CN104587189A - Traditional Chinese medicine formula for treating premature ovarian failure - Google Patents
Traditional Chinese medicine formula for treating premature ovarian failure Download PDFInfo
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- CN104587189A CN104587189A CN201510037152.3A CN201510037152A CN104587189A CN 104587189 A CN104587189 A CN 104587189A CN 201510037152 A CN201510037152 A CN 201510037152A CN 104587189 A CN104587189 A CN 104587189A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating premature ovarian failure. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 2-3 parts of boschniakia rossica, 2-3 parts of medical pipefish, 1-3 parts of cytisus, 2-3 parts of epimedium root, 2-4 parts of wallich pepper stem and leaf, 3-5 parts of japanese pyrola herb, 2-3 parts of jujube, 1-3 parts of polyalthia roots, 2-3 parts of sea cucumber, 1-3 parts of root of Yunnan sanicle, 1-3 parts of auricularia polytricha, 1-3 parts of polygonatum kingianum and 3-5 parts of ventilago leiocarpa benth. The traditional Chinese medicine has significant effects of strengthening the middle warmer, benefiting vital energy, nourishing yin, promoting the secretion of body fluid, nourishing the liver and kidneys, supplementing body fluid, improving the organism immunity and treating premature ovarian failure.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine formula for the treatment of premature ovarian failure.
Background technology
Premature ovarian failure, refer to the women of built Regulations of Error Equation menstruation, before 40 years old, persistence amenorrhea and sexual organ's atrophy is there is due to ovarian failure, often there are the rising of Gonadotropin Level and estrogenic decline, before 40 years old, the sickness rate of premature ovarian failure is about 1% ~ 3%, and the sickness rate in 30 years old is about 0.1%.Clinical manifestation companion sees symptom before and after the menopause such as hectic fever hyperhidrosis in various degree, insomnia and dreamful sleep, irritable, cardiopalmus, tired, nervous, vaginal dryness, sexual disorder, sterility and infertility, amenorrhea in advance, make patient's geromorphism, if can not get adjusting timely and treating, the appearance of osteoporosis, cardiovascular and cerebrovascular disease chronic diseases can be caused, directly affect female life quality, have a strong impact on the normal work of women, bring considerable distress to its physical and mental health and love life simultaneously.
Premature ovarian failure, its cause of disease it be unclear that so far, so become focus and the difficult point of domestic and international reproductive development circle to the research of this disease.At present both at home and abroad research think more premature ovarian failure and hereditary, immune, metabolism and the factor such as iatrogenic relevant.Show chromosome mutation by research data; FSH (FSH) interstitialcellstimulating hormone (ICSH) (LH) and receptor variant thereof; Developmental and Metabolic Disorder or drug effect; chemicotherapy damages; viral infection; immunity and other high risk factors such as factor such as smoking, depression may be its reasons; these factors or make the congenital ovum decreased number of ovary; or its follicular atresia is accelerated; or directly destroyed; make follicle premature depletion, the treatment modern medicine for premature ovarian failure generally adopts hormone replacement therapy.
But premature ovarian failure treatment is more difficult, and doctor trained in Western medicine adopts Hormone Replacement Therapy clinically, needs to use estrogen and progestogen under the guidance of doctor.Time research shows this estrogen and progestogen therapy, have certain effect, can symptom be improved, but unsatisfactory to the recovery of ovarian function, and after drug withdrawal simultaneously, symptom reappears, and makes ovary be in dependent status, has and causes the worse possibility of ovarian function.That is Hormone Replacement Therapy only serves the effect taken stopgap measures, and this method side effect is large, and life-time service exogenous hormones has the danger causing endometrium canceration, and increases the sickness rate of coronary heart disease and cholecystopathy.Therefore the effect of this hormone therapy is undesirable, there is potential safety hazard simultaneously.In western medical treatment, except hormone replacement therapy, also there is induced ovulation, assist and give ovum technology, autologous or allosome ovary transplantation technology, immunosuppressant therapy, supplement calcium preparation or calcitonin treatment.But these western medical treatment methods are nothing more than recovery, maintenance, substitutes these several respects of ovarian function.Up to the present also do not have definite effective method can recover the function of ovary, so the premature ovarian failure cause of disease is complicated, treatment difficulty is comparatively large, and modern medicine not yet makes a breakthrough so far and carries out.
In recent years, along with Chinese medicine development, be more and more concerned with the chemotherapy that natural plant kind medicine substitutes in doctor trained in Western medicine.Chinese medicine has the integrally-regulated effect of multisystem too many levels, can improve ovarian function, improves ovarian reserve ability, and promote follicular development and ovulation, regulating menstruation and assisting pregnancy is antiabortive, is confirmed in long-term clinical practice.Current traditional Chinese medical herbal treatment primary disease, obtains certain curative effect, but this curative effect is not ideal, and effective percentage is low, is in particular in: 1. be all used as medicine with the former medicine complete feed of Chinese medicine at present, drug effect receives impact, and effect is undesirable; 2. prescription compatibility is unreasonable.Just because of these causes, cause existing treatment premature ovarian failure Chinese medicine clinical effectiveness desirable not to the utmost.
Summary of the invention summary of the invention
The invention provides a kind of Chinese medicine formula for the treatment of premature ovarian failure, according to tcm theory, nursed one's health by Chinese medicine, invigorating the spleen and replenishing QI, Yin-nourishing and body fluid promoting, nourishing the liver and kidney, body fluid is sufficient, improves immunity of organisms, and treatment premature ovarian failure has significant effect.
Medicine of the present invention is that crude drug prepares by the Chinese medicine of following parts by weight:
Herba Boschniakiae Rossicae 2-3 part, Solenognathus 2-3 part, Flos Caraganae Sinicae 1-3 part, Rhizoma Epimedii 2-3 part, Caulis et Folium piperis 2-4 part, Herba pyrolae japonicae 3-5 part, Fructus Jujubae 2-3 part, Polyalthia nemoralis A. D C. 1-3 part, Stichopus japonicus 2-3 part, Radix Saniculae Astrantifoliae 1-3 part, Auricularia polytricha (Mout) Sacc. 1-3 part, Rhizoma Polygonati 1-3 part and Radix seu Caulis Verntilaginis Leiocarpae 3-5 part.
As preferably, prepare by following parts by weight:
Herba Boschniakiae Rossicae 3 parts, Solenognathus 2 parts, Flos Caraganae Sinicae 2 parts, Rhizoma Epimedii 3 parts, Caulis et Folium piperis 2 parts, Herba pyrolae japonicae 4 parts, 2 parts, Fructus Jujubae, Polyalthia nemoralis A. D C. 2 parts, Stichopus japonicus 2 parts, Radix Saniculae Astrantifoliae 3 parts, Auricularia polytricha (Mout) Sacc. 3 parts, Rhizoma Polygonati 3 parts and Radix seu Caulis Verntilaginis Leiocarpae 4 parts.
Chinese medicine of the present invention, prepare in the steps below:
Take raw material of Chinese medicine according to formula, Stichopus japonicus, Solenognathus grind into powder, all the other medical materials join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges and adds Stichopus japonicus and the Solenognathus powder of grinding.
When taking, each 200 ~ 300ml, sooner or later respectively once, decoction being taken warmly after meal 14 days is a course for the treatment of.
Pharmacology analysis:
Herba Boschniakiae Rossicae: sweet, salty, temperature; Kidney invigorating and YANG supporting, loosening bowel to relieve constipation.For impotence due to deficiency of the kidney, chills and pain of the waist and kness, dryness of the intestine constipation.
Solenognathus: sweet, temperature.Return liver, kidney channel.Warming the kidney to invigorate YANG, mass dissipating and swelling eliminating.For impotence and seminal emission, lump in the abdomen, scrofula sucutaneous nodule, injury from falling down; External treatment carbuncle furuncle.
Flos Caraganae Sinicae: sour, puckery, temperature.Kidney invigorating and YANG supporting, synthetism is stopped blooding.For impotence due to deficiency of the kidney; Wound hemorrhage is controlled in external, injury and bone fracture.
Rhizoma Epimedii: control empty pouring, nebulousurine, leucorrhea, menoxenia, children's's night blindness, carbuncle becomes pus not burst.
Caulis et Folium piperis: pungent, temperature.Wind-damp dispelling, the meridian dredging, strong waist foot, pain relieving.Control anemofrigid-damp arthralgia, bones and muscles pain, lumbago, postoperative pain." not Lu ": main incised wound pain." Kaibao Bencao ": main air blood, mend old and feeble, play sun, strong waist foot, eliminating impediment, bleaches, and by cold air, air draft is evil.Also liquor clothes, also infusing drugs in wine clothes, the eleventh month of the lunar calendar uses it.
Herba pyrolae japonicae: bitter is flat, nontoxic." Shaanxi Chinese medicinal herbal ": often make emmenagogue.For tea-drinking, for gynecological's deficiency of YIN, leucorrhea." Shaanxi medical herbs ": kidney invigorating and YANG supporting, astringing to arrest bleeding.Control cough due to consumptive disease, anemofrigid-damp arthralgia, hemiplegia. the foot and knee being feeble and various hemorrhage.
Fructus Jujubae: sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.
Polyalthia nemoralis A. D C.: sweet is flat.Spleen reinforcing stomach invigorating, tonifying the kidney to consolidate the essence.Cure mainly chronic gastritis, inappetence, myasthenia of limbs, seminal emission.
Stichopus japonicus: the kidney invigorating and essence nourishing, nourishes blood naughty dry.Control essence and blood loss, weak labor is timid, sexual impotence, nocturnal emission, frequent micturition, and dryness of the intestine is just difficult.
Radix Saniculae Astrantifoliae: sweet, micro-hardship, temperature.Invigorating the lung and the kidney.For pulmonary tuberculosis, lumbago due to renal deficiency, dizzy.
Auricularia polytricha (Mout) Sacc.: sweet is flat.Fill blood, lung moistening, hemostasis.For Qi and blood deficiency, extremity are twitched, cough due to deficiency of the lung, spitting of blood, spit blood, epistaxis, metrorrhagia, hypertension, constipation.
Rhizoma Polygonati: sweet is flat.Return spleen, lung, kidney channel.Boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Radix seu Caulis Verntilaginis Leiocarpae: sweet, temperature.Benefiting vital QI and blood, dispelling, collateral-activating.Control deficiency of both QI and blood, rheumatalgia, traumatic injury.
Herba Boschniakiae Rossicae in formula of the present invention, Solenognathus, Flos Caraganae Sinicae, Rhizoma Epimedii, Caulis et Folium piperis, Herba pyrolae japonicae are kidney-reinforcing drug, nourishing kidney; Fructus Jujubae, Polyalthia nemoralis A. D C., Stichopus japonicus, Radix Saniculae Astrantifoliae Yin-nourishing and body fluid promoting; Auricularia polytricha (Mout) Sacc., Rhizoma Polygonati, Radix seu Caulis Verntilaginis Leiocarpae invigorating the spleen and replenishing QI; All medicine compatibilities, treatment premature ovarian failure, treating both the principal and secondary aspects of a disease, has instant effect, eutherapeutic feature.
Clinical test results is as follows:
(1) inclusive criteria:
Year June in January, 2014 to 2014 accepts 100 routine chain reaction in patients with premature ovarians for medical treatment, amenorrhea before clinical manifestation is 45 years old, the symptom of the menopausal syndromes such as each case appearance is infertile, sterile, mood change, paraesthesia, insomnia, hypomnesis, senile vaginitis, genital atrophy, dyspareunia, osteoporosis.Wherein 40 examples include this research range in.
(2), Outcome measure
Effective: above-mentioned symptom disappears, physical function recovers normal.
Take a turn for the better: above-mentioned symptom improves.
Invalid: above-mentioned symptom is without improvement.
(3), experiment conclusion
After treating 3-6 the course for the treatment of, in 40 routine clinical experiment patients, effective 19 people, take a turn for the better 9 people, invalid 12 people, total effective rate 70%.
Detailed description of the invention
Embodiment 1
Herba Boschniakiae Rossicae 3 parts, Solenognathus 2 parts, Flos Caraganae Sinicae 2 parts, Rhizoma Epimedii 3 parts, Caulis et Folium piperis 2 parts, Herba pyrolae japonicae 4 parts, 2 parts, Fructus Jujubae, Polyalthia nemoralis A. D C. 2 parts, Stichopus japonicus 2 parts, Radix Saniculae Astrantifoliae 3 parts, Auricularia polytricha (Mout) Sacc. 3 parts, Rhizoma Polygonati 3 parts and Radix seu Caulis Verntilaginis Leiocarpae 4 parts.
Chinese medicine formula of the present invention, prepare as follows and use:
Take raw material of Chinese medicine according to formula, Stichopus japonicus, Solenognathus grind into powder, all the other medical materials join in container, add water to cover powder and soak 15 minutes, then add water and do not have powder 5 centimetres, decoct with high heat and use slow fire boiling again instead 25 minutes to boiling, get filtrate; And then add water and do not have powder 5 centimetres, decoct with high heat and uses slow fire boiling again instead 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges and adds Stichopus japonicus and the Solenognathus powder of grinding.
When taking, each 250ml, sooner or later respectively once, decoction being taken warmly after meal.
Claims (2)
1. treat a Chinese medicine formula for premature ovarian failure, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Herba Boschniakiae Rossicae 2-3 part, Solenognathus 2-3 part, Flos Caraganae Sinicae 1-3 part, Rhizoma Epimedii 2-3 part, Caulis et Folium piperis 2-4 part, Herba pyrolae japonicae 3-5 part, Fructus Jujubae 2-3 part, Polyalthia nemoralis A. D C. 1-3 part, Stichopus japonicus 2-3 part, Radix Saniculae Astrantifoliae 1-3 part, Auricularia polytricha (Mout) Sacc. 1-3 part, Rhizoma Polygonati 1-3 part and Radix seu Caulis Verntilaginis Leiocarpae 3-5 part.
2. the Chinese medicine formula for the treatment of premature ovarian failure according to claim 1, is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Herba Boschniakiae Rossicae 3 parts, Solenognathus 2 parts, Flos Caraganae Sinicae 2 parts, Rhizoma Epimedii 3 parts, Caulis et Folium piperis 2 parts, Herba pyrolae japonicae 4 parts, 2 parts, Fructus Jujubae, Polyalthia nemoralis A. D C. 2 parts, Stichopus japonicus 2 parts, Radix Saniculae Astrantifoliae 3 parts, Auricularia polytricha (Mout) Sacc. 3 parts, Rhizoma Polygonati 3 parts and Radix seu Caulis Verntilaginis Leiocarpae 4 parts.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105497331A (en) * | 2015-12-25 | 2016-04-20 | 仵妍 | Traditional Chinese medicine formula for treating premature ovarian failure |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102885960A (en) * | 2011-07-18 | 2013-01-23 | 天津太平洋制药有限公司 | Medicament for treating premature ovarian failure |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102885960A (en) * | 2011-07-18 | 2013-01-23 | 天津太平洋制药有限公司 | Medicament for treating premature ovarian failure |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497331A (en) * | 2015-12-25 | 2016-04-20 | 仵妍 | Traditional Chinese medicine formula for treating premature ovarian failure |
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Application publication date: 20150506 |
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