CN104524153B - A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome - Google Patents
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, the Chinese medicine composition is made up of following bulk drug：Dried human placenta, teasel root, semen astragali complanati, eclipta, asparagus fern, Paper mulberry Fruit, semen litchi, rose, spina date seed, valerian, Herba Lycopi, amber, earthworm.The Chinese medicine composition for the treatment of climacteric Female Urethral Syndrome provided by the invention, combined according to analysis of the traditional Chinese medicine to climacteric Female Urethral Syndrome syndrome characteristics, and with reference to modern medicine study achievement.Have the advantages that curative effect is stable, adverse reaction is few, easy to use, patient compliance is high.36 patients are treated using the Chinese medicine composition water decoction for the treatment of climacteric Female Urethral Syndrome provided by the invention, treated through 2 weeks, cure 26, take a turn for the better 7, invalid 3, total effective rate 91.7%.
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, more particularly to a kind of Chinese medicine group for treating climacteric Female Urethral Syndrome
Compound.
Background technology
Female Urethral Syndrome refers to have lower urinary tract to stimulate disease to include frequent micturition, urgent urination, odynuria, lower abdomen falling inflation, dysuria,
And without bladder, urethra organic disease and obvious bacteruria.It is comprehensive to belong to this by about 40% ~ 50% patient in the women for having urinary tract infection symptom
Simulator sickness, this sick pathogenic factor are not yet fully apparent from present, may decline with urethra anterior sphincter spasm, women estrogen level,
Allergy or chemically excitation, mental element, neural factors etc. are relevant.The incretion balance state of perimenopausal women becomes
Change, cause the functional disturbance of automatic nervous system so as to produce the clinical symptoms of different degrees of vegetative nerve functional disturbance.By
Decline in ovarian function, internal estrogen secretion imbalance, the function of organizations such as neck of urinary bladder, urethra can be caused to change, so as to go out
Now urinary tract infection symptom.Meanwhile pain caused by long-term urethral stimulant symptom also easily induces the disposition change of women, women
The emotional handicaps such as urethral syndrome patient's generally existing depression and anxiety, have a strong impact on the quality of life of patient.Clinical treatment at present
Climacteric Female Urethral Syndrome is more to be forced with complementing estrogen, calmness, antianxiety, improvement vegetative nerve function, coordination bladder
Urinate based on incoordination of flesh and urethra anterior sphincter etc., but curative effect is difficult fully up to expectations, and side effect is more, patient compliance
Difference.
It facts have proved that Chinese medicine urinary system has good therapeutic effect, but specific method or folk prescription plus-minus or treatment by typing,
Its curative effect is how, is heavily dependent on the height of doctor's professional skill, and goes to a doctor repeatedly, and inconvenience is brought to patient,
And cause the significant wastage of social resources.Therefore, need the physiological and pathological feature according to climacteric women badly, it is steady to develop curative effect
The special-purpose medicaments for the treatment of climacteric Female Urethral Syndrome fixed, adverse reaction is few, easy to use, patient compliance is high.
The content of the invention
It is an object of the invention to overcome in the prior art without the compatibility conjunction for climacteric Female Urethral Syndrome
The Chinese medicine composition of reason deficiency and put forward, that is, a kind of Chinese traditional medicine composition for treating climacteric Female Urethral Syndrome is provided
Thing.
In order to realize foregoing invention purpose, the invention provides following technical scheme：
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, is made up of the bulk drug of following mass ratio
Medicament：
2~4 parts of dried human placenta, 9~15 parts of teasel root, 10~20 parts of semen astragali complanati, 6~12 parts of eclipta, 6~12 parts of asparagus fern, paper mulberry
Real 6~10 parts of son, 6~10 parts of semen litchi, 4~8 parts of rose, 9~15 parts of spina date seed, 4~6 parts of valerian, 10~20 parts of Herba Lycopi,
1~3 part of amber, 1~3 part of earthworm.
The pharmacological action of bulk drug of the present invention is as follows：
Dried human placenta：It is sweet, salty, warm, return lung, liver and kidney channel.Tonifying kidney and benefiting sperm, nourishing blood and invigorating qi.Dried human placenta, which has, promotes mammary gland and women
The function of reproductive development, the metabolism of estrogen and progesterone is participated in, influence the menstrual cycle, strengthen Abwehrkraft des Koepers, tool is exempted from
Epidemic disease and anti-allergic effects.
Teasel root：Bitter, pungent, tepor, returns liver and kidney channel.Tonify the liver and kidney, strengthening the muscles and bones, promoting blood circulation is cured the wound.Teasel root has antivitamin E
The effect of deficiency disease, there are apocenosis, hemostasis, analgesia, promotion organization palingenesis to sore, the life in ovariectomized mouse uterus can be promoted
Long development.
Semen astragali complanati：It is sweet, warm, return liver and kidney channel.Invigorate the kidney and stop nocturnal emission, nourish the liver to improve visual acuity.Semen astragali complanati has antifatigue effect, is also depressured
Effect and obvious reduction serum cholesterol, triglycerides and the effect for increasing cerebral blood flow (CBF), and hemorheology index can be improved.
Eclipta：It is sweet, sour, cold, return liver and kidney channel.It is nourishing liver and kidney, cooling blood and hemostasis.Eclipta has raising body non-specific
Property immunologic function effect, oxygen radical can be eliminated to suppress 5- lipoxygenase, protect chromosome, liver protection, promote liver cell again
It is raw, increase coronary blood flow, extend life of the mouse under normobaric hypoxia, improve depositing in the case of hypobaric hypoxia mouse
Motility rate；And there is calmness, ease pain, promote hair growth, act on hair blackening, hemostasis, antibacterial, anti-Amoeba, anticancer etc..
Asparagus fern：It is sweet, bitter, cold, return lung, kidney, stomach.Nourishing yin to moisten dryness, clearing lung-heat are promoted the production of body fluid.Asparagus fern has certain antiasthmatic effect eliminating the phlegm to make
With；Peripheral vascular expansion, drop in blood pressure, contractile force enhancing, decreased heart rate and urine volume increase can be made；It is thin in vain with rise periphery
Born of the same parents, strengthen the effect of reticuloendothelial system phagocytic activity and humoral immune function；Antibody tormation can be promoted, when extending antibody existence
Between.
Paper mulberry Fruit：It is sweet, cold, return liver and kidney channel.Nourshing kidney, clear liver, improving eyesight, diuresis.Paper mulberry Fruit has promotion to remember, enhancing is immune,
Antibacterial, reducing blood lipid, antioxidation.
Semen litchi：Pungent, slight bitter, temperature, Return liver, stomach.Promoting the circulation of qi dissipating bind, eliminating cold to stop pain.Semen litchi have hypoglycemic, Adjust-blood lipid and
Antioxidation, T-CHOL can be reduced（TC）And triglycerides（TG）；The radical damage caused by ALX can be resisted, is improved anti-
Oxidizing ferment SOD activity；There is the mutagenesis of confrontation salmonella typhimurium；There is suppression to make to hepatitis b virus s antigen
With.
Rose：Sweet, slight bitter, temperature, Return liver, the spleen channel.Soothing liver-qi stagnation, promoting blood circulation and stopping pain.Rose, which has, promotes choleresis to make
With；There is certain protective effect to experimental animal models myocardial ischemia.
Spina date seed：It is sweet, sour, flat, the thoughts of returning home, liver, gallbladder channel.Nourishing heart benefit liver, calms the nerves, arrest sweating.Spina date seed have tranquilizing soporific and
Antiarrhythmic effect, and the central inhibitory action of barbiturate can be cooperateed with；Also anticonvulsion, analgesia, body-temp. reducing, decompression
Effect；In addition, spina date seed also has reducing blood lipid, anti anoxia, antitumor, suppression platelet aggregation, strengthen immunologic function and excited son
Palace acts on.
Valerian：It is pungent, sweet, warm, the thoughts of returning home, Liver Channel.Calm the nerves qi-regulating, promoting blood circulation and stopping pain.Valerian has tranquilizing effect, can substantially expand
Coronary artery blood vessel is opened, improves myocardial ischemia, reduces myocardial oxygen consumption, anti-arrhythmia.
Herba Lycopi：Bitter, pungent, tepor, Return liver, the spleen channel.Promoting blood circulation for regulating menstruation, dissolving stasis disappear carbuncle, inducing diuresis for removing edema.Herba Lycopi's water decoction can resist
Ex vivo thrombosis, play the role of slightly to suppress blood coagulation system and enhancing fibrinolytic；Herb preparation has cardiotonic.
Amber：It is sweet, flat, the thoughts of returning home, liver, bladder warp.Tranquillizing the mind by relieving convulsion, promoting blood circulation to remove blood stasis, inducing diuresis for treating strangurtia.Amber has CNS inhibition
Effect, mouse autonomic activities can be significantly reduced, extend the length of one's sleep of yellow Jackets, and to big white mouse audiogenic convulsion with
The reaction of small white mouse electroconvulsive shock has protective effect, can extend its time of occurrence to being fainted from fear caused by picrotoxin, strychnine, semicarbazides.
Earthworm：It is salty, cold, Return liver, spleen, bladder warp.Heat-clearing is calmed the frightened, and dredging collateral, is relievingd asthma, diuresis.Earthworm has antipyretic, calm, anti-
Convulsions, diastole bronchus, decompression, anticoagulation；Also having, which strengthens immune, antitumor, antibacterial, diuresis, excited uterus and intestines, puts down
Sliding flesh effect.
Modern medicine believes that, climacteric women has significantly due to the estrogen level Female Urethral Syndrome that changes
Feature, its lower urinary tract irritation is more obvious, while with obvious anxiety symptom.And estrogen has vasodilator, improve
Ringing, urethral mucosa and sub-mucosal tissues plumpness can be made and keep flexibility, and antidepressant effect.
Climacteric Female Urethral Syndrome belongs to the traditional Chinese medical science " stranguria " category.Because the course of disease is longer, patient nearly all has not
With the medical history invalid using antibiosis extract for treating of degree.The interpretation of the cause, onset and process of an illness of climacteric Female Urethral Syndrome and general stranguria is damp and hot accumulates
Forge that burnt, functioning of bladder is unfavorable different.The traditional Chinese medical science think " Zhu Linzhe, by kidney deficiency wing moon bright heat therefore.... kidney deficiency then urine
Number, wing moon bright heat is then underwater puckery, several and puckery, then leaching drip is not declared, therefore the leaching of meaning ".Therefore the kidney deficiency of the normal duty of this disease.And climacteric
Women is in special physiological period, covers the phase of married woman seventy-seven, and kidney qi degradation, " menses " will exhaust, and rushes conception vessel void, and kidney loses gasification, wing
Guang folding is forfeited one's integrity and suffers from this disease.And " the woman is based on the liver ", liver happiness bar reach and dislike depression；" heart is the head of internal organs, Zong Tonghun
Soul, and the will ", its feelings will change the dirty in conscience two of more duties.In summary, the climacteric Female Urethral Syndrome interpretation of the cause, onset and process of an illness is
Asthenia of renal qi, stagnation of QI due to depression of the liver, heart arteries and veins stasis blocking.The present invention uses the tangible product of dried human placenta flesh and blood to fill out kidney essense；Teasel root, semen astragali complanati temperature
Filling liver kidney, astringent sperm contracting urine；Eclipta, asparagus fern, Paper mulberry Fruit are nourishing liver and kidney；Semen litchi, rose soothing liver-qi stagnation；Spina date seed, valerian
Mental-tranquilization, vital energy regualting and blood circulation-promoting；Herba Lycopi, amber, earthworm promoting blood circulation to remove blood stasis, inducing diuresis for treating strangurtia.All medicine compatibilities, play liver-kidney tonifying altogether, soothing the liver
Xie Yu, mental-tranquilization, the effect of Huayu Tonglin.Modern study shows that kidney-nourishing tcm drug has estrogen-like action, and can adjust and force urine
Muscular function and sphincter vesicae folding.
Preferably, it is described treatment climacteric Female Urethral Syndrome Chinese medicine composition by following mass ratio raw material
Medicament made of medicine：
2~4 parts of dried human placenta, 11~13 parts of teasel root, 13~17 parts of semen astragali complanati, 8~10 parts of eclipta, 8~10 parts of asparagus fern, paper mulberry
Real 7~9 parts of son, 7~9 parts of semen litchi, 5~7 parts of rose, 11~13 parts of spina date seed, 4~6 parts of valerian, 13~17 parts of Herba Lycopi,
1~3 part of amber, 1~3 part of earthworm.
It is further preferred that the Chinese medicine composition of the treatment climacteric Female Urethral Syndrome is by following mass ratio
Bulk drug made of medicament：
3 parts of dried human placenta, 12 parts of teasel root, 15 parts of semen astragali complanati, 9 parts of eclipta, 9 parts of asparagus fern, 8 parts of Paper mulberry Fruit, 8 parts of semen litchi,
6 parts of rose, 12 parts of spina date seed, 5 parts of valerian, 15 parts of Herba Lycopi, 2 parts of amber, 2 parts of earthworm.
The Chinese medicine composition of the treatment climacteric Female Urethral Syndrome can use existing Chinese medicine preparation technique system
It is standby such as said components to be obtained water decoction using decocting into any conventional oral preparations, can also be by other existing
The Chinese medicine composition of the treatment climacteric Female Urethral Syndrome is prepared piece agent, water-honeyed pill, glue by Chinese medicine preparation technology
Wafer, powder, paste, oral liquid, granule.
Compared with prior art, beneficial effects of the present invention
The Chinese medicine composition for the treatment of climacteric Female Urethral Syndrome provided by the invention, is to enclosing absolutely according to traditional Chinese medicine
The analysis of menstruating women urethral syndrome syndrome characteristics, and combined with reference to modern medicine study achievement.Stablize with curative effect,
The advantages that adverse reaction is few, easy to use, patient compliance is high.
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, clinical efficacy are summarized
1 general information
36 patients, 40 ~ 57 years old age, average age（47.5±8.3）Year；The course of disease 3 months ~ 6 years, average course of disease（2.8
±0.5）Year.
2 case inclusive criterias
1. meet《Modern urinary surgery》（Feng Teng gallop modern times urinary surgery Tianjin：Tianjin science tech publishing house,
2000：423）Middle Female Urethral Syndrome diagnostic criteria：With diseases such as discomforts on frequent micturition, urgent urination, odynuria, dysuria, pubis
Shape；Multiple routine urianlysis is normal, and clean the middle urine culture bacterium colony counts<105/ml；Without heating, blood leukocytes rise etc..②
Patient is climacteric women.
3 treatment methods
Dried human placenta（Grind and take after mixing it with water）3 grams, 12 grams of teasel root, 15 grams of semen astragali complanati, 9 grams of eclipta, 9 grams of asparagus fern, 8 grams of Paper mulberry Fruit,
8 grams of semen litchi, 6 grams of rose, 12 grams of spina date seed, 5 grams of valerian, 15 grams of Herba Lycopi, amber（Grind and take after mixing it with water）2 grams, earthworm（Grind punching
Clothes）2 grams, water decoction is made according to conventional Chinese medicine preparation technology, everyone one portion per day.
4 treatment results
4.1 criterion of therapeutical effect：1. cure：Frequent micturition, urgent urination, odynuria symptom disappear.2. take a turn for the better：Frequent micturition, urgent urination, odynuria symptom
Compared with mitigating before treatment.It is 3. invalid：Frequent micturition, urgent urination, odynuria symptom are without change.
4.2 result：Treated through 2 weeks, cure 26, taken a turn for the better 7, invalid 3, total effective rate 91.7%.
Embodiment
With reference to embodiment, the present invention is described in further detail.But this should not be interpreted as to the present invention
The scope of above-mentioned theme is only limitted to following embodiment, all models that the present invention is belonged to based on the technology that present invention is realized
Enclose.
Embodiment 1
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, is by dried human placenta（Grind and take after mixing it with water）4 grams, it is continuous
Disconnected 15 grams, 20 grams of semen astragali complanati, 12 grams of eclipta, 12 grams of asparagus fern, 10 grams of Paper mulberry Fruit, 10 grams of semen litchi, 8 grams of rose, spina date seed
15 grams, 6 grams of valerian, 20 grams of Herba Lycopi, amber（Grind and take after mixing it with water）3 grams, earthworm（Grind and take after mixing it with water）3 grams, according to conventional Chinese medicine preparation skill
Water decoction is made in art, everyone one portion per day.
Embodiment 2
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, is by dried human placenta（Grind and take after mixing it with water）4 grams, it is continuous
Disconnected 13 grams, 17 grams of semen astragali complanati, 10 grams of eclipta, 10 grams of asparagus fern, 9 grams of Paper mulberry Fruit, 9 grams of semen litchi, 7 grams of rose, spina date seed 13
Gram, 6 grams of valerian, 17 grams of Herba Lycopi, amber（Grind and take after mixing it with water）3 grams, earthworm（Grind and take after mixing it with water）3 grams, according to conventional Chinese medicine preparation technology
Water decoction is made, everyone one portion per day.
Embodiment 3
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, is by dried human placenta（Grind and take after mixing it with water）3 grams, it is continuous
Disconnected 12 grams, 15 grams of semen astragali complanati, 9 grams of eclipta, 9 grams of asparagus fern, 8 grams of Paper mulberry Fruit, 8 grams of semen litchi, 6 grams of rose, 12 grams of spina date seed,
5 grams of valerian, 15 grams of Herba Lycopi, amber（Grind and take after mixing it with water）2 grams, earthworm（Grind and take after mixing it with water）2 grams, it is made according to conventional Chinese medicine preparation technology
Water decoction, everyone one portion per day.
Embodiment 4
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, is by dried human placenta（Grind and take after mixing it with water）2 grams, it is continuous
Disconnected 11 grams, 13 grams of semen astragali complanati, 8 grams of eclipta, 8 grams of asparagus fern, 7 grams of Paper mulberry Fruit, 7 grams of semen litchi, 5 grams of rose, 11 grams of spina date seed,
4 grams of valerian, 13 grams of Herba Lycopi, amber（Grind and take after mixing it with water）1 gram, earthworm（Grind and take after mixing it with water）1 gram, it is made according to conventional Chinese medicine preparation technology
Water decoction, everyone one portion per day.
Embodiment 5
A kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, is by dried human placenta（Grind and take after mixing it with water）2 grams, it is continuous
Disconnected 9 grams, 10 grams of semen astragali complanati, 6 grams of eclipta, 6 grams of asparagus fern, 6 grams of Paper mulberry Fruit, 6 grams of semen litchi, 4 grams of rose, 9 grams of spina date seed, figured silk fabrics
4 grams of grass, 10 grams of Herba Lycopi, amber（Grind and take after mixing it with water）1 gram, earthworm（Grind and take after mixing it with water）1 gram, water is made according to conventional Chinese medicine preparation technology
Decoction, everyone one portion per day.
Claims (3)
1. a kind of Chinese medicine composition for treating climacteric Female Urethral Syndrome, it is characterised in that by the original of following mass ratio
Expect medicament made of medicine：
2~4 parts of dried human placenta, 9~15 parts of teasel root, 10~20 parts of semen astragali complanati, 6~12 parts of eclipta, 6~12 parts of asparagus fern, Paper mulberry Fruit 6
~10 parts, 6~10 parts of semen litchi, 4~8 parts of rose, 9~15 parts of spina date seed, 4~6 parts of valerian, 10~20 parts of Herba Lycopi, amber 1
~3 parts, 1~3 part of earthworm.
2. as claimed in claim 1 treatment climacteric Female Urethral Syndrome Chinese medicine composition, it is characterised in that by with
Medicament made of the bulk drug of lower mass ratio：
2~4 parts of dried human placenta, 11~13 parts of teasel root, 13~17 parts of semen astragali complanati, 8~10 parts of eclipta, 8~10 parts of asparagus fern, Paper mulberry Fruit
7~9 parts, 7~9 parts of semen litchi, 5~7 parts of rose, 11~13 parts of spina date seed, 4~6 parts of valerian, 13~17 parts of Herba Lycopi, amber 1
~3 parts, 1~3 part of earthworm.
3. as claimed in claim 1 treatment climacteric Female Urethral Syndrome Chinese medicine composition, it is characterised in that by with
Medicament made of the bulk drug of lower mass ratio：
3 parts of dried human placenta, 12 parts of teasel root, 15 parts of semen astragali complanati, 9 parts of eclipta, 9 parts of asparagus fern, 8 parts of Paper mulberry Fruit, 8 parts of semen litchi, rose
Spend 6 parts, 12 parts of spina date seed, 5 parts of valerian, 15 parts of Herba Lycopi, 2 parts of amber, 2 parts of earthworm.
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| CN105943591A (en) * | 2016-06-08 | 2016-09-21 | 河南中医学院 | Application of fenugreek total flavones to preparation of medicine for treating perimenopausal syndromes |
| CN105998145A (en) * | 2016-06-08 | 2016-10-12 | 河南中医学院 | Application of cortex eucommiae total flavonoids to preparation of medicine for treating perimenopausal syndrome |
| CN105998160A (en) * | 2016-06-08 | 2016-10-12 | 河南中医学院 | Application of flavonoids of astragali complanali to preparation of drugs for treating perimenopausal depression |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101314004A (en) * | 2007-05-29 | 2008-12-03 | 北京羚锐伟业科技有限公司 | Medicament for treating gynaecologic urinary system infection contamination and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101314004A (en) * | 2007-05-29 | 2008-12-03 | 北京羚锐伟业科技有限公司 | Medicament for treating gynaecologic urinary system infection contamination and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 尿道综合征辨治五法;朱冬云;《湖北中医杂志》;20001231;第22卷(第7期);第28页 * |
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Inventor after: Qu Xiuping Inventor after: Sun Guoliang Inventor after: Sun Tao Inventor before: Han Ruilan Inventor before: Jiang Chunhua |
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Effective date of registration: 20171117 Address after: 261400 Laizhou City Maternal and child health care hospital, Yantai, Laizhou City, Yantai, Shandong Applicant after: Qu Xiuping Applicant after: Sun Guoliang Applicant after: Sun Tao Address before: 262500 Shandong city of Weifang province Qingzhou city yunmenshan Road No. 9966 Weifang nursing Career Academy Applicant before: Han Ruilan |
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