CN104524151B - 一种山茶油中药去灰指甲油 - Google Patents

一种山茶油中药去灰指甲油 Download PDF

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CN104524151B
CN104524151B CN201510042734.0A CN201510042734A CN104524151B CN 104524151 B CN104524151 B CN 104524151B CN 201510042734 A CN201510042734 A CN 201510042734A CN 104524151 B CN104524151 B CN 104524151B
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蔡之伟
李汉昌
姚小华
周伯川
陈黑龙
刘春雷
蔡青梅
蔡春辉
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FUJIAN CHUNHUI BIOLOGICAL ENGINEERING Co Ltd
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Abstract

一种山茶油中药去灰指甲油，按原料重量分数进行制备：山油茶15‑25份、花椒5‑10份、青蒿5‑10份­­­­­­­­­­、荜澄茄5‑10份、肉桂5‑10份、补骨脂5‑10份、没药3‑6份、知母3‑6份、茵陈3‑6份、苍耳子3‑6份、厚朴3‑6份。山茶油能够很好抑制真菌的生长、促进指甲的修复并促进其他成分被指甲及皮肤的吸收，花椒、青蒿、荜澄茄、肉桂对真菌有很好的抑制杀灭作用，补骨脂对致甲癣真菌有很好的抑制作用，没药、知母、茵陈、苍耳子、厚朴等对多种皮肤真菌有不同程度的抑制作用。其使用能够达到强效杀菌、抑制复发并修复指甲，同时本品也可以对常见皮肤真菌达到一定的抑制和灭杀效果，基本为天然、植物原料具很高的安全性。

Description

一种山茶油中药去灰指甲油
技术领域
本发明涉及一种山茶油中药去灰指甲油，特别是以山茶油和中草药为主要原材料的去灰指甲及治疗其他致皮肤病真菌的制备方法。
背景技术
自然界当中的真菌种类繁多，有些真菌还具有致病性，特别是让人们的皮肤出现各种各样的疾病，例如甲癣，俗称“灰指甲”就是其中较为严重的一种，是由皮癣菌、酵母菌及非皮癣菌等真菌引起的指甲感染，该皮肤病具有传染性、复发性等特征，给人们带来很多困扰。目前对灰指甲的治疗主要为化学方法例如咪唑类抗真菌、酮康唑霜等，存在一定的安全使用隐患。我国有着丰富的野茶油和中草药的资源，利用这些资源来治疗灰指甲为一种安全的治疗方法。
发明内容
本发明的目的是以山茶油、花椒、青蒿、荜澄茄、肉桂、补骨脂、没药、知母、茵陈、苍耳子、厚朴等植物性原料开发成一种山茶油中药去灰指甲油。由多种对不同皮肤致病真菌有抑制和灭杀作用的原料组成，原料均为中草药和具有很好的促渗作用的山茶油，对于灰指甲为一种安全性很高的治疗方法。
为实现上述目的，本发明采用如下技术方案：
一种山茶油中药去灰指甲油，其配方的原料组分按重量份数组成为：山茶油15-25份、花椒5-10份、青蒿5-10份、荜澄茄5-10份、肉桂5-10份、补骨脂5-10份、没药3-6份、知母3-6份、茵陈3-6份、苍耳子3-6份、厚朴3-6份。
一种山茶油中药去灰指甲油制备方法：1）采用干燥的花椒、青蒿、没药、知母、茵陈、苍耳子、厚朴并进行粉碎在10-40目之间，分别在100度热水中浸提45分钟，过滤备用，料液比为1:6 ；肉桂、荜澄茄挥发油按原料比例分别采用挥发油提取器进行制备；补骨脂采用6倍质量的70%乙醇浸提1周，过滤；
2）在山茶油中分别加入花椒、青蒿、没药、知母、茵陈、苍耳子、厚朴、补骨脂中药浸提液进充分混匀，再加入无水乙醇至产品重量分数达到99份使产品的油相与水相充分融合不易分层，最后加入肉桂、荜澄茄挥发性油充分混匀并将产品进行保存。
本发明所述的对皮肤致病真菌有一定的抑制和灭杀作用的中药组合物中：山茶油含有黄酮类、脂肪类（主要有油酸、亚油酸、棕榈酸等，还含有角鲨烯、甾醇、茶多酚等成分）、糖类等成分，是很好的渗透促进剂能促进皮肤很好的吸收其他营养成分并对真菌的生长有高度的抑制作用；肉桂含有挥发油、萜类及其糖苷、黄烷醇及其多聚体、生物碱类等成分，其中桂醛具有很强的杀菌作用，尤其是对皮肤癣菌的作用；苍耳子：含有挥发油、脂肪油、黄质宁、氯丁醇等成分，其中黄质宁、黄质敏等成分有抗真菌作用；花椒：含有挥发油、生物碱及酰胺类、苯丙素类谷甾醇及有机酸等成分，具有抗细菌的作用，同时其挥发油对某些致病真菌有杀菌作用；没药含有挥发油、树脂等成分，对皮肤真菌有不同程度的抑制作用；补骨脂含有呋喃香豆素、黄酮类、脂肪类等成分，其中脂溶性成分起到很强的抑菌作用；青蒿只要成分有倍半萜类、黄酮类、香豆素类、挥发性成分等，其中挥发油可以抑制和杀灭所有皮肤癣菌；知母含有大量甾体皂甙、木质素类、双苯吡酮类、多糖类、有机酸类及微量元素，对常见致病性皮肤癣菌有较强的抑制作用；茵陈含有香豆素类、色原酮类、黄酮类、香豆酸及其他有机酸类、挥发油、醛酮化合物、呋喃类等成分，具有抗细菌和真菌的作用；厚朴含有酚性、生物碱、芥子醛、挥发油性成分等，具抗细菌真菌作用。
本发明的优点在于：本发明是从中草药中筛选得到对不同皮肤真菌有不同程度的抑制及杀灭作用，对致甲癣真菌达到强效杀菌、抑制复发并达到修复指甲，同时本去灰甲油也可以对常见皮肤真菌达到抑制和灭杀效果。
具体实施方式
实施例1
1、称取花椒8份、青蒿8份、荜澄茄8份、肉桂8份、补骨脂8份、没药5份、知母5份、茵陈5份、苍耳子5份、厚朴5份。其中没药、知母、厚朴、青蒿、茵陈、花椒各用6倍质量的蒸馏水进行100度浸提45分钟，过滤备用；肉桂、荜澄茄挥发油采用挥发油提取器进行制备；补骨脂用6倍质量的70%乙醇进行浸泡一周过滤。
2、在25份的山茶油中分别加入不同中药浸提液花椒8份、青蒿8份、没药5份、知母5份、茵陈5份、苍耳子5份、厚朴5份、补骨脂8份进充分混匀，再加入无水乙醇至产品重量分数达到99份使产品的油相与水相充分融合不易分层，最后加入肉桂、荜澄茄挥发性油充分混匀并将产品进行保存。
实施例2
1、取花椒10份、青蒿10份、荜澄茄10份、肉桂10份、补骨脂10份、没药5份、知母5份、茵陈5份、苍耳子5份、厚朴5份。其中没药、知母、厚朴、青蒿、茵陈、花椒各用6倍质量的蒸馏水进行100度浸提45分钟，过滤备用；肉桂、荜澄茄挥发油采用挥发油提取器进行制备；补骨脂用6倍质量的70%乙醇进行浸泡一周过滤。
2、现在25份的山茶油中分别加入不同中药浸提液花椒10份、青蒿10份、没药5份、知母5份、茵陈5份、苍耳子5份、厚朴5份、补骨脂10份进充分混匀，再加入无水乙醇至产品重量分数达到99份使产品的油相与水相充分融合不易分层，最后加入肉桂、荜澄茄挥发性油充分混匀并将产品进行保存。
实施例3
1、取花椒10份、青蒿10份、荜澄茄10份、肉桂10份、补骨脂10份、没药3份、知母3份、茵陈3份、苍耳子3份、厚朴3份。其中没药、知母、厚朴、青蒿、茵陈、花椒各用6倍质量的蒸馏水进行100度浸提45分钟，过滤备用；肉桂、荜澄茄挥发油采用挥发油提取器进行制备；补骨脂用6倍质量的70%乙醇进行浸泡一周过滤。
2、在25份的山茶油中分别加入不同中药浸提液花椒10份、青蒿10份、没药3份、知母3份、茵陈3份、苍耳子3份、厚朴3份、补骨脂10份进充分混匀，再加入无水乙醇至产品重量分数达到99份使产品的油相与水相充分融合不易分层，最后加入肉桂、荜澄茄挥发性油充分混匀并将产品进行保存。
实施例4
1、称取花椒10份、青蒿10份、荜澄茄10份、肉桂10份、补骨脂10份、没药3份、知母3份、茵陈3份、苍耳子3份、厚朴3份。其中没药、知母、厚朴、青蒿、茵陈、花椒各用6倍质量的蒸馏水进行100度浸提45分钟，过滤备用；肉桂、荜澄茄挥发油采用挥发油提取器进行制备；补骨脂用6倍质量的70%乙醇进行浸泡一周过滤。
2、在20份的山茶油中分别加入不同中药浸提液花椒10份、青蒿10份、没药3份、知母3份、茵陈3份、苍耳子3份、厚朴3份、补骨脂10份进充分混匀，再加入无水乙醇至产品重量分数达到99份使产品的油相与水相充分融合不易分层，最后加入肉桂、荜澄茄挥发性油充分混匀并将产品进行保存。
本发明，曾进行以下试验：
山茶油中药去灰甲油在培养皿内对某些致病性真菌有抑制和杀灭作用。实验分为五组，即对照组和有四种方案做制成的山茶油中药去灰甲油，对照组为无菌水，培养基为改良沙氏葡萄糖琼脂，选用红色毛癣菌、须癣毛癣菌、絮状表皮癣菌3种常见致灰指甲真菌。具体方法为先将菌液与琼脂培养基注入平面皿，混合待凝，用无菌打孔器在琼脂培养皿上打直径为6mm的孔6个，挑出孔内琼脂，然后滴入经过稀释2倍的山茶油中药去灰甲油，每一孔约0.2ml，在25度条件下培养24h,观察抑菌圈的大小及真菌的活性的影响如表1，结果显示实验组对红色毛癣菌、须癣毛癣菌、絮状表皮癣菌3种皮肤致病真菌均有很强的抑菌和杀菌作用。
以上所述仅为本发明的实施例的制备及作用效果，凡是利用本说明书内容所做的同等变换，或直接或间接运用在相关的技术领域，均同理包括在本发明的专利保护范围内。

Claims (1)

1.一种山茶油中药去灰指甲油，其特征在于：其原料按重量分数比为：山茶油15-25份、花椒5-10份、青蒿5-10份、荜澄茄5-10份、肉桂5-10份、补骨脂5-10份、没药3-6份、知母3-6份、茵陈3-6份、苍耳子3-6份、厚朴3-6份；
其制备方法为：1）采用干燥的花椒、青蒿、没药、知母、茵陈、苍耳子、厚朴并进行粉碎在10-40目之间，分别在100度热水中浸提45分钟，过滤备用，料液比为1:6 ；肉桂、荜澄茄挥发油按原料比例分别采用挥发油提取器进行制备；补骨脂采用6倍质量的70%乙醇浸提1周，过滤；
2）在山茶油中分别加入花椒、青蒿、没药、知母、茵陈、苍耳子、厚朴、补骨脂中药浸提液进行 充分混匀，再加入无水乙醇至产品重量分数达到99份使产品的油相与水相充分融合不易分层，最后加入肉桂、荜澄茄挥发性油充分混匀并将产品进行保存。
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1101562A (zh) * 1993-10-15 1995-04-19 罗宏德 速效脚癣灵
CN101766697A (zh) * 2010-02-12 2010-07-07 吴新治 一种抗真菌治疗皮肤癣疾的药物及其制备方法

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Publication number Priority date Publication date Assignee Title
CN1101562A (zh) * 1993-10-15 1995-04-19 罗宏德 速效脚癣灵
CN101766697A (zh) * 2010-02-12 2010-07-07 吴新治 一种抗真菌治疗皮肤癣疾的药物及其制备方法

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