CN104524078A - Chilblain prevention medicine - Google Patents

Chilblain prevention medicine Download PDF

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Publication number
CN104524078A
CN104524078A CN201510018799.1A CN201510018799A CN104524078A CN 104524078 A CN104524078 A CN 104524078A CN 201510018799 A CN201510018799 A CN 201510018799A CN 104524078 A CN104524078 A CN 104524078A
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chilblain
medicine
weight
glycerol
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黄琴
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
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    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K9/0012Galenical forms characterised by the site of application
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention discloses chilblain prevention medicine. The chilblain prevention medicine is made of, by weight, 18-30 parts of radish leaves, 10-20 parts of Chinese mugwort, 10-25 parts of eggplant branches, 12-22 parts of dragon's blood, 8-15 parts of campsis grandiflora, 1-5 parts of calomel, 5-12 parts of schizonepeta, 5-15 parts of Chinese starjasmine stems, 3-10 parts of honey, 2-8 parts of egg white and 5-12 parts of glycerinum. The chilblain prevention medicine contains the traditional Chinese medicine of the radish leaves, the Chinese mugwort, the eggplant branches, the dragon's blood, the campsis grandiflora, the schizonepeta and the Chinese starjasmine stems, so that the chilblain prevention medicine has the good effects of clearing away heat and toxic materials, removing stasis, promoting blood circulation to remove meridian obstruction, eliminating swelling and relieving itching, can improve blood circulation at the chilblain affected part, enables the qi and blood to run smoothly, and is good in chilblain prevention effect; by combining the functions of the calomel, the honey, the egg white and the glycerinum, the effects of disinfection, bacteria removal and moisture preserving are also achieved, the cost is low, and toxic and side effects are avoided.

Description

A kind of preventing chilblain medicine
Technical field
The present invention relates to a kind of medicine, be specifically related to a kind of preventing chilblain medicine.
Background technology
Chilblain (chilblain) is exposed to the localized erythema's inflammatory skin damage caused in cold environment for a long time, and be commonly encountered diseases in winter, patient has chilblain quality more, is generally mainly in finger, the back of the hand, auricle and buccal position.Turn warm rear spontaneous recovery to spring, but easily recur winter coming year.Typical case's skin lesion is that limitation refers to lid, Semen Viciae fabae size, the dark violet redness edemous speckle of protuberance or scleroma, indefinite border, edge cerise, the livid purple color of central authorities, the nervous light in surface, the fading of ice-cold, pressure of touching, go to press rear recovery comparatively slow, and local is with feeling of numbness, waste heat has scratchiness or aggravation.Course of disease mesocuticle is tear-away, hemorrhage, rotten to the corn or occur ulcer, finally forms paralysed trace or fibrosis.Chilblain easily recurs, more difficult short time radical cure.The medicine of existing treatment chilblain is less and therapeutic effect is good not, or the zest of medicine to people is larger; As the application number Chinese invention patent application that is 201310189283.4 disclose a kind of can the hand cream of anti-frostbite, the weight portion of each component is: macromolecule nutritive water 50-60 part, glycerol 15-25 part, diethanolamine 1-3 part, ethylene glycol tetraacetic disodium 2-3 part, tristerin 1-2 part, phenol tincture 3-5 part, vaseline 1-3 part, Jojoba oil 8-12 part, sodium hydroxide 14-16 part, vitamin B: 4-6 part, Radix Vladimiriae 10-20 part.Although the effect of this kind of preventing chilblain hand cream skin-moisturizing, skin is better, the effect of anti-treating chilblain is poor, and its component is chemical composition, has zest to the skin of people.
Summary of the invention
For above-mentioned deficiency, it is effective that technical problem to be solved by this invention is to provide a kind of anti-treating chilblain, not containing chemical constituent, to the non-irritating preventing chilblain medicine of the skin of people.
For solving the problem, the present invention is achieved through the following technical solutions:
A kind of preventing chilblain medicine, is made up of the raw material of following weight portion: Folium Raphani 18 ~ 30 parts, Qi Ai 10 ~ 20 parts, 10 ~ 25 parts, Fructus Solani melongenae branch, Sanguis Draxonis 12 ~ 22 parts, Flos Campsis 8 ~ 15 parts, Calomelas 1 ~ 5 part, Herba Schizonepetae 5 ~ 12 parts, Caulis Trachelospermi 5 ~ 15 parts, Mel 3 ~ 10 parts, 2 ~ 8 parts, Ovum Gallus domesticus album, glycerol 5 ~ 12 parts.
Above-mentioned preventing chilblain medicine, more preferably, be made up of the raw material of following weight portion: Folium Raphani 25 parts, Qi Ai 14 parts, 18 parts, Fructus Solani melongenae branch, Sanguis Draxonis 20 parts, Flos Campsis 11 parts, Calomelas 3 parts, Herba Schizonepetae 8 parts, Caulis Trachelospermi 9 parts, Mel 7 parts, 5 parts, Ovum Gallus domesticus album, glycerol 8 parts.
The method preparing described preventing chilblain medicine can be: 1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi first by weight, the Chinese liquor putting into 50 ~ 70 DEG C soaks 1 ~ 7 day, filter, obtain filtrate, filtrate is condensed into paste under vacuo; 2) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 1) obtained paste, stirs 5 ~ 10 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 800 ~ 1200 revs/min.
In such scheme, further, the method preparing described preventing chilblain medicine can also be:
1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi by weight, mixing, obtains Chinese herbal medicine, and add the water of Chinese herbal medicine gross weight 7 ~ 11 times, soak after 1 ~ 2 hour, big fire turns slow fire boiling 1.5 ~ 3 hours after boiling, filter, obtain a decoction liquor;
2) by step 1) in medicinal residues add the water of 5 ~ 10 times again, big fire turns slow fire boiling 1 ~ 2 hour after boiling, filter, obtain secondary decoction liquor;
3) merge once, secondary decoction liquor, after 100 ~ 300 mesh screen, be condensed into body of paste at 0.1 ~ 0.8MPa, at 50 DEG C;
4) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 3) obtained body of paste, stirs 5 ~ 10 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 800 ~ 1200 revs/min.
Using method is: get appropriate product uniform application of the present invention in affected part, one day 2 ~ 3 times, general continuous use takes effect for 3 to 5 days, and slight chilblain can be cured for 7 days.
Compared with existing preventing chilblain medicine, beneficial effect of the present invention is:
The present invention contains Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and these Chinese medicinal components of Caulis Trachelospermi, there is effect of good heat-clearing and toxic substances removing, eliminating stasis and resolving masses, promoting blood circulation to remove obstruction in the collateral, repellent antipruritic, the blood circulation in chilblain affected part can be improved, make QI-blood circulation unobstructed, preventing chilblain is effective; And in conjunction with the effect of Calomelas, Mel, Ovum Gallus domesticus album and glycerol, also have sterilization to go bacterium, the effect of moisturizing, and with low cost, have no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further explained, but is not limited to these embodiments.
Embodiment 1
A kind of preventing chilblain medicine, is made up of the raw material of following weight portion: Folium Raphani 18 parts, Qi Ai 20 parts, 10 parts, Fructus Solani melongenae branch, Sanguis Draxonis 22 parts, Flos Campsis 8 parts, Calomelas 5 parts, Herba Schizonepetae 5 parts, Caulis Trachelospermi 15 parts, Mel 3 parts, 8 parts, Ovum Gallus domesticus album, glycerol 12 parts;
The method preparing above-mentioned preventing chilblain medicine is: 1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi first by weight, the Chinese liquor putting into 70 DEG C soaks 1 day, filter, obtain filtrate, filtrate is condensed into paste under vacuo; 2) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 1) obtained paste, stirs 10 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 800 revs/min.
Embodiment 2
A kind of preventing chilblain medicine, is made up of the raw material of following weight portion: Folium Raphani 30 parts, Qi Ai 10 parts, 25 parts, Fructus Solani melongenae branch, Sanguis Draxonis 12 parts, Flos Campsis 15 parts, Calomelas 1 part, Herba Schizonepetae 12 parts, Caulis Trachelospermi 5 parts, Mel 10 parts, 2 parts, Ovum Gallus domesticus album, glycerol 5 parts;
The method preparing above-mentioned preventing chilblain medicine is:
1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi by weight, mixing, obtains Chinese herbal medicine, and add the water of Chinese herbal medicine gross weight 9 times, soak after 1.5 hours, big fire turns slow fire boiling 2 hours after boiling, filter, obtain a decoction liquor;
2) by step 1) in medicinal residues add the water of 8 times again, big fire turns slow fire boiling 1 hour after boiling, filter, obtain secondary decoction liquor
3) merge once, secondary decoction liquor, after 200 mesh screen, be condensed into body of paste at 0.5MPa, at 50 DEG C;
4) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 3) obtained body of paste, stirs 8 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 1000 revs/min.
Embodiment 3
A kind of preventing chilblain medicine, is made up of the raw material of following weight portion: Folium Raphani 25 parts, Qi Ai 14 parts, 18 parts, Fructus Solani melongenae branch, Sanguis Draxonis 20 parts, Flos Campsis 11 parts, Calomelas 3 parts, Herba Schizonepetae 8 parts, Caulis Trachelospermi 9 parts, Mel 7 parts, 5 parts, Ovum Gallus domesticus album, glycerol 8 parts;
The method preparing above-mentioned preventing chilblain medicine is: 1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi first by weight, the Chinese liquor putting into 50 DEG C soaks 7 days, filter, obtain filtrate, filtrate is condensed into paste under vacuo; 2) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 1) obtained paste, stirs 5 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 1200 revs/min.
Embodiment 4
A kind of preventing chilblain medicine, is made up of the raw material of following weight portion: Folium Raphani 20 parts, Qi Ai 12 parts, 22 parts, Fructus Solani melongenae branch, Sanguis Draxonis 18 parts, Flos Campsis 13 parts, Calomelas 4 parts, Herba Schizonepetae 10 parts, Caulis Trachelospermi 12 parts, Mel 5 parts, 7 parts, Ovum Gallus domesticus album, glycerol 10 parts;
The method preparing above-mentioned preventing chilblain medicine is:
1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi by weight, mixing, obtains Chinese herbal medicine, and add the water of Chinese herbal medicine gross weight 11 times, soak after 2 hours, big fire turns slow fire boiling 3 hours after boiling, filter, obtain a decoction liquor;
2) by step 1) in medicinal residues add the water of 10 times again, big fire turns slow fire boiling 2 hours after boiling, filter, obtain secondary decoction liquor
3) merge once, secondary decoction liquor, after 300 mesh screen, be condensed into body of paste at 0.1MPa, at 50 DEG C;
4) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 3) obtained body of paste, stirs 10 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 800 revs/min.
The Be very effective of anti-frostbite of the present invention, clinical trail 120 people, recidivist does not account for 90% in two years, is below model case.
Case 1
Huang, female, 17 years old.Since two thousand eight, often there is chilblain in face, with scratchiness, has a strong impact on appearance every year.In January, 2013 uses this medicine, uses after 5 days, and disappearing in the red and swollen place of chilblain, continues use after 12 days, heal completely, so far without relapse indications.
Case 2
Liao, man, 25 years old.From 18 years old time, often there is chilblain in foot and palm place every year, during lower than 0 DEG C, red and swollen serious, has blister.In December, 2012 uses this medicine, uses after 7 days, and blister heals, and continues use after 7 days, and disappearing in the red and swollen place of chilblain, continues use after 15 days, heal completely, so far without relapse indications.
Case 3
Just certain, male, 10 years old.From 8 years old time, often there is chilblain in auricle and palm place every year, red and swollen serious, and cause the symptom such as blister, decortication.In February, 2013 uses this medicine, uses after 3 days, and blister heals, and continues use after 5 days, and disappearing in the red and swollen place of chilblain, continues use after 10 days, heal completely, so far without relapse indications.

Claims (4)

1. a preventing chilblain medicine, it is characterized in that, be made up of the raw material of following weight portion: Folium Raphani 18 ~ 30 parts, Qi Ai 10 ~ 20 parts, 10 ~ 25 parts, Fructus Solani melongenae branch, Sanguis Draxonis 12 ~ 22 parts, Flos Campsis 8 ~ 15 parts, Calomelas 1 ~ 5 part, Herba Schizonepetae 5 ~ 12 parts, Caulis Trachelospermi 5 ~ 15 parts, Mel 3 ~ 10 parts, 2 ~ 8 parts, Ovum Gallus domesticus album, glycerol 5 ~ 12 parts.
2. preventing chilblain medicine according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Folium Raphani 25 parts, Qi Ai 14 parts, 18 parts, Fructus Solani melongenae branch, Sanguis Draxonis 20 parts, Flos Campsis 11 parts, Calomelas 3 parts, Herba Schizonepetae 8 parts, Caulis Trachelospermi 9 parts, Mel 7 parts, 5 parts, Ovum Gallus domesticus album, glycerol 8 parts.
3. the method preparing preventing chilblain medicine as claimed in claim 1 or 2 is: 1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi first by weight, the Chinese liquor putting into 50 ~ 70 DEG C soaks 1 ~ 7 day, filter, obtain filtrate, filtrate is condensed into paste under vacuo; 2) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 1) obtained paste, stirs 5 ~ 10 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 800 ~ 1200 revs/min.
4. the method preparing preventing chilblain medicine as claimed in claim 1 or 2 is:
1) take described Folium Raphani, Qi Ai, Fructus Solani melongenae branch, Sanguis Draxonis, Flos Campsis, Herba Schizonepetae and Caulis Trachelospermi by weight, mixing, obtains Chinese herbal medicine, and add the water of Chinese herbal medicine gross weight 7 ~ 11 times, soak after 1 ~ 2 hour, big fire turns slow fire boiling 1.5 ~ 3 hours after boiling, filter, obtain a decoction liquor;
2) by step 1) in medicinal residues add the water of 5 ~ 10 times again, big fire turns slow fire boiling 1 ~ 2 hour after boiling, filter, obtain secondary decoction liquor
3) merge once, secondary decoction liquor, after 100 ~ 300 mesh screen, be condensed into body of paste at 0.1 ~ 0.8MPa, at 50 DEG C;
4) take described Calomelas, Mel, Ovum Gallus domesticus album and glycerol by weight, and add step 3) obtained body of paste, stirs 5 ~ 10 minutes, then adds the antiseptic of 0.1%, homogenizing, get product after sterilizing under 800 ~ 1200 revs/min.
CN201510018799.1A 2015-01-14 2015-01-14 Chilblain prevention medicine Pending CN104524078A (en)

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CN107243072A (en) * 2017-04-28 2017-10-13 贵州益寿农业科技有限公司 A kind of skin care kibe ointment and preparation method thereof
CN108159256A (en) * 2018-01-29 2018-06-15 陕西杨凌陕特农业发展有限公司 A kind of honey Chinese herbal medicine unguentum perniosis agent and preparation method thereof

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CN107243072A (en) * 2017-04-28 2017-10-13 贵州益寿农业科技有限公司 A kind of skin care kibe ointment and preparation method thereof
CN108159256A (en) * 2018-01-29 2018-06-15 陕西杨凌陕特农业发展有限公司 A kind of honey Chinese herbal medicine unguentum perniosis agent and preparation method thereof

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