CN104524336A - 一种治疗肾结石、尿路结石的中药配方 - Google Patents

一种治疗肾结石、尿路结石的中药配方 Download PDF

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CN104524336A
CN104524336A CN201410843132.0A CN201410843132A CN104524336A CN 104524336 A CN104524336 A CN 104524336A CN 201410843132 A CN201410843132 A CN 201410843132A CN 104524336 A CN104524336 A CN 104524336A
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王甡
王金红
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Qingdao Central Hospital
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Abstract

本发明公开了一种治疗肾结石、尿路结石的中药配方,由以下重量份数的中药原料配制而成:扁蓄2-4份、玉米须2-4份、鸡骨草2-4份、蝼蛄2-3份、扛板归2-3份、车前子1-3份、冬葵子2-3份、灯芯草2-4份、金沙牛1-3份、蒲黄2-4份、鸡内金1-3份、海金沙2-4份、猫须草2-3份、肉苁蓉2-3份、菟丝子2-3份、熟地黄2-3份、枸杞子2-3份、桑螵蛸2-3份、桑寄生2-3份、萆薢2-3份、泽泻2-3份、草石蚕4-6份、茯苓2-3份、薏仁2-3份和香加皮2-3份,本发明的中药配方,通过中药调理,清热解毒、利尿通淋、软坚散结、补益肝肾,有效化石、利尿排结石,利水渗湿,治疗肾结石、尿路结石,有效治疗肾结石、尿路结石,有效防止结石复发,标本兼治。

Description

一种治疗肾结石、尿路结石的中药配方
技术领域
本发明属于中医中药技术领域,特别涉及一种治疗肾结石、尿路结石的中药配方。
背景技术
肾结石、尿路结石等一直是困扰人们的常见病和多发病,其患病率约占15%,并且还有上升的趋势。已知的肾结石、尿路结石成分有数十种。临床上通常把结石分为四大类:含钙结石、感染性结石、尿酸结石和胱氨酸结石。肾结石、尿路结石的病因很多,有遗传性因素、代谢性因素、感染性因素、环境因素、饮食因素、解剖因素、药物因素等。目前治疗结石病的方法有西医疗法和中医疗法。
西医疗法如使用国外生产的消石素,难以有效推广。国内目前西医临床治疗泌尿系结石采取的是开放性手术、经皮肾镜取石术、体外超声波碎石治疗,这些方法均难以有效根治,容易造成感染,且结石复发率较高,施行手术尤其是多次手术会给人体带来诸多不利及痛苦。相对于西医疗法中存在的不足,更多患者愿意采用中医疗法。
中药已经在肾结石、尿路结石用药市场占有重要地位,因为中药副作用小,疗效确切,适用于长期用药,适应了肾结石、尿路结石容易复发的特点,临床应用非常广泛。
发明内容
本发明提供一种治疗肾结石、尿路结石的中药配方,通过中药调理,清热解毒、利尿通淋、软坚散结、补益肝肾,有效化石、利尿排结石,治疗肾结石、尿路结石,无需手术,减轻患者的痛苦。
本发明的治疗肾结石、尿路结石的中药配方,其特征在于由以下重量份数的中药原料配制而成:
扁蓄2-4份、玉米须2-4份、鸡骨草2-4份、蝼蛄2-3份、扛板归2-3份、车前子1-3份、冬葵子2-3份、灯芯草2-4份、金沙牛1-3份、蒲黄2-4份、鸡内金1-3份、海金沙2-4份、猫须草2-3份、肉苁蓉2-3份、菟丝子2-3份、熟地黄2-3份、枸杞子2-3份、桑螵蛸2-3份、桑寄生2-3份、萆薢2-3份、泽泻2-3份、草石蚕4-6份、茯苓2-3份、薏仁2-3份和香加皮2-3份。
作为优选,按如下重量份数配制:
扁蓄3份、玉米须3份、鸡骨草3份、蝼蛄2份、扛板归2份、车前子2份、冬葵子2.5份、灯芯草3份、金沙牛1份、蒲黄3份、鸡内金2份、海金沙3份、猫须草2.5份、肉苁蓉2.5份、菟丝子2.5份、熟地黄2.5份、枸杞子2.5份、桑螵蛸2.5份、桑寄生2.5份、萆薢2.5份、泽泻2.5份、草石蚕6份、茯苓3份、薏仁3份和香加皮2份。
本发明的中药,按下述步骤制备:
按照配方称取中药原料,桑螵蛸、蒲黄、鸡内金、蝼蛄研磨成粉末,其余药材加入到容器中,加水漫过药面浸泡10~20分钟,再加水没过药面3~5厘米,用武火煎煮至沸腾再改用文火煎煮20~30分钟,取滤液;然后再加水没过药面3~5厘米,用武火煎煮至沸腾再改用文火煎煮15~20分钟,然后去渣取滤液,两次滤液合并并加入研磨的桑螵蛸、蒲黄、鸡内金、蝼蛄粉末即可。
使用时,每次200~300ml,早晚各一次。
药理分析:
扁蓄:味苦,性微寒。归膀胱经。利尿通淋,杀虫,止痒。用于热淋涩痛,小便短赤,虫积腹痛,皮肤湿疹,阴痒带下等证。
玉米须:味甘性平,有利尿消肿、降血压、止血、利胆等作用。
鸡骨草:味甘微苦、性凉,归肝、胆、胃经。清热利湿,散瘀止痛。主黄疸型肝炎,胃痛,风湿骨痛,跌打瘀痛,乳痛。
蝼蛄:性味咸,寒。入胃、膀胱经。功能利水通便。可用于治疗水肿、石淋、小便不利、瘰疬、臃肿恶疮等。
扛板归:酸,平,无毒。利水消肿,清热,活血,解毒。治水肿,黄疸,泄泻,疟疾,痢疾,百日咳,淋浊,丹毒,瘰疬,湿疹,疥癣。
车前子:味甘,性寒。归肝、肾、肺、小肠经。用于热淋涩痛,水肿胀满,暑湿泄泻,目赤肿痛,痰热咳嗽。
冬葵子:甘,寒,能利水,滑肠,下乳。
灯芯草:清心降火,利尿通淋。治淋病,水肿,小便不利,湿热黄疸,心烦不寐,小儿夜啼,喉痹,创伤。
金沙牛:辛、咸,温。归肾、膀胱经。解热,镇痉,散结,利尿通淋,化疔毒。用于小儿高热,肾及尿道结石,小便不利,瘰疬,疔疮。
蒲黄:甘,平。归肝、心包经。止血,化瘀,通淋。用于吐血,衄血,咯血,崩漏,外伤出血,经闭痛经,脘腹刺痛,跌扑肿痛,血淋涩痛。
鸡内金:甘,平。归脾、胃、小肠、膀胱经;功效:消食健胃助消化,涩精止遗。可以促进胃液分泌,提高胃酸度及消化力,使胃运动功能明显增强,胃排空加快。涩精止遗。
海金沙:甘、淡,性寒;归小肠经、膀胱经。无毒。有通利小肠,疗伤寒热狂,治湿热肿毒,小便热淋膏淋血淋,石淋经痛,解热毒气。
猫须草:甘淡微苦,凉。清热去湿,排石利水。治急性肾炎,膀胱炎,尿路结石,风湿性关节炎。
菟丝子:气味辛,甘,平无毒。补肾益精,养肝明目。适用于肝肾不足的腰膝筋骨酸痛,腿脚软弱无力、阳痿遗精、呓语、小便频数、尿有余沥、头晕眼花、视物不清、耳鸣耳聋以及妇女带下、习惯性流产等症。
熟地黄:甘,微温。归肝、肾经。补血养阴,填精益髓。
枸杞:甘,平。枸杞叶:苦、甘;性凉;养肝,滋肾,润肺。枸杞叶:补虚益精,清热明目。
肉苁蓉:咸;性温;归肾;大肠经;补肾阳;益精血;润肠道。主肾阳虚衰;精血不足之阳痿;遗精;白浊;尿频余沥;腰痛脚弱;耳鸣目花;月经衍期;宫寒不孕;肠燥便秘。
桑螵蛸:咸甘,平。入肝、肾经、膀胱经;补肾助阳、固精缩尿;龙骨敛汗固精、止血涩肠。
桑寄生:味苦、甘,性平。肝、肾经。用于风湿痹痛,腰膝酸软,筋骨无力,崩漏经多,妊娠漏血,胎动不安,头晕目眩。
萆薢:味苦,性平。肾、胃经。有利湿去浊,祛风除痹的功效。
泽泻:甘,寒。主风寒湿痹,乳难,消水,养五脏,益气力,肥健。
草石蚕:和五脏,下气,清神。泡酒喝,除风破血。煮食,治溪涧砂毒。焙干吃,主治走注风,散血止痛。茎叶上的节也可捣成末和酒服。但不宜生吃或多食,否则生寸白虫。倘若与各各鱼同食,会使人呕吐。
茯苓:主治水肿尿少,痰饮眩悸,脾虚食少,便溏泄泻,心神不安,惊悸失眠。
薏仁:味甘、淡,性凉。归脾、胃、肺经。有利水渗透湿,健脾止泻,除痹,排脓,解毒散结的作用。用于水肿,脚气,小便不利,脾虚泄泻,湿痹拘挛,肺痈,肠痈;赘疣,癌肿。
香加皮:性味性温,味辛、苦;功能主治祛风湿,强筋骨。用于风寒湿痹、腰膝酸软、心悸气短、下肢浮肿。
临床试验结果如下:
(1)、一般资料
纳入标准:腰部及肾区或下腹部疼痛不适,尿频、尿急、尿痛,经肾脏B超、X线或造影确诊为肾部或尿路结石;结石直径6-10mm;肾功能正常;排除过敏体质者、妊娠或哺乳期妇女以及有严重肝肾、造血系统等疾病者。共入选50例,其中男性28例,女性21例,年龄28-55岁。
(2)、研究方法
50例入选患者分为两组,治疗组25例,对照组25例。
治疗组:服用本发明中药组合物制得的汤剂,每次200-300ml,每次两次,每天保证饮水1500ml以上。
对照组:口服五淋化石丸,一日三次,每次5粒,每天饮水1500ml以上。
(3)、疗效判定标准
痊愈:症状体征消失,肉眼见排出砂石,B超及腹平片检查肾、输尿管、膀胱正常。好转:症状体征消失,B超及腹平片检查见结石下移或变小。无效:症状体征及检查无明显改善。
(4)、研究结果
治疗30天后,两组疗效比较:
组别 例数 痊愈 好转 无效 总有效率%
治疗组 25 16 6 3 88
对照组 25 8 10 5 72
(5)、结论
治疗30天后,治疗组的总有效率为88%,高于对照组的72%(P<0.05),且治疗组的治愈率显著高于对照组的治愈率,对肾结石、尿路结石具有较好的治疗效果。服用本发明中药组合物未出现肝肾功能损害等不良反应,表明本发明中药组合物具有较好的安全性。
考虑结石乃与肾相关的疾病,肾虚水液气化失司乃结石形成的主因,故在溶石、排石、软坚、消积,攻其有形病邪的同时辅以补肾固本,以策万全。本发明配方中,选用鸡内金、海金沙、猫须草作为化石要药,辅以扁蓄、玉米须、鸡骨草、蝼蛄、扛板归、车前子、冬葵子、灯芯草等多味利尿通淋药,有效化石排石;泽泻、茯苓、草石蚕、薏仁、香加皮利水渗湿,用以排除结石阻塞后的积水,排除肾湿,防止复发;肉苁蓉、菟丝子、熟地、枸杞子、桑螵蛸、桑寄生、萆薢,补益肝肾、强肾健骨,以防止泄下太过;诸药相伍,共奏软坚散结、化石、利尿排石,利水渗湿,有效治疗肾结石、尿路结石,有效防止结石复发,标本兼治。
具体实施方式
实施例1
白茅根3份、玉米须3份、鸡骨草3份、龙骨2份、金钱草2份、车前子2份、冬葵子2份、灯芯草3份、金沙牛2份、蒲黄3份、鸡内金2份、海金沙3份、猫须草3份、肉苁蓉2份、菟丝子2份、熟地黄3份、枸杞子3份、桑螵蛸3份、桑寄生2份、萆薢3份、厚朴5份、陈皮2份、薤白3份、大腹皮3份、泽泻5份和茯苓5份。
本发明的中药配方,按下述方法制备和使用:
按照配方称取中药原料,桑螵蛸、蒲黄、鸡内金、蝼蛄研磨成粉末,其余药材加入到容器中,加水漫过药面浸泡15分钟,再加水没过药面4厘米,用武火煎煮至沸腾再改用文火煎煮30分钟,取滤液;然后再加水没过药面4厘米,用武火煎煮至沸腾再改用文火煎煮20分钟,然后去渣取滤液,两次滤液合并并加入研磨的桑螵蛸、蒲黄、鸡内金、蝼蛄粉末即可。
使用时,每次250ml,早晚各一次。

Claims (2)

1.一种治疗肾结石、尿路结石的中药配方,其特征在于由以下重量份数的中药原料配制而成:扁蓄2-4份、玉米须2-4份、鸡骨草2-4份、蝼蛄2-3份、扛板归2-3份、车前子1-3份、冬葵子2-3份、灯芯草2-4份、金沙牛1-3份、蒲黄2-4份、鸡内金1-3份、海金沙2-4份、猫须草2-3份、肉苁蓉2-3份、菟丝子2-3份、熟地黄2-3份、枸杞子2-3份、桑螵蛸2-3份、桑寄生2-3份、萆薢2-3份、泽泻2-3份、草石蚕4-6份、茯苓2-3份、薏仁2-3份和香加皮2-3份。
2.根据权利要求1所述的治疗肾结石、尿路结石的中药配方,其特征在于由以下重量份数的中药原料配制而成:扁蓄3份、玉米须3份、鸡骨草3份、蝼蛄2份、扛板归2份、车前子2份、冬葵子2.5份、灯芯草3份、金沙牛1份、蒲黄3份、鸡内金2份、海金沙3份、猫须草2.5份、肉苁蓉2.5份、菟丝子2.5份、熟地黄2.5份、枸杞子2.5份、桑螵蛸2.5份、桑寄生2.5份、萆薢2.5份、泽泻2.5份、草石蚕6份、茯苓3份、薏仁3份和香加皮2份。
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Publication number Priority date Publication date Assignee Title
CN105148050A (zh) * 2015-07-25 2015-12-16 王军 一种治疗肾结石的中药组合物
CN107029141A (zh) * 2017-06-16 2017-08-11 黄建明 一种肾劳排石散及其制备方法

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Publication number Priority date Publication date Assignee Title
CN103705797A (zh) * 2013-12-17 2014-04-09 陈中元 一种治疗肾结石的药物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103705797A (zh) * 2013-12-17 2014-04-09 陈中元 一种治疗肾结石的药物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105148050A (zh) * 2015-07-25 2015-12-16 王军 一种治疗肾结石的中药组合物
CN107029141A (zh) * 2017-06-16 2017-08-11 黄建明 一种肾劳排石散及其制备方法

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