CN104524142A - Pharmaceutical composition for treating chronic urticaria - Google Patents
Pharmaceutical composition for treating chronic urticaria Download PDFInfo
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- CN104524142A CN104524142A CN201510051952.0A CN201510051952A CN104524142A CN 104524142 A CN104524142 A CN 104524142A CN 201510051952 A CN201510051952 A CN 201510051952A CN 104524142 A CN104524142 A CN 104524142A
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Abstract
The invention relates to a pharmaceutical composition for treating chronic urticaria. The pharmaceutical composition is prepared from the following medicinal raw materials in parts by weight: 150-200 parts of garden balsam herb, 100-150 parts of lithospermum arvense, 130-180 parts of hemistepta lyrata, 100-150 parts of glechoma longituba, 130-190 parts of pampanin shuteria herb, 100-150 parts of semen allii tuberose, 100-150 parts of sassafras, 100-150 parts of caulis spatholobi, 50-100 parts of bile arisaema, 50-100 parts of raspberries, 50-100 parts of fructus aurantii, 100-150 parts of funaria hygrometrica, 50-100 parts of polygonum cuspidatum, 150-200 parts of bauhinia championii, 130-170 parts of heliotropium indicum, 100-150 parts of wolfberry fruits, 150-200 parts of ipomoea pes-caprae, 80-130 parts of longans, 100-150 parts of lepisori herba, 80-120 parts of garden balsam stems, 50-80 parts of storax, 30-70 parts of spina gleditsiae, 100-150 parts of ainsliaefolious cacalia roots and 100-150 parts of liquorice. The pharmaceutical composition for treating chronic urticaria provided by the invention is reasonable in formula and has the characteristics of exact in curative effect, safe and convenient, free of toxic and side effects and low in cost.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of pharmaceutical composition for the treatment of chronic urticaria.
Background technology
Urticaria is a kind of allergic skin disease, is referred to as " rubella group " by people.Often have acute and chronic dividing clinically, the general course of disease just thought chronic urticaria more than 8 weeks.And the normal Relapse rate outbreak of chronic urticaria, delay is difficult, brings huge misery to patient.The method for the treatment of chronic urticaria is a lot of, and what doctor trained in Western medicine adopted is generally antihistaminic and glucocorticoid medicine, although temporarily can control symptom, relapse rate is high.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition for the treatment of chronic urticaria.
In order to realize object of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of chronic urticaria, it is made up by weight of following bulk drugs: water Impatientis 150-200 part, field Radix Arnebiae (Radix Lithospermi) 100-150 part, Herba Hemisteptae Lyratae 130-180 part, HUOXUEDAN 100-150 part, Shuteria pampaniniana Hand.-Mazz. 130-190 part, Semen Allii Tuberosi 100-150 part, Cinnamomum porrectum (Roxb.) Kosterm. 100-150 part, Caulis Spatholobi 100-150 part, Arisaema Cum Bile 50-100 part, Fructus Rubi 50-100 part, Fructus Aurantii 50-100 part, Herba Funariae Hygrometricae 100-150 part, Rhizoma Polygoni Cuspidati 50-100 part, Caulis Bauhihiae Championii 150-200 part, Herba Heliotroph 130-170 part, Fructus Lycii 100-150 part, Herba Ipomoeae Pes-Capraes 150-200 part, Arillus Longan 80-130 part, Herba Lepisori Thunbergiani 100-150 part, Herba speranskiae tuberculatae 80-120 part, Styrax 50-80 part, Spina Gleditsiae 30-70 part, Radix Cacaliae Ainsliaeflorae 100-150 part and Radix Glycyrrhizae 100-150 part.
Preferably, the pharmaceutical composition of described treatment chronic urticaria is made up by weight of following bulk drugs: water Impatientis 170 parts, field Radix Arnebiae (Radix Lithospermi) 120 parts, Herba Hemisteptae Lyratae 150 parts, HUOXUEDAN 130 parts, Shuteria pampaniniana Hand.-Mazz. 150 parts, Semen Allii Tuberosi 110 parts, Cinnamomum porrectum (Roxb.) Kosterm. 110 parts, Caulis Spatholobi 130 parts, Arisaema Cum Bile 60 parts, Fructus Rubi 80 parts, Fructus Aurantii 70 parts, Herba Funariae Hygrometricae 130 parts, Rhizoma Polygoni Cuspidati 80 parts, Caulis Bauhihiae Championii 180 parts, Herba Heliotroph 150 parts, Fructus Lycii 120 parts, Herba Ipomoeae Pes-Capraes 160 parts, Arillus Longan 100 parts, Herba Lepisori Thunbergiani 130 parts, Herba speranskiae tuberculatae 100 parts, Styrax 60 parts, Spina Gleditsiae 50 parts, Radix Cacaliae Ainsliaeflorae 120 parts and 120 parts, Radix Glycyrrhizae.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, lotion or ointment.
The present invention also provides the purposes of compositions in the medicine of preparation treatment chronic urticaria, described compositions is made up by weight of following bulk drugs: water Impatientis 150-200 part, field Radix Arnebiae (Radix Lithospermi) 100-150 part, Herba Hemisteptae Lyratae 130-180 part, HUOXUEDAN 100-150 part, Shuteria pampaniniana Hand.-Mazz. 130-190 part, Semen Allii Tuberosi 100-150 part, Cinnamomum porrectum (Roxb.) Kosterm. 100-150 part, Caulis Spatholobi 100-150 part, Arisaema Cum Bile 50-100 part, Fructus Rubi 50-100 part, Fructus Aurantii 50-100 part, Herba Funariae Hygrometricae 100-150 part, Rhizoma Polygoni Cuspidati 50-100 part, Caulis Bauhihiae Championii 150-200 part, Herba Heliotroph 130-170 part, Fructus Lycii 100-150 part, Herba Ipomoeae Pes-Capraes 150-200 part, Arillus Longan 80-130 part, Herba Lepisori Thunbergiani 100-150 part, Herba speranskiae tuberculatae 80-120 part, Styrax 50-80 part, Spina Gleditsiae 30-70 part, Radix Cacaliae Ainsliaeflorae 100-150 part and Radix Glycyrrhizae 100-150 part.
Preferably, described compositions is made up by weight of following bulk drugs: water Impatientis 170 parts, field Radix Arnebiae (Radix Lithospermi) 120 parts, Herba Hemisteptae Lyratae 150 parts, HUOXUEDAN 130 parts, Shuteria pampaniniana Hand.-Mazz. 150 parts, Semen Allii Tuberosi 110 parts, Cinnamomum porrectum (Roxb.) Kosterm. 110 parts, Caulis Spatholobi 130 parts, Arisaema Cum Bile 60 parts, Fructus Rubi 80 parts, Fructus Aurantii 70 parts, Herba Funariae Hygrometricae 130 parts, Rhizoma Polygoni Cuspidati 80 parts, Caulis Bauhihiae Championii 180 parts, Herba Heliotroph 150 parts, Fructus Lycii 120 parts, Herba Ipomoeae Pes-Capraes 160 parts, Arillus Longan 100 parts, Herba Lepisori Thunbergiani 130 parts, Herba speranskiae tuberculatae 100 parts, Styrax 60 parts, Spina Gleditsiae 50 parts, Radix Cacaliae Ainsliaeflorae 120 parts and 120 parts, Radix Glycyrrhizae.
Preferably, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, lotion or ointment.
In the present invention, water Impatientis, field Radix Arnebiae (Radix Lithospermi), Herba Hemisteptae Lyratae are monarch drug; HUOXUEDAN, Shuteria pampaniniana Hand.-Mazz., Semen Allii Tuberosi, Cinnamomum porrectum (Roxb.) Kosterm., Caulis Spatholobi, Arisaema Cum Bile are ministerial drug; Fructus Rubi, Fructus Aurantii, Herba Funariae Hygrometricae, Rhizoma Polygoni Cuspidati, Caulis Bauhihiae Championii, Herba Heliotroph, Fructus Lycii, Herba Ipomoeae Pes-Capraes, Arillus Longan, Herba Lepisori Thunbergiani, Herba speranskiae tuberculatae, Styrax, Spina Gleditsiae, Radix Cacaliae Ainsliaeflorae are adjuvant drug; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, plays the effect making medicine in the compositions of the present invention.All medicines are harmonious in the present invention, reasonable recipe, have determined curative effect, safe ready, have no side effect, cheap feature.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment lotion of the present invention
Take water Impatientis 170 grams, field Radix Arnebiae (Radix Lithospermi) 120 grams, Herba Hemisteptae Lyratae 150 grams, HUOXUEDAN 130 grams, Shuteria pampaniniana Hand.-Mazz. 150 grams, Semen Allii Tuberosi 110 grams, Cinnamomum porrectum (Roxb.) Kosterm. 110 grams, Caulis Spatholobi 130 grams, Arisaema Cum Bile 60 grams, Fructus Rubi 80 grams, Fructus Aurantii 70 grams, Herba Funariae Hygrometricae 130 grams, Rhizoma Polygoni Cuspidati 80 grams, Caulis Bauhihiae Championii 180 grams, Herba Heliotroph 150 grams, Fructus Lycii 120 grams, Herba Ipomoeae Pes-Capraes 160 grams, Arillus Longan 100 grams, Herba Lepisori Thunbergiani 130 grams, Herba speranskiae tuberculatae 100 grams, Styrax 60 grams, Spina Gleditsiae 50 grams, Radix Cacaliae Ainsliaeflorae 120 grams and 120 grams, Radix Glycyrrhizae, add 20 liters, water, heating 5 hours under the condition of backflow, filter, filtrate is made to be cooled to room temperature, obtain.
Experimental example
Select 80 routine chronic urticaria patients, wherein man 34 example, female 46 example; Age 19-62 year, average 38 years old; The course of disease 8 weeks-3 years, average 5.6 months.All patient age >14 one full year of life, with transient welt and skin pruritus for main clinic symptoms, there is welt time medical in the course of disease >=4 week.There is the one of following situations not as selected object: 1. have severe arrhythmia and organic heart disease patient; 2. oral in nearest 2 weeks or injected glucocorticoid or other Loratadines; 3. the infull person of serious Liver and kidney function is had; 4. age <14 one full year of life; 5. Pregnant and lactant women.
The lotion using embodiment to prepare is treated, every day 3 times, and each gauze that uses dips 200 milliliters of lotions, then covers position upper 5 minute of skin welt and pruritus.Continuous treatment 20 days.
Efficacy determination
According to the criterion of therapeutical effect evaluation of chronic urticaria in " Chinese medical disease Standardization of diagnosis and curative effect " (Zhao Yufu. Chinese traditional treatment chronic urticaria experience introduction [J]. Xinjiang Chinese medicine 2008,260): 82-83) formulate.Recovery from illness: welt disappears, clinical symptom disappearance, does not reaccess; Take a turn for the better: welt disappears >=30%, or after disappearing again recurrent interval time extend, the symptoms such as pruritus alleviate; Do not heal: welt and pruritus are not improved, or disappear less than 30%.
Therapeutic outcome
Through treatment, in discovery 80 routine patients, recovery from illness 58 example, take a turn for the better 20 examples, and do not heal 2 examples, and total effective rate is 97.5%.
Untoward reaction and toxic and side effects supervision
By detect patient blood pressure, pulse, whether there is Nausea and vomiting, dizzy clinical symptoms judges untoward reaction.Find that the systolic pressure of 80 routine patients is between 90-140mmHg, diastolic pressure is between 60-90mmHg, and pulse is 60-100 beat/min, and blood pressure and pulse all within normal range, and does not occur Nausea and vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that medicine does not have obvious toxic and side effects for human body.
Claims (6)
1. treat the pharmaceutical composition of chronic urticaria for one kind, it is characterized in that, it is made up by weight of following bulk drugs: water Impatientis 150-200 part, field Radix Arnebiae (Radix Lithospermi) 100-150 part, Herba Hemisteptae Lyratae 130-180 part, HUOXUEDAN 100-150 part, Shuteria pampaniniana Hand.-Mazz. 130-190 part, Semen Allii Tuberosi 100-150 part, Cinnamomum porrectum (Roxb.) Kosterm. 100-150 part, Caulis Spatholobi 100-150 part, Arisaema Cum Bile 50-100 part, Fructus Rubi 50-100 part, Fructus Aurantii 50-100 part, Herba Funariae Hygrometricae 100-150 part, Rhizoma Polygoni Cuspidati 50-100 part, Caulis Bauhihiae Championii 150-200 part, Herba Heliotroph 130-170 part, Fructus Lycii 100-150 part, Herba Ipomoeae Pes-Capraes 150-200 part, Arillus Longan 80-130 part, Herba Lepisori Thunbergiani 100-150 part, Herba speranskiae tuberculatae 80-120 part, Styrax 50-80 part, Spina Gleditsiae 30-70 part, Radix Cacaliae Ainsliaeflorae 100-150 part and Radix Glycyrrhizae 100-150 part.
2. the pharmaceutical composition for the treatment of chronic urticaria according to claim 1, it is characterized in that, it is made up by weight of following bulk drugs: water Impatientis 170 parts, field Radix Arnebiae (Radix Lithospermi) 120 parts, Herba Hemisteptae Lyratae 150 parts, HUOXUEDAN 130 parts, Shuteria pampaniniana Hand.-Mazz. 150 parts, Semen Allii Tuberosi 110 parts, Cinnamomum porrectum (Roxb.) Kosterm. 110 parts, Caulis Spatholobi 130 parts, Arisaema Cum Bile 60 parts, Fructus Rubi 80 parts, Fructus Aurantii 70 parts, Herba Funariae Hygrometricae 130 parts, Rhizoma Polygoni Cuspidati 80 parts, Caulis Bauhihiae Championii 180 parts, Herba Heliotroph 150 parts, Fructus Lycii 120 parts, Herba Ipomoeae Pes-Capraes 160 parts, Arillus Longan 100 parts, Herba Lepisori Thunbergiani 130 parts, Herba speranskiae tuberculatae 100 parts, Styrax 60 parts, Spina Gleditsiae 50 parts, Radix Cacaliae Ainsliaeflorae 120 parts and 120 parts, Radix Glycyrrhizae.
3. the pharmaceutical composition for the treatment of chronic urticaria according to claim 2, is characterized in that, described pharmaceutical composition can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, lotion or ointment.
4. the purposes of compositions in the medicine of preparation treatment chronic urticaria, it is characterized in that, described compositions is made up by weight of following bulk drugs: water Impatientis 150-200 part, field Radix Arnebiae (Radix Lithospermi) 100-150 part, Herba Hemisteptae Lyratae 130-180 part, HUOXUEDAN 100-150 part, Shuteria pampaniniana Hand.-Mazz. 130-190 part, Semen Allii Tuberosi 100-150 part, Cinnamomum porrectum (Roxb.) Kosterm. 100-150 part, Caulis Spatholobi 100-150 part, Arisaema Cum Bile 50-100 part, Fructus Rubi 50-100 part, Fructus Aurantii 50-100 part, Herba Funariae Hygrometricae 100-150 part, Rhizoma Polygoni Cuspidati 50-100 part, Caulis Bauhihiae Championii 150-200 part, Herba Heliotroph 130-170 part, Fructus Lycii 100-150 part, Herba Ipomoeae Pes-Capraes 150-200 part, Arillus Longan 80-130 part, Herba Lepisori Thunbergiani 100-150 part, Herba speranskiae tuberculatae 80-120 part, Styrax 50-80 part, Spina Gleditsiae 30-70 part, Radix Cacaliae Ainsliaeflorae 100-150 part and Radix Glycyrrhizae 100-150 part.
5. purposes according to claim 4, it is characterized in that, described compositions is made up by weight of following bulk drugs: water Impatientis 170 parts, field Radix Arnebiae (Radix Lithospermi) 120 parts, Herba Hemisteptae Lyratae 150 parts, HUOXUEDAN 130 parts, Shuteria pampaniniana Hand.-Mazz. 150 parts, Semen Allii Tuberosi 110 parts, Cinnamomum porrectum (Roxb.) Kosterm. 110 parts, Caulis Spatholobi 130 parts, Arisaema Cum Bile 60 parts, Fructus Rubi 80 parts, Fructus Aurantii 70 parts, Herba Funariae Hygrometricae 130 parts, Rhizoma Polygoni Cuspidati 80 parts, Caulis Bauhihiae Championii 180 parts, Herba Heliotroph 150 parts, Fructus Lycii 120 parts, Herba Ipomoeae Pes-Capraes 160 parts, Arillus Longan 100 parts, Herba Lepisori Thunbergiani 130 parts, Herba speranskiae tuberculatae 100 parts, Styrax 60 parts, Spina Gleditsiae 50 parts, Radix Cacaliae Ainsliaeflorae 120 parts and 120 parts, Radix Glycyrrhizae.
6. purposes according to claim 5, is characterized in that, described medicine can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, lotion or ointment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510051952.0A CN104524142A (en) | 2015-01-31 | 2015-01-31 | Pharmaceutical composition for treating chronic urticaria |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510051952.0A CN104524142A (en) | 2015-01-31 | 2015-01-31 | Pharmaceutical composition for treating chronic urticaria |
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| CN201510051952.0A Pending CN104524142A (en) | 2015-01-31 | 2015-01-31 | Pharmaceutical composition for treating chronic urticaria |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088106A (en) * | 1992-12-17 | 1994-06-22 | 四川省中药研究所 | Strong rash-disappearing antipruritic |
| CN1436542A (en) * | 2002-02-08 | 2003-08-20 | 黄希平 | Recipe of medicine for treating urticaria |
-
2015
- 2015-01-31 CN CN201510051952.0A patent/CN104524142A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088106A (en) * | 1992-12-17 | 1994-06-22 | 四川省中药研究所 | Strong rash-disappearing antipruritic |
| CN1436542A (en) * | 2002-02-08 | 2003-08-20 | 黄希平 | Recipe of medicine for treating urticaria |
Non-Patent Citations (4)
| Title |
|---|
| 唐伟东等: "慢性荨麻疹中医辨证施治体会", 《四川中医》 * |
| 宋业强等: "扶正消疹汤治疗慢性荨麻疹的临床研究", 《中国中医药科技》 * |
| 李广瑞: "慢性荨麻疹的中医治疗对策", 《中国中西医结合皮肤性病学杂志》 * |
| 雍玉皞等: "《江苏省名中医：龙家俊医案医论集》", 31 January 2011, 东南大学出版社 * |
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Application publication date: 20150422 |