CN104547180A - Cream for treating chilblain and preparation method for cream - Google Patents

Cream for treating chilblain and preparation method for cream Download PDF

Info

Publication number
CN104547180A
CN104547180A CN201410827866.XA CN201410827866A CN104547180A CN 104547180 A CN104547180 A CN 104547180A CN 201410827866 A CN201410827866 A CN 201410827866A CN 104547180 A CN104547180 A CN 104547180A
Authority
CN
China
Prior art keywords
extract
parts
leachate
traditional chinese
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410827866.XA
Other languages
Chinese (zh)
Inventor
杨辉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
XINING YIGE INTELLECTUAL PROPERTY ADVISORY SERVICES Co Ltd
Original Assignee
XINING YIGE INTELLECTUAL PROPERTY ADVISORY SERVICES Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by XINING YIGE INTELLECTUAL PROPERTY ADVISORY SERVICES Co Ltd filed Critical XINING YIGE INTELLECTUAL PROPERTY ADVISORY SERVICES Co Ltd
Priority to CN201410827866.XA priority Critical patent/CN104547180A/en
Publication of CN104547180A publication Critical patent/CN104547180A/en
Pending legal-status Critical Current

Links

Abstract

The invention discloses cream for treating chilblain and a preparation method for the cream. The cream comprises the following traditional Chinese medicine extracts in parts by weight: 9-11 parts of a Chinese angelica extract, 4-6 parts of a radix glycyrrhizae extract, 5-8 parts of a caulis akebiae extract, 2-4 parts of a fructus evodiae extract, 10-15 parts of an astragalus extract, 3-8 parts of a garden balsam stem extract, further comprises 20-25 parts of an oil lubricating agent, 10-20 parts of gelatin and 5-10 parts of purified water. The preparation method for the cream comprises the following steps: (1) preparing the extract of each traditional Chinese medicine; (2) preparing sol; (3) preparing ointment; (4) bottling. A method of combining alcohol extraction and water extraction is used to extract the traditional Chinese medicine extracts, so that the extraction efficiency is high and purity of the extract is relatively high. The cream prepared from the traditional Chinese medicine extract can be used for curing the chilblain without a relapse, is free of side effect, quick in effect-taking, and can be used for effectively preventing the chilblain. Various traditional Chinese medicine raw materials in the cream are traditional Chinese medicine materials with relatively low price, so that the material cost is low.

Description

One treats chilblain emulsifiable paste and preparation method thereof
Technical field
The present invention relates to Chinese drug preparation technique field, be specifically related to one and treat chilblain emulsifiable paste and preparation method thereof.
Background technology
Chilblain is common in winter, and due to local skin erythema, the tumidus infringement repeatedly that very cold causes, vesicle, ulcer can appear in severe patient, and the course of disease is slow, and weather turns warm rear spontaneous recovery, easily recurs.The effect of drugs being used for the treatment of chilblain is at present all not obvious, and treatment speed is slow, controls recurrence rate after healing very high, so chilblain patient expects to occur a kind of medicine for the treatment of chilblain very much, therapeutic effect is obvious, controls recurrence rate after healing anxious low.
Summary of the invention
For the problem proposed in background technology, the invention provides with Chinese medicine extract is that the one of raw material treats chilblain emulsifiable paste and preparation method thereof, can effectively prevent and treat and treat chilblain.
Treatment chilblain emulsifiable paste provided by the invention, comprise the Chinese medicine extract of following weight portion, Radix Angelicae Sinensis extract 9-11 part, Radix Glycyrrhizae extract 4-6 part, Caulis Akebiae extract 5-8 part, Fructus Evodiae extract 2-4 part, Radix Astragali extract 10-15 part, Herba speranskiae tuberculatae extract 3-8 part, also comprise cunning dose of 20-25 part, gelatin 10-20 part purified water 5-10 part
The preparation method for the treatment of chilblain emulsifiable paste provided by the invention, its preparation process is as follows:
(1) extract of each Chinese medicine is prepared
Adopt the method for water extraction+alcohol extraction to extract Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract respectively, concrete extracting method is:
Each Chinese crude drug cleans respectively, clean after to be crushed to particle diameter 2-5mm be traditional Chinese medicinal material raw materials medicine,
Traditional Chinese medicinal material raw materials medicine humidification is to water content 40-60%, heat to 30-35 degree, be incubated 24-36 hours, the traditional Chinese medicinal material raw materials medicine 24-30 hours through humidification, humidification and insulation is extracted with traditional Chinese medicinal material raw materials medicine 6-8 times of quality 70-75% ethanol dynamic circulation, reclaim ethanol, concentrated alcohol extract, to relative density 1-1.5, obtains fluid extract m;
Residue adds the water of traditional Chinese medicinal material raw materials medicine 4 times of quality, keeps slight boiling condition to extract 2 hours, filters and obtain leachate a;
Filtering residue adds the water of crude drug quality 4 times, keeps slight boiling condition to extract 2 hours, filters and obtain leachate b;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate c;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate d;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate f;
Merge leachate a, leachate b, leachate c, leachate d and leachate f, be concentrated into density 1.16-1.20, obtain fluid extract n;
Mixed flow extractum m and fluid extract n, adjusts cream relative density 1.16-1.20;
Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract is obtained respectively after drying;
(2) colloidal sol
Take by weight purified water, cunning dose, gelatin is stand-by, purified water and cunning dose dropped into colloidal sol pot, temperature to 70-80 DEG C, drops into gelatin, stir gelatin is all dissolved, degassed, filter, obtain glue, insulation, stand-by;
(3) ointment is prepared
Take Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract by weight, Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract are mixed 30-40min in mixer and obtains extract mixtures, again the mixture of extract is put in glue, putting into mixer mixing 40-60min makes Chinese medicine extract be dissolved completely in glue, cooling, degassedly obtains emulsifiable paste;
(4) bottle
Extruder is cleaned, then with the ethanol of 75%, the cavity of extruder is sterilized, rinse 3-5 time by purified water after sterilization, emulsifiable paste is joined in extruder, be expressed in emulsifiable paste bottle by extruder, seal, add a cover, pack.
Preferably, described cunning dose is the one of vaseline, paraffin or stearin.
Beneficial effect of the present invention is: the invention provides a kind of method and the using method thereof that take Chinese medicine extract as raw material and prepare treatment chilblain emulsifiable paste, the method of alcohol extraction+water extraction is used to extract Chinese medicine extract, extraction ratio is high, the purity extracted is also high, use the emulsifiable paste that Chinese medicine extract is obtained, more chilblain can be effected a radical cure, after healing no longer recurrent exerbation and be free from side effects, instant effect, and can effective anti-frostbite, various Chinese herbs in the present invention are all the Chinese crude drugs that price is lower, and the cost of material is low.
Detailed description of the invention
The present invention will be further described below:
Embodiment one:
A kind of take Chinese medicine extract as the treatment chilblain emulsifiable paste of raw material, comprise the Chinese medicine extract of following weight portion, Radix Angelicae Sinensis extract 9 parts, Radix Glycyrrhizae extract 6 parts, Caulis Akebiae extract 5 parts, Fructus Evodiae extract 4 parts, Radix Astragali extract 10 parts, Herba speranskiae tuberculatae extract 8 parts, also comprise 20 parts, vaseline, gelatin 20 parts of purified water 5 parts, its preparation methods steps is as follows:
(1) extract of each Chinese medicine is prepared
Adopt the method for water extraction+alcohol extraction to extract Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract respectively, concrete extracting method is:
Each Chinese crude drug cleans respectively, clean after to be crushed to particle diameter 2-5mm be traditional Chinese medicinal material raw materials medicine,
Traditional Chinese medicinal material raw materials medicine humidification is to water content 40-60%, heat to 30-35 degree, be incubated 24-36 hours, the traditional Chinese medicinal material raw materials medicine 24-30 hours through humidification, humidification and insulation is extracted with traditional Chinese medicinal material raw materials medicine 6-8 times of quality 70-75% ethanol dynamic circulation, reclaim ethanol, concentrated alcohol extract, to relative density 1-1.5, obtains fluid extract m;
Residue adds the water of traditional Chinese medicinal material raw materials medicine 4 times of quality, keeps slight boiling condition to extract 2 hours, filters and obtain leachate a;
Filtering residue adds the water of crude drug quality 4 times, keeps slight boiling condition to extract 2 hours, filters and obtain leachate b;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate c;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate d;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate f;
Merge leachate a, leachate b, leachate c, leachate d and leachate f, be concentrated into density 1.16-1.20, obtain fluid extract n;
Mixed flow extractum m and fluid extract n, adjusts cream relative density 1.16-1.20;
Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract is obtained respectively after drying;
(2) colloidal sol
Take purified water by weight, vaseline, gelatin be stand-by, purified water and vaseline are dropped into colloidal sol pot, temperature to 70-80 DEG C, drops into gelatin, stir gelatin is all dissolved, degassed, filter, obtain glue, insulation, stand-by;
(3) ointment is prepared
Take Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract by weight, Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract are mixed 30-40min in mixer and obtains extract mixtures, again the mixture of extract is put in glue, putting into mixer mixing 40-60min makes Chinese medicine extract be dissolved completely in glue, cooling, degassedly obtains emulsifiable paste;
(4) bottle
Extruder is cleaned, then with the ethanol of 75%, the cavity of extruder is sterilized, rinse 3-5 time by purified water after sterilization, emulsifiable paste is joined in extruder, be expressed in emulsifiable paste bottle by extruder, seal, add a cover, pack.
People from Hunan Mr. Shang of present inhabitation Xining, Qinghai, after coming Xining, winter there is abnormality in hand: ten refer to enlargement, the back of the hand place skin aubergine, and with festering, without the general pale asphyxia of rotten position finger extruding, be diagnosed as chilblain, the weight portion that Mr. Shang proposes by the present embodiment has prepared various raw material, and use by the method that the present embodiment proposes, after 8 days, the back of the hand chilblain position rotten position heals, and after 25 days, hand is subsided a swelling completely, stop using 15 days after detumescence, frostbite of hand is without recurrence.
People from Anhui Mrs Fang of present inhabitation Xining, Qinghai, after coming Xining, winter there is abnormality in foot: ten refer to enlargement, instep place skin aubergine, and with festering, without the general pale asphyxia of rotten position finger extruding, be diagnosed as chilblain, Mrs Fang employs emulsifiable paste of the present invention, after 13 days, instep chilblain position rotten position heals, within 35 days, subside a swelling completely with rear feet, stop using 19 days after detumescence, frostbite of foot is without recurrence.
Embodiment two:
A kind of take Chinese medicine extract as the treatment chilblain emulsifiable paste of raw material, comprise the Chinese medicine extract of following weight portion, Radix Angelicae Sinensis extract 11 parts, Radix Glycyrrhizae extract 4 parts, Caulis Akebiae extract 8 parts, Fructus Evodiae extract 2 parts, Radix Astragali extract 15 parts, Herba speranskiae tuberculatae extract 3 parts, also comprise 25 parts, paraffin, gelatin 10 parts of purified water 10 parts, its preparation methods steps is as follows:
(1) extract of each Chinese medicine is prepared
Adopt the method for water extraction+alcohol extraction to extract Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract respectively, concrete extracting method is:
Each Chinese crude drug cleans respectively, clean after to be crushed to particle diameter 2-5mm be traditional Chinese medicinal material raw materials medicine,
Traditional Chinese medicinal material raw materials medicine humidification is to water content 40-60%, heat to 30-35 degree, be incubated 24-36 hours, the traditional Chinese medicinal material raw materials medicine 24-30 hours through humidification, humidification and insulation is extracted with traditional Chinese medicinal material raw materials medicine 6-8 times of quality 70-75% ethanol dynamic circulation, reclaim ethanol, concentrated alcohol extract, to relative density 1-1.5, obtains fluid extract m;
Residue adds the water of traditional Chinese medicinal material raw materials medicine 4 times of quality, keeps slight boiling condition to extract 2 hours, filters and obtain leachate a;
Filtering residue adds the water of crude drug quality 4 times, keeps slight boiling condition to extract 2 hours, filters and obtain leachate b;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate c;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate d;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate f;
Merge leachate a, leachate b, leachate c, leachate d and leachate f, be concentrated into density 1.16-1.20, obtain fluid extract n;
Mixed flow extractum m and fluid extract n, adjusts cream relative density 1.16-1.20;
Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract is obtained respectively after drying;
(2) colloidal sol
Take purified water by weight, paraffin, gelatin be stand-by, purified water and paraffin are dropped into colloidal sol pot, temperature to 70-80 DEG C, drops into gelatin, stir gelatin is all dissolved, degassed, filter, obtain glue, insulation, stand-by;
(3) ointment is prepared
Take Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract by weight, Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract are mixed 30-40min in mixer and obtains extract mixtures, again the mixture of extract is put in glue, putting into mixer mixing 40-60min makes Chinese medicine extract be dissolved completely in glue, cooling, degassedly obtains emulsifiable paste;
(4) bottle
Extruder is cleaned, then with the ethanol of 75%, the cavity of extruder is sterilized, rinse 3-5 time by purified water after sterilization, emulsifiable paste is joined in extruder, be expressed in emulsifiable paste bottle by extruder, seal, add a cover, pack.
People from Henan Mr. Wang of present inhabitation Xining, Qinghai, after coming Xining, winter there is abnormality in hand: ten refer to enlargement, the back of the hand place skin aubergine, and with festering, without the general pale asphyxia of rotten position finger extruding, be diagnosed as chilblain, Mr. Wang employs emulsifiable paste of the present invention, after 8 days, the back of the hand chilblain position rotten position heals, after 25 days, hand is subsided a swelling completely, and stop using 15 days after detumescence, frostbite of hand is without recurrence.
People from Jiangxi Liu Nvshi of present inhabitation Xining, Qinghai, after coming Xining, winter there is abnormality in foot: ten refer to enlargement, instep place skin aubergine, and with festering, without the general pale asphyxia of rotten position finger extruding, be diagnosed as chilblain, Mrs Liu employs emulsifiable paste of the present invention, after 13 days, instep chilblain position rotten position heals, within 35 days, subside a swelling completely with rear feet, stop using 19 days after detumescence, frostbite of foot is without recurrence.
Embodiment three:
A kind of take Chinese medicine extract as the treatment chilblain emulsifiable paste of raw material, comprise the Chinese medicine extract of following weight portion, Radix Angelicae Sinensis extract 10 parts, Radix Glycyrrhizae extract 5 parts, Caulis Akebiae extract 6 parts, Fructus Evodiae extract 3 parts, Radix Astragali extract 13 parts, Herba speranskiae tuberculatae extract 6 parts, also comprise stearin 23 parts, gelatin 15 parts of purified water 8 parts, its preparation methods steps is as follows:
(1) extract of each Chinese medicine is prepared
Adopt the method for water extraction+alcohol extraction to extract Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract respectively, concrete extracting method is:
Each Chinese crude drug cleans respectively, clean after to be crushed to particle diameter 2-5mm be traditional Chinese medicinal material raw materials medicine,
Traditional Chinese medicinal material raw materials medicine humidification is to water content 40-60%, heat to 30-35 degree, be incubated 24-36 hours, the traditional Chinese medicinal material raw materials medicine 24-30 hours through humidification, humidification and insulation is extracted with traditional Chinese medicinal material raw materials medicine 6-8 times of quality 70-75% ethanol dynamic circulation, reclaim ethanol, concentrated alcohol extract, to relative density 1-1.5, obtains fluid extract m;
Residue adds the water of traditional Chinese medicinal material raw materials medicine 4 times of quality, keeps slight boiling condition to extract 2 hours, filters and obtain leachate a;
Filtering residue adds the water of crude drug quality 4 times, keeps slight boiling condition to extract 2 hours, filters and obtain leachate b;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate c;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate d;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate f;
Merge leachate a, leachate b, leachate c, leachate d and leachate f, be concentrated into density 1.16-1.20, obtain fluid extract n;
Mixed flow extractum m and fluid extract n, adjusts cream relative density 1.16-1.20;
Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract is obtained respectively after drying;
(2) colloidal sol
Take purified water by weight, stearin, gelatin be stand-by, purified water and stearin are dropped into colloidal sol pot, temperature to 70-80 DEG C, drops into gelatin, stir gelatin is all dissolved, degassed, filter, obtain glue, insulation, stand-by;
(3) ointment is prepared
Take Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract by weight, Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract are mixed 30-40min in mixer and obtains extract mixtures, again the mixture of extract is put in glue, putting into mixer mixing 40-60min makes Chinese medicine extract be dissolved completely in glue, cooling, degassedly obtains emulsifiable paste;
(4) bottle
Extruder is cleaned, then with the ethanol of 75%, the cavity of extruder is sterilized, rinse 3-5 time by purified water after sterilization, emulsifiable paste is joined in extruder, be expressed in emulsifiable paste bottle by extruder, seal, add a cover, pack.
The Shanghai people Mr. Zhang of present inhabitation Xining, Qinghai, after coming Xining, winter there is abnormality in hand: ten refer to enlargement, the back of the hand place skin aubergine, and with festering, without the general pale asphyxia of rotten position finger extruding, be diagnosed as chilblain, Mr. Zhang employs emulsifiable paste of the present invention, after 9 days, the back of the hand chilblain position rotten position heals, after 28 days, hand is subsided a swelling completely, and stop using 16 days after detumescence, frostbite of hand is without recurrence.
People from Chongqing Jin Nvshi of present inhabitation Xining, Qinghai, after coming Xining, winter there is abnormality in foot: ten refer to enlargement, instep place skin aubergine, and with festering, without the general pale asphyxia of rotten position finger extruding, be diagnosed as chilblain, Mrs Jin employs emulsifiable paste of the present invention, after 15 days, instep chilblain position rotten position heals, within 33 days, subside a swelling completely with rear feet, stop using 23 days after detumescence, frostbite of foot is without recurrence.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technology people of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.

Claims (3)

1. a treatment chilblain emulsifiable paste, it is characterized in that, comprise the Chinese medicine extract of following weight portion, Radix Angelicae Sinensis extract 9-11 part, Radix Glycyrrhizae extract 4-6 part, Caulis Akebiae extract 5-8 part, Fructus Evodiae extract 2-4 part, Radix Astragali extract 10-15 part, Herba speranskiae tuberculatae extract 3-8 part, also comprise cunning dose of 20-25 part, gelatin 10-20 part purified water 5-10 part.
2. the preparation method for the treatment of chilblain emulsifiable paste as claimed in claim 1, is characterized in that, comprise the following steps:
(1) extract of each Chinese medicine is prepared
Adopt the method for water extraction+alcohol extraction to extract Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract respectively, concrete extracting method is:
Each Chinese crude drug cleans respectively, clean after to be crushed to particle diameter 2-5mm be traditional Chinese medicinal material raw materials medicine,
Traditional Chinese medicinal material raw materials medicine humidification is to water content 40-60%, heat to 30-35 degree, be incubated 24-36 hours, the traditional Chinese medicinal material raw materials medicine 24-30 hours through humidification, humidification and insulation is extracted with traditional Chinese medicinal material raw materials medicine 6-8 times of quality 70-75% ethanol dynamic circulation, reclaim ethanol, concentrated alcohol extract, to relative density 1-1.5, obtains fluid extract m;
Residue adds the water of traditional Chinese medicinal material raw materials medicine 4 times of quality, keeps slight boiling condition to extract 2 hours, filters and obtain leachate a;
Filtering residue adds the water of crude drug quality 4 times, keeps slight boiling condition to extract 2 hours, filters and obtain leachate b;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate c;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate d;
Filtering residue adds crude drug quality 4 times of water gagings, keeps slight boiling condition to extract 2 hours, filters and obtain leachate f;
Merge leachate a, leachate b, leachate c, leachate d and leachate f, be concentrated into density 1.16-1.20, obtain fluid extract n;
Mixed flow extractum m and fluid extract n, adjusts cream relative density 1.16-1.20;
Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract is obtained respectively after drying;
(2) colloidal sol
Take by weight purified water, cunning dose, gelatin is stand-by, purified water and cunning dose dropped into colloidal sol pot, temperature to 70-80 DEG C, drops into gelatin, stir gelatin is all dissolved, degassed, filter, obtain glue, insulation, stand-by;
(3) ointment is prepared
Take Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract by weight, Radix Angelicae Sinensis extract, Radix Glycyrrhizae extract, Caulis Akebiae extract, Fructus Evodiae extract, Radix Astragali extract, Herba speranskiae tuberculatae extract are mixed 30-40min in mixer and obtains extract mixtures, again the mixture of extract is put in glue, putting into mixer mixing 40-60min makes Chinese medicine extract be dissolved completely in glue, cooling, degassedly obtains emulsifiable paste;
(4) bottle
Extruder is cleaned, then with the ethanol of 75%, the cavity of extruder is sterilized, rinse 3-5 time by purified water after sterilization, emulsifiable paste is joined in extruder, be expressed in emulsifiable paste bottle by extruder, seal, add a cover, pack.
3. the preparation method for the treatment of chilblain emulsifiable paste according to claim 2, is characterized in that, described cunning dose is one or more of vaseline, paraffin or stearin.
CN201410827866.XA 2014-12-29 2014-12-29 Cream for treating chilblain and preparation method for cream Pending CN104547180A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410827866.XA CN104547180A (en) 2014-12-29 2014-12-29 Cream for treating chilblain and preparation method for cream

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410827866.XA CN104547180A (en) 2014-12-29 2014-12-29 Cream for treating chilblain and preparation method for cream

Publications (1)

Publication Number Publication Date
CN104547180A true CN104547180A (en) 2015-04-29

Family

ID=53064951

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410827866.XA Pending CN104547180A (en) 2014-12-29 2014-12-29 Cream for treating chilblain and preparation method for cream

Country Status (1)

Country Link
CN (1) CN104547180A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105561058A (en) * 2016-01-08 2016-05-11 王芳存 Traditional Chinese medicine patch for mainly treating chilblain and preparation method thereof
CN105561057A (en) * 2016-01-08 2016-05-11 王芳存 Medicinal liquid for treating frostbite and preparation method thereof
CN105560986A (en) * 2016-01-08 2016-05-11 王芳存 Inflammation eliminating and pain relieving preparation for treating chilblain and preparation method thereof
CN108079131A (en) * 2018-01-18 2018-05-29 南宁圣特生物科技有限公司 Deep layer maintenance anti-inflammatory anti-itch kibe ointment of essential oil containing camellia seed and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103705892A (en) * 2013-12-30 2014-04-09 孙亚平 Traditional Chinese medicine composition for treating chilblain
CN103933517A (en) * 2014-04-18 2014-07-23 李存好 Traditional Chinese medicine preparation for treating chilblain and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103705892A (en) * 2013-12-30 2014-04-09 孙亚平 Traditional Chinese medicine composition for treating chilblain
CN103933517A (en) * 2014-04-18 2014-07-23 李存好 Traditional Chinese medicine preparation for treating chilblain and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105561058A (en) * 2016-01-08 2016-05-11 王芳存 Traditional Chinese medicine patch for mainly treating chilblain and preparation method thereof
CN105561057A (en) * 2016-01-08 2016-05-11 王芳存 Medicinal liquid for treating frostbite and preparation method thereof
CN105560986A (en) * 2016-01-08 2016-05-11 王芳存 Inflammation eliminating and pain relieving preparation for treating chilblain and preparation method thereof
CN108079131A (en) * 2018-01-18 2018-05-29 南宁圣特生物科技有限公司 Deep layer maintenance anti-inflammatory anti-itch kibe ointment of essential oil containing camellia seed and preparation method thereof

Similar Documents

Publication Publication Date Title
CN102178809B (en) Externally-applied medicament for skin and method for processing medicament into preparation
CN106798608B (en) A kind of wax therapy wax mud and preparation method thereof
CN104306514A (en) Traditional Chinese medicine spray and preparation method thereof
CN104547180A (en) Cream for treating chilblain and preparation method for cream
CN106362129A (en) Medicinal liquor for treating chilblains
CN103830366B (en) Traditional Chinese medicine micropowder for treating swine streptococcosis and preparation method thereof
CN111888444A (en) Composition for promoting blood circulation and removing obstruction in channels for repairing internal fistula after puncture, preparation method and preparation
CN105079747A (en) Chilblain ointment for hands and preparation method of chilblain ointment
CN105456980A (en) Antipyretic patch for treating winter cold and fever and preparation method of antipyretic patch
CN105148240A (en) Medicinal preparation used for treating chronic cardiac failure
CN101234139A (en) Proprietary Chinese medicine for curing common cold and preparation thereof
CN103893243A (en) Method for extracting jatropha curcas branch and leaf extract and foot bath formula
CN103623169A (en) Traditional Chinese medicine composition for treating haemorrhoids
CN108553543A (en) A kind of zicao soft plaster and preparation method thereof
CN103432289B (en) A kind of Chinese medicine oral liquid for the treatment of pig eczema and preparation method thereof
CN102038906A (en) Medicament for treating psoriasis
CN104069470A (en) Traditional Chinese medicine preparation for treating chilblain
CN105362972A (en) Preparation method of externally used chilblain treatment tincture
CN105941703A (en) Instant tea for treating Yin deficiency type headache and preparation method of instant tea
CN105125896A (en) Pharmaceutical preparation for treating migraine
CN104043039A (en) Rhizoma Coptidis ointment and preparation method thereof
CN101978997B (en) Externally-applied cream for treating wind-heat cold by adopting transdermal absorption technology
CN102614298B (en) Scalding spray and preparation method thereof
CN112843166A (en) Health-preserving health-care powder
CN103816321A (en) Traditional Chinese medicine liquid for treating dermatophytosis

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
EXSB Decision made by sipo to initiate substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150429

WD01 Invention patent application deemed withdrawn after publication