CN104523947A - External application powder for treating osteoarthritis, and preparation method thereof - Google Patents
External application powder for treating osteoarthritis, and preparation method thereof Download PDFInfo
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Abstract
The invention relates to an external application powder for treating osteoarthritis. The external application powder comprises, by weight, 9-30 parts of root of Cudrania cochinchinensis Kudo et Masam, 6-12 parts of Chinese angelica, 5-9 parts of Ligusticum wallichii, 10-15 parts of Medicinal Cyathula Root, 1-5 parts of Himalayan Teasel Root, 4-10 parts of rhizome of Whiteback Greenbrier, 4-9 parts of Pericarpium Zanthoxyli, 3-12 parts of Millettia dielsiana, 10-25 parts of Incised Notopterygium, 4-10 parts of leech, 2-7 parts of Trogopterus Dung, 3-9 parts of safflower and 3-9 parts of Huperzia serrata. The external application powder has a substantial effect on osteoarthritis, can relieve pains, and also can relax muscles and tendons, invigorate blood circulation condition qi blood and improve patients' weak physique caused by long term diseases; and local common medicinal materials are selected in the invention, so the external application powder is cheap, and mitigates the patients' economy burden.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially a kind of Dressed medicine powder for the treatment of osteoarthritis and preparation method thereof.
Background technology
Osteoarthritis is a kind of degeneration, be the articular cartilage degeneration damage because the factors such as increasing age, obesity, strain, wound, joint birth defect, joint deformity cause, joint margins and subchondral bone reactive hyperplasia, also known as osteoarthritis, degenerative osteoarthritis, senile arthritis, hypertrophiarthritis etc.Clinical manifestation is the arthralgia of slowly development, tenderness, stiff, arthroncus, limitation of activity and joint deformity etc.
According to or without local and whole body paathogenic factor, osteoarthritis is divided into constitutional and the large class of Secondary cases two.1. secondary osteoarthritis: (1) mechanicalness or anatomical abnormalities hip joint development are abnormal, slipped femoral epiphysis, neck of femur exception, multiple epiphyseal dysplasia, old fracture, Meniscectomy is postoperative, joint replacement is postoperative, acute and chronic trauma.(2) inflammatory arthritic illness suppurative arthritis, osteomyelitis, tuberculous arthritis, rheumatoid arthritis, seronegative spondyloanthropathy, behcet syndrome, Paget disease.(3) Developmental and Metabolic Disorder gout, Gaucher disease, diabetes, Progressive symmetric erythrokeratodermia hepatolenticular degeneration, chondrocalcinosis, hydroxyapatite crystal.(4) cryptorrhea acromegaly, gonadal hormone exception, hyperparathyroidism, hypothyroidism accompany myxedema, adrenal cortex function hyperfunction.(5) neurological deficits peripheral neuritis, syringomyelia, Charcot arthrosis.2. spontaneous osteoarthritis: the cause of disease of spontaneous osteoarthritis it be unclear that, may factor be relevant with advanced age, women, obesity, occupational excessively use etc.Clinical manifestation: cardinal symptom is arthralgia, often betides daystart, after movable, pain alleviates on the contrary, but as hyperactivity, pain can increase the weight of again.Another symptom is ankylosis, often appears at WA or after daytime, joint kept certain position for a long time in morning.Check the swelling of affected joints visible joint, tenderness, have friction sense or " click clatter " sound time movable, the person of being in a bad way can have amyotrophy and joint deformity.
In the invention of existing treatment osteoarthritis, Authorization Notice No. CN 102697883 B(application number 201210198859.9) Chinese patent disclose a kind of plaster for the treatment of osteoarthritis, it is characterized in that: it is formulated by the raw material of Chinese medicine of following weight portion, Semen Strychni 90, Radix Aconiti Kusnezoffii 90, Pterospermi Heterophylli 80, hang upside down pen 80, Radix Cudraniae 90, Herba Glechomae 90, Radix Ardisiae Crenatae 90, Fructus rhois chinensis 90, Herba sambuci chinensis 90, Pheretima 80, Semen Vaccariae 80, Caulis et folium stauntoniae 80, Caulis et Folium piperis 80, Herba Caryopteridis Incanae 30, Moschus 6, Styrax 9, by Semen Strychni 90, Radix Aconiti Kusnezoffii 90, Pterospermi Heterophylli 80, hang upside down pen 80, Radix Cudraniae 90, Herba Glechomae 90, Radix Ardisiae Crenatae 90, Fructus rhois chinensis 90, Herba sambuci chinensis 90, Pheretima 80, Semen Vaccariae 80, Caulis et folium stauntoniae 80, Caulis et Folium piperis 80, Herba Caryopteridis Incanae 30.Authorization Notice No. CN 103054996 B(application number 201210573291.4) Chinese patent disclose a kind of Chinese medicine for the treatment of damp-heat type osteoarthritis, it is characterized in that it is prepared from by the raw material of following weight portion: Semen Persicae 10-50, Flos Carthami 10-50, Cortex Phellodendri 10-50, Radix Et Rhizoma Rhei 10-50, QINGSONG 10-50, Radix Achyranthis Bidentatae 10-50 and Borneolum Syntheticum 1-10.
Summary of the invention
For the present situation of existing treatment osteoarthritis deficiency, an object of the present invention is the Dressed medicine powder providing treatment osteoarthritis, has easy absorption, the feature that pain relieving is fast, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Dressed medicine powder.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The Dressed medicine powder for the treatment of osteoarthritis, each crude drug is as follows, is weight portion: Radix Cudraniae 9-30, Radix Angelicae Sinensis 6-12, Rhizoma Chuanxiong 5-9, Radix Cyathulae 10-15, Radix Dipsaci 1-5, Herba Lycopodii 4-10, Fructus Zanthoxyli 4-9, Caulis Spatholobi 3-12, Rhizoma Et Radix Notopterygii 10-25, Hirudo 4-10, Oletum Trogopterori 2-7, Flos Carthami 3-9, Herba Lycopodii serrati 3-9.
The Dressed medicine powder for the treatment of osteoarthritis, preferred scheme is, each crude drug is as follows, be weight portion: Radix Cudraniae 15-25, Radix Angelicae Sinensis 7-10, Rhizoma Chuanxiong 6-8, Radix Cyathulae 12-14, Radix Dipsaci 2-4, Herba Lycopodii 6-8, Fructus Zanthoxyli 5-7, Caulis Spatholobi 5-10, Rhizoma Et Radix Notopterygii 15-20, Hirudo 6-9, Oletum Trogopterori 4-6, Flos Carthami 5-7, Herba Lycopodii serrati 5-7.
The Dressed medicine powder for the treatment of osteoarthritis, better preferred scheme is that each crude drug is as follows, is weight portion: Radix Cudraniae 20, Radix Angelicae Sinensis 8, Rhizoma Chuanxiong 7, Radix Cyathulae 13, Radix Dipsaci 3, Herba Lycopodii 7, Fructus Zanthoxyli 6, Caulis Spatholobi 7, Rhizoma Et Radix Notopterygii 18 parts, Hirudo 8, Oletum Trogopterori 5, Flos Carthami 6, Herba Lycopodii serrati 6.
The preparation method of above-mentioned Dressed medicine powder, preparation process is as follows:
(1) Hirudo is put into non iron container together with Fructus Zanthoxyli, be blended into rice vinegar, soak 36-48 hour, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fries to sliding sharp state, drops into the Hirudo after soaking and Fructus Zanthoxyli, stir-fry 3-8 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by Radix Cudraniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Dipsaci and Radix Cyathulae section, use yellow wine uniform spraying, be placed in vexed 20-40 minute in crock to mix with Oletum Trogopterori, put the interior low baking temperature of the pot dryouied and fry 10-20 minute, take out, dry in the air cool after be placed in mortar with step (1) gained crude drug together with, it is stand-by to grind to form smalls, mistake 80-120 mesh sieve;
(3) by Herba Lycopodii, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Flos Carthami and Herba Lycopodii serrati add in step (1) gained filtrate, mixing, after slightly vexed 20-40 minute, decocts with water 2 times, intense fire is fried open for the first time, turn 20-60 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 20-40 minute slowly, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stirs and decocts, and in time becoming thick paste, dry 1-3 hour at 50-70 DEG C, bottles and obtain Dressed medicine powder.
The preparation method of foregoing Dressed medicine powder, the consumption of step (1) rice vinegar is that the 1-5 of the total consumption of Hirudo and Fructus Zanthoxyli is doubly (preferred, the consumption of rice vinegar is 2-4 times of the total consumption of Hirudo and Fructus Zanthoxyli, and more preferably good, the consumption of rice vinegar is 3 times of the total consumption of Hirudo and Fructus Zanthoxyli).
The preparation method of foregoing Dressed medicine powder, step (1) is blended into rice vinegar, soaks 40-44 hour, filters (be preferably blended into rice vinegar, soak 42 hours, filter).
The preparation method of foregoing Dressed medicine powder, step (2) is placed in vexed 25-35 minute in crock and mixes with Oletum Trogopterori (preferred, to be placed in and to mix with Oletum Trogopterori in crock vexed 30 minutes).
The preparation method of foregoing Dressed medicine powder, step (2) is put the interior low baking temperature of the pot dryouied and is fried 13-18 minute (preferred, to put the interior low baking temperature of the pot dryouied and fry 15 minutes).
The preparation method of foregoing Dressed medicine powder, step (3), after slightly vexed 25-35 minute, decocts with water 2 times (preferred, after slightly vexed 30 minutes, to decoct with water 2 times).
The preparation method of foregoing Dressed medicine powder, step (4) is dry 1.5-2.5 hour (preferred, drying 2 hours at 60 DEG C) at 55-65 DEG C.
Using method: for making the present invention reach optimum therapeuticing effect, during use, gets Chinese powder medicine 20-40g of the present invention, mixes thoroughly with Oleum sesami, be applied on adhesive plaster, stick in affected part, within 1 day, changes once, within 5 days, is a course for the treatment of.
This Dressed medicine powder, can not only pain relieving to the Be very effective of osteoarthritis, can also relaxing muscles and tendons to promote blood circulation, and QI and blood regulating, improves the body constitution of patient's weakness because of chronic pain, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The Dressed medicine powder for the treatment of osteoarthritis, the pharmacological effect of each crude drug is respectively:
Hirudo: Hirudo, popular name Hirudo, growth and breeding in the freshwater of inland, be the medicinal aquatic animal of special type of Chinese tradition, the brewed rear traditional Chinese medical science of its dry products is used as medicine, and has the effect such as treatment apoplexy, hypertension, the clear stasis of blood, amenorrhea, traumatic injury.Salty hardship, flat, poisonous.The diseases such as menstruation apolipsis, lump in the abdomen stomachache, blood-retention, traumatic blood stasis are had a pain, carbuncle erysipelas.
Radix Cudraniae: light micro-hardship is cool.Expelling wind and removing dampness, promoting blood circulation to restore menstrual flow.Dispelling the wind and dampness pathogens arthralgia, jaundice, stranguria with turbid discharge, distention of the abdomen caused by various parasites, amenorrhea, impairment caused by overstrain hemoptysis, traumatic injury, furuncle carbuncle.
Radix Angelicae Sinensis: Radix Angelicae Sinensis another name is dryly returned, the Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Angelicae Sinensis body, contain that Radix Angelicae Sinensis, Radix Angelicae Sinensis are bent, Radix Angelicae Gigatis, sweet, pungent, warm, enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of main blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Chuanxiong: Rhizoma Chuanxiong cultivated plant, main product in Sichuan, in Yunnan, Guizhou, the ground such as Guangxi, be grown on gentle climatic environment.Be a kind of Chinese medicinal plant, be usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.
Radix Cyathulae: sweet in the mouth, micro-hardship, property is put down.Return liver, kidney channel.Effect eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Cure mainly: for amenorrhea lump in the abdomen, retention of placenta, injury from falling down, rheumatic arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, the cards such as hematuria stranguria with blood.
Radix Dipsaci: Radix Dipsaci, has another name called Radix Dipsaci, also name Radix Dipsaci, Chinese medicine name.For the root of herbaceos perennial Radix Dipsaci, invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.
Fructus Zanthoxyli: Fructus Zanthoxyli, calls large green pepper, Pericarpium Zanthoxyli, Pericarpium Zanthoxyli, southern green pepper, bar Jiao, Tang Yi etc.Pungent, warm, slightly poisonous, fiber crops.Warming middle-JIAO to relieve pain, killing parasites for relieving itching.For coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.
Caulis Spatholobi: be the another name of the various plants such as Schisandraceae, Sargentodoxaceae, Cuscutaceae, Papilionaceae.Bitter but slightly sweet taste, warm in nature, return liver, the heart, kidney channel; Red complexion enters blood, and matter profit row is loose; There is relaxing muscles and tendons to promote blood circulation, effect of nourishing blood for regulating menstruation; Cure mainly rheumatic arthralgia, numb hand and foot, quadriplegia, menoxenia, blockage of menstruation, dysmenorrhea, amenorrhea, leukopenia.
Rhizoma Et Radix Notopterygii: Rhizoma Et Radix Notopterygii, Chinese medicine name.Another name Qiang is blue or green, protect Qiang envoy, recklessly king envoy, Qiang is sliding, move back wind envoy, black powder, Umbelliferae, Notopterygium plant, and it is warm in nature, the cold expelling that induces sweat, dispelling cold and dampness, for affection of exogenous wind-cold, have a headache lossless, cold-damp numbness, upper limb rheumatalgia.
Oletum Trogopterori: Oletum Trogopterori has another name called medicine basis, number worm excrement of trembling with fear, Oletum Trogopterori are divided into Oletum Trogopterori rice, Oletum Trogopterori block (XUELINGZHI, sugared Oletum Trogopterori) two kinds.Sweet, temperature.Promoting blood circulation to remove blood stasis, parch to black stops blooding.Have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis; Traumatic injury is controlled in external, Serpentis, insect bite wound.
Flos Carthami: have promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contributes to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, skin infection swells and ache curative effect.Have blood circulation promoting and blood stasis dispelling, wet dissipation goes the effect swollen.
Herba Lycopodii serrati: Herba Lycopodii serrati, Chinese medicine name.For the herb of Huperziaceae stone araucaria herbaceos perennial Herba Lycopodii serrati.To gather at the beginning of late summer, autumn herb, remove earth, dry; Have effect of heat-clearing and toxic substances removing, promoting regeneration of the tissue and arresting bleeding, dissipating blood stasis for subsidence of swelling, control traumatic injury, swelling and pain due to blood stasis, hemorrhage due to internal injury, external is controlled carbuncle and is treated toxic swelling, venom, burn and scald etc.
Herba Lycopodii: bitter in the mouth, micro-pungent, warm in nature.There is expelling wind and removing dampness, effect of relaxing muscles and tendons and activating QI and blood in the collateral.
With Radix Angelicae Sinensis, Radix Cudraniae, Rhizoma Chuanxiong, Flos Carthami, Herba Lycopodii serrati wind-damp dispelling in the present invention, detumescence, pain relieving is main to control arthroncus, pain; By Hirudo, Radix Cyathulae, Radix Dipsaci, Oletum Trogopterori, Herba Lycopodii blood circulation promoting and blood stasis dispelling, dispelling, collateral-activating, promoting the circulation of QI to relieve pain, all medicines are harmonious, and bring out the best in each other, and have dispelling, collateral-activating, blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, except the function of wind dehumidifying, reach cure osteoarthritis rapidly.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the Dressed medicine powder for the treatment of osteoarthritis, each crude drug is as follows, is weight portion (getting 10g for every part): Radix Cudraniae 9, Radix Angelicae Sinensis 6, Rhizoma Chuanxiong 5, Radix Cyathulae 10, Radix Dipsaci 1, Herba Lycopodii 4, Fructus Zanthoxyli 4, Caulis Spatholobi 3, Rhizoma Et Radix Notopterygii 10, Hirudo 4, Oletum Trogopterori 2, Flos Carthami 3, Herba Lycopodii serrati 3.
The preparation method of the Dressed medicine powder of above-mentioned treatment osteoarthritis, step is:
(1) Hirudo is put into non iron container together with Fructus Zanthoxyli, be blended into rice vinegar, the consumption of rice vinegar is 1 times of the total consumption of Hirudo and Fructus Zanthoxyli, soak 36 hours, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the Hirudo after soaking and Fructus Zanthoxyli, stir-fry fast 3 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Radix Cudraniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Dipsaci and Radix Cyathulae section, use yellow wine uniform spraying, be placed in and mix with Oletum Trogopterori in crock vexed 20 minutes, put the interior low baking temperature of the pot dryouied and fry 10 minutes, take out, dry in the air cool after be placed in mortar with step (1) gained crude drug together with, it is stand-by to grind to form smalls, mistake 80 mesh sieves;
(3) by Herba Lycopodii, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Flos Carthami and Herba Lycopodii serrati add in step (1) gained filtrate, mixing, after slightly vexed 20 minutes, decocts with water 2 times, intense fire is fried open for the first time, turn 20 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 20 minutes slowly, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stirs and decocts, and in time becoming thick paste, at 50 DEG C, drying 1 hour, bottles and obtain Dressed medicine powder.
model case onezou XX, man, 40 years old, Harbin, Heilungkiang personage, peasant, nearly 1 year of two gonalgia, over nearly 1 month, right swelling and pain in knee obviously increased the weight of, and above all needs staircase downstairs, seat dysstasia, and meet overcast and rainy symptom obviously, morning is stiff, occasionally has interlocking phenomenon.Check: inner side tenderness under kneecap: left knee joint (+), right knee joint (++); Right knee joint is micro-swollen, right Range of motion of knee joint: 45 °; Tongue is greasy in vain, stringy and rolling pulse.Diagnosis: knee osteoarthritis.
Use embodiment 1 gained Dressed medicine powder, use 10 days two swelling and pain in knee obviously to alleviate, all the other symptoms are also in alleviation trend; Use 20 days, pain disappears, and can normally walk; Continue use 1 month malaise symptoms to disappear completely, follow up a case by regular visits to after half a year without recurrence.
embodiment 2the Dressed medicine powder for the treatment of osteoarthritis, each crude drug is as follows, is weight portion (getting 15g for every part): Radix Cudraniae 30, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 9, Radix Cyathulae 15, Radix Dipsaci 5, Herba Lycopodii 10, Fructus Zanthoxyli 9, Caulis Spatholobi 12, Rhizoma Et Radix Notopterygii 25, Hirudo 4-10, Oletum Trogopterori 7, Flos Carthami 9, Herba Lycopodii serrati 9.
The preparation method of the Dressed medicine powder of above-mentioned treatment osteoarthritis, step is:
(1) Hirudo is put into non iron container together with Fructus Zanthoxyli, be blended into rice vinegar, the consumption of rice vinegar is 5 times of the total consumption of Hirudo and Fructus Zanthoxyli, soak 48 hours, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the Hirudo after soaking and Fructus Zanthoxyli, stir-fry fast 8 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Radix Cudraniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Dipsaci and Radix Cyathulae section, use yellow wine uniform spraying, be placed in and mix with Oletum Trogopterori in crock vexed 40 minutes, put the interior low baking temperature of the pot dryouied and fry 20 minutes, take out, dry in the air cool after be placed in mortar with step (1) gained crude drug together with, it is stand-by to grind to form smalls, mistake 120 mesh sieves;
(3) by Herba Lycopodii, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Flos Carthami and Herba Lycopodii serrati add in step (1) gained filtrate, mixing, after slightly vexed 40 minutes, decocts with water 2 times, intense fire is fried open for the first time, turn 60 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 40 minutes slowly, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stirs and decocts, and in time becoming thick paste, at 70 DEG C, drying 3 hours, bottles and obtain Dressed medicine powder.
embodiment 3the Dressed medicine powder for the treatment of osteoarthritis, each crude drug is as follows, is weight portion (getting 20g for every part): Radix Cudraniae 15, Radix Angelicae Sinensis 7, Rhizoma Chuanxiong 6, Radix Cyathulae 12, Radix Dipsaci 2, Herba Lycopodii 6, Fructus Zanthoxyli 5, Caulis Spatholobi 5, Rhizoma Et Radix Notopterygii 15, Hirudo 6, Oletum Trogopterori 4, Flos Carthami 5, Herba Lycopodii serrati 5.
The preparation method of the Dressed medicine powder of above-mentioned treatment osteoarthritis, step is:
(1) Hirudo is put into non iron container together with Fructus Zanthoxyli, be blended into rice vinegar, the consumption of rice vinegar is 2 times of the total consumption of Hirudo and Fructus Zanthoxyli, soak 40 hours, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the Hirudo after soaking and Fructus Zanthoxyli, stir-fry fast 5 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Radix Cudraniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Dipsaci and Radix Cyathulae section, use yellow wine uniform spraying, be placed in and mix with Oletum Trogopterori in crock vexed 25 minutes, put the interior low baking temperature of the pot dryouied and fry 13 minutes, take out, dry in the air cool after be placed in mortar with step (1) gained crude drug together with, it is stand-by to grind to form smalls, mistake 90 mesh sieves;
(3) by Herba Lycopodii, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Flos Carthami and Herba Lycopodii serrati add in step (1) gained filtrate, mixing, after slightly vexed 25 minutes, decocts with water 2 times, intense fire is fried open for the first time, turn 30 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 25 minutes slowly, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stirs and decocts, and in time becoming thick paste, at 55 DEG C, drying 1.5 hours, bottles and obtain Dressed medicine powder.
model case twoliu XX, man, 60 years old, Jinan, Shandong Province city, retired aged teacher., existing 15 years of two knee joint sorenesses, have Knee Trauma history and history of catching cold.Though through treatments such as Chinese medicine and western medicine pain relievings, two knee joint sorenesses still time stop when doing, recently, knee joint soreness increases the weight of, and stair activity all needs handrail, and seat erects difficulty.X takes the photograph sheet prompting: knee joint is that bone is loose, and joint space narrows.Check: tenderness (+) around two knee joints, mild swelling and limping, two knee articulation degree are limited to 45 °, have interlocking to levy, McMurray's test (+), lateroflexion (±), floating kneecap (±).Diagnosis: knee osteoarthritis.
Use embodiment 3 gained Dressed medicine powder, use 10 days, rear two knee joints are ached and are alleviated, and swelling disappears, and all the other symptoms subtract; Use 20 days, malaise symptoms disappears substantially; Use again 1 first quarter moon as consolidation, after drug withdrawal, do not have any discomfort symptom, and appearance without any side effects during using embodiment 3 gained Dressed medicine powder.
embodiment 4the Dressed medicine powder for the treatment of osteoarthritis, each crude drug is as follows, is weight portion (getting 25g for every part): Radix Cudraniae 25, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 8, Radix Cyathulae 14, Radix Dipsaci 4, Herba Lycopodii 8, Fructus Zanthoxyli 7, Caulis Spatholobi 10, Rhizoma Et Radix Notopterygii 20, Hirudo 9, Oletum Trogopterori 6, Flos Carthami 7, Herba Lycopodii serrati 7.
The preparation method of the Dressed medicine powder of above-mentioned treatment osteoarthritis, step is:
(1) Hirudo is put into non iron container together with Fructus Zanthoxyli, be blended into rice vinegar, soak 44 hours, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fries to sliding sharp state, drops into the Hirudo after soaking and Fructus Zanthoxyli, stir-fry fast 7 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Radix Cudraniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Dipsaci and Radix Cyathulae section, use yellow wine uniform spraying, be placed in and mix with Oletum Trogopterori in crock vexed 35 minutes, put the interior low baking temperature of the pot dryouied and fry 18 minutes, take out, dry in the air cool after be placed in mortar with step (1) gained crude drug together with, it is stand-by to grind to form smalls, mistake 110 mesh sieves;
(3) by Herba Lycopodii, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Flos Carthami and Herba Lycopodii serrati add in step (1) gained filtrate, mixing, after slightly vexed 35 minutes, decocts with water 2 times, intense fire is fried open for the first time, turn 50 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 35 minutes slowly, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stirs and decocts, and in time becoming thick paste, at 65 DEG C, drying 2.5 hours, bottles and obtain Dressed medicine powder.
embodiment 5the Dressed medicine powder for the treatment of osteoarthritis, each crude drug is as follows, is weight portion (getting 30g for every part): Radix Cudraniae 20, Radix Angelicae Sinensis 8, Rhizoma Chuanxiong 7, Radix Cyathulae 13, Radix Dipsaci 3, Herba Lycopodii 7, Fructus Zanthoxyli 6, Caulis Spatholobi 7, Rhizoma Et Radix Notopterygii 18 parts, Hirudo 8, Oletum Trogopterori 5, Flos Carthami 6, Herba Lycopodii serrati 6.
The preparation method of the Dressed medicine powder of above-mentioned treatment osteoarthritis, step is:
(1) Hirudo is put into non iron container together with Fructus Zanthoxyli, be blended into rice vinegar, soak 42 hours, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fries to sliding sharp state, drops into the Hirudo after soaking and Fructus Zanthoxyli, stir-fry fast 6 minutes, take out, sieve shakeout, spreading for cooling;
(2) by Radix Cudraniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Dipsaci and Radix Cyathulae section, use yellow wine uniform spraying, be placed in and mix with Oletum Trogopterori in crock vexed 30 minutes, put the interior low baking temperature of the pot dryouied and fry 15 minutes, take out, dry in the air cool after be placed in mortar with step (1) gained crude drug together with, it is stand-by to grind to form smalls, mistake 100 mesh sieves;
(3) by Herba Lycopodii, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Flos Carthami and Herba Lycopodii serrati add in step (1) gained filtrate, mixing, after slightly vexed 30 minutes, decocts with water 2 times, intense fire is fried open for the first time, turn 40 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30 minutes slowly, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stirs and decocts, and in time becoming thick paste, at 60 DEG C, drying 2 hours, bottles and obtain Dressed medicine powder.
1,
experimental example:the clinical practice of the Dressed medicine powder of embodiment 5 gained treatment osteoarthritis: screen 300 routine patients in 4 hospitals, oldest 60 years old, minimal ages 40 years old, 50 years old mean age.Before test 1 week, carry out Continuous Observation to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 gained Dressed medicine powder, and matched group uses other medicine.Curative effect situation criterion: cure: malaise symptoms all disappears, effectively: after using this product, malaise symptoms alleviates or partial disappearance; Invalid: after using this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1:
Prove through clinical trial, Dressed medicine powder of the present invention is in treatment osteoarthritis, and effective percentage is 99%, cure rate is 97%, Dressed medicine powder instant effect of the present invention, can reach the object alleviating rapidly patient's misery, and relapse rate is low, it is a kind of Dressed medicine powder for the treatment of osteoarthritis safely and effectively.
Claims (10)
1. treat the Dressed medicine powder of osteoarthritis, it is characterized in that: each crude drug is as follows, is weight portion: Radix Cudraniae 9-30, Radix Angelicae Sinensis 6-12, Rhizoma Chuanxiong 5-9, Radix Cyathulae 10-15, Radix Dipsaci 1-5, Herba Lycopodii 4-10, Fructus Zanthoxyli 4-9, Caulis Spatholobi 3-12, Rhizoma Et Radix Notopterygii 10-25, Hirudo 4-10, Oletum Trogopterori 2-7, Flos Carthami 3-9, Herba Lycopodii serrati 3-9.
2. the Dressed medicine powder for the treatment of osteoarthritis according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Radix Cudraniae 15-25, Radix Angelicae Sinensis 7-10, Rhizoma Chuanxiong 6-8, Radix Cyathulae 12-14, Radix Dipsaci 2-4, Herba Lycopodii 6-8, Fructus Zanthoxyli 5-7, Caulis Spatholobi 5-10, Rhizoma Et Radix Notopterygii 15-20, Hirudo 6-9, Oletum Trogopterori 4-6, Flos Carthami 5-7, Herba Lycopodii serrati 5-7.
3. the Dressed medicine powder for the treatment of osteoarthritis according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Radix Cudraniae 20, Radix Angelicae Sinensis 8, Rhizoma Chuanxiong 7, Radix Cyathulae 13, Radix Dipsaci 3, Herba Lycopodii 7, Fructus Zanthoxyli 6, Caulis Spatholobi 7, Rhizoma Et Radix Notopterygii 18 parts, Hirudo 8, Oletum Trogopterori 5, Flos Carthami 6, Herba Lycopodii serrati 6.
4. the preparation method of the Dressed medicine powder according to any one of claim 1-3, is characterized in that: step is as follows:
(1) Hirudo is put into non iron container together with Fructus Zanthoxyli, be blended into rice vinegar, soak 36-48 hour, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fries to sliding sharp state, drops into the Hirudo after soaking and Fructus Zanthoxyli, stir-fry 3-8 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by Radix Cudraniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Dipsaci and Radix Cyathulae section, use yellow wine uniform spraying, be placed in vexed 20-40 minute in crock to mix with Oletum Trogopterori, put the interior low baking temperature of the pot dryouied and fry 10-20 minute, take out, dry in the air cool after be placed in mortar with step (1) gained crude drug together with, it is stand-by to grind to form smalls, mistake 80-120 mesh sieve;
(3) by Herba Lycopodii, Caulis Spatholobi, Rhizoma Et Radix Notopterygii, Flos Carthami and Herba Lycopodii serrati add in step (1) gained filtrate, mixing, after slightly vexed 20-40 minute, decocts with water 2 times, intense fire is fried open for the first time, turn 20-60 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 20-40 minute slowly, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stirs and decocts, and in time becoming thick paste, dry 1-3 hour at 50-70 DEG C, bottles and obtain Dressed medicine powder.
5. the preparation method of Dressed medicine powder according to claim 4, it is characterized in that: the consumption of step (1) rice vinegar is that the 1-5 of the total consumption of Hirudo and Fructus Zanthoxyli is doubly (preferred, the consumption of rice vinegar is 2-4 times of the total consumption of Hirudo and Fructus Zanthoxyli, more preferably good, the consumption of rice vinegar is 3 times of the total consumption of Hirudo and Fructus Zanthoxyli).
6. the preparation method of Dressed medicine powder according to claim 4, is characterized in that: step (1) is blended into rice vinegar, soaks 40-44 hour, filters (be preferably blended into rice vinegar, soak 42 hours, filter).
7. the preparation method of Dressed medicine powder according to claim 4, is characterized in that: step (2) is placed in vexed 25-35 minute in crock and mixes with Oletum Trogopterori (preferred, to be placed in and to mix with Oletum Trogopterori in crock vexed 30 minutes).
8. the preparation method of Dressed medicine powder according to claim 4, is characterized in that: step (2) is put the interior low baking temperature of the pot dryouied and fried 13-18 minute (preferred, to put the interior low baking temperature of the pot dryouied and fry 15 minutes).
9. the preparation method of Dressed medicine powder according to claim 4, is characterized in that: step (3), after slightly vexed 25-35 minute, decocts with water 2 times (preferred, after slightly vexed 30 minutes, to decoct with water 2 times).
10. the preparation method of Dressed medicine powder according to claim 4, is characterized in that: step (4) is dry 1.5-2.5 hour (preferred, drying 2 hours at 60 DEG C) at 55-65 DEG C.
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| CN105770977A (en) * | 2016-03-25 | 2016-07-20 | 张月媚 | Bandage for treating non-straightened joints after falling injury and preparation method thereof |
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