CN104524438A - Drug for treating bedsores on clinical care - Google Patents
Drug for treating bedsores on clinical care Download PDFInfo
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- CN104524438A CN104524438A CN201410767350.0A CN201410767350A CN104524438A CN 104524438 A CN104524438 A CN 104524438A CN 201410767350 A CN201410767350 A CN 201410767350A CN 104524438 A CN104524438 A CN 104524438A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention discloses a drug for treating bedsores on clinical care and a preparation method for the drug, belonging to the field of traditional Chinese medicines. Specifically, the drug is prepared from the following raw material components in parts by weight: 1000-2400 parts of coptis chinensis, 1000-2400 parts of golden cypress, 400-1200 parts of radix angelicae, 400-1200 parts of polygonum cuspidatum, 400-800 parts of spatholobus suberctu, 400-800 parts of rhizoma sparganii, 200-600 parts of curcuma zedoary, 200-600 parts of sanguisorba officinalis, 200-600 parts of dried alum and 100-300 parts of borneol. According to the long-term clinical experiment of the inventor, the drug for treating bedsores disclosed by the invention is good in curative effect, quick in effect taking, simple in preparation process and suitable for being popularized and applied.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to medicine for the treatment of decubital ulcer and preparation method thereof in a kind of clinical care.
Background technology
Decubital ulcer, the traditional Chinese medical science is referred to as bed-sore, and be one of common clinically complication, it is that body part organizes long-term pressurized, and what disturbance of blood circulation so that local organization lost normal function and formed festers and tissue necrosis.According to incompletely statistics, the incidence rate of inpatient is 5.1%-32.1%, and easily causes infection, once deterioration can bring great misery to patient, severe patient can cause death.
Summary of the invention
The object of this invention is to provide a kind of promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing, dampness, putrefaction-removing granulation-promoting, clinical care is treated the Chinese medicine of decubital ulcer.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Clinical care is treated a medicine for decubital ulcer, the raw material making described effective ingredient consists of:
Rhizoma Coptidis, Cortex Phellodendri, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Caulis Spatholobi, Rhizoma Sparganii, Rhizoma Curcumae, Radix Sanguisorbae, dried Alumen and Borneolum Syntheticum.
Preferably, a kind of clinical care is treated the medicine of decubital ulcer, raw material composition and the parts by weight of making described effective ingredient are:
Rhizoma Coptidis 1000-2400, Cortex Phellodendri 1000-2400, Radix Angelicae Dahuricae 400-1200, Rhizoma Polygoni Cuspidati 400-1200, Caulis Spatholobi 400-800, Rhizoma Sparganii 400-800, Rhizoma Curcumae 200-600, Radix Sanguisorbae 200-600, dried Alumen 200-600 and Borneolum Syntheticum 100-300.
Best prescription, a kind of clinical care is treated the medicine of decubital ulcer, and raw material composition and the parts by weight of making described effective ingredient are:
Rhizoma Coptidis 2160, Cortex Phellodendri 1860, the Radix Angelicae Dahuricae 900, Rhizoma Polygoni Cuspidati 900, Caulis Spatholobi 600, Rhizoma Sparganii 600, Rhizoma Curcumae 300, Radix Sanguisorbae 400, dried Alumen 400 and Borneolum Syntheticum 200.
Another object of the present invention is to provide the preparation method of the medicine of a kind of clinical care being treated decubital ulcer, it is characterized in that, comprises following processing step:
(1) take Rhizoma Coptidis, Cortex Phellodendri, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Sanguisorbae, dried Alumen and Borneolum Syntheticum, co-grinding, cross 200 mesh sieves, obtain fine powder.
(2) by step 1) gained fine powder puts into pot, adds suitable Oleum Sesami, constantly stirs until medicated powder and Oleum Sesami form uniform pasty state, and be then heated to 60-80 degree Celsius and be incubated 6 hours, obtain medicine of the present invention.
Chinese medicine is thought: decubital ulcer, for suffering from, belongs to prolonged illness, deficiency of qi and blood more, and because lying in bed in prolonged illness, makes QI-blood circulation lose freely, and skin loses supports in profit, then the evil interior dye of poison, and making it blood loses meat corruption, and damp-heat blocking in the body then leads to decubital ulcer.In we, Rhizoma Coptidis, Cortex Phellodendri, heat clearing and damp drying, pathogenic fire purging is except steaming, and detoxification sore treatment is the principal agent of we; Be aided with the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, loose wind dehumidifying, understand things pain-stopping, except carbuncle is dispelled sore; Again with Caulis Spatholobi, Rhizoma Sparganii, Rhizoma Curcumae, promoting the circulation of QI to relieve pain, dredge the meridian passage; Radix Sanguisorbae, dried Alumen, cooling blood for hemostasis, removing toxic substances sore; Final with Borneolum Syntheticum, clearing away heat to alleviate pain, coordinating the actions of various ingredients in a prescription.All taste medical materials share the effect can playing promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing, dampness treatment skin ulcer, putrefaction-removing granulation-promoting altogether.
Through the clinical experiment checking that inventor is long-term, the medicine tool that the present invention treats decubital ulcer has the following advantages:
1. medicine of the present invention, good effect, instant effect.
2. drug medication of the present invention is simplified, and flavour of a drug are few, and crude drug source used is extensive, without in great shortage.
3. pharmaceutical preparation of the present invention is simple, is applicable to applying.
Clinical data
1 object
II degree of patients with bedsore 98 example selecting my institute's orthopaedics to be in hospital, is divided into two groups at random.Treatment group 49 example, man 27 example, female 22 example; Age 65-88 year.Matched group 49 example, man 25 example, female 24 example; Age 66-89 year.Wound surface size: treatment group 2.3cm × 1.9cm-10.3cm × 10.2cm; Matched group 2.0cm × 2.4cm-9.1cm × 9.9cm.There is diabetic history 25 example in two groups of cases, wherein treatment group 13 example, matched group 12 example, all adopt regular insulin treatment, and tight supervision blood glucose and glucose in urine.Two groups except Therapeutic Method, all the other every nutritional support, auxiliary treatment etc. are all identical.Two groups of sexes, age, the state of an illness, body constitution, decubital ulcer position, Area comparison, no significant difference (P > 0.05), has comparability.
2 methods
(1) treatment group: coat wound surface with medicaments uniformity prepared by best prescription of the present invention, thickness 0.5-1cm, external application carbasus immedicata is wrapped up, and every day respectively changes dressings 1 time sooner or later.
(2) matched group: with iodine tincture coating wound surface after the skin before treatment around routine disinfection decubital ulcer, local is with the coating of tobramycin 80,000 unit or use infra-red light irradiation.
Treat 10 days all continuously for two groups.
3 criterions of therapeutical effect
(1) fully recover: wound surface heals completely, clinical symptom disappearance.
(2) effective: wound surface reduces 75%, clinical symptom disappearance.
(3) take a turn for the better: wound surface reduces 25%, clinical symptoms is improved.
(4) invalid: wound surface reduces less than 25%, and clinical symptoms is without improvement.
4 experimental results
Two groups of Clinical efficacy comparisons: in table 1.
Table 1 liang group Clinical efficacy comparison
| Group | Number of cases | Recovery from illness (cure rate) | Effective | Take a turn for the better | Invalid | Total effective rate |
| Treatment group | 49 | 32(65.3％) * | 10 | 6 | 1 | 98.0％ * |
| Matched group | 49 | 16(33.7％) | 14 | 8 | 11 | 77.6％ |
Note: * compares P < 0.05 with matched group
Conclusion: experiment shows, the therapeutic outcome significant difference, particularly cure rate of two groups, medicine cure rate of the present invention is up to 65.3, and the cure rate of matched group only has 33.7 ﹪, and the total effective rate of decubital ulcer of the present invention reaches 98.0%, and matched group only has 77.6%.Illustrate that medicine of the present invention achieves better therapeutic effect than traditional therapy in curative effect, be more suitable for patients with bedsore and use.
Detailed description of the invention
Explain the present invention further below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
EXAMPLE l
Prescription (weight portion):
Rhizoma Coptidis 2160, Cortex Phellodendri 1860, the Radix Angelicae Dahuricae 900, Rhizoma Polygoni Cuspidati 900, Caulis Spatholobi 600, Rhizoma Sparganii 600, Rhizoma Curcumae 300, Radix Sanguisorbae 400, dried Alumen 400 and Borneolum Syntheticum 200.
Preparation method:
(1) take Rhizoma Coptidis, Cortex Phellodendri, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Sanguisorbae, dried Alumen and Borneolum Syntheticum, co-grinding, cross 200 mesh sieves, obtain fine powder.
(2) by step 1) gained fine powder puts into pot, adds suitable Oleum Sesami, constantly stirs until medicated powder and Oleum Sesami form uniform pasty state, and be then heated to 80 degrees Celsius and be incubated 6 hours, obtain medicine of the present invention.
Embodiment 2
Prescription (weight portion):
Rhizoma Coptidis 2000, Cortex Phellodendri 1200, the Radix Angelicae Dahuricae 800, Rhizoma Polygoni Cuspidati 600, Caulis Spatholobi 800, Rhizoma Sparganii 600, Rhizoma Curcumae 600, Radix Sanguisorbae 300, dried Alumen 600 and Borneolum Syntheticum 300.
Preparation method:
With embodiment 1
Embodiment 3
Prescription (weight portion):
Rhizoma Coptidis 1200, Cortex Phellodendri 2000, the Radix Angelicae Dahuricae 600, Rhizoma Polygoni Cuspidati 800, Caulis Spatholobi 600, Rhizoma Sparganii 500, Rhizoma Curcumae 660, Radix Sanguisorbae 360, dried Alumen 400 and Borneolum Syntheticum 100.
Preparation method:
With embodiment 1
Embodiment 4
Prescription (weight portion):
Rhizoma Coptidis 2460, Cortex Phellodendri 1800, the Radix Angelicae Dahuricae 960, Rhizoma Polygoni Cuspidati 480, Caulis Spatholobi 600, Rhizoma Sparganii 400, Rhizoma Curcumae 200, Radix Sanguisorbae 400, dried Alumen 400 and Borneolum Syntheticum 300.
Preparation method:
With embodiment 1.
Claims (4)
1. clinical care is treated a medicine for decubital ulcer, it is characterized in that, the raw material making described effective ingredient consists of:
Rhizoma Coptidis, Cortex Phellodendri, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Caulis Spatholobi, Rhizoma Sparganii, Rhizoma Curcumae, Radix Sanguisorbae, dried Alumen and Borneolum Syntheticum.
2. the medicine for the treatment of decubital ulcer according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Rhizoma Coptidis 1000-2400, Cortex Phellodendri 1000-2400, Radix Angelicae Dahuricae 400-1200, Rhizoma Polygoni Cuspidati 400-1200, Caulis Spatholobi 400-800, Rhizoma Sparganii 400-800, Rhizoma Curcumae 200-600, Radix Sanguisorbae 200-600, dried Alumen 200-600 and Borneolum Syntheticum 100-300.
3. the medicine for the treatment of decubital ulcer according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Rhizoma Coptidis 2160, Cortex Phellodendri 1860, the Radix Angelicae Dahuricae 900, Rhizoma Polygoni Cuspidati 900, Caulis Spatholobi 600, Rhizoma Sparganii 600, Rhizoma Curcumae 300, Radix Sanguisorbae 400, dried Alumen 400 and Borneolum Syntheticum 200.
4. the medicine of the treatment decubital ulcer according to claim 1-3, is characterized in that, its preparation method comprises following processing step:
(1) take Rhizoma Coptidis, Cortex Phellodendri, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Herba Schizonepetae, Rhizoma Sparganii, Rhizoma Curcumae, Radix Sanguisorbae, dried Alumen and Borneolum Syntheticum, co-grinding, cross 200 mesh sieves, obtain fine powder;
(2) by step 1) gained fine powder puts into pot, adds suitable Oleum Sesami, constantly stirs until medicated powder and Oleum Sesami form uniform pasty state, and be then heated to 60-80 degree Celsius and be incubated 6 hours.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410767350.0A CN104524438A (en) | 2014-12-12 | 2014-12-12 | Drug for treating bedsores on clinical care |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410767350.0A CN104524438A (en) | 2014-12-12 | 2014-12-12 | Drug for treating bedsores on clinical care |
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| CN104524438A true CN104524438A (en) | 2015-04-22 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535853A (en) * | 2016-01-21 | 2016-05-04 | 青岛市胶州中心医院 | Traditional Chinese medicine composition for treating bedsores for clinical nursing |
| CN105688037A (en) * | 2016-02-02 | 2016-06-22 | 姚远芳 | Traditional Chinese medicine for clinical nursing and treatment of decubitus ulcers |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058781A (en) * | 2010-12-24 | 2011-05-18 | 林栋� | Traditional Chinese medicinal film agent for treating burns and scalds |
| CN102755528A (en) * | 2011-04-24 | 2012-10-31 | 孙逊 | External Chinese medicine for treating bedsore |
| CN103948711A (en) * | 2014-05-22 | 2014-07-30 | 王清华 | Traditional Chinese medicinal ointment for treating non-healing wounds of scalds and burns |
-
2014
- 2014-12-12 CN CN201410767350.0A patent/CN104524438A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058781A (en) * | 2010-12-24 | 2011-05-18 | 林栋� | Traditional Chinese medicinal film agent for treating burns and scalds |
| CN102755528A (en) * | 2011-04-24 | 2012-10-31 | 孙逊 | External Chinese medicine for treating bedsore |
| CN103948711A (en) * | 2014-05-22 | 2014-07-30 | 王清华 | Traditional Chinese medicinal ointment for treating non-healing wounds of scalds and burns |
Non-Patent Citations (1)
| Title |
|---|
| 杜辉等: "紫草油联合红外线治疗仪治疗褥疮", 《吉林中医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535853A (en) * | 2016-01-21 | 2016-05-04 | 青岛市胶州中心医院 | Traditional Chinese medicine composition for treating bedsores for clinical nursing |
| CN105688037A (en) * | 2016-02-02 | 2016-06-22 | 姚远芳 | Traditional Chinese medicine for clinical nursing and treatment of decubitus ulcers |
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Application publication date: 20150422 |
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