CN104547714B - Chinese traditional medicine for treating periodontitis and preparation method thereof - Google Patents

Chinese traditional medicine for treating periodontitis and preparation method thereof Download PDF

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CN104547714B
CN104547714B CN201510039472.2A CN201510039472A CN104547714B CN 104547714 B CN104547714 B CN 104547714B CN 201510039472 A CN201510039472 A CN 201510039472A CN 104547714 B CN104547714 B CN 104547714B
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herba
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CN104547714A (en
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荣宁
田春辉
荣风欣
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Jiangsu Huaxia Textile Industry Development Co ltd
Nantong Huaxia Shili Network Technology Service Co ltd
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating periodontitis and a preparation method of the traditional Chinese medicine preparation, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation comprises the following effective components: megalanthum, cicada slough, prismatomeris tetrandra, winter jasmine, clematis filamentosa, eupatorium, coconut pulp, ferula asafetida, abelmosk, aster panduratus, mongolian oak, mulberry, lophatherum gracile, cyathula prostrate, duckweed and capparis acutifolia. The traditional Chinese medicine preparation disclosed by the invention has the effects of clearing away heat and toxic materials, removing swelling and reliving pain, activating blood and removing stasis as well as stopping pain and closing sores, has a remarkable treatment effect on gomphiasis, gingival atrophy, redness and swelling of the gum, ozostomia, tartar and tartar accumulation caused by periodontitis, and symptoms such as toothache caused by sour, sweet, cold and hot food, and has the advantages that the effect can be taken into play rapidly, the treatment effect is remarkable, the diseases do not relapse after being healed, and the medicinal materials used in the traditional Chinese medicine preparation are easy to obtain, good in weather resistance, low in cost and free of toxic or side effect.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of periodontitis
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of periodontitis.
Background technology
Periodontitis is the chronic inflammatory disease invading gingiva and periodontal tissue, and be a kind of destructive disease, its principal character is the formation of periodontal pocket and the inflammation of bag wall, and frontal resorption and tooth loosen gradually, and it is the main cause causing adult's loss of tooth.
The main clinical manifestation of periodontitis is gingivitis, hemorrhage, periodontal pocket formation, frontal resorption, phatnoma bone height reduce, odontoseisis displacement, masticatory atonia, severe patient tooth can self falling or cause pulling out of tooth.Patients with periodontal disease gingiva color is dark red, because edema seems brighter, not only occurs gingival hemorrhage when brushing teeth, sometimes also hemorrhage when speaking or sting hard object, even also can have spontaneous hemorrhage; Early stage in inflammation, light visit gingival sulcus can be hemorrhage, visit to examine and hemorrhagely can be used as the important indicator that diagnosis gingiva has NIP, the formation of periodontal pocket illustrates that inflammation develops into Periodontal Supporting Tissue from gingiva, make to infect compared with the periodontal tissue of deep layer, chronic destruction, purulent secretion can overflow from periodontal pocket; Gingival recession is also one of symptom of periodontitis, but patient Chang Buyi discovers, and when gingiva retraction causes diseased Root Surfaces to expose, patient may occur responsive performance to hot and cold, sweet, sour food or mechanical irritation; Early stage periodontitis tooth does not loosen, only at chronic destructive inflammatory development to certain degree, alveolar bone major part absorb, when periodontal tissue's supporting strength greatly weakens, odontoseisis just can be caused even to come off.
At present, the drug main for the treatment of periodontitis will comprise some collutorys and gel-like periodontal pocket administration slow releasing preparation, and class of wherein gargling medicine cannot penetrate into periodontal pocket deep, and curative effect is poor; Gel-like slow releasing pharmaceutical determined curative effect in theory, but be limited by oral conditions in actual applications, curative effect is not undesirable, and the medicine for the treatment of periodontitis is more both at home and abroad, Western medicine is had also to have Chinese medicine, but, there is the shortcomings such as drug price is high, toxic and side effects is large, therapeutic effect is unsatisfactory.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of periodontitis; Chinese medicine preparation of the present invention has heat-clearing and toxic substances removing, reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, effect of analgesic therapy sore, the odontoseisis caused treatment periodontitis, gingival atrophy, red swelling of gingiva are hemorrhage, halitosis, tartar and tartar are piled up and meet sour, sweet, hot and cold food just the tooth symptom such as to ache there is significant curative effect; The medicinal raw material chosen is easy to get, and better tolerance is with low cost, without any side effects, and has effect rapidly, and therapeutic effect is obvious, the advantage of non-relapse after healing.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for periodontitis, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 57 ~ 87 portions of Periostracum Cicadaes 57 ~ 82 parts of xanthorrhizas 52 ~ 82 parts of Flos Jasmini Nudifloris 52 ~ 77 parts
Clematis filamentosa Dunn 47 ~ 77 portions of Herba Eupatoriis 42 ~ 72 parts of Sucus Cocoiss 42 ~ 72 parts of Resina Ferulaes 37 ~ 67 parts
27 ~ 52 parts, Radix seu folium abelmoschi moschati 37 ~ 67 parts of Aster panduratus Nees ex Walpers 32 ~ 62 parts of Cortex querci dentatae 27 ~ 57 portions of Fructus Moris
Herba Lophatheri 22 ~ 52 parts of Herba Cyathulae Prostratae 17 ~ 47 portions of Herba Spirodelaes 12 ~ 42 parts of Radix Capparis Membranaceaes 10 ~ 37 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 62 ~ 82 portions of Periostracum Cicadaes 62 ~ 77 parts of xanthorrhizas 57 ~ 77 parts of Flos Jasmini Nudifloris 57 ~ 72 parts
Clematis filamentosa Dunn 52 ~ 72 portions of Herba Eupatoriis 47 ~ 67 parts of Sucus Cocoiss 47 ~ 67 parts of Resina Ferulaes 42 ~ 62 parts
32 ~ 47 parts, Radix seu folium abelmoschi moschati 42 ~ 62 parts of Aster panduratus Nees ex Walpers 37 ~ 57 parts of Cortex querci dentatae 32 ~ 52 portions of Fructus Moris
Herba Lophatheri 27 ~ 47 parts of Herba Cyathulae Prostratae 22 ~ 42 portions of Herba Spirodelaes 17 ~ 37 parts of Radix Capparis Membranaceaes 15 ~ 32 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 67 ~ 77 portions of Periostracum Cicadaes 67 ~ 72 parts of xanthorrhizas 62 ~ 72 parts of Flos Jasmini Nudifloris 62 ~ 67 parts
Clematis filamentosa Dunn 57 ~ 67 portions of Herba Eupatoriis 52 ~ 62 parts of Sucus Cocoiss 52 ~ 62 parts of Resina Ferulaes 47 ~ 57 parts
37 ~ 42 parts, Radix seu folium abelmoschi moschati 47 ~ 57 parts of Aster panduratus Nees ex Walpers 42 ~ 52 parts of Cortex querci dentatae 37 ~ 47 portions of Fructus Moris
Herba Lophatheri 32 ~ 42 parts of Herba Cyathulae Prostratae 27 ~ 37 portions of Herba Spirodelaes 22 ~ 32 parts of Radix Capparis Membranaceaes 20 ~ 27 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 72 portions of Periostracum Cicadaes 69 parts of xanthorrhizas 67 parts of Flos Jasmini Nudifloris 65 parts
Clematis filamentosa Dunn 62 portions of Herba Eupatoriis 57 parts of Sucus Cocoiss 57 parts of Resina Ferulaes 52 parts
39 parts, Radix seu folium abelmoschi moschati 52 parts of Aster panduratus Nees ex Walpers 47 parts of Cortex querci dentatae 42 portions of Fructus Moris
Herba Lophatheri 37 parts of Herba Cyathulae Prostratae 32 portions of Herba Spirodelaes 27 parts of Radix Capparis Membranaceaes 24 parts.
State a preparation method for the Chinese medicine preparation for the treatment of periodontitis, comprise following processing step:
(1) Herba Clinopodii megalanthi, Periostracum Cicadae, Clematis filamentosa Dunn, Herba Eupatorii, Radix seu folium abelmoschi moschati, Aster panduratus Nees ex Walper, Herba Lophatheri, Herba Cyathulae Prostratae and Radix Capparis Membranaceae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.12 ~ 1.15, for subsequent use;
(2) xanthorrhiza and Fructus Mori are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 50% of 3 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.14, for subsequent use;
(3) Flos Jasmini Nudiflori and Resina Ferulae are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Sucus Cocois and Herba Spirodelae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) Cortex querci dentatae is put into dirt fire combustion, burn till Lycoperdon polymorphum Vitt, taking-up is ground into powder, crosses 200 order fine powders, for subsequent use.
(6) by thick paste, fine powder and the juice mix homogeneously obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the Chinese medicine preparation for the treatment of periodontitis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Clinopodii megalanthi: acrid in the mouth, micro-hardship, cold nature.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Cardinal teeth pain, rheumatalgia, skin ulcer swells, little and infantile malnutrition, treating swelling and pain by traumatic injury.
Periostracum Cicadae: sweet in the mouth, cold in nature; Return lung, Liver Channel.Loose wind heat extraction, sore-throat relieving rash, nebula removing spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus." detailed outline " carries: " control phlegm-accumulating vertigo, skin wind heat, varioliform exanthema is had an itch, tetanus and treatment toxic swelling skin ulcer, and adult's aphonia, children's's lockjaw sky hangs, frightened night cry of crying, swelling of the vulva.”
Xanthorrhiza: mildly bitter flavor, cool in nature.Cooling blood for hemostasis, dampness removing jaundice eliminating.For leukemia, aplastic anemia, gingival hemorrhage, hepatitis, urinary tract infection.Modern medicine study confirms, the xanthorrhiza preparation extracted with rare alcohol reflux, has height antibacterial action, have moderate antibacterial action to group B streptococcus, streptococcus pneumoniae, Bacillus typhi, diphtheria corynebacterium and shigella flexneri to staphylococcus aureus, anthrax bacillus.
Flos Jasmini Nudiflori: bitter in the mouth, micro-pungent, property is put down; Return kidney, urinary bladder channel.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Main fever and headache, laryngopharynx swelling and pain, urine burning pain, malignant boil toxic swelling, traumatic injury." Guizhou folk medicine " carries: " antipyretic diuresis.Control fever and headache, urine burning pain.”
Clematis filamentosa Dunn: bitter in the mouth, slightly cool in nature; GUIXIN, Liver Channel.Sedation and analgesia, clearing away liver-fire, mind calming god, blood pressure lowering, removing obstruction in the collateral to relieve pain.Main hypertension, insomnia, headache, numb limbs and tense tendons, wind-heat of liver channel, conjunctival congestion and swelling pain, acute toothache, rheumatic arthralgia.Modern medicine study confirms, Clematis filamentosa Dunn is to the symptom improved caused by hypertension, as headache, giddy, feeling of fullness in the head, numb limbs and tense tendons, insomnia etc. has good curative effect, and preliminary observation all has therapeutical effect to the hemiplegic patient caused patients with coronary heart disease and cerebrovas-cularaccident simultaneously.
Herba Eupatorii: acrid in the mouth, property is put down; Return spleen, stomach, lung meridian.Removing dampness by means of aromatics, appetizing of being amusing, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, heat-damp in summer table disease, feeling of fullness in the head is uncomfortable in chest.Modern medicine study confirms, Herba Eupatorii 100% water decoction tube dilution method, have inhibitory action to diphtheria corynebacterium, staphylococcus aureus, sarcina, Bacillus proteus, Bacillus typhi etc., its volatile oil infected by influenza also has inhibitory action.
Sucus Cocois: sweet in the mouth, cool in nature.Promote the production of body fluid, diuresis, hemostasis.Main xerostomia excessive thirst, edema, spits blood." Haiyao Bencao, Oversea Materia Medica " carries: " master quenches one's thirst, and spit blood, edema, goes wind heat.”
Resina Ferulae: bitter in the mouth, pungent, warm in nature; Return spleen, stomach warp.Change disease removing food stagnancy, parasite killing preventing the attack (or recurrence) of malaria.Cure mainly lump in the abdomen mass in the abdomen, malnutrition due to parasitic infestation, food stagnation, distension and fullness of the chest and abdomen, cold type of pain, malaria, dysentery.Modern medicine study confirms, the irritant phlegm-dispelling functions of Resina Ferulae, has inhibitory action to Bacillus tuberculosis.
Radix seu folium abelmoschi moschati: taste is micro-sweet, cold in nature; GUIXIN, lung meridian.Heat-clearing and toxic substances removing, stimulating milk secretion relieving constipation.Main hyperpyrexia, cough due to lung-heat, dysentery, constipation, puerperal, galactostasis, fractured, carbuncle skin ulcer abscess, and innominate toxic swelling and water inflammation are scalded." Guangxi Chinese herbal medicine " carries: " removing toxic substances and promoting subsidence of swelling, evacuation of pus pain relieving.Control carbuncle skin ulcer to swell and ache, innominate toxic swelling, carbuncle of the nape.”
Aster panduratus Nees ex Walper: bitter in the mouth, pungent, warm in nature.Warming the lung to relieve cough, dispersing cold for relieving pain.Main lung cold cough with asthma, stomachache with cool feeling." North Guangdong Chinese herbal medicine " carries: " promoting the circulation of QI to relieve pain, relieving cough and asthma.”
Cortex querci dentatae: bitter in the mouth, puckery, property is put down.Removing toxic substances and promoting subsidence of swelling, astringing intestine to stop diarrhea, hemostasis.Main sore, carbuncle and painful swelling, diabrosis is not held back, scrofula, hemorrhoid, dysentery, discharging fresh blood stool." detailed outline " carries: " only dysentery with red and white feces, discharging fresh blood stool.”
Fructus Mori: sweet in the mouth, acid, cold in nature; GUIXIN, liver, kidney channel.To enrich blood YIN nourishing, promote the production of body fluid and moisturize.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation." occupying diet spectrum with breath " carries: " wind-damp dispelling, walks with vigorous strides to carry out, breath wind syndrome caused by deficiency, clear asthenic fire for nourish liver and kidney, enrich blood.”
Herba Lophatheri: sweet in the mouth, light, cold in nature; GUIXIN, stomach, small intestine meridian.Clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue." modern Practical Chinese medicinal " carries: " refrigerant antipyretic, diuresis.Control calentura thirsty, difficulty and pain in micturition, dysphoria with smothery sensation is insomnia, gingival swelling and pain, stomatitis.”
Herba Cyathulae Prostratae: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis.Main carbuncle pyogenic infections from tumour or sore, venom, traumatic injury congestive edema." Chinese herbal medicine handbook is commonly used in Hainan Island " carries: " detumescence, pain relieving, pulls out bullet, except all poison.Control various venom, hepatosplenomegaly, bullet incarnation.”
Herba Spirodelae: acrid in the mouth, cold in nature; Return lung, urinary bladder channel.Relieving the exterior syndrome by diaphoresis, rash is antipruritic, inducing diuresis to remove edema, heat-clearing and toxic substances removing.Main air hotlist is demonstrate,proved, measles without adequate eruption, urticaria pruritus, edema, the difficulty in urination, skin ulcer tinea, erysipelas, scalds." detailed outline " carries: " the wet paralysis of main air, beriberi, beats and flutter damage, conjunctivitis, aphtha of the mouth and tongue, spits blood, epistaxis, paralysed wind, erysipelas.”
Radix Capparis Membranaceae: bitter in the mouth, puckery, property is put down, poisonous.Promoting blood circulation to remove blood stasis, relieving spasm to stop pain.For rheumatic arthritis, muscles and bones is not relaxed, laryngopharynx swelling and pain, toothache, and stomachache, amenorrhea, furuncle toxic swelling is controlled in external, traumatic injury.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention has heat-clearing and toxic substances removing, reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, effect of analgesic therapy sore, the odontoseisis caused treatment periodontitis, gingival atrophy, red swelling of gingiva are hemorrhage, halitosis, tartar and tartar are piled up and meet sour, sweet, hot and cold food just the tooth symptom such as to ache there is significant curative effect.
2, the medicinal raw material that Chinese medicine preparation of the present invention is chosen is easy to get, and better tolerance is with low cost, without any side effects, and has effect rapidly, and therapeutic effect is obvious, the advantage of non-relapse after healing.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Clinopodii megalanthi 82g Periostracum Cicadae 77g xanthorrhiza 77g Flos Jasmini Nudiflori 72g
Clematis filamentosa Dunn 72g Herba Eupatorii 67g Sucus Cocois 67g Resina Ferulae 62g
Radix seu folium abelmoschi moschati 62g Aster panduratus Nees ex Walper 57g Cortex querci dentatae 52g Fructus Mori 47g
Herba Lophatheri 47g Herba Cyathulae Prostratae 42g Herba Spirodelae 37g Radix Capparis Membranaceae 32g.
Treat a preparation method for the Chinese medicine preparation of periodontitis, comprise following processing step:
(1) Herba Clinopodii megalanthi, Periostracum Cicadae, Clematis filamentosa Dunn, Herba Eupatorii, Radix seu folium abelmoschi moschati, Aster panduratus Nees ex Walper, Herba Lophatheri, Herba Cyathulae Prostratae and Radix Capparis Membranaceae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.12 ~ 1.15, for subsequent use;
(2) xanthorrhiza and Fructus Mori are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 50% of 3 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.14, for subsequent use;
(3) Flos Jasmini Nudiflori and Resina Ferulae are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Sucus Cocois and Herba Spirodelae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) Cortex querci dentatae is put into dirt fire combustion, burn till Lycoperdon polymorphum Vitt, taking-up is ground into powder, crosses 200 order fine powders, for subsequent use.
(6) by thick paste, fine powder and the juice mix homogeneously obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the Chinese medicine preparation for the treatment of periodontitis of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Clinopodii megalanthi 77g Periostracum Cicadae 72g xanthorrhiza 72g Flos Jasmini Nudiflori 67g
Clematis filamentosa Dunn 67g Herba Eupatorii 62g Sucus Cocois 62g Resina Ferulae 57g
Radix seu folium abelmoschi moschati 57g Aster panduratus Nees ex Walper 52g Cortex querci dentatae 47g Fructus Mori 42g
Herba Lophatheri 42g Herba Cyathulae Prostratae 37g Herba Spirodelae 32g Radix Capparis Membranaceae 27g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Clinopodii megalanthi 72g Periostracum Cicadae 69g xanthorrhiza 67g Flos Jasmini Nudiflori 65g
Clematis filamentosa Dunn 62g Herba Eupatorii 57g Sucus Cocois 57g Resina Ferulae 52g
Radix seu folium abelmoschi moschati 52g Aster panduratus Nees ex Walper 47g Cortex querci dentatae 42g Fructus Mori 39g
Herba Lophatheri 37g Herba Cyathulae Prostratae 32g Herba Spirodelae 27g Radix Capparis Membranaceae 24g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Clinopodii megalanthi 67g Periostracum Cicadae 67g xanthorrhiza 62g Flos Jasmini Nudiflori 62g
Clematis filamentosa Dunn 57g Herba Eupatorii 52g Sucus Cocois 52g Resina Ferulae 47g
Radix seu folium abelmoschi moschati 47g Aster panduratus Nees ex Walper 42g Cortex querci dentatae 37g Fructus Mori 37g
Herba Lophatheri 32g Herba Cyathulae Prostratae 27g Herba Spirodelae 22g Radix Capparis Membranaceae 20g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Herba Clinopodii megalanthi 62g Periostracum Cicadae 62g xanthorrhiza 57g Flos Jasmini Nudiflori 57g
Clematis filamentosa Dunn 52g Herba Eupatorii 47g Sucus Cocois 47g Resina Ferulae 42g
Radix seu folium abelmoschi moschati 42g Aster panduratus Nees ex Walper 37g Cortex querci dentatae 32g Fructus Mori 32g
Herba Lophatheri 27g Herba Cyathulae Prostratae 22g Herba Spirodelae 17g Radix Capparis Membranaceae 15g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of periodontitis, select the routine clinical observation of patients with periodontitis 300 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 150 example, wherein male 72 example, women 78 example, 35 ~ 62 years old age, 48.4 years old mean age, the shortest person of the course of disease 3 days, most elder 1 month, average 15 days.Matched group 150 example, wherein male 73 example, women 77 example, 36 ~ 61 years old age, 47.4 years old mean age, the shortest person of the course of disease 4 days, most elder 2 months, average 30 days.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Matched group takes Metronidazole Tablet, oral, every day 4 times, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of, and the person of being in a bad way is usually invalid.
3, efficacy determination:
(1) cure: gingival hemorrhage, pyorrhea, disappearance of swelling and ache, tooth does not loosen.
(2) effective: gingival hemorrhage, pyorrhea, basic disappearance of swelling and ache, odontoseisis alleviates.
(3) effective: gingival hemorrhage, pyorrhea, to swell and ache and alleviate to some extent, odontoseisis alleviates to some extent.
(4) invalid: gingival hemorrhage, pyorrhea, the symptom that swells and ache have no obvious improvement.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 78 examples, effective 43 examples, effective 27 examples, invalid 2 examples, cure rate 52%, total effective rate 98.7%.
35 examples are cured, effective 24 examples, effective 26 examples, invalid 65 examples, cure rate 23.3%, total effective rate 56.7% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Feng, man, 36 years old, Yuncheng, Shanxi people, teacher, patient's red swelling of gingiva was congested, and that touches is hemorrhage, and depth of pocket 3mm, pyorrhea, odontoseisis, knocking pain, implication heat is smelly, constipation, yellowish or reddish urine.Take Chinese medicine preparation of the present invention, every day 2 times, each 1, warm water delivery service after meal, after taking 1 course for the treatment of, symptom is clearly better, and after taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
2, model, female, 45 years old, Ningbo of Zhejiang people, shop floor worker, patient was not because noting tooth hygiene for a long time, and suffer from gingivitis for many years, take Chinese medicine preparation of the present invention, after taking the 1st course for the treatment of, symptom obviously alleviates, and after taking the 2nd course for the treatment of, cures completely, does not recur so far.
3, Lee, man, 51 years old, Shandong Zibo people, engineer, patient visited red swelling of gingiva, touches hemorrhage, lower front tooth gingival enlargement, and the II degree touched loosens, and the halitosis of news, large dry stool, red tongue, yellow fur is thick.With crossing many Drug therapys, lose improvement.To our hospital afterwards, take Chinese medicine preparation of the present invention, after taking 1 course for the treatment of, symptom obviously alleviates, and after continuing to take 1 course for the treatment of, recovery from illness, follows up a case by regular visits to after half a year without recurrence.
4, Jiang, female, 60 years old, people from Zhengzhou, Hebei, retired cadre, patient was because of individual reason, and cause getting angry, tooth often aches, and uses many medicines, only serves temporary pain relieving, will recur after a time, can not cure.To our hospital afterwards, take Chinese medicine preparation of the present invention, after taking 1 course for the treatment of, symptom disappears substantially, fully recovers, follow up a case by regular visits to, do not recur so far after taking the 2nd course for the treatment of.
5, Liu, female, 31 years old, people from Dadukou District, Chongqing, teacher, patient's red swelling of gingiva was congested, and that touches is hemorrhage, and depth of pocket 3mm, pyorrhea, odontoseisis, knocking pain, implication heat is smelly, constipation, yellowish or reddish urine.Take Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom obviously alleviates, and after continuing to take 1 course for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after half a year without recurrence.
6, hole, female, 48 years old, people from Liaoyuan, Jilin, architect, patient's lower front tooth gingival enlargement, the II degree touched loosened, and the halitosis of news, large dry stool, red tongue, yellow fur is thick.Take Chinese medicine preparation of the present invention, after taking the 1st course for the treatment of, symptom is alleviated to some extent, and after taking 2 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to and do not recur so far.

Claims (4)

1. treat a Chinese medicine preparation for periodontitis, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 57 ~ 87 portions of Periostracum Cicadaes 57 ~ 82 parts of xanthorrhizas 52 ~ 82 parts of Flos Jasmini Nudifloris 52 ~ 77 parts
Clematis filamentosa Dunn 47 ~ 77 portions of Herba Eupatoriis 42 ~ 72 parts of Sucus Cocoiss 42 ~ 72 parts of Resina Ferulaes 37 ~ 67 parts
27 ~ 52 parts, Radix seu folium abelmoschi moschati 37 ~ 67 parts of Aster panduratus Nees ex Walpers 32 ~ 62 parts of Cortex querci dentatae 27 ~ 57 portions of Fructus Moris
Herba Lophatheri 22 ~ 52 parts of Herba Cyathulae Prostratae 17 ~ 47 portions of Herba Spirodelaes 12 ~ 42 parts of Radix Capparis Membranaceaes 10 ~ 37 parts.
2. a kind of Chinese medicine preparation for the treatment of periodontitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 62 ~ 82 portions of Periostracum Cicadaes 62 ~ 77 parts of xanthorrhizas 57 ~ 77 parts of Flos Jasmini Nudifloris 57 ~ 72 parts
Clematis filamentosa Dunn 52 ~ 72 portions of Herba Eupatoriis 47 ~ 67 parts of Sucus Cocoiss 47 ~ 67 parts of Resina Ferulaes 42 ~ 62 parts
32 ~ 47 parts, Radix seu folium abelmoschi moschati 42 ~ 62 parts of Aster panduratus Nees ex Walpers 37 ~ 57 parts of Cortex querci dentatae 32 ~ 52 portions of Fructus Moris
Herba Lophatheri 27 ~ 47 parts of Herba Cyathulae Prostratae 22 ~ 42 portions of Herba Spirodelaes 17 ~ 37 parts of Radix Capparis Membranaceaes 15 ~ 32 parts.
3. a kind of Chinese medicine preparation for the treatment of periodontitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 67 ~ 77 portions of Periostracum Cicadaes 67 ~ 72 parts of xanthorrhizas 62 ~ 72 parts of Flos Jasmini Nudifloris 62 ~ 67 parts
Clematis filamentosa Dunn 57 ~ 67 portions of Herba Eupatoriis 52 ~ 62 parts of Sucus Cocoiss 52 ~ 62 parts of Resina Ferulaes 47 ~ 57 parts
37 ~ 42 parts, Radix seu folium abelmoschi moschati 47 ~ 57 parts of Aster panduratus Nees ex Walpers 42 ~ 52 parts of Cortex querci dentatae 37 ~ 47 portions of Fructus Moris
Herba Lophatheri 32 ~ 42 parts of Herba Cyathulae Prostratae 27 ~ 37 portions of Herba Spirodelaes 22 ~ 32 parts of Radix Capparis Membranaceaes 20 ~ 27 parts.
4. a kind of Chinese medicine preparation for the treatment of periodontitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Clinopodii megalanthi 72 portions of Periostracum Cicadaes 69 parts of xanthorrhizas 67 parts of Flos Jasmini Nudifloris 65 parts
Clematis filamentosa Dunn 62 portions of Herba Eupatoriis 57 parts of Sucus Cocoiss 57 parts of Resina Ferulaes 52 parts
39 parts, Radix seu folium abelmoschi moschati 52 parts of Aster panduratus Nees ex Walpers 47 parts of Cortex querci dentatae 42 portions of Fructus Moris
Herba Lophatheri 37 parts of Herba Cyathulae Prostratae 32 portions of Herba Spirodelaes 27 parts of Radix Capparis Membranaceaes 24 parts.
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