking, each 200 ~ 300ml, sooner or later respectively once, decoction being taken warmly after meal 14 days is a course for the treatment of.
Pharmacology analysis:
Herba Boschniakiae Rossicae: sweet, salty, temperature; Kidney invigorating and YANG supporting, loosening bowel to relieve constipation.For impotence due to deficiency of the kidney, chills and pain of the waist and kness, dryness of the intestine constipation.
Alectoria virens Tayl.: sweet, bitter is flat.Dispelling, collateral-activating, kidney invigorating and YANG supporting, regulating menstruation, hemostasis.For lumbago and skelalgia, hemiplegia, lumbago due to renal deficiency, sexual impotence, dizzy, menoxenia, leucorrhea; Wound hemorrhage is controlled in external.
Flos Caraganae Sinicae: sour, puckery, temperature.Kidney invigorating and YANG supporting, synthetism is stopped blooding.For impotence due to deficiency of the kidney; Wound hemorrhage is controlled in external, injury and bone fracture.
Passeris montani saturati: sweet in the mouth; Warm in nature.Sweet in the mouth; Warm in nature.Kidney invigorating and YANG supporting; Benefit essence is astringent or styptic treatment for spontaneous sweating.Main impotence due to deficiency of the kidney; Premature ejaculation; Seminal emission; Soreness of the waist and knees; Hernia; Frequent micturition; Metrorrhagia; Leukorrhagia; Pertussis; Carbuncle skin infection furuncle.
Sweet blue or green Herba Saussureae Involueratae: micro-hardship, heat.Poisonous.Strong muscle is active, and kidney invigorating and YANG supporting restores menstrual flow and invigorates blood circulation.For rheumatic arthritis, lumbago due to renal deficiency, sexual impotence, women's cold and pain in the lower abdomen, amenorrhea, placenta retention, lung cold cough, measles without adequate eruption.
Fructus Jujubae: sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.
Polyalthia nemoralis A. D C.: sweet is flat.Spleen reinforcing stomach invigorating, tonifying the kidney to consolidate the essence.Cure mainly chronic gastritis, inappetence, myasthenia of limbs, seminal emission.
Rhizoma Panacis Japonici: sweet, micro-hardship, temperature.Return liver, spleen, lung meridian.Strengthening by means of tonics, eliminating stasis to stop pain, hemostasis is eliminated the phlegm.For weak after being ill, chronic cough is spat blood, cough with copious phlegm, injury from falling down.
Yin Yalian: bitter, temperature.Expelling wind and removing dampness, strengthening by means of tonics, cough-relieving, removing toxic substances, detumescence.
Goldentop mushroom: sweet; Warm in nature.Spleen; Lung meridian.Strengthening by means of tonics; Main weakness is withered disease.
Muraenesocis cinereus ovum: strengthening by means of tonics.Main body void is frail; Liver cirrhosis; Fatty liver; Neurasthenia; Anemia.
Rhizoma Polygonati: sweet is flat.Return spleen, lung, kidney channel.Boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Radix seu Caulis Verntilaginis Leiocarpae: sweet, temperature.Benefiting vital QI and blood, dispelling, collateral-activating.Control deficiency of both QI and blood, rheumatalgia, traumatic injury.
Radix Cucubali: warm in nature, bitter in the mouth acid.Removing heat from blood, invigorates blood circulation, dampness removing, detumescence.Control women's amenorrhea, vicarious menstruation, traumatic injury, rheumatic arthritis, gonorrhea, edema, scrofula, swollen ulcer drug.
Stigma Croci: sweet in the mouth is flat, nontoxic.Enter the heart, Liver Channel.Blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens.Control troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, and spit blood, typhoid fever is gone mad, and frightened fear in a trance, women's amenorrhea, postnatal blood stasis is suffered from abdominal pain, tumbling and swelling.
Herba Boschniakiae Rossicae in formula of the present invention, Alectoria virens Tayl., Flos Caraganae Sinicae, Passeris montani saturati, sweet blue or green Herba Saussureae Involueratae are kidney-reinforcing drug, nourishing kidney; Fructus Jujubae, Polyalthia nemoralis A. D C., Rhizoma Panacis Japonici, Yin Yalian, goldentop mushroom, Muraenesocis cinereus ovum Yin-nourishing and body fluid promoting; Rhizoma Polygonati, Radix seu Caulis Verntilaginis Leiocarpae invigorating the spleen and replenishing QI; Radix Cucubali, Stigma Croci removing blood stasis stimulate the menstrual flow; All medicine compatibilities, treatment premature ovarian failure, treating both the principal and secondary aspects of a disease, has instant effect, eutherapeutic feature.
Clinical test results is as follows:
(1) inclusive criteria:
In April, 2014 to 2014, a year JIUYUE accepted 100 routine chain reaction in patients with premature ovarians for medical treatment, amenorrhea before clinical manifestation is 45 years old, the symptom of the menopausal syndromes such as each case appearance is infertile, sterile, mood change, paraesthesia, insomnia, hypomnesis, senile vaginitis, genital atrophy, dyspareunia, osteoporosis.Wherein 40 examples include this research range in.
(2), Outcome measure
Effective: above-mentioned symptom disappears, physical function recovers normal.
Take a turn for the better: above-mentioned symptom improves.
Invalid: above-mentioned symptom is without improvement.
(3), experiment conclusion
After treating 3-6 the course for the treatment of, in 40 routine clinical experiment patients, effective 17 people, take a turn for the better 12 people, invalid 11 people, total effective rate 72.5%.
Detailed description of the invention
Embodiment 1
Herba Boschniakiae Rossicae 3 parts, Alectoria virens Tayl. 2 parts, Flos Caraganae Sinicae 2 parts, passeris montani saturati 1 part, Radix Glycyrrhizae Herba Saussureae Involueratae 3 parts, Polyalthia nemoralis A. D C. 5 parts, 3 parts, Fructus Jujubae, Rhizoma Panacis Japonici 2 parts, Yin Yalian 3 parts, 3 parts, goldentop mushroom, 5 parts, Muraenesocis cinereus ovum, Rhizoma Polygonati 3 parts, Radix seu Caulis Verntilaginis Leiocarpae 4 parts, Radix Cucubali 2 parts and Stigma Croci 7 parts.
Chinese medicine formula of the present invention, prepare as follows and use:
Take raw material of Chinese medicine according to formula, Muraenesocis cinereus ovum grind into powder, all the other medical materials join in container, add water to cover powder and soak 15 minutes, then add water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 25 minutes to boiling, get filtrate; And then add water and do not have powder 5 centimetres, decoct with high heat and uses slow fire boiling again instead 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges and adds the Muraenesocis cinereus ovum powder of grinding, eats together with Passeris montani saturati meat.
When taking, each 250ml, sooner or later respectively once, decoction being taken warmly after meal.
Claims (2)
1. treat the Chinese medicine formula of premature ovarian failure, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Herba Boschniakiae Rossicae 2-3 part, Alectoria virens Tayl. 2-3 part, Flos Caraganae Sinicae 1-3 part, passeris montani saturati 1-2 part, Radix Glycyrrhizae Herba Saussureae Involueratae 2-4 part, Polyalthia nemoralis A. D C. 3-5 part, Fructus Jujubae 2-3 part, Rhizoma Panacis Japonici 1-3 part, Yin Yalian 2-3 part, goldentop mushroom 2-3 part, Muraenesocis cinereus ovum 3-5 part, Rhizoma Polygonati 2-3 part, Radix seu Caulis Verntilaginis Leiocarpae 3-5 part, Radix Cucubali 2-3 part and Stigma Croci 5-8 part.
2. the Chinese medicine formula for the treatment of premature ovarian failure according to claim 1, is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Herba Boschniakiae Rossicae 3 parts, Alectoria virens Tayl. 2 parts, Flos Caraganae Sinicae 2 parts, passeris montani saturati 1 part, Radix Glycyrrhizae Herba Saussureae Involueratae 3 parts, Polyalthia nemoralis A. D C. 5 parts, 3 parts, Fructus Jujubae, Rhizoma Panacis Japonici 2 parts, Yin Yalian 3 parts, 3 parts, goldentop mushroom, 5 parts, Muraenesocis cinereus ovum, Rhizoma Polygonati 3 parts, Radix seu Caulis Verntilaginis Leiocarpae 4 parts, Radix Cucubali 2 parts and Stigma Croci 7 parts.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497331A (en) * | 2015-12-25 | 2016-04-20 | 仵妍 | Traditional Chinese medicine formula for treating premature ovarian failure |
| CN105709112A (en) * | 2016-04-29 | 2016-06-29 | 张雪燕 | Pharmaceutical composition for preventing and treating premature ovarian failure as well as preparation method and application thereof |
| CN106334072A (en) * | 2016-10-31 | 2017-01-18 | 吴洁 | Traditional Chinese medicine for treating premature ovary failure and preparation method thereof |
| CN116369526A (en) * | 2023-06-06 | 2023-07-04 | 北京衡美金叶营养健康科技有限公司 | Composition for delaying body aging and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885960A (en) * | 2011-07-18 | 2013-01-23 | 天津太平洋制药有限公司 | Medicament for treating premature ovarian failure |
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- 2015-01-23 CN CN201510036359.9A patent/CN104587188A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885960A (en) * | 2011-07-18 | 2013-01-23 | 天津太平洋制药有限公司 | Medicament for treating premature ovarian failure |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497331A (en) * | 2015-12-25 | 2016-04-20 | 仵妍 | Traditional Chinese medicine formula for treating premature ovarian failure |
| CN105709112A (en) * | 2016-04-29 | 2016-06-29 | 张雪燕 | Pharmaceutical composition for preventing and treating premature ovarian failure as well as preparation method and application thereof |
| CN106334072A (en) * | 2016-10-31 | 2017-01-18 | 吴洁 | Traditional Chinese medicine for treating premature ovary failure and preparation method thereof |
| CN116369526A (en) * | 2023-06-06 | 2023-07-04 | 北京衡美金叶营养健康科技有限公司 | Composition for delaying body aging and preparation method and application thereof |
| CN116369526B (en) * | 2023-06-06 | 2023-09-01 | 北京衡美金叶营养健康科技有限公司 | Composition for delaying body aging and preparation method and application thereof |
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Application publication date: 20150506 |