CN104546663B - A kind of phalacrosis prevention and hair generation shampoo containing series bacillus - Google Patents
A kind of phalacrosis prevention and hair generation shampoo containing series bacillus Download PDFInfo
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- CN104546663B CN104546663B CN201410826081.0A CN201410826081A CN104546663B CN 104546663 B CN104546663 B CN 104546663B CN 201410826081 A CN201410826081 A CN 201410826081A CN 104546663 B CN104546663 B CN 104546663B
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Abstract
The present invention provides a kind of phalacrosis prevention and hair generation shampoo containing series bacillus, the shampoo of anti-dandruff anti-shed hair growth liquid, 84.74 91.5wt.% comprising 8.5 15.26wt.%；Described anti-dandruff anti-shed hair growth liquid is that mass ratio is 1:196‑4:198 series bacillus and acetic acid.Beneficial effects of the present invention are：The present invention is added in shampoo using anti-dandruff phalacrosis prevention and hair generation shampoo, and the enzyme and antibacterial material that series bacillus is produced make shampoo have antibacterial activity, is a kind of formula and the simple phalacrosis prevention and hair generation shampoo of manufacture method.
Description
Technical field
The present invention relates to a kind of phalacrosis prevention and hair generation shampoo, especially a kind of phalacrosis prevention and hair generation shampoo containing series bacillus.
Background technology
Dandruff medically be referred to as capitis pityriasis, be one kind by chlosma（One kind in fungi）Caused skin
Disease.Amount reproduction of the chlosma on scalp causes the hyperplasia of scalp cuticula, so as to promote corneocyte with white
The form of color or the grey scales of skin that peel off comes off extremely, this scales of skin that peel off come off as dandruff.Dandruff Producing reason is generally divided into life
Rationality and pathologic.
Dandruff is that the scalp ecological balance is caused by destroying.In fact, the scalp ecological environment of health is by the balance of finance, credits and materials
Maintain：Grease, flora, metabolic balance.When scalp fat secretion is unbalance, scalp fuel-displaced will become greasy；When scalp flora ring
Border is unbalance, and harmful bacteria largely grows, and the phenomenon that head is itched just occurs；And scalp stratum corneum is too fast, comes off and just form dandruff.
The antifungal drug clinically for treatment of dandruff dandruff fungi has ketoconazole, Climbazole, two sulphur at present
Change selenium etc., wherein ketoconazole effect in terms for the treatment of of dandruff is best.
Ketoconazole can suppress the synthesis of fungi ergosterol in low concentration, play a part of suppressing chlosma breeding；
Fungal cell membrane is then directly destroyed during high concentration, extremely strong bactericidal effect is shown.Ketoconazole enemy's hide collagen has higher parent
And power, diaphragm can be quickly formed on scalp top layer, so as to persistently play a role.In addition, Transdermal absorption, tool is not present in ketoconazole
There is very high security.
Cuticula cracking-off agent can effectively remove a certain proportion of corneocyte, alleviate clinical symptoms to a certain extent, this
Class product includes coal tar, sulphur and salicylic acid；This kind of product application for a long time can destroy epidermal structure, upset epidermis itself and put down
Weighing apparatus, and influence hair quality.
Cytostatic agent mainly reduces corneocyte and substitutes speed, extensive with cuticula cycle period length
Multiple, the process of angling and furfur makes moderate progress, but many clinical trials show that this kind of medicine can not control dandruff well
Clinical symptoms；It is special and its main component excitant is strong, feels rough using rear hair quality, it is also possible to cause some cosmetic problems
It is not some sensitive, and there is peculiar smell etc..
Alopecia seborrheica is currently global problem.The file of Patent No. 201010033994 provides a kind of trophonema
Capsule, Anti-hair loss, strengthen the hair composition and its manufacture method, are related to the extractive technique of plurality of Chinese, and formula is complicated, and technique is cumbersome.
The content of the invention
In view of the shortcomings of the prior art, the present invention provides a kind of formula and the simple phalacrosis prevention and hair generation shampoo of manufacture method.
The technical scheme is that：A kind of phalacrosis prevention and hair generation shampoo containing series bacillus, includes 8.5-15.26
Wt.% anti-dandruff anti-shed hair growth liquid, 84.74-91.5 wt.% shampoo.
Described anti-dandruff anti-shed hair growth liquid is that mass ratio is 1:196-4:198 series bacillus and acetic acid.
Described shampoo includes 68.91-84.76 wt.% water, 10-15wt.% laureth sulfuric ester
Ammonium, 2-7wt.% lauroylamidopropyl betaine, 1-3wt.% bay alcohol sulfuric ester ammonium, 1-3wt.% coconut oil diethyl
Alkylolamides, 0.5-1.2wt.% ammonium chloride, 0.5-1wt.% essence, 0.1-0.5wt.% melon glue Hydroxyproyl Trimethyl
Ammonium chloride, 0.05-0.15wt.% disodium EDTA, 0.03-0.07wt.% methylchloroisothiazandnone,
0.03-0.07wt.% methylisothiazolinone, 0.03-0.1wt.% citric acid.
The present invention also provides a kind of preparation method of the phalacrosis prevention and hair generation shampoo containing series bacillus, it is characterised in that：Bag
Include
Step one：Shampoo is prepared, preparation order is as follows：
（1）The cold water of 27.564-33.904 parts by weight is added into reaction pot, stirring is opened, high speed homogenization adds 0.1-
The guar hydroxypropyltrimonium chloride of 0.5 parts by weight, homogeneous 15min, the citric acid of addition 0.03-0.1 parts by weight,
The disodium EDTA of 0.05-0.15 parts by weight, then homogeneous 5min, after checking without clustering phenomena, begin to warm up；
（2）80~85 DEG C are heated to while stirring, stop heating；
（3）High speed homogenization is opened, laureth sulfuric ester ammonium, the 1-3 parts by weight laruyl alcohol sulphur of 10-15 parts by weight is added
Acid esters ammonium, homogeneous stirring 30min；
（4）Shutdown disappears after most of bubble, starts to supplement the water of 27.564-33.904 parts by weight, current are avoided during moisturizing
Impact foaming；
（5）Cooling water is opened, stirring at low speed is cooled to less than 45 DEG C；
（6）Add the coconut oil diethanol amides of 1-3 parts by weight, the lauroylamidopropyl betaine of 2-7 parts by weight,
Essence, the methylchloroisothiazandnone of 0.03-0.07 parts by weight, the methyl of 0.03-0.07 parts by weight of 0.5-1 parts by weight
OIT is stirred；
（7）Sample is first taken to test the ammonium chloride of 0.5-1.2 parts by weight, the cold water with 13.782-16.952 parts by weight is molten
Stirring 30min in pot is added after solution；
Step 2：Anti-dandruff anti-shed hair growth liquid is added, concrete operations are as follows：
Shampoo is cooled to 30 ± 2 DEG C, anti-dandruff anti-shed hair growth liquid stirring is added, must not homogeneous.
Beneficial effects of the present invention are：The present invention is added in shampoo using anti-dandruff phalacrosis prevention and hair generation shampoo, class bud
The enzyme and antibacterial material that spore bacillus produces make shampoo have antibacterial activity, are a kind of formula and the simple anticreep of manufacture method
Hair tonic shampoo.
Embodiment
The embodiment to the present invention is described further below：
A kind of phalacrosis prevention and hair generation shampoo containing series bacillus, the anti-dandruff anti-shed hair growth liquid comprising 8.5-15.26 wt.%,
84.74-91.5 wt.% shampoo.
Described anti-dandruff anti-shed hair growth liquid is that mass ratio is 1:196-4:198 series bacillus and acetic acid.
Described shampoo includes 80wt.% water, 15wt.% laureth sulfuric ester ammonium, the 2wt.% moon
Bay alcohol sulfuric ester ammonium, 1wt.% coconut oil diethanol amide, the 0.5-1.2wt.% of osmanthus amido propyl betaine, 3wt.%
Ammonium chloride, 0.5wt.% essence, 0.1-0.5wt.% guar hydroxypropyltrimonium chloride, 0.05-0.15wt.%
Disodium EDTA, 0.03wt.% methylchloroisothiazandnone, 0.03wt.% methylisothiazolinone,
0.03wt.% citric acid.
The preparation method specific embodiment of the phalacrosis prevention and hair generation shampoo containing series bacillus of this programme is as follows：
Step one：Shampoo is prepared, preparation order is as follows：
（1）40 parts by weight cold water are added into reaction pot, stirring is opened, high speed homogenization adds the melon glue of 0.1 parts by weight
Hydroxypropyl-trimethyl ammonium chloride, homogeneous 15min adds citric acid, the ethylenediamine tetrem of 0.05 parts by weight of 0.03 parts by weight
Acid disodium salt, then homogeneous 5min, after checking without clustering phenomena, begin to warm up；
（2）80~85 DEG C are heated to while stirring, stop heating.
（3）High speed homogenization is opened, laureth sulfuric ester ammonium, the 3 parts by weight bay alcohol sulfuric esters of 15 parts by weight are added
Ammonium, homogeneous stirring 30min.
（4）Shutdown disappears after most of bubble, starts to supplement the water of 32.36 parts by weight, avoids water impact to rise during moisturizing
Bubble.
（5）Cooling water is opened, stirring at low speed is cooled to less than 45 DEG C.
（6）Add the coconut oil diethanol amide, the lauroylamidopropyl betaine of 2 parts by weight, 0.5 weight of 1 parts by weight
Essence, the methylchloroisothiazandnone of 0.03 parts by weight, the methylisothiazolinone of 0.03 parts by weight for measuring part are stirred.
（7）First take sample to test the ammonium chloride of 0.9 parts by weight, stirred with being added after the cold-water solution of 5 parts by weight in pot
Mix 30min.
Step 2：Anti-dandruff anti-shed hair growth liquid is added, concrete operations are as follows：30 ± 2 DEG C are cooled to, anti-dandruff phalacrosis prevention and hair generation is added
Liquid is stirred, must not homogeneous.
Then carry out the qualified rear enclosure screen pack of sense organ, pH, viscosity measurements to mixed liquor to discharge, magazine is inside and outside clean
Only, inwall 70~75wt.% alcohol disinfectings, then the poly-bag that liner was sterilized；It is further complete that discharging samples progress simultaneously
Face detect, it is qualified after can be filling.
The series bacillus somatic cells that the present invention is used are in shaft-like, and gram chromosome is positive, negative or variable；With week
Raw flagellum movement；Gemma is produced, soluble pigment, amphimicrobian or strict aerobic are not produced on nutrient agar.Institute of the present invention
The catalase for the series bacillus strain stated is the positive, and oxydase reaction is variable；V-P reactions are variable；Hydrogen sulfide is not produced, it is individual
Indoles Zhong not produced；The hydrolysis of casein, starch and urea element is variable, and nitrate reduction is variable to nitrite, tyrosine catabolic
It is variable；Optimal pH is 7.0, most several 28-30 DEG C of optimum temperatures.
The chitinase and dextranase that series bacillus is produced are cell wall degradation enzyme, thus with antibacterial activity.
Antibacterial material produced by series bacillus is mainly some polypeptides, main peptide antibiotics for polymyxins-colistin-
Circulin family, other also have circulin, jolipeptin etc..
The present invention is added in shampoo using anti-dandruff phalacrosis prevention and hair generation shampoo, enzyme and resist that series bacillus is produced
Fungus matter makes shampoo have antibacterial activity, is a kind of formula and the simple phalacrosis prevention and hair generation shampoo of manufacture method.
Merely illustrating the principles of the invention described in above-described embodiment and specification and most preferred embodiment, are not departing from this
On the premise of spirit and scope, various changes and modifications of the present invention are possible, and these changes and improvements both fall within requirement and protected
In the scope of the invention of shield.
Claims (3)
1. a kind of phalacrosis prevention and hair generation shampoo containing series bacillus, it is characterised in that：It is anti-dandruff anti-comprising 8.5-15.26 wt.%
The shampoo of hair shed and generating hair liquid, 84.74-91.5wt.%, the anti-dandruff anti-shed hair growth liquid is 1 comprising mass ratio:196-4:198
Series bacillus and acetic acid.
2. the phalacrosis prevention and hair generation shampoo containing series bacillus according to claim 1, it is characterised in that：Described hair washing
Shampoo includes 68.91-84.76 wt.% water, 10-15wt.% laureth sulfuric ester ammonium, 2-7wt.% lauroyl
Bay alcohol sulfuric ester ammonium, 1-3wt.% coconut oil diethanol amide, the 0.5-1.2wt.% of amine CAB, 1-3wt.%
Ammonium chloride, 0.5-1wt.% essence, 0.1-0.5wt.% guar hydroxypropyltrimonium chloride, 0.05-
0.15wt.% disodium EDTA, 0.03-0.07wt.% methylchloroisothiazandnone, 0.03-0.07wt.%
Methylisothiazolinone, 0.03-0.1wt.% citric acid.
3. the preparation method of the phalacrosis prevention and hair generation shampoo according to claim 2 containing series bacillus, it is characterised in that：
Including
Step one：Shampoo is prepared, preparation order is as follows：
（1）The cold water of 27.564-33.904 parts by weight is added into reaction pot, stirring is opened, high speed homogenization adds 0.1-0.5 weights
The guar hydroxypropyltrimonium chloride of part is measured, homogeneous 15min adds citric acid, the 0.05- of 0.03-0.1 parts by weight
The disodium EDTA of 0.15 parts by weight, then homogeneous 5min, after checking without clustering phenomena, begin to warm up；
（2）80~85 DEG C are heated to while stirring, stop heating；
（3）High speed homogenization is opened, laureth sulfuric ester ammonium, the 1-3 parts by weight bay alcohol sulfuric esters of 10-15 parts by weight is added
Ammonium, homogeneous stirring 30min；
（4）Shutdown disappears after most of bubble, starts to supplement the water of 27.564-33.904 parts by weight, water impact is avoided during moisturizing
Foaming；
（5）Cooling water is opened, stirring at low speed is cooled to less than 45 DEG C；
（6）Add coconut oil diethanol amide, the lauroylamidopropyl betaine of 2-7 parts by weight, the 0.5-1 of 1-3 parts by weight
Essence, the methylchloroisothiazandnone of 0.03-0.07 parts by weight, the methyl-isothiazol of 0.03-0.07 parts by weight of parts by weight
Quinoline ketone is stirred；
（7）Sample is first taken to test after the ammonium chloride of 0.5-1.2 parts by weight, the cold-water solution with 13.782-16.952 parts by weight
Add stirring 30min in pot；
Step 2：Anti-dandruff anti-shed hair growth liquid is added, concrete operations are as follows：
Shampoo is cooled to 30 ± 2 DEG C, anti-dandruff anti-shed hair growth liquid stirring is added, must not homogeneous.
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| CN201410826081.0A CN104546663B (en) | 2014-12-26 | 2014-12-26 | A kind of phalacrosis prevention and hair generation shampoo containing series bacillus |
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| CN104546663A CN104546663A (en) | 2015-04-29 |
| CN104546663B true CN104546663B (en) | 2017-08-25 |
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| CN107961212A (en) * | 2017-12-20 | 2018-04-27 | 杨新三 | A kind of oil-control antibacterial shampoo |
| CN109077989A (en) * | 2018-09-20 | 2018-12-25 | 洛娃日化(江苏)股份有限公司 | A kind of anti-dandruff shampoo of the anti-dandruff polypeptide containing biology |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009058303A2 (en) * | 2007-11-01 | 2009-05-07 | Danisco Us Inc., Genencor Division | Production of thermolysin and variants thereof and use in liquid detergents |
| CN102274473A (en) * | 2011-07-15 | 2011-12-14 | 广州市娇兰化妆品有限公司 | Compound natural plant hair loss preventing liquid and preparation method and application thereof in shampoo liquid |
| CN103732064A (en) * | 2011-05-24 | 2014-04-16 | 拜尔作物科学有限合伙公司 | Synergistic combinations of polyene fungicides and non-ribosomal peptides and related methods of use |
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2014
- 2014-12-26 CN CN201410826081.0A patent/CN104546663B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009058303A2 (en) * | 2007-11-01 | 2009-05-07 | Danisco Us Inc., Genencor Division | Production of thermolysin and variants thereof and use in liquid detergents |
| CN103732064A (en) * | 2011-05-24 | 2014-04-16 | 拜尔作物科学有限合伙公司 | Synergistic combinations of polyene fungicides and non-ribosomal peptides and related methods of use |
| CN102274473A (en) * | 2011-07-15 | 2011-12-14 | 广州市娇兰化妆品有限公司 | Compound natural plant hair loss preventing liquid and preparation method and application thereof in shampoo liquid |
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