CN104510883A - Medicinal liquor for treating gouts, and preparation method thereof - Google Patents
Medicinal liquor for treating gouts, and preparation method thereof Download PDFInfo
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- CN104510883A CN104510883A CN201410217172.4A CN201410217172A CN104510883A CN 104510883 A CN104510883 A CN 104510883A CN 201410217172 A CN201410217172 A CN 201410217172A CN 104510883 A CN104510883 A CN 104510883A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention provides a medicinal liquor for treating gouts. The medicinal liquor is prepared through the following steps: removing impurities from Phalaris arundinacea, Aleuritopteris argentea, Atractylodes lancea, Amur Corktree Bark, safflower and Ligusticum wallichii, crushing, sieving by a 60 mesh sieve, immersing the obtained sieved medicinal materials in 30-50DEG liquor for 10-20d, and filtering to remove medicinal residues in order to prepare the medicinal liquor. The medicinal liquor has a gout treatment effect, has the advantages of simple formula, low cost and easy production, and is suitable for needs of most gout patients.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of medicated wine for the treatment of gout.
Background technology
Gout is that urate crystal deposits the pathological changes caused, and can involve foot, the most often involve Metatarsophalangeal joint, cause acute inflammatory reaction synovitis.Gout is that purine metabolic disturbance causes uric acid to synthesize to increase and the metabolic disease that causes.Also uric acid level can be caused to rise because the uric acid clearance of kidney declines during renal dysfunction.Uric acid in blood plasma reaches capacity, and causes monosodium urate crystallization deposition relatively to lack in the tissue of blood vessel around distal joint.The appearance of this crystallization can cause simple joint or multiarticulate acute inflammation synovitis.Gout is comparatively common in male, and big toe is modal affected area, and 50% ~ 70% first attack betides this.Metatarsophalangeal joint can be there is and get involved in the patient with gout of 90% in its certain period in life.Other foot area that may get involved have dorsal portion, heel and ankle.Except involving joint, uric acid crystal can also be deposited on subcutaneous, is referred to as tophus.Show as the serious pain of affected joints, swelling, erythema, stiff, heating during gouty attack,acute, and symptom occurs suddenly.Stage of attack, general last from days was by 1 week.There is no inducement during general morbidity, but can be secondary to mild trauma or edible be rich in the food of purine after.Gout is acute stage interior outbreak after surgery often.People are in the urgent need to a kind of effective, own medicated wine that can be played treatment gout by most people confirmation.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of medicated wine for the treatment of gout.
Technical scheme: the object of the invention is by following scheme realize:
Treat a medicated wine for gout, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Herba Pratiae Nummulariae 30-50 part, Aleuritopteris argentea (Gmel.) Fee 20-40 part, Rhizoma Atractylodis 10-20 part, Cortex Phellodendri 10-30 part, Flos Carthami 10-30 part, Rhizoma Chuanxiong 10-30 part and 30 °-50 ° Chinese liquor 5000-10000 parts.
The medicated wine of described treatment gout, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Herba Pratiae Nummulariae 40 parts, Aleuritopteris argentea (Gmel.) Fee 30 parts, Rhizoma Atractylodis 15 parts, Cortex Phellodendri 20 parts, 20 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts and 40 ° of Chinese liquor 7500 parts.
The medicated wine of described treatment gout, preparation method comprises the steps: to get the Herba Pratiae Nummulariae of recipe quantity, Aleuritopteris argentea (Gmel.) Fee, Rhizoma Atractylodis, Cortex Phellodendri, Flos Carthami, Ligusticum chuanxiong Hort, and remove impurity, pulverizing, after crossing 60 mesh sieves, put into 30 ° of-50 ° of Chinese liquor and soak 10-20 days, namely elimination medicinal residues obtain medicated wine.
In Chinese crude drug of the present invention, Herba Pratiae Nummulariae is Liliaceae Herba Reineckeae Carneae platymiscium Herba Reineckeae Carneae Reineckea carnea (Andr.) Kunth, with all herbal medicine.Aleuritopteris argentea (Gmel.) Fee is Valerianaceae valerian rock limit fragrant Valeriana hardwickii Wall., with root or all herbal medicine.All the other are pharmacopeia kind.
Beneficial effect:
1, from theory of Chinese medical science, Herba Pratiae Nummulariae expelling wind and removing dampness, relieving rigidity of muscles and knitting bone in we, Aleuritopteris argentea (Gmel.) Fee dredge the meridian passage is monarch drug altogether, and Rhizoma Atractylodis, Cortex Phellodendri dehumidifying, be ministerial drug, Flos Carthami and Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling are adjuvant, six compatibilities, and all medicines are harmonious, and can treat gout.
2, Formulation of the present invention is reasonable, and compatibility is rigorous, through long-term clinical verification, and determined curative effect.
3, the present invention consists of Chinese crude drug, has no side effect, low price.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, embodiment is prepared
Embodiment 1: get Herba Pratiae Nummulariae 30 parts, Aleuritopteris argentea (Gmel.) Fee 40 parts, Rhizoma Atractylodis 10 parts, Cortex Phellodendri 30 parts, 10 parts, Flos Carthami, Rhizoma Chuanxiong 30 parts of medical material remove impurity, pulverizing, after crossing 60 mesh sieves, put into 30 ° of Chinese liquor (10000 parts) and soak 10 days, namely elimination medicinal residues obtain medicated wine.
Embodiment 2: get Herba Pratiae Nummulariae 50 parts, Aleuritopteris argentea (Gmel.) Fee 20 parts, Rhizoma Atractylodis 20 parts, Cortex Phellodendri 10 parts, 30 parts, Flos Carthami, Rhizoma Chuanxiong 10 parts of medical material remove impurity, pulverizing, after crossing 60 mesh sieves, put into 40 ° of Chinese liquor (7500 parts) and soak 15 days, namely elimination medicinal residues obtain medicated wine.
Embodiment 3: get Herba Pratiae Nummulariae 40 parts, Aleuritopteris argentea (Gmel.) Fee 30 parts, Rhizoma Atractylodis 15 parts, Cortex Phellodendri 20 parts, 20 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts of medical material remove impurity, pulverizing, after crossing 60 mesh sieves, put into 50 ° of Chinese liquor (5000 parts) and soak 20 days, namely elimination medicinal residues obtain medicated wine.
2. pair gout pharmacodynamic study
2.1 experiment material
Sample preparation: prepare sample by above-described embodiment 2, namely Herba Pratiae Nummulariae 50 parts, Aleuritopteris argentea (Gmel.) Fee 20 parts, Rhizoma Atractylodis 20 parts, Cortex Phellodendri 10 parts, 30 parts, Flos Carthami, Rhizoma Chuanxiong 10 parts of medical material remove impurity, pulverizing is got, after crossing 60 mesh sieves, put into 40 ° of Chinese liquor (7500 parts) to soak 15 days, namely elimination medicinal residues obtain medicated wine.Specification is 100g//bottle.
Animal: ICR mice 50, male, body weight 18-22g, provides (laboratory animal production licence: SCXK (Soviet Union) 2002-0012 by Nanjing Medical University's Experimental Animal Center; Laboratory animal occupancy permit: SYXK (Soviet Union) 2002-0053).
Instrument and reagent: TG328A type photoelectric analytical balance (Shanghai balance equipment factory).Aspirin tablet, Nanjing Pharmaceutical Plant, lot number 20120216
2.2 granulation tissue hyperplasia tests
Grouping and experiment: divide 5 groups at random by 50 mices, i.e. model group, positive controls, the large, medium and small dosage group of the present invention, often group is 10, adopt the burying storage modeling of cotton balls oxter.
Administration: next day gastric infusion, continuous 7d, the large, medium and small dosage of the present invention; Positive controls is the same; Model group gavage 0.9% sodium chloride solution, volume is every 2ml, 30min after last administration, by sacrifice of animal, cotton balls granulation tissue is taken out, dries and weigh in 60 DEG C of baking boxs.Deduct cotton balls quality with cotton balls granulation tissue dry weight, be granulation tissue net weight.
Table 1 the present invention buries the impact (x ± s) bringing out granulation tissue hyperplasia on mice oxter cotton balls
Compare with negative control group, * 1P<0.01, * 2P<0.05
2.3 experiment conclusion: size dosed administration group of the present invention can alleviate granulation tissue weight, cotton balls oxter is buried and brings out granulation tissue hyperplasia and have obvious inhibitory action, compare with negative control group and have significant difference (P<0.01, P<0.05), show that the present invention has obvious antiinflammatory action.To sum up, the present invention has certain therapeutical effect to gout.
Claims (3)
1. treat the medicated wine of gout for one kind, it is characterized in that, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Herba Pratiae Nummulariae 30-50 part, Aleuritopteris argentea (Gmel.) Fee 20-40 part, Rhizoma Atractylodis 10-20 part, Cortex Phellodendri 10-30 part, Flos Carthami 10-30 part, Rhizoma Chuanxiong 10-30 part and 30 °-50 ° Chinese liquor 5000-10000 parts.
2. treat the medicated wine of gout as claimed in claim 1, it is characterized in that, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Herba Pratiae Nummulariae 40 parts, Aleuritopteris argentea (Gmel.) Fee 30 parts, Rhizoma Atractylodis 15 parts, Cortex Phellodendri 20 parts, 20 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts and 40 ° of Chinese liquor 7500 parts.
3. treat the medicated wine of gout as claimed in claim 1, it is characterized in that preparation method comprises the steps: to get the Herba Pratiae Nummulariae of recipe quantity, Aleuritopteris argentea (Gmel.) Fee, Rhizoma Atractylodis, Cortex Phellodendri, Flos Carthami, Ligusticum chuanxiong Hort, remove impurity, pulverizing, after crossing 60 mesh sieves, put into 30 ° of-50 ° of Chinese liquor and soak 10-20 days, namely elimination medicinal residues obtain medicated wine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410217172.4A CN104510883A (en) | 2014-05-21 | 2014-05-21 | Medicinal liquor for treating gouts, and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410217172.4A CN104510883A (en) | 2014-05-21 | 2014-05-21 | Medicinal liquor for treating gouts, and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN104510883A true CN104510883A (en) | 2015-04-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410217172.4A Pending CN104510883A (en) | 2014-05-21 | 2014-05-21 | Medicinal liquor for treating gouts, and preparation method thereof |
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| CN (1) | CN104510883A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748623A (en) * | 2016-04-29 | 2016-07-13 | 陶君 | Gout medicinal liquor and preparing method thereof |
| CN105748606A (en) * | 2016-04-29 | 2016-07-13 | 李钜芳 | Medicinal liquor for treating metabolic arthritis and preparation method thereof |
-
2014
- 2014-05-21 CN CN201410217172.4A patent/CN104510883A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748623A (en) * | 2016-04-29 | 2016-07-13 | 陶君 | Gout medicinal liquor and preparing method thereof |
| CN105748606A (en) * | 2016-04-29 | 2016-07-13 | 李钜芳 | Medicinal liquor for treating metabolic arthritis and preparation method thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150415 |
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| WD01 | Invention patent application deemed withdrawn after publication |